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Validated thin‐layer chromatographic method for the identification and monitoring of the effect of the extraction method on the yield and phytochemical constituents of Egyptian <italic>Withania somnifera</italic> leaves.
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- Journal of Separation Science, 2018, v. 41, n. 2, p. 518, doi. 10.1002/jssc.201700764
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- Article
Antiproliferative withanolides from the Solanaceae: A structure-activity study.
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- Pure & Applied Chemistry, 2012, v. 84, n. 6, p. 1353, doi. 10.1351/PAC-CON-11-10-08
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- Article
Withanolides from the genus Physalis: a review on their phytochemical and pharmacological aspects.
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- Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 5, p. 649, doi. 10.1111/jphp.13209
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- Article
Molecular characterization of three CYP450 genes reveals their role in withanolides formation and defense in Withania somnifera, the Indian Ginseng.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05634-9
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- Article
Therapeutic Applications of Physalins: Powerful Natural Weapons.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.864714
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- Article
Isolation and characterization of a bactericidal withanolide from Physalis virginiana.
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- Pharmacognosy Magazine, 2012, v. 8, n. 29, p. 22, doi. 10.4103/0973-1296.93307
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Withanolides are Potent Novel Targeted Therapeutic Agents Against Adrenocortical Carcinomas.
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- World Journal of Surgery, 2014, v. 38, n. 6, p. 1343, doi. 10.1007/s00268-014-2532-0
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- Article
Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling.
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- Angewandte Chemie International Edition, 2015, v. 54, n. 19, p. 5596, doi. 10.1002/anie.201500112
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- Article
Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications.
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- Journal of Food Quality, 2021, p. 1, doi. 10.1155/2021/8985179
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- Article
Optimization of Elicitation Conditions to Enhance the Production of Potent Metabolite Withanolide from Withania somnifera (L.).
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- Metabolites (2218-1989), 2022, v. 12, n. 9, p. 854, doi. 10.3390/metabo12090854
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- Article
Extraction Optimization for Phenolic- and Withanolide-Rich Fractions from Withania somnifera Roots: Identification and Quantification of Withaferin A, 12-Deoxywithastromonolide, and Withanolide A in Plant Materials and Marketed Formulations Using a Reversed-Phase HPLC-Photodiode Array Detection Method.
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- Journal of AOAC International, 2018, v. 101, n. 6, p. 1773, doi. 10.5740/jaoacint.18-0081
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Determination of Withanolides in Withania somnifera by Liquid Chromatography: Single-Laboratory Validation, First Action 2015.17.
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- Journal of AOAC International, 2017, v. 100, n. 1, p. 277, doi. 10.5740/jaoacint.2015.17
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- Article
Determination of Withanolides in Withania somnifera by Liquid Chromatography: Single-Laboratory Validation, First Action 2015.17.
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- Journal of AOAC International, 2016, v. 99, n. 6, p. 1444, doi. 10.5740/jaoacint.16-0202
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- Article
Withanolide Glycosides and Aglycones of Ashwagandha (Withania somnifera).
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- Journal of AOAC International, 2015, v. 98, n. 4, p. 1104, doi. 10.5740/jaoac.int.SMPR2015.007
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- Article
Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling.
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- Angewandte Chemie, 2015, v. 127, n. 19, p. 5688, doi. 10.1002/ange.201500112
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- Article
β-Amyloid<sub>1-42</sub>, HIV-1<sub>Ba-L</sub> (Clade B) Infection and Drugs of Abuse Induced Degeneration in Human Neuronal Cells and Protective Effects of Ashwagandha (Withania somnifera) and Its Constituent Withanolide A.
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- PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112818
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- Article
Withanolide A Prevents Neurodegeneration by Modulating Hippocampal Glutathione Biosynthesis during Hypoxia.
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- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0105311
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- Article
Enhanced Biosynthesis of Withanolides by Elicitation and Precursor Feeding in Cell Suspension Culture of <i>Withania somnifera</i> (L.) Dunal in Shake-Flask Culture and Bioreactor.
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- PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104005
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- Article
Differential Activities of the Two Closely Related Withanolides, Withaferin A and Withanone: Bioinformatics and Experimental Evidences.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044419
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- Article
A Novel MMP-2 Inhibitor 3-azidowithaferin A (3-azidoWA) Abrogates Cancer Cell Invasion and Angiogenesis by Modulating Extracellular Par-4.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044039
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Withanolides-Induced Breast Cancer Cell Death Is Correlated with Their Ability to Inhibit Heat Protein 90.
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- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037764
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- Article
Traditional Horticulture Practices Increase the Production of Selected Withanolides in Withania Somnifera (L.) Dunal—A RP-UFLC Analysis.
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- Journal of Chromatographic Science, 2020, v. 58, n. 10, p. 899, doi. 10.1093/chromsci/bmaa057
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- Article
RP-HPLC Separation of Isomeric Withanolides: Method Development, Validation and Application to In situ Rat Permeability Determination.
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- Journal of Chromatographic Science, 2017, v. 55, n. 7, p. 729, doi. 10.1093/chromsci/bmx027
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- Article
Accumulation of Three Important Bioactive Compounds in Different Plant Parts of Withania somnifera and its Determination by the LC–ESI-MS-MS (MRM) Method.
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- Journal of Chromatographic Science, 2015, v. 53, n. 10, p. 1749, doi. 10.1093/chromsci/bmv088
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- Article
Analysis of Major Withanolides in Physalis longifolia Nutt. by HPLC-PDA.
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- Journal of Chromatographic Science, 2015, v. 53, n. 7, p. 1044, doi. 10.1093/chromsci/bmu162
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- Article
Jasmonate responsive transcription factor WsMYC2 regulates the biosynthesis of triterpenoid withanolides and phytosterol via key pathway genes in Withania somnifera (L.) Dunal.
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- Plant Molecular Biology, 2019, v. 100, n. 4/5, p. 543, doi. 10.1007/s11103-019-00880-4
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- Article
Comprehensive assessment of the genes involved in withanolide biosynthesis from Withania somnifera: chemotype-specific and elicitor-responsive expression.
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- Functional & Integrative Genomics, 2017, v. 17, n. 4, p. 477, doi. 10.1007/s10142-017-0548-x
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- Article
Effects of moderate high temperature and UV-B on accumulation of withanolides and relative expression of the squalene synthase gene in Physalis peruviana.
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- Turkish Journal of Biology, 2020, v. 44, n. 5, p. 295, doi. 10.3906/biy-2002-69
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- Article
Effect of Ashwagandha Withanolides on Muscle Cell Differentiation.
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- Biomolecules (2218-273X), 2021, v. 11, n. 10, p. 1454, doi. 10.3390/biom11101454
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- Article
A BIOASSAY APPROACH TO COMPLEMENT CHEMICAL STANDARDIZATION OF ASHWAGANDHA ROOT EXTRACTS.
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- Rasayan Journal of Chemistry, 2022, v. 15, n. 4, p. 2258, doi. 10.31788/RJC.2022.1546980
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- Article
STUDY OF PHYTOCHEMICAL ACTIVE COMPOUNDS IN EXTRACT OF Withania somnifera.
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- Rasayan Journal of Chemistry, 2015, v. 8, n. 4, p. 522
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- Article
Coagulansin-A has beneficial effects on the development of bovine embryos in vitro via HSP70 induction.
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- Bioscience Reports, 2016, v. 36, n. 2, p. 1, doi. 10.1042/BSR20150222
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- Article
Comparative interactions of withanolides and sterols with two members of sterol glycosyltransferases from Withania somnifera.
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- BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0563-7
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- Article
In silico study of binding motifs in squalene synthase enzyme of secondary metabolic pathway solanaceae family.
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- Molecular Biology Reports, 2014, v. 41, n. 11, p. 7201, doi. 10.1007/s11033-014-3603-x
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- Article
Bioinformatics approaches for structural and functional analysis of proteins in secondary metabolism in Withania somnifera.
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- Molecular Biology Reports, 2014, v. 41, n. 11, p. 7323, doi. 10.1007/s11033-014-3618-3
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- Article
Dynamics of withanolide biosynthesis in relation to temporal expression pattern of metabolic genes in <i>Withania somnifera</i> (L.) Dunal: a comparative study in two morpho-chemovariants.
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- Molecular Biology Reports, 2013, v. 40, n. 12, p. 7007, doi. 10.1007/s11033-013-2820-z
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- Article
An Integrated Strategy of UHPLC-ESI-MS/MS Combined with Bioactivity-Based Molecular Networking for Identification of Antitumoral Withanolides from Athenaea fasciculata (Vell.) I.M.C. Rodrigues & Stehmann.
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- Molecules, 2024, v. 29, n. 18, p. 4357, doi. 10.3390/molecules29184357
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- Article
Novel Withanolides from Tubocapsicum anomalum Suppress Triple-Negative Breast Cancer by Triggering Apoptosis and p53-ASCT2-SLC7A11-Mediated Ferroptosis.
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- Molecules, 2024, v. 29, n. 8, p. 1838, doi. 10.3390/molecules29081838
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- Article
Chantriolides F–P, Highly Oxidized Withanolides with Hepatoprotective Activity from Tacca chantrieri.
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- Molecules, 2022, v. 27, n. 23, p. 8197, doi. 10.3390/molecules27238197
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- Article
Pharmacokinetic Study of Withanosides and Withanolides from Withania somnifera Using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-MS/MS).
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- Molecules, 2022, v. 27, n. 5, p. 1476, doi. 10.3390/molecules27051476
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- Article
Production and Structural Diversification of Withanolides by Aeroponic Cultivation of Plants of Solanaceae: Cytotoxic and Other Withanolides from Aeroponically Grown Physalis coztomatl.
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- Molecules, 2022, v. 27, n. 3, p. 909, doi. 10.3390/molecules27030909
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- Article
Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides.
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- Molecules, 2022, v. 27, n. 3, p. 886, doi. 10.3390/molecules27030886
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- Article
Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review.
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- Molecules, 2021, v. 26, n. 22, p. 6881, doi. 10.3390/molecules26226881
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- Article
INFLUENCE OF RHIZOPLANE AND RHIZOSPHERE BACTERIA ISOLATED FROM INFECTED PLANTS OF WITHANIA SOMNIFERA (DUNAL) IN BIOTRANSFORMATION OF WITHANOLIDES AND STEROLS.
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- Biochemical & Cellular Archives, 2023, v. 23, n. 2, p. 1235, doi. 10.51470/bca.2023.23.2.1235
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- Article
Biotechnological Intervention and Withanolide Production in Withania coagulans.
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- Agronomy, 2023, v. 13, n. 8, p. 1997, doi. 10.3390/agronomy13081997
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- Article
The cytochrome P450 enzyme WsCYP71B35 from Withania somnifera has a role in withanolides biosynthesis and defence against bacteria.
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- Physiologia Plantarum, 2024, v. 176, n. 1, p. 1, doi. 10.1111/ppl.14180
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- Article
Sterol partitioning by HMGR and DXR for routing intermediates toward withanolide biosynthesis.
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- Physiologia Plantarum, 2014, v. 152, n. 4, p. 617, doi. 10.1111/ppl.12213
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- Article
Discovery of physalin biosynthesis and structure modification of physalins in Physalis alkekengi L. var. Franchetii.
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- Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.956083
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- Article
Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal.
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- Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.917770
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- Article
Isolation of Active Fractions and Evaluting its Antidiabetic Property By Estimating Enzyme Inhibitory Activity of Withanolides from Withania coagulans.
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- Systematic Reviews in Pharmacy, 2023, v. 14, n. 8, p. 535, doi. 10.31858/0975-8453.14.8.535-538
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- Article