Works matching DE "WITHANOLIDES"

Results: 117

Validated thin‐layer chromatographic method for the identification and monitoring of the effect of the extraction method on the yield and phytochemical constituents of Egyptian <italic>Withania somnifera</italic> leaves.

Published in:

Journal of Separation Science, 2018, v. 41, n. 2, p. 518, doi. 10.1002/jssc.201700764

By:

Mahrous, Rahma S. R.;
Fathy, Hoda M.;
Abu EL‐Khair, Rasha M.;
Omar, Abdallah A.

Publication type:

Article

Withaferin A and its potential role in glioblastoma (GBM).

Published in:

Journal of Neuro-Oncology, 2017, v. 131, n. 2, p. 201, doi. 10.1007/s11060-016-2303-x

By:

Dhami, Jasdeep;
Chang, Edwin;
Gambhir, Sanjiv

Publication type:

Article

A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway Engineering.

Published in:

Frontiers in Plant Science, 2015, p. 1, doi. 10.3389/fpls.2015.01031

By:

Dhar, Niha;
Razdan, Sumeer;
Rana, Satiander;
Bhat, Wajid W.;
Vishwakarma, Ram;
Lattoo, Surrinder K.

Publication type:

Article

Withanolide D Exhibits Similar Cytostatic Effect in Drug-Resistant and Drug-Sensitive Multiple Myeloma Cells.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00610

By:

Issa, Mark E.;
Wijeratne, E. M. K.;
Gunatilaka, A. A. L.;
Cuendet, Muriel

Publication type:

Article

Evaluation of the bioavailability of major withanolides of Withania somnifera using an in vitro absorption model system.

Published in:

Journal of Advanced Pharmaceutical Technology & Research, 2015, v. 6, n. 4, p. 159, doi. 10.4103/2231-4040.165023

By:

Devkar, Santosh T.;
Kandhare, Amit D.;
Sloley, Brian D.;
Jagtap, Suresh D.;
Lin, James;
Tam, Yun K.;
Katyare, Surendra S.;
Bodhankar, Subhash L.;
Hegde, Mahabaleshwar V.

Publication type:

Article

Withaferin A inhibits inflammatory responses induced by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in macrophages.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 1, p. 983, doi. 10.3892/mmr.2016.5326

By:

EUI-JEONG NOH;
MING-JUNG KANG;
YU-JIN JEONG;
JUN-YOUNG LEE;
JUNG-HWAN PARK;
HYE-JIN CHOI;
SANG-MUK OH;
KYUNG-BOK LEE;
DONG-JAE KIM;
JI-AE SHIN;
SUNG-DAE CHO;
JONG-HWAN PARK

Publication type:

Article

Inhibitory effect of withaferin A on Helicobacter pylori-induced IL-8 production and NF-κB activation in gastric epithelial cells.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 1, p. 967, doi. 10.3892/mmr.2015.4602

By:

GREEN KIM;
TAE-HYOUN KIM;
MIN-JUNG KANG;
JIN-A CHOI;
DA-YOUNG PACK;
IK-RAE LEE;
MIN-GYU KIM;
SANG-SEOP HAN;
BO-YEON KIM;
SANG-MUK OH;
KYUNG-BOK LEE;
DONG-JAE KIM;
JONG-HWAN PARK

Publication type:

Article

Withanolides production by the endophytic fungus Penicillium oxalicum associated with Withania somnifera (L.) Dunal.

Published in:

World Journal of Microbiology & Biotechnology, 2024, v. 40, n. 7, p. 1, doi. 10.1007/s11274-024-04017-8

By:

Gupta, Anu;
Vasundhara, M.

Publication type:

Article

Identification Of Potential Cytotoxic Inhibitors From Physalis Minima.

Published in:

Natural Product Research, 2021, v. 35, n. 12, p. 2082, doi. 10.1080/14786419.2019.1650360

By:

Le Canh, Viet Cuong;
Le Ba, Vinh;
Thi Hai Yen, Pham;
Le Thi, Lien;
Thi Thuy Hoai, Pham;
Huu Dat, Ton That;
Thao, Do Thi;
Bach, Long Giang;
Kim, Young Ho;
Tuan Anh, Hoang Le

Publication type:

Article

Expression of Withania somnifera Steroidal Glucosyltransferase gene Enhances Withanolide Content in Hairy Roots.

Published in:

Plant Molecular Biology Reporter, 2016, v. 34, n. 3, p. 681, doi. 10.1007/s11105-015-0955-x

By:

Pandey, Vibha;
Srivastava, Rakesh;
Akhtar, Nehal;
Mishra, Jyoti;
Mishra, Pratibha;
Verma, Praveen

Publication type:

Article

Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 32, p. 8350, doi. 10.1002/chem.202100315

By:

Bonandi, Elisa;
Mori, Mattia;
Infante, Paola;
Basili, Irene;
Di Marcotullio, Lucia;
Calcaterra, Andrea;
Catti, Federica;
Botta, Bruno;
Passarella, Daniele

Publication type:

Article

Overexpression of squalene synthase in Withania somnifera leads to enhanced withanolide biosynthesis.

Published in:

Plant Cell, Tissue & Organ Culture, 2015, v. 122, n. 2, p. 409, doi. 10.1007/s11240-015-0778-3

By:

Patel, Neha;
Patel, Parth;
Kendurkar, Shuchishweta;
Thulasiram, Hirekodathakallu;
Khan, Bashir

Publication type:

Article

Improved production of withanolides in shoot suspension culture of Withania somnifera ( L.) Dunal by seaweed extracts.

Published in:

Plant Cell, Tissue & Organ Culture, 2014, v. 119, n. 1, p. 221, doi. 10.1007/s11240-014-0521-5

By:

Sivanandhan, Ganeshan;
Selvaraj, Natesan;
Ganapathi, Andy;
Manickavasagam, Markandan

Publication type:

Article

Increased production of withanolide A, withanone, and withaferin A in hairy root cultures of Withania somnifera (L.) Dunal elicited with methyl jasmonate and salicylic acid.

Published in:

Plant Cell, Tissue & Organ Culture, 2013, v. 114, n. 1, p. 121, doi. 10.1007/s11240-013-0297-z

By:

Sivanandhan, Ganeshan;
Kapil Dev, Gnanajothi;
Jeyaraj, Murugaraj;
Rajesh, Manoharan;
Arjunan, Annavi;
Muthuselvam, Manickam;
Manickavasagam, Markandan;
Selvaraj, Natesan;
Ganapathi, Andy

Publication type:

Article

A novel approach for direct shoot regeneration, anatomical characterization, and withanolides content in micropropagated plants of Withania somnifera (L.) Dunal—an important medicinal plant.

Published in:

In Vitro Cellular & Developmental Biology Plant, 2024, v. 60, n. 3, p. 365, doi. 10.1007/s11627-024-10428-x

By:

Mahendran, Ganesan;
Rahman, Laiq ur

Publication type:

Article

Oxidative Stress and AKT-Associated Angiogenesis in a Zebrafish Model and Its Potential Application for Withanolides.

Published in:

Cells (2073-4409), 2022, v. 11, n. 6, p. 961, doi. 10.3390/cells11060961

By:

Tang, Jen-Yang;
Cheng, Yuan-Bin;
Chuang, Ya-Ting;
Yang, Kun-Han;
Chang, Fang-Rong;
Liu, Wangta;
Chang, Hsueh-Wei

Publication type:

Article

A WRKY transcription factor from Withania somnifera regulates triterpenoid withanolide accumulation and biotic stress tolerance through modulation of phytosterol and defense pathways.

Published in:

New Phytologist, 2017, v. 215, n. 3, p. 1115, doi. 10.1111/nph.14663

By:

Singh, Anup Kumar;
Kumar, Sarma Rajeev;
Dwivedi, Varun;
Rai, Avanish;
Pal, Shaifali;
Shasany, Ajit K.;
Nagegowda, Dinesh A.

Publication type:

Article

Alterations in Withanolide Production in Withania Somnifera (l). Dunal Under Low Light Stress.

Published in:

Journal of Plant Science Research, 2014, v. 30, n. 2, p. 119

By:

Jacob, Lini;
R. V., Manju;
Stephen, Roy;
M. M., Viji;
Edison, Lekshmi K.

Publication type:

Article

HPTLC Quantification of Withaniasomnifera (L.) Dunal.

Published in:

Bulletin of Pure & Applied Sciences-Botany, 2022, v. 41A, n. 2, p. 117, doi. 10.5958/2320-3196.2022.00014.3

By:

Preet, Raman;
Lata

Publication type:

Article

Coagulansin-A has beneficial effects on the development of bovine embryos in vitro via HSP70 induction.

Published in:

Bioscience Reports, 2016, v. 36, n. 2, p. 1, doi. 10.1042/BSR20150222

By:

Imran Khan;
Kyeong-Lim Lee;
Fakruzzaman, Md;
Seok-Hwan Song;
Ihsan-ul-Haq;
Bushra Mirza;
Chang Guo Yan;
Il-Keun Kong

Publication type:

Article

In silico binding analysis of Withanolides with the Human GM-CSFR.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2016, v. 29, n. 4, p. 1279

By:

Kumar, Posa Krishnamoorthy Praveen;
Sivanandham, Muthukumaran;
Damodharan, Lavanya

Publication type:

Article

Molecular docking studies of withanolides against Cox-2 enzyme.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2012, v. 25, n. 3, p. 595

By:

Prabhakaran, Yogeswaran;
Dinakaran, Sathis Kumar;
Macharala, Sravan Prasad;
Ghosh, Somsubhra;
Karanam, Sridevi Ranjitha;
Kanthasamy, Naveena;
Avasarala, Harani

Publication type:

Article

Withalutin, a new cytotoxic withanolide from Athenaea velutina (Sendtn.) D'Arcy.

Published in:

Natural Product Research, 2022, v. 36, n. 24, p. 6304, doi. 10.1080/14786419.2022.2039135

By:

Almeida, Alisson A.;
Cota, Betania B.;
Rodrigues, Laís A.;
Dutra, Luana L.;
Kohlhoff, Markus;
Bressan, Gustavo C.;
Brandão, Geraldo C.;
Leite, João P. V.

Publication type:

Article

Comprehensive assessment of the genes involved in withanolide biosynthesis from Withania somnifera: chemotype-specific and elicitor-responsive expression.

Published in:

Functional & Integrative Genomics, 2017, v. 17, n. 4, p. 477, doi. 10.1007/s10142-017-0548-x

By:

Agarwal, Aditya;
Gupta, Parul;
Singh, Deeksha;
Dhar, Yogeshwar;
Chandra, Deepak;
Trivedi, Prabodh

Publication type:

Article

RNAi of Sterol Methyl Transferase1 Reveals its Direct Role in Diverting Intermediates Towards Withanolide/Phytosterol Biosynthesis in Withania somnifera.

Published in:

Plant & Cell Physiology, 2019, v. 60, n. 3, p. 672, doi. 10.1093/pcp/pcy237

By:

Pal, Shaifali;
Rastogi, Shubhra;
Nagegowda, Dinesh A.;
Gupta, Madan Mohan;
Shasany, Ajit Kumar;
Chanotiya, Chandan Singh

Publication type:

Article

The cytochrome P450 enzyme WsCYP71B35 from Withania somnifera has a role in withanolides biosynthesis and defence against bacteria.

Published in:

Physiologia Plantarum, 2024, v. 176, n. 1, p. 1, doi. 10.1111/ppl.14180

By:

Shilpashree, H. B.;
Narayanan, Ananth Krishna;
Kumar, Sarma Rajeev;
Barvkar, Vitthal;
Nagegowda, Dinesh A.

Publication type:

Article

Optimization of Elicitation Conditions to Enhance the Production of Potent Metabolite Withanolide from Withania somnifera (L.).

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 9, p. 854, doi. 10.3390/metabo12090854

By:

Singh, Manali;
Agrawal, Sanjeev;
Afzal, Obaid;
Altamimi, Abdulmalik S. A.;
Redhwan, Alya;
Alshammari, Nawaf;
Patel, Mitesh;
Adnan, Mohd;
Elasbali, Abdelbaset Mohamed;
Khan, Shahanavaj

Publication type:

Article

Withametelin inhibits TGF-β induced Epithelial-to-Mesenchymal Transition and Programmed-Death Ligand-1 expression in vitro.

Published in:

Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2024.1435516

By:

Fathima, Ashna;
Farboodniay Jahromi, Mohammad Ali;
Begum, Sajeli A.;
Jamma, Trinath

Publication type:

Article

Isolation of Active Fractions and Evaluting its Antidiabetic Property By Estimating Enzyme Inhibitory Activity of Withanolides from Withania coagulans.

Published in:

Systematic Reviews in Pharmacy, 2023, v. 14, n. 8, p. 535, doi. 10.31858/0975-8453.14.8.535-538

By:

Giri, Sumit Kumar;
Sonkusare, Sakshi Vidya;
Das, Nivedita

Publication type:

Article

Isolation of Active Fractions and Evaluting its Antidiabetic Property By Estimating Enzyme Inhibitory Activity of Withanolides from Withania coagulans.

Published in:

Systematic Reviews in Pharmacy, 2023, v. 14, n. 6, p. 437, doi. 10.31858/0975-8453.14.6.437-440

By:

Giri, Sumit Kumar;
Sonkusare, Sakshi Vidya;
Das, Nivedita

Publication type:

Article

Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168170

By:

Seth, Chandan;
Mas, Christophe;
Conod, Arwen;
Mueller, Jens;
Siems, Karsten;
Kuciak, Monika;
Borges, Isabel;
Ruiz i Altaba, Ariel

Publication type:

Article

RNAi and Homologous Over-Expression Based Functional Approaches Reveal Triterpenoid Synthase Gene-Cycloartenol Synthase Is Involved in Downstream Withanolide Biosynthesis in Withania somnifera.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149691

By:

Mishra, Smrati;
Bansal, Shilpi;
Mishra, Bhawana;
Sangwan, Rajender Singh;
Asha, null;
Jadaun, Jyoti Singh;
Sangwan, Neelam S.

Publication type:

Article

Withanolides are Potent Novel Targeted Therapeutic Agents Against Adrenocortical Carcinomas.

Published in:

World Journal of Surgery, 2014, v. 38, n. 6, p. 1343, doi. 10.1007/s00268-014-2532-0

By:

Subramanian, Chitra;
Zhang, Huaping;
Gallagher, Robert;
Hammer, Gary;
Timmermann, Barbara;
Cohen, Mark

Publication type:

Article

Simultaneous Determination of Withanolide A and Bacoside A in Spansules by High-Performance Thin-Layer Chromatography.

Published in:

Indian Journal of Pharmaceutical Sciences, 2011, v. 73, n. 2, p. 240, doi. 10.4103/0250-474X.91573

By:

Shinde, P. B.;
Aragade, P. D.;
Agrawal, M. R.;
Deokate, U. A.;
Khadabadi, S. S.

Publication type:

Article

The Impact of Ashwagandha Supplementation on Stress Biomarkers During a 12-Week Resistance Training Program: A Randomized Double-Blind Controlled Trial.

Published in:

German Journal of Sports Medicine / Deutsche Zeitschrift fur Sportmedizin, 2025, v. 76, n. 3, p. 69

By:

Köstler, D.;
Thull, P.;
Nolte, J.;
de Marées, M.;
Platen, P.

Publication type:

Article

Critical factors influencing in vitro propagation and modulation of important secondary metabolites in Withania somnifera (L.) dunal.

Published in:

Plant Cell, Tissue & Organ Culture, 2022, v. 149, n. 1/2, p. 41, doi. 10.1007/s11240-021-02225-w

By:

Kaur, Kuldeep;
Dolker, Dechen;
Behera, Shashikanta;
Pati, Pratap Kumar

Publication type:

Article

Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.917770

By:

Thorat, Sachin Ashok;
Kaniyassery, Arya;
Poojari, Poornima;
Rangel, Melissa;
Tantry, Shashikala;
Kiran, Kodsara Ramachandra;
Joshi, Manjunath B.;
Rai, Padmalatha S.;
Botha, Anna-Maria;
Muthusamy, Annamalai

Publication type:

Article

Organic cultivation of Ashwagandha with improved biomass and high content of active Withanolides: Use of Vermicompost.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0194314

By:

Kaur, Amandeep;
Singh, Baldev;
Ohri, Puja;
Wang, Jia;
Wadhwa, Renu;
Kaul, Sunil C.;
Pati, Pratap Kumar;
Kaur, Arvinder

Publication type:

Article

Oxidative Stress Induced NMDA Receptor Alteration Leads to Spatial Memory Deficits in Temporal Lobe Epilepsy: Ameliorative Effects of Withania somnifera and Withanolide A.

Published in:

Neurochemical Research, 2012, v. 37, n. 9, p. 1915, doi. 10.1007/s11064-012-0810-5

By:

Soman, Smijin;
Korah, P.;
Jayanarayanan, S.;
Mathew, Jobin;
Paulose, C.

Publication type:

Article

Ashwagandha & Mental Health: Combatting Depression And Insomnia Naturally.

Published in:

Eurasian Journal of Analytical Chemistry, 2024, v. 19, n. 1, p. 467

By:

Shrinidhi, V. V.;
Vyas, Krupa;
Patani, Pragnesh;
Solanki, Vijay

Publication type:

Article

Withanolides of the Aerial Part of Datura stramonium Growing in Uzbekistan and Cytotoxicity of Daturametelin H.

Published in:

Pharmaceutical Chemistry Journal, 2024, v. 58, n. 5, p. 833, doi. 10.1007/s11094-024-03212-z

By:

Makhmudova, M. M.;
Abdurakhmanov, B. A.;
Khalilov, R. M.;
Bobaev, I. D.;
Bobakulov, Kh. M.;
Sotimov, G. B.;
Abdullaev, N. D.;
Terent'eva, E. O.

Publication type:

Article

Effects of moderate high temperature and UV-B on accumulation of withanolides and relative expression of the squalene synthase gene in Physalis peruviana.

Published in:

Turkish Journal of Biology, 2020, v. 44, n. 5, p. 295, doi. 10.3906/biy-2002-69

By:

ŞAHİN, Günce;
TELLİ, Murat;
ÜNLÜ, Ercan Selçuk;
PEHLİVAN KARAKAŞ, Fatma

Publication type:

Article

HSCCC Straightforward Fast Preparative Method for Isolation of Two Major Cytotoxic Withanolides from Athenaea fasciculata (Vell.) I.M.C. Rodrigues & Stehmann.

Published in:

Plants (2223-7747), 2024, v. 13, n. 21, p. 3039, doi. 10.3390/plants13213039

By:

Marques, André Mesquita;
Brito, Lavínia de Carvalho;
Figueiredo, Maria Raquel

Publication type:

Article

Enhancing Withanolide Production in the Withania Species: Advances in In Vitro Culture and Synthetic Biology Approaches.

Published in:

Plants (2223-7747), 2024, v. 13, n. 15, p. 2171, doi. 10.3390/plants13152171

By:

Ahmad, Zishan;
Shareen;
Ganie, Irfan Bashir;
Firdaus, Fatima;
Ramakrishnan, Muthusamy;
Shahzad, Anwar;
Ding, Yulong

Publication type:

Article

Therapeutic Applications of Physalins: Powerful Natural Weapons.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.864714

By:

Meira, Cássio Santana;
Soares, José Waldson Capinan;
dos Reis, Bruna Padilha Zurita Claro;
Pacheco, Luciano Vasconcellos;
Santos, Ivanilson Pimenta;
Silva, Dahara Keyse Carvalho;
de Lacerda, Julia Costa;
Daltro, Sérgio Ricardo Teixeira;
Guimarães, Elisalva Teixeira;
Soares, Milena Botelho Pereira

Publication type:

Article

Nematicidal Activity of Withanolides from Withania coagulans (Stocks) Dunal against Meloidogyne incognita (Tylenchida: Heteroderidae).

Published in:

Pakistan Journal of Nematology, 2022, v. 40, n. 1, p. 80

By:

Mehar, Saima;
Javed, Salma

Publication type:

Article

A BIOASSAY APPROACH TO COMPLEMENT CHEMICAL STANDARDIZATION OF ASHWAGANDHA ROOT EXTRACTS.

Published in:

Rasayan Journal of Chemistry, 2022, v. 15, n. 4, p. 2258, doi. 10.31788/RJC.2022.1546980

By:

Singh, Vineet Kumar;
Mundkinajeddu, Deepak;
Koshy, Rojison;
Bhat, Deeksha;
J., Nithin;
Balaji, K. R.;
A. G., Gayathri

Publication type:

Article

Transcriptome analysis reveals in vitro cultured Withania somnifera leaf and root tissues as a promising source for targeted withanolide biosynthesis.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 520, doi. 10.1186/s12864-015-1214-0

By:

Senthil, Kalaiselvi;
Jayakodi, Murukarthick;
Thirugnanasambantham, Pankajavalli;
Sang Choon Lee;
Duraisamy, Pradeepa;
Purushotham, Preethi M.;
Rajasekaran, Kalaiselvi;
Charles, Shobana Nancy;
Roy, Irene Mariam;
Nagappan, Arul Kumar;
Gon Sup Kim;
Yun Sun Lee;
Natesan, Senthil;
Tae-Sun Min;
Tae Jin Yang

Publication type:

Article

Comparative interactions of withanolides and sterols with two members of sterol glycosyltransferases from Withania somnifera.

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0563-7

By:

Pandey, Vibha;
Dhar, Yogeshwar Vikram;
Gupta, Parul;
Bag, Sumit K.;
Atri, Neelam;
Asif, Mehar Hasan;
Trivedi, Prabodh Kumar;
Misra, Pratibha

Publication type:

Article

Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications.

Published in:

2021

By:

Sharifi-Rad, Javad;
Quispe, Cristina;
Ayatollahi, Seyed Abdulmajid;
Kobarfard, Farzad;
Staniak, Mariola;
Stępień, Anna;
Czopek, Katarzyna;
Sen, Surjit;
Acharya, Krishnendu;
Matthews, Karl R.;
Sener, Bilge;
Devkota, Hari Prasad;
Kırkın, Celale;
Özçelik, Beraat;
Victoriano, Montserrat;
Martorell, Miquel;
Rasul Suleria, Hafiz Ansar;
Alshehri, Mohammed M.;
Chandran, Deepak;
Kumar, Manoj

Publication type:

Literature Review