Works about VIRUS-induced enzymes

Results: 302

Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.

Published in:

PLoS Biology, 2005, v. 3, n. 9, p. 1, doi. 10.1371/journal.pbio.0030324

By:

Yang, Haitao;
Xie, Weiqing;
Xue, Xiaoyu;
Yang, Kailin;
Ma, Jing;
Liang, Wenxue;
Zhao, Qi;
Zhou, Zhe;
Pei, Duanqing;
Ziebuhr, John;
Hilgenfeld, Rolf;
Yuen, Kwok Yung;
Wong, Luet;
Gao, Guangxia;
Chen, Saijuan;
Chen, Zhu;
Ma, Dawei;
Bartlam, Mark;
Rao, Zihe

Publication type:

Article

Intracellular drug delivery using poly(d,l-lactide-co-glycolide) nano- particles derivatized with a peptide from a transcriptional activator protein of HIV-1.

Published in:

Biotechnology Letters, 2002, v. 24, n. 24, p. 2093, doi. 10.1023/A:1021373731787

By:

Nam, Yoon Sung;
Park, Ju Young;
Han, Sang-Hoon;
Chang, Ih-Seop

Publication type:

Article

Molecular Investigations of Novel Pyrano[2,3-c]Pyrazole Congeners as Potential HCoV-229E Inhibitors: synthesis, Molecular Modeling, 3D QSAR, and ADMET Screening.

Published in:

Polycyclic Aromatic Compounds, 2025, v. 45, n. 2, p. 251, doi. 10.1080/10406638.2024.2403544

By:

G. Abouelenein, Mohamed;
H. El-boghdady, Aliaa;
M. Ali, Hadeer;
A. Said, Mohamed

Publication type:

Article

Agathis robusta Bark Essential Oil Effectiveness against COVID-19: Chemical Composition, In Silico and In Vitro Approaches.

Published in:

Plants (2223-7747), 2022, v. 11, n. 5, p. N.PAG, doi. 10.3390/plants11050663

By:

Mohamed, Maged E.;
Tawfeek, Nora;
Elbaramawi, Samar S.;
Fikry, Eman

Publication type:

Article

Potential Inhibitor of DENV-2 Virus Protease (NS2B-NS3): An In-Silico Studies of Anti-Viral Plants.

Published in:

Journal of Drug Delivery & Therapeutics, 2024, v. 14, n. 11, p. 10, doi. 10.22270/jddt.v14i11.6870

By:

Rhakho, Mhashevolu

Publication type:

Article

Kinetic characterization of human mRNA guanine-N7 methyltransferase.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55184-5

By:

Perveen, Sumera;
Yazdi, Aliakbar Khalili;
Hajian, Taraneh;
Li, Fengling;
Vedadi, Masoud

Publication type:

Article

Identification and validation of fusidic acid and flufenamic acid as inhibitors of SARS-CoV-2 replication using DrugSolver CavitomiX.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39071-z

By:

Hetmann, M.;
Langner, C.;
Durmaz, V.;
Cespugli, M.;
Köchl, K.;
Krassnigg, A.;
Blaschitz, K.;
Groiss, S.;
Loibner, M.;
Ruau, D.;
Zatloukal, K.;
Gruber, K.;
Steinkellner, G.;
Gruber, C. C.

Publication type:

Article

Novel Viral DNA Polymerases From Metagenomes Suggest Genomic Sources of Strand-Displacing Biochemical Phenotypes.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.858366

By:

Keown, Rachel A.;
Dums, Jacob T.;
Brumm, Phillip J.;
MacDonald, Joyanne;
Mead, David A.;
Ferrell, Barbra D.;
Moore, Ryan M.;
Harrison, Amelia O.;
Polson, Shawn W.;
Wommack, K. Eric

Publication type:

Article

Tailored Nanoparticles With the Potential to Reduce Ruminant Methane Emissions.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.816695

By:

Altermann, Eric;
Reilly, Kerri;
Young, Wayne;
Ronimus, Ron S.;
Muetzel, Stefan

Publication type:

Article

Virus-induced complement activation and neutrophil-mediated cytotoxicity against respiratory syncytial virus (RSV).

Published in:

Clinical & Experimental Immunology, 1984, v. 56, n. 3, p. 501

By:

Kaul, T. N.;
Faden, H.;
Baker, R.;
Ogra, P. L.

Publication type:

Article

POM as a quick bioinformatic platform to select flavonoids and their metabolites as potential and efficient HIV-1 integrase inhibitors.

Published in:

Research on Chemical Intermediates, 2013, v. 39, n. 3, p. 1227, doi. 10.1007/s11164-012-0679-6

By:

Hadda, Taibi;
Fergoug, Teffaha;
Warad, Ismail;
Masand, Vijay;
Sheikh, Javed

Publication type:

Article

Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38555-w

By:

Durieux Trouilleton, Quentin;
Barata-García, Sergio;
Arragain, Benoît;
Reguera, Juan;
Malet, Hélène

Publication type:

Article

Monitoring the Bystander Killing Effect of Human Multipotent Stem Cells for Treatment of Malignant Brain Tumors.

Published in:

Thrombosis, 2016, p. 1, doi. 10.1155/2016/4095072

By:

Leten, Cindy;
Trekker, Jesse;
Struys, Tom;
Roobrouck, Valerie D.;
Dresselaers, Tom;
Vande Velde, Greetje;
Lambrichts, Ivo;
Verfaillie, Catherine M.;
Himmelreich, Uwe

Publication type:

Article

Targeting the DENV NS2B-NS3 protease with active antiviral phytocompounds: structure-based virtual screening, molecular docking and molecular dynamics simulation studies.

Published in:

Journal of Molecular Modeling, 2022, v. 28, n. 11, p. 1, doi. 10.1007/s00894-022-05355-w

By:

Purohit, Priyanka;
Sahoo, Sthitaprajna;
Panda, Madhusmita;
Sahoo, Partha Sarathi;
Meher, Biswa Ranjan

Publication type:

Article

Macrophage p38 Mitogen-Activated Protein Kinase Activity Regulates Invariant Natural Killer T-Cell Responses During Borrelia burgdorferi Infection.

Published in:

Journal of Infectious Diseases, 2012, v. 206, n. 2, p. 283, doi. 10.1093/infdis/jis332

By:

Hawley, Kelly;
Navasa, Nicolás;
Olson, Chris M.;
Bates, Tonya C.;
Garg, Renu;
Hedrick, Michael N.;
Conze, Dietrich;
Rincón, Mercedes;
Anguita, Juan

Publication type:

Article

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets.

Published in:

Journal of Infectious Diseases, 2012, v. 206, n. 2, p. 229, doi. 10.1093/infdis/jir857

By:

de Koning, Harry P.;
Gould, Matthew K.;
Sterk, Geert Jan;
Tenor, Hermann;
Kunz, Stefan;
Luginbuehl, Edith;
Seebeck, Thomas

Publication type:

Article

Dried Blood Spots on Filter Paper as an Alternative Specimen for Measles Diagnostics: Detection of Measles Immunoglobulin M Antibody by a Commercial Enzyme Immunoassay.

Published in:

Journal of Infectious Diseases, 2011, v. 204, p. S564, doi. 10.1093/infdis/jir088

By:

Uzicanin, Amra;
Lubega, Irene;
Nanuynja, Miriam;
Mercader, Sara;
Rota, Paul;
Bellini, William;
Helfand, Rita

Publication type:

Article

A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses.

Published in:

EMBO Journal, 2010, v. 29, n. 5, p. 943, doi. 10.1038/emboj.2009.400

By:

Lilley, Caroline E.;
Chaurushiya, Mira S.;
Boutell, Chris;
Landry, Sebastien;
Suh, Junghae;
Panier, Stephanie;
Everett, Roger D.;
Stewart, Grant S.;
Durocher, Daniel;
Weitzman, Matthew D.

Publication type:

Article

Phytoconstituents of Artemisia Annua as potential inhibitors of SARS CoV2 main protease: an in silico study.

Published in:

BMC Infectious Diseases, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12879-024-09387-w

By:

Irfan, Eraj;
Dilshad, Erum;
Ahmad, Faisal;
Almajhdi, Fahad Nasser;
Hussain, Tajamul;
Abdi, Gholamreza;
Waheed, Yasir

Publication type:

Article

Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010832

By:

Pringle, Eric S.;
Duguay, Brett A.;
Bui-Marinos, Maxwell P.;
Mulloy, Rory P.;
Landreth, Shelby L.;
Desireddy, Krishna Swaroop;
Dolliver, Stacia M.;
Ying, Shan;
Caddell, Taylor;
Tooley, Trinity H.;
Slaine, Patrick D.;
Bearne, Stephen L.;
Falzarano, Darryl;
Corcoran, Jennifer A.;
Khaperskyy, Denys A.;
McCormick, Craig

Publication type:

Article

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010811

By:

Walter, Marius;
Chen, Irene P.;
Vallejo-Gracia, Albert;
Kim, Ik-Jung;
Bielska, Olga;
Lam, Victor L.;
Hayashi, Jennifer M.;
Cruz, Andrew;
Shah, Samah;
Soveg, Frank W.;
Gross, John D.;
Krogan, Nevan J.;
Jerome, Keith R.;
Schilling, Birgit;
Ott, Melanie;
Verdin, Eric

Publication type:

Article

SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export.

Published in:

PLoS Pathogens, 2022, v. 18, n. 8, p. 1, doi. 10.1371/journal.ppat.1010349

By:

Hall, Ross;
Guedán, Anabel;
Yap, Melvyn W.;
Young, George R.;
Harvey, Ruth;
Stoye, Jonathan P.;
Bishop, Kate N.

Publication type:

Article

Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing.

Published in:

PLoS Pathogens, 2022, p. 1, doi. 10.1371/journal.ppat.1010099

By:

Ly, Michael;
Burgess, Hannah M.;
Shah, Sahil B.;
Mohr, Ian;
Glaunsinger, Britt A.

Publication type:

Article

A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection.

Published in:

PLoS Pathogens, 2022, v. 18, n. 2, p. 1, doi. 10.1371/journal.ppat.1010265

By:

Gerber, Pehuén Pereyra;
Duncan, Lidia M.;
Greenwood, Edward JD;
Marelli, Sara;
Naamati, Adi;
Teixeira-Silva, Ana;
Crozier, Thomas WM;
Gabaev, Ildar;
Zhan, Jun R.;
Mulroney, Thomas E.;
Horner, Emily C.;
Doffinger, Rainer;
Willis, Anne E.;
Thaventhiran, James ED;
Protasio, Anna V.;
Matheson, Nicholas J.

Publication type:

Article

The Epstein-Barr virus deubiquitinating enzyme BPLF1 regulates the activity of topoisomerase II during productive infection.

Published in:

PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009954

By:

Li, Jinlin;
Nagy, Noemi;
Liu, Jiangnan;
Gupta, Soham;
Frisan, Teresa;
Hennig, Thomas;
Cameron, Donald P.;
Baranello, Laura;
Masucci, Maria G.

Publication type:

Article

HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration.

Published in:

PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009484

By:

Guedán, Anabel;
Donaldson, Callum D.;
Caroe, Eve R.;
Cosnefroy, Ophélie;
Taylor, Ian A.;
Bishop, Kate N.

Publication type:

Article

First molecular detection of canine herpesvirus 1 (CaHV-1) in the Eastern Brazilian Amazon.

Published in:

Journal of Veterinary Science, 2022, v. 23, n. 2, p. 1, doi. 10.4142/jvs.21202

By:

Santos Castro, Marcela dos;
Moraes David, Maridelzira Betania;
Gonçalves, Evonnildo Costa;
Siqueira, Andrei Santos;
Virgulino, Rodrigo Rodrigues;
Figueira Aguiar, Delia Cristina

Publication type:

Article

Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 527, doi. 10.1038/nsmb1254

By:

Yu Chen;
Yanhui Xu;
Qing Bao;
Yongna Xing;
Zhu Li;
Zheng Lin;
Stock, Jeffry B.;
Jeffrey, Philip D.;
Yigong Shi

Publication type:

Article

Development of a novel fluorogenic assay method for screening inhibitors of bovine leukemia virus protease and identification of mitorubrinic acid as an anti-BLV compound.

Published in:

Bioscience, Biotechnology & Biochemistry, 2023, v. 87, n. 9, p. 946, doi. 10.1093/bbb/zbad073

By:

Hironobu Murakami;
Yuuta Fujikawa;
Masaya Mori;
Nozomi Mosu;
Akihiro Taguchi;
Yoshio Hayashi;
Hideshi Inoue;
Shinji Kamisuki

Publication type:

Article

Enzymes in the time of COVID‐19: An overview about the effects in the human body, enzyme market, and perspectives for new drugs.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 6, p. 2126, doi. 10.1002/med.21919

By:

Fé, Luana Xavier Soares Gomes Moura;
Cipolatti, Eliane Pereira;
Pinto, Martina Costa Cerqueira;
Branco, Suema;
Nogueira, Fábio César Sousa;
Ortiz, Gisela Maria Dellamora;
Pinheiro, Anderson de Sá;
Manoel, Evelin Andrade

Publication type:

Article

Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors.

Published in:

Medical Microbiology & Immunology, 2012, v. 201, n. 2, p. 213, doi. 10.1007/s00430-011-0224-z

By:

Knops, Elena;
Brakier-Gingras, Léa;
Schülter, Eugen;
Pfister, Herbert;
Kaiser, Rolf;
Verheyen, Jens

Publication type:

Article

Computational Bioprospecting Guggulsterone against ADP Ribose Phosphatase of SARS-CoV-2.

Published in:

Molecules, 2022, v. 27, n. 23, p. 8287, doi. 10.3390/molecules27238287

By:

Kciuk, Mateusz;
Mujwar, Somdutt;
Rani, Isha;
Munjal, Kavita;
Gielecińska, Adrianna;
Kontek, Renata;
Shah, Kamal

Publication type:

Article

Microbicide Containing Ellagic Acid Can Inhibit HIV-1 Infection.

Published in:

Molecules, 2022, v. 27, n. 22, p. 7941, doi. 10.3390/molecules27227941

By:

Nittayananta, Wipawee;
Promsong, Aornrutai;
Levy, Claire;
Hladik, Florian;
Chaitaveep, Nithinart;
Ungphaiboon, Suwipa;
Tewtrakul, Supinya;
Satthakarn, Surada

Publication type:

Article

Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7522, doi. 10.3390/molecules27217522

By:

Romeo, Isabella;
Ambrosio, Francesca Alessandra;
Costa, Giosuè;
Corona, Angela;
Alkhatib, Mohammad;
Salpini, Romina;
Lemme, Saverio;
Vergni, Davide;
Svicher, Valentina;
Santoro, Maria Mercedes;
Tramontano, Enzo;
Ceccherini-Silberstein, Francesca;
Artese, Anna;
Alcaro, Stefano

Publication type:

Article

Synthesis and Applications of Nitrogen-Containing Heterocycles as Antiviral Agents.

Published in:

Molecules, 2022, v. 27, n. 9, p. 2700, doi. 10.3390/molecules27092700

By:

Tran, Tuyen N.;
Henary, Maged

Publication type:

Article

A New Class of Uracil–DNA Glycosylase Inhibitors Active against Human and Vaccinia Virus Enzyme.

Published in:

Molecules, 2021, v. 26, n. 21, p. 6668, doi. 10.3390/molecules26216668

By:

Grin, Inga R.;
Mechetin, Grigory V.;
Kasymov, Rustem D.;
Diatlova, Evgeniia A.;
Yudkina, Anna V.;
Shchelkunov, Sergei N.;
Gileva, Irina P.;
Denisova, Alexandra A.;
Stepanov, Grigoriy A.;
Chilov, Ghermes G.;
Zharkov, Dmitry O.

Publication type:

Article

Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge.

Published in:

Molecules, 2020, v. 25, n. 23, p. 5695, doi. 10.3390/molecules25235695

By:

Picarazzi, Francesca;
Vicenti, Ilaria;
Saladini, Francesco;
Zazzi, Maurizio;
Mori, Mattia;
Carta, Fabrizio;
Angeli, Andrea

Publication type:

Article

Noi metode imagistice în evaluarea pacientului pediatric cu suspiciune de miocardită.

Published in:

Medic.ro, 2021, v. 141, n. 3, p. 42

By:

Gîdea, Rebeca;
Toma, Daniela;
Pop, Marian

Publication type:

Article

Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance.

Published in:

Biomedicines, 2022, v. 10, n. 3, p. 580, doi. 10.3390/biomedicines10030580

By:

Andrei, Graciela;
Fiten, Pierre;
Krečmerová, Marcela;
Opdenakker, Ghislain;
Topalis, Dimitrios;
Snoeck, Robert

Publication type:

Article

Pharmacophore-guided identification of flavonoid compounds as potential inhibitors for 3C protease of enterovirus A71 and coxsackievirus A16.

Published in:

ScienceAsia, 2025, v. 51, n. 1, p. 1, doi. 10.2306/scienceasia1513-1874.2025.018

By:

Rungrotmongkol, Thanyada;
Sripattarphan, Amita;
Sanachai, Kamonpan;
Chavasiri, Warinthorn;
Wolschann, Peter;
Langer, Thierry;
Boonyasuppayakorn, Siwaporn

Publication type:

Article

Identification of the viral RNA promoter stem loop A (SLA)-binding site on Zika virus polymerase NS5.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70094-y

By:

Bujalowski, Paul J.;
Bujalowski, Wlodzimierz;
Choi, Kyung H.

Publication type:

Article

White Spot Syndrome Virus Triggers a Glycolytic Pathway in Shrimp Immune Cells (Hemocytes) to Benefit Its Replication.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.901111

By:

Yen Siong Ng;
Der-Yen Lee;
Chun-Hung Liu;
Cheng-Yi Tung;
Shu-Ting He;
Han-Ching Wang

Publication type:

Article

Remdesivir and Its Combination With Repurposed Drugs as COVID-19 Therapeutics.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.830990

By:

Chatterjee, Bhaswati;
Thakur, Suman S.

Publication type:

Article

In-silico STUDIES OF AMENTOFLAVONE AND ITS DERIVATIVES AGAINST SARS-COV-2.

Published in:

Rasayan Journal of Chemistry, 2021, v. 14, n. 3, p. 1469, doi. 10.31788/RJC.2021.1436172

By:

Ibrahim, Faisal Maulana;
Holik, Holis Abdul;
Achmad, Arifudin

Publication type:

Article

ALADDIN: Docking Approach Augmented by Machine Learning for Protein Structure Selection Yields Superior Virtual Screening Performance.

Published in:

Molecular Informatics, 2020, v. 39, n. 4, p. 1, doi. 10.1002/minf.201900103

By:

Fan, Ningning;
Bauer, Christoph A.;
Stork, Conrad;
Bruyn Kops, Christina;
Kirchmair, Johannes

Publication type:

Article

The Cardiotoxic Effects of Remdesivir Administered to the Patients with SARS-CoV Infection.

Published in:

Journal of Young Pharmacists, 2023, v. 15, n. 4, p. 767, doi. 10.5530/jyp.2023.15.107

By:

Bhagat, Dharti;
Patel, Sefali;
Dikkatwar, Manoj;
Bindu, Radhika

Publication type:

Article

Vesicular Stomatitis Virus Polymerase's Strong Affinity to Its Template Suggests Exotic Transcription Models.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.pcbi.1004004

By:

Tang, Xiaolin;
Bendjennat, Mourad;
Saffarian, Saveez

Publication type:

Article

Target identification for repurposed drugs active against SARS-CoV-2 via high-throughput inverse docking.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 1, p. 25, doi. 10.1007/s10822-021-00432-3

By:

Ribone, Sergio R.;
Paz, S. Alexis;
Abrams, Cameron F.;
Villarreal, Marcos A.

Publication type:

Article

Role of a cotton endoreduplication-related gene, GaTOP6B, in response to drought stress.

Published in:

Planta: An International Journal of Plant Biology, 2019, v. 249, n. 4, p. 1119, doi. 10.1007/s00425-018-3067-7

By:

Tian, Yanfei;
Gu, Huihui;
Fan, Zhuxuan;
Shi, Gongyao;
Yuan, Jiachen;
Wei, Fang;
Yang, Yan;
Tian, Baoming;
Cao, Gangqiang;
Huang, Jinyong

Publication type:

Article

PRBP plays a role in plastid ribosomal RNA maturation and chloroplast biogenesis in Nicotiana benthamiana.

Published in:

Planta: An International Journal of Plant Biology, 2011, v. 233, n. 6, p. 1073, doi. 10.1007/s00425-011-1362-7

By:

Yong-Joon Park;
Hui-Kyung Cho;
Hyun Jung;
Chang Ahn;
Hunseung Kang;
Hyun-Sook Pai

Publication type:

Article