Works matching DE "VIRAL nonstructural proteins"

Results: 507

Piece of the puzzle: Remdesivir disassembles the multimeric SARS-CoV-2 RNA-dependent RNA polymerase complex.

Published in:

Cell Biochemistry & Biophysics, 2021, v. 79, n. 2, p. 175, doi. 10.1007/s12013-021-00977-y

By:

Olotu, Fisayo A.;
Omolabi, Kehinde F.;
Soliman, Mahmoud E. S.

Publication type:

Article

Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C.

Published in:

PLoS Biology, 2020, v. 18, n. 11, p. 1, doi. 10.1371/journal.pbio.3000904

By:

Bauer, Lisa;
Manganaro, Roberto;
Zonsics, Birgit;
Hurdiss, Daniel L.;
Zwaagstra, Marleen;
Donselaar, Tim;
Welter, Naemi G. E.;
van Kleef, Regina G. D. M.;
Lopez, Moira Lorenzo;
Bevilacqua, Federica;
Raman, Thamidur;
Ferla, Salvatore;
Bassetto, Marcella;
Neyts, Johan;
Strating, Jeroen R. P. M.;
Westerink, Remco H. S.;
Brancale, Andrea;
van Kuppeveld, Frank J. M.

Publication type:

Article

Zika virus: what we need to know?

Published in:

Journal of Basic Microbiology, 2018, v. 58, n. 1, p. 3, doi. 10.1002/jobm.201700398

By:

Javed, Farakh;
Manzoor, Khanzadi N.;
Ali, Mubashar;
Haq, Irshad U.;
Khan, Abid A.;
Zaib, Assad;
Manzoor, Sobia

Publication type:

Article

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10.

Published in:

Molecules, 2021, v. 26, n. 20, p. 6151, doi. 10.3390/molecules26206151

By:

Eissa, Ibrahim H.;
Khalifa, Mohamed M.;
Elkaeed, Eslam B.;
Hafez, Elsayed E.;
Alsfouk, Aisha A.;
Metwaly, Ahmed M.

Publication type:

Article

Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico Screening.

Published in:

Molecules, 2021, v. 26, n. 17, p. 5324, doi. 10.3390/molecules26175324

By:

Elkamhawy, Ahmed;
Ammar, Usama M.;
Paik, Sora;
Abdellattif, Magda H.;
Elsherbeny, Mohamed H.;
Lee, Kyeong;
Roh, Eun Joo

Publication type:

Article

Small Interfering RNAs Are Highly Effective Inhibitors of Crimean-Congo Hemorrhagic Fever Virus Replication In Vitro.

Published in:

Molecules, 2020, v. 25, n. 23, p. 5771, doi. 10.3390/molecules25235771

By:

Földes, Fanni;
Madai, Mónika;
Papp, Henrietta;
Kemenesi, Gábor;
Zana, Brigitta;
Geiger, Lili;
Gombos, Katalin;
Somogyi, Balázs;
Bock-Marquette, Ildikó;
Jakab, Ferenc;
Fujinaga, Koh

Publication type:

Article

COVID-19 In Silico Drug with Zingiber officinale Natural Product Compound Library Targeting the M<sup>pro</sup> Protein.

Published in:

Makara Journal of Science, 2021, v. 25, n. 3, p. 162, doi. 10.7454/mss.v25i3.1244

By:

Wijaya, Renadya Maulani;
Hafidzhah, Muhammad Aldino;
Kharisma, Viol Dhea;
Ansori, Arif Nur Muhammad;
Parikesit, Arli Aditya

Publication type:

Article

Detection of the ORF1 Gene Is an Indicator of the Possible Isolation of Severe Acute Respiratory Syndrome Coronavirus 2.

Published in:

Pathogens, 2022, v. 11, n. 3, p. 302, doi. 10.3390/pathogens11030302

By:

Shirato, Kazuya;
Kakizaki, Masatoshi;
Tomita, Yuriko;
Kawase, Miyuki;
Takeda, Makoto

Publication type:

Article

De-Coding the Contributions of the Viral RNAs to Alphaviral Pathogenesis.

Published in:

Pathogens, 2021, v. 10, n. 6, p. 771, doi. 10.3390/pathogens10060771

By:

LaPointe, Autumn T.;
Sokoloski, Kevin J.

Publication type:

Article

The Tip Region on VP2 Protein of Bluetongue Virus Contains Potential IL-4-Inducing Amino Acid Peptide Segments.

Published in:

Pathogens, 2021, v. 10, n. 1, p. 3, doi. 10.3390/pathogens10010003

By:

Yang, Jia-Ling;
Chang, Chia-Yi;
Sheng, Chih-Shuan;
Wang, Chia-Chi;
Wang, Fun-In

Publication type:

Article

The Infectious Pancreatic Necrosis Virus (IPNV) and its Virulence Determinants: What is Known and What Should be Known.

Published in:

Pathogens, 2020, v. 9, n. 2, p. 94, doi. 10.3390/pathogens9020094

By:

Dopazo, Carlos P.

Publication type:

Article

Development of a Multivalent Kunjin Virus Reporter Virus-Like Particle System Inducing Seroconversion for Ebola and West Nile Virus Proteins in Mice.

Published in:

Microorganisms, 2020, v. 8, n. 12, p. 1890, doi. 10.3390/microorganisms8121890

By:

Tran, Pham-Tue-Hung;
Asghar, Naveed;
Höglund, Urban;
Larsson, Olivia;
Haag, Lars;
Mirazimi, Ali;
Johansson, Magnus;
Melik, Wessam

Publication type:

Article

Four New Genes of Cyanobacterium Synechococcus elongatus PCC 7942 Are Responsible for Sensitivity to 2-Nonanone.

Published in:

Microorganisms, 2020, v. 8, n. 8, p. 1234, doi. 10.3390/microorganisms8081234

By:

Koksharova, Olga A.;
Popova, Alexandra A.;
Plyuta, Vladimir A.;
Khmel, Inessa A.

Publication type:

Article

Glycyrrhizin Inhibits SARS-CoV-2 Entry into Cells by Targeting ACE2.

Published in:

Life (2075-1729), 2022, v. 12, n. 11, p. 1706, doi. 10.3390/life12111706

By:

He, Ming-Feng;
Liang, Jian-Hui;
Shen, Yan-Ni;
Zhang, Jin-Wen;
Liu, Ying;
Yang, Kuang-Yang;
Liu, Li-Chu;
Wang, Junyi;
Xie, Qian;
Hu, Chun;
Song, Xun;
Wang, Yan

Publication type:

Article

Review of Ribosome Interactions with SARS-CoV-2 and COVID-19 mRNA Vaccine.

Published in:

Life (2075-1729), 2022, v. 12, n. 1, p. 57, doi. 10.3390/life12010057

By:

Wei, Jiao;
Hui, Aimin

Publication type:

Article

Structural and Drug Screening Analysis of the Non-structural Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 Virus Extracted From Indian Coronavirus Disease 2019 Patients.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.626642

By:

Biswas, Nupur;
Kumar, Krishna;
Mallick, Priyanka;
Das, Subhrangshu;
Kamal, Izaz Monir;
Bose, Sarpita;
Choudhury, Anindita;
Chakrabarti, Saikat

Publication type:

Article

Heat shock protein 70 enhances viral replication by stabilizing Senecavirus A nonstructural proteins L and 3D.

Published in:

Veterinary Research, 2024, v. 55, n. 1, p. 1, doi. 10.1186/s13567-024-01414-7

By:

Hou, Lei;
Zeng, Penghui;
Wu, Zhi;
Yang, Xiaoyu;
Guo, Jinshuo;
Shi, Yongyan;
Song, Jiangwei;
Zhou, Jianwei;
Liu, Jue

Publication type:

Article

Porcine deltacoronavirus nonstructural protein 2 inhibits type I and III IFN production by targeting STING for degradation.

Published in:

Veterinary Research, 2024, v. 55, n. 1, p. 1, doi. 10.1186/s13567-024-01330-w

By:

Liu, Xiqian;
Ji, Likai;
Cheng, Yuqiang;
Kong, Linghe;
Xie, Songhua;
Yang, Juan;
Chen, Jiaqi;
Wang, Zhaofei;
Ma, Jingjiao;
Wang, Hengan;
Yan, Yaxian;
Sun, Jianhe

Publication type:

Article

ZNF283, a Krüppel-associated box zinc finger protein, inhibits RNA synthesis of porcine reproductive and respiratory syndrome virus by interacting with Nsp9 and Nsp10.

Published in:

Veterinary Research, 2024, v. 55, n. 1, p. 1, doi. 10.1186/s13567-023-01263-w

By:

Yi, Heyou;
Ye, Ruirui;
Xie, Ermin;
Lu, Lechen;
Wang, Qiumei;
Wang, Shaojun;
Sun, Yankuo;
Tian, Tao;
Qiu, Yingwu;
Wu, Qianwen;
Zhang, Guihong;
Wang, Heng

Publication type:

Article

Interleukin-22 facilitates the interferon-λ-mediated production of tripartite motif protein 25 to inhibit replication of duck viral hepatitis A virus type 1.

Published in:

Veterinary Research, 2023, v. 54, n. 1, p. 1, doi. 10.1186/s13567-023-01188-4

By:

An, Hao;
Liu, Yumei;
Shu, Ming;
Chen, Junhao

Publication type:

Article

Nonstructural proteins 2B and 4A of Tembusu virus induce complete autophagy to promote viral multiplication in vitro.

Published in:

Veterinary Research, 2023, v. 54, n. 1, p. 1, doi. 10.1186/s13567-023-01152-2

By:

Tan, Wangyang;
Zhang, Senzhao;
He, Yu;
Wu, Zhen;
Wang, Mingshu;
Jia, Renyong;
Zhu, Dekang;
Liu, Mafeng;
Zhao, Xinxin;
Yang, Qiao;
Wu, Ying;
Zhang, Shaqiu;
Huang, Juan;
Mao, Sai;
Ou, Xumin;
Gao, Qun;
Sun, Di;
Tian, Bin;
Chen, Shun;
Cheng, Anchun

Publication type:

Article

Suppressors of silencers: Exploring viral suppression of RNAi in emerging RNA viruses.

Published in:

Journal of Microbiology & Infectious Diseases, 2023, v. 13, n. 3, p. 110, doi. 10.5455/JMID.2023.v13.i3.2

By:

Syed Ali, P. Shaik

Publication type:

Article

Evolution of STAT2 resistance to flavivirus NS5 occurred multiple times despite genetic constraints.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49758-0

By:

Veit, Ethan C.;
Salim, Madihah S.;
Jung, Mariel J.;
Richardson, R. Blake;
Boys, Ian N.;
Quinlan, Meghan;
Barrall, Erika A.;
Bednarski, Eva;
Hamilton, Rachael E.;
Kikawa, Caroline;
Elde, Nels C.;
García-Sastre, Adolfo;
Evans, Matthew J.

Publication type:

Article

TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00872-w

By:

Zu, Shulong;
Li, Chunfeng;
Li, Lili;
Deng, Yong-Qiang;
Chen, Xiang;
Luo, Dan;
Ye, Qing;
Huang, Yi-Jiao;
Li, Xiao-Feng;
Zhang, Rong-Rong;
Sun, Nina;
Zhang, Xianqi;
Aliyari, Saba R.;
Nielsen-Saines, Karin;
Jung, Jae U.;
Yang, Heng;
Qin, Cheng-Feng;
Cheng, Genhong

Publication type:

Article

Structure and Function of Major SARS-CoV-2 and SARS-CoV Proteins.

Published in:

Bioinformatics & Biology Insights, 2021, p. 1, doi. 10.1177/11779322211025876

By:

Gorkhali, Ritesh;
Koirala, Prashanna;
Rijal, Sadikshya;
Mainali, Ashmita;
Baral, Adesh;
Bhattarai, Hitesh Kumar

Publication type:

Article

Structure and Function of Major SARS-CoV-2 and SARS-CoV Proteins.

Published in:

Bioinformatics & Biology Insights, 2021, v. 15, p. 1, doi. 10.1177/11779322211025876

By:

Gorkhali, Ritesh;
Koirala, Prashanna;
Rijal, Sadikshya;
Mainali, Ashmita;
Baral, Adesh;
Bhattarai, Hitesh Kumar

Publication type:

Article

HIV-1 Vpu and SARS-CoV-2 ORF3a proteins disrupt STING-mediated activation of antiviral NF-κB signaling.

Published in:

Science Signaling, 2025, v. 18, n. 870, p. 1, doi. 10.1126/scisignal.add6593

By:

Rui, Yajuan;
Shen, Si;
Wang, Yanpu;
Cheng, Leyi;
Chen, Shiqi;
Hu, Ying;
Cai, Yong;
Wei, Wei;
Su, Jiaming;
Yu, Xiao-Fang

Publication type:

Article

Evaluation of the Diagnostic Accuracy of a New Dengue IgA Capture Assay (Platelia Dengue IgA Capture, Bio-Rad) for Dengue Infection Detection.

Published in:

PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003596

By:

De Decker, Sophie;
Vray, Muriel;
Sistek, Viridiana;
Labeau, Bhety;
Enfissi, Antoine;
Rousset, Dominique;
Matheus, Séverine

Publication type:

Article

Expression of NS3/NS4A Proteins of Hepatitis C Virus in Huh7 Cells Following Engineering Its Eukaryotic Expression Vector.

Published in:

Jundishapur Journal of Microbiology, 2015, v. 8, n. 11, p. 1, doi. 10.5812/jjm.27355

By:

Behzadi, Mohammad Amin;
Alborzi, Abdolvahab;
Pouladfar, Gholamreza;
Dianatpour, Mehdi;
Ziyaeyan, Mazyar

Publication type:

Article

A localized surface plasmon resonance-amplified immunofluorescence biosensor for ultrasensitive and rapid detection of nonstructural protein 1 of Zika virus.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0211517

By:

Takemura, Kenshin;
Adegoke, Oluwasesan;
Suzuki, Tetsuro;
Park, Enoch Y.

Publication type:

Article

Outcomes for Cirrhotic Patients with Hepatitis C Virus 1b Treated with Asunaprevir and Daclatasvir Combination.

Published in:

Annals of Hepatology: Official Journal of the Mexican Association of Hepatology, 2017, v. 16, n. 5, p. 734, doi. 10.5604/01.3001.0010.2732

By:

Akihiro Tamori;
Hoang Hai;
Sawako Uchida-Kobayashi;
Masaru Enomoto;
Ritsuzo Kozuka;
Hiroyuki Motoyama;
Etsushi Kawamura;
Atsushi Hagihara;
Yuga Teranishi;
Kanako Yoshida;
Hiroyasu Morikawa;
Yoshiki Murakami;
Norifumi Kawada

Publication type:

Article

Epigenetic mechanisms influencing COVID-19.

Published in:

Genome, 2021, v. 64, n. 4, p. 372, doi. 10.1139/gen-2020-0135

By:

Sen, Rwik;
Garbati, Michael;
Bryant, Kevin;
Lu, Yanan

Publication type:

Article

In vitro antiviral activity of Lactobacillus casei and Bifidobacterium adolescentis against rotavirus infection monitored by NSP4 protein production.

Published in:

Journal of Applied Microbiology, 2016, v. 120, n. 4, p. 1041, doi. 10.1111/jam.13069

By:

Olaya Galán, N.N.;
Ulloa Rubiano, J.C.;
Velez Reyes, F.A.;
Fernandez Duarte, K.P.;
Salas Cárdenas, S.P.;
Gutierrez Fernandez, M.F.

Publication type:

Article

Seasonal nonstructural carbohydrate patterns in dewberry (Rubus spp.) roots.

Published in:

Weed Science, 2021, v. 69, n. 2, p. 186, doi. 10.1017/wsc.2020.96

By:

Ghantous, Katherine M.;
Sandler, Hilary A.

Publication type:

Article

Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.

Published in:

Lipids in Health & Disease, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12944-019-1136-y

By:

Meng, Ziyu;
Liu, Qiang;
Sun, Fujun;
Qiao, Ling

Publication type:

Article

Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells.

Published in:

Acta Pharmacologica Sinica, 2015, v. 36, n. 9, p. 1126, doi. 10.1038/aps.2015.56

By:

Wu, Deng-wei;
Mao, Fei;
Ye, Yan;
Li, Jian;
Xu, Chuan-lian;
Luo, Xiao-min;
Chen, Jing;
Shen, Xu

Publication type:

Article

Decoding mechanisms of diarrhea induction by enteric viruses.

Published in:

PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012414

By:

Hou, Gaopeng;
Ding, Siyuan

Publication type:

Article

The astrovirus N-terminal nonstructural protein anchors replication complexes to the perinuclear ER membranes.

Published in:

PLoS Pathogens, 2024, v. 20, n. 7, p. 1, doi. 10.1371/journal.ppat.1011959

By:

Ali, Hashim;
Noyvert, David;
Hankinson, Jacqueline;
Lindsey, Gemma;
Lulla, Aleksei;
Lulla, Valeria

Publication type:

Article

Human coronavirus NL63 nsp1 induces degradation of RNA polymerase II to inhibit host protein synthesis.

Published in:

PLoS Pathogens, 2024, v. 20, n. 6, p. 1, doi. 10.1371/journal.ppat.1012329

By:

Hardy, Kala;
Lutz, Michael;
Takimoto, Toru

Publication type:

Article

The inflammasome pathway is activated by dengue virus non-structural protein 1 and is protective during dengue virus infection.

Published in:

PLoS Pathogens, 2024, v. 20, n. 4, p. 1, doi. 10.1371/journal.ppat.1012167

By:

Wong, Marcus P.;
Juan, Evan Y. W.;
Pahmeier, Felix;
Chelluri, Sai S.;
Wang, Phoebe;
Castillo-Rojas, Bryan;
Blanc, Sophie F.;
Biering, Scott B.;
Vance, Russell E.;
Harris, Eva

Publication type:

Article

The non-template functions of helper virus RNAs create optimal replication conditions to enhance the proliferation of satellite RNAs.

Published in:

PLoS Pathogens, 2024, v. 20, n. 4, p. 1, doi. 10.1371/journal.ppat.1012174

By:

Qiao, Zimu;
Wang, Jin;
Huang, Kaiyun;
Hu, Honghao;
Gu, Zhouhang;
Liao, Qiansheng;
Du, Zhiyou

Publication type:

Article

Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions.

Published in:

PLoS Pathogens, 2024, v. 20, n. 3, p. 1, doi. 10.1371/journal.ppat.1011830

By:

Layish, Bailey;
Goli, Ram;
Flick, Haley;
Huang, Szu-Wei;
Zhang, Robert Z.;
Kvaratskhelia, Mamuka;
Kane, Melissa

Publication type:

Article

Polyubiquitylated rice stripe virus NS3 translocates to the nucleus to promote cytosolic virus replication via miRNA-induced fibrillin 2 upregulation.

Published in:

PLoS Pathogens, 2024, v. 20, n. 3, p. 1, doi. 10.1371/journal.ppat.1012112

By:

Zhang, Lu;
Li, Yao;
Kuhn, Jens H.;
Zhang, Kun;
Song, Qisheng;
Liu, Fang

Publication type:

Article

Subversion of selective autophagy for the biogenesis of tombusvirus replication organelles inhibits autophagy.

Published in:

PLoS Pathogens, 2024, v. 20, n. 3, p. 1, doi. 10.1371/journal.ppat.1012085

By:

Kang, Yuanrong;
Lin, Wenwu;
Nagy, Peter D.

Publication type:

Article

Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.

Published in:

PLoS Pathogens, 2023, v. 19, n. 12, p. 1, doi. 10.1371/journal.ppat.1011872

By:

Bailey-Elkin, Ben A.;
Knaap, Robert C. M.;
De Silva, Anuradha;
Boekhoud, Ilse M.;
Mous, Sandra;
van Vught, Niek;
Khajehpour, Mazdak;
van den Born, Erwin;
Kikkert, Marjolein;
Mark, Brian L.

Publication type:

Article

Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection.

Published in:

PLoS Pathogens, 2023, v. 19, n. 10, p. 1, doi. 10.1371/journal.ppat.1011697

By:

Dravid, Piyush;
Murthy, Satyapramod;
Attia, Zayed;
Cassady, Cole;
Chandra, Rahul;
Trivedi, Sheetal;
Vyas, Ashish;
Gridly, John;
Holland, Brantley;
Kumari, Anuradha;
Grakoui, Arash;
Cullen, John M.;
Walker, Christopher M.;
Sharma, Himanshu;
Kapoor, Amit

Publication type:

Article

Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3.

Published in:

PLoS Pathogens, 2023, v. 19, n. 10, p. 1, doi. 10.1371/journal.ppat.1011702

By:

Wu, Yang;
Li, Mingwei;
Tian, Jin;
Yan, Haoxin;
Pan, Yudi;
Shi, Hongyan;
Shi, Da;
Chen, Jianfei;
Guo, Longjun;
Feng, Li

Publication type:

Article

The dengue virus NS1 protein; new roles in pathogenesis due to similarities with and affinity for the high-density lipoprotein (HDL)?

Published in:

PLoS Pathogens, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.ppat.1011587

By:

Alcalá, Ana C.;
Ludert, Juan E.

Publication type:

Article

The circRNA circVAMP3 restricts influenza A virus replication by interfering with NP and NS1 proteins.

Published in:

PLoS Pathogens, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.ppat.1011577

By:

Min, Jie;
Li, Yucen;
Li, Xinda;
Wang, Mingge;
Li, Huizi;
Bi, Yuhai;
Xu, Ping;
Liu, Wenjun;
Ye, Xin;
Li, Jing

Publication type:

Article

Hepatitis C virus non-structural proteins modulate cellular kinases for increased cytoplasmic abundance of host factor HuR and facilitate viral replication.

Published in:

PLoS Pathogens, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.ppat.1011552

By:

Raheja, Harsha;
George, Biju;
Tripathi, Sachin Kumar;
Saha, Sandhini;
Maiti, Tushar Kanti;
Das, Saumitra

Publication type:

Article