Works about VIMPAT

Results: 276

Comparison of lacosamide, levetiracetam, and valproate as second‐line therapy in adult status epilepticus: Analysis of a large cohort.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 5, p. e73, doi. 10.1111/epi.18380

By:

Hahn, Cecil D.;
Novy, Jan;
Rossetti, Andrea O.

Publication type:

Article

A fully validated method for the determination of lacosamide in human plasma using gas chromatography with mass spectrometry: Application for therapeutic drug monitoring.

Published in:

Journal of Separation Science, 2015, v. 38, n. 2, p. 260, doi. 10.1002/jssc.201400858

By:

Nikolaou, Panagiota;
Papoutsis, Ioannis;
Spiliopoulou, Chara;
Voudris, Constantinos;
Athanaselis, Sotiris

Publication type:

Article

Lacosamide in patients with gliomas and uncontrolled seizures: results from an observational study.

Published in:

Journal of Neuro-Oncology, 2018, v. 136, n. 1, p. 105, doi. 10.1007/s11060-017-2628-0

By:

Rudà, Roberta;
Pellerino, Alessia;
Franchino, Federica;
Bertolotti, Cinzia;
Bruno, Francesco;
Mo, Francesca;
Migliore, Enrica;
Ciccone, Gianni;
Soffietti, Riccardo

Publication type:

Article

Valproic Acid-Induced Liver Injury: A Case-Control Study from a Prospective Pharmacovigilance Program in a Tertiary Hospital.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 6, p. 1153, doi. 10.3390/jcm10061153

By:

Meseguer, Enrique S.;
Elizalde, Mikel U.;
Borobia, Alberto M.;
Ramírez, Elena;
Van Den Anker, Johannes;
Carcas-Sansuán, Antonio J.;
Borobia Pérez, Alberto M.

Publication type:

Article

Is there a role for pregabalin as premedication in pediatric anesthesia?

Published in:

2021

By:

Nghiem, Jessica;
Brown, Stephen C.;
Aoyama, Kazuyoshi

Publication type:

Editorial

Acute Liver Failure Associated with Levetiracetam and Lacosamide Combination Treatment for Unspecified Epileptic Disorder.

Published in:

Case Reports in Emergency Medicine, 2013, p. 1, doi. 10.1155/2013/634174

By:

Gutiérrez-Grobe, Ylse;
Bahena-Gonzalez, Jose Antonio;
Herrera-Gomar, Magali;
Mendoza-Diaz, Pedro;
García-López, Sandra;
González-Chon, Octavio

Publication type:

Article

Case Report: A Case of Concomitant Paroxysmal Kinesigenic Dyskinesia and Epilepsy: Can We Treat Two Birds With One Stone?

Published in:

Frontiers in Neurology, 2022, v. 12, p. 1, doi. 10.3389/fneur.2022.826897

By:

Geng, Jun-Hong;
Zheng, Yang;
Li, Quan-Fu;
Hou, Qun;
Wang, Xiao-Hang;
Jiang, Yan

Publication type:

Article

Clinical Efficacy and Safety of Lacosamide as an Adjunctive Treatment in Adults With Refractory Epilepsy.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.712717

By:

Hou, Liyan;
Peng, Bingjie;
Zhang, Defu;
Yang, Jingjing;
Wang, Ying;
Tong, Li;
Li, Sheng;
Wang, Qingshan;
Zhao, Jie

Publication type:

Article

Effect of lacosamide on absence seizure development in genetic absence epilepsy rat model.

Published in:

2018

By:

Karanfil, Ceren;
Onat, Filiz;
Çarçak, Nihan

Publication type:

Abstract

Effectiveness and Adverse Effect of Intravenous Lacosamide in Nonconvulsive Status Epilepticus and Acute Repetitive Seizures in Children.

Published in:

Neurology Research International, 2018, p. 1, doi. 10.1155/2018/8432859

By:

Ngampoopun, Monsicha;
Suwanpakdee, Piradee;
Jaisupa, Nattapon;
Nabangchang, Charcrin

Publication type:

Article

A Clinical-EEG Study of Sleepiness and Psychological Symptoms in Pharmacoresistant Epilepsy Patients Treated with Lacosamide.

Published in:

Epilepsy Research & Treatment, 2013, p. 1, doi. 10.1155/2013/593149

By:

Giorgi, Filippo S.;
Pizzanelli, Chiara;
Pelliccia, Veronica;
Coscio, Elisa Di;
Maestri, Michelangelo;
Guida, Melania;
Iacopini, Elena;
Iudice, Alfonso;
Bonanni, Enrica

Publication type:

Article

Lacosamide in children with drug-resistant epilepsy.

Published in:

2019

By:

Rüegger, Andrea D;
Freeman, Jeremy L;
Harvey, A Simon

Publication type:

journal article

Lacosamide as adjunctive therapy in treatment-resistant epilepsy in childhood.

Published in:

Journal of Paediatrics & Child Health, 2015, v. 51, n. 8, p. 794, doi. 10.1111/jpc.12850

By:

Gulati, Pratima;
Cannell, Patricia;
Ghia, Twinkle;
Bint, Lewis;
Walsh, Peter;
Ghosh, Soumya;
Nagarajan, Lakshmi

Publication type:

Article

The Impact of Prophylactic Lacosamide on LPS-Induced Neuroinflammation in Aged Rats.

Published in:

Inflammation, 2019, v. 42, n. 5, p. 1913, doi. 10.1007/s10753-019-01053-7

By:

Savran, Mehtap;
Ozmen, O.;
Erzurumlu, Y.;
Savas, H. B.;
Asci, S.;
Kaynak, M.

Publication type:

Article

Brain Somatic Variant in Ras-Like Small GTPase RALA Causes Focal Cortical Dysplasia Type II.

Published in:

Frontiers in Behavioral Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnbeh.2022.919485

By:

Xu, Han;
Gao, Kai;
Liu, Qingzhu;
Wang, Tianshuang;
Zhang, Zhongbin;
Cai, Lixin;
Wu, Ye;
Jiang, Yuwu

Publication type:

Article

IDENTIFICATION AND CHARACTERIZATION OF DEGRADATION PRODUCTS OF LACOSAMIDE BY LIQUID-CHROMATOGRAPHY/TIME-OF-FLIGHT MASS SPECTROMETRIC AND MULTI-STAGE MASS SPECTROMETRIC ANALYSIS.

Published in:

Journal of Liquid Chromatography & Related Technologies, 2014, v. 37, n. 14, p. 2046, doi. 10.1080/10826076.2013.825860

By:

Tiwari, RaviN.;
Bonde, ChandrakantG.

Publication type:

Article

Neuroprotective effect of lacosamide on cognitive dysfunction in Streptozotocin induced Alzheimer disease.

Published in:

QJM: An International Journal of Medicine, 2021, v. 114, p. i307, doi. 10.1093/qjmed/hcab114

By:

Ibrahim, Fatma Sobhy;
Abdel-Aziz, Lobna Fouad;
Elbakly, Wesam Mostafa;
El Gayar, Nesreen Hamdy

Publication type:

Article

Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report.

Published in:

Clinical Toxicology (15563650), 2015, v. 53, n. 6, p. 565, doi. 10.3109/15563650.2015.1040157

By:

Chua-Tuan, Jenny L.;
Cao, Dazhe;
Iwanicki, Janetta L.;
Hoyte, Christopher O.

Publication type:

Article

Fatal lacosamide poisoning in relation to cardiac conduction impairment and cardiovascular failure.

Published in:

Clinical Toxicology (15563650), 2013, v. 51, n. 4, p. 381, doi. 10.3109/15563650.2013.778993

By:

Malissin, Isabelle;
Baud, Frédéric J.;
Deveaux, Marc;
Champion, Sébastien;
Deye, Nicolas;
Megarbane, Bruno

Publication type:

Article

Potassium citrate and metabolic acidosis in children with epilepsy on the ketogenic diet: a prospective controlled study.

Published in:

2020

By:

Bjurulf, Björn;
Magnus, Per;
Hallböök, Tove;
Strømme, Petter

Publication type:

journal article

Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 5, p. 1008, doi. 10.1002/cpt.2694

By:

Ruijs, Titia Q.;
Koopmans, Ingrid W.;
de Kam, Marieke L.;
van Esdonk, Michiel J.;
Koltzenburg, Martin;
Groeneveld, Geert Jan;
Heuberger, Jules A.A.C.

Publication type:

Article

Prediction of lacosamide concentrations to support dose optimization during pregnancy.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 2, p. 346, doi. 10.1111/epi.18184

By:

Barry, Jessica M.;
Illamola, Sílvia M.;
Pennell, Page B.;
Sherwin, Catherine M.;
Meador, Kimford J.;
Birnbaum, Angela K.

Publication type:

Article

Acetazolamide as an effective treatment for pilomotor seizures in autoimmune encephalitis.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 5, p. e67, doi. 10.1111/epi.17962

By:

Gilani, Kia;
Tarazi, Apameh;
Wennberg, Richard

Publication type:

Article

Lacosamide and pregnancy: Data from spontaneous and solicited reports.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 5, p. 1275, doi. 10.1111/epi.17924

By:

Perucca, Piero;
Bourikas, Dimitrios;
Voinescu, P. Emanuela;
Vadlamudi, Lata;
Chellun, Daya;
Kumke, Thomas;
Werhahn, Konrad J.;
Schmitz, Bettina

Publication type:

Article

Value of drug level concentrations of brivaracetam, lacosamide, and perampanel in care of people with epilepsy.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 3, p. 620, doi. 10.1111/epi.17873

By:

Hentschel, Matthias;
Stoffel‐Wagner, Birgit;
Surges, Rainer;
von Wrede, Randi;
Dolscheid‐Pommerich, Ramona Christina

Publication type:

Article

Long‐term treatment with ganaxolone for seizures associated with cyclin‐dependent kinase‐like 5 deficiency disorder: Two‐year open‐label extension follow‐up.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 1, p. 37, doi. 10.1111/epi.17826

By:

Olson, Heather E.;
Amin, Sam;
Bahi‐Buisson, Nadia;
Devinsky, Orrin;
Marsh, Eric D.;
Pestana‐Knight, Elia;
Rajaraman, Rajsekar R.;
Aimetti, Alex A.;
Rybak, Eva;
Kong, Fanhui;
Miller, Ian;
Hulihan, Joseph;
Demarest, Scott

Publication type:

Article

Safety, tolerability, and efficacy of adjunctive lacosamide in pediatric patients with epilepsy syndromes associated with generalized seizures: Phase 2, open‐label exploratory trial.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 11, p. 2947, doi. 10.1111/epi.17741

By:

Auvin, Stéphane;
Arzimanoglou, Alexis;
Beller, Cynthia;
Floricel, Florin;
Daniels, Tony;
Bozorg, Ali

Publication type:

Article

Short‐ and long‐interval intracortical inhibition in EPM1 is related to genotype.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 1, p. 208, doi. 10.1111/epi.17466

By:

Silvennoinen, Katri;
Säisänen, Laura;
Hyppönen, Jelena;
Rissanen, Saara M.;
Karjalainen, Pasi A.;
D'Ambrosio, Sasha;
Jimenez‐Jimenez, Diego;
Zagaglia, Sara;
Rothwell, John C.;
Balestrini, Simona;
Sisodiya, Sanjay M.;
Julkunen, Petro;
Mervaala, Esa;
Kälviäinen, Reetta

Publication type:

Article

Lacosamide decreases neonatal seizures without increasing apoptosis.

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 12, p. 3051, doi. 10.1111/epi.17423

By:

Langton, Rachel L.;
Sharma, Shaunik;
Tiarks, Grant C.;
Bassuk, Alexander G.;
Glykys, Joseph

Publication type:

Article

Lacosamide effects on placental carriers of essential compounds in comparison with valproate: Studies in perfused human placentas.

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 11, p. 2949, doi. 10.1111/epi.17395

By:

Berman, Erez;
Kohn, Elkana;
Berkovitch, Matitiahu;
Kovo, Michal;
Eyal, Sara

Publication type:

Article

Therapeutic drug monitoring of fenfluramine in clinical practice: Pharmacokinetic variability and impact of concomitant antiseizure medications.

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 3, p. 686, doi. 10.1111/epi.17162

By:

Schoonjans, An‐Sofie;
Roosens, Laurence;
Dewals, Wendy;
Paelinck, Bernard P.;
Ceulemans, Berten

Publication type:

Article

OV329, a novel highly potent γ‐aminobutyric acid aminotransferase inactivator, induces pronounced anticonvulsant effects in the pentylenetetrazole seizure threshold test and in amygdala‐kindled rats.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 12, p. 3091, doi. 10.1111/epi.17090

By:

Feja, Malte;
Meller, Sebastian;
Deking, Lillian S.;
Kaczmarek, Edith;
During, Matthew J.;
Silverman, Richard B.;
Gernert, Manuela

Publication type:

Article

Small loci of astroglial glutamine synthetase deficiency in the postnatal brain cause epileptic seizures and impaired functional connectivity.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 11, p. 2858, doi. 10.1111/epi.17072

By:

Farina, Maxwell G.;
Sandhu, Mani Ratnesh S.;
Parent, Maxime;
Sanganahalli, Basavaraju G.;
Derbin, Matthew;
Dhaher, Roni;
Wang, Helen;
Zaveri, Hitten P.;
Zhou, Yun;
Danbolt, Niels C.;
Hyder, Fahmeed;
Eid, Tore

Publication type:

Article

Neurodevelopmental outcomes in children exposed to newer antiseizure medications: A systematic review.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 8, p. 1765, doi. 10.1111/epi.16953

By:

Knight, Rebecca;
Wittkowski, Anja;
Bromley, Rebecca Louise

Publication type:

Article

Impact of carbamazepine and lacosamide on serum lipid levels.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 4, p. 1034, doi. 10.1111/epi.16859

By:

Panda, Prateek Kumar;
Sharawat, Indar Kumar

Publication type:

Article

Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 3, p. 659, doi. 10.1111/epi.16840

By:

Goossens, Marie‐Gabrielle;
Boon, Paul;
Wadman, Wytse;
Van den Haute, Chris;
Baekelandt, Veerle;
Verstraete, Alain G.;
Vonck, Kristl;
Larsen, Lars E.;
Sprengers, Mathieu;
Carrette, Evelien;
Desloovere, Jana;
Meurs, Alfred;
Delbeke, Jean;
Vanhove, Christian;
Raedt, Robrecht

Publication type:

Article

Effects of lacosamide and carbamazepine on lipids in a randomized trial.

Published in:

Epilepsia (Series 4), 2020, v. 61, n. 12, p. 2696, doi. 10.1111/epi.16745

By:

Mintzer, Scott;
Dimova, Svetlana;
Zhang, Ying;
Steiniger‐Brach, Björn;
De Backer, Marc;
Chellun, Daya;
Roebling, Robert

Publication type:

Article

Long‐term safety and efficacy of lacosamide and controlled‐release carbamazepine monotherapy in patients with newly diagnosed epilepsy.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 12, p. 2437, doi. 10.1111/epi.16381

By:

Ben‐Menachem, Elinor;
Grebe, Hans Peter;
Terada, Kiyohito;
Jensen, Lori;
Li, Ting;
De Backer, Marc;
Steiniger‐Brach, Björn;
Gasalla, Teresa;
Brock, Melissa;
Biton, Victor

Publication type:

Article

Sulfasalazine decreases mouse cortical hyperexcitability.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 7, p. 1365, doi. 10.1111/epi.16073

By:

Alcoreza, Oscar;
Tewari, Bhanu P.;
Bouslog, Allison;
Savoia, Andrew;
Sontheimer, Harald;
Campbell, Susan L.

Publication type:

Article

Long‐term efficacy of add‐on lacosamide treatment in children and adolescents with refractory epilepsies: A single‐center observational study.

Published in:

Epilepsia (Series 4), 2018, v. 59, n. 5, p. 1004, doi. 10.1111/epi.14071

By:

Rosati, Anna;
Ilvento, Lucrezia;
Rizzi, Riccardo;
Doccini, Viola;
Leo, Maria Carmela;
Pugi, Alessandra;
De Masi, Salvatore;
Guerrini, Renzo

Publication type:

Article

Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled‐release carbamazepine in noninferiority epilepsy monotherapy trials: How much “fair” is “fair”?

Published in:

2018

By:

Brigo, Francesco;
Lattanzi, Simona

Publication type:

Letter to the Editor

Assessment of the correlations of lacosamide concentrations in saliva and serum in patients with epilepsy.

Published in:

Epilepsia (Series 4), 2018, v. 59, n. 4, p. e34, doi. 10.1111/epi.14023

By:

Brandt, Christian;
Bien, Christian G.;
Helmer, Renate;
May, Theodor W.

Publication type:

Article

Issue Information–ISSN page.

Published in:: Epilepsia (Series 4), 2018, v. 59, n. 4, p. i, doi. 10.1111/epi.13879
Publication type:: Article

Lacosamide in the treatment of patients with epilepsy and intellectual disabilities: A long-term study of 136 patients.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 10, p. 1749, doi. 10.1111/epi.13869

By:

Böttcher, Stefan;
Lutz, Martin T.;
Mayer, Thomas

Publication type:

Article

Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 10, p. 1755, doi. 10.1111/epi.13856

By:

Nemes, Ashley D.;
O'Dwyer, Rebecca;
Najm, Imad M.;
Ying, Zhong;
Gonzalez‐Martinez, Jorge;
Alexopoulos, Andreas V.

Publication type:

Article

Lacosamide in status epilepticus: Systematic review of current evidence.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 6, p. 933, doi. 10.1111/epi.13716

By:

Strzelczyk, Adam;
Zöllner, Johann Philipp;
Willems, Laurent M.;
Jost, Julie;
Paule, Esther;
Schubert‐Bast, Susanne;
Rosenow, Felix;
Bauer, Sebastian

Publication type:

Article

Retracted: A randomized controlled trial of lacosamide versus sodium valproate in status epilepticus.

Published in:: Epilepsia (Series 4), 2017, v. 58, n. 5, p. 919, doi. 10.1111/epi.13706
Publication type:: Article

Randomized controlled trials in status epilepticus: Size matters.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 5, p. 915, doi. 10.1111/epi.13775

By:

Brigo, Francesco;
Trinka, Eugen

Publication type:

Article

Activity of the anticonvulsant lacosamide in experimental and human epilepsy via selective effects on slow Na<sup>+</sup> channel inactivation.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 1, p. 27, doi. 10.1111/epi.13602

By:

Holtkamp, Dominik;
Opitz, Thoralf;
Niespodziany, Isabelle;
Wolff, Christian;
Beck, Heinz

Publication type:

Article

Abstracts.

Published in:: Epilepsia (Series 4), 2016, v. 57, p. 6, doi. 10.1111/epi.13609
Publication type:: Article