Works about UNFOLDED protein response

Results: 1541
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    Patient-derived models of UBA5-associated encephalopathy identify defects in neurodevelopment and highlight potential therapeutic avenues.

    Published in:
    Science Translational Medicine, 2025, v. 17, n. 797, p. 1, doi. 10.1126/scitranslmed.adn8417
    By:
    • Chen, Helen;
    • LaFlamme, Christy W.;
    • Wang, Yong-Dong;
    • Blan, Aidan W.;
    • Koehler, Nikki;
    • Mendonca Moraes, Renata;
    • Olszewski, Athena R.;
    • Almanza Fuerte, Edith P.;
    • Bonkowski, Emily S.;
    • Bajpai, Richa;
    • Lavado, Alfonso;
    • Pruett-Miller, Shondra M.;
    • Mefford, Heather C.
    Publication type:
    Article
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    Thick Ascending Limb Specific Inactivation of Myh9 and Myh10 Myosin Motors Results in Progressive Kidney Disease and Drives Sex-specific Cellular Adaptation in the Distal Nephron and Collecting Duct.

    Published in:
    Function, 2025, v. 6, n. 1, p. 1, doi. 10.1093/function/zqae048
    By:
    • Otterpohl, Karla L;
    • Busselman, Brook W;
    • Zimmerman, Jenna L;
    • Mukherjee, Malini;
    • Evans, Claire;
    • Graber, Kelly;
    • Thakkar, Vedant P;
    • Johnston, Jermaine G;
    • Ilyas, Arooba;
    • Gumz, Michelle L;
    • Eaton, Douglas C;
    • Sands, Jeff M;
    • Surendran, Kameswaran;
    • Chandrasekar, Indra
    Publication type:
    Article
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    Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging.

    Published in:
    GeroScience, 2024, v. 46, n. 6, p. 6009, doi. 10.1007/s11357-024-01144-w
    By:
    • Dutta, Naibedya;
    • Gerke, Joe A.;
    • Odron, Sofia F.;
    • Morris, Joseph D.;
    • Hruby, Adam;
    • Kim, Juri;
    • Torres, Toni Castro;
    • Shemtov, Sarah J.;
    • Clarke, Jacqueline G.;
    • Chang, Michelle C.;
    • Shaghasi, Hooriya;
    • Ray, Marissa N.;
    • Averbukh, Maxim;
    • Hoang, Sally;
    • Oorloff, Maria;
    • Alcala, Athena;
    • Vega, Matthew;
    • Mehta, Hemal H.;
    • Thorwald, Max A.;
    • Crews, Phillip
    Publication type:
    Article
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    High-intensity exercise training induces mitonuclear imbalance and activates the mitochondrial unfolded protein response in the skeletal muscle of aged mice.

    Published in:
    GeroScience, 2021, v. 43, n. 3, p. 1513, doi. 10.1007/s11357-020-00246-5
    By:
    • Cordeiro, André Victor;
    • Peruca, Guilherme Francisco;
    • Braga, Renata Rosseto;
    • Brícola, Rafael Santos;
    • Lenhare, Luciene;
    • Silva, Vagner Ramon Rodrigues;
    • Anaruma, Chadi Pellegrini;
    • Katashima, Carlos Kiyoshi;
    • Crisol, Barbara Moreira;
    • Barbosa, Lucas Torres;
    • Simabuco, Fernando Moreira;
    • da Silva, Adelino Sanchez Ramos;
    • Cintra, Dennys Esper;
    • de Moura, Leandro Pereira;
    • Pauli, José Rodrigo;
    • Ropelle, Eduardo Rochete
    Publication type:
    Article
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    NPC1 silent variant induces skipping of exon 11 (p.V562V) and unfolded protein response was found in a specific Niemann‐Pick type C patient.

    Published in:
    Molecular Genetics & Genomic Medicine, 2020, v. 8, n. 11, p. 1, doi. 10.1002/mgg3.1451
    By:
    • Encarnação, Marisa;
    • Coutinho, Maria Francisca;
    • Cho, Soo Min;
    • Cardoso, Maria Teresa;
    • Ribeiro, Isaura;
    • Chaves, Paulo;
    • Santos, Juliana Inês;
    • Quelhas, Dulce;
    • Lacerda, Lúcia;
    • Leão Teles, Elisa;
    • Futerman, Anthony H.;
    • Vilarinho, Laura;
    • Alves, Sandra
    Publication type:
    Article
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