Works about UBIQUITIN ligases

Results: 3404

SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102277

By:

Li Tian;
Zongzheng Zhao;
Wenying Gao;
Zirui Liu;
Xiao Li;
Wenyan Zhang;
Zhaolong Li

Publication type:

Article

Autophagy and exosome dynamics in Radiation-Induced pulmonary fibrosis: the critical role of TRIB3.

Published in:

Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03271-0

By:

Li, Na;
Zhao, Wenyue;
Li, Jiale;
Zhang, Dengfeng;
Li, Kejun;
Yang, Mengmeng;
Lu, Xinran;
Du, Liqing;
Xu, Chang;
Liu, Qiang

Publication type:

Article

Targeting the ubiquitin-proteasome pathway in systemic lupus erythematosus.

Published in:

Expert Review of Clinical Immunology, 2025, v. 21, n. 5, p. 531, doi. 10.1080/1744666X.2025.2497845

By:

Mok, Chi Chiu

Publication type:

Article

Pericytes: The forgotten controllers of a functional blood–brain barrier.

Published in:

PLoS Pathogens, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.ppat.1013145

By:

Roedel, Marshall;
Brooks, Nia;
Lamb, Tracey J.

Publication type:

Article

A bacterial RING ubiquitin ligase triggering stepwise degradation of BRISC via TOLLIP-mediated selective autophagy manipulates host inflammatory response.

Published in:

Autophagy, 2025, v. 21, n. 6, p. 1353, doi. 10.1080/15548627.2025.2468140

By:

Pan, Xinming;
Sun, Yangyang;
Liu, Jianan;
Chen, Rong;
Zhang, Zhen;
Li, Caiying;
Yao, Huochun;
Ma, Jiale

Publication type:

Article

The RAE1-STOP1 module regulates ABA sensitivity in early seedlings of Arabidopsis.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06635-2

By:

Zhang, Yuqing;
Huang, Min;
Liu, Yinyin;
Yang, Mengmeng;
Hou, Yuqi;
Huang, Chao-Feng;
Wang, Ning Ning;
Li, Lei

Publication type:

Article

Manipulation of targeted protein degradation in plant biology.

Published in:

Biochemical Society Transactions, 2025, v. 53, n. 2, p. 409, doi. 10.1042/BST20230939

By:

Rojas-Pierce, Marcela;
Bednarek, Sebastian Y.

Publication type:

Article

TRIM proteins: A 'swiss army knife' of antiviral immunity.

Published in:

PLoS Pathogens, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.ppat.1013147

By:

Chabot, Elise;
Durantel, David;
Lucifora, Julie

Publication type:

Article

Structural Dynamics, Evolutionary Significance, and Functions of Really Interesting New Gene Proteins in Ubiquitination and Plant Stress: A Review.

Published in:

DNA & Cell Biology, 2025, v. 44, n. 5, p. 214, doi. 10.1089/dna.2025.0002

By:

Agarwal, Parinita;
Chittora, Anjali;
Verma, Ayushi;
Agarwal, Pradeep K.

Publication type:

Article

STAT3-mediated upregulation of TRIM6 promotes hepatocellular carcinoma invasion through the DDX58-Snail1 axis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96548-9

By:

Wang, Yiqiao;
Wang, Jie;
Huang, Shihao;
Liu, Xingjing;
Cai, Yangbai;
Wang, Taicheng;
Zhao, Hongyan;
Lin, Xianke;
Wang, Xueguo;
Li, Peng

Publication type:

Article

Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59644-y

By:

Jiang, Bin;
Bai, Fan;
Hu, Yunfu;
Ren, Yu;
Su, Yuan;
Song, Wanxuan;
Xie, Kunxin;
Wang, Dongdong;
Pan, Junlu;
Liu, Yuying;
Feng, Yuxin;
Li, Xiaoyu;
Zhang, Hanwen;
Zhu, Xudong;
Bai, Hui;
Yang, Qing;
Ben, Jingjing;
Chen, Qi

Publication type:

Article

NOVEL PROTEOLYSIS-TARGETING CHIMERA TARGETING RAD51 FOR THE TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER.

Published in:

Journal of Physiology & Pharmacology, 2025, v. 76, n. 2, p. 197, doi. 10.26402/jpp.2025.2.09

By:

KIM, S.;
HWANG, I.;
KIM, D. S.;
CHOI, Y. J.;
JEUNG, E.-B.

Publication type:

Article

Editorial: The role of ubiquitination in disease development, progression, and prognosis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1595755

By:

Xue, Mingyang;
Jin, Wenyi

Publication type:

Article

A toolbox for ablating excitatory and inhibitory synapses.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103757

By:

Bareghamyan, Aida;
Changfeng Deng;
Daoudi, Sarah;
Yadav, Shubhash C.;
Xiaocen Lu;
Wei Zhang;
Campbell, Robert E.;
Kramer, Richard H.;
Chenoweth, David M.;
Arnold, Don B.

Publication type:

Article

Structure‐Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein‐Targeting PROTACs.

Published in:

Angewandte Chemie, 2025, v. 137, n. 19, p. 1, doi. 10.1002/ange.202501488

By:

Cui, Jibin;
Zheng, Qingyun;
Weng, Yicheng;
Zhai, Xiaoguo;
Su, Zhen;
Du, Yunxiang;
Wei, Xiaoxiong;
Yu, Yuanyuan;
Qu, Qian;
Pan, Man

Publication type:

Article

New Investigator Free Papers.

Published in:: International Journal of Rheumatic Diseases, 2025, v. 28, p. 1, doi. 10.1111/1756-185X.70263
Publication type:: Article

Clofoctol impairs the stemness of gastric cancer and induces TNF-mediated necroptosis by directly binding to RanBP2.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05723-8

By:

Liu, Yi;
Ma, Yanhui;
Zhou, Bingqian;
Bian, Bingxian;
Zhou, Yunlan;
Chen, Shiyu;
Zhang, Peng;
Shen, Lisong;
Chen, Hui

Publication type:

Article

MiR-223-3p Positively Regulates Sepsis-Induced Inflammatory Responses by Targeting the Ubiquitin Ligase FBXW7.

Published in:

Journal of Evolutionary Biochemistry & Physiology, 2025, v. 61, n. 2, p. 450, doi. 10.1134/S002209302460043X

By:

Fan, Zhaokun;
Xu, Mingxia;
Shen, Yingying

Publication type:

Article

PWWP3A disrupts the assembly of VISA/MAVS signalosome to inhibit innate immune response against RNA viruses.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59421-x

By:

Shi, Mengling;
Wang, Cong;
Chen, Zhen;
Zhou, Yidan;
Yue, Liang;
Liu, Yu;
Guo, Tiannan;
Shang, Jun;
Xu, Haotian;
Zhang, Yu;
Luo, Mengcheng;
Lei, Caoqi

Publication type:

Article

The interactome of tau phosphorylated at T217 in Alzheimer's disease human brain tissue.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02881-8

By:

Kavanagh, Tomas;
Thierry, Manon;
Balcomb, Kaleah;
Ponce, Jackeline;
Kanshin, Evgeny;
Tapia-Sealey, Alexander;
Halliday, Glenda;
Ueberheide, Beatrix;
Wisniewski, Thomas;
Drummond, Eleanor

Publication type:

Article

Protection of Armadillo/β-Catenin by Armless, a Novel Positive Regulator of Wingless Signaling.

Published in:

PLoS Biology, 2014, v. 12, n. 11, p. 1, doi. 10.1371/journal.pbio.1001988

By:

Reim, Gerlinde;
Hruzova, Martina;
Goetze, Sandra;
Basler, Konrad

Publication type:

Article

Changes in Oscillatory Dynamics in the Cell Cycle of Early <i>Xenopus laevis</i> Embryos.

Published in:

PLoS Biology, 2014, v. 12, n. 2, p. 1, doi. 10.1371/journal.pbio.1001788

By:

Tsai, Tony Y.-C.;
Theriot, Julie A.;
Ferrell Jr, James E.

Publication type:

Article

A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001657

By:

Wong, Jack Jing Lin;
Li, Song;
Lim, Edwin Kok Hao;
Wang, Yan;
Wang, Cheng;
Zhang, Heng;
Kirilly, Daniel;
Wu, Chunlai;
Liou, Yih-Cherng;
Wang, Hongyan;
Yu, Fengwei

Publication type:

Article

A Meiosis-Specific Form of the APC/C Promotes the Oocyte-to-Embryo Transition by Decreasing Levels of the Polo Kinase Inhibitor Matrimony.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001648

By:

Whitfield, Zachary J.;
Chisholm, Jennifer;
Hawley, R. Scott;
Orr-Weaver, Terry L.

Publication type:

Article

Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome.

Published in:

PLoS Biology, 2013, v. 11, n. 2, p. 1, doi. 10.1371/journal.pbio.1001478

By:

Cao, Cong;
Rioult-Pedotti, Mengia S.;
Migani, Paolo;
Yu, Crystal J.;
Tiwar, Rakesh;
Parang, Keykavous;
Spaller, Mark R.;
Goebel, Dennis J.;
Marshall, John

Publication type:

Article

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

Published in:

PLoS Biology, 2012, v. 10, n. 12, p. 1, doi. 10.1371/journal.pbio.1001440

By:

Xiong, Xin;
Hao, Yan;
Sun, Kan;
Li, Jiaxing;
Li, Xia;
Mishra, Bibhudatta;
Soppina, Pushpanjali;
Wu, Chunlai;
Hume, Richard I.;
Collins, Catherine A.

Publication type:

Article

CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock.

Published in:

PLoS Biology, 2012, v. 10, n. 8, p. 1, doi. 10.1371/journal.pbio.1001367

By:

Grima, Brigitte;
Dognon, Alexandre;
Lamouroux, Annie;
Chélot, Elisabeth;
Rouyer, François

Publication type:

Article

Haplotype structure in grain weight gene GW2 and its association with grain characteristics in rice.

Published in:

Euphytica, 2013, v. 192, n. 1, p. 55, doi. 10.1007/s10681-012-0852-4

By:

Dixit, N.;
Dokku, P.;
Amitha Mithra, S.;
Parida, S.;
Singh, A.;
Singh, N.;
Mohapatra, T.

Publication type:

Article

In vitro ubiquitination of Mycobacterium tuberculosis by E3 ubiquitin ligase, MKRN1.

Published in:

Biotechnology Letters, 2020, v. 42, n. 8, p. 1527, doi. 10.1007/s10529-020-02873-6

By:

Subrahmanian, Meenu;
Marimuthu, Jeya;
Sairam, Thiagarajan;
Sankaran, Ramalingam

Publication type:

Article

UHRF2 promotes DNA damage response by decreasing p21 via RING finger domain.

Published in:

Biotechnology Letters, 2018, v. 40, n. 8, p. 1181, doi. 10.1007/s10529-018-2577-5

By:

Wang, Yangyang;
Yan, Xinke;
Zeng, Shengyuan;
Zhang, Ting;
Cheng, Fengjuan;
Chen, Rongjuan;
Duan, Changzhu

Publication type:

Article

Transcriptome and photosynthetic analyses provide new insight into the molecular mechanisms underlying heat stress tolerance in Rhododendron × pulchrum Sweet.

Published in:

Tree Physiology, 2024, v. 44, n. 1, p. 1, doi. 10.1093/treephys/tpad133

By:

Cheng, Hefeng;
Wan, Ziyun;
Xu, Yanxia;
Shen, Jianshuang;
Li, Xueqin;
Jin, Songheng

Publication type:

Article

Inhibition of the Arg/N-end rule pathway-mediated proteolysis by dipeptide-mimetic molecules.

Published in:

Amino Acids, 2016, v. 48, n. 1, p. 235, doi. 10.1007/s00726-015-2083-1

By:

Kitamura, Kenji

Publication type:

Article

OsHRZ1 negatively regulates rice resistant to Magnaporthe oryzae infection by targeting OsVOZ2.

Published in:

Transgenic Research, 2024, v. 33, n. 5, p. 489, doi. 10.1007/s11248-024-00415-8

By:

Sun, Jia-ying;
Zhou, Zeng-ran;
Wang, Yu-qi;
Zhu, Dong-yu;
Ma, Dian-rong

Publication type:

Article

Mathematical Simulation of p53-Mdm2 Protein Biological System Regulation.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 157, n. 4, p. 535, doi. 10.1007/s10517-014-2608-8

By:

Voropaeva, O.;
Shokin, Yu.;
Nepomnyashchikh, L.;
Senchukova, S.

Publication type:

Article

Mathematical Modeling of Functioning of the p53-Mdm2 Protein System.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 157, n. 2, p. 291, doi. 10.1007/s10517-014-2548-3

By:

Voropaeva, O.;
Shokin, Yu.;
Nepomnyashchikh, L.;
Senchukova, S.

Publication type:

Article

LncRNA Fendrr inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by downregulating p53 expression.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 11, p. 1211, doi. 10.1111/jphp.13298

By:

Xiang Li;
Liangchun Ni;
Weixin Wang;
Liang Zong;
Bi Yao

Publication type:

Article

LncRNA Fendrr inhibits hypoxia/reoxygenation‐induced cardiomyocyte apoptosis by downregulating p53 expression.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 9, p. 1211, doi. 10.1111/jphp.13298

By:

Li, Xiang;
Ni, Liangchun;
Wang, Weixin;
Zong, Liang;
Yao, Bi

Publication type:

Article

MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail.

Published in:

BMC Molecular & Cell Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12860-021-00385-3

By:

Sanford, Jack D.;
Yang, Jing;
Han, Jing;
Tollini, Laura A.;
Jin, Aiwen;
Zhang, Yanping

Publication type:

Article

SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00486-6

By:

Lai, Xianning;
Lui, Sarah Kit Leng;
Lam, Hiu Yan;
Adachi, Yuta;
Sim, Wen Jing;
Vasilevski, Natali;
Armstrong, Nicola J.;
Bridgeman, Stephanie Claire;
Main, Nathan Michael;
Tan, Tuan Zea;
Tirnitz-Parker, Janina E. E.;
Thiery, Jean Paul;
Ebi, Hiromichi;
Kumar, Alan Prem;
Eichhorn, Pieter Johan Adam

Publication type:

Article

Pioneering protein degradation for agricultural applications.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08013-y

By:

Morgan, Gina L.;
Dickson, Hamilton;
Ford, Breanna;
Noras, Aleksandra;
Bremmer, Steven C.;
Watts, Brian E.;
Pilotte, Joseph;
Anderson, Ed;
Sullivan, Eric D.;
Stoner, Mikayla;
Ouedraogo, Daniel;
Saltzberg, Daniel J.;
Pothula, Karunakar R.;
Ingram, Paul;
Catalano, John;
Lillich, Melina;
Kolbe, Carl-Christian;
Pfeiffer, Anne;
Ladner, Christopher C.;
Gattis, Sam

Publication type:

Article

LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02072-6

By:

Liu, Zhan;
Fan, Kexin;
Abudukeremu, Aikedaimu;
Gao, Min;
Tan, Xinyue;
Mao, Xiaojuan;
Li, Xinyu;
Ma, Wenting;
Ma, Xusheng;
Li, Caolong;
Yang, Yinglai;
Tu, Kangsheng;
Chen, Jing;
Zhang, Yilei;
Guan, Yaqun

Publication type:

Article

NAP1L1 regulates BIRC2 ubiquitination modification via E3 ubiquitin ligase UBR4 and hence determines hepatocellular carcinoma progression.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01927-2

By:

Zhang, Shi-Long;
Zhang, Shen-Jie;
Li, Lian;
Zhang, Ye-Wei;
Wang, Zhi;
Wang, Long;
Lu, Jie-Yu;
Chen, Teng-Xiang;
Zuo, Shi

Publication type:

Article

FBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01919-2

By:

Shen, Zhigang;
Dong, Tao;
Yong, Hongmei;
Deng, Chuyin;
Chen, Changxiu;
Chen, Xintian;
Chen, Miaolei;
Chu, Sufang;
Zheng, Junnian;
Li, Zhongwei;
Bai, Jin

Publication type:

Article

BZW2 promotes malignant progression in lung adenocarcinoma through enhancing the ubiquitination and degradation of GSK3β.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01879-7

By:

Jin, Kai;
Li, Yongmeng;
Wei, Ruyuan;
Liu, Yanfei;
Wang, Shuai;
Tian, Hui

Publication type:

Article

The E3 ubiquitin ligase TRIM39 modulates renal fibrosis induced by unilateral ureteral obstruction through regulating proteasomal degradation of PRDX3.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-023-01785-4

By:

Jian, Jun;
Liu, Yunxun;
Zheng, Qingyuan;
Wang, Jingsong;
Jiang, Zhengyu;
Liu, Xiuheng;
Chen, Zhiyuan;
Wan, Shanshan;
Liu, Hao;
Wang, Lei

Publication type:

Article

The involvement of E3 ubiquitin ligases in the development and progression of colorectal cancer.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01760-z

By:

Chen, Jie;
Feng, Haimei;
Wang, Yiting;
Bai, Xiaoming;
Sheng, Siqi;
Li, Huiyu;
Huang, Mengxi;
Chu, Xiaoyuan;
Lei, Zengjie

Publication type:

Article

Dynamic RBM47 ISGylation confers broad immunoprotection against lung injury and tumorigenesis via TSC22D3 downregulation.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01736-z

By:

Ding, Shihui;
Pang, Xiquan;
Luo, Shaoxiang;
Gao, Huili;
Li, Bo;
Yue, Junqiu;
Chen, Jian;
Hu, Sheng;
Tu, Zepeng;
He, Dong;
Kuang, Youyi;
Dong, Zhiqiang;
Zhang, Min

Publication type:

Article

TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01731-4

By:

Ma, Qinmei;
Yu, Jialin;
Liu, Li;
Ma, Xiaoyan;
Zhang, Jiaxue;
Zhang, Jiamei;
Wang, Xiaoping;
Deng, Guangcun;
Wu, Xiaoling

Publication type:

Article

USP32 deubiquitinase: cellular functions, regulatory mechanisms, and potential as a cancer therapy target.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01629-1

By:

Li, Shuang;
Song, Yang;
Wang, Kexin;
Liu, Guoxiang;
Dong, Xiaolei;
Yang, Fanghao;
Chen, Guang;
Cao, Can;
Zhang, Huhu;
Wang, Mengjun;
Li, Ya;
Zeng, Teng;
Liu, Chunyan;
Li, Bing

Publication type:

Article

miR-221/222 induce instability of p53 By downregulating deubiquitinase YOD1 in acute myeloid leukemia.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01537-4

By:

Pei, Han Zhong;
Peng, Zhiyong;
Zhuang, Xiaomei;
Wang, Xiaobo;
Lu, Bo;
Guo, Yao;
Zhao, Yuming;
Zhang, Dengyang;
Xiao, Yunjun;
Gao, Tianshun;
Yu, Liuting;
He, Chunxiao;
Wu, Shunjie;
Baek, Suk-Hwan;
Zhao, Zhizhuang Joe;
Xu, Xiaojun;
Chen, Yun

Publication type:

Article