Works matching DE "UBIQUITIN"

Results: 5000

Targeted protein degradation by KLHDC2 ligands identified by high-throughput screening.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.106844

By:

Han Zhou;
Tonglian Zhou;
Wenli Yu;
Liping Liu;
Yeonjin Ko;
Johnson, Kristen A.;
Wilson, Ian A.;
Schultz, Peter G.;
Bollong, Michael J.

Publication type:

Article

Mechanism of nascent chain removal by the ribosome-associated quality control complex.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61235-w

By:

Li, Wenyan;
Scheel, Talia;
Shen, Peter S.

Publication type:

Article

Structural insights into the human HRD1 ubiquitin ligase complex.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61143-z

By:

Guo, Liling;
Liu, Guoyun;
He, Jingjing;
Jia, Xiaoxiao;
He, Yonglin;
Wang, Zhenhua;
Qian, Hongwu

Publication type:

Article

Decoding polyubiquitin regulation of K<sub>V</sub>7. 1 (KCNQ1) surface expression with engineered linkage-selective deubiquitinases.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60893-0

By:

Shanmugam, Sri Karthika;
Kanner, Scott A.;
Zou, Xinle;
Amarh, Enoch;
Choudhury, Papiya;
Soni, Rajesh;
Kass, Robert S.;
Colecraft, Henry M.

Publication type:

Article

An adaptive peptide-binding site in ubiquitin receptor hRpn13 revealed by structural studies.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60843-w

By:

Hassan, Bakar;
Chandravanshi, Monika;
Ng, Martin Y.;
Negi, Hitendra;
Wilson, Brice A. P.;
Walters, Kylie J.

Publication type:

Article

E3 ubiquitin ligase Smurf1 promotes cardiomyocyte pyroptosis by mediating ubiquitin-dependent degradation of TRIB2 in a rat model of heart failure.

Published in:

International Reviews of Immunology, 2025, v. 44, n. 4, p. 165, doi. 10.1080/08830185.2024.2434058

By:

Liu, Wei;
Cai, Xin;
Duan, Shiying;
Shen, Jihua;
Wu, Jiayuan;
Zhou, Zhengwei;
Yu, Kaili;
He, Caihong;
Wang, Yuqin

Publication type:

Article

The Plasmodium falciparum RING Finger Protein Pf RNF1 Forms an Interaction Network with Regulators of Sexual Development.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5470, doi. 10.3390/ijms26125470

By:

Farrukh, Afia;
Musa, Sherihan;
Distler, Ute;
Tenzer, Stefan;
Pradel, Gabriele;
Ngwa, Che Julius

Publication type:

Article

Interplay between viruses and host sumoylation pathways.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 6, p. 400, doi. 10.1038/nrmicro3015

By:

Everett, Roger D.;
Boutell, Chris;
Hale, Benjamin G.

Publication type:

Article

Antiviral immunity: TRIM5 moonlights as a pattern recognition receptor.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 6, p. 398, doi. 10.1038/nrmicro2582

By:

Jermy, Andrew

Publication type:

Article

Bacterial pathogenesis: Legionella effector under friendly fire.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 2, p. 80, doi. 10.1038/nrmicro2509

By:

Jermy, Andrew

Publication type:

Article

Bacterial pathogenesis: Targeting SUMO.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 6, p. 386, doi. 10.1038/nrmicro2371

By:

David, Rachel

Publication type:

Article

Archaea: Singled out from the crowd.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 3, p. 160, doi. 10.1038/nrmicro2316

By:

van Ooij, Christiaan

Publication type:

Article

Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001721

By:

Huang, Shoujun;
Zhang, Zhao;
Zhang, Chunxia;
Lv, Xiangdong;
Zheng, Xiudeng;
Chen, Zhenping;
Sun, Liwei;
Wang, Hailong;
Zhu, Yuanxiang;
Zhang, Jing;
Yang, Shuyan;
Lu, Yi;
Sun, Qinmiao;
Tao, Yi;
Liu, Feng;
Zhao, Yun;
Chen, Dahua

Publication type:

Article

p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells.

Published in:

PLoS Biology, 2012, v. 10, n. 2, p. 1, doi. 10.1371/journal.pbio.1001268

By:

Jain, Abhinav K.;
Allton, Kendra;
Iacovino, Michelina;
Mahen, Elisabeth;
Milczarek, Robert J.;
Zwaka, Thomas P.;
Kyba, Michael;
Barton, Michelle Craig

Publication type:

Article

An OBSL1-Cul7Fbxw8 Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning.

Published in:: PLoS Biology, 2011, v. 9, n. 5, p. 1, doi. 10.1371/journal.pbio.1001060
Publication type:: Article

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway.

Published in:

PLoS Biology, 2011, v. 9, n. 3, p. 1, doi. 10.1371/journal.pbio.1000605

By:

Ernst, Robert;
Claessen, Jasper H. L.;
Mueller, Britta;
Sanyal, Sumana;
Spooner, Eric;
van der Veen, Annemarthe G.;
Kirak, Oktay;
Schlieker, Christian D.;
Weihofen, Wilhelm A.;
Ploegh, Hidde L.

Publication type:

Article

Protein's "Part-Time Job" Reveals New Facet of Signaling Pathway.

Published in:

PLoS Biology, 2010, v. 8, n. 11, p. 1, doi. 10.1371/journal.pbio.1001001

By:

Inman, Mason

Publication type:

Article

Non-Canonical NF-κB Activation and Abnormal B Cell Accumulation in Mice Expressing Ubiquitin Protein Ligase-Inactive c-IAP2.

Published in:

PLoS Biology, 2010, v. 8, n. 10, p. 1, doi. 10.1371/journal.pbio.1000518

By:

Conze, Dietrich B.;
Yongge Zhao;
Ashwell, Jonathan D.

Publication type:

Article

SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks.

Published in:

PLoS Biology, 2009, v. 7, n. 12, p. 1, doi. 10.1371/journal.pbio.1000252

By:

Ouyang, Karen J.;
Woo, Leslie L.;
Jianmei Zhu;
Dezheng Huo;
Matunis, Michael J.;
Ellis, Nathan A.

Publication type:

Article

SUMO-Specific Protease 2 Is Essential for Modulating p53-Mdm2 in Development of Trophoblast Stem Cell Niches and Lineages.

Published in:

PLoS Biology, 2008, v. 6, n. 12, p. e310, doi. 10.1371/journal.pbio.0060310

By:

Shang-Yi Chiu;
Naoya Asai;
Costantini, Frank;
Wei Hsu

Publication type:

Article

Correction: A Ubiquitin Ligase Complex Regulates Caspase Activation During Sperm Differentiation in Drosophila.

Published in:

2007

By:

Arama, Eli;
Bader, Maya;
Rieckhof, Gabrielle E.;
Stellar, Hermann

Publication type:

Correction Notice

A Ubiquitin Ligase Complex Regulates Caspase Activation During Sperm Differentiation in Drosophila.

Published in:

PLoS Biology, 2007, v. 5, n. 10, p. e251, doi. 10.1371/journal.pbio.0050251

By:

Arama, Eli;
Bader, Maya;
Rieckhof, Gabrielle E.;
Steller, Hermann

Publication type:

Article

A Role for PCNA Ubiquitination in Immunoglobulin Hypermutation.

Published in:

PLoS Biology, 2006, v. 4, n. 11, p. 1947, doi. 10.1371/journal.pbio.0040366

By:

Arakawa, Hiroshi;
Moldovan, George-Lucian;
Saribasak, Huseyin;
Saribasak, Nesibe Nur;
Jentsch, Stefan;
Buerstedde, Jean-Mari

Publication type:

Article

Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes.

Published in:

PLoS Biology, 2006, v. 4, n. 8, p. e267, doi. 10.1371/journal.pbio.0040267

By:

Sharon, Michal;
Taverner, Thomas;
Ambroggio, Xavier I.;
Deshaies, Raymond J.;
Robinson, Carol V.

Publication type:

Article

Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e27, doi. 10.1371/journal.pbio.0040027

By:

Hu, Min;
Gu, Lichuan;
Li, Muyang;
Jeffrey, Philip D.;
Gu, Wei;
Shi, Yigong

Publication type:

Article

Two Distinct E3 Ubiquitin Ligases Have Complementary Functions in the Regulation of Delta and Serrate Signaling in Drosophila.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 688, doi. 10.1371/journal.pbio.0030096

By:

Borgne, Roland Le;
Remaud, Sylvie;
Hamel, Sophie;
Schweisguth, François

Publication type:

Article

Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans.

Published in:

PLoS Biology, 2004, v. 2, n. 10, p. 1549, doi. 10.1371/journal.pbio.0020289

By:

Bishop, Tammie;
Laul, Kah Weng;
Epstein, Andrew C. R.;
Kim, Stuart K.;
Jiang, Min;
O'Rourke, Delia;
Pugh, Christopher W.;
Gleadle, Jonathan M.;
Taylor, Martin S.;
Hodgkin, Jonathan;
Ratcliffe, Peter J.

Publication type:

Article

The Proteasome and the Delicate Balance between Destruction and Rescue.

Published in:

PLoS Biology, 2004, v. 2, n. 1, p. 0025, doi. 10.1371/journal.pbio.0020013

By:

Glickman, Michael H.;
Adir, Noam

Publication type:

Article

Inhibition of HIF2 a Is Sufficient to Suppress pVHL-Defective Tumor Growth.

Published in:

PLoS Biology, 2003, v. 1, n. 3, p. 339, doi. 10.1371/journal.pbio.0000083

By:

Kondo, Keiichi;
Kim, William Y.;
Lechpammer, Mirna;
Kaelin Jr., William G.

Publication type:

Article

Association of donor small ubiquitin‐like modifier 4 rs237025 genetic variant with tacrolimus elimination in the early period after liver transplantation.

Published in:

Liver International, 2018, v. 38, n. 4, p. 724, doi. 10.1111/liv.13597

By:

Zhang, Tao;
Liu, Yuan;
Fan, Junwei;
Peng, Zhihai;
Zeng, Rong;
Ling, Qi;
Wen, Peihao

Publication type:

Article

Hepatocellular carcinomas with intracellular hyaline bodies have a poor prognosis.

Published in:

Liver International, 2017, v. 37, n. 4, p. 600, doi. 10.1111/liv.13325

By:

Aigelsreiter, Ariane;
Neumann, Jens;
Pichler, Martin;
Halasz, Judith;
Zatloukal, Kurt;
Berghold, Andrea;
Douschan, Philipp;
Rainer, Florian;
Stauber, Rudolf;
Haybaeck, Johannes;
Denk, Helmut;
Lackner, Carolin

Publication type:

Article

Gene expression in HCV-associated hepatocellular carcinoma – upregulation of a gene encoding a protein related to the ubiquitin-conjugating enzyme.

Published in:

Liver International, 2003, v. 23, n. 5, p. 329, doi. 10.1034/j.1478-3231.2003.00862.x

By:

El-Nady, Ghada M.;
Ling, Roger;
Harrison, Tim J.

Publication type:

Article

Role of electrostatics in the thermal stability of ubiquitin.

Published in:

Journal of Thermal Analysis & Calorimetry, 2006, v. 86, n. 2, p. 311, doi. 10.1007/s10973-005-7467-0

By:

Sciacca, M. F. M.;
Milardi, D.;
Pappalardo, M.;
La Rosa, C.;
Grasso, D. M.

Publication type:

Article

CUL4A is overexpressed in human pituitary adenomas and regulates pituitary tumor cell proliferation.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 3, p. 625, doi. 10.1007/s11060-013-1349-2

By:

Xu, Yangyang;
Wang, Yunshan;
Ma, Guangxin;
Wang, Qin;
Wei, Guangwei

Publication type:

Article

Ubiquitin, the centrosome, and chromosome segregation.

Published in:

Chromosome Research, 2016, v. 24, n. 1, p. 77, doi. 10.1007/s10577-015-9511-7

By:

Zhang, Ying;
Galardy, Paul

Publication type:

Article

In human pachytene spermatocytes, SUMO protein is restricted to the constitutive heterochromatin.

Published in:

Chromosome Research, 2008, v. 16, n. 5, p. 761

By:

Danielle Depetris;
Judith Luciani;
Cecile Mignon-Ravix;
Michael Mitchell;
Marie-Genevieve Mattei

Publication type:

Article

Atomic Tailoring of Ubiquitin Side Chains Influences E2‐Mediated Ubiquitin Chain Formation.

Published in:

Helvetica Chimica Acta, 2024, v. 107, n. 7, p. 1, doi. 10.1002/hlca.202400003

By:

Song, Haewon;
Mikami, Toshiki;
Majima, Sohei;
Bode, Jeffrey W.

Publication type:

Article

Role of RNA in the regulation of gene expression.

Published in:

Nutrition Reviews, 2008, v. 66, p. S31, doi. 10.1111/j.1753-4887.2008.00063.x

By:

Morris, Kevin V.

Publication type:

Article

Proteostasis in ice: the role of heat shock proteins and ubiquitin in the freeze tolerance of the intertidal mussel, Mytilus trossulus.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2023, v. 193, n. 2, p. 155, doi. 10.1007/s00360-022-01473-2

By:

Gill, Lauren T.;
Kennedy, Jessica R.;
Marshall, Katie E.

Publication type:

Article

Is cold the new hot? Elevated ubiquitin-conjugated protein levels in tissues of Antarctic fish as evidence for cold-denaturation of proteins in vivo.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2007, v. 177, n. 8, p. 857, doi. 10.1007/s00360-007-0183-2

By:

Todgham, Anne E.;
Hoaglund, Elizabeth A.;
Hofmann, Gretchen E.

Publication type:

Article

Ubiquitin conjugate dynamics in the gut and liver of hibernating ground squirrels.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2002, v. 172, n. 3, p. 269, doi. 10.1007/s00360-002-0252-5

By:

vanBreukelen, F.;
Carey, H. V.

Publication type:

Article

Characterization of ATP-dependent proteolysis in embryos of the brine shrimp, Artemia franciscana.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2000, v. 170, n. 2, p. 125, doi. 10.1007/s003600050267

By:

van Breukelen, F.;
Hand, S. C.

Publication type:

Article

Evaluation of the agonal stress: can immunohistochemical detection of ubiquitin in the locus coeruleus be useful?

Published in:

International Journal of Legal Medicine, 2011, v. 125, n. 3, p. 333, doi. 10.1007/s00414-010-0434-8

By:

Piette, Michel H. A.;
Pieters, Stéphanie E. P.;
De Letter, Els A.

Publication type:

Article

A positive genetic selection for transmembrane domain mutations in HRD1 underscores the importance of Hrd1 complex integrity during ERAD.

Published in:

Current Genetics, 2022, v. 68, n. 2, p. 227, doi. 10.1007/s00294-022-01227-1

By:

Nakatsukasa, Kunio;
Wigge, Sylvia;
Takano, Yuki;
Kawarasaki, Tomoyuki;
Kamura, Takumi;
Brodsky, Jeffrey L.

Publication type:

Article

Cdc48/Shp1 participates in dissociation of protein complexes to regulate their activity.

Published in:

Current Genetics, 2021, v. 67, n. 2, p. 263, doi. 10.1007/s00294-020-01136-1

By:

Lauinger, Linda;
Flick, Karin;
Kaiser, Peter

Publication type:

Article

Multiple chemo-genetic interactions between a toxic metabolite and the ubiquitin pathway in yeast.

Published in:

Current Genetics, 2018, v. 64, n. 6, p. 1275, doi. 10.1007/s00294-018-0843-7

By:

Albrecht, Delphine;
Hürlimann, Hans C.;
Ceschin, Johanna;
Saint-Marc, Christelle;
Pinson, Benoît;
Daignan-Fornier, Bertrand

Publication type:

Article

Ubiquitin-like activating enzymes BcAtg3 and BcAtg7 participate in development and pathogenesis of Botrytis cinerea.

Published in:

Current Genetics, 2018, v. 64, n. 4, p. 919, doi. 10.1007/s00294-018-0810-3

By:

Ren, Weichao;
Sang, Chengwei;
Shi, Dongya;
Song, Xiushi;
Zhou, Mingguo;
Chen, Changjun

Publication type:

Article

Intron specificity in pre-mRNA splicing.

Published in:

Current Genetics, 2018, v. 64, n. 4, p. 777, doi. 10.1007/s00294-017-0802-8

By:

Mishra, Shravan Kumar;
Thakran, Poonam

Publication type:

Article

Regulation of TORC1 by ubiquitin through non-covalent binding.

Published in:

Current Genetics, 2016, v. 62, n. 3, p. 553, doi. 10.1007/s00294-016-0581-7

By:

Jiang, Yu

Publication type:

Article

Exploiting the ubiquitin and phosphoinositide pathways by the Legionella pneumophila effector, SidC.

Published in:

Current Genetics, 2016, v. 62, n. 1, p. 105, doi. 10.1007/s00294-015-0521-y

By:

Wasilko, David;
Mao, Yuxin

Publication type:

Article