Works about TYPE I interferons

Results: 3248

The cGAS-STING signaling pathway in the regulation of pulmonary infections: a systematic review.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1628481

By:

Xu, Qinchao;
Zhu, Jiayu

Publication type:

Article

STAT1-mediated interferon signaling in the hematopoietic system is essential for restricting Usutu virus infection in vivo.

Published in:

PLoS Neglected Tropical Diseases, 2025, v. 19, n. 7, p. 1, doi. 10.1371/journal.pntd.0013317

By:

Nelson, Amy N.;
Sinha, Saloni;
Mullin, Sydney J.;
Carver, Sebastian S.;
Cafiero, Thomas R.;
Lin, Aaron E.;
Schwartz, Robert E.;
Ploss, Alexander

Publication type:

Article

The alpha-coronavirus E protein inhibits the JAK-STAT pathway signaling by triggering STAT2 degradation through OPTN- and NBR1-mediated selective autophagy.

Published in:

Autophagy, 2025, v. 21, n. 8, p. 1644, doi. 10.1080/15548627.2025.2479671

By:

Huang, Zhao;
Gao, Chenyang;
Huang, Shaohong;
Lin, Sizhan;
Zhang, WenBo;
You, Jianyi;
Chen, Xiongnan;
Zhou, Pei;
Zhang, Guihong;
Gong, Lang

Publication type:

Article

TAX1BP1-dependent autophagic degradation of STING1 impairs anti-tumor immunity.

Published in:

Autophagy, 2025, v. 21, n. 8, p. 1802, doi. 10.1080/15548627.2025.2471736

By:

Zhang, Ruoxi;
Yu, Chunhua;
Zeh, Herbert J.;
Kroemer, Guido;
Klionsky, Daniel J.;
Tang, Daolin;
Kang, Rui

Publication type:

Article

Increased ROS levels activate AMPK-ULK1-mediated mitophagy to promote pseudorabies virus replication.

Published in:

Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01595-9

By:

Zhao, Yuan;
Qi, Xiaoyi;
Zhu, Zhenbang;
Wang, Wenqiang;
Wen, Wei;
Li, Xiangdong

Publication type:

Article

Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01818-3

By:

Kong, Lingwenyao;
Li, Juanjuan;
Gao, Lu;
Zhao, Yonggang;
Chen, Weixian;
Wang, Xumeng;
Wang, Songlin;
Wang, Fu

Publication type:

Article

Histopathological Patterns and Immunohistochemical Markers in Early Detection of Cutaneous Lupus Erythematosus.

Published in:

European Journal of Cardiovascular Medicine, 2025, v. 15, n. 6, p. 576

By:

Khandelwal, Purusharth Bhavarlal;
Patel, Mayankkumar Vishnubhai;
Rathod, Jignesh Dhirubhai

Publication type:

Article

HIGHLIGHTED ARTICLES.

Published in:: Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 2, p. 288, doi. 10.1002/cpt.3742
Publication type:: Article

The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor.

Published in:

PLoS Pathogens, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.ppat.1013319

By:

Ren, Haojie;
Wang, Yanjin;
Li, Lian-Feng;
Shi, Lan-Fang;
Ma, Yu-He;
Fan, Jun-Hao;
Pan, Xiao-Ya;
Shao, Han-Cheng;
Zhang, Yuhang;
Han, Shichong;
Wan, Bo;
Qiu, Hua-Ji;
Zhang, Gai-Ping;
Li, Su;
He, Wen-Rui

Publication type:

Article

Stimulator of Interferon Genes (STING)-Type I Interferon Signaling: Bridging Immunity and Pain.

Published in:

Journal of Integrative Neuroscience, 2025, v. 24, n. 6, p. 1, doi. 10.31083/JIN33414

By:

Ti-Chuan Chiu;
Yu-Yu Li;
Chia-Hung Yu;
Kuo-Chuan Hung;
Chin-Chen Chu;
Ping-Hsun Feng;
Ping-Heng Tan

Publication type:

Article

Dysregulated type I/III interferon system in circulation from patients with anti-MDA5-positive dermatomyositis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10895-1

By:

Yoshida, Akira;
Gono, Takahisa;
Okazaki, Yuka;
Shimizu, Masumi;
Igarashi, Yutaka;
Kitahara, Yoshihiro;
Fujisawa, Tomoyuki;
Suda, Takafumi;
Yokobori, Shoji;
Morita, Rimpei;
Kuwana, Masataka

Publication type:

Article

An Integrative Mechanistic Model of Type 1 IFN‐Mediated Inflammation in Systemic Lupus Erythematosus.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 7, p. 1225, doi. 10.1002/psp4.70043

By:

Volkova, Alina;
Sokolov, Victor;
Tettamanti, Florencia;
Verma, Meghna;
Ugolkov, Yaroslav;
Peskov, Kirill;
Tang, Weifeng;
Kimko, Holly

Publication type:

Article

Poxvirus Vectors Activate Human NK and MAIT Cells in a Type I Interferon, IL‐18, and Monocyte‐Dependent Manner.

Published in:

Journal of Immunology Research, 2025, v. 2025, p. 1, doi. 10.1155/jimr/1203141

By:

N'guessan, Kombo F.;
Shubin, Zhanna;
Machmach, Kawthar;
Sandberg, Johan K.;
Ake, Julie A.;
Vasan, Sandhya;
Eller, Michael A.;
Paquin-Proulx, Dominic;
Gurumallesh, Poorani

Publication type:

Article

Type I Interferons in SARS-CoV-2 Cutaneous Infection: Is There a Role in Antiviral Defense?

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6049, doi. 10.3390/ijms26136049

By:

Yendo, Tatiana Mina;
Orfali, Raquel Leão;
Pereira, Naiura Vieira;
Pereira, Natalli Zanete;
Ramos, Yasmim Álefe Leuzzi;
Kawakami, Joyce Tiyeko;
Duarte-Neto, Amaro Nunes;
Sotto, Mirian Nacagami;
Silva, Luiz Fernando Ferraz;
Duarte, Alberto José da Silva;
Sato, Maria Notomi;
Aoki, Valeria

Publication type:

Article

Insulin Modulates NK Cell Activity in Liver Fibrosis MASH Patients via the STING Pathway.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 941, doi. 10.3390/cells14130941

By:

Amer, Johnny;
Salhab, Ahmad;
Ariel, Amiram;
Safadi, Rifaat

Publication type:

Article

The cGAS-STING pathway: a dual regulator of immune response in cancer and therapeutic implications.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06843-2

By:

Huang, Zhanghao;
Zhu, Jun;
Zhou, You Lang;
Shi, Jiahai

Publication type:

Article

Ropeginterferon alfa-2b as a promising alternative to conventional interferon in CDA type 1: a case report of two siblings.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01785-x

By:

Yang, Tyng-Wei;
Tsai, Xavier Cheng-Hong;
Fu, Yu-Hsuan;
Lin, Liang-In;
Hou, Hsin-An

Publication type:

Article

Genome-wide identification of the interferon complex establishes IFNf in Cypriniformes.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02319-3

By:

Huang, Yu;
Zhang, Lei;
Yang, Xinyi;
Li, Yuqing;
Li, Zeyu;
Zhang, Qianqian;
Xu, Zhen

Publication type:

Article

RNF213 regulates blood‒brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection.

Published in:

PLoS Pathogens, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.ppat.1013333

By:

Li, Yanfeng;
Xie, Qingqing;
Yang, Luyu;
Jiang, Qian;
Liu, Zhiping;
Gao, Chengjiang;
Qi, Xiaopeng;
Xu, Tao

Publication type:

Article

African swine fever virus MGF505-4R facilitates cGAS degradation through TOLLIP-mediated selective autophagy and inhibits the formation of ISGF3 to evade innate immunity.

Published in:

Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01569-x

By:

Yao, Manman;
Li, Pengfei;
Li, Xiangmin;
Li, Wentao;
Qian, Ping

Publication type:

Article

Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced antiviral capacity.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61254-7

By:

Gonzalez, Victoria;
Lobb, Briallen;
Côté, Jacob;
Bhuinya, Arkadeb;
Tubb, Adriana G.;
Nuthalapati, Stephen S.;
Asavajaru, Akarin;
Zhou, Yan;
Misra, Vikram;
Falzarano, Darryl;
Sweeney, Trevor R.;
Gobeil, Sophie M. C.;
Wang, Linfa;
Doxey, Andrew C.;
Banerjee, Arinjay

Publication type:

Article

Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60941-9

By:

Gregorova, Michaela;
Santopaolo, Marianna;
Garner, Lucy C.;
Hayati, Rahma F.;
Diamond, Divya;
Ramamurthy, Narayan;
Tran, Vi Thuy;
Nguyen, Nguyet Minh;
Heesom, Kate J.;
Nguyen, Vuong Lam;
Jones, Eben;
Nsubuga, Mike;
Luscombe, Curtis;
Vo, Hoa Thi My;
Ho, Chanh Quang;
Nguyen, Chau Thi Xuan;
Dong, Tam Thi Hoai;
Huynh, Duyen Thi Le;
Cao, Tam Thi;
Davidson, Andrew D.

Publication type:

Article

Orchestrating intratumoral DC-T cell immunity for enhanced tumor control via radiotherapy-activated TLR7/8 prodrugs in mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60769-3

By:

Yin, Xiaozhe;
Ding, Zexuan;
Yu, Li;
Zhang, Xuhao;
Gao, Yu;
Li, Yiyan;
Liu, Zhibo;
Fu, Yang-Xin

Publication type:

Article

Type 1 interferon signature and allograft inflammatory factor-1 contribute to refractoriness to TNF inhibition in ankylosing spondylitis.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60445-6

By:

Song, Woogil;
Lee, Eunyoung Emily;
Park, Seongwan;
Choi, Baekgyu;
Kim, Min-Gang;
Ban, Seo Yoon;
Choi, Se Rim;
Kim, Jeong Yeon;
Kim, Seon Uk;
Kim, Jong-Il;
Shin, Eui-Cheol;
Jung, Inkyung;
Lee, Jeong Seok;
Lee, Eun Young

Publication type:

Article

A Sjögren-szindróma patogenezise és terápiája.

Published in:

Immunology Quarterly / Immunológiai Szemle, 2025, v. 17, n. 2, p. 7

By:

VIRÁG, BOHÁCSI;
LÁSZLÓ, KOVÁCS

Publication type:

Article

Peran Anifrolumab dan Belimab pada Sle.

Published in:

Cerdika : Jurnal Ilmiah Indonesia, 2025, v. 5, n. 6, p. 1759, doi. 10.59141/cerdika.v5i6.2669

By:

Rani Juli Antari, Ni Komang

Publication type:

Article

Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report.

Published in:

2025

By:

Ramadhan, Abdullah;
Troug, Anita;
Yacyshyn, Elaine;
Gniadecki, Robert

Publication type:

Case Study

Enhancing Clinical Outcomes and Survival in Hospitalized Multiple Sclerosis Patients with COVID-19: Challenges of Antiviral Therapy.

Published in:

Physiology & Pharmacology, 2025, v. 29, n. 2, p. 111, doi. 10.61186/phypha.29.2.111

By:

Maghbooli, Zhila;
Kasaeian, Amir;
Fattahi, Mohammad Reza;
Varzandi, Tarlan;
Hamtaeigashi, Sara;
Mohammadnabi, Sara;
Sahraian, Mohammad Ali

Publication type:

Article

Pseudorabies Virus IE180 Inhibits Virus Replication by Activating the Type I Interferon Pathway.

Published in:

Microorganisms, 2025, v. 13, n. 6, p. 1397, doi. 10.3390/microorganisms13061397

By:

Zheng, Feiyang;
Song, Jingjing;
Chen, Xuan;
Xing, Dongyue;
Bai, Rulan;
Cheng, Changyong;
Yuan, Jin;
Zhang, Rui

Publication type:

Article

IL‐4, IL‐15, and Type I Interferon Orchestrate the Shaping of the Heterogeneity of Virtual Memory CD8 T Cells.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451765

By:

Park, Hi Jung;
Choi, Sung Min;
Choi, Eun A.;
Boo, Hyun Ji;
Lee, Jae Il;
Jung, Kyeong Cheon

Publication type:

Article

Interferons and Toxoplasma gondii shape PD-L1 regulation in retinal barrier cells: the critical role of proteases.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1607247

By:

Geiller, Benjamin;
Cevallos, Camila;
Tsybenko, Iuliia;
Arnoux, Lydia;
Felder-Schmittbuhl, Marie-Paule;
Pfaff, Alexander W.

Publication type:

Article

Transcriptional profiling of Chlamydia trachomatis and its host in an ex vivo endocervical primary cell culture system using dual RNA sequencing.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1613922

By:

Olagoke, Olusola;
Chittaranjan, Siddharth;
Dean, Deborah

Publication type:

Article

EphB2-mediated ephrin-B reverse signaling on microglia drives an anti-viral, but inflammatory and neurotoxic response associated with HIV.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03481-9

By:

Koury, Jeffrey;
Singh, Hina;
Sutley-Koury, Samantha N.;
Fok, Dominic;
Qiu, Xinru;
Maung, Ricky;
Gelman, Benjamin B.;
Ethell, Iryna M.;
Kaul, Marcus

Publication type:

Article

SARS-CoV-2 ORF7a Protein Impedes Type I Interferon-Activated JAK/STAT Signaling by Interacting with HNRNPA2B1.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5536, doi. 10.3390/ijms26125536

By:

Wen, Yujie;
Li, Chaochao;
Tang, Tian;
Luo, Chao;
Lu, Shan;
Lyu, Na;
Li, Yongxi;
Wang, Rong

Publication type:

Article

Inhibitory effects of a hot-water extract of cumin fruit on influenza A virus infection.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326423

By:

Al Sufian Shuvo, Abdullah;
Maekawa, Yoshihiko;
Kassai, Masahiro;
Kawahara, Takeshi

Publication type:

Article

Finetuning Type I Interferon Signaling to Enhance T Cell Immunity in HIV Infection.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 774, doi. 10.3390/v17060774

By:

Mu, Wenli;
Kedia, Nandita;
Zhen, Anjie

Publication type:

Article

Interaction of TLR- IFN and HLA polymorphisms on susceptibility of chronic HBV infection in Southwest Han Chinese.

Published in:

Liver International, 2015, v. 35, n. 8, p. 1941, doi. 10.1111/liv.12756

By:

He, Dengming;
Tao, Shiqi;
Guo, Shimin;
Li, Maoshi;
Wu, Junqiu;
Huang, Hongfei;
Guo, Xinwu;
Yan, Guohua;
Zhu, Peng;
Wang, Yuming

Publication type:

Article

Tackling COVID‐19 Using Antiviral Nanocoating's—Recent Progress and Future Challenges.

Published in:

Particle & Particle Systems Characterization, 2023, v. 40, n. 1, p. 1, doi. 10.1002/ppsc.202200154

By:

Ghosal, Krishanu

Publication type:

Article

Mutations in the non-structural protein coding region regulate gene expression from replicon RNAs derived from Venezuelan equine encephalitis virus.

Published in:

Biotechnology Letters, 2023, v. 45, n. 8, p. 1029, doi. 10.1007/s10529-023-03379-7

By:

Lin, Guibin;
Zhang, Yuan

Publication type:

Article

MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway.

Published in:

Biotechnology Letters, 2021, v. 43, n. 7, p. 1357, doi. 10.1007/s10529-021-03115-z

By:

Huang, Baizhi;
Chen, Haiping;
Zheng, Yanbing

Publication type:

Article

Circular RNA-0007059 protects cell viability and reduces inflammation in a nephritis cell model by inhibiting microRNA-1278/SHP-1/STAT3 signaling.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00372-6

By:

Guo, Peng-Wei;
Huang, Hai-Ting;
Ma, Jing;
Zuo, Yao;
Huang, Dan;
He, Lin-Lin;
Wan, Zi-Ming;
Chen, Cheng;
Yang, Fa-Fen;
You, Yan-Wu

Publication type:

Article

IFI27, a potential candidate molecular marker for primary Sjogren's syndrome.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 5, p. 1949, doi. 10.1007/s10067-025-07409-9

By:

Yang, Yiying;
Zhang, Ying;
Liu, Ke;
Liu, Meidong;
Zhang, Huali;
Guo, Muyao

Publication type:

Article

Isolated cutaneous panniculitis in Sjögren's disease exacerbated by COVID-19 illness.

Published in:

2024

By:

Phan, Kevin;
Chou, Shaun;
Lee, Adrian Y. S.

Publication type:

Case Study

Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 8, p. 2403, doi. 10.1007/s10067-024-07046-8

By:

Liu, Mengyao;
Wang, Shenglong;
Liang, Yujiao;
Fan, Yongsheng;
Wang, Weijie

Publication type:

Article

Potential relevance of type I interferon-related biomarkers for the management of polygenic autoimmune rheumatic diseases with childhood onset.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 7, p. 1733, doi. 10.1007/s10067-023-06645-1

By:

Ciurtin, Coziana

Publication type:

Article

Identification of potential biomarkers for systemic lupus erythematosus by integrated analysis of gene expression and methylation data.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 5, p. 1423, doi. 10.1007/s10067-022-06495-3

By:

Zhang, Wenjing;
Liang, Guixin;
Zhou, Huifeng;
Zeng, Xuedan;
Zhang, Zhiwen;
Xu, Xia;
Lai, Kuan

Publication type:

Article

Coexpression network analysis coupled with connectivity map database mining reveals novel genetic biomarkers and potential therapeutic drugs for polymyositis.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 6, p. 1719, doi. 10.1007/s10067-021-06035-5

By:

Wang, Kai;
Zhu, Rujie;
Li, Ju;
Zhang, Zhongyuan;
Wen, Xin;
Chen, Hongwei;
Sun, Lingyun

Publication type:

Article

Bioinformatics analyses of gene expression profile identify key genes and functional pathways involved in cutaneous lupus erythematosus.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 2, p. 437, doi. 10.1007/s10067-021-05913-2

By:

Gao, Zhen-yu;
Su, Lin-chong;
Wu, Qing-chao;
Sheng, Jiao-e;
Wang, Yun-long;
Dai, Yu-fang;
Chen, An-ping;
He, San-shan;
Huang, Xia;
Yan, Guo-qing

Publication type:

Article

Interferon-directed therapies for the treatment of systemic lupus erythematosus: a critical update.

Published in:

Clinical Rheumatology, 2021, v. 40, n. 8, p. 3027, doi. 10.1007/s10067-020-05526-1

By:

Chaichian, Yashaar;
Strand, Vibeke

Publication type:

Article

Variability in Susceptibility to Type I Interferon Response and Subgenomic RNA Accumulation Between Clinical Isolates of Dengue and Zika Virus From Oaxaca Mexico Correlate With Replication Efficiency in Human Cells and Disease Severity.

Published in:

2024

By:

Bustos-Arriaga, Jose;
Díaz-Lima, Nallely;
Aguilar-Ruíz, Sergio Roberto;
Castro-Jiménez, Tannya Karen

Publication type:

Abstract