Works matching DE "TUMOR suppressor proteins"

Results: 3356

Correlation between the DNA methylation and gene expression of IGFBP5 in breast cancer.

Published in:

Breast Disease, 2016, v. 36, n. 4, p. 123, doi. 10.3233/BD-160234

By:

Karabulut, Sevgi;
Kaya, Zehra;
Amuran, Gökçe Gūllū;
Peker, Irem;
Özmen, Tolga;
Gūllūog¯lu, Bahadır M.;
Kaya, Handan;
Erzik, Can;
Ōzer, Ayşe;
Akkiprik, Mustafa

Publication type:

Article

TGF-β in Mammary Gland Development and Breast Cancer.

Published in:

Breast Disease, 2003, v. 18, n. 1, p. 61, doi. 10.3233/BD-2003-18107

By:

Serra, Rosa;
Crowley, Michael R.

Publication type:

Article

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology?

Published in:

Journal of Parkinson's Disease, 2017, v. 7, n. 1, p. 13, doi. 10.3233/JPD-160989

By:

Truban, Dominika;
Xu Hou;
Caulfield, Thomas R.;
Fiesel, Fabienne C.;
Springer, Wolfdieter

Publication type:

Article

p53 in colorectal cancer: from a master player to a privileged therapy target.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06566-4

By:

Yan, Sicheng;
Zhan, Fuyuan;
He, Yuxuan;
Zhu, Yuehong;
Ma, Zhihong

Publication type:

Article

RETRACTED: Effects of Gallotannin-Enriched Extract of Galla Rhois on the Activation of Apoptosis, Cell Cycle Arrest, and Inhibition of Migration Ability in LLC1 Cells and LLC1 Tumors.

Published in:: Pathology & Oncology Research, 2025, p. 1, doi. 10.3389/pore.2021.588084
Publication type:: Article

Study on the mechanism of Tongjing Yihao decoction in the treatment of oligoasthenozoospermia based on network pharmacology and molecular docking.

Published in:

Chinese Journal of Bioprocess Engineering, 2025, v. 23, n. 3, p. 301, doi. 10.3969/j.issn.1672-3678.2025.03.008

By:

TIAN Zhaohui;
LIU Jia;
XIE Weiquan;
XIA Wei;
YANG Chao;
ZHANG Jinhong;
ZENG Qingqi

Publication type:

Article

Elucidating the anticancerous efficacy of genistein via modulating HPV (E7 and E6) oncogenes expression and apoptotic induction in cervical cancer cells.

Published in:

Biotechnology & Applied Biochemistry, 2025, v. 72, n. 3, p. 709, doi. 10.1002/bab.2691

By:

Pandey, Pratibha;
Ramniwas, Seema;
Pandey, Shivam;
Lakhanpal, Sorabh;
Ballal, Suhas;
Kumar, Sanjay;
Bhat, Mahakshit;
Sharma, Shilpa;
Kumar, M. Ravi;
Khan, Fahad

Publication type:

Article

Selinexor in acute myeloid leukemia: therapeutic applications and current challenges.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1602911

By:

Qie, Ziyu;
Ma, Li;
Tan, Jie;
Peng, Xiaochun

Publication type:

Article

Circular Nucleic Acids Act as an Oncogenic MicroRNA Sponge to Inhibit Hepatocellular Carcinoma Progression.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1171, doi. 10.3390/biomedicines13051171

By:

Zhang, Qianyi;
Sun, Pengcheng;
Hu, Guang;
Yu, Xuanyao;
Zhang, Wen;
Feng, Xuan;
Yu, Lan;
Zhang, Pengfei

Publication type:

Article

Mechanistic Role of the Mdm2/MdmX Lid Domain in Regulating Their Interactions with p53.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 642, doi. 10.3390/biom15050642

By:

Wei, Qiuyin;
Li, Chenqi;
Tang, Yibing;
Bai, Jinping;
Li, Wang;
Liu, Jidong;
Su, Zhengding;
Cheng, Xiyao

Publication type:

Article

Melanoma Glycome Regulates the Pro-Oncogenic Properties of Extracellular Galectin-3.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4882, doi. 10.3390/ijms26104882

By:

Mohammed, Norhan B. B.;
Shil, Rajib K.;
Dimitroff, Charles J.

Publication type:

Article

Multi-Omics Analysis of the Epigenetic Effects of Inflammation in Murine Type II Pneumocytes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4692, doi. 10.3390/ijms26104692

By:

Fernandez, Jenna A.;
Han, Qiyuan;
Rajczewski, Andrew T.;
Kono, Thomas;
Weirath, Nicholas A.;
Lee, Alexander S.;
Rahim, Abdur;
Tretyakova, Natalia Y.

Publication type:

Article

Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes.

Published in:

IUBMB Life, 2025, v. 77, n. 5, p. 1, doi. 10.1002/iub.70018

By:

Torices, Leire;
Nunes‐Xavier, Caroline E.;
Pulido, Rafael

Publication type:

Article

PTEN is a protein tyrosine phosphatase for IRS1.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 522, doi. 10.1038/nsmb.2828

By:

Shi, Yuji;
Wang, Junru;
Chandarlapaty, Sarat;
Cross, Justin;
Thompson, Craig;
Rosen, Neal;
Jiang, Xuejun

Publication type:

Article

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 916, doi. 10.1038/nsmb.2353

By:

Cui, Gaofeng;
Park, Sungman;
Badeaux, Aimee I;
Kim, Donghwa;
Lee, Joseph;
Thompson, James R;
Yan, Fei;
Kaneko, Satoshi;
Yuan, Zengqiang;
Botuyan, Maria Victoria;
Bedford, Mark T;
Cheng, Jin Q;
Mer, Georges

Publication type:

Article

A glutamate switch controls voltage-sensitive phosphatase function.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 633, doi. 10.1038/nsmb.2289

By:

Liu, Lijun;
Kohout, Susy C;
Xu, Qiang;
Müller, Simone;
Kimberlin, Christopher R;
Isacoff, Ehud Y;
Minor, Daniel L

Publication type:

Article

Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 10, p. 1086, doi. 10.1038/nsmb.2114

By:

Hagn, Franz;
Lagleder, Stephan;
Retzlaff, Marco;
Rohrberg, Julia;
Demmer, Oliver;
Richter, Klaus;
Buchner, Johannes;
Kessler, Horst

Publication type:

Article

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 12, p. 1461, doi. 10.1038/nsmb.1943

By:

Badie, Sophie;
Escandell, Jose M.;
Bouwman, Peter;
Carlos, Ana Rita;
Thanasoula, Maria;
Gallardo, Maria M.;
Suram, Anitha;
Jaco, Isabel;
Benitez, Javier;
Herbig, Utz;
Blasco, Maria A.;
Jonkers, Jos;
Tarsounas, Madalena

Publication type:

Article

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1263, doi. 10.1038/nsmb.1905

By:

Thorslund, Tina;
McIlwraith, Michael J.;
Compton, Sarah A.;
Lekomtsev, Sergey;
Petronczki, Mark;
Griffith, Jack D.;
West, Stephen C.

Publication type:

Article

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1260, doi. 10.1038/nsmb.1904

By:

Jie Liu;
Doty, Tammy;
Gibson, Bryan;
Heyer, Wolf-Dietrich

Publication type:

Article

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1051, doi. 10.1038/nsmb.1868

By:

Hirschi, Alexander;
Cecchini, Matthew;
Steinhardt, Rachel C;
Schamber, Michael R;
Dick, Frederick A;
Rubin, Seth M

Publication type:

Article

The C terminus of p53 binds the N-terminal domain of MDM2.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 8, p. 982, doi. 10.1038/nsmb.1872

By:

Poyurovsky, Masha V.;
Katz, Chen;
Laptenko, Oleg;
Beckerman, Rachel;
Lokshin, Maria;
Jinwoo Ahn;
Byeon, In-Ja L.;
Gabizon, Ronen;
Mattia, Melissa;
Zupnick, Andrew;
Brown, Lewis M.;
Friedler, Assaf;
Prives, Carol

Publication type:

Article

Research highlights.

Published in:: Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 678, doi. 10.1038/nsmb0610-678
Publication type:: Article

Four p(53)s in a pod.

Published in:

2010

By:

Chitayat, Seth;
Arrowsmith, Cheryl H.

Publication type:

Opinion

Cabin1 restrains p53 activity on chromatin.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 910, doi. 10.1038/nsmb.1657

By:

Hyonchol Jang;
Soo-Youn Choi;
Eun-Jung Cho;
Hong-Duk Youn

Publication type:

Article

Molecular basis of Pirh2-mediated p53 ubiquitylation.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1334, doi. 10.1038/nsmb.1521

By:

Sheng, Yi;
Laister, Rob C.;
Lemak, Alexander;
Wu, Bin;
Tai, Elizabeth;
Duan, Shili;
Lukin, Jonathan;
Sunnerhagen, Maria;
Srisailam, Sampath;
Karra, Murthy;
Benchimol, Sam;
Arrowsmith, Cheryl H.

Publication type:

Article

When loose ends finally meet.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1241, doi. 10.1038/nsmb1208-1241

By:

Huen, Michael S. Y.;
Chen, Junjie

Publication type:

Article

Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 215, doi. 10.1038/nsmb1208

By:

Xia, Mingxuan;
Land, Hartmut

Publication type:

Article

Research highlights.

Published in:: Nature Structural & Molecular Biology, 2007, v. 14, n. 2, p. 102, doi. 10.1038/nsmb0207-102
Publication type:: Article

Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology.

Published in:

2006

By:

Smith, Thomas G.;
Brooks, Jerome T.;
Balanos, George M.;
Lappin, Terence R.;
Layton, D. Mark;
Leedham, Dawn L.;
Chun Liu;
Maxwell, Patrick H.;
McMullin, Mary F.;
McNamara, Christopher J.;
Percy, Melanie J.;
Pugh, Christopher W.;
Ratcliffe, Peter J.;
Talbot, Nick P.;
Treacy, Marilyn;
Robbins, Peter A.;
Liu, Chun

Publication type:

journal article

mRNA sequencing analysis and growth inhibitory effects of palbociclib on cell lines from canine histiocytic proliferative disorders.

Published in:

Veterinary & Comparative Oncology, 2022, v. 20, n. 3, p. 587, doi. 10.1111/vco.12812

By:

Hirabayashi, Miyuki;
Chambers, James K.;
Tani, Akiyoshi;
Tomiyasu, Hirotaka;
Motegi, Tomoki;
Rimpo, Kenji;
Nakayama, Hiroyuki;
Uchida, Kazuyuki

Publication type:

Article

Total Synthesis of Cryptocaryol A by Enantioselective Iridium-Catalyzed Alcohol C−H Allylation.

Published in:

Angewandte Chemie, 2016, v. 128, n. 16, p. 5133, doi. 10.1002/ange.201600591

By:

Perez, Felix;
Waldeck, Andrew R.;
Krische, Michael J.

Publication type:

Article

The Development of Fluorescent Probes for Visualizing Intracellular Hydrogen Polysulfides.

Published in:

Angewandte Chemie, 2015, v. 127, n. 47, p. 14167, doi. 10.1002/ange.201506887

By:

Chen, Wei;
Rosser, Ethan W.;
Matsunaga, Tetsuro;
Pacheco, Armando;
Akaike, Takaaki;
Xian, Ming

Publication type:

Article

Epidithiodiketopiperazine Biosynthesis: A Four-Enzyme Cascade Converts Glutathione Conjugates into Transannular Disulfide Bridges.

Published in:

Angewandte Chemie, 2013, v. 125, n. 42, p. 11298, doi. 10.1002/ange.201305059

By:

Scharf, Daniel H.;
Chankhamjon, Pranatchareeya;
Scherlach, Kirstin;
Heinekamp, Thorsten;
Willing, Karsten;
Brakhage, Axel A.;
Hertweck, Christian

Publication type:

Article

Protein kinase C iota (PKCι) and pVHL are both needed for lysosomal degradation of α5 integrin in renal carcinoma cells.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10272-1

By:

Schurr, Alissa F.;
Dave, Chandni S.;
Shah, Prachi J.;
Meth, Jennifer L.;
Jaramillo, Alexandria S.;
Bartley, Kelly;
Schoenfeld, Alan R.

Publication type:

Article

Association analysis of miRNA-146a and miRNA-196a polymorphism with breast cancer risk in Khyber Pakhtunkhwa, Pakistan: a preliminary study.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09765-2

By:

Hina, Gul I.;
Khan, Najeeb Ullah;
Muntaha, Sidra Tul;
Ullah, Asad;
Khan, Sherhayat;
Alanzi, Abdullah R.;
Ali, Ijaz;
Chen, Tianhui

Publication type:

Article

The scaffold protein disabled 2 (DAB2) and its role in tumor development and progression.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09653-9

By:

Pandya, Disha V.;
Parikh, Rajsi V.;
Gena, Ruhanahmed M.;
Kothari, Nirjari R.;
Parekh, Priyajeet S.;
Chorawala, Mehul R.;
Jani, Maharsh A.;
Yadav, Mayur R.;
Shah, Palak A.

Publication type:

Article

p53 expression status is a significant molecular marker in predicting the time to endocrine therapy failure in recurrent breast cancer: a cohort study.

Published in:

International Journal of Clinical Oncology, 2006, v. 11, n. 6, p. 426, doi. 10.1007/s10147-006-0601-6

By:

Kai, Kazuharu;
Nishimura, Reiki;
Arima, Nobuyuki;
Miyayama, Haruhiko;
Iwase, Hirotaka

Publication type:

Article

Recent advances in ideas on the molecular pathology and clinical aspects of Von Hippel-Lindau disease.

Published in:

International Journal of Clinical Oncology, 2004, v. 9, n. 4, p. 283, doi. 10.1007/s10147-004-0415-3

By:

Shuin, Taro;
Yamazaki, Ichiro;
Tamura, Kenji;
Kamada, Masayuki;
Ashida, Shingo

Publication type:

Article

Parkin exerts the tumor‐suppressive effect through targeting mitochondria.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 4, p. 855, doi. 10.1002/med.21938

By:

Sun, Xin;
Ye, Guiqin;
Mai, Yuanyuan;
Shu, Yuhan;
Wang, Lei;
Zhang, Jianbin

Publication type:

Article

Mechanism of activation and the rewired network: New drug design concepts.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 2, p. 770, doi. 10.1002/med.21863

By:

Nussinov, Ruth;
Zhang, Mingzhen;
Maloney, Ryan;
Tsai, Chung‐Jung;
Yavuz, Bengi Ruken;
Tuncbag, Nurcan;
Jang, Hyunbum

Publication type:

Article

Insights into the molecular features of the von Hippel–Lindau-like protein.

Published in:

Amino Acids, 2019, v. 51, n. 10-12, p. 1461, doi. 10.1007/s00726-019-02781-8

By:

Minervini, Giovanni;
Quaglia, Federica;
Tabaro, Francesco;
Tosatto, Silvio C. E.

Publication type:

Article

Conformational stabilization of FOX-DNA complex architecture to sensitize prostate cancer chemotherapy.

Published in:

Amino Acids, 2017, v. 49, n. 7, p. 1247, doi. 10.1007/s00726-017-2426-1

By:

Chen, Bin;
Wang, Huiqiang;
Wu, Zhun;
Duan, Bo;
Bai, Peide;
Zhang, Kaiyan;
Li, Wei;
Zheng, Jiaxin;
Xing, Jinchun

Publication type:

Article

Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.

Published in:

Amino Acids, 2011, v. 41, n. 4, p. 863, doi. 10.1007/s00726-010-0497-3

By:

Berge, Gisle;
Mælandsmo, Gunhild

Publication type:

Article

S100A2 in cancerogenesis: a friend or a foe?

Published in:

Amino Acids, 2011, v. 41, n. 4, p. 849, doi. 10.1007/s00726-010-0623-2

By:

Wolf, Susann;
Haase-Kohn, Cathleen;
Pietzsch, Jens

Publication type:

Article

Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds.

Published in:

Amino Acids, 2011, v. 41, n. 1, p. 29, doi. 10.1007/s00726-010-0578-3

By:

Pinto, John;
Lee, Jeong-In;
Sinha, Raghu;
MacEwan, Melanie;
Cooper, Arthur

Publication type:

Article

Structure and function of MDM2 and MDM4 in health and disease.

Published in:

2025

By:

Zhu, Ivy Yiyi;
Lloyd, Alec;
Critchley, William R.;
Saikia, Queen;
Jade, Dhananjay;
Divan, Aysha;
Zeqiraj, Elton;
Harrison, Michael A.;
Brown, Christopher J.;
Ponnambalam, Sreenivasan

Publication type:

Literature Review

mCSM: predicting the effects of mutations in proteins using graph-based signatures.

Published in:

Bioinformatics, 2014, v. 30, n. 3, p. 335, doi. 10.1093/bioinformatics/btt691

By:

Pires, Douglas E. V.;
Ascher, David B.;
Blundell, Tom L.

Publication type:

Article

Revisiting the Role of CD63 as Pro‐Tumorigenic or Anti‐Tumorigenic Tetraspanin in Cancers and its Theragnostic Implications.

Published in:

Advanced Biology, 2023, v. 7, n. 7, p. 1, doi. 10.1002/adbi.202300078

By:

Dey, Saurabh;
Basu, Soumya;
Ranjan, Amit

Publication type:

Article

Glucose deprivation impairs hypoxia-inducible factor-1α synthesis.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01484-1

By:

Hubert, Mia;
Stuart, Sarah;
Ohh, Michael

Publication type:

Article