Works matching DE "TUBERIN"

Results: 34

Importance of tuberin in carcinogenesis (Review).

Published in:

Oncology Letters, 2017, v. 14, n. 3, p. 2598, doi. 10.3892/ol.2017.6490

By:

Mingwei Jin;
Qi An;
Lei Wang

Publication type:

Article

The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210612

By:

Fidalgo da Silva, Elizabeth;
Botsford, Sabrina;
Dare-Shih, Jessica;
Hanna, Miranda A.;
Porter, Lisa A.

Publication type:

Article

Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197105

By:

Himes, Blanca E.;
Obraztsova, Kseniya;
Lian, Lurong;
Shumyatcher, Maya;
Rue, Ryan;
Atochina-Vasserman, Elena N.;
Hur, Stella K.;
Bartolomei, Marisa S.;
Evans, Jilly F.;
Krymskaya, Vera P.

Publication type:

Article

Suppressed Expression of Autophagosomal Protein LC3 in Cortical Tubers of Tuberous Sclerosis Complex.

Published in:

Brain Pathology, 2013, v. 23, n. 3, p. 254, doi. 10.1111/j.1750-3639.2012.00634.x

By:

Miyahara, Hiroaki;
Natsumeda, Manabu;
Shiga, Atsushi;
Aoki, Hiroshi;
Toyoshima, Yasuko;
Zheng, Yingjun;
Takeuchi, Ryoko;
Murakami, Hiroatsu;
Masuda, Hiroshi;
Kameyama, Shigeki;
Izumi, Tatsuro;
Fujii, Yukihiko;
Takahashi, Hitoshi;
Kakita, Akiyoshi

Publication type:

Article

Diseases of the nervous system: The complexity of compensation.

Published in:

Nature Medicine, 2013, v. 19, n. 10, p. 1220, doi. 10.1038/nm.3377

By:

Chmielnicki, Eva

Publication type:

Article

Tuberin and p27 expression in breast cancer patients with or without BRCA germline mutations.

Published in:

Journal of Cancer Research & Clinical Oncology, 2013, v. 139, n. 8, p. 1349, doi. 10.1007/s00432-013-1443-z

By:

Dressler, Anne;
Hudelist, Gernot;
Fink-Retter, Anneliese;
Gschwantler-Kaulich, Daphne;
Pfeiler, Georg;
Rosner, Margit;
Hengstschläger, Markus;
Singer, Christian

Publication type:

Article

Cerebellar lesions are associated with TSC2 mutations in tuberous sclerosis complex: a retrospective record review study.

Published in:

2017

By:

Boronat, Susana;
Thiele, Elizabeth Anne;
Caruso, Paul

Publication type:

journal article

Absence of subependymal nodules in patients with tubers suggests possible neuroectodermal mosaicism in tuberous sclerosis complex.

Published in:

Developmental Medicine & Child Neurology, 2014, v. 56, n. 12, p. 1207, doi. 10.1111/dmcn.12523

By:

Boronat, Susana;
Caruso, Paul;
Thiele, Elizabeth A

Publication type:

Article

Careful clinical observation continues to improve understanding of the phenotype in individuals with tuberous sclerosis complex.

Published in:

Developmental Medicine & Child Neurology, 2014, v. 56, n. 12, p. 1134, doi. 10.1111/dmcn.12537

By:

Jansen, Anna C

Publication type:

Article

Subependymal giant cell astrocytoma: current concepts, management, and future directions.

Published in:

Child's Nervous System, 2014, v. 30, n. 4, p. 561, doi. 10.1007/s00381-014-2383-x

By:

Ouyang, Taohui;
Zhang, Na;
Benjamin, Thomas;
Wang, Long;
Jiao, Jiantong;
Zhao, Yiqing;
Chen, Jian

Publication type:

Article

Rapamycin has a beneficial effect on controlling epilepsy in children with tuberous sclerosis complex: results of 7 children from a cohort of 86.

Published in:

Child's Nervous System, 2014, v. 30, n. 2, p. 227, doi. 10.1007/s00381-013-2185-6

By:

Canpolat, Mehmet;
Per, Huseyin;
Gumus, Hakan;
Yikilmaz, Ali;
Unal, Ekrem;
Patiroglu, Turkan;
Cinar, Levent;
Kurtsoy, Ali;
Kumandas, Sefer

Publication type:

Article

Lymphangioleiomyomatosis: differential diagnosis and optimal management.

Published in:

Therapeutics & Clinical Risk Management, 2014, v. 10, p. 691, doi. 10.2147/TCRM.S50784

By:

Kai-Feng Xu;
Bee Hong Lo

Publication type:

Article

Tuberous Sclerosis Presenting With Acute Kidney Failure, Pyelonephritis, and Polycystic Kidney Disease.

Published in:

Iranian Journal of Kidney Diseases, 2014, v. 8, n. 4, p. 336

By:

Mohkam, Masoumeh;
Shohadaii, Shirin;
Kompani, Farshid;
Aghadoost, Hamid Reza;
Hojati, Seyed Ali;
Esfandiar, Nasrin

Publication type:

Article

Clinical manifestations of tuberous sclerosis complex.

Published in:

Eastern Journal of Medicine, 2013, v. 18, n. 2, p. 52

By:

Atay, Ahmet Engin;
Akbas, Halit;
Sakar, Nafi;
Pasa, Semir;
Ari, Seyhmus;
Ekin, Nazim

Publication type:

Article

First comprehensive TSC1/TSC2 mutational analysis in Mexican patients with Tuberous Sclerosis Complex reveals numerous novel pathogenic variants.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62759-5

By:

Reyna-Fabián, Miriam E.;
Hernández-Martínez, Nancy L.;
Alcántara-Ortigoza, Miguel A.;
Ayala-Sumuano, Jorge T.;
Enríquez-Flores, Sergio;
Velázquez-Aragón, José A.;
Varela-Echavarría, Alfredo;
Todd-Quiñones, Carlos G.;
González-del Angel, Ariadna

Publication type:

Article

Upregulation of C/EBPβ and TSC2 by an HDAC inhibitor CG200745 protects heart from DOCA‐induced hypertrophy.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2019, v. 46, n. 3, p. 226, doi. 10.1111/1440-1681.13022

By:

Lee, Eunjo;
Lee, Hae‐Ahm;
Kim, Mina;
Do, Ga young;
Cho, Hyun‐Min;
Kim, Gun Jik;
Jung, Hanna;
Song, Jung Hup;
Cho, Joong Myung;
Kim, Inkyeom

Publication type:

Article

Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex:: Considerations for Surgical or Pharmacotherapeutic Intervention.

Published in:

Journal of Child Neurology, 2014, v. 29, n. 11, p. 1562, doi. 10.1177/0883073813501870

By:

Wheless, James W.;
Klimo, Paul

Publication type:

Article

Congenital Segmental Lymphedema in Tuberous Sclerosis Complex With Associated Subependymal Giant Cell Astrocytomas Treated with Mammalian Target of Rapamycin Inhibitors.

Published in:

Journal of Child Neurology, 2014, v. 29, n. 9, p. NP54, doi. 10.1177/0883073813499969

By:

Prato, Giulia;
Mancardi, Maria Margherita;
Baglietto, Maria Giuseppina;
Janis, Sara;
Vercellino, Nadia;
Rossi, Andrea;
Consales, Alessandro;
Raso, Alessandro;
Garrè, Maria Luisa

Publication type:

Article

The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models.

Published in:

Mammalian Genome, 2014, v. 25, n. 9/10, p. 401, doi. 10.1007/s00335-014-9514-2

By:

Joost, Hans-Georg;
Schürmann, Annette

Publication type:

Article

Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05927

By:

Masatoshi Shiono;
Toshiyuki Kobayashi;
Riichi Takahashi;
Masatsugu Ueda;
Chikashi Ishioka;
Okio Hino

Publication type:

Article

Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex.

Published in:

Biologics: Targets & Therapy, 2013, v. 7, p. 211, doi. 10.2147/BTT.S25095

By:

Franz, David Neal

Publication type:

Article

Evidence of Ambiguous Differentiation and mTOR Pathway Dysregulation in Subependymal Giant Cell Astrocytoma.

Published in:

Turkish Journal of Pathology, 2012, v. 28, n. 2, p. 95, doi. 10.5146/tjpath.2012.01107

By:

Barrows, Brad D.;
Rutkowski, Martin J.;
Gültekin, Şakir Humayun;
Parsa, Andrew T.;
Tihan, Tarik

Publication type:

Article

mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0152628

By:

Manabu Taneike;
Kazuhiko Nishida;
Shigemiki Omiya;
Zarrinpashneh, Elham;
Tomofumi Misaka;
Rika Kitazume-Taneike;
Ruth Austin;
Minoru Takaoka;
Osamu Yamaguchi;
Gambello, Michael J.;
Shah, Ajay M.;
Kinya Otsu

Publication type:

Article

Tuberous-sclerosis complex-related cell signaling in the pathogenesis of lung cancer.

Published in:

Diagnostic Pathology, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1746-1596-9-48

By:

Fuchs, Angela;
König, Katharina;
Heukamp, Lukas C.;
Fassunke, Jana;
Kirfel, Jutta;
Huss, Sebastian;
Becker, Albert J.;
Büttner, Reinhard;
Majores, Michael

Publication type:

Article

Identification of a novel TSC2 c.3610G > A, p.G1204R mutation contribute to aberrant splicing in a patient with classical tuberous sclerosis complex: a case report.

Published in:

2018

By:

Zhang, Ruixiao;
Wang, Jianhong;
Wang, Qing;
Han, Yue;
Liu, Xuejun;
Bottillo, Irene;
Lang, Yanhua;
Shao, Leping

Publication type:

Case Study

Subependymal giant cell astrocytoma, hereditary versus solitary: clinical, morphological, and immunophenotypic characterization.

Published in:

Revista Mexicana de Neurociencia, 2024, v. 25, n. 3, p. 66, doi. 10.24875/RMN.23000074

By:

Calderón-Garcidueñas, Ana L.;
Piña-Ballantyne, Steven A.

Publication type:

Article

May the Force move you: TSC-ing the mechanical activation of mTOR.

Published in:

Journal of Physiology, 2013, v. 591, n. 18, p. 4369, doi. 10.1113/jphysiol.2013.260216

By:

West, Daniel W. D.;
Baar, Keith

Publication type:

Article

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury.

Published in:

Diabetes, 2013, v. 62, n. 8, p. 2935, doi. 10.2337/db12-1504

By:

Eid, Assaad A.;
Ford, Bridget M.;
Bhandary, Basant;
de Cassia Cavaglieri, Rita;
Block, Karen;
Barnes, Jeffrey L.;
Gorin, Yves;
Choudhury, Goutam Ghosh;
Abboud, Hanna E.

Publication type:

Article

13-year-old tuberous sclerosis patient with renal cell carcinoma associated with multiple renal angiomyolipomas developing multifocal micronodular pneumocyte hyperplasia.

Published in:

2013

By:

Ludwig Behnes, Carl;
Schütze, Gunther;
Engelke, Christoph;
Bremmer, Felix;
Gunawan, Bastian;
Radzun, Heinz-Joachim;
Schweyer, Stefan

Publication type:

Case Study

Cell signalling: A peroxisomal home for TSC.

Published in:

Nature Reviews Molecular Cell Biology, 2013, v. 14, n. 10, p. 609, doi. 10.1038/nrm3661

By:

David, Rachel

Publication type:

Article

Tuberous sclerosis complex: Recent advances in manifestations and therapy.

Published in:

International Journal of Urology, 2017, v. 24, n. 9, p. 681, doi. 10.1111/iju.13390

By:

Wataya‐Kaneda, Mari;
Uemura, Motohide;
Fujita, Kazutoshi;
Hirata, Haruhiko;
Osuga, Keigo;
Kagitani‐Shimono, Kuriko;
Nonomura, Norio

Publication type:

Article

Isolated and unilateral facial angiofibromas revealing a type 1 segmental postzygotic mosaicism of tuberous sclerosis complex with c.4949_4982del <italic>TSC2</italic> mutation.

Published in:

2018

By:

Bessis, D.;
Malinge, M.‐C.;
Girard, C.

Publication type:

Case Study

TSC on the peroxisome controls mTORC1.

Published in:

Nature Cell Biology, 2013, v. 15, n. 10, p. 1135, doi. 10.1038/ncb2849

By:

Benjamin, Don;
Hall, Michael N.

Publication type:

Article

Two novel mutations in the TSC2 gene causing severe phenotype in nervous system and skin in a patient with tuberous sclerosis complex.

Published in:

2018

By:

Cammarata‐scalisi, F.;
Vidales Moreno, C.;
Stock, F.;
Avendaño, A.;
Araque, D.;
Lacruz‐rengel, M. A.;
Diociaiuti, A.;
Bellacchio, E.;
Callea, M.

Publication type:

Case Study