Works about TROPHOBLAST

Results: 2538

Profiling the cytotoxic effects of naled and other pesticides in primary human placental cytotrophoblasts.

Published in:

Toxicological Sciences, 2025, v. 206, n. 1, p. 96, doi. 10.1093/toxsci/kfaf038

By:

Li, Lin;
Chen, Hao;
Jigmeddagva, Unurzul;
Le, Ngantu;
Kapidzic, Mirhan;
Gee, Stephanie;
Ali, Alizah;
Levan, Justine;
Person, Romane;
Chen, Jessica;
Gutierrez, Amanda M;
Okorie, Chinomnso N;
Wang, Mengjing;
Woodruff, Tracey J;
Fisher, Susan J;
Gaw, Stephanie L;
Robinson, Joshua F

Publication type:

Article

Tanshinone IIA induces oxidative stress in trophoblast cells and enhances copper dependent death.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07238-5

By:

Du, Juemeng;
Wang, Xuanyin;
Zeng, Yuerui;
Feng, Jingjing;
Yang, Lisha;
Huang, Yanxi;
Deng, Gaopi

Publication type:

Article

Pyroptosis as a therapeutic target in preeclampsia: current research and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1622550

By:

Zhu, Yongchun;
Xiang, Yuting;
Swamiappan, Sathiskumar;
Li, Zhongjun;
Peng, Xinsheng

Publication type:

Article

Mechanism of hydroxychloroquine in the treatment of obstetric antiphospholipid syndrome by inhibiting NETs-induced trophoblast pyroptosis.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10765-z

By:

Liu, Jiayue;
Xu, Mingyang;
Shen, Di;
Wang, Xietong

Publication type:

Article

Chemerin sustains the growth of spongiotrophoblast and sinusoidal trophoblast giant cells through fatty acid oxidation.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02294-9

By:

Cai, Jia xuan;
Le, Ai wen;
Han, Xin yue;
Chen, Jie;
Lei, Xiao hua;
Huang, Chen;
Zhang, Jian V.

Publication type:

Article

circFTO binding with IGF2BP2 regulates trophoblast cells proliferation, migration, and invasion while mediating m6A modification of CCAR1 mRNA in spontaneous abortion.

Published in:

BMC Molecular & Cell Biology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12860-025-00546-8

By:

Zhang, Yiwen;
Wu, Meiyao;
Lin, Xiaoling;
Lu, Bingfeng;
Chen, Xi;
Li, Qianhui;
Jiang, Yinan;
Li, Baixue;
Zhou, Dongmei;
Sheng, Xiujie

Publication type:

Article

Oropouche virus infects human trophoblasts and placenta explants.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61138-w

By:

Megli, Christina J.;
Zack, Rebecca K.;
McGaughey, Jackson J.;
Hoehl, Ryan M.;
Snisky, Taylor;
Hartman, Amy L.;
McMillen, Cynthia M.

Publication type:

Article

Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08393-1

By:

Varberg, Kaela M.;
Moreno-Irusta, Ayelen;
Novoa, Allynson;
Musser, Brynne;
Varberg, Joseph M.;
Goering, Jeremy P.;
Saadi, Irfan;
Iqbal, Khursheed;
Okae, Hiroaki;
Arima, Takahiro;
Williams III, John;
Pisarska, Margareta D.;
Soares, Michael J.

Publication type:

Article

Prenylated chalcone analog-mediated Inhibition of Toxoplasma gondii growth in human trophoblast cell line and villous explants.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08764-y

By:

Paschoalino, Marina;
Júnior, Vilson Serafim;
Soares, Otavio Henrique Locateli;
Luz, Luana Carvalho;
de Souza, Guilherme;
Rosini, Alessandra Monteiro;
Almeida, Marcos Paulo Oliveira;
Sousa, Daniel Pereira;
De Lima Júnior, Joed Pires;
Santos, Natalia Carine Lima;
Oliveira, Rafael Martins;
Damasceno, Izadora Santos;
Faria, Guilherme Vieira;
Barbosa, Matheus Carvalho;
Fernandes, Thales Alves de Melo;
Alves, Rosiane Nascimento;
Oliveira Gomes, Angelica;
Vieira Ferro, Eloisa Amália;
Teixeira, Samuel Cota;
Regasini, Luis Octavio

Publication type:

Article

Drug Metabolism and Toxicological Mechanisms.

Published in:

Toxics, 2025, v. 13, n. 6, p. 464, doi. 10.3390/toxics13060464

By:

Wang, Qi;
Zhang, Youbo;
Zhu, An

Publication type:

Article

Super-Enhancers in Placental Development and Diseases.

Published in:

Journal of Developmental Biology, 2025, v. 13, n. 2, p. 11, doi. 10.3390/jdb13020011

By:

Rosario, Gracy X.;
Brown, Samuel;
Karmakar, Subhradip;
Rumi, Mohammad A. Karim;
Nayak, Nihar R.

Publication type:

Article

Quercetin as a multifaceted therapeutic agent in recurrent pregnancy loss: Mechanisms and clinical perspectives.

Published in:

Drug Discoveries & Therapeutics, 2025, v. 19, n. 3, p. 148, doi. 10.5582/ddt.2025.01059

By:

Qing Qi;
Jing Zhou;
Jing Wang;
Yiyuan Zhou;
Hongmei Sun;
Ling Wang

Publication type:

Article

Thioredoxin-Interacting Protein (TXNIP) in Gestational Diabetes Mellitus.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 6, p. 351, doi. 10.3390/metabo15060351

By:

Kokkinopoulou, Ioanna;
Papadopoulou, Anna

Publication type:

Article

Indoleamine 2,3-Dioxygenase Regulates Placental Trophoblast Cell Invasion.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5889, doi. 10.3390/ijms26125889

By:

Kudo, Yoshiki;
Sugimoto, Jun

Publication type:

Article

MicroRNAs in Preeclampsia: An Overview of Biomarkers and Potential Therapeutic Targets.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5607, doi. 10.3390/ijms26125607

By:

Oancea, Mihaela;
Mihu, Dan;
Braicu, Cornelia;
Isachesku, Ekaterina;
Nati, Ionel-Daniel;
Boitor-Borza, Dan;
Diculescu, Doru Mihai;
Strilciuc, Stefan;
Pană, Adrian

Publication type:

Article

Cells of the Maternal–Fetal Interface May Contribute to Epidural-Related Maternal Fever After Administration of Ropivacaine: The Role of Phosphatases DUSP9 and PHLPP1.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5520, doi. 10.3390/ijms26125520

By:

Horn, Florian;
Tretter, Verena;
Kunihs, Victoria;
Wohlrab, Peter;
Trimmel, Bettina;
Janes, Kevin A.;
Djurkic, Tamara;
Mekiri, Meriem;
Knöfler, Martin;
Saleh, Leila

Publication type:

Article

A Positive Feedback Loop Involving Gcm1 and Fzd5 Directs Chorionic Branching Morphogenesis in the Placenta.

Published in:

PLoS Biology, 2013, v. 11, n. 4, p. 1, doi. 10.1371/journal.pbio.1001536

By:

Jinhua Lu;
Shuang Zhang;
Nakano, Haruo;
Simmons, David G.;
Shumin Wang;
Shuangbo Kong;
Qiang Wang;
Lianju Shen;
Zhaowei Tu;
Weixiang Wang;
Bingyan Wang;
Hongmei Wang;
Yanling Wang;
van Es, Johan H.;
Clevers, Hans;
Leone, Gustavo;
Cross, James C.;
Haibin Wang

Publication type:

Article

SUMO-Specific Protease 2 Is Essential for Modulating p53-Mdm2 in Development of Trophoblast Stem Cell Niches and Lineages.

Published in:

PLoS Biology, 2008, v. 6, n. 12, p. e310, doi. 10.1371/journal.pbio.0060310

By:

Shang-Yi Chiu;
Naoya Asai;
Costantini, Frank;
Wei Hsu

Publication type:

Article

Predictive score using umbilical vein leucine‐rich α‐2 glycoprotein as a useful biomarker for diagnosing histological chorioamnionitis in preterm infants.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 6, p. 1, doi. 10.1111/jog.16344

By:

Sotodate, Genichiro;
Serada, Satoshi;
Osakabe, Mitsumasa;
Takahashi, Fumiaki;
Matsumoto, Atsushi;
Toya, Yukiko;
Tsuchiya, Shigekuni;
Fujimoto, Minoru;
Naka, Tetsuji;
Akasaka, Manami

Publication type:

Article

NINJ1 exerts a role in the development of preeclampsia through potential regulation by the Notch1 signaling pathway.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 5, p. 1, doi. 10.1111/jog.16295

By:

Shi, Qin;
Gu, Panyun;
Tang, Yi;
Ma, Qianqian;
Xu, Yunzhao

Publication type:

Article

Exosomal‐complement system activation in preeclampsia.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 3, p. 1, doi. 10.1111/jog.16255

By:

David, M.;
Maharaj, N.;
Krishnan, A.

Publication type:

Article

Trimethylamine N‐oxide induces pyroptosis in HTR8‐S/Vneo cells through the ten‐eleven translocation 2‐cytochrome b‐reactive oxygen species pathway.

Published in:

Journal of Obstetrics & Gynaecology Research, 2025, v. 51, n. 2, p. 1, doi. 10.1111/jog.16237

By:

Liang, Lingli;
Rao, Yuzhu;
Wang, Jingjing;
Zhao, Jinli;
He, Lu;
Meng, Jun;
Wu, Peng;
Wang, Zuo

Publication type:

Article

Placental growth factor alleviates hyperglycemia‐induced trophoblast pyroptosis by regulating mitophagy.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 10, p. 1813, doi. 10.1111/jog.16050

By:

Tao, Jun;
Rao, Yuzhu;
Wang, Jingjing;
Tan, Shiming;
Zhao, Jinli;
Cao, Zitong;
He, Lu;
Meng, Jun;
Wu, Peng;
Wang, Zuo

Publication type:

Article

Current understanding of the pathogenesis of placenta accreta spectrum disorder with focus on mitochondrial function.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 6, p. 929, doi. 10.1111/jog.15936

By:

Kobayashi, Hiroshi;
Matsubara, Sho;
Yoshimoto, Chiharu;
Shigetomi, Hiroshi;
Imanaka, Shogo

Publication type:

Article

The interrelation between the high expression level of MIR34a and the trisomic abortion materials.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 5, p. 842, doi. 10.1111/jog.15913

By:

Kazancioglu, Elvin;
Tug, Esra;
Ergun, Mehmet Ali;
Kazan, Hasan Huseyin;
Karaoguz, Meral Yirmibes

Publication type:

Article

Suppression of circular RNA serum and glucocorticoid‐induced kinase 1 elevates antioxidant molecules and angiogenesis in trophoblast cells to attenuate preeclampsia via microRNA‐508‐3p to target and restrain PUM homolog 1.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 3, p. 322, doi. 10.1111/jog.15843

By:

Lu, CaiXia;
Zheng, FuMin;
Pan, LiXiao;
Han, QingFang;
Wu, JiXia;
Zhang, WenKe

Publication type:

Article

Baicalin enhances the proliferation and invasion of trophoblasts and suppresses vascular endothelial damage by modulating long non‐coding RNA NEAT1/miRNA‐205‐5p in hypertensive disorder complicating pregnancy.

Published in:

Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 9, p. 3060, doi. 10.1111/jog.14789

By:

Zhao, Lidong;
Xiong, Miao;
Liu, Yang

Publication type:

Article

Integrin β1 regulates proliferation, apoptosis, and migration of trophoblasts through activation of phosphoinositide 3 kinase/protein kinase B signaling.

Published in:

Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 7, p. 2406, doi. 10.1111/jog.14782

By:

Shu, Chang;
Han, Shumei;
Hu, Cong;
Chen, Chen;
Qu, Bo;
He, Jin;
Dong, Shuai;
Xu, Peng

Publication type:

Article

Effect of Fas/FasL signaling pathway activation in trophoblasts on recurrent spontaneous abortion.

Published in:

Journal of Obstetrics & Gynaecology Research, 2021, v. 47, n. 6, p. 1978, doi. 10.1111/jog.14742

By:

Xu, Qiuxia;
Yao, Qicen;
Huang, Sujing;
Xu, Lin;
Guan, Hongqiong

Publication type:

Article

Sex hormone‐binding globulin regulates glucose metabolism in human placental trophoblasts via cAMP/PKA/CREB1.

Published in:

Journal of Obstetrics & Gynaecology Research, 2020, v. 46, n. 11, p. 2340, doi. 10.1111/jog.14429

By:

Chi, Xinshu;
Feng, Chong;
Wang, Xiaoyan;
Jin, Zhen

Publication type:

Article

Functional variations between Mesenchymal Stem Cells of different tissue origins: A comparative gene expression profiling.

Published in:

Biotechnology Letters, 2020, v. 42, n. 7, p. 1287, doi. 10.1007/s10529-020-02898-x

By:

Sangeetha, K. N.;
Vennila, Rosy;
Secunda, R.;
Sakthivel, S.;
Pathak, Surajit;
Jeswanth, S.;
Surendran, R.

Publication type:

Article

Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00604-x

By:

Chen, Yangyang;
Liu, Xiaoxia;
Li, Lun;
He, Xiyang;
Zheng, Fanghui;
Zhang, Yang;
Gao, Hui;
Jin, Zhishan;
Wu, Di;
Wang, Qianhua;
Tao, Hui;
Zhao, Yin;
Liu, Weifang;
Zou, Li

Publication type:

Article

TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00592-4

By:

Duan, Yuhan;
Fu, Huijia;
Huang, Jiayu;
Yin, Nanlin;
Liu, Linhong;
Liu, Xiru

Publication type:

Article

LINC00240/miR-155 axis regulates function of trophoblasts and M2 macrophage polarization via modulating oxidative stress-induced pyroptosis in preeclampsia.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00531-3

By:

Wu, Hai-Ying;
liu, Kan;
Zhang, Jing-Li

Publication type:

Article

A novel role of FoxO3a in the migration and invasion of trophoblast cells: from metabolic remodeling to transcriptional reprogramming.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00522-4

By:

Chen, Hao;
Wang, Shi-Han;
Chen, Chang;
Yu, Xin-Yang;
Zhu, Jia-Nan;
Mansell, Toby;
Novakovic, Boris;
Saffery, Richard;
Baker, Philip N.;
Han, Ting-Li;
Zhang, Hua

Publication type:

Article

The long noncoding RNA MEG3 regulates Ras-MAPK pathway through RASA1 in trophoblast and is associated with unexplained recurrent spontaneous abortion.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00337-9

By:

Zhang, Jun;
Liu, Xinqiong;
Gao, Yali

Publication type:

Article

DNA Methylation‐Induced BNIP3P1 Expression Promotes Pre‐Eclampsia Progression via the miR‐128‐3p/BNIP3 Axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 6, p. 1, doi. 10.1002/jbt.70307

By:

Zhang, Qiqi;
Zheng, Haoyu;
Zhang, Muling

Publication type:

Article

CircCUL1 inhibits trophoblast cell migration and invasion and promotes cell autophagy by sponging hsa‐miR‐30e‐3p in fetal growth restriction via the ANXA1/PI3K/AKT axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 7, p. 1, doi. 10.1002/jbt.23759

By:

Yang, Tong;
Hu, Jianguo;
Zhang, Lei;
Liu, Li;
Pan, Xin;
Zhou, Yanqiu;
Wu, Yi;
Shi, Xian;
Obiegbusi, Chidera N.;
Dong, Xiaojing

Publication type:

Article

METTL14‐mediated lncRNA XIST silencing alleviates GDM progression by facilitating trophoblast cell proliferation and migration via the miR‐497‐5p/FOXO1 axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23621

By:

Li, Yanchuan;
Liu, Yanfeng;
Yao, Xiao;
Wang, Haili;
Shi, Ziyun;
He, Meiqing

Publication type:

Article

ATL1 inhibits the proliferation and invasion of trophoblast cells via inhibition of the mTOR signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 1, p. 1, doi. 10.1002/jbt.23237

By:

Zhang, Guanli;
Feng, Yan;
Wang, Min;
Liu, Xin

Publication type:

Article

Hsa_circ_0088196 suppresses trophoblast migration and invasion by the miR‐525‐5p/ABL1 axis and the PI3K/AKT signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 10, p. 1, doi. 10.1002/jbt.23150

By:

Shi, Fenglian;
Li, Li

Publication type:

Article

Upregulated lnc‐HZ02 and miR‐hz02 inhibited migration and invasion by downregulating the FAK/SRC/PI3K/AKT pathway in BPDE‐treated trophoblast cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 6, p. 1, doi. 10.1002/jbt.22757

By:

Guo, Jiarong;
Li, Rui;
Xu, Zhongyan;
Tian, Peng;
Wang, Rong;
Li, Youzhu;
Qiu, Xia;
Zou, Peng;
He, Mei;
Ao, Lin;
Liu, Qicai;
Zhang, Huidong

Publication type:

Article

Nitrofen increases total retinol levels in placenta during lung morphogenesis in the nitrofen model of congenital diaphragmatic hernia.

Published in:

Pediatric Surgery International, 2014, v. 30, n. 10, p. 1017, doi. 10.1007/s00383-014-3525-7

By:

Kutasy, Balazs;
Pes, Lara;
Friedmacher, Florian;
Paradisi, Francesca;
Puri, Prem

Publication type:

Article

Prenatal administration of retinoic acid increases the trophoblastic insulin-like growth factor 2 protein expression in the nitrofen model of congenital diaphragmatic hernia.

Published in:

Pediatric Surgery International, 2014, v. 30, n. 2, p. 137, doi. 10.1007/s00383-013-3449-7

By:

Kutasy, Balazs;
Friedmacher, Florian;
Duess, Johannes;
Puri, Prem

Publication type:

Article

Increased trophoblastic apoptosis mediated by neutrophil gelatinase-associated lipocalin (NGAL) activation in the nitrofen model of congenital diaphragmatic hernia.

Published in:

Pediatric Surgery International, 2013, v. 29, n. 1, p. 25, doi. 10.1007/s00383-012-3203-6

By:

Kutasy, Balazs;
Gosemann, Jan;
Duess, Johannes;
Puri, Prem

Publication type:

Article

Nitrofen interferes with trophoblastic expression of retinol-binding protein and transthyretin during lung morphogenesis in the nitrofen-induced congenital diaphragmatic hernia model.

Published in:

Pediatric Surgery International, 2012, v. 28, n. 2, p. 143, doi. 10.1007/s00383-011-2995-0

By:

Kutasy, Balazs;
Gosemann, Jan;
Doi, Takashi;
Fujiwara, Naho;
Friedmacher, Florian;
Puri, Prem

Publication type:

Article

Môles hydatiformes et tumeurs trophoblastiques gestationnelles.

Published in:

Oncologie (Tech Science Press), 2008, v. 10, n. 10, p. 604, doi. 10.1007/s10269-008-0974-4

By:

Golfier, F.;
Guastalla, J.;
Trillet-Lenoir, V.;
Massardier, J.;
Pavic, M.;
Schott, A.;
Raudrant, D.

Publication type:

Article

Morphological Characterization of Basally Located Uninucleate Trophoblast Cells as Precursors of Bovine Binucleate Trophoblast Giant Cells.

Published in:

Cells Tissues Organs, 2018, v. 205, n. 3, p. 151, doi. 10.1159/000489257

By:

Attiger, Jeannette;
Boos, Alois;
Klisch, Karl

Publication type:

Article

Centrosome Clustering in the Development of Bovine Binucleate Trophoblast Giant Cells.

Published in:

Cells Tissues Organs, 2017, v. 203, n. 5, p. 287, doi. 10.1159/000452271

By:

Klisch, Karl;
Schraner, Elisabeth M.;
Boos, Alois

Publication type:

Article

Different Preference of Degradome in Invasion versus Angiogenesis.

Published in:

Cells Tissues Organs, 2015, v. 200, n. 3/4, p. 181, doi. 10.1159/000381766

By:

Ghaffari-Tabrizi-Wizsy, Nassim;
Cvitic, Silvija;
Tam-amersdorfer, Carmen;
Bilban, Martin;
Majali-Martinez, alejandro;
Schramke, Karin;
Desoye, Gernot;
Hiden, Ursula

Publication type:

Article