Works matching DE "TROGLITAZONE"

Results: 50

Antitumor Effects of Troglitazone and Its Association with Peroxisome Proliferator-Activated Receptor Gamma Activation in FaDu Human Hypopharyngeal Carcinoma Cells.

Published in:

Indian Journal of Pharmaceutical Sciences, 2025, v. 87, n. 2, p. 59

By:

THU DO;
LOAN, T. T.;
LE, T. D.;
VU, P. D.;
HOON YOO

Publication type:

Article

Exploiting the predictive power of educated spheroids to detect immune-mediated idiosyncratic drug-induced liver injury: the case of troglitazone.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1378371

By:

Roux, Salomé;
Cherradi, Sara;
Hong Tuan Duong

Publication type:

Article

THE EFFECT OF TROGLITAZONE ON C-REACTIVE PROTEIN IN INDIVIDUALS WITH PREDIABETES: DATA FROM THE DIABETES PREVENTION PROGRAM.

Published in:

Journal of the Mississippi Academy of Sciences, 2018, v. 62, n. 2 Supplement, p. 275

By:

Mokthar, Khalid;
Hamadain, Elgenaid

Publication type:

Article

The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPARγ-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells.

Published in:

PPAR Research, 2012, p. 1, doi. 10.1155/2012/929052

By:

Bolden, Adrienne;
Bernard, Lynikka;
Jones, Danielle;
Akinyeke, Tunde;
Stewart, LaMonica V.

Publication type:

Article

TGFβ1 Controls PPARγ Expression, Transcriptional Potential, and Activity, in Part, through Smad3 Signaling in Murine Lung Fibroblasts.

Published in:

PPAR Research, 2012, p. 1, doi. 10.1155/2012/375876

By:

Ramirez, Allan;
Ballard, Erin N.;
Roman, Jesse

Publication type:

Article

Anti-fibrogenic effect of PPAR-γ agonists in human intestinal myofibroblasts.

Published in:

2017

By:

Jun Bon Koo;
Myeong-Ok Nam;
Younshin Jung;
Jongman Yoo;
Duk Hwan Kim;
Gwangil Kim;
Sung Jae Shin;
Kee Myung Lee;
Ki Baik Hahm;
Jong Woo Kim;
Sung Pyo Hong;
Kwang Jae Lee;
Jun Hwan Yoo;
Koo, Jun Bon;
Nam, Myeong-Ok;
Jung, Younshin;
Yoo, Jongman;
Kim, Duk Hwan;
Kim, Gwangil;
Shin, Sung Jae

Publication type:

journal article

The PPARγ agonist Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells.

Published in:

Cancer Gene Therapy, 2014, v. 21, n. 5, p. 188, doi. 10.1038/cgt.2014.16

By:

Yan, S;
Yang, X;
Chen, T;
Xi, Z;
Jiang, X

Publication type:

Article

Troglitazone suppresses glutamine metabolism through a PPAR-independent mechanism.

Published in:

Biological Chemistry, 2015, v. 396, n. 8, p. 937, doi. 10.1515/hsz-2014-0307

By:

Reynolds, Miriam R.;
Clem, Brian F.

Publication type:

Article

Phenyllactic Acid from Lactobacillus plantarum Promotes Adipogenic Activity in 3T3-L1 Adipocyte via Up-Regulation of PPAR-γ2.

Published in:

Molecules, 2015, v. 20, n. 8, p. 15359, doi. 10.3390/molecules200815359

By:

Ilavenil, Soundharrajan;
Da Hye Kim;
Arasu, Mariadhas Valan;
Srigopalram, Srisesharam;
Sivanesan, Ravikumar;
Ki Choon Choi

Publication type:

Article

Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-85708-2

By:

Dirven, Hubert;
Vist, Gunn E.;
Bandhakavi, Sricharan;
Mehta, Jyotsna;
Fitch, Seneca E.;
Pound, Pandora;
Ram, Rebecca;
Kincaid, Breanne;
Leenaars, Cathalijn H. C.;
Chen, Minjun;
Wright, Robert A.;
Tsaioun, Katya

Publication type:

Article

Non-cancer to anti-cancer: investigation of human ether-a-go-go-related gene potassium channel inhibitors as potential therapeutics.

Published in:

Journal of the Egyptian National Cancer Institute, 2021, v. 33, n. 1, p. 1, doi. 10.1186/s43046-021-00091-3

By:

Patil, Vaishali M.;
Gaurav, Anand;
Garg, Priyanka;
Masand, Neeraj

Publication type:

Article

Case studies: Weight gain in two troglitazone-treated patients with improved glycemic control.

Published in:

1999

By:

Ragone, Marguerite;
Lando, Howard M.

Publication type:

Case Study

Case study: Making the clinical diagnosis of type 2 diabetes based on family history.

Published in:

Clinical Diabetes, 1999, v. 17, n. 1, p. 31

By:

Peters, Anne

Publication type:

Article

The effect of Baicalin, a PPARy activator, on erythroid differentiation of CD133<sup>+</sup> cord blood hematopoietic stem cells.

Published in:

Scientific Journal of Iranian Blood Transfusion Organization, 2014, v. 11, n. 1, p. 12

By:

Abbasi, P.;
Asanjan, K. Shams;
Movasaghpour, A. A.;
Laleh, P. Akbarzadeh;
Dehdilani, N.

Publication type:

Article

Troglitazone and Δ2Troglitazone Enhance Adiponectin Expression in Monocytes/Macrophages through the AMP-Activated Protein Kinase Pathway.

Published in:

Mediators of Inflammation, 2014, v. 2014, p. 1, doi. 10.1155/2014/726068

By:

Jaw-Shiun Tsai;
Lee-Ming Chuang;
Ching-Shih Chen;
Chan-Jung Liang;
Yuh-Lien Chen;
Ching-Yu Chen

Publication type:

Article

Simvastatin inhibited oxLDL-induced proatherogenic effects through calpain-1-PPARγ-CD36 pathway.

Published in:

Canadian Journal of Physiology & Pharmacology, 2016, v. 94, n. 12, p. 1336, doi. 10.1139/cjpp-2016-0295

By:

Yang, Xueyan;
Yin, Meihui;
Yu, Lan;
Lu, Meili;
Wang, Hongxin;
Tang, Futian;
Zhang, Yingjie

Publication type:

Article

Differential Effect of Troglitazone on the Human Bile Acid Transporters, MRP2 and BSEP, in the PXB Hepatic Chimeric Mouse.

Published in:

Toxicologic Pathology, 2012, v. 40, n. 8, p. 1106, doi. 10.1177/0192623312447542

By:

Foster, John R.;
Jacobsen, Matt;
Kenna, Gerry;
Schulz-Utermoehl, Timothy;
Morikawa, Yoshio;
Salmu, Juuso;
Wilson, Ian D.

Publication type:

Article

Characterization of a novel murine preadipocyte line, AP-18, isolated from subcutaneous tissue: analysis of adipocyte-related gene expressions.

Published in:

Cell Biology International, 2010, v. 34, n. 3, p. 293, doi. 10.1042/CBI20090063

By:

Chen Chen;
Kazuma Takahashi;
Ayumi Yoshida;
Yumiko Takizawa;
Yan Lee;
Masaki Nakui;
Hideyuki Doi;
Yuji Takebayashi;
Manabu Fukumoto;
Testuya Yamada;
Hideki Katagiri;
Yoshitomo Oka;
Jo Satoh

Publication type:

Article

Troglitazone inhibits the migration and invasion of PC‑3 human prostate cancer cells by upregulating E‑cadherin and glutathione peroxidase 3.

Published in:

Oncology Letters, 2018, v. 16, n. 4, p. 5482, doi. 10.3892/ol.2018.9278

By:

Chang, Seo-Na;
Lee, Ji Min;
Oh, Hanseul;
Kim, Ukjin;
Ryu, Bokyeong;
Park, Jae-Hak

Publication type:

Article

New Treatments for Patients With Diabetes.

Published in:

Diabetes Spectrum, 1998, v. 11, n. 1, p. 18

By:

Rodeen, Lisa M.;
Baker, Danial E.;
Campbell, R. Keith

Publication type:

Article

The Pharmacologic Management of Patients with Type II Diabetes Mellitus in the Era of New Oral Agents and Insulin Analogs.

Published in:

Diabetes Spectrum, 1996, v. 9, n. 4, p. 227

By:

White Jr., John R.

Publication type:

Article

SPECTRUM BEAT.

Published in:

Diabetes Spectrum, 1995, v. 8, n. 3, p. 180

By:

Guffey, Laurie

Publication type:

Article

Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity.

Published in:

Clinical Pharmacology & Therapeutics, 2014, v. 96, n. 5, p. 589, doi. 10.1038/clpt.2014.158

By:

Yang, K;
Woodhead, J L;
Watkins, P B;
Howell, B A;
Brouwer, K L R

Publication type:

Article

Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon cancer.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61661-4

By:

Yoon, Joon-Kee;
Byeon, Hye Eun;
Ko, Seung Ah;
Park, Bok-Nam;
An, Young-Sil;
Lee, Ho-Young;
Lee, Youn Woo;
Lee, Su Jin

Publication type:

Article

In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2017, v. 36, p. 1, doi. 10.1186/s13046-017-0557-6

By:

Megumi Fujita;
Ai Hasegawa;
Motohiro Yamamori;
Noboru Okamura

Publication type:

Article

Dynamic culture of human liver equivalents inside a micro-bioreactor for long-term substance testing.

Published in:

BMC Proceedings, 2013, p. 1, doi. 10.1186/1753-6561-7-S6-P72

By:

Materne, Eva-Maria;
Wagner, Ilka;
Frädrich, Caroline;
Süβbier, Ute;
Horland, Reyk;
Hoffmann, Silke;
Brincker, Sven;
Lorenz, Alexandra;
Gruchow, Matthias;
Sonntag, Frank;
Klotzbach, Udo;
Lauster, Roland;
Marx, Uwe

Publication type:

Article

Assessment of troglitazone induced liver toxicity in a dynamically perfused two-organ Micro-Bioreactor system.

Published in:

BMC Proceedings, 2013, p. 1, doi. 10.1186/1753-6561-7-S6-P71

By:

Materne, Eva-Maria;
Frädrich, Caroline;
Horland, Reyk;
Hoffmann, Silke;
Brincker, Sven;
Lorenz, Alexandra;
Busek, Mathias;
Sonntag, Frank;
Klotzbach, Udo;
Lauster, Roland;
Marx, Uwe;
Wagner, Ilka

Publication type:

Article

Correction: Combined Treatment with Troglitazone and Lovastatin Inhibited Epidermal Growth Factor-Induced Migration through the Downregulation of Cysteine-Rich Protein 61 in Human Anaplastic Thyroid Cancer Cells.

Published in:

2017

By:

Chin, Li-Han;
Hsu, Sung-Po;
Zhong, Wen-Bin;
Liang, Yu-Chih

Publication type:

Correction Notice

The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitntriors.

Published in:

Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03319-z

By:

Muller, Claire;
Lacroix-Malgras, Victorine;
Kluza, Jérôme;
Laine, William;
Güler, Yonca;
Bost, Frédéric;
Boisbrun, Michel;
Mazerbourg, Sabine;
Flament, Stéphane

Publication type:

Article

RED TAPE TIGHTROPE: REGULATING FINANCIAL CONFLICTS OF INTEREST IN FDA ADVISORY COMMITTEES.

Published in:

Washington University Law Review, 2014, v. 91, n. 6, p. 1591

By:

Davis, Colleen O.

Publication type:

Article

XML-CIMT: Explainable Machine Learning (XML) Model for Predicting Chemical-Induced Mitochondrial Toxicity.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15655, doi. 10.3390/ijms232415655

By:

Jaganathan, Keerthana;
Rehman, Mobeen Ur;
Tayara, Hilal;
Chong, Kil To

Publication type:

Article

Troglitazone and tumor inhibition: an evolving concept in the management of systemic malignancies.

Published in:

2012

By:

Kapoor, Shailendra

Publication type:

Letter

Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1335836

By:

Quanfeng Deng;
Youlong Yang;
Yuangui Liu;
Mengting Zou;
Guiyuan Huang;
Shiqi Yang;
Lingyu Li;
Yueyang Qu;
Yong Luo;
Xiuli Zhang

Publication type:

Article

Mechanistic Insights into Side Effects of Troglitazone and Rosiglitazone Using a Novel Inverse Molecular Docking Protocol.

Published in:

Pharmaceutics, 2021, v. 13, n. 3, p. 315, doi. 10.3390/pharmaceutics13030315

By:

Kores, Katarina;
Konc, Janez;
Bren, Urban;
Dal Piaz, Fabrizio

Publication type:

Article

Antiproliferative effects and molecular mechanisms of troglitazone in human cervical cancer in vitro.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 1211, doi. 10.2147/OTT.S79899

By:

Jinjun Ye;
Li Yin;
Peng Xie;
Jianfeng Wu;
Jian Huang;
Guoren Zhou;
Hanzi Xu;
Emei Lu;
Xia He

Publication type:

Article

Combined Treatment with Troglitazone and Lovastatin Inhibited Epidermal Growth Factor-Induced Migration through the Downregulation of Cysteine-Rich Protein 61 in Human Anaplastic Thyroid Cancer Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118674

By:

Chin, Li-Han;
Hsu, Sung-Po;
Zhong, Wen-Bin;
Liang, Yu-Chih

Publication type:

Article

9-<i>cis</i>-Retinoic Acid and Troglitazone Impacts Cellular Adhesion, Proliferation, and Integrin Expression in K562 Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0093005

By:

Hanson, Amanda M.;
Gambill, Jessica;
Phomakay, Venusa;
Staten, C. Tyler;
Kelley, Melissa D.

Publication type:

Article

Troglitazone Attenuates TGF-β1-Induced EMT in Alveolar Epithelial Cells via a PPARγ-Independent Mechanism.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038827

By:

Zhou, Beiyun;
Buckley, Stephen T.;
Patel, Vipul;
Liu, Yixin;
Luo, Jiao;
Sai Krishnaveni, Manda;
Ivan, Mihaela;
DeMaio, Lucas;
Kim, Kwang-Jin;
Ehrhardt, Carsten;
Crandall, Edward D.;
Borok, Zea

Publication type:

Article

3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies.

Published in:

Toxicological Sciences, 2013, v. 133, n. 1, p. 67, doi. 10.1093/toxsci/kft021

By:

Gunness, Patrina;
Mueller, Daniel;
Shevchenko, Valery;
Heinzle, Elmar;
Ingelman-Sundberg, Magnus;
Noor, Fozia

Publication type:

Article

Use and Abuse of "Historical Experts" in Toxic Tort Cases.

Published in:

Defense Counsel Journal, 2015, v. 82, n. 3, p. 321

By:

Kozak, Scott

Publication type:

Article

An Impaired Immune Tolerance Animal Model Distinguishes the Potential of Troglitazone/Pioglitazone and Tolcapone/Entacapone to Cause IDILI.

Published in:

Toxicological Sciences, 2018, v. 161, n. 2, p. 412, doi. 10.1093/toxsci/kfx219

By:

Mak, Alastair;
Kato, Ryuji;
Weston, Kyle;
Hayes, Anthony;
Uetrecht, Jack

Publication type:

Article

Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.

Published in:

Toxicological Sciences, 2018, v. 161, n. 1, p. 58, doi. 10.1093/toxsci/kfx195

By:

Cook, Jon C;
Obert, Leslie A;
Koza-Taylor, Petra;
Coskran, Timothy M;
Opsahl, Alan C;
Ziemek, Daniel;
Roy, Marc;
Qian, Jessie;
Lawton, Michael P;
Criswell, Kay A

Publication type:

Article

Troglitazone Inhibits Bile Acid Amidation: A Possible Risk Factor for Liver Injury.

Published in:

Toxicological Sciences, 2017, v. 158, n. 2, p. 347, doi. 10.1093/toxsci/kfx091

By:

Eiichiro Ogimura;
Tetsuya Nakagawa;
Jiro Deguchi;
Shuichi Sekine;
Kousei Ito;
Kiyoko Bando

Publication type:

Article

Rosiglitazone attenuates the severity of hyperlipidemic severe acute pancreatitis in rats.

Published in:

Experimental & Therapeutic Medicine, 2013, v. 6, n. 4, p. 989, doi. 10.3892/etm.2013.1255

By:

BATUR NIYAZ;
KAI-LIANG ZHAO;
LI-MIN LIU;
CHEN CHEN;
WEN-HONG DENG;
TENG ZUO;
QIAO SHI;
WEI-XING WANG

Publication type:

Article

Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 1, p. 167, doi. 10.3109/10428194.2012.708026

By:

Jardine, Laura;
Hambleton, Sophie;
Bigley, Venetia;
Pagan, Sarah;
Wang, Xiao-Nong;
Collin, Matthew

Publication type:

Article

Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice.

Published in:

Xenobiotica, 2014, v. 44, n. 2, p. 186, doi. 10.3109/00498254.2013.879237

By:

Samuelsson, Kristin;
Pickup, Kathryn;
Sarda, Sunil;
Foster, John R.;
Randall, Kevin;
Abrahamsson, Anna;
Jacobsen, Matt;
Weidolf, Lars;
Wilson, Ian

Publication type:

Article

Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone.

Published in:

Xenobiotica, 2014, v. 44, n. 2, p. 174, doi. 10.3109/00498254.2013.867463

By:

Barnes, Alan J.;
Baker, David R.;
Hobby, Kirsten;
Ashton, Simon;
Michopoulos, Filippos;
Spagou, Konstantina;
Loftus, Neil J.;
Wilson, Ian D.

Publication type:

Article

Evaluation of the pharmacokinetics, biotransformation and hepatic transporter effects of troglitazone in mice with humanized livers.

Published in:

Xenobiotica, 2012, v. 42, n. 6, p. 503, doi. 10.3109/00498254.2011.640716

By:

Schulz-Utermoehl, Timothy;
Sarda, Sunil;
Foster, John R.;
Jacobsen, Matt;
Kenna, J. Gerry;
Morikawa, Yoshio;
Salmu, Juuso;
Gross, Gerhard;
Wilson, Ian D.

Publication type:

Article

Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy.

Published in:

Yonsei Medical Journal, 2016, v. 57, n. 6, p. 1494, doi. 10.3349/ymj.2016.57.6.1494

By:

Hyunju Park;
Si-Hwan Ko;
Jae Myun Lee;
Jeon Han Park;
Youn-Hee Choi

Publication type:

Article

Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.

Published in:

Journal of Inflammation, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12950-014-0044-1

By:

Marcone, Simone;
Haughton, Karen;
Simpson, Paul;
Belton, Orina;
Fitzgerald, Desmond J.

Publication type:

Article