Works matching DE "TRIPTOLIDE"

Results: 317

Triptolide augments the effects of 5-lipoxygenase RNA interference in suppressing pancreatic tumor growth in a xenograft mouse model.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 1, p. 253, doi. 10.1007/s00280-011-1698-5

By:

Ding, Xiaoling;
Zhou, Xiaorong;
Zhang, Haifeng;
Qing, Jingdan;
Qiang, Hui;
Zhou, Guoxiong

Publication type:

Article

Triptolide ameliorates osteoarthritis by regulating nuclear factor kappa B-mediated inflammatory response.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 3, p. 360, doi. 10.1093/jpp/rgab182

By:

Liu, Gang;
Wang, Laijie;
Tuerxunyiming, Muhadasi;
Xu, Jin;
Wu, Zaifeng;
Wang, Wei;
Liu, Hongyu;
Lin, Lin;
Liu, Qingbai

Publication type:

Article

Molecular pathogenesis, mechanism and therapy of Cav1 in prostate cancer.

Published in:

Discover Oncology, 2023, v. 14, n. 1, p. 1, doi. 10.1007/s12672-023-00813-0

By:

Bian, Qiang;
Li, Bei;
Zhang, Luting;
Sun, Yinuo;
Zhao, Zhankui;
Ding, Yi;
Yu, Honglian

Publication type:

Article

Triptolide attenuates LPS-induced activation of RAW 264.7 macrophages by inducing M1-to-M2 repolarization via the mTOR/STAT3 signaling.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 6, p. 894, doi. 10.1080/08923973.2022.2093738

By:

Zhu, Huanhuan;
Tong, Shaopeng;
Yan, Congrong;
Zhou, Acheng;
Wang, Minying;
Li, Chunwei

Publication type:

Article

Triptolide inhibits Th17 differentiation via controlling PKM2-mediated glycolysis in rheumatoid arthritis.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 6, p. 838, doi. 10.1080/08923973.2022.2086139

By:

Shen, Mei-Yu;
Wang, Xiang;
Di, Yu-Xi;
Zhang, Ming-Fei;
Tian, Feng-Xiang;
Qian, Fei-Ya;
Jiang, Bao-Ping;
Zhou, Ling-Ling

Publication type:

Article

Anti-inflammatory effects of triptolide on IgA nephropathy in rats.

Published in:

Immunopharmacology & Immunotoxicology, 2015, v. 37, n. 5, p. 421, doi. 10.3109/08923973.2015.1080265

By:

He, Liyu;
Peng, Xiaofei;
Liu, Guoyong;
Tang, Chengyuan;
Liu, Hong;
Liu, Fuyou;
Zhou, He;
Peng, Youming

Publication type:

Article

MYC2 Transcription Factors TwMYC2a and TwMYC2b Negatively Regulate Triptolide Biosynthesis in Tripterygium wilfordii Hairy Roots.

Published in:

Plants (2223-7747), 2021, v. 10, n. 4, p. 679, doi. 10.3390/plants10040679

By:

Huo, Yanbo;
Zhang, Jing;
Zhang, Bin;
Chen, Ling;
Zhang, Xing;
Zhu, Chuanshu

Publication type:

Article

LED Lights Affecting Morphogenesis and Isosteroidal Alkaloid Contents in Fritillaria cirrhosa D. Don—An Important Chinese Medicinal Herb.

Published in:

Plants (2223-7747), 2020, v. 9, n. 10, p. 1351, doi. 10.3390/plants9101351

By:

Chen, Chia-Chen;
Lee, Maw-Rong;
Wu, Chi-Rei;
Ke, Hsin-Ju;
Xie, Hui-Min;
Tsay, Hsin-Sheng;
Agrawal, Dinesh Chandra;
Chang, Hung-Chi

Publication type:

Article

A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.85862

By:

Qiaomu Tian;
Peng Zhang;
Yihan Wang;
Youhui Si;
Dengping Yin;
Weber, Christopher R.;
Fishel, Melissa L.;
Pollok, Karen E.;
Bo Qiu;
Fei Xiao;
Chong, Anita S.

Publication type:

Article

Quantitative proteomic analysis of circulating exosomes reveals the mechanism by which Triptolide protects against collagen‐induced arthritis.

Published in:

Immunity, Inflammation & Disease, 2024, v. 12, n. 6, p. 1, doi. 10.1002/iid3.1322

By:

Liu, Xiuchan;
Liu, Xu;
Wang, Hui;
Chen, Ming;
Zhang, Geng;
Ren, Dongyun;
Zhang, Na;
Wei, Wei

Publication type:

Article

Antiviral activity of triptolide on herpes simplex virus in vitro.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 7, p. 1, doi. 10.1002/iid3.667

By:

Aliabadi, Nasrin;
Jamalidoust, Marzieh;
Pouladfar, Gholamreza;
Ziyaeyan, Atoosa;
Ziyaeyan, Mazyar

Publication type:

Article

Network pharmacology and experiment validation investigate the potential mechanism of triptolide in oral squamous cell carcinoma.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1302059

By:

Puyu Hao;
Pengcheng Zhang;
Ying Liu;
Yang Cao;
Lianqun Du;
Li Gao;
Qingyang Dong

Publication type:

Article

Triptolide enhances carboplatin-induced apoptosis by inhibiting nucleotide excision repair (NER) activity in melanoma.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1157433

By:

Geng Wang;
Hongmin Guo;
Yan Ren;
Weiyi Chen;
Yixuan Wang;
Jianing Li;
Hua Liu;
Jingjun Xing;
Yanru Zhang;
Na Li

Publication type:

Article

Effect of the Natural Product Triptolide on Pancreatic Cancer: A Systematic Review of Preclinical Studies.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00490

By:

Chi Zhang;
Xiao-Juan He;
Li Li;
Cheng Lu;
Ai-Ping Lu

Publication type:

Article

Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00260

By:

Jing Yang;
Lixin Sun;
Lu Wang;
Hassan, Hozeifa M.;
Xuan Wang;
Hylemon, Phillip B.;
Tao Wang;
Huiping Zhou;
Luyong Zhang;
Zhenzhou Jiang

Publication type:

Article

Triptolide Upregulates Myocardial Forkhead Helix Transcription Factor p3 Expression and Attenuates Cardiac Hypertrophy.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00471

By:

Yuan-Yuan Ding;
Jing-Mei Li;
Feng-Jie Guo;
Ya Liu;
Yang-Fei Tong;
Xi-Chun Pan;
Xiao-Lan Lu;
Wen Ye;
Xiao-Hong Chen;
Hai-Gang Zhang

Publication type:

Article

Control Effect of Triptolide on Farmland Rats in Sanya City.

Published in:

Plant Diseases & Pests, 2017, v. 8, n. 1, p. 30

By:

Wang Shuo;
Yuan Weifang;
Chen Chuanfeng;
Li Zuli;
Deng Dezhi;
Luo Hongwei

Publication type:

Article

Preventive and management approach of triptonide, a diterpenoid compound against streptozotocin-induced diabetic retinopathy in Wistar rat model.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 9, p. N.PAG, doi. 10.1016/j.arabjc.2023.105034

By:

Govindasamy, Chandramohan;
Al-Numair, Khalid S.;
Li, Jun;
Chen, Weibai;
Wu, Guoqiang

Publication type:

Article

Development and optimization of sustained release triptolide microspheres.

Published in:

PLoS ONE, 2023, v. 18, n. 10, p. 1, doi. 10.1371/journal.pone.0292861

By:

Zeng, Hui-lin;
Qiu, Qian;
Fu, Ting-xiong;
Deng, Ai-ping;
Xie, Xiang-yang

Publication type:

Article

Triptolide Improves Cognitive Dysfunction in Rats with Vascular Dementia by Activating the SIRT1/PGC-1α Signaling Pathway.

Published in:

Neurochemical Research, 2019, v. 44, n. 8, p. 1977, doi. 10.1007/s11064-019-02831-3

By:

Yao, Peng;
Li, Yiling;
Yang, Yujun;
Yu, Shuchun;
Chen, Yong

Publication type:

Article

Targeting of Heat Shock Protein HSPA6 (HSP70B′) to the Periphery of Nuclear Speckles is Disrupted by a Transcription Inhibitor Following Thermal Stress in Human Neuronal Cells.

Published in:

Neurochemical Research, 2017, v. 42, n. 2, p. 406, doi. 10.1007/s11064-016-2084-9

By:

Becirovic, Larissa;
Brown, Ian

Publication type:

Article

Combinational Pretreatment of Colony-Stimulating Factor 1 Receptor Inhibitor and Triptolide Upregulates BDNF-Akt and Autophagic Pathways to Improve Cerebral Ischemia.

Published in:

Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/8796103

By:

Du, Xiaoxue;
Gao, Feng;
Chen, Shijia;
Botchway, Benson O. A.;
Amin, Nashwa;
Hu, Zhiying;
Fang, Marong

Publication type:

Article

Synthesis and structure--activity relationship of kujigamberol B, a dinorlabdane diterpenoid isolated from an ancient Kuji amber.

Published in:

Bioscience, Biotechnology & Biochemistry, 2023, v. 87, n. 6, p. 575, doi. 10.1093/bbb/zbad027

By:

Sakura Kishibata;
Kurumi Tanaka;
Tatsuo Saito;
Ken-ichi Kimura;
Arata Yajima

Publication type:

Article

Triptolide inhibits proliferation and invasion of malignant glioma cells.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 53, doi. 10.1007/s11060-012-0885-5

By:

Zhang, Haipeng;
Zhu, Wenbo;
Su, Xingwen;
Wu, Sihan;
Lin, Yuan;
Li, Jingjie;
Wang, Youqiong;
Chen, Jingkao;
Zhou, Yuxi;
Qiu, Pengxin;
Yan, Guangmei;
Zhao, Shujin;
Hu, Jun;
Zhang, Jingxia

Publication type:

Article

Neuroprotective mechanisms of mangiferin in neurodegenerative diseases.

Published in:

Drug Development Research, 2021, v. 82, n. 4, p. 494, doi. 10.1002/ddr.21783

By:

Liu, Tingjun;
Song, Yuanjian;
Hu, Ankang

Publication type:

Article

Antiestrogenic Activity of Triptolide in Human Breast Cancer Cells MCF-7 and Immature Female Mouse.

Published in:

Drug Development Research, 2017, v. 78, n. 3/4, p. 164, doi. 10.1002/ddr.21387

By:

Tang, Yi;
Wang, Jun;
Cheng, Jinghua;
Wang, Lijun

Publication type:

Article

Pharmacokinetic Study of Triptolide Nanocarrier in Transdermal Drug Delivery System—Combination of Experiment and Mathematical Modeling.

Published in:

Molecules, 2023, v. 28, n. 2, p. 553, doi. 10.3390/molecules28020553

By:

Yang, Meng;
Meng, Jianxia;
Han, Lu;
Yu, Xiaoyan;
Fan, Zhimin;
Yuan, Yongfang

Publication type:

Article

TP-CSO: A Triptolide Prodrug for Pancreatic Cancer Treatment.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3686, doi. 10.3390/molecules27123686

By:

Wang, Xinlong;
Zeng, Huahui;
Zhu, Xin;
Xu, Duanjie;
Tian, Qikang;
Wang, Can;
Zhao, Lingzhou;
Zhao, Junwei;
Miao, Mingsan;
Wu, Xiangxiang

Publication type:

Article

Transforming of Triptolide into Characteristic Metabolites by the Gut Microbiota.

Published in:

Molecules, 2020, v. 25, n. 3, p. 606, doi. 10.3390/molecules25030606

By:

Peng, Ran;
Ma, Shu-Rong;
Fu, Jie;
Han, Pei;
Pan, Li-Bin;
Zhang, Zheng-Wei;
Yu, Hang;
Wang, Yan

Publication type:

Article

Protic Ionic Liquids as Efficient Solvents in Microwave-Assisted Extraction of Rhein and Emodin from Rheum palmatum L.

Published in:

Molecules, 2019, v. 24, n. 15, p. 2770, doi. 10.3390/molecules24152770

By:

Fan, Yunchang;
Niu, Zeyu;
Xu, Chen;
Yang, Lei;
Yang, Tuojie;
Nardi, Monica;
Procopio, Antonio;
Di Gioia, Maria Luisa

Publication type:

Article

CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii.

Published in:

Molecules, 2019, v. 24, n. 11, p. 2162, doi. 10.3390/molecules24112162

By:

Jin, Chunhuan;
Wu, Zijun;
Wang, Lili;
Kanai, Yoshikatsu;
He, Xin

Publication type:

Article

Production of Putative Diterpene Carboxylic Acid Intermediates of Triptolide in Yeast.

Published in:

Molecules, 2017, v. 22, n. 6, p. 981, doi. 10.3390/molecules22060981

By:

Forman, Victor;
Callari, Roberta;
Folly, Christophe;
Heider, Harald;
Hamberger, Björn

Publication type:

Article

Absorption and Metabolism Characteristics of Triptolide as Determined by a Sensitive and Reliable LC-MS/MS Method.

Published in:

Molecules, 2015, v. 20, n. 5, p. 8928, doi. 10.3390/molecules20058928

By:

Xiaomei Gong;
Yan Chen;
Yi Wu

Publication type:

Article

Triptolide Induces S Phase Arrest and Apoptosis in Gallbladder Cancer Cells.

Published in:

Molecules, 2014, v. 19, n. 2, p. 2612, doi. 10.3390/molecules19022612

By:

Yun-Ping Hu;
Zhu-Jun Tan;
Xiang-Song Wu;
Tian-Yu Liu;
Lin Jiang;
Run-Fa Bao;
Yi-Jun Shu;
Mao-Lan Li;
Hao Weng;
Qian Ding;
Feng Tao;
Ying-Bin Liu

Publication type:

Article

Preparation and Optimization of Triptolide-Loaded Solid Lipid Nanoparticles for Oral Delivery with Reduced Gastric Irritation.

Published in:

Molecules, 2013, v. 18, n. 11, p. 13340, doi. 10.3390/molecules181113340

By:

Cong Zhang;
Conghui Gu;
Fan Peng;
Wei Liu;
Jiangling Wan;
Huibi Xu;
Lam, Christopher Waikei;
Xiangliang Yang

Publication type:

Article

Triptolide Improves Early Survival of Mesenchymal Stem Cells Transplanted into Rat Myocardium.

Published in:

Cardiology, 2014, v. 128, n. 2, p. 73, doi. 10.1159/000356551

By:

Zhang, Changhai;
Nong, Yaoming;
Tong, Shifei;
Yao, Qing;
Wen, Lei;
Zhang, Zhihui;
Wei, Lu;
Cheng, Jun;
Feng, Yuanyuan;
Song, Zhiyuan

Publication type:

Article

Preparation and anti-inflammatory activity of triptolide ethosomes in an erythema model.

Published in:

Journal of Liposome Research, 2010, v. 20, n. 4, p. 297, doi. 10.3109/08982100903544144

By:

Chen, Jin-Guang;
Liu, Yu-Feng;
Gao, Tian-Wen

Publication type:

Article

Transferrin-Modified Triptolide Liposome Targeting Enhances Anti-Hepatocellular Carcinoma Effects.

Published in:

Biomedicines, 2023, v. 11, n. 10, p. 2869, doi. 10.3390/biomedicines11102869

By:

Zhao, Xiaoli;
Yang, Yifan;
Su, Xuerong;
Xie, Ying;
Liang, Yiyao;
Zhou, Tong;
Wu, Yangqian;
Di, Liuqing

Publication type:

Article

Celastrol and Triptolide Suppress Stemness in Triple Negative Breast Cancer: Notch as a Therapeutic Target for Stem Cells.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 482, doi. 10.3390/biomedicines9050482

By:

Ramamoorthy, Prabhu;
Dandawate, Prasad;
Jensen, Roy A.;
Anant, Shrikant;
Natarajan, Sathish Kumar

Publication type:

Article

Characteristics of Sedimentary Organic Matter and Phosphorus in Minor Rivers Discharging into Zhejiang Coast, China.

Published in:

Geosciences (2076-3263), 2020, v. 10, n. 9, p. 357, doi. 10.3390/geosciences10090357

By:

Loh, Pei Sun;
Cheng, Long-Xiu;
Lin, Shi-Yuan;
Kandasamy, Selvaraj

Publication type:

Article

Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1077640

By:

Chao Yuan;
Yanli Liao;
Shengjie Liao;
Mi Huang;
Duanzhuo Li;
Weibin Wu;
Yi Quan;
Liqiang Li;
Xin Yu;
Wenxia Si

Publication type:

Article

A Supramolecular Nanovehicle Featuring a pH/Enzyme Co‐Response for Targeted Delivery of the Antitumor Compound.

Published in:

ChemPlusChem, 2023, v. 88, n. 5, p. 1, doi. 10.1002/cplu.202300069

By:

Nie, Zhengquan;
Zhu, Fangdao;
Chen, Shuai;
Xu, Junxin;
Yang, Jianmei;
He, Junnan;
Liu, Xiaoqing;
Zhao, Yan;
Zhang, Jin

Publication type:

Article

Camptothecin, triptolide, and apoptosis inducer kit have differential effects on mitochondria in colorectal carcinoma cells.

Published in:

FEBS Open Bio, 2022, v. 12, n. 5, p. 913, doi. 10.1002/2211-5463.13401

By:

Liskova, Veronika;
Kajsik, Marek;
Chovancova, Barbora;
Roller, Ladislav;
Krizanova, Olga

Publication type:

Article

Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.

Published in:

Human & Experimental Toxicology, 2021, v. 40, p. S775, doi. 10.1177/09603271211056330

By:

Jiang, Hai-Yan;
Bao, Yan-Ni;
Lin, Feng-Mei;
Jin, Yong

Publication type:

Article

Exposure to triptolide affects follicle development in NIH mice.

Published in:

Human & Experimental Toxicology, 2017, v. 36, n. 1, p. 82, doi. 10.1177/0960327116638725

By:

Zeng, Y.;
Sun, H.;
Li, Y.;
Shao, M.;
Han, P.;
Yu, X.;
He, L.;
Xu, Y.;
Li, S.

Publication type:

Article

EFFECT OF ADDITIVES ON STRUCTURE AND PROPERTIES OF ELECTRODEPOSITED NANOCRYSTALLINE COPPER.

Published in:

Rasayan Journal of Chemistry, 2020, v. 13, n. 4, p. 2143, doi. 10.31788/RJC.2020.1345893

By:

Ramalingam, S.

Publication type:

Article

Triptolide-Conditioned Dendritic Cells Induce Allospecific T-Cell Regulation and Prolong Renal Graft Survival.

Published in:

Journal of Investigative Surgery, 2013, v. 26, n. 4, p. 191, doi. 10.3109/08941939.2012.737408

By:

Zhang, Gutian;
Chen, Junhao;
Liu, Yong;
Yang, Rong;
Guo, Hongqian;
Sun, Zeyu

Publication type:

Article

Differential immunomodulatory effects by Tripterygium wilfordii Hook f-derived refined extract PG27 and its purified component PG490 (triptolide) in human peripheral blood T cells: potential therapeutics for arthritis and possible mechanismfs explaining in part Chinese herbal theory "Junn-Chenn-Zuou-SS"

Published in:

Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-294

By:

Ling-Jun Ho;
Wen-Liang Chang;
Ann Chen;
Ping Chao;
Jenn-Haung Lai

Publication type:

Article

Genome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1614-1

By:

Chauhan, Lata;
Jenkins, Gregory D.;
Bhise, Neha;
Feldberg, Tanya;
Mitra-Ghosh, Taraswi;
Fridley, Brooke L.;
Lamba, Jatinder K.

Publication type:

Article

Triptolide improves systolic function and myocardial energy metabolism of diabetic cardiomyopathy in streptozotocin-induced diabetic rats.

Published in:

BMC Cardiovascular Disorders, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12872-015-0030-4

By:

Zhongshu Liang;
Sunnar Leo;
Helin Wen;
Mao Ouyang;
Weihong Jiang;
Kan Yang

Publication type:

Article