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Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13522-6
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- Publication type:
- Article
First Oral Sleeping Sickness Drug.
- Published in:
- 2019
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- Publication type:
- journal article
Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs.
- Published in:
- Molecules, 2019, v. 24, n. 2, p. 268, doi. 10.3390/molecules24020268
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- Publication type:
- Article
<italic>Trypanosoma brucei rhodesiense</italic> infection in a Chinese traveler returning from the Serengeti National Park in Tanzania.
- Published in:
- 2018
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- Publication type:
- Case Study
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.
- Published in:
- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 5, p. 1, doi. 10.1371/journal.pntd.0006450
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- Publication type:
- Article
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
- Published in:
- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 2, p. 1, doi. 10.1371/journal.pntd.0006301
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- Publication type:
- Article
African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System.
- Published in:
- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00218
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- Publication type:
- Article
Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.
- Published in:
- PLoS Pathogens, 2018, v. 14, n. 2, p. 1, doi. 10.1371/journal.ppat.1006850
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- Publication type:
- Article
Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.
- Published in:
- Molecules, 2018, v. 23, n. 1, p. 177, doi. 10.3390/molecules23010177
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- Publication type:
- Article
Expression of interferon-inducible chemokines and sleep/wake changes during early encephalitis in experimental African trypanosomiasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 8, p. 1, doi. 10.1371/journal.pntd.0005854
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- Publication type:
- Article
Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 6, p. 1, doi. 10.1371/journal.pntd.0005438
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- Publication type:
- Article
Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: Implications for vector control.
- Published in:
- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 4, p. 1, doi. 10.1371/journal.pntd.0005485
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- Publication type:
- Article
Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB).
- Published in:
- PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173474
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- Publication type:
- Article
Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 3, p. 1, doi. 10.1371/journal.pntd.0005432
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- Publication type:
- Article
Predicting the Impact of Intervention Strategies for Sleeping Sickness in Two High-Endemicity Health Zones of the Democratic Republic of Congo.
- Published in:
- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 1, p. 1, doi. 10.1371/journal.pntd.0005162
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- Publication type:
- Article
Trypanosoma brucei Invasion and T-cell Infiltration of the Brain Parenchyma in Experimental Sleeping Sickness: Timing and Correlation with Functional Changes.
- Published in:
- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 12, p. 1, doi. 10.1371/journal.pntd.0005242
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- Publication type:
- Article
Determinants of Human African Trypanosomiasis Elimination via Paratransgenesis.
- Published in:
- PLoS Neglected Tropical Diseases, 2016, v. 10, n. 3, p. 1, doi. 10.1371/journal.pntd.0004465
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- Publication type:
- Article
Discovery of Infection Associated Metabolic Markers in Human African Trypanosomiasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 10, p. 1, doi. 10.1371/journal.pntd.0004200
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- Publication type:
- Article
Quantitative evaluation of the strategy to eliminate human African trypanosomiasis in the Democratic Republic of Congo.
- Published in:
- Parasites & Vectors, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13071-015-1131-8
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- Publication type:
- Article
Evaluation of Methanol Root Extract of Securidaca longipedunculata for Antitrypanosomal Activity in vitro and in vivo.
- Published in:
- Thai Journal of Pharmaceutical Sciences, 2015, v. 39, n. 4, p. 156
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- Publication type:
- Article
Updated estimate of the duration of the meningo-encephalitic stage in gambiense human African trypanosomiasis.
- Published in:
- BMC Research Notes, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13104-015-1244-3
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- Publication type:
- Article
On the Road to Elimination of Rhodesiense Human African Trypanosomiasis: First WHO Meeting of Stakeholders.
- Published in:
- 2015
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- Publication type:
- Proceeding
From Health Advice to Taboo: Community Perspectives on the Treatment of Sleeping Sickness in the Democratic Republic of Congo, a Qualitative Study.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 4, p. 1, doi. 10.1371/journal.pntd.0003686
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- Publication type:
- Article
Ziba Politics and the German Sleeping Sickness Camp at Kigarama, Tanzania, 1907-14.
- Published in:
- International Journal of African Historical Studies, 2014, v. 47, n. 3, p. 399
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- Publication type:
- Article
Determination of an Optimal Dosing Regimen for Fexinidazole, a Novel Oral Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Studies.
- Published in:
- Clinical Pharmacokinetics, 2014, v. 53, n. 6, p. 565, doi. 10.1007/s40262-014-0136-3
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- Publication type:
- Article
Structures of <i>Trypanosoma brucei</i> Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 4, p. 1, doi. 10.1371/journal.pntd.0002775
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- Publication type:
- Article
The Legacies of Eugène Jamot and <i>La Jamotique</i>.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 4, p. 1, doi. 10.1371/journal.pntd.0002635
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- Publication type:
- Article
Trypanocidal and cytotoxic evaluation of synthesized thiosemicarbazones as potential drug leads against sleeping sickness.
- Published in:
- Molecular Biology Reports, 2014, v. 41, n. 3, p. 1617, doi. 10.1007/s11033-013-3008-2
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- Publication type:
- Article
In Vitro Effect of Aqueous Extract and Fraction IV Portion of Ximenia americana Stem Bark on Trypanosoma congolense DNA.
- Published in:
- Journal of Parasitology Research, 2014, p. 1, doi. 10.1155/2014/904318
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- Publication type:
- Article
Diagnostic Accuracy of Loopamp <i>Trypanosoma brucei</i> Detection Kit for Diagnosis of Human African Trypanosomiasis in Clinical Samples.
- Published in:
- PLoS Neglected Tropical Diseases, 2013, v. 7, n. 10, p. 1, doi. 10.1371/journal.pntd.0002504
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- Publication type:
- Article
Exploring the <i>Trypanosoma brucei</i> Hsp83 Potential as a Target for Structure Guided Drug Design.
- Published in:
- PLoS Neglected Tropical Diseases, 2013, v. 7, n. 10, p. 1, doi. 10.1371/journal.pntd.0002492
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- Publication type:
- Article
Nifurtimox-Eflornithine Combination Therapy for Second-Stage Gambiense Human African Trypanosomiasis: Médecins Sans Frontières Experience in the Democratic Republic of the Congo.
- Published in:
- Clinical Infectious Diseases, 2013, v. 56, n. 2, p. 195, doi. 10.1093/cid/cis886
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- Publication type:
- Article
Drugs and drug resistance.
- Published in:
- WHO Technical Report Series, 2012, n. 975, p. 43
- Publication type:
- Article
Vaccines against Chagas disease, human African trypanosomiasis and leishmaniasis.
- Published in:
- WHO Technical Report Series, 2012, n. 975, p. 55
- Publication type:
- Article
Hit-to-Lead Development of the Chamigrane Endoperoxide Merulin A for the Treatment of African Sleeping Sickness.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046172
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- Publication type:
- Article
Safety and Efficacy of the 10-Day Melarsoprol Schedule for the Treatment of Second Stage Rhodesiense Sleeping Sickness.
- Published in:
- PLoS Neglected Tropical Diseases, 2012, v. 6, n. 8, p. 1, doi. 10.1371/journal.pntd.0001695
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- Publication type:
- Article
Early Prediction of Treatment Efficacy in Second-Stage Gambiense Human African Trypanosomiasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2012, v. 6, n. 6, p. 1, doi. 10.1371/journal.pntd.0001662
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- Publication type:
- Article
Molecular mechanisms and therapeutic approaches to the treatment of African Trypanosomiasis.
- Published in:
- Drug Invention Today, 2012, v. 4, n. 5, p. 381
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- Publication type:
- Article
Promising Leishmaniasis Drug.
- Published in:
- JAMA: Journal of the American Medical Association, 2012, v. 307, n. 11, p. 1129, doi. 10.1001/jama.2012.295
- Publication type:
- Article
Parasite infection: Understanding drug mechanisms of action.
- Published in:
- Nature Reviews Drug Discovery, 2012, v. 11, n. 3, p. 190, doi. 10.1038/nrd3692
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- Publication type:
- Article
Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis.
- Published in:
- Journal of Tropical Medicine (16879686), 2012, p. 1, doi. 10.1155/2012/340538
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- Publication type:
- Article
Monitoring the use of nifurtimox-eflornithine combination therapy (NECT) in the treatment of second stage gambiense human African trypanosomiasis.
- Published in:
- Research & Reports in Tropical Medicine, 2012, v. 3, p. 93, doi. 10.2147/rrtm.s34399
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- Publication type:
- Article
End in sight for sleeping sickness.
- Published in:
- Chemistry & Industry, 2011, n. 13, p. 6
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- Publication type:
- Article
Heat shock and awe.
- Published in:
- Nature Medicine, 2011, v. 17, n. 6, p. 646, doi. 10.1038/nm0611-646
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- Publication type:
- Article
Factory Tsetse Flies Must Behave Like Wild Flies: A Prerequisite for the Sterile Insect Technique.
- Published in:
- 2011
- By:
- Publication type:
- Opinion
Fexinidazole - A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 12, p. 1, doi. 10.1371/journal.pntd.0000923
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- Publication type:
- Article
Bayesian Geostatistical Analysis and Prediction of Rhodesian Human African Trypanosomiasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 12, p. 1, doi. 10.1371/journal.pntd.0000914
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- Publication type:
- Article
Novel Naphthalene-Based Inhibitors of Trypanosoma brucei RNA Editing Ligase 1.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 8, p. 1, doi. 10.1371/journal.pntd.0000803
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- Publication type:
- Article
In brief.
- Published in:
- 2010
- Publication type:
- Abstract
Controlling Sleeping Sickness--"When Will They Ever Learn?".
- Published in:
- 2010
- By:
- Publication type:
- Opinion