Works matching DE "TRANSCRIPTION factor Sp1"

Results: 197

Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators.

Published in:

Epigenetics & Chromatin, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13072-025-00598-2

By:

Bryan, Audra F.;
Justice, Megan;
Stutzman, Alexis V.;
McKay, Daniel J.;
Dowen, Jill M.

Publication type:

Article

Mutation and methylation status of KIT and TP<sub>53</sub> in canine cutaneous and subcutaneous mast cell tumours.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 3, p. 438, doi. 10.1111/vco.12543

By:

Vozdova, Miluse;
Kubickova, Svatava;
Fictum, Petr;
Cernohorska, Halina;
Fröhlich, Jan;
Rubes, Jiri

Publication type:

Article

Mechanistic insights into Uc001kfo-induced hepatocellular carcinoma metastasis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02000-9

By:

Pan, Yanfeng;
Liu, Qin;
Li, Qingqing;
Ren, Zhenjun

Publication type:

Article

Activation of TRAF1 induced by USP7/SP1 exacerbates the severity of infantile pneumonia.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00410-x

By:

Liu, Ying;
Ji, Yilun;
Zhang, Yu;
Li, Zhengsi

Publication type:

Article

ZO-2 favors Hippo signaling, and its re-expression in the steatotic liver by AMPK restores junctional sealing.

Published in:

Tissue Barriers, 2022, v. 10, n. 2, p. 1, doi. 10.1080/21688370.2021.1994351

By:

González-González, Laura;
Gallego-Gutiérrez, Helios;
Martin-Tapia, Dolores;
Avelino-Cruz, José Everardo;
Hernández-Guzmán, Christian;
Rangel-Guerrero, Sergio Israel;
Alvarez-Salas, Luis Marat;
Garay, Erika;
Chávez-Munguía, Bibiana;
Gutiérrez-Ruiz, María Concepción;
Hernández-Melchor, Dinorah;
López-Bayghen, Esther;
González-Mariscal, Lorenza

Publication type:

Article

En1 sweat we trust: How the evolution of an Engrailed 1 enhancer made humans the sweatiest ape.

Published in:

Temperature, 2022, v. 9, n. 4, p. 303, doi. 10.1080/23328940.2021.2019548

By:

Aldea, Daniel;
Kamberov, Yana G.

Publication type:

Article

LPS Increases 5-LO Expression on Monocytes via an Activation of Akt-Sp1/NF-κB Pathways.

Published in:

Korean Journal of Physiology & Pharmacology, 2015, v. 19, n. 3, p. 263, doi. 10.4196/kjpp.2015.19.3.263

By:

Seung Jin Lee;
Kyo Won Seo;
Chi Dae Kim

Publication type:

Article

miR-502-5p inhibits the proliferation, migration and invasion of gastric cancer cells by targeting SP1.

Published in:

Oncology Letters, 2020, v. 20, n. 3, p. 2757, doi. 10.3892/ol.2020.11808

By:

Peng, Xiaobo;
Wu, Meihong;
Liu, Wuxia;
Guo, Chengtao;
Zhan, Lixing;
Zhan, Xianbao

Publication type:

Article

Tumor-suppressing effects of microRNA-429 in human renal cell carcinoma via the downregulation of Sp1.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2906, doi. 10.3892/ol.2016.4953

By:

DEYAO WU;
XIAOBING NIU;
HUIXING PAN;
YUNFENG ZHOU;
ZICHUN ZHANG;
PING QU;
JIAN ZHOU

Publication type:

Article

The impact of high co-expression of Sp1 and HIF1α on prognosis of patients with hepatocellular cancer.

Published in:

Oncology Letters, 2016, v. 12, n. 1, p. 504, doi. 10.3892/ol.2016.4634

By:

LIANG LIU;
PING JI;
NING QU;
WEI-LIN PU;
DAO-WEN JIANG;
WEI-YAN LIU;
YAQI LI;
RONG-LIANG SHI

Publication type:

Article

Role of transcription factors in porcine reproductive and respiratory syndrome virus infection: A review.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 01, doi. 10.3389/fmicb.2022.924004

By:

Xiangbin You;
Ying Lei;
Ping Zhang;
Dequan Xu;
Ahmed, Zulfiqar;
Youbing Yang

Publication type:

Article

Sp1-Induced lncRNA Rmrp Promotes Mesangial Cell Proliferation and Fibrosis in Diabetic Nephropathy by Modulating the miR-1a-3p/JunD Pathway.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.690784

By:

Yang, Hansen;
Wang, Jia;
Zhang, Zheng;
Peng, Rui;
Lv, Dan;
Liu, Handeng;
Sun, Yan

Publication type:

Article

DNA Methylation of Pig FUT3 Promoter Alters mRNA Expression to Regulate E. coli F18 Susceptibility.

Published in:

Genes, 2021, v. 12, n. 10, p. 1586, doi. 10.3390/genes12101586

By:

Wu, Zhengchang;
Shi, Dongfeng;
Jin, Jian;
Fan, Hairui;
Bao, Wenbin;
Wu, Shenglong

Publication type:

Article

Sp1 -Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7.

Published in:

Genes, 2021, v. 12, n. 5, p. 696, doi. 10.3390/genes12050696

By:

Yan, Junyu;
Yang, Yalan;
Fan, Xinhao;
Tang, Yijie;
Tang, Zhonglin;
Kontos, Christos K.

Publication type:

Article

Regulatory Effect of Methylation of the Porcine AQP3 Gene Promoter Region on Its Expression Level and Porcine Epidemic Diarrhea Virus Resistance.

Published in:

Genes, 2020, v. 11, n. 10, p. 1167, doi. 10.3390/genes11101167

By:

Wu, Jia-Yun;
Wang, Fang;
Wu, Zheng-Chang;
Wu, Sheng-Long;
Bao, Wen-Bin

Publication type:

Article

Sp1 Mediates the Constitutive Expression and Repression of the PDSS2 Gene in Lung Cancer Cells.

Published in:

Genes, 2019, v. 10, n. 12, p. 977, doi. 10.3390/genes10120977

By:

Hu, Lanyue;
Chen, Quanmei;
Wang, Yitao;
Zhang, Na;
Meng, Peixin;
Liu, Tong;
Bu, Youquan

Publication type:

Article

SP1-Mediated Upregulation of lncRNA LINC01614 Functions a ceRNA for miR-383 to Facilitate Glioma Progression Through Regulation of ADAM12.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 4305, doi. 10.2147/OTT.S242854

By:

Wang, Hao;
Wu, Jiang;
Guo, Wei

Publication type:

Article

Regulation of LRRK2 promoter activity and gene expression by Sp1.

Published in:

Molecular Brain, 2016, v. 9, p. 1, doi. 10.1186/s13041-016-0215-5

By:

Juelu Wang;
Weihong Song

Publication type:

Article

Maximal Expression of the Evolutionarily Conserved Slit2 Gene Promoter Requires Sp1.

Published in:

Cellular & Molecular Neurobiology, 2016, v. 36, n. 6, p. 955, doi. 10.1007/s10571-015-0281-8

By:

Saunders, Jacquelyn;
Wisidagama, D.;
Morford, Travis;
Malone, Cindy

Publication type:

Article

Transcriptional Regulators in the Cerebellum in Chronic Schizophrenia: Novel Possible Targets for Pharmacological Interventions.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3653, doi. 10.3390/ijms26083653

By:

Vera-Montecinos, América;
Ramos, Belén

Publication type:

Article

Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-796

By:

Schwarzenbach, Heidi;
Eichelser, Corinna;
Steinbach, Bettina;
Tadewaldt, Josefine;
Pantel, Klaus;
Lobanenkov, Victor;
Loukinov, Dmitri

Publication type:

Article

Functional relevance of promoter CpG island of human Angiotensin II type 1 receptor (AT1R) gene.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 457, n. 1/2, p. 31, doi. 10.1007/s11010-019-03509-8

By:

Chaudhary, Mayank;
Chaudhary, Shashi

Publication type:

Article

Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 455, n. 1/2, p. 73, doi. 10.1007/s11010-018-3471-0

By:

Chatterjee, Biji;
Ghosh, Krishna;
Suresh, Lavanya;
Kanade, Santosh R.

Publication type:

Article

Transcription factor Sp1 prevents TRF2-induced premature senescence in human diploid fibroblasts.

Published in:

Molecular & Cellular Biochemistry, 2016, v. 414, n. 1/2, p. 201, doi. 10.1007/s11010-016-2672-7

By:

An, Hyun;
Lee, Hyeon;
Jang, Suhwa;
Jung, Yu-Jin;
Choi, Sun;
Park, Sang;
Han, Jeong

Publication type:

Article

Roles of miRNA-24 in regulating endothelial nitric oxide synthase expression and vascular endothelial cell proliferation.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 405, n. 1/2, p. 281, doi. 10.1007/s11010-015-2418-y

By:

Zhang, Wenyu;
Li, Yumei;
Chen, Wei;
Hu, Nan;
Wang, Hui;
Ou, Hesheng;
Yan, Limei

Publication type:

Article

Ursolic acid inhibited growth of hepatocellular carcinoma HepG2 cells through AMPKα-mediated reduction of DNA methyltransferase 1.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 402, n. 1/2, p. 63, doi. 10.1007/s11010-014-2314-x

By:

Yie, Yinyi;
Hann, Swei;
Zhao, Shunyu;
Tang, Qin;
Zheng, Fang;
Wu, Jingjing;
Yang, LiJuan;
Deng, ShiGuan

Publication type:

Article

Esculetin promotes type I procollagen expression in human dermal fibroblasts through MAPK and PI3K/Akt pathways.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 368, n. 1/2, p. 61, doi. 10.1007/s11010-012-1342-7

By:

Park, Jung;
Kim, So;
An, Hyun;
Kim, Woo;
Choe, Myeon;
Han, Jeong

Publication type:

Article

Identification of rs2736099 as a novel cis-regulatory variation for TERT and implications for tumorigenesis and cell proliferation.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 8, p. 4515, doi. 10.1007/s00432-022-04372-9

By:

Shi, Qiang;
Zhang, Xin-Xin;
Shi, Xiao-Qian;
Chen, Ying;
Sun, Chang

Publication type:

Article

MiR-6872 host gene SEMA3B and its antisense lncRNA SEMA3B-AS1 function synergistically to suppress gastric cardia adenocarcinoma progression.

Published in:

Gastric Cancer, 2019, v. 22, n. 4, p. 705, doi. 10.1007/s10120-019-00924-0

By:

Guo, Wei;
Liang, Xiaoliang;
Liu, Lei;
Guo, Yanli;
Shen, Supeng;
Liang, Jia;
Dong, Zhiming

Publication type:

Article

NZ28-induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells.

Published in:

Cancer Immunology, Immunotherapy, 2015, v. 64, n. 5, p. 599, doi. 10.1007/s00262-015-1665-9

By:

Schilling, Daniela;
Kühnel, Annett;
Tetzlaff, Fabian;
Konrad, Sarah;
Multhoff, Gabriele

Publication type:

Article

Transcription factor Sp1 is upregulated by PKCι to drive the expression of YAP1 during pancreatic carcinogenesis.

Published in:

Carcinogenesis, 2021, v. 42, n. 3, p. 344, doi. 10.1093/carcin/bgaa113

By:

Yang, Jinhe;
Wang, Junli;
Zhang, Hongmei;
Li, Changlong;
Chen, Changyan;
Zhu, Tongbo

Publication type:

Article

JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer.

Published in:

Carcinogenesis, 2014, v. 35, n. 2, p. 442, doi. 10.1093/carcin/bgt311

By:

Chen, Yansu;
Huang, Yefei;
Huang, Yulin;
Xia, Xiaowei;
Zhang, Jianbing;
Zhou, Yan;
Tan, Yongfei;
He, Song;
Qiang, Fulin;
Li, Aiping;
Re, Oluf Dimitri;
Li, Gang;
Zhou, Jianwei

Publication type:

Article

ZEB2–Sp1 cooperation induces invasion by upregulating cadherin-11 and integrin α5 expression.

Published in:

Carcinogenesis, 2014, v. 35, n. 2, p. 302, doi. 10.1093/carcin/bgt340

By:

Nam, Eun-Hee;
Lee, Yunhee;
Zhao, Xue-Feng;
Park, Young-Kyu;
Lee, Jung Weon;
Kim, Semi

Publication type:

Article

Hypoxia inducible factor 1 alpha down-regulates type i collagen through Sp3 transcription factor in human chondrocytes.

Published in:

IUBMB Life, 2016, v. 68, n. 9, p. 756, doi. 10.1002/iub.1539

By:

Duval, Elise;
Bouyoucef, Mouloud;
Leclercq, Sylvain;
Baugé, Catherine;
Boumédiene, Karim

Publication type:

Article

Transcriptional repressor REST drives lineage stage–specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma.

Published in:

Science Signaling, 2019, v. 12, n. 565, p. N.PAG, doi. 10.1126/scisignal.aan8680

By:

Dobson, Tara H. W.;
Tao, Rong-Hua;
Swaminathan, Jyothishmathi;
Maegawa, Shinji;
Shaik, Shavali;
Bravo-Alegria, Javiera;
Sharma, Ajay;
Kennis, Bridget;
Yang, Yanwen;
Callegari, Keri;
Haltom, Amanda R.;
Taylor, Pete;
Kogiso, Mari;
Qi, Lin;
Khatua, Soumen;
Goldman, Stewart;
Lulla, Rishi R.;
Fangusaro, Jason;
MacDonald, Tobey J.;
Li, Xiao-Nan

Publication type:

Article

Overexpression of the Transcription Factor Sp1 Activates the OAS-RNAse L-RIG-I Pathway.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118551

By:

Dupuis-Maurin, Valéryane;
Brinza, Lilia;
Baguet, Joël;
Plantamura, Emilie;
Schicklin, Stéphane;
Chambion, Solène;
Macari, Claire;
Tomkowiak, Martine;
Deniaud, Emmanuelle;
Leverrier, Yann;
Marvel, Jacqueline;
Michallet, Marie-Cécile

Publication type:

Article

Identification of Poly(ADP-Ribose) Polymerase-1 as a Cell Cycle Regulator through Modulating Sp1 Mediated Transcription in Human Hepatoma Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082872

By:

Yang, Liu;
Huang, Kun;
Li, Xiangrao;
Du, Meng;
Kang, Xiang;
Luo, Xi;
Gao, Lu;
Wang, Cheng;
Zhang, Yanqing;
Zhang, Chun;
Tong, Qiangsong;
Huang, Kai;
Zhang, Fengxiao;
Huang, Dan

Publication type:

Article

p53 Represses Transcription of RING Finger LIM Domain-Binding Protein RLIM through Sp1

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062832

By:

Kong, Xiangtao;
Peng, Bo;
Yang, Yang;
Zhang, Pingzhao;
Qin, Bo;
Han, Dingding;
Wang, Chenji;
Dang, Yongjun;
Liu, Jun O.;
Yu, Long

Publication type:

Article

Mithramycin Exerts an Anti-Myeloma Effect and Displays Anti-Angiogenic Effects through Up-Regulation of Anti-Angiogenic Factors

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062818

By:

Otjacques, Eléonore;
Binsfeld, Marilène;
Rocks, Natacha;
Blacher, Silvia;
Vanderkerken, Karin;
Noel, Agnès;
Beguin, Yves;
Cataldo, Didier;
Caers, Jo

Publication type:

Article

Activity of the Upstream Component of Tandem TERT/ Survivin Promoters Depends on Features of the Downstream Component.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046474

By:

Alekseenko, Irina V.;
Pleshkan, Victor V.;
Kopantzev, Eugene P.;
Stukacheva, Elena A.;
Chernov, Igor P.;
Vinogradova, Tatyana V.;
Sverdlov, Eugene D.

Publication type:

Article

DNA methylation status of TBX20 in patients with tetralogy of Fallot.

Published in:

BMC Medical Genomics, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s12920-019-0534-3

By:

Gong, Juan;
Sheng, Wei;
Ma, Duan;
Huang, Guoying;
Liu, Fang

Publication type:

Article

miR-1224 contributes to ischemic stroke-mediated natural killer cell dysfunction by targeting Sp1 signaling.

Published in:

2021

By:

Feng, Yan;
Li, Yan;
Zhang, Ying;
Zhang, Bo-Hao;
Zhao, Hui;
Zhao, Xin;
Shi, Fu-Dong;
Jin, Wei-Na;
Zhang, Xiao-An

Publication type:

journal article

Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer.

Published in:

2016

By:

Tetsuro Tominaga;
Tomoshi Tsuchiya;
Koji Mochinaga;
Junichi Arai;
Naoya Yamasaki;
Keitaro Matsumoto;
Takuro Miyazaki;
Toshiya Nagasaki;
Atsushi Nanashima;
Kazuhiro Tsukamoto;
Takeshi Nagayasu;
Tominaga, Tetsuro;
Tsuchiya, Tomoshi;
Mochinaga, Koji;
Arai, Junichi;
Yamasaki, Naoya;
Matsumoto, Keitaro;
Miyazaki, Takuro;
Nagasaki, Toshiya;
Nanashima, Atsushi

Publication type:

journal article

DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma.

Published in:

Molecular Cancer, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12943-020-1137-5

By:

Lu, Chenfei;
Wei, Yutian;
Wang, Xiefeng;
Zhang, Zhuoran;
Yin, Jianxing;
Li, Wentao;
Chen, Lijiu;
Lyu, Xiao;
Shi, Zhumei;
Yan, Wei;
You, Yongping

Publication type:

Article

Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells.

Published in:

PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009311

By:

Ganther, Sean;
Radaic, Allan;
Malone, Erin;
Kamarajan, Pachiyappan;
Chang, Nai-Yuan Nicholas;
Tafolla, Christian;
Zhan, Ling;
Fenno, J. Christopher;
Kapila, Yvonne L.

Publication type:

Article

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.

Published in:

PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008752

By:

Bosso, Matteo;
Prelli Bozzo, Caterina;
Hotter, Dominik;
Volcic, Meta;
Stürzel, Christina M.;
Rammelt, Annika;
Ni, Yi;
Urban, Stephan;
Becker, Miriam;
Schelhaas, Mario;
Wittmann, Sabine;
Christensen, Maria H.;
Schmidt, Florian I.;
Gramberg, Thomas;
Sparrer, Konstantin M. J.;
Sauter, Daniel;
Kirchhoff, Frank

Publication type:

Article

Global human tissue profiling and protein network analysis reveals distinct levels of transcriptional germline-specificity and identifies target genes for male infertility.

Published in:

Human Reproduction, 2012, v. 27, n. 11, p. 3233, doi. 10.1093/humrep/des301

By:

Chalmel, Frédéric;
Lardenois, Aurélie;
Evrard, Bertrand;
Mathieu, Romain;
Feig, Caroline;
Demougin, Philippe;
Gattiker, Alexandre;
Schulze, Wolfgang;
Jégou, Bernard;
Kirchhoff, Christiane;
Primig, Michael

Publication type:

Article

cAMP regulates 11β-hydroxysteroid dehydrogenase-2 and Sp1 expression in MLO-Y4/MC3T3-E1 cells.

Published in:

Experimental & Therapeutic Medicine, 2020, v. 20, n. 3, p. 2166

By:

Liu, Di;
Wang, Yaoqing;
Pan, Zhenyu;
Huang, Zhen;
Chen, Fan

Publication type:

Article

SP1-induced lncRNA MCF2L-AS1 promotes cisplatin resistance in ovarian cancer by regulating IGF2BP1/IGF2/MEK/ERK axis.

Published in:

Journal of Gynecologic Oncology, 2022, v. 33, n. 6, p. 1, doi. 10.3802/jgo.2022.33.e75

By:

Yan Zhu;
Lijuan Yang;
Jianqing Wang;
Yan Li;
Youguo Chen

Publication type:

Article

CRISPR single base editing, neuronal disease modelling and functional genomics for genetic variant analysis: pipeline validation using Kleefstra syndrome EHMT1 haploinsufficiency.

Published in:

Stem Cell Research & Therapy, 2022, v. 13, n. 1, p. 1, doi. 10.1186/s13287-022-02740-3

By:

Fear, Vanessa S.;
Forbes, Catherine A.;
Anderson, Denise;
Rauschert, Sebastian;
Syn, Genevieve;
Shaw, Nicole;
Jamieson, Sarra;
Ward, Michelle;
Baynam, Gareth;
Lassmann, Timo

Publication type:

Article