Works matching DE "TRABECTEDIN"

Results: 120

Pharmacometabolomics of trabectedin in metastatic soft tissue sarcoma patients.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1212634

By:

Corona, Giuseppe;
Di Gregorio, Emanuela;
Buonadonna, Angela;
Lombardi, Davide;
Scalone, Simona;
Steffan, Agostino;
Miolo, Gianmaria

Publication type:

Article

Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00421

By:

Xin Miao;
Koch, Gilbert;
Ait-Oudhia, Sihem;
Straubinger, Robert M.;
Jusko, William J.

Publication type:

Article

Mode of action of trabectedin in myxoid liposarcomas.

Published in:

Oncogene, 2014, v. 33, n. 44, p. 5201, doi. 10.1038/onc.2013.462

By:

Di Giandomenico, S;
Frapolli, R;
Bello, E;
Uboldi, S;
Licandro, S A;
Marchini, S;
Beltrame, L;
Brich, S;
Mauro, V;
Tamborini, E;
Pilotti, S;
Casali, P G;
Grosso, F;
Sanfilippo, R;
Gronchi, A;
Mantovani, R;
Gatta, R;
Galmarini, C M;
Sousa-Faro, J M F;
D'Incalci, M

Publication type:

Article

Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45664-7

By:

Son, Kook;
Takhaveev, Vakil;
Mor, Visesato;
Yu, Hobin;
Dillier, Emma;
Zilio, Nicola;
Püllen, Nikolai J. L.;
Ivanov, Dmitri;
Ulrich, Helle D.;
Sturla, Shana J.;
Schärer, Orlando D.

Publication type:

Article

Hepatoprotective effect of N-acetylcysteine in trabectedin-induced liver toxicity in patients with advanced soft tissue sarcoma.

Published in:

2018

By:

Grisanti, Salvatore;
Cosentini, Deborah;
Tovazzi, Valeria;
Bianchi, Susanna;
Lazzari, Barbara;
Consoli, Francesca;
Roca, Elisa;
Berruti, Alfredo;
Ferrari, Vittorio D

Publication type:

journal article

Emesis and nausea related to single agent trabectedin in ovarian cancer patients: a sub-study of the MITO15 project.

Published in:

2017

By:

Di Napoli, Marilena;
Della Pepa, Chiara;
Arenare, Laura;
Scambia, Giovanni;
Lorusso, Domenica;
Raspagliesi, Francesco;
Ferrandina, Gabriella;
Salutari, Vanda;
Sorio, Roberto;
Mosconi, Anna;
Mangili, Giorgia;
Borgato, Lucia;
Lepori, Stefano;
Salvino, Angela;
Pignata, Sandro;
Cecere, Sabrina;
Mosconi, Anna Maria;
Cecere, Sabrina Chiara

Publication type:

journal article

Activity of TNT: a phase 2 study using talimogene laherparepvec, nivolumab and trabectedin for previously treated patients with advanced sarcomas (NCT# 03886311).

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1116937

By:

Chawla, Sant P.;
Tellez, Walter Andree;
Chomoyan, Hripsime;
Valencia, Chrysler;
Ahari, Amir;
Omelchenko, Nadezhda;
Makrievski, Stefan;
Brigham, Don A.;
Chua-Alcala, Victoria;
Quon, Doris;
Moradkhani, Ania;
Gordon, Erlinda M.

Publication type:

Article

Editorial: Trabectedin, lurbinectedin, and other marine-derived anticancer alkaloids on solid cancer: Mechanisms of action, clinical impact, and future perspectives.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 01, doi. 10.3389/fonc.2022.1115342

By:

Zambelli, Alberto;
D'Incalci, Maurizio

Publication type:

Article

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8- gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.844250

By:

Merlini, Alessandra;
Centomo, Maria Laura;
Ferrero, Giulio;
Chiabotto, Giulia;
Miglio, Umberto;
Berrino, Enrico;
Giordano, Giorgia;
Brusco, Silvia;
Pisacane, Alberto;
Maldi, Elena;
Sarotto, Ivana;
Capozzi, Federica;
Lano, Cristina;
Isella, Claudio;
Crisafulli, Giovanni;
Aglietta, Massimo;
Dei Tos, Angelo Paolo;
Sbaraglia, Marta;
Sangiolo, Dario;
D’Ambrosio, Lorenzo

Publication type:

Article

Cover: Journal of the Chinese Chemical Society 5/2022.

Published in:: Journal of the Chinese Chemical Society, 2022, v. 69, n. 5, p. 769, doi. 10.1002/jccs.202280105
Publication type:: Article

Trabectedin and Radiotherapy in Endometrial Stromal Sarcoma: A Case Report.

Published in:

2024

By:

Carrasco García, Irene;
Benedetti Pedroza, Johana;
Miras Rodriguez, Isabel;
Rincón, Inmaculada

Publication type:

Case Study

A Clear Cell Sarcoma Case: A Diagnostic and Treatment Challenge, with a Promising Response to Trabectedin.

Published in:

Case Reports in Oncology, 2023, v. 16, n. 1, p. 1542, doi. 10.1159/000534935

By:

Galera, Mar;
Álvarez, Rosa;
Arregui, Marta;
Paniagua, Miguel;
Álvarez, Ana;
González Crisostomo, Raphael Angelo;
Díazgranados, Adriana;
Gutiérrez, Natalia;
Calles, Antonio;
Agra, Carolina

Publication type:

Article

Long-Time Progression-Free Survival with Trabectedin in Chemorefractory Metastatic Leiomyosarcoma of the Retroperitoneum: A Case Report.

Published in:

Case Reports in Oncology, 2023, v. 16, n. 1, p. 1013, doi. 10.1159/000533827

By:

Reichinger, Andreas

Publication type:

Article

Trabectedin Cardiotoxicity in Soft Tissue Sarcoma: A Case Series and Clinical Insights.

Published in:

2022

By:

Gent, David G.;
Ali, Nasim;
Olsson-Brown, Anna;
Lip, Gregory Y.H.;
Wright, David J.;
Dobson, Rebecca

Publication type:

Case Study

Long-Lasting Response to Trabectedin in a Patient with Metastatic Uterine Leiomyosarcoma: A Case Report.

Published in:

2018

By:

Nteli, Viktoria-Anna;
Knauf, Wolfgang;
Janton-Klein, Anja;
El-Safadi, Samer

Publication type:

Case Study

Metastatic Intimal Sarcoma of the Pulmonary Artery Sensitive to Carboplatin-Vinorelbine Chemotherapy: Case Report and Literature Review.

Published in:

2018

By:

Cantaloube, Marie;
Moureau-Zabotto, Laurence;
Mescam, Lena;
Monneur, Audrey;
Deluca, Valeria;
Guiramand, Jerome;
Perrot, Delphine;
Bertucci, François

Publication type:

Case Study

Effect of the Combination of Trabectedin and Pegylated Liposomal Doxorubicin in a BRCA2 Mutation Carrier with Recurrent Platinum-Sensitive Ovarian Cancer.

Published in:

2017

By:

Rubio Pérez, María Jesús

Publication type:

Case Study

Efficacy of trabectedin in metastatic solitary fibrous tumor.

Published in:

Rare Tumors, 2011, v. 3, n. 3, p. 92, doi. 10.4081/rt.2011.e29

By:

Chaigneau, Loïc;
Kalbacher, Elsa;
Thiery-Vuillemin, Antoine;
Fagnoni-Legat, Christine;
Isambert, Nicolas;
Aherfi, Lionel;
Pauchot, Julien;
Delroeux, Delphine;
Servagi-Vernat, Stephanie;
Mansi, Laura;
Pivot, Xavier

Publication type:

Article

Acute Myeloid Leukemia Unlikely Related to Trabectedin Treatment.

Published in:

Acta Haematologica, 2011, v. 126, n. 4, p. 238, doi. 10.1159/000330952

By:

Cartoafa, Mirela;
Kahatt, Carmen;
Soto-Matos, Arturo;
Roy, Elena;
Lardelli, Pilar

Publication type:

Article

Reply.

Published in:

Acta Haematologica, 2011, v. 126, n. 4, p. 240, doi. 10.1159/000331465

By:

Liu, Stephen V.;
Douer, Dan

Publication type:

Article

PREPARATION OF 2'-N-2,3,4-TRIFLUOROBENZOYL DERIVATIVE OF CYTOTOXIC ECTEINASCIDIN 770 FROM THE THAI TUNICATE ECTEINASCIDIA THURSTONI.

Published in:

Thai Journal of Pharmaceutical Sciences, 2014, v. 38, p. 8

By:

Lowtangkitcharoen, Witaya;
Chuanasa, Taksina;
Saito, Naoki;
Suwanborirux, Khanit

Publication type:

Article

A Concise and Practical Semisynthesis of Ecteinascidin 743 and (–)-Jorumycin.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 5, p. 975, doi. 10.1002/ejoc.201601409

By:

Xu, Shanghu;
Wang, Guan;
Zhu, Jinjin;
Shen, Chuang;
Yang, Zhezhou;
Yu, Jun;
Li, Zhong;
Lin, Tanghuan;
Sun, Xun;
Zhang, Fuli

Publication type:

Article

BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients.

Published in:

British Journal of Cancer, 2015, v. 112, n. 4, p. 688, doi. 10.1038/bjc.2014.624

By:

Laroche-Clary, A;
Chaire, V;
Le Morvan, V;
Neuville, A;
Bertucci, F;
Salas, S;
Sanfilippo, R;
Pourquier, P;
Italiano, A

Publication type:

Article

Trabectedin, a drug acting on both cancer cells and the tumour microenvironment.

Published in:

British Journal of Cancer, 2014, v. 111, n. 4, p. 646, doi. 10.1038/bjc.2014.149

By:

D'Incalci, M;
Badri, N;
Galmarini, C M;
Allavena, P

Publication type:

Article

Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: a retrospective pooled analysis of five phase II trials.

Published in:

British Journal of Cancer, 2013, v. 109, n. 7, p. 1717, doi. 10.1038/bjc.2013.524

By:

Cesne, A L;
Judson, I;
Maki, R;
Grosso, F;
Schuetze, S;
Mehren, M V;
Chawla, S P;
Demetri, G D;
Nieto, A;
Tanovic, A;
Blay, J-Y

Publication type:

Article

Combined Trabectedin and anti-PD1 antibody produces a synergistic antitumor effect in a murine model of ovarian cancer.

Published in:

Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0613-y

By:

Zhiqiang Guo;
Haolin Wang;
Fandong Meng;
Jie Li;
Shulan Zhang

Publication type:

Article

Mechanism of action of trabectedin in desmoplastic small round cell tumor cells.

Published in:

2017

By:

Uboldi, S.;
Craparotta, I.;
Colella, G.;
Ronchetti, E.;
Beltrame, L.;
Vicario, S.;
Marchini, S.;
Panini, N.;
Dagrada, G.;
Bozzi, F.;
Pilotti, S.;
Galmarini, C. M.;
D'Incalci, M.;
Gatta, R.

Publication type:

journal article

Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma.

Published in:

2016

By:

Hideo Morioka;
Shunji Takahashi;
Nobuhito Araki;
Hideshi Sugiura;
Takafumi Ueda;
Mitsuru Takahashi;
Tsukasa Yonemoto;
Hiroaki Hiraga;
Toru Hiruma;
Toshiyuki Kunisada;
Akihiko Matsumine;
Michiro Susa;
Nakayama, Robert;
Kazumasa Nishimoto;
Kazutaka Kikuta;
Keisuke Horiuchi;
Akira Kawai;
Morioka, Hideo;
Takahashi, Shunji;
Araki, Nobuhito

Publication type:

journal article

Viability of microorganisms in novel chemical and biopharmaceutical anticancer drug solutions.

Published in:

European Journal of Parenteral & Pharmaceutical Sciences, 2015, v. 20, n. 1, p. 5

By:

Sarakbi, Iman;
Federici, Matteo;
Krämer, Irene

Publication type:

Article

Treatment of advanced soft tissue sarcoma: efficacy and safety of trabectedin, a multitarget agent, and update on other systemic therapeutic options.

Published in:

Expert Review of Clinical Pharmacology, 2016, v. 9, n. 4, p. 501, doi. 10.1586/17512433.2016.1152179

By:

Duffaud, Florence;
Maki, Robert G.;
Jones, Robin L.

Publication type:

Article

Trabectedin for L-Type Sarcoma: A Retrospective Multicenter Study.

Published in:

Current Oncology, 2024, v. 31, n. 11, p. 6803, doi. 10.3390/curroncol31110502

By:

Ön, Sercan;
Köksal, Barış;
Arık, Zafer;
Caner, Burcu;
Ercan Uzundal, Duygu;
Yazıcı, Ozan;
Arslan Benli, Burcu;
Eylemer Mocan, Eda;
Güngör, Can;
Güç, Zeynep Gülsüm;
Akay, Seval;
Keskinkılıç, Merve;
Dik Avcı, Hande;
Karaca Yayla, Burçak;
Çakar, Burcu;
Şanlı, Ulus Ali

Publication type:

Article

Diagnostic use of fluorescence in situ hybridization in expert review in a phase 2 study of trabectedin monotherapy in patients with advanced, translocation-related sarcoma.

Published in:

Diagnostic Pathology, 2016, v. 11, p. 1, doi. 10.1186/s13000-016-0486-2

By:

Shintaro Sugita;
Hiroko Asanuma;
Tadashi Hasegawa

Publication type:

Article

Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study.

Published in:

Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-01942-y

By:

Sun, Cheng-Ming;
Toulmonde, Maud;
Spalato-Ceruso, Mariella;
Peyraud, Florent;
Bessede, Alban;
Kind, Michèle;
Cousin, Sophie;
Buy, Xavier;
Palussiere, Jean;
Bougouin, Antoine;
Sautès-Fridman, Catherine;
Fridman, Hervé Wolf;
Pulido, Marina;
Italiano, Antoine

Publication type:

Article

Trabectedin-pegylated liposomal doxorubicin compared to cisplatin desensitization regimen-paclitaxel in ovarian cancer patients.

Published in:

European Journal of Gynaecological Oncology, 2024, v. 45, n. 6, p. 32, doi. 10.22514/ejgo.2024.114

By:

Paulsen, Torbjørn;
Birgisdottir, Alda;
Myklebust, Tor Åge;
Dørum, Anne;
Zahl Eriksson, Ane Gerda;
Vilming, Bente

Publication type:

Article

Confirmatory diagnosis and successive chemotherapeutic treatments of metastatic skeletal EWSR1::NFATC2 sarcoma: A case report.

Published in:

2025

By:

Urasaki, Tetsuya;
Ono, Makiko;
Yamashita, Kyoko;
Tanizawa, Taisuke;
Togashi, Yuki;
Ohmoto, Akihiro;
Suto, Hirotaka;
Oki, Ryosuke;
Wang, Xiaofei;
Nakao, Takehiro;
Sato, Yasuyoshi;
Fukuda, Naoki;
Nakano, Kenji;
Tomomatsu, Junichi;
Saito, Masanori;
Hayakawa, Keiko;
Takeuchi, Kengo;
Matsumoto, Seiichi;
Ae, Keisuke;
Takahashi, Shunji

Publication type:

Case Study

Metastatic extraskeletal Ewing's sarcoma treated with trabectedin: A case report.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2936, doi. 10.3892/ol.2016.4950

By:

HERNANDO-CUBERO, JORGE;
SANZ-MONCASI, PILAR;
HERNÁNDEZ-GARCÍA, ALBA;
PAJARES-BERNARD, ISABEL;
MARTÍNEZ-TRUFERO, JAVIER

Publication type:

Article

Complete remission of a reccurrent mesenteric liposarcoma with rare histological features following the administration of trabectedin.

Published in:

Oncology Letters, 2014, v. 7, n. 1, p. 47, doi. 10.3892/ol.2013.1646

By:

TSOUKALAS, N.;
TOLIA, M.;
LYPAS, G.;
PANOPOULOS, C.;
BARBOUNIS, V.;
KOUMAKIS, G.;
EFREMIDIS, A.

Publication type:

Article

Trabectedin in combination with pegylated liposomal doxorubicin in patients with ovarian tumors.

Published in:

Molecular & Clinical Oncology, 2018, v. 9, n. 6, p. 635, doi. 10.3892/mco.2018.1729

By:

Villanucci, Alessandro;
Tavella, Ketty;
Vannini, Laura;
Rossi, Virginia;
Nobili, Stefania;
Amunni, Gianni;
Mazzei, Teresita;
Mini, Enrico

Publication type:

Article

Systemic inflammation index is a predictive and prognostic factor in patients with liposarcoma or leiomyosarcoma treated with trabectedin.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-89977-z

By:

Sobczuk, Pawel;
Filipowicz, Paulina;
Lamparski, Lukasz;
Kosela-Paterczyk, Hanna;
Teterycz, Pawel;
Kozak, Katarzyna;
Rogala, Paweł;
Świtaj, Tomasz;
Falkowski, Sławomir;
Rutkowski, Piotr

Publication type:

Article

From seaside to bedside: Current evidence and future perspectives in the treatment of breast cancer using marine compounds.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.909566

By:

De Sanctis, Rita;
Jacobs, Flavia;
Benvenuti, Chiara;
Gaudio, Mariangela;
Franceschini, Raul;
Tancredi, Richard;
Pedrazzoli, Paolo;
Santoro, Armando;
Zambelli, Alberto

Publication type:

Article

Determination of Extravasation Effects of Nal-Iri and Trabectedin and Evaluation of Treatment Options for Trabectedin Extravasation in a Preclinical Animal Model.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.875695

By:

Keritam, Omar;
Juhasz, Viktoria;
Schöfer, Christian;
Thallinger, Christiane;
Aretin, Marie-Bernadette;
Schabbauer, Gernot;
Breuss, Johannes;
Unseld, Matthias;
Uhrin, Pavel

Publication type:

Article

The Role of Trabectedin in Soft Tissue Sarcoma.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.777872

By:

Nakamura, Tomoki;
Sudo, Akihiro

Publication type:

Article

Trabectedin as single agent in relapsed advanced ovarian cancer: results from a retrospective pooled analysis of three phase II trials.

Published in:

Medical Oncology, 2013, v. 30, n. 1, p. 1, doi. 10.1007/s12032-012-0435-1

By:

Campo, José;
Sessa, Cristiana;
Krasner, Carolyn;
Vermorken, Jan;
Colombo, Nicoletta;
Kaye, Stan;
Gore, Martin;
Zintl, Patrik;
Gómez, Javier;
Parekh, Trilok;
Park, Youn;
McMeekin, Scott

Publication type:

Article

Phase I and pharmacokinetic study of trabectedin 3-hour infusion every three weeks in patients with advanced cancer and alteration of hepatic function.

Published in:

Medical Oncology, 2012, v. 29, n. 3, p. 2240, doi. 10.1007/s12032-011-9979-8

By:

Pardo, Beatriz;
Salazar, Ramón;
Ciruelos, Eva;
Cortés-Funes, Hernán;
García, Margarita;
Majem, Margarita;
Montes, Ana;
Cuadra, Carmen;
Soto-Matos, Arturo;
Lebedinsky, Claudia;
Alfaro, Vicente;
Paz-Ares, Luis

Publication type:

Article

Activity of trabectidin in desmoplastic small round cell tumor.

Published in:

Medical Oncology, 2011, v. 28, p. 644, doi. 10.1007/s12032-010-9687-9

By:

López-González, Ana;
Cantos, Blanca;
Tejerina, Eva;
Provencio, Mariano

Publication type:

Article

Clinical practice guidelines for uterine corpus cancer: an update to the Korean Society of Gynecologic Oncology guidelines.

Published in:

Journal of Gynecologic Oncology, 2025, v. 36, n. 1, p. 1, doi. 10.3802/jgo.2025.36.e71

By:

Woo Yeon Hwang;
Ju-Hyun Kim;
Noh, Joseph J.;
Min-Hyun Baek;
Min Chul Choi;
Yong Jae Lee;
Lee, Maria;
Dong Hoon Suh;
Yong Beom Kim;
Dae-Yeon Kim

Publication type:

Article

Synergetic approaches of fucoidan and trabectedin complex coated PLGA nanoparticles effectively suppresses proliferation and induce apoptosis for the treatment on non-small cell lung cancer.

Published in:

Journal of Biomaterials Science -- Polymer Edition, 2024, v. 35, n. 9, p. 1323, doi. 10.1080/09205063.2024.2328421

By:

Fang, Qingliang;
Mao, Guangmin;
Wang, Lei;
Gu, Yukai;
Song, Renjie;
Gu, Xianglian;
Lu, Song;
Li, Xiaoli

Publication type:

Article

Trabectedin use in soft‐tissue sarcoma patients in a real‐world setting: Data from an Italian national drug‐access registry.

Published in:

International Journal of Cancer, 2023, v. 152, n. 4, p. 761, doi. 10.1002/ijc.34309

By:

Vincenzi, Bruno;
Napolitano, Andrea;
Comandone, Alessandro;
Sanfilippo, Roberta;
Celant, Simone;
Olimpieri, Pier P.;
Di Segni, Susanna;
Russo, Pierluigi;
Casali, Paolo G.

Publication type:

Article

Trabectedin has promising antineoplastic activity in high-grade meningioma.

Published in:

Cancer (0008543X), 2012, v. 118, n. 20, p. 5038, doi. 10.1002/cncr.27460

By:

Preusser, Matthias;
Spiegl-Kreinecker, Sabine;
Lötsch, Daniela;
Wöhrer, Adelheid;
Schmook, Maria;
Dieckmann, Karin;
Saringer, Walter;
Marosi, Christine;
Berger, Walter

Publication type:

Article

Complete response of a recurrent-metastatic liposarcoma with dedifferentiated histological features following the administration of trabectedin and review of literature.

Published in:

2015

By:

Kus, Tulay;
Aktas, Gokmen;
Kalender, Mehmet Emin;
Tutar, Ediz;
Ulker, Esra;
Camci, Celaletdin

Publication type:

Case Study