Works about TOPOTECAN

Results: 293

Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 3, p. 613, doi. 10.1007/s11060-011-0629-y

By:

Lin, Nancy;
Eierman, Wolfgang;
Greil, Richard;
Campone, Mario;
Kaufman, Bella;
Steplewski, Klaudia;
Lane, Stephen;
Zembryki, Denise;
Rubin, Stephen;
Winer, Eric

Publication type:

Article

Topotecan and ifosfamide systemic chemotherapy for CNS involvement of solid tumors.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 3, p. 629, doi. 10.1007/s11060-010-0434-z

By:

Kiewe, Philipp;
Thiel, Eckhard;
Reinwald, Mark;
Korfel, Agnieszka

Publication type:

Article

Phase II Study on Weekly Bolus Topotecan in Advanced or Recurrent Cervical Cancer.

Published in:

Oncology, 2011, v. 80, n. 5/6, p. 390, doi. 10.1159/000330537

By:

Lorusso, D.;
Mainenti, S.;
Pietragalla, A.;
Fusco, E.;
Malaguti, P.;
Masciullo, V.;
Scambia, G.

Publication type:

Article

A sensitive surfactant-mediated spectrofluorimetric determination of chemotherapeutic agent topotecan in human serum and its investigation of DNA binding mechanism.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 3, p. 697, doi. 10.29228/jrp.167

By:

ER, Engin

Publication type:

Article

Recent treatment patterns and real-world survival following first-line anti-PD-L1 treatment for extensive-stage small cell lung cancer.

Published in:

Oncologist, 2024, v. 29, n. 12, p. 1079, doi. 10.1093/oncolo/oyae234

By:

Shaw, Jaime;
Pundole, Xerxes;
Balasubramanian, Akhila;
Anderson, Erik S;
Pastel, Malaika;
Bebb, D Gwyn;
Jiang, Tony;
Martinez, Pablo;
Ramalingam, Suresh S;
Borghaei, Hossein

Publication type:

Article

A Phase Ib Dose-Escalation Study of LCL161 Plus Oral Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies.

Published in:

Oncologist, 2023, v. 28, n. 7, p. 640, doi. 10.1093/oncolo/oyad029

By:

Johnson, Melissa L;
Patel, Manish R;
Aljumaily, Raid;
Jones, Suzanne F;
Burris, Howard A;
Spigel, David R

Publication type:

Article

A Randomized Phase II Study of Linsitinib (OSI-906) Versus Topotecan in Patients With Relapsed Small-Cell Lung Cancer.

Published in:

Oncologist, 2016, v. 21, n. 10, p. 1163, doi. 10.1634/theoncologist.2016-0220

By:

Chiappori, Alberto A.;
Otterson, Gregory A.;
Dowlati, Afshin;
Traynor, Anne M.;
Horn, Leora;
Owonikoko, Taofeek K.;
Ross, Helen J.;
Hann, Christine L.;
Abu Hejleh, Taher;
Nieva, Jorge;
Zhao, Xiuhua;
Schell, Michael;
Sullivan, Daniel M.

Publication type:

Article

Results of Vincristine, Cyclophosphamide and Topotecan Protocol in Refractory/Relapsed Pediatric Solid Tumors: A Single-center Experience.

Published in:

Journal of Pediatric Research, 2019, v. 6, n. 3, p. 197, doi. 10.4274/jpr.galenos.2018.80774

By:

Demirsoy, Uğur;
Çorapçıoğlu, Funda;
Karadoğan, Meriban

Publication type:

Article

Supercritical Fluid Extraction of Camptothecin from Nothapodytes Foetida.

Published in:

Journal of the Chinese Chemical Society, 2014, v. 61, n. 7, p. 778, doi. 10.1002/jccs.201300631

By:

Chu, Fu-Min;
Chang, Kai-Ti;
Chen, Kau-Ming;
Wei, Guor-Tzo

Publication type:

Article

The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids.

Published in:

2007

By:

Holland, M. L.;
Lau, D. T. T.;
Allen, J. D.;
Arnold, J. C.

Publication type:

journal article

The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).

Published in:

2007

By:

Hardwick, L. J. A.;
Velamakanni, S.;
van Veen, H. W.

Publication type:

journal article

Topotecan-Vincristine-Doxorubicin in Stage 4 High-Risk Neuroblastoma Patients Failing to Achieve a Complete Metastatic Response to Rapid COJEC: A SIOPEN Study.

Published in:

Cancer Research & Treatment, 2018, v. 50, n. 1, p. 148, doi. 10.4143/crt.2016.511

By:

Amoroso, Loredana;
Erminio, Giovanni;
Makin, Guy;
Pearson, Andrew D. J.;
Brock, Penelope;
Valteau-Couanet, Dominique;
Castel, Victoria;
Pasquet, Marlène;
Laureys, Genevieve;
Thomas, Caroline;
Luksch, Roberto;
Ladenstein, Ruth;
Haupt, Riccardo;
Garaventa, Alberto

Publication type:

Article

Electrocatalytic N–C–N coupling over a hierarchically ordered open single-atom superstructure toward organonitrogen synthesis.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58948-3

By:

He, Yingchun;
Ma, Dong-Dong;
Ma, Ke;
Li, Xiaofang;
Han, Lili;
Wu, Xin-Tao;
Zhu, Qi-Long

Publication type:

Article

Treatment of Leptomeningeal Carcinomatosis in a Patient with Metastatic Pancreatic Cancer: A Case Report and Review of the Literature.

Published in:

Case Reports in Oncology, 2018, v. 11, n. 2, p. 281, doi. 10.1159/000489085

By:

Johnson, William Rainey;
Theeler, Brett J.;
Echo, David Van;
Young, Patrick;
Mary Kwok

Publication type:

Article

Myeloablative Chemotherapy with Autologous Stem Cell Transplant for Desmoplastic Small Round Cell Tumor.

Published in:

Sarcoma, 2015, v. 2015, p. 1, doi. 10.1155/2015/269197

By:

Forlenza, Christopher J.;
Kushner, Brian H.;
Kernan, Nancy;
Boulad, Farid;
Magnan, Heather;
Wexler, Leonard;
Wolden, Suzanne L.;
LaQuaglia, Michael P.;
Modak, Shakeel

Publication type:

Article

Rapid Screening of Novel Agents for Combination Therapy in Sarcomas.

Published in:

Sarcoma, 2013, p. 1, doi. 10.1155/2013/365723

By:

Cubitt, Christopher L.;
Menth, Jiliana;
Dawson, Jana;
Martinez, Gary V.;
Foroutan, Parastou;
Morse, David L.;
Bui, MarilynM.;
Letson, G. Douglas;
Sullivan, Daniel M.;
Reed, Damon R.

Publication type:

Article

Topotecan and Cyclophosphamide in Adults with Relapsed Sarcoma.

Published in:

Sarcoma, 2012, p. 1, doi. 10.1155/2012/749067

By:

Blanchette, P.;
Hogg, D.;
Ferguson, P.;
Wunder, J. S.;
Swallow, C.;
Gladdy, R.;
Chung, P.;
O'Sullivan, B.;
Blackstein, M. E.;
Catton, C.;
Gupta, A. A.

Publication type:

Article

Phase II study of pazopanib with oral topotecan in patients with metastatic and non-resectable soft tissue and bone sarcomas.

Published in:

2021

By:

Schulte, Brian;
Mohindra, Nisha;
Milhem, Mohammed;
Attia, Steven;
Robinson, Steven;
Monga, Varun;
Hirbe, Angela C.;
Oppelt, Peter;
Charlson, John;
Helenowski, Irene;
Abbinanti, Susan;
Cehic, Rasima;
Okuno, Scott;
Van Tine, Brian A.;
Agulnik, Mark

Publication type:

journal article

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.

Published in:

2021

By:

Yan, Shunfei;
Xuan, Jiachen;
Brajanovski, Natalie;
Tancock, Madeleine R. C.;
Madhamshettiwar, Piyush B.;
Simpson, Kaylene J.;
Ellis, Sarah;
Kang, Jian;
Cullinane, Carleen;
Sheppard, Karen E.;
Hannan, Katherine M.;
Hannan, Ross D.;
Sanij, Elaine;
Pearson, Richard B.;
Chan, Keefe T.

Publication type:

journal article

A multicentre, randomised, open-label, parallel-group Phase 2b study of belotecan versus topotecan for recurrent ovarian cancer.

Published in:

2021

By:

Kim, Hee Seung;
Park, Sang-Yoon;
Park, Chan-Yong;
Kim, Young Tae;
Kim, Beob-Jong;
Song, Yong Jung;
Kim, Byoung-Gie;
Kim, Yong Beom;
Cho, Chi-Heum;
Kim, Jong-Hyeok;
Song, Yong Sang

Publication type:

journal article

Phase I and pharmacological study of pazopanib in combination with oral topotecan in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2015, v. 113, n. 5, p. 706, doi. 10.1038/bjc.2015.257

By:

Kerklaan, B Milojkovic;
Lolkema, M P J;
Devriese, L A;
Voest, E E;
Nol-Boekel, A;
Mergui-Roelvink, M;
Langenberg, M;
Mykulowycz, K;
Stoebenau, J;
Lane, S;
Legenne, P;
Wissel, P;
Smith, D A;
Giantonio, B J;
Schellens, J H M;
Witteveen, P O

Publication type:

Article

Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells.

Published in:

British Journal of Cancer, 2014, v. 110, n. 12, p. 2865, doi. 10.1038/bjc.2014.269

By:

Mancini, M;
Gariboldi, M B;
Taiana, E;
Bonzi, M C;
Craparotta, I;
Pagin, M;
Monti, E

Publication type:

Article

Randomized study of sequential cisplatin-topotecan/carboplatin-paclitaxel versus carboplatin-paclitaxel: effects on quality of life.

Published in:

2016

By:

Brotto, Lori;
Brundage, Michael;
Hoskins, Paul;
Vergote, Ignace;
Cervantes, Andres;
Casado, Herraez;
Poveda, A.;
Eisenhauer, Elizabeth;
Tu, Dongsheng;
Casado, Herraez A;
Gynecologic Cancer Intergroup Study of the NCIC Clinical Trials Group (NCIC CTG), the European Organization for Research and Treatment of Cancer—Gynecologic Cancer Group (EORTC-GCG) and the Grupo de Investigación de Cáncer de Ovario;
Gynecologic Cancer Intergroup Study of NCIC Clinical Trials Group (NCIC CTG);
European Organization for Research and Treatment of Cancer - Gynecologic Cancer Group (EORTC-GCG);
Grupo de Investigación de Cáncer de Ovario (GEICO)

Publication type:

journal article

Second Line Treatment Choice in Extensive Small Lung Cancer.

Published in:

Eurasian Journal of Medical Investigation, 2022, v. 6, n. 4, p. 456, doi. 10.14744/ejmi.2022.72208

By:

Ay, Seval;
Ozyukseler, Deniz Tataroglu;
Dulgar, Ozgecan;
Atci, Muhammed Mustafa;
Arikan, Rukiye;
Akbiyik, Ayten Guner;
Gumus, Mahmut

Publication type:

Article

Continuous-Infusion Topotecan and Erlotinib: A Study in Topotecan-Pretreated Ovarian Cancer Assessing Shed Collagen Epitopes as aMarker of Invasiveness.

Published in:

Oncologist, 2014, v. 19, n. 3, p. 250, doi. 10.1634/theoncologist.2013-0398

By:

Warner, Eiran;
Liebes, Leonard;
Levinson, Benjamin;
Downey, Andrea;
Tiersten, Amy;
Muggia, Franco

Publication type:

Article

A Phase I Study of Weekly Topotecan in Combination with Pemetrexed in Patients with Advanced Malignancies.

Published in:

Oncologist, 2010, v. 15, n. 9, p. 954, doi. 10.1634/theoncologist.2010-0006

By:

BURRIS III, HOWARD A.;
INFANTE, JEFFREY R.;
JEWELL, ROXANNE C.;
SPIGEL, DAVID R.;
GRECO, F. ANTHONY;
THOMPSON, DANA S.;
JONES, SUZANNE F.

Publication type:

Article

Intra‐CSF topotecan in treatment of breast cancer patients with leptomeningeal metastases.

Published in:

Cancer Medicine, 2020, v. 9, n. 21, p. 7935, doi. 10.1002/cam4.3422

By:

Jaeckle, Kurt A.;
Dixon, Jesse G.;
Anderson, Stephen Keith;
Moreno‐Aspitia, Alvaro;
Colon‐Otero, Gerardo;
Hebenstreit, Kathy;
Patel, Tejal A.;
Reddy, Samarth L.;
Perez, Edith A.

Publication type:

Article

Optimization of liposomal topotecan for use in treating neuroblastoma.

Published in:

Cancer Medicine, 2017, v. 6, n. 6, p. 1240, doi. 10.1002/cam4.1083

By:

Chernov, Lina;
Deyell, Rebecca J.;
Anantha, Malathi;
Dos Santos, Nancy;
Gilabert ‐ Oriol, Roger;
Bally, Marcel B.

Publication type:

Article

Efficacy of topotecan in pretreated metastatic poorly differentiated extrapulmonary neuroendocrine carcinoma.

Published in:

Cancer Medicine, 2016, v. 5, n. 9, p. 2261, doi. 10.1002/cam4.807

By:

Apostolidis, Leonidas;
Bergmann, Frank;
Jäger, Dirk;
Winkler, Eva Caroline

Publication type:

Article

Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies.

Published in:

Cancer Medicine, 2016, v. 5, n. 2, p. 294, doi. 10.1002/cam4.598

By:

Reed, Damon R.;
Mascarenhas, Leo;
Manning, Kathleen;
Hale, Gregory A.;
Goldberg, John;
Gill, Jonathan;
Sandler, Eric;
Isakoff, Michael S.;
Smith, Tiffany;
Caracciolo, Jamie;
Lush, Richard M.;
Juan, Tzu‐Hua;
Lee, Jae K.;
Neuger, Anthony M.;
Sullivan, Daniel M.

Publication type:

Article

Inhibition of angiogenic activity of hypoxic fibroblast cell line MRC-5 in vitro by topotecan.

Published in:

Medical Oncology, 2011, v. 28, p. 653, doi. 10.1007/s12032-010-9710-1

By:

Zhou, Liqiang;
Sun, Li;
Lin, Sensen;
Fang, Dongdong;
Zhao, Renping;
Zhu, Jing;
Liu, Jin;
Chen, Liang;
Shi, Wenting;
Yuan, Shengtao;
Zhu, Danni

Publication type:

Article

Multiple myeloma emerging after chemotherapy for non-small-cell lung cancer.

Published in:

2008

By:

Marinopoulos, Spyridon;
Skorda, Lamprini;
Karatapanis, Stylianos;
Rasidakis, Antonis

Publication type:

journal article

Phase I/II study of IV topotecan in combination with whole brain radiation for the treatment of brain metastases.

Published in:

2007

By:

Mirmiran, Alireza;
McClay, Edward;
Spear, Matthew A

Publication type:

journal article

Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24651-2

By:

Yu, Qin;
Ni, Dongchun;
Kowal, Julia;
Manolaridis, Ioannis;
Jackson, Scott M.;
Stahlberg, Henning;
Locher, Kaspar P.

Publication type:

Article

Activity of topotecan 21-day infusion in patients with previously treated large cell lymphoma: long-term follow-up of an Eastern Cooperative Oncology Group study (E5493).

Published in:

Leukemia & Lymphoma, 2012, v. 53, n. 6, p. 1137, doi. 10.3109/10428194.2011.643406

By:

Wiernik, Peter H.;
Li, Hailun;
Weller, Edie;
Hochster, Howard S.;
Horning, Sandra J.;
Nazeer, Tipu;
Gordon, Leo I.;
Habermann, Thomas M.;
Minniti, Carl J.;
Shapiro, Gary R.;
Cassileth, Peter A.

Publication type:

Article

Comeback for the camptothecins?

Published in:

Leukemia & Lymphoma, 2009, v. 50, n. 12, p. 1914, doi. 10.3109/10428190903291088

By:

Kirschbaum, Mark

Publication type:

Article

Topotecan and Ginkgolic Acid Inhibit the Expression and Transport Activity of Human Organic Anion Transporter 3 by Suppressing SUMOylation of the Transporter.

Published in:

Pharmaceutics, 2024, v. 16, n. 5, p. 638, doi. 10.3390/pharmaceutics16050638

By:

Yu, Zhou;
You, Guofeng

Publication type:

Article

Robust Inclusion Complex of Topotecan Comprised within a Rhodamine-Labeled β-Cyclodextrin: Competing Proton and Energy Transfer Processes.

Published in:

Pharmaceutics, 2023, v. 15, n. 6, p. 1620, doi. 10.3390/pharmaceutics15061620

By:

Di Nunzio, Maria Rosaria;
Douhal, Abderrazzak

Publication type:

Article

Multilayered Polyurethane/Poly(vinyl alcohol) Nanofibrous Mats for Local Topotecan Delivery as a Potential Retinoblastoma Treatment.

Published in:

Pharmaceutics, 2023, v. 15, n. 5, p. 1398, doi. 10.3390/pharmaceutics15051398

By:

Hobzova, Radka;
Sirc, Jakub;
Shrestha, Kusum;
Mudrova, Barbora;
Bosakova, Zuzana;
Slouf, Miroslav;
Munzarova, Marcela;
Hrabeta, Jan;
Feglarova, Tereza;
Cocarta, Ana-Irina

Publication type:

Article

Lactone Stabilized by Crosslinked Cyclodextrin Metal-Organic Frameworks to Improve Local Bioavailability of Topotecan in Lung Cancer.

Published in:

Pharmaceutics, 2023, v. 15, n. 1, p. 142, doi. 10.3390/pharmaceutics15010142

By:

Xiong, Ting;
Guo, Tao;
He, Yaping;
Cao, Zeying;
Xu, Huipeng;
Wu, Wenting;
Wu, Li;
Zhu, Weifeng;
Zhang, Jiwen

Publication type:

Article

The Role of Cryotherapy in Vitreous Concentrations of Topotecan Delivered by Episcleral Hydrogel Implant.

Published in:

Pharmaceutics, 2022, v. 14, n. 5, p. 903, doi. 10.3390/pharmaceutics14050903

By:

Kodetova, Martina;
Hobzova, Radka;
Sirc, Jakub;
Uhlik, Jiri;
Dunovska, Katerina;
Svojgr, Karel;
Cocarta, Ana-Irina;
Felsoova, Andrea;
Slanar, Ondrej;
Sima, Martin;
Kozak, Igor;
Pochop, Pavel

Publication type:

Article

Dual Inhibition of P-gp and BCRP Improves Oral Topotecan Bioavailability in Rodents.

Published in:

Pharmaceutics, 2021, v. 13, n. 4, p. 559, doi. 10.3390/pharmaceutics13040559

By:

Lee, Jaeok;
Kang, Jiyeon;
Kwon, Na-Yun;
Sivaraman, Aneesh;
Naik, Ravi;
Jin, So-Young;
Oh, A. Reum;
Shin, Jae-Ho;
Na, Younghwa;
Lee, Kyeong;
Lee, Hwa-Jeong;
Lee, Yonghyun

Publication type:

Article

Real-Time Positron Emission Tomography Evaluation of Topotecan Brain Kinetics after Ultrasound-Mediated Blood–Brain Barrier Permeability.

Published in:

Pharmaceutics, 2021, v. 13, n. 3, p. 405, doi. 10.3390/pharmaceutics13030405

By:

Molotkov, Andrei;
Carberry, Patrick;
Dolan, Martin A.;
Joseph, Simon;
Idumonyi, Sidney;
Oya, Shunichi;
Castrillon, John;
Konofagou, Elisa E.;
Doubrovin, Mikhail;
Lesser, Glenn J.;
Zanderigo, Francesca;
Mintz, Akiva;
Hosoya, Ken-ichi

Publication type:

Article

Convection Enhanced Delivery of Topotecan for Gliomas: A Single-Center Experience.

Published in:

Pharmaceutics, 2021, v. 13, n. 1, p. 39, doi. 10.3390/pharmaceutics13010039

By:

Upadhyayula, Pavan S.;
Spinazzi, Eleonora F.;
Argenziano, Michael G.;
Canoll, Peter;
Bruce, Jeffrey N.

Publication type:

Article

Transferrin-Conjugated pH-Responsive γ-Cyclodextrin Nanoparticles for Antitumoral Topotecan Delivery.

Published in:

Pharmaceutics, 2020, v. 12, n. 11, p. 1109, doi. 10.3390/pharmaceutics12111109

By:

Yoon, Seonyoung;
Kim, Yoonyoung;
Youn, Yu Seok;
Oh, Kyung Taek;
Kim, Dongin;
Lee, Eun Seong

Publication type:

Article

Pharmacokinetic Comparison of Three Different Administration Routes for Topotecan Hydrochloride in Rats.

Published in:

Pharmaceuticals (14248247), 2020, v. 13, n. 9, p. 231, doi. 10.3390/ph13090231

By:

Jeong, Seung-Hyun;
Jang, Ji-Hun;
Lee, Yong-Bok

Publication type:

Article

Surface contamination of cytotoxic medicine in preparation and patient care areas in Australian hospitals: a retrospective cross‐sectional study.

Published in:

Journal of Pharmacy Practice & Research, 2024, v. 54, n. 4, p. 306, doi. 10.1002/jppr.1925

By:

Woodward, Vincent;
Panjarjian, Meghrie;
Devi, Devika;
Hanrahan, Jane;
Soriano, Michael;
Roper, Matt;
Musa, Hala;
Davies, Stephanie;
Samios, Peter;
Teh, Michael;
Barclay, Peter;
Naughtin, Clare;
Vaillancourt, Régis;
Nikolaidis, Carl;
Pelland, Bryan;
Penm, Jonathan

Publication type:

Article

US SAFETY BRIEFS.

Published in:: Journal of Pharmacy Practice & Research, 2013, v. 43, n. 4, p. 300
Publication type:: Article

Quantification of Unencapsulated Drug in Target Tissues Demonstrates Pharmacological Properties and Therapeutic Effects of Liposomal Topotecan (FF-10850).

Published in:

Pharmaceutical Research, 2024, v. 41, n. 4, p. 795, doi. 10.1007/s11095-023-03652-4

By:

Kimura, Toshifumi;
Okada, Ken;
Morohashi, Yasushi;
Kato, Yukio;
Mori, Mikinaga;
Kato, Hiroshi;
Matsumoto, Takeshi;
Shimoyama, Susumu

Publication type:

Article

SEPARATION, IDENTIFICATION AND QUANTITATION OF DEGRADANTS OF TOPOTECAN AND ITS RELATED IMPURITIES IN TOPOTECAN INJECTION BY RP-HPLC AND LC-MS.

Published in:

Journal of Liquid Chromatography & Related Technologies, 2011, v. 34, n. 7, p. 548, doi. 10.1080/10826076.2011.551610

By:

Raghu, NandanSrinivasan;
Reddy, Y. Ramachandra;
Naresh, V.;
Rao, V. Suryanarayana

Publication type:

Article