Works matching DE "TOLL-like receptors"

Results: 5000

Deciphering TLR and JAK/STAT pathways: genetic variants and targeted therapies in COVID-19.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10843-2

By:

El Houdi, Meriem;
Skhoun, Hanaa;
Guennoun, Aya;
Dakka, Nadia;
Ameziane El Hassani, Rabii;
Ouzzif, Zohra;
El Baghdadi, Jamila

Publication type:

Article

HAX1 inhibits apoptosis and promotes maturation of neutrophils.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02353-2

By:

Yue, Hanwei;
Shi, Guiying;
Tang, Jiaming;
Li, Xinyue;
Bai, Lin

Publication type:

Article

Agmatine Mitigates Acetaminophen-induced Acute Liver Injury in Mice: Involvement of HMGB1/RAGE/NFκB and Nrf2/HO-1 Signaling Pathways.

Published in:

Journal of Applied Veterinary Sciences, 2025, v. 10, n. 3, p. 90, doi. 10.21608/javs.2025.375952.1588

By:

Abdelhady, Ahmed M.;
Ayman, Mohammed;
Abdelmageed, Marwa E.

Publication type:

Article

Toll-like receptor-mediated immune imbalance in asthma: controversies, breakthroughs, and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1605185

By:

Xu, Xinyi;
Yu, Ruihan;
Yang, Zhuoqun;
Li, Chenyu;
Xiong, Huabao;
Li, Chunxia

Publication type:

Article

Lack of Toll-Like Receptor 9 Exacerbates Ocular Impairment and Visual Loss During Systemic Cryptococcus gattii Infection.

Published in:

Journal of Infectious Diseases, 2025, v. 231, n. 6, p. 1597, doi. 10.1093/infdis/jiaf034

By:

Silva-Junior, Elias Barbosa da;
Araújo, Victor Guedes;
Araujo-Silva, Carlla Assis;
Covre, Luciana Polaco;
Guimarães-de-Oliveira, Joyce Cristina;
Diniz-Lima, Israel;
Freire-de-Lima, Leonardo;
Morrot, Alexandre;
Brito-Gitirana, Lycia de;
Previato, Jose Osvaldo;
Mendonça-Previato, Lucia;
Vommaro, Rossiane Claudia;
Petrs-Silva, Hilda;
Decote-Ricardo, Debora;
Guedes, Herbert Leonel de Matos;
Freire-de-Lima, Celio Geraldo

Publication type:

Article

Genetic Variations in TLR2 and TLR4 Genes and Their Association With COVID‐19 Severity and Inflammatory Markers in the Moroccan Population.

Published in:

International Journal of Immunogenetics, 2025, v. 52, n. 4, p. 213, doi. 10.1111/iji.70002

By:

Noureddine, Rachid;
Haddaji, Asmaa;
Baba, Hanâ;
Ouladlahsen, Ahd;
Aqillouch, Safaa;
Laazaazia, Oumaima;
Aainouss, Achraf;
Dehbi, Hind;
Ezzikouri, Sayeh

Publication type:

Article

The influence of immune system-related genes on the development of atopic dermatitis.

Published in:

Advances in Dermatology & Allergology / Postępy Dermatologii i Alergologii, 2025, v. 42, n. 3, p. 232, doi. 10.5114/ada.2025.152114

By:

Cieśla, Dominika;
Nowak, Tomasz

Publication type:

Article

Developmental transcriptomics reveals stage-specific immune gene expression profiles in Spodoptera frugiperda.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06939-1

By:

Wang, Guangmin;
Ran, Jia;
Jia, Chen;
Mohamed, Amr;
Paredes-Montero, Jorge R.;
Al-Akeel, Rasha Khalifah;
Zang, Liansheng;
Zhang, Wei;
Keyhani, Nemat O.;
Eleftherianos, Ioannis

Publication type:

Article

Developmental transcriptomics reveals stage-specific immune gene expression profiles in Spodoptera frugiperda.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06939-1

By:

Wang, Guangmin;
Ran, Jia;
Jia, Chen;
Mohamed, Amr;
Paredes-Montero, Jorge R.;
Al-Akeel, Rasha Khalifah;
Zang, Liansheng;
Zhang, Wei;
Keyhani, Nemat O.;
Eleftherianos, Ioannis

Publication type:

Article

HMGB1 and TLR4 as biomarkers for osteoporosis risk in type 2 diabetes mellitus: a cross-sectional study.

Published in:

BMC Endocrine Disorders, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12902-025-01998-x

By:

Zhu, Guang;
Kan, Chunting;
Cao, Changchun;
Zhu, Hong

Publication type:

Article

Bromodomain-containing protein 4 contributes to chronic postsurgical pain via activating TLR4/NF-kappaB-dependent neuroinflammation.

Published in:

BMC Anesthesiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12871-025-03216-6

By:

Shu, Ruichen;
Li, Yuan;
Zhang, Zengli;
Zhang, Xuan;
Guan, Shan;
Wang, Kaiyuan;
Yin, Yiqing

Publication type:

Article

Clinical Significance and Prognostic Value of TLR4 and AGER in Inflammatory Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2182, doi. 10.3390/cancers17132182

By:

Paiva, Luiza Darla Aguiar Silva;
Teles, Ana Carolina Filgueiras;
Souza, Jeferson dos Santos;
Oliveira, Pedro Ruan Amorim;
Alves, Bianca Elen Souza;
Coelho, Mariana Timbaúba Benício;
Cajado, Aurilene Gomes;
Maia, Isabelle Fátima Vieira Camelo;
Silva, Paulo Goberlânio Barros;
Cavalcante, Diane Isabelle Magno;
Cunha, Maria do Perpétuo Socorro Saldanha;
Arruda, Larissa Mont'Alverne;
Lima-Júnior, Roberto César Pereira;
Rogatto, Silvia Regina;
Wong, Deysi Viviana Tenazoa

Publication type:

Article

Probiotic Bifico Ameliorates Depression- and Anxiety-Like Behaviors Induced by Estrogen Deficiency via NLRP3 Inflammasome Inhibition.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 8153, doi. 10.2147/JIR.S511931

By:

Yu, Xia;
Yu, Xiurong;
Yang, Yang;
Cheng, Wei;
Shi, Mingxiu;
Chen, Li;
Zhang, Xiongle;
Xu, Yongjun

Publication type:

Article

Molecular Study from the Signaling Pathways of Four Potential asthma triggers : AKT1, MAPK13, STAT1, and TLR4.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6240, doi. 10.3390/ijms26136240

By:

Cremades-Jimeno, Lucía;
López-Ramos, María;
Fernández-Santamaría, Rubén;
De Pedro, María Ángeles;
Mahillo, Ignacio;
Rosales-Ariza, Cristina;
Olaguibel, José María;
Pozo, Victoria del;
Caballero, María Luisa;
Luna-Porta, Juan Alberto;
Quirce, Santiago;
Barroso, Blanca;
Betancor, Diana;
Valverde-Monge, Marcela;
Sastre, Joaquín;
Baos, Selene;
Cárdaba, Blanca

Publication type:

Article

Autophagy Differentially Influences Toll-like Receptor 9 and B Cell-Receptor-Mediated B Cell Expansion, Expression of Major Histocompatibility Class II Proteins, and Antigenic Peptide Presentation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6054, doi. 10.3390/ijms26136054

By:

Peddaboina, Chander;
Iannucci, Jaclyn;
Tobin, Richard P.;
Shapiro, Lee A.;
Newell Rogers, M. Karen

Publication type:

Article

Highlights of 2024: The rising role of age‐associated B cells in autoimmune diseases.

Published in:

Immunology & Cell Biology, 2025, v. 103, n. 6, p. 500, doi. 10.1111/imcb.70023

By:

Lee, Adrian YS;
Reed, Joanne H

Publication type:

Article

Toll-like receptor 7 single nucleotide polymorphism rs3853839 in pediatric patients with immune thrombocytopenia.

Published in:

Turkish Journal of Pediatrics, 2025, v. 67, n. 3, p. 349, doi. 10.24953/turkjpediatr.2025.5412

By:

Junlin Wang;
Shuli Wang;
Guijuan Liu;
Han Sun;
Jianqin Li

Publication type:

Article

Milk-derived exosomes exert anti-inflammatory activity in lipopolysaccharide-induced RAW264.7 cells by modulating the TLR4/NF-κB and PI3K/AKT signaling pathways.

Published in:

Experimental & Therapeutic Medicine, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/etm.2025.12899

By:

Cheng, Xinyi;
Sun, Qingying;
Zheng, Rui;
Sun, Yanhao;
Liang, Ziyuan;
Li, Nian;
Deng, Chao

Publication type:

Article

Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09570-2

By:

Ma, Dongxue;
Akthar, Ihshan;
Hashimoto, Taiyo;
Marey, Mohamed A.;
Kusama, Kazuya;
Imakawa, Kazuhiko;
Shimada, Masayuki;
Miyamoto, Akio

Publication type:

Article

Mechanisms of vaccine protection in chickens against challenge with virulent Mycoplasma synoviae.

Published in:

Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01571-3

By:

Kamathewatta, Kanishka I.;
Kanci Condello, Anna;
Shil, Pollob K.;
Noormohammadi, Amir H.;
Young, Neil D.;
Browning, Glenn F.;
Tivendale, Kelly A.;
Wawegama, Nadeeka K.

Publication type:

Article

Mechanism of Neutrophil p90RSK-Nrf2 Signaling Pathway in Atherosclerosis.

Published in:

Balkan Medical Journal, 2025, v. 42, n. 4, p. 347, doi. 10.4274/balkanmedj.galenos.2025.2025-4-73

By:

Jiawen Li;
Lei Wang;
Xiao Liang;
Xiaoxia Li

Publication type:

Article

Important role of long non-coding RNA UBE2R2-AS1 in diabetes-induced renal injury.

Published in:

Archives of Medical Science, 2025, v. 21, n. 2, p. 617, doi. 10.5114/aoms.2020.100649

By:

Chuanqi Chen;
Yanqiong Yan;
Qianjun Luo;
Sufen Li

Publication type:

Article

Extending the IMQ Model: Deep Characterization of the Human TLR7 Response for Early Drug Development.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1366, doi. 10.1007/s10753-024-02127-x

By:

van den Noort, Juliette A.;
Assil, Salma;
Ronner, Micha N.;
Osse, Michelle;
Pot, Iris;
Yavuz, Yalçin;
Damman, Jeffrey;
Lubberts, Erik;
Rissmann, Robert;
der Kolk, Tessa Niemeyer-van;
Tomljanovic, Ingrid;
Jansen, Manon A. A.;
Moerland, Matthijs

Publication type:

Article

Toll-Like Receptor 1/2 Postconditioning by the Ligand Pam3cys Tempers Posttraumatic Hyperexcitability, Neuroinflammation, and Microglial Response: A Potential Candidate for Posttraumatic Epilepsy.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1206, doi. 10.1007/s10753-024-02109-z

By:

Khoshkroodian, Bahar;
Javid, Hanieh;
Pourbadie, Hamid Gholami;
Sayyah, Mohammad

Publication type:

Article

Programmed Death Ligand 1 Modulation by Bacillus Calmette-Guérin and Toll-Like Receptor Agonists in Distinct Breast Cancer Cell Subtypes.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 3401, doi. 10.2147/IJGM.S531858

By:

Barbosa, Gabriela;
Godoy, Maria Carolina Ximenes De;
Bighetto, Caroline Cavalli;
Skakum, Emily Macedo;
Pascoal, Lívia Bitencourt;
Gambero, Alessandra;
Reis, Leonardo O

Publication type:

Article

TLR2 and TLR4 bridge physiological and pathological inflammation in the reproductive system.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08424-x

By:

Mansouri, Alireza;
Akthar, Ihshan;
Miyamoto, Akio

Publication type:

Article

Intratracheal instillation of graphene oxide with different diameters suppressed toll-like receptor 3-mediated lipid droplet biogenesis in lungs and livers of mice.

Published in:

Toxicology Research, 2025, v. 14, n. 3, p. 1, doi. 10.1093/toxres/tfaf069

By:

Wang, Yijin;
Tang, Xiaomin;
Luo, Sihuan;
Zhang, Zhaohui;
Cao, Yi

Publication type:

Article

A humanized anti-Toll like receptor 4 antibody Fab fragment inhibits proinflammatory responses induced by lipopolysaccharide through TLR4 in vitro and in vivo.

Published in:

Journal of Infection in Developing Countries, 2025, v. 19, n. 6, p. 913, doi. 10.3855/jidc.20194

By:

Wenkai Zheng;
Fang Xie;
Shuping Si;
Xi Xiong;
Jing Xu;
Chuanxia Yao;
Cong Li;
Jin Zhu;
Ping Li;
Binggang Cai;
Maorong Wang

Publication type:

Article

Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04976-x

By:

Nonobe, Shuhei;
Okamoto, Hideto;
Ito, Takashi;
Itatani, Hayate;
Yamaki, Ayanori;
Okumura, Nobuaki

Publication type:

Article

Single atom engineering for radiotherapy-activated immune agonist prodrugs.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60768-4

By:

Ding, Zexuan;
Yin, Xiaozhe;
Zheng, Yuedan;
Li, Yiyan;
Ge, Huanhuan;
Feng, Jianshu;
Wang, Ziyang;
Qiao, Simiao;
Sun, Qi;
Yu, Fashuo;
Hou, Zhanshan;
Fu, Yang-Xin;
Liu, Zhibo

Publication type:

Article

Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60678-5

By:

Li, Chenyu;
Adamson, Christopher;
Ng, Allan Wee Ren;
Liang, Yaquan;
Hong, Zebin;
Loh, Jia Tong;
Ng, Siu-Kin;
Kwan, Jeric Mun Chung;
Feng, Shiliu;
Ng, Evan Wei Long;
Nair, Sajith;
Ruedl, Christiane;
Wong, Sunny Hei;
Lam, Kong-Peng;
Qiao, Yuan

Publication type:

Article

Hederasaponin C ameliorates chronic obstructive pulmonary disease pathogenesis by targeting TLR4 to inhibit NF-κB/MAPK signaling pathways.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01155-5

By:

Ning, Yujie;
Huang, Liting;
Wang, Qin-Qin;
Liu, Lina;
Ni, Xinghua;
Xie, Xiaoyun;
Liu, Jingyu;
Su, Qian;
Yang, Shilin;
Yuan, Renyikun;
Gao, Hongwei

Publication type:

Article

Exosomal ITGB2 Mediates Immune Evasion in Triple-Negative Breast Cancer by Suppressing Dendritic Cell Activation via TLR4.

Published in:

Iranian Journal of Public Health, 2025, v. 54, n. 6, p. 1252, doi. 10.18502/ijph.v54i6.18903

By:

Paierhati, Puerkaiti;
Binlin Ma;
Abudukeremu, Muzhapaer

Publication type:

Article

Sitagliptin Mitigates Doxorubicin-Induced Cardiac Toxicity in Rats, Targeting TLR4/NF-Kb Signaling Pathway.

Published in:

Egyptian Journal of Hospital Medicine, 2025, v. 99, n. 1, p. 1445, doi. 10.21608/ejhm.2025.421224

By:

Elmorshdy, Shorouk E. M.;
Khodir, Suzan A.;
El-aziz, Noha M. Abd;
Akl, Ghada Hamdy;
Abdalraouf, Mai M.;
Elfakhrany, Amany Tawfik;
Ahmed, Reem Mohammed;
ossama, Yousra;
El-Sawaf, Eman A.;
Shebl, Ghada Zaghloul;
Shawky, Noha O.;
El Menyawi, Menna Allah I.;
Emam, Reem M.

Publication type:

Article

The Intestinal Thread of Fate: How the Microbiota Shapes the Story of Liver Disease.

Published in:

Livers, 2025, v. 5, n. 2, p. 17, doi. 10.3390/livers5020017

By:

Acierno, Carlo;
Nevola, Riccardo;
Rinaldi, Luca;
Sasso, Ferdinando Carlo;
Adinolfi, Luigi Elio;
Caturano, Alfredo

Publication type:

Article

HMGB1 as a Key Mediator in Malignant Mesothelioma and a Potential Target for Asbestos-Related Cancer Therapy.

Published in:

Toxics, 2025, v. 13, n. 6, p. 448, doi. 10.3390/toxics13060448

By:

Zhong, Yi-Fang;
Ding, Chan;
Yao, Chun-Ji;
Wang, Jia-Chun;
Feng, Min-Qian;
Gong, Xiao-Xue;
Yu, Lin;
Xu, Hua-Dong;
Xia, Hai-Ling

Publication type:

Article

Bladder p75 NTR -Mediated Anti-Inflammatory Response via the TLR4/TRAF6/NF-κB Axis.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 957, doi. 10.3390/life15060957

By:

Covarrubias, Claudia;
Mossa, Abubakr H.;
Yan, Laura R.;
Desormeau, Benjamin;
Cammisotto, Philippe G.;
Saragovi, H. Uri;
Campeau, Lysanne

Publication type:

Article

Genetic Polymorphism of TLR-4 and CD-14 in Patients with Chronic Prostatitis.

Published in:

Medical Journal of Babylon, 2025, v. 22, n. 2, p. 531, doi. 10.4103/MJBL.MJBL_31_24

By:

Al-Jobouri, Worood Ali Mukheef;
Al-Saadi, Mohammed A. K.;
Al-Marzooq, Wadhah Adnan Abbas

Publication type:

Article

Recurrent SARS-CoV-2 Infection Is Linked to the TLR7 rs179008 Variant and Related to Diminished Baseline T Cell Immunity.

Published in:

Immuno, 2025, v. 5, n. 2, p. 17, doi. 10.3390/immuno5020017

By:

Santos, Camilla Natália Oliveira;
dos Santos, Priscila Lima;
da Silva, Angela Maria;
Magalhães, Lucas Sousa

Publication type:

Article

Linking TLR-7 Signaling to Downregulation of Placental P-Glycoprotein: Implications for Fetal Drug Exposure.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 741, doi. 10.3390/pharmaceutics17060741

By:

Riera-Romo, Mario;
McColl, Eliza R;
Piquette-Miller, Micheline

Publication type:

Article

Immunomodulatory Effects of Pulmonarom ® : In Vitro Induction of TLR and Cytokine Expression in Human Dendritic Cells.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 885, doi. 10.3390/ph18060885

By:

Hernández-Aceves, Juan A.;
Solano-Gálvez, Sandra Georgina;
Wilkins-Rodríguez, Arturo A.;
Delgado-Domínguez, José;
Lozano, Alberto Garcia;
Cabello-Gutierrez, Carlos;
Huerta, Lidia Flor Estela;
Fragoso, Gladis;
Gutiérrez-Kobeh, Laila;
Vázquez-López, Rosalino

Publication type:

Article

Role of Central Inflammatory and Oxidative Pathways in the Morphine Exacerbation of Cardiovascular Effects of Sepsis in Rats.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 882, doi. 10.3390/ph18060882

By:

Abdelnaby, Mohamed;
Sallam, Marwa Y.;
Helmy, Mai M.;
El-Gowelli, Hanan M.;
El-Mas, Mahmoud M.

Publication type:

Article

Performance of Imidazoquinoline Glycoconjugate BAIT628 as a TLR7 Agonist Prodrug for Prostate Cancer.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 804, doi. 10.3390/ph18060804

By:

Najibi, Seyedeh A.;
Pranto, S. M. Al Muied;
Haroon, Muhammad;
Nielsen, Amy E.;
Mancini, Rock J.

Publication type:

Article

Role of Extracellular Vesicles in Severe Dengue: Virus–Host Interactions and Biomarker Potential.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 807, doi. 10.3390/v17060807

By:

Agudelo, Juan Sebastian Henao;
Pereira, Gabriel;
Fernandes, Célio Junior da Costa

Publication type:

Article

Host response: New LPS receptors discovered.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 10, p. 658, doi. 10.1038/nrmicro3345

By:

Nunes-Alves, Cláudio

Publication type:

Article

Microbiome: TLR5 puts the brakes on.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 1, p. 6, doi. 10.1038/nrmicro3193

By:

Molloy, Sheilagh

Publication type:

Article

Host response: LPS goes non-canonical.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 9, p. 599, doi. 10.1038/nrmicro3106

By:

Molloy, Sheilagh

Publication type:

Article

Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 6, p. 365, doi. 10.1038/nrmicro3029

By:

Lemaitre, Bruno;
Girardin, Stephen E.

Publication type:

Article

A cure for the Flu?

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 6, p. 361, doi. 10.1038/nrmicro3039

By:

Kåhrström, Christina Tobin

Publication type:

Article

The keystone-pathogen hypothesis.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 10, p. 717, doi. 10.1038/nrmicro2873

By:

Hajishengallis, George;
Darveau, Richard P.;
Curtis, Michael A.

Publication type:

Article