Works matching DE "TIGHT junctions"

Results: 3556

The Intestinal Barrier in Parkinson's Disease: Current State of Knowledge.

Published in:

Journal of Parkinson's Disease, 2019, v. 9, p. S323, doi. 10.3233/JPD-191707

By:

van IJzendoorn, Sven C. D.;
Derkinderen, Pascal;
van Laar, Teus

Publication type:

Article

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy.

Published in:

Journal of Parkinson's Disease, 2017, v. 7, n. 2, p. 331, doi. 10.3233/JPD-160991

By:

Engen, Phillip A.;
Dodiya, Hemraj B.;
Naqib, Ankur;
Forsyth, Christopher B.;
Green, Stefan J.;
Voigt, Robin M.;
Kordower, Jeffrey H.;
Mutlu, Ece A.;
Shannon, Kathleen M.;
Keshavarzian, Ali

Publication type:

Article

Protection of LPS-induced intestinal injury in goslings by polysaccharide of Atractylodes macrocephala Koidz based on 16S rRNA and metabolomics analysis.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326164

By:

Li, Wanyan;
Lu, Baili;
Pan, Shirou;
Bai, Shuaifei;
He, Jiayu;
Li, Bingxin;
Cao, Nan;
Fu, Xinliang;
Wei, Junhao;
Chen, Ying;
Huang, Yunmao;
Tian, Yunbo;
Xu, Danning

Publication type:

Article

Comprehensive analysis reveals CLDN9 is a new biomarker in human cancers and immunotherapeutic target for glioblastoma multiforme.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03852-5

By:

Zhu, Yuanyuan;
Li, Ning;
Peng, Fang

Publication type:

Article

A method for assessment of cigarette smoke exposure toxicity based on human lung epithelial microfluidic chip.

Published in:

Tobacco Science & Technology, 2025, v. 58, n. 6, p. 9, doi. 10.16135/j.issn1002-0861.2025.0068

By:

PAN Xiaowei;
WU Junzhang;
TAO Hong;
ZOU Zhengyu;
WANG Yuting;
REN Jiexin;
CHEN Senlin

Publication type:

Article

Modulation of gut microbiota and immune response by soy peptides mitigates irinotecan induced intestinal toxicity.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1538733

By:

Jing, Yongfa;
Yan, Dongli

Publication type:

Article

The effects of rifaximin and lactulose on the gut-liver-brain axis in rats with minimal hepatic encephalopathy.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325988

By:

Lin, Xueyan;
Zhang, Zhengchao;
Lin, Yi;
Lu, Shiyun;
Chen, Rongrong

Publication type:

Article

Epigenetic silencing and CRISPR-mediated reactivation of tight junction protein claudin10b (CLDN10B) in renal cancer.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01911-2

By:

Villora, Sarah Arroyo;
Zhao, Yufen;
Silva, Paula Castellanos;
Hahn, Alba A.;
Olanin, Vivien;
Groll, David;
Maurer, Sandra;
Roetzer, Vera;
Szymanski, Witold;
Procida-Kowalski, Tara;
Philipp, Niklas;
Koch, Aline;
Bartkuhn, Marek;
Graumann, Johannes;
Volckmann, Richard;
Koster, Jan;
Rossbach, Oliver;
Salzig, Denise;
Dammann, Reinhard;
Sigges, Cornelia

Publication type:

Article

铁皮石斛多糖对小肠上皮细胞肠道屏障的保护作用.

Published in:

Modern Food Science & Technology, 2025, v. 41, n. 5, p. 28, doi. 10.13982/j.mfst.1673-9078.2025.5.0399

By:

张雅欣;
李拥军;
梁嘉熹;
刘袆帆

Publication type:

Article

CCL2 Inhibitor Bindarit Improve Postoperative Cognitive Function by Attenuating Pericyte Loss‐Related Blood–Brain Barrier Disruption and Neuroinflammation.

Published in:

Mediators of Inflammation, 2025, v. 2025, p. 1, doi. 10.1155/mi/7248780

By:

Yuan, Hui;
Lu, Bo;
Sun, Daofan;
Chen, Junping;
Fang, Xiangming;
Arora, Jasbir

Publication type:

Article

HIF-1α-Mediated Disruption of Cellular Junctions: The Impact of Hypoxia on the Tumor Microenvironment and Invasion.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5101, doi. 10.3390/ijms26115101

By:

Springer, Michael;
Burakgazi, Zeynep Aydin;
Domukhovska, Anastasiia;
Nafchi, Ben;
Beary, Michael C.;
Acquisto, Arielle;
Acquisto, Juliette;
Komarov, Vladyslav;
Jensen, Madison;
Gulledge, Brandon;
Poplavskyi, Maksym;
Uddin, Md Gias;
Rayan, Gamal;
Zucker, Shoshanna N.

Publication type:

Article

Regulation of Blood–Brain Barrier Permeability via JNK Signaling Pathway: Mechanisms and Potential Therapeutic Strategies for Ischemic Stroke, Alzheimer's Disease and Brain Tumors.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2353, doi. 10.3390/molecules30112353

By:

Plotnikov, Mark B.;
Anishchenko, Anna M.;
Khlebnikov, Andrei I.;
Schepetkin, Igor A.

Publication type:

Article

Polystyrene nanoplastics disrupt the intestinal microenvironment by altering bacteria-host interactions through extracellular vesicle-delivered microRNAs.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59884-y

By:

Hsu, Wei-Hsuan;
Chen, You-Zuo;
Chiang, Yi-Ting;
Chang, Yi-Tsen;
Wang, Yi-Wen;
Hsu, Kung-Ting;
Hsu, Yi-Yun;
Wu, Pei-Ting;
Lee, Bao-Hong

Publication type:

Article

Plasmon-activated water enhances gut-barrier function and alleviates inflammation in a mouse model of ulcerative colitis.

Published in:

Experimental & Therapeutic Medicine, 2025, v. 30, n. 1, p. N.PAG, doi. 10.3892/etm.2025.12896

By:

Chang, Chun-Chao;
Chang, Chih-Ju;
Liu, Chih-Yi;
Yeh, Hsing-Jung;
Li, Yu-Ju;
Chen, Wen-Chao;
Chang, Chun-Wei;
Pan, Jun-Liang;
Liu, Yu-Chuan;
Huang, Chi-Jung

Publication type:

Article

In vitro and in vivo effects of Centella asiatica on intestinal inflammatory models and identification of its bioactive components.

Published in:

Journal of the Science of Food & Agriculture, 2025, v. 105, n. 9, p. 4833, doi. 10.1002/jsfa.14213

By:

Shin, Hyun Young;
Kim, Yeon Suk;
Joung, Mi Yeun;
Kim, Woo Jung;
Shin, Kwang‐Soon;
Yu, Kwang‐Won

Publication type:

Article

Study on the Intestinal Epithelial Transport Characteristics and Barrier Damage Effects of Dietary ALEs.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2025, v. 25, n. 3, p. 23, doi. 10.16429/j.1009-7848.2025.03.003

By:

WANG Yaya;
L1 Yuanfei;
WANG Ruican;
WANG Shuo

Publication type:

Article

Effects of Dietary Clostridium butyricum on Growth and Intestinal Mucosal Barrier Functions of Juvenile Channel Catfish (Ictalurus punctatus).

Published in:

Microorganisms, 2025, v. 13, n. 5, p. 1061, doi. 10.3390/microorganisms13051061

By:

Guo, Zihe;
Qian, Ye;
Peng, Xiao;
Qin, Chanxia;
Ren, Huige;
Du, Jingyi;
Huang, Chengrui;
Pan, Mingzhu;
Ou, Weihao

Publication type:

Article

Evaluation of Dietary Bioactive Agents Against Aflatoxin B1 and Ochratoxin A-Induced Duodenal Toxicity in Rats.

Published in:

Foods, 2025, v. 14, n. 10, p. 1793, doi. 10.3390/foods14101793

By:

Rafai, Sarra;
Cimbalo, Alessandra;
Manyes, Lara

Publication type:

Article

Alleviating the Effect of Branched-Chain Fatty Acids on the Lipopolysaccharide-Induced Inflammatory Response in Calf Small Intestinal Epithelial Cells.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 608, doi. 10.3390/antiox14050608

By:

Zhang, Siqi;
Yu, Qingyuan;
Sun, Yukun;
Zhang, Guangning;
Zhang, Yonggen;
Xin, Hangshu

Publication type:

Article

Engeletin Targets Mitochondrial Dysfunction to Attenuate Oxidative Stress and Experimental Colitis in Intestinal Epithelial Cells Through AMPK/SIRT1/PGC-1α Signaling.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 524, doi. 10.3390/antiox14050524

By:

Li, Jing;
Geng, Zhijun;
Yin, Lixia;
Huang, Ju;
Niu, Minzhu;
Zhang, Keni;
Song, Xue;
Wang, Yueyue;
Zuo, Lugen;
Hu, Jianguo

Publication type:

Article

S100A4 participates in sepsis-induced endothelial cell inflammatory response and barrier damage by binding to BRD4.

Published in:

Clinical Hemorheology & Microcirculation, 2025, v. 89, n. 3, p. 302, doi. 10.1177/13860291251313579

By:

Chen, Xiujing;
Yang, Ping

Publication type:

Article

Tannic Acid and Ethacridine Lactate Attenuate Markers of Stress-Induced Intestinal Barrier Dysfunctions in Murine Small Intestinal Organoids.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 650, doi. 10.3390/biom15050650

By:

Filipe Rosa, Louisa;
Gonda, Steffen;
Roese, Nadine;
Bischoff, Stephan C.

Publication type:

Article

HIF-1α Enhances Intestinal Injury and Inflammation in Severe Acute Pancreatitis Through NLRP3 Inflammasome Activation.

Published in:

Digestive Diseases & Sciences, 2025, v. 70, n. 5, p. 1813, doi. 10.1007/s10620-025-08926-y

By:

Gao, Tao;
Zhang, Huaisheng;
Xu, Yuan;
He, Guosong;
Ma, Huicong;
Zheng, Chuanming;
Li, Lei;
Cheng, Feng;
Dou, Hehe;
Zhang, Fulong;
Zhao, Heng;
Qiu, Zhaolei

Publication type:

Article

Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.

Published in:

Physiological Research, 2025, v. 74, n. 2, p. 287, doi. 10.33549/physiolres.935487

By:

Ting LI;
Xiaoying WANG;
Jiawei WANG

Publication type:

Article

Macronutrients as Regulators of Intestinal Epithelial Permeability: Where Do We Stand?

Published in:

Comprehensive Reviews in Food Science & Food Safety, 2025, v. 24, n. 3, p. 1, doi. 10.1111/1541-4337.70178

By:

Martínez‐Augustin, Olga;
Tena‐Garitaonaindia, Mireia;
Ceacero‐Heras, Diego;
Jiménez‐Ortas, Ángela;
Enguix‐Huete, Juan J.;
Álvarez‐Mercado, Ana I.;
Ruiz‐Henares, Guillermo;
Aranda, Carlos J.;
Gámez‐Belmonte, Reyes;
Sánchez de Medina, Fermín

Publication type:

Article

Effect of Organic, Nano, and Inorganic Zinc Sources on Growth Performance, Antioxidant Function, and Intestinal Health of Young Broilers.

Published in:

Biological Trace Element Research, 2025, v. 203, n. 5, p. 2776, doi. 10.1007/s12011-024-04341-y

By:

Xie, Shuxian;
Li, Yipu;
Suo, Yanrui;
Wang, Zheng;
Zhang, Bo;
Li, Jing;
Huang, Jianguo;
Wang, Yalei;
Ma, Chunjian;
Lin, Dongmei;
Ma, Tenghe;
Shao, Yuxin

Publication type:

Article

The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1559812

By:

Rosenthal, Rita;
Waesch, Anne;
Masete, Kopano Valerie;
Massarani, Alain S.;
Schulzke, Jörg-Dieter;
Hering, Nina A.

Publication type:

Article

Corrigendum: MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro.

Published in:

2025

By:

Alhendi, Ala';
Naser, Saleh A.

Publication type:

Correction Notice

Cannabidiol Mitigates Deoxynivalenol-Induced Intestinal Toxicity by Regulating Inflammation, Oxidative Stress, and Barrier Integrity.

Published in:

Toxins, 2025, v. 17, n. 5, p. 241, doi. 10.3390/toxins17050241

By:

Yang, Lingchen;
Decas, Tristan;
Zhang, Yuhang;
Alassane-Kpembi, Imourana

Publication type:

Article

The role of gut leakage and immune cell miss-homing on gut dysbiosis-induced lung inflammation in a DSS mice model.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0324230

By:

Eladham, Mariam Wed;
Sharif-Askari, Narjes Saheb;
Sekar, Priyadharshini;
Mdkhana, Bushra;
Selvakumar, Balachandar;
Al-Sheakly, Baraa Khalid Salah;
Sharif-Askari, Fatemeh Saheb;
Hachim, Ibrahim;
Halwani, Rabih

Publication type:

Article

Profiling Tight Junction Protein Expression in Brain Vascular Malformations.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4558, doi. 10.3390/ijms26104558

By:

Pedrosa, Leire;
Mosteiro, Alejandra;
Reyes, Luis;
Amaro, Sergio;
Menéndez-Girón, Sebastián;
Rivera, Mateo Cortés;
Domínguez, Carlos J.;
Planas, Anna M.;
Torné, Ramon;
Rodríguez-Hernández, Ana

Publication type:

Article

Interferon regulatory factor-1–expressing astrocytes are epigenetically controlled and exacerbate TBI-associated pathology in mice.

Published in:

Science Translational Medicine, 2025, v. 17, n. 800, p. 1, doi. 10.1126/scitranslmed.adr5300

By:

Cui, Wenxing;
Bai, Hao;
Guo, Chengxuan;
Zhou, Jinpeng;
Feng, Dayun;
Zhang, Shiji;
Gao, Fei;
Han, Liying;
Tian, Yang;
Dong, Jingyu;
Wei, Feilong;
Bai, Jian;
Wu, Xun;
Shi, Yingwu;
Guo, Hao;
Wang, Liang;
Li, Zhihong;
Guo, Wei;
Zhao, Tianzhi;
Heng, Lijun

Publication type:

Article

Bacterial pathogenesis: Breaching the bloodbrain barrier.

Published in:

Nature Reviews Microbiology, 2005, v. 3, n. 10, p. 744, doi. 10.1038/nrmicro1271

By:

O'Connell, David

Publication type:

Article

Ghrelin alleviates endoplasmic reticulum stress and inflammation-mediated reproductive dysfunction induced by stress.

Published in:

Journal of Assisted Reproduction & Genetics, 2019, v. 36, n. 11, p. 2357, doi. 10.1007/s10815-019-01589-5

By:

Wang, Yueying;
Cao, Longqiao;
Liu, Xiaoran

Publication type:

Article

Comparison of tight junction protein expression in the ciliary epithelia of mouse, rabbit, cat and human eyes.

Published in:

Biotechnic & Histochemistry, 2011, v. 86, n. 3, p. 161, doi. 10.3109/10520290903504340

By:

Karim, MJ;
Biswas, S;
Bhattacherjee, P;
Paterson, CA

Publication type:

Article

Using quantum dots to visualize clathrin associations.

Published in:

Biotechnic & Histochemistry, 2009, v. 84, n. 3, p. 109, doi. 10.1080/10520290902881967

By:

Ogunkoya, Y;
Nickel, BM;
Gay, VL;
Murray, SA

Publication type:

Article

SiP Epitaxial Growth for DRAM Bit Contact.

Published in:

Journal of Electronic Materials, 2025, v. 54, n. 4, p. 2930, doi. 10.1007/s11664-025-11776-z

By:

Sahu, Protyush;
Brown, Jay;
Borsari, Silvia;
Hull, Jeff

Publication type:

Article

The Impact of Paracoccidioides spp Infection on Central Nervous System Cell Junctional Complexes.

Published in:

Mycopathologia, 2022, v. 187, n. 5/6, p. 567, doi. 10.1007/s11046-022-00653-6

By:

de Almeida, Sérgio Monteiro;
Kulik, Amanda;
Malaquias, Mineia Alessandra Scaranello;
Nagashima, Seigo;
de Paula, Caroline Busatta Vaz;
Muro, Marisol Dominguez;
de Noronha, Lucia

Publication type:

Article

Protein kinase C iota (PKCι) and pVHL are both needed for lysosomal degradation of α5 integrin in renal carcinoma cells.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10272-1

By:

Schurr, Alissa F.;
Dave, Chandni S.;
Shah, Prachi J.;
Meth, Jennifer L.;
Jaramillo, Alexandria S.;
Bartley, Kelly;
Schoenfeld, Alan R.

Publication type:

Article

GM130-silencing may aggravate blood-brain barrier damage and affect microglia polarization by down-regulating PD-L1 expression after experimental intracerebral hemorrhage.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09859-x

By:

Chen, Xiqian;
Ren, Yijun;
Xie, Pinghui;
Lei, Qiang;
Lu, Wei

Publication type:

Article

COVID-19 and the brain: understanding the pathogenesis and consequences of neurological damage.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09279-x

By:

Maliha, Sumaiya Tasnim;
Fatemi, Rabeya;
Araf, Yusha

Publication type:

Article

VLA-4 antagonists: Potent inhibitors of lymphocyte migration.

Published in:

Medicinal Research Reviews, 2003, v. 23, n. 3, p. 369, doi. 10.1002/med.10044

By:

Ginger X. Yang;
William K. Hagmann

Publication type:

Article

Morphological examination of the effects of defibrotide on experimentally induced bladder injury and its relation to interstitial cystitis.

Published in:

Urological Research, 2001, v. 29, n. 4, p. 1, doi. 10.1007/s002400100196

By:

Aydin, Hakan;
Ercan, Feriha;
Çetinel, Sule;
San, Tangül

Publication type:

Article

Effects of hyperbaric oxygen on the expression of claudins after cerebral ischemia-reperfusion in rats.

Published in:

Experimental Brain Research, 2011, v. 212, n. 1, p. 109, doi. 10.1007/s00221-011-2702-3

By:

Zhao, Hong;
Zhang, Qianru;
Xue, Yixue;
Chen, Xuexin;
Haun, Randy

Publication type:

Article

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels.

Published in:

Basic Research in Cardiology, 2013, v. 108, n. 3, p. 1, doi. 10.1007/s00395-013-0348-y

By:

Lübkemeier, Indra;
Requardt, Robert;
Lin, Xianming;
Sasse, Philipp;
Andrié, René;
Schrickel, Jan;
Chkourko, Halina;
Bukauskas, Feliksas;
Kim, Jung-Sun;
Frank, Marina;
Malan, Daniela;
Zhang, Jiong;
Wirth, Angela;
Dobrowolski, Radoslaw;
Mohler, Peter;
Offermanns, Stefan;
Fleischmann, Bernd;
Delmar, Mario;
Willecke, Klaus

Publication type:

Article

Cystine reduces tight junction permeability and intestinal inflammation induced by oxidative stress in Caco-2 cells.

Published in:

Amino Acids, 2021, v. 53, n. 7, p. 1021, doi. 10.1007/s00726-021-03001-y

By:

Hasegawa, Tatsuya;
Mizugaki, Ami;
Inoue, Yoshiko;
Kato, Hiroyuki;
Murakami, Hitoshi

Publication type:

Article

Asymmetric dimethylarginine aggravates blood–retinal barrier breakdown of diabetic retinopathy via inhibition of intercellular communication in retinal pericytes.

Published in:

Amino Acids, 2019, v. 51, n. 10-12, p. 1515, doi. 10.1007/s00726-019-02788-1

By:

Huang, Chu-Yi;
Zhou, Ting;
Li, Ge;
Li, Ming-Yuan;
Xiong, Xiao-Ming;
Wu, Mei-Ting;
Jiang, Jun-Lin

Publication type:

Article

Glycine supplementation to breast-fed piglets attenuates post-weaning jejunal epithelial apoptosis: a functional role of CHOP signaling.

Published in:

Amino Acids, 2019, v. 51, n. 3, p. 463, doi. 10.1007/s00726-018-2681-9

By:

Fan, Xiaoxiao;
Li, Shuai;
Wu, Zhenlong;
Dai, Zhaolai;
Li, Ju;
Wang, Xiaolong;
Wu, Guoyao

Publication type:

Article

Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells.

Published in:

Amino Acids, 2015, v. 47, n. 10, p. 2177, doi. 10.1007/s00726-014-1844-6

By:

Yang, Ying;
Li, Wei;
Sun, Yuli;
Han, Feng;
Hu, Chien-An;
Wu, Zhenlong

Publication type:

Article

Expression of Zonula Occludens-1 and Claudin-1 Proteins in Japanese Quails Testis.

Published in:

Veterinary Sciences & Practices, 2023, v. 18, n. 2, p. 58, doi. 10.5152/VetSciPract.2023.22070

By:

ÜNDAĞ, İlknur;
DÖNMEZ, Hasan Hüseyin

Publication type:

Article