Works matching DE "THROMBOXANE receptors"

Results: 32

Host knockout of E-prostanoid 2 receptors reduces tumor growth and causes major alterations of gene expression in prostaglandin E2-producing tumors.

Published in:

Oncology Letters, 2017, v. 13, n. 1, p. 476, doi. 10.3892/ol.2016.5448

By:

ASTING, ANNIKA GUSTAFSSON;
IRESJÖ, BRITT-MARIE;
NILSBERTH, CAMILLA;
SMEDH, ULRIKA;
LUNDHOLM, KENT

Publication type:

Article

Thromboxane A2 Receptor: Biology and Function of a Peculiar Receptor that Remains Resistant for Therapeutic Targeting.

Published in:

Journal of Cardiovascular Pharmacology & Therapeutics, 2012, v. 17, n. 3, p. 248, doi. 10.1177/1074248411424145

By:

Ting, Harold J.;
Murad, John P.;
Espinosa, Enma V. P.;
Khasawneh, Fadi T.

Publication type:

Article

Platelets in vascular disease.

Published in:

Clinical Hemorheology & Microcirculation, 2013, v. 53, n. 1-2, p. 71, doi. 10.3233/ch-2012-1577

By:

Reinhart, W.H.

Publication type:

Article

Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085937

By:

Chakraborty, Raja;
Bhullar, Rajinder P.;
Dakshinamurti, Shyamala;
Hwa, John;
Chelikani, Prashen

Publication type:

Article

High-Level Expression, Purification and Characterization of a Constitutively Active Thromboxane A2 Receptor Polymorphic Variant.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0076481

By:

Xu, Bing;
Chakraborty, Raja;
Eilers, Markus;
Dakshinamurti, Shyamala;
O’Neil, Joe D.;
Smith, Steven O.;
Bhullar, Rajinder P.;
Chelikani, Prashen

Publication type:

Article

Human Thromboxane A2 Receptor Genetic Variants: In Silico, In Vitro and “In Platelet” Analysis.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067314

By:

Gleim, Scott;
Stitham, Jeremiah;
Tang, Wai Ho;
Li, Hong;
Douville, Karen;
Chelikani, Prashen;
J.Rade, Jeffrey;
Martin, Kathleen A.;
Hwa, John

Publication type:

Article

Full and Partial Agonists of Thromboxane Prostanoid Receptor Unveil Fine Tuning of Receptor Superactive Conformation and G Protein Activation.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0060475

By:

Capra, Valérie;
Busnelli, Marta;
Perenna, Alessandro;
Ambrosio, Manuela;
Accomazzo, Maria Rosa;
Galés, Celine;
Chini, Bice;
Rovati, G. Enrico

Publication type:

Article

Attenuated Vasodilator Effectiveness of Protease-Activated Receptor 2 Agonist in Heterozygous par2 Knockout Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055965

By:

Hennessey, John C.;
McGuire, John J.

Publication type:

Article

Statins and Selective Inhibition of Rho Kinase Protect Small Conductance Calcium-Activated Potassium Channel Function (KCa2.3) in Cerebral Arteries.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046735

By:

McNeish, Alister J.;
Jimenez-Altayo, Francesc;
Cottrell, Graeme S.;
Garland, Christopher J.

Publication type:

Article

Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029996

By:

Chakraborty, Raja;
Pydi, Sai Prasad;
Gleim, Scott;
Dakshinamurti, Shyamala;
Hwa, John;
Chelikani, Prashen

Publication type:

Article

Platelets and thromboxane receptors: pivotal players in arteriogenesis.

Published in:

Cardiovascular Research, 2015, v. 107, n. 4, p. 400, doi. 10.1093/cvr/cvv194

By:

Van Hinsbergh, Victor W. M.;
Tasev, Dimitar

Publication type:

Article

TBXA2R gene variants associated with bleeding.

Published in:

Platelets, 2018, v. 29, n. 7, p. 739, doi. 10.1080/09537104.2018.1499888

By:

Mundell, Stuart James;
Mumford, Andrew

Publication type:

Article

Lead compound design for TPR/COX dual inhibition.

Published in:

Journal of Molecular Modeling, 2012, v. 18, n. 9, p. 4397, doi. 10.1007/s00894-012-1435-y

By:

Krishna, Abhay;
Yadav, Arpita

Publication type:

Article

Prostanoid Receptor Antagonist Effects on Intraocular Pressure, Supported by Ocular Biodisposition Experiments.

Published in:

2016

By:

Woodward, David F.;
Wenthur, Stacey L.;
Rudebush, Tara L.;
Shan Fan;
Toris, Carol B.;
Fan, Shan

Publication type:

journal article

Peroxynitrite formed during a transient episode of brain ischaemia increases endothelium-derived hyperpolarization-type dilations in thromboxane/prostaglandin receptor-stimulated rat cerebral arteries.

Published in:

Acta Physiologica, 2017, v. 220, n. 1, p. 150, doi. 10.1111/apha.12809

By:

Onetti, Y.;
Dantas, A. P.;
Pérez, B.;
McNeish, A. J.;
Vila, E.;
Jiménez‐Altayó, F.

Publication type:

Article

Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries.

Published in:

Acta Physiologica, 2017, v. 219, n. 1, p. 188, doi. 10.1111/apha.12642

By:

Siangjong, L.;
Goldman, D. H.;
Kriska, T.;
Gauthier, K. M.;
Smyth, E. M.;
Puli, N.;
Kumar, G.;
Falck, J. R.;
Campbell, W. B.

Publication type:

Article

Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB.

Published in:

BMC Pharmacology & Toxicology, 2014, v. 15, n. 1, p. 27, doi. 10.1186/2050-6511-15-73

By:

Touchberry, Chad D.;
Silswal, Neerupma;
Tchikrizov, Vladimir;
Elmore, Christopher J.;
Srinivas, Shubra;
Akthar, Adil S.;
Swan, Hannah K.;
Wetmore, Lori A.;
Wacker, Michael J.

Publication type:

Article

Thromboxane A2 Receptor Stimulation Enhances Microglial Interleukin-1β and NO Biosynthesis Mediated by the Activation of ERK Pathway.

Published in:

Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00008

By:

Wanlin Yang;
Aijuan Yan;
Tingting Zhang;
Jiaxiang Shao;
Tengyuan Liu;
Xiao Yang;
Weiliang Xia;
Yi Fu

Publication type:

Article

Prostaglandin E2 EP4 Receptor Activation Attenuates Neuroinflammation and Early Brain Injury Induced by Subarachnoid Hemorrhage in Rats.

Published in:

Neurochemical Research, 2017, v. 42, n. 4, p. 1267, doi. 10.1007/s11064-016-2168-6

By:

Xu, Jie;
Xu, Zhen;
Yan, Ai

Publication type:

Article

Enhanced parenchymal arteriole tone and astrocyte signaling protect neurovascular coupling mediated parenchymal arteriole vasodilation in the spontaneously hypertensive rat.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 7, p. 1127, doi. 10.1038/jcbfm.2015.31

By:

Iddings, Jennifer A;
Kim, Ki Jung;
Zhou, Yiqiang;
Higashimori, Haruki;
Filosa, Jessica A

Publication type:

Article

Activation of thromboxane A2 receptors mediates endothelial dysfunction in diabetic mice.

Published in:

Clinical & Experimental Hypertension, 2017, v. 39, n. 4, p. 312, doi. 10.1080/10641963.2016.1246558

By:

Xie, Xiaona;
Sun, Wanchun;
Wang, Jun;
Li, Xiaoou;
Liu, Xiaofeng;
Liu, Ning

Publication type:

Article

Association of thromboxane A2 receptor gene polymorphisms with cerebral infarction in a Chinese population.

Published in:

Neurological Sciences, 2013, v. 34, n. 10, p. 1791, doi. 10.1007/s10072-013-1340-x

By:

Zhao, Jing;
Zheng, Lan;
Fei, Qingzhou;
Fu, Yi;
Weng, Yingfeng;
Wu, Hui;
Li, Huanyin;
Jun, Qi;
Shao, Jingshan;
Xu, Yuming

Publication type:

Article

Antagonism of the thromboxane-prostanoid receptor is cardioprotective against right ventricular pressure overload.

Published in:

Pulmonary Circulation, 2016, v. 6, n. 2, p. 211, doi. 10.1086/686140

By:

West, James D.;
Voss, Bryan M.;
Pavliv, Leo;
de Caestecker, Mark;
Hemnes, Anna R.;
Carrier, Erica J.

Publication type:

Article

Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS‑induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF‑κB signaling pathways.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 3, p. 2491, doi. 10.3892/mmr.2017.6884

By:

AIJUAN YAN;
GAOYU CAI;
WEILIANG XIA;
YI FU

Publication type:

Article

Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke.

Published in:

Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00089

By:

DeMars, Kelly M.;
McCrea, Austin O.;
Siwarski, David M.;
Sanz, Brian D.;
Yang, Changjun;
Candelario-Jalil, Eduardo

Publication type:

Article

Revisiting the usefulness of thromboxane-A2 modulation in the treatment of bronchoconstriction in asthma1.

Published in:

Canadian Journal of Physiology & Pharmacology, 2015, v. 93, n. 2, p. 111, doi. 10.1139/cjpp-2014-0364

By:

Hernandez, Jeremy Mark;
Janssen, Luke Jeffrey

Publication type:

Article

Analysis of 65 pregnancies in 34 women with five different forms of inherited platelet function disorders.

Published in:

British Journal of Haematology, 2015, v. 170, n. 4, p. 559, doi. 10.1111/bjh.13458

By:

Civaschi, Elisa;
Klersy, Catherine;
Melazzini, Federica;
Pujol‐Moix, Nuria;
Santoro, Cristina;
Cattaneo, Marco;
Lavenu‐Bombled, Cécile;
Bury, Loredana;
Minuz, Pietro;
Nurden, Paquita;
Cid, Ana R.;
Cuker, Adam;
Latger‐Cannard, Véronique;
Favier, Remi;
Nichele, Ilaria;
Noris, Patrizia

Publication type:

Article

The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.

Published in:

Cell Biology International, 2010, v. 34, n. 9, p. 943, doi. 10.1042/CBI20090491

By:

Tatsuya Kawaguchi;
Ryuji Hashimoto;
Hiroshi Yokota

Publication type:

Article

The small GTPase Rac1 is required for smooth muscle contraction.

Published in:

Journal of Physiology, 2014, v. 592, n. 5, p. 915, doi. 10.1113/jphysiol.2013.262998

By:

Rahman, Awahan;
Davis, Benjamin;
Lövdahl, Cecilia;
Hanumaiah, Veena T.;
Feil, Robert;
Brakebusch, Cord;
Arner, Anders

Publication type:

Article

Functional variants in the thromboxane A2 receptor gene are associated with lung function in childhood-onset asthma.

Published in:

Clinical & Experimental Allergy, 2013, v. 43, n. 4, p. 413, doi. 10.1111/cea.12058

By:

Takeuchi, K.;
Mashimo, Y.;
Shimojo, N.;
Arima, T.;
Inoue, Y.;
Morita, Y.;
Sato, K.;
Suzuki, S.;
Nishimuta, T.;
Watanabe, H.;
Hoshioka, A.;
Tomiita, M.;
Yamaide, A.;
Watanabe, M.;
Okamoto, Y.;
Kohno, Y.;
Hata, A.;
Suzuki, Y.

Publication type:

Article

MAPK signaling pathway regulates cerebrovascular receptor expression in human cerebral arteries.

Published in:

BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-12

By:

Ansar, Saema;
Eftekhari, Sajedeh;
Waldsee, Roya;
Nilsson, Elisabeth;
Nilsson, Ola;
Säveland, Hans;
Edvinsson, Lars

Publication type:

Article

Oral Presentation – Asthma.

Published in:: 2014
Publication type:: Abstract

Works matching DE "THROMBOXANE receptors"

Host knockout of E-prostanoid 2 receptors reduces tumor growth and causes major alterations of gene expression in prostaglandin E<sub>2</sub>-producing tumors.

Thromboxane A2 Receptor: Biology and Function of a Peculiar Receptor that Remains Resistant for Therapeutic Targeting.

Platelets in vascular disease.

Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor.

High-Level Expression, Purification and Characterization of a Constitutively Active Thromboxane A2 Receptor Polymorphic Variant.

Human Thromboxane A<sub>2</sub> Receptor Genetic Variants: <i>In Silico</i>, <i>In Vitro</i> and “In Platelet” Analysis.

Full and Partial Agonists of Thromboxane Prostanoid Receptor Unveil Fine Tuning of Receptor Superactive Conformation and G Protein Activation.

Attenuated Vasodilator Effectiveness of Protease-Activated Receptor 2 Agonist in Heterozygous <i>par2</i> Knockout Mice.

Statins and Selective Inhibition of Rho Kinase Protect Small Conductance Calcium-Activated Potassium Channel Function (K<sub>Ca</sub>2.3) in Cerebral Arteries.

Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4.

Platelets and thromboxane receptors: pivotal players in arteriogenesis.

TBXA2R gene variants associated with bleeding.

Lead compound design for TPR/COX dual inhibition.

Prostanoid Receptor Antagonist Effects on Intraocular Pressure, Supported by Ocular Biodisposition Experiments.

Peroxynitrite formed during a transient episode of brain ischaemia increases endothelium-derived hyperpolarization-type dilations in thromboxane/prostaglandin receptor-stimulated rat cerebral arteries.

Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries.

Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB.

Thromboxane A<sub>2</sub> Receptor Stimulation Enhances Microglial Interleukin-1β and NO Biosynthesis Mediated by the Activation of ERK Pathway.

Prostaglandin E2 EP4 Receptor Activation Attenuates Neuroinflammation and Early Brain Injury Induced by Subarachnoid Hemorrhage in Rats.

Enhanced parenchymal arteriole tone and astrocyte signaling protect neurovascular coupling mediated parenchymal arteriole vasodilation in the spontaneously hypertensive rat.

Activation of thromboxane A2 receptors mediates endothelial dysfunction in diabetic mice.

Association of thromboxane A2 receptor gene polymorphisms with cerebral infarction in a Chinese population.

Antagonism of the thromboxane-prostanoid receptor is cardioprotective against right ventricular pressure overload.

Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS‑induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF‑κB signaling pathways.

Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke.

Revisiting the usefulness of thromboxane-A<sub>2</sub> modulation in the treatment of bronchoconstriction in asthma<sup>1</sup>.

Analysis of 65 pregnancies in 34 women with five different forms of inherited platelet function disorders.

The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor.

The small GTPase Rac1 is required for smooth muscle contraction.

Functional variants in the thromboxane A2 receptor gene are associated with lung function in childhood-onset asthma.

MAPK signaling pathway regulates cerebrovascular receptor expression in human cerebral arteries.

Oral Presentation – Asthma.