Works matching DE "THROMBOPOIETIN"

Results: 572

A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation.

Published in:

PLoS Biology, 2010, v. 8, n. 9, p. 1, doi. 10.1371/journal.pbio.1000476

By:

Besancenot, Rodolphe;
Chaligné, Ronan;
Tonetti, Carole;
Pasquier, Florence;
Marty, Caroline;
Lécluse, Yann;
Vainchenker, William;
Constantinescu, Stefan N.;
Giraudier, Stéphane

Publication type:

Article

Thrombocytopenia in chronic liver disease.

Published in:

Liver International, 2017, v. 37, n. 6, p. 778, doi. 10.1111/liv.13317

By:

Peck ‐ Radosavljevic, Markus

Publication type:

Article

Abnormal platelet kinetics are detected before the occurrence of thrombocytopaenia in HBV-related liver disease.

Published in:

Liver International, 2014, v. 34, n. 4, p. 535, doi. 10.1111/liv.12309

By:

Wang, Xiaoyun;
Jiang, Wei;
Li, Feng;
Hua, Fanli;
Zhan, Yanxia;
Li, Yingying;
Ji, Lili;
Zou, Shanhua;
Min, Zhihui;
Song, Dongli;
Cheng, Yunfeng

Publication type:

Article

Improving pharmacological activities of thrombopoietin mimetic peptide by genetic fusion to albumin-binding domain.

Published in:

Biotechnology Letters, 2023, v. 45, n. 4, p. 439, doi. 10.1007/s10529-023-03345-3

By:

Li, Dezhou;
Gao, Guosheng;
Zhu, Bo;
Ying, Jingjing

Publication type:

Article

Successful platelet count recovery in lupus-associated thrombocytopenia with the thrombopoietin agonist eltrombopag.

Published in:

2014

By:

Scheinberg, Phillip;
Singulane, Cristiane;
Barbosa, Luis;
Scheinberg, Morton

Publication type:

Case Study

Effect of doxycycline-regulated calnexin and calreticulin expression on specific thrombopoietin productivity of recombinant chinese hamster ovary cells.

Published in:

Biotechnology & Bioengineering, 2004, v. 85, n. 5, p. 539, doi. 10.1002/bit.10919

By:

Joo Young Chung;
Seung Wook Lim;
Yeon Joo Hong;
Sun Ok Hwang;
Gyun Min Lee

Publication type:

Article

Effect of thrombopoietin on platelet counts and liver regeneration after partial hepatectomy in a rat model.

Published in:

Surgery Today, 2009, v. 39, n. 12, p. 1054, doi. 10.1007/s00595-008-4054-6

By:

Rinshun Shimabukuro;
Hirofumi Kawanaka;
Morimasa Tomikawa;
Tomohiko Akahoshi;
Kozo Konishi;
Daisuke Yoshida;
Go Anegawa;
Hideo Uehara;
Naotaka Hashimoto;
Makoto Hashizume;
Yoshihiko Maehara

Publication type:

Article

Expression and bioactivity of recombinant human serum albumin and dTMP fusion proteins in CHO cells.

Published in:

Applied Microbiology & Biotechnology, 2016, v. 100, n. 17, p. 7565, doi. 10.1007/s00253-016-7447-2

By:

Ru, Yi;
Zhi, Dejuan;
Guo, Dingding;
Wang, Yong;
Li, Yang;
Wang, Meizhu;
Wei, Suzhen;
Wang, Haiqing;
Wang, Na;
Che, Jingmin;
Li, Hongyu

Publication type:

Article

Expression, refolding, and characterization of recombinant thrombopoietin/stem cell factor fusion protein in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 74, n. 4, p. 836, doi. 10.1007/s00253-006-0734-6

By:

Yuhui Zang;
Xu Zhang;
Xiaoling Jiang;
Haoran Li;
Jie Zhu;
Chi Zhang;
Wei Peng;
Junchuan Qin

Publication type:

Article

Down-regulation of lactate dehydrogenase-A by siRNAs for reduced lactic acid formation of Chinese hamster ovary cells producing thrombopoietin.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 74, n. 1, p. 152, doi. 10.1007/s00253-006-0654-5

By:

Sung Hyun Kim;
Gyun Min Lee

Publication type:

Article

Yeast hydrolysate as a low-cost additive to serum-free medium for the production of human thrombopoietin in suspension cultures of Chinese hamster ovary cells.

Published in:

Applied Microbiology & Biotechnology, 2004, v. 63, n. 5, p. 527, doi. 10.1007/s00253-003-1389-1

By:

Sung, Y. H.;
Lim, S. W.;
Chung, J. Y.;
Lee, G. M.

Publication type:

Article

Recombinant Thrombopoietin Effectively Shortens the Time to Response and Increases Platelet Counts in Elderly Patients with Severe Immune Thrombocytopenia.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 19, p. 5763, doi. 10.3390/jcm11195763

By:

Li, Yang;
Sun, Lihua;
Li, Feng;
Li, Ying;
Hou, Yunhua;
Meng, Yahong;
Fan, Xiaohong;
Cheng, Yunfeng;
Hua, Fanli

Publication type:

Article

Eltrombopag (75 mg) does not induce photosensitivity: results of a clinical pharmacology trial.

Published in:

Photodermatology, Photoimmunology & Photomedicine, 2010, v. 26, n. 5, p. 243, doi. 10.1111/j.1600-0781.2010.00538.x

By:

Bowen, Carolyn J.;
Lobb, Kathryn M.;
Jung Wook Park;
Sanderson, Brian;
Ferguson, James

Publication type:

Article

ROMIPLOSTIM AND ELTROMBOPAG FOR IMMUNE THROMBOCYTOPENIA: METHODS FOR INDIRECT COMPARISON.

Published in:

International Journal of Technology Assessment in Health Care, 2012, v. 28, n. 3, p. 249, doi. 10.1017/S0266462312000414

By:

Cooper, Katy L.;
Fitzgerald, Patrick;
Dillingham, Kerry;
Helme, Kawitha;
Akehurst, Ron

Publication type:

Article

Corrigendum: D-dencichine regulates thrombopoiesis by promoting megakaryocyte adhesion, migration and proplatelet formation.

Published in:

2025

By:

Ding, Shilan;
Wang, Min;
Fang, Song;
Xu, Huibo;
Fan, Huiting;
Tian, Yu;
Zhai, Yadong;
Lu, Shan;
Qi, Xin;
Wei, Fei;
Sun, Guibo;
Sun, Xiaobo

Publication type:

Correction Notice

D-dencichine Regulates Thrombopoiesis by Promoting Megakaryocyte Adhesion, Migration and Proplatelet Formation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2018.00297

By:

Ding, Shilan;
Wang, Min;
Fang, Song;
Xu, Huibo;
Fan, Huiting;
Tian, Yu;
Zhai, Yadong;
Lu, Shan;
Qi, Xin;
Wei, Fei;
Sun, Guibo;
Sun, Xiaobo

Publication type:

Article

D-dencichine Regulates Thrombopoiesis by Promoting Megakaryocyte Adhesion, Migration and Proplatelet Formation.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00297

By:

Ding, Shilan;
Wang, Min;
Fang, Song;
Xu, Huibo;
Fan, Huiting;
Tian, Yu;
Zhai, Yadong;
Lu, Shan;
Qi, Xin;
Wei, Fei;
Sun, Guibo;
Sun, Xiaobo

Publication type:

Article

Romiplostim as a treatment for immune thrombocytopenia: a review.

Published in:

Journal of Blood Medicine, 2015, v. 6, p. 37, doi. 10.2147/JBM.S47240

By:

Chalmers, Sarah;
Tarantino, Michael D.

Publication type:

Article

Thrombopoietin accumulation in hepatocytes induces a decrease in its serum levels in a sinusoidal obstruction syndrome model.

Published in:

Molecular Medicine Reports, 2022, v. 25, n. 6, p. N.PAG

By:

Yamazaki, Hiroto;
Tajima, Hidehiro;
Yamamoto, Yasuhiko;
Munesue, Seiichi;
Okazaki, Mitsuyoshi;
Ohbatake, Yoshinao;
Nakanuma, Shinichi;
Makino, Isamu;
Miyashita, Tomoharu;
Takamura, Hiroyuki;
Ohta, Tetsuo

Publication type:

Article

Platelets are associated with xenograft tumor growth and the clinical malignancy of ovarian cancer through an angiogenesis-dependent mechanism.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 4, p. 2449, doi. 10.3892/mmr.2014.3082

By:

LEI YUAN;
XISHI LIU

Publication type:

Article

AKR-501 (YM477) a novel orally-active thrombopoietin receptor agonist.

Published in:

European Journal of Haematology, 2009, v. 82, n. 4, p. 247, doi. 10.1111/j.1600-0609.2008.01198.x

By:

Fukushima-Shintani, Mari;
Suzuki, Ken-ichi;
Iwatsuki, Yoshiyuki;
Abe, Masaki;
Sugasawa, Keizo;
Hirayama, Fukushi;
Kawasaki, Tomihisa;
Nakahata, Tatsutoshi

Publication type:

Article

Introduction.

Published in:

European Journal of Haematology, 2009, v. 82, p. 1, doi. 10.1111/j.1600-0609.2008.01205.x

By:

Rodeghiero, Francesco

Publication type:

Article

Romiplostim: a breakthrough treatment for the management of immune thrombocytopenic purpura.

Published in:

European Journal of Haematology, 2009, v. 82, p. 20, doi. 10.1111/j.1600-0609.2008.01209.x

By:

Newland, Adrian

Publication type:

Article

Study of gene expression profile during cord blood-associated megakaryopoiesis.

Published in:

European Journal of Haematology, 2008, v. 81, n. 3, p. 196, doi. 10.1111/j.1600-0609.2008.01104.x

By:

Che Kang Lim;
Hwang, William Y. K.;
Swee Eng Aw;
Li Sun

Publication type:

Article

New drugs for familiar therapeutic targets: thrombopoietin receptor agonists and immune thrombocytopenic purpura.

Published in:

European Journal of Haematology, 2008, v. 80, p. 9, doi. 10.1111/j.1600-0609.2007.00999.x

By:

Kuter, David J.

Publication type:

Article

Efficient assay for evaluating human thrombopoiesis using NOD/SCID mice transplanted with cord blood CD34<sup>+</sup> cells.

Published in:

European Journal of Haematology, 2007, v. 78, n. 2, p. 123, doi. 10.1111/j.1600-0609.2006.00783.x

By:

Suzuki, Ken-ichi;
Hiramatsu, Hidefumi;
Fukushima-Shintani, Mari;
Heike, Toshio;
Nakahata, Tatsutoshi

Publication type:

Article

Differentiation of hematopoietic progenitor cells towards the myeloid and B-lymphoid lineage by hepatocyte growth factor (HGF) and thrombopoietin (TPO) together with early acting cytokines.

Published in:

European Journal of Haematology, 2006, v. 77, n. 2, p. 134, doi. 10.1111/j.1600-0609.2006.00673.x

By:

Grassinger, Jochen;
Mueller, Gunnar;
Zaiss, Matthias;
Kunz-Schughart, Leoni A.;
Andreesen, Reinhard;
Hennemann, Burkhard

Publication type:

Article

CD226 is expressed on the megakaryocytic lineage from hematopoietic stem cells/progenitor cells and involved in its polyploidization.

Published in:

European Journal of Haematology, 2005, v. 74, n. 3, p. 228, doi. 10.1111/j.1600-0609.2004.00345.x

By:

Dongchu Ma;
Yinghui Sun;
Di Lin;
Haoyang Wang;
Bing Dai;
Xinghai Zhang;
Weiming Ouyang;
Jinlong Jian;
Wei Jia;
Xiaoguang Xu;
Boquan Jin

Publication type:

Article

Pharmacokinetics of pegylated recombinant human megakaryocyte growth and development factor in healthy volunteers and patients with hematological disorders.

Published in:

European Journal of Haematology, 2004, v. 73, n. 4, p. 269, doi. 10.1111/j.1600-0609.2004.00288.x

By:

Tanaka, Hideji;
Takama, Hirotaka;
Vasumasa Arai;
Junichi Azuma;
Ohno, Ryuzo;
Vasuo Ikeda;
Hideaki Mizoguchi

Publication type:

Article

Chronic thrombocytopenia of childhood: use of non-invasive methods in clinical evaluation.

Published in:

European Journal of Haematology, 2004, v. 72, n. 4, p. 268, doi. 10.1111/j.1600-0609.2004.00215.x

By:

Rajantie, J.;
Javela, K.;
Joutsi-Korhonen, L.;
Kekomaki, R.

Publication type:

Article

Simultaneous measurement of serum thrombopoietin and expression of megakaryocyte c-Mpl with clinical and laboratory correlates for myelofibrosis with myeloid metaplasia.

Published in:

European Journal of Haematology, 2002, v. 68, n. 3, p. 175, doi. 10.1034/j.1600-0609.2002.01534.x

By:

Elliott, Michelle A;
Yoon, Soo-Young;
Kao, Pai;
Li, Chin-Yang;
Tefferi, Ayalew

Publication type:

Article

Plasma thrombopoietin levels in Sebastian platelet syndrome.

Published in:

European Journal of Haematology, 2001, v. 67, n. 4, p. 265, doi. 10.1034/j.1600-0609.2001.00545.x

By:

Inaba, Tohru;
Shimazaki, Chihiro;
Nakano, Sonoko;
Fuchida, Shinichi;
Ochiai, Naoya;
Okano, Akira;
Hatsuse, Mayumi;
Ashihara, Eishi;
Fujita, Naohisa;
Nakagawa, Masao

Publication type:

Article

Lack of pathogenic mutations in the 5′-untranslated region of the thrombopoietin gene in patients with non-familial essential thrombocythaemia.

Published in:

European Journal of Haematology, 2001, v. 67, n. 4, p. 232, doi. 10.1034/j.1600-0609.2001.00550.x

By:

Allen, Anthony J. R;
Gale, Rosemary E;
Harrison, Claire N;
Machin, Samuel J;
Linch, David C

Publication type:

Article

In multiple myeloma increased thrombopoietin (Tpo) production may be involved in the maintenance of platelet production.

Published in:

European Journal of Haematology, 2001, v. 66, n. 5, p. 337, doi. 10.1034/j.1600-0609.2001.066005337.x

By:

Folman, C. C.;
de Jong, C. M.;
de Haas, M.;
von dem Borne, A. E. G. KR.

Publication type:

Article

Megakaryocyte c‐Mpl expression inchronic myeloproliferative disorders and the myelodysplastic syndrome: immunoperoxidase staining patterns and clinical correlates.

Published in:

European Journal of Haematology, 2000, v. 65, n. 3, p. 170, doi. 10.1034/j.1600-0609.2000.90235.x

By:

Yoon, Soo‐Young;
Li, Chin‐Yang;
Tefferi, Ayalew

Publication type:

Article

Indirect study of thrombopoiesis(TPO, reticulated platelets, glycocalicin)in patients with hereditary macrothrombocytopenia.

Published in:

European Journal of Haematology, 2000, v. 64, n. 3, p. 151, doi. 10.1034/j.1600-0609.2000.90072.x

By:

Fabris, F.;
Cordiano, I.;
Steffana, A.;
Ramon, R.;
Scandellari, R.;
Nichol, J. L.;
Girolami, A.

Publication type:

Article

CD[sub34][sup+] cells derived from fetal liver contained a high proportion of immature megakaryocytic progenitor cells.

Published in:

European Journal of Haematology, 2000, v. 64, n. 5, p. 304, doi. 10.1034/j.1600-0609.2000.90038.x

By:

Dong-Chu Ma;
Ying-Hui Sun;
Wei Zuo;
Kui-Zhong Chang;
Jun-Jie Chu;
Ya-Ge Liu

Publication type:

Article

Thrombopoietin activates the growth of megakaryoblasts in patients with chronic myeloproliferative disorders and myelodysplastic syndrome.

Published in:

European Journal of Haematology, 2000, v. 64, n. 4, p. 225, doi. 10.1034/j.1600-0609.2000.90001.x

By:

Hashimoto, Shigeo;
Toba, Ken;
Fuse, Ichiro;
Watanabe, Kenichi;
Takahashi, Hidenobu;
Abe, Takashi;
Yano, Toshio;
Koike, Tadashi;
Takahasi, Masuhiro;
Aizawa, Yosifusa

Publication type:

Article

Low platelet count and elevated serum thrombopoietin after severe trauma.

Published in:

European Journal of Haematology, 2000, v. 64, n. 3, p. 157, doi. 10.1034/j.1600-0609.2000.90102.x

By:

Hobisch‐Hagen, Petra;
Jelkmann, Wolfgang;
Mayr, Andreas;
Wiedermann, Franz;
Fries, Dietmar;
Herold, Manfred;
Klingler, Anton;
Schobersberger, Wolfgang

Publication type:

Article

A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic syndrome receiving lenalidomide.

Published in:

Journal of Hematology & Oncology, 2012, v. 5, n. 1, p. 71, doi. 10.1186/1756-8722-5-71

By:

Wang, Eunice S.;
Lyons, Roger M.;
Larson, Richard A.;
Gandhi, Sunil;
Delong Liu;
Matei, Carmen;
Scott, Bart;
Kuolung Hu;
Yang, Allen S.

Publication type:

Article

Systematic literature review and meta-analysis on use of Thrombopoietic agents for chemotherapy-induced thrombocytopenia.

Published in:

PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0257673

By:

Soff, Gerald A.;
Ray-Coquard, Isabelle;
Rivera, Luis J. Marfil;
Fryzek, Jon;
Mullins, Megan;
Bylsma, Lauren C.;
Park, Joseph K.

Publication type:

Article

Thrombopoietin Signaling Pathway Regulates Hepatocyte Activation in Rat Liver Regeneration.

Published in:

Biochemical Genetics, 2015, v. 53, n. 9/10, p. 244, doi. 10.1007/s10528-015-9685-x

By:

Chang, Cuifang;
Yang, Jing;
Li, Xiaofang;
Zhao, Weiming;
Li, Yu;
Guo, Pengjuan;
Wang, Gaiping;
Xu, Cunshuan

Publication type:

Article

Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study.

Published in:

Platelets, 2023, v. 34, n. 1, p. 1, doi. 10.1080/09537104.2022.2157806

By:

Xiaofan Liu;
Yusheng Bai;
Tao Wang;
Yanping Song;
Feng Sun;
Ruixiang Xia;
Feiyue Zhu;
Jun Ma;
Quanyi Lu;
Xu Ye;
Xinrong Zhan;
Linjie Li;
Xinhong Guo;
Shuqin Cheng;
Yan Li;
Zhiqiang Guo;
Youhua Chen;
Shenxian Qian;
Ling Qin;
Qing Zhang

Publication type:

Article

Efficacy and safety of high dose recombinant human thrombopoietin in the treatment of immune thrombocytopenia.

Published in:

Platelets, 2023, v. 34, n. 1, p. 1, doi. 10.1080/09537104.2023.2271568

By:

Xiuli Wang;
Hui Bi;
Lin Liu;
Yuebo Liu;
Liefen Yin;
Jin Yao;
Jingxing Yu;
Wei Tao;
Yueping Wei;
Yu Li;
Lingmei Yin;
Hongli Mu;
Yadong Du;
Zeping Zhou

Publication type:

Article

Efficacy and safety of high dose recombinant human thrombopoietin in the treatment of immune thrombocytopenia.

Published in:

Platelets, 2023, v. 34, n. 1, p. 1, doi. 10.1080/09537104.2023.2271568

By:

Wang, Xiuli;
Bi, Hui;
Liu, Lin;
Liu, Yuebo;
Yin, Liefen;
Yao, Jin;
Yu, Jingxing;
Tao, Wei;
Wei, Yueping;
Li, Yu;
Yin, Lingmei;
Mu, Hongli;
Du, Yadong;
Zhou, Zeping

Publication type:

Article

Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study.

Published in:

Platelets, 2023, v. 34, n. 1, p. 1, doi. 10.1080/09537104.2022.2157806

By:

Liu, Xiaofan;
Bai, Yusheng;
Wang, Tao;
Song, Yanping;
Sun, Feng;
Xia, Ruixiang;
Zhu, Feiyue;
Ma, Jun;
Lu, Quanyi;
Ye, Xu;
Zhan, Xinrong;
Li, Linjie;
Guo, Xinhong;
Cheng, Shuqin;
Li, Yan;
Guo, Zhiqiang;
Chen, Youhua;
Qian, Shenxian;
Qin, Ling;
Zhang, Qing

Publication type:

Article

Safety, tolerance, pharmacokinetic and pharmacodynamic properties of thrombopoietin mimetic peptide for injection in Chinese healthy volunteers: a randomized, placebo-controlled, double-blind study.

Published in:

Platelets, 2022, v. 33, n. 8, p. 1185, doi. 10.1080/09537104.2022.2073344

By:

Sheng, Xiao-Yan;
Liu, Zhi-Yan;
Zhao, Jing;
Song, Lei;
Zhao, Wen-Ming;
Zhao, Xia;
Cui, Yi-Min

Publication type:

Article

Successful treatment of acquired amegakaryocytic thrombocytopenia with eltrombopag and immunosuppressant.

Published in:

2022

By:

Tian, Hong;
Kong, Danqing;
Li, Yun;
Gu, Chengyuan;
Yu, Ziqiang;
Wang, Zhaoyue;
Wu, Depei;
Yin, Jie

Publication type:

Case Study

The thrombopoietin receptor: revisiting the master regulator of platelet production.

Published in:

Platelets, 2021, v. 32, n. 6, p. 770, doi. 10.1080/09537104.2021.1925102

By:

Hitchcock, Ian S.;
Hafer, Maximillian;
Sangkhae, Veena;
Tucker, Julie A.

Publication type:

Article

Plasma thrombopoietin levels as additional tool in clinical management of thrombocytopenic neonates.

Published in:

Platelets, 2020, v. 31, n. 1, p. 62, doi. 10.1080/09537104.2019.1572877

By:

Porcelijn, Leendert;
Huiskes, Elly;
Onderwater-Van Den Hoogen, Laura;
Folman, Claudia C;
Zwaginga, Jaap Jan;
De Haas, Masja

Publication type:

Article