Works matching DE "THROMBOMODULIN"

Results: 510

Clinical impact of recombinant thrombomodulin administration on disseminated intravascular coagulation due to severe acute pancreatitis (Recover-AP study).

Published in:

2025

By:

Ogura, Takeshi;
Ueno, Saori;
Hakoda, Akitoshi;
Okuda, Atsushi;
Nishioka, Nobu;
Sakamoto, Jun;
Matsuno, Jun;
Uba, Yuki;
Tomita, Mitsuki;
Hattori, Nobuhiro;
Nakamura, Junichi;
Bessho, Kimi;
Iwatsubo, Taro;
Aboelezz, Ahmad F.;
Nishikawa, Hiroki

Publication type:

Case Study

Drotrecogin alfa: A role in emergency department treatment of severe sepsis?

Published in:

2004

By:

McLeay, Adam M.

Publication type:

Other

Resistance to thrombomodulin is associated with de novo portal vein thrombosis and low survival in patients with cirrhosis.

Published in:

Liver International, 2016, v. 36, n. 9, p. 1322, doi. 10.1111/liv.13087

By:

La Mura, Vincenzo;
Tripodi, Armando;
Tosetti, Giulia;
Cavallaro, Flaminia;
Chantarangkul, Veena;
Colombo, Massimo;
Primignani, Massimo

Publication type:

Article

Evidence of rebalanced coagulation in acute liver injury and acute liver failure as measured by thrombin generation.

Published in:

Liver International, 2014, v. 34, n. 5, p. 672, doi. 10.1111/liv.12369

By:

Habib, Mohamed;
Roberts, Lara N.;
Patel, Raj K.;
Wendon, Julia;
Bernal, William;
Arya, Roopen

Publication type:

Article

Hyaluronic acid and endothelial damage due to paracetamol-induced hepatotoxicity.

Published in:

Liver International, 2003, v. 23, n. 2, p. 110, doi. 10.1034/j.1600-0676.2003.00808.x

By:

Williams, Anna M.;
Langley, Peter G.;
Osei-Hwediah, Johnson;
Wendon, Julia A.;
Hughes, Robin D.

Publication type:

Article

Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00548-8

By:

Patel, Maitray A.;
Knauer, Michael J.;
Nicholson, Michael;
Daley, Mark;
Van Nynatten, Logan R.;
Martin, Claudio;
Patterson, Eric K.;
Cepinskas, Gediminas;
Seney, Shannon L.;
Dobretzberger, Verena;
Miholits, Markus;
Webb, Brian;
Fraser, Douglas D.

Publication type:

Article

RETRACTED ARTICLE: Evaluation of renal vascular lesions using thrombomodulin and vascular cell adhesion molecule-1 in patients with biopsy-proven lupus nephritis.

Published in:

2023

By:

Yao, Genhong;
Zhang, Guodong;
Ling, Lijun

Publication type:

Correction Notice

Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud’s phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway.

Published in:

Clinical Rheumatology, 2018, v. 37, n. 3, p. 749, doi. 10.1007/s10067-017-3845-9

By:

Shen, Chieh-Yu;
Li, Ko-Jen;
Lai, Pei-Hsuan;
Yu, Chia-Li;
Hsieh, Song-Chou

Publication type:

Article

Recombinant human soluble thrombomodulin reduces the severity and incidence of necrotizing enterocolitis in a newborn rat model.

Published in:

Surgery Today, 2019, v. 49, n. 11, p. 971, doi. 10.1007/s00595-019-01832-7

By:

Li, Bo;
Saka, Ryuta;
Takama, Yuichi;
Ueno, Takehisa;
Tazuke, Yuko;
Okuyama, Hiroomi

Publication type:

Article

Evaluation of Plasma Thrombomodulin in Patients with Coronary Slow Flow.

Published in:

Cardiology, 2017, v. 138, n. 3, p. 141, doi. 10.1159/000460239

By:

Wang, Yong;
Jia, Peng-yu;
Chen, Bao-jun;
Chen, Yan;
Yu, Hang;
Yu, Yao;
Yang, Hui-min;
Jia, Da-lin;
Ma, Chun-yan

Publication type:

Article

Effectiveness of Soluble Recombinant Human Thrombomodulin in Patients with Severe Acute Pancreatitis Complicated by Disseminated Intravascular Coagulation.

Published in:

Turkish Journal of Anaesthesiology & Reanimation, 2019, v. 47, n. 4, p. 320, doi. 10.5152/TJAR.2019.42709

By:

Takeshi Yano;
Masahiko Taniguchi;
Tetsuro Shirasaka;
Isao Tsuneyoshi

Publication type:

Article

Elevated serum levels of macrophage migration inhibitory factor and their significant correlation with rheumatoid vasculitis disease activity.

Published in:

Modern Rheumatology, 2012, v. 22, n. 1, p. 59, doi. 10.3109/s10165-011-0466-z

By:

Wakabayashi, Kuninobu;
Otsuka, Kumiko;
Sato, Michihito;
Takahashi, Ryo;
Odai, Tsuyoshi;
Isozaki, Takeo;
Yajima, Nobuyuki;
Miwa, Yusuke;
Kasama, Tsuyoshi

Publication type:

Article

Thrombomodulin reduces α-synuclein generation and ameliorates neuropathology in a mouse model of Parkinson's disease.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01939-y

By:

Niu, Xiao-yun;
Xie, Xi-xiu;
Tuo, Hou-zhen;
Lv, Cui-ping;
Huang, Ya-ru;
Zhu, Jie;
Liang, Shi-yu;
Du, Xiao-yu;
Yang, Cheng-gang;
Hou, Sheng-jie;
Sun, Xiao-ying;
Li, Ling-jie;
Cui, Fang;
Huang, Qi-xin;
Jia, Ying-bo;
Wang, Yu-jiong;
Liu, Rui-tian

Publication type:

Article

Serum Calcification Propensity T50 Is Associated with Soluble Thrombomodulin in Patients on Hemodialysis.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 12, p. 3491, doi. 10.3390/jcm13123491

By:

Tadokoro, Takeshi;
Kato, Akihiko;
Ohmori, Hiromitsu;
Matsumoto, Tomio;
Kuro-O, Makoto;
Kobayashi, Tsuyoshi;
Ohdan, Hideki

Publication type:

Article

Expression of Pinopodes in the Endometrium from Recurrent Pregnancy Loss Women. Role of Thrombomodulin and Ezrin.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 8, p. 2634, doi. 10.3390/jcm9082634

By:

D'Ippolito, Silvia;
Di Nicuolo, Fiorella;
Papi, Massimiliano;
Castellani, Roberta;
Palmieri, Valentina;
Masciullo, Valeria;
Arena, Vincenzo;
Tersigni, Chiara;
Bernabei, Micaela;
Pontecorvi, Alfredo;
Scambia, Giovanni;
Di Simone, Nicoletta

Publication type:

Article

Human Soluble Recombinant Thrombomodulin, ART-123, Resolved Early Phase Coagulopathies, but Did Not Significantly Alter the 28 Day Outcome in the Treatment of DIC Associated with Infectious Systemic Inflammatory Response Syndromes.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1553, doi. 10.3390/jcm8101553

By:

Mori, Shusuke;
Ai, Tomohiko;
Sera, Toshiki;
Ochiai, Kanae;
Otomo, Yasuhiro

Publication type:

Article

Advance in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 728, doi. 10.3390/jcm8050728

By:

Iba, Toshiaki;
Levy, Jerrold H.;
Raj, Aditya;
Warkentin, Theodore E.

Publication type:

Article

Population pharmacokinetic analysis of thrombomodulin alfa to support dosing rationale in patients with renal impairment.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 3, p. 210, doi. 10.1002/cpdd.163

By:

Mouksassi, Mohamad-Samer;
Marier, Jean-Francois;
Bax, Leon;
Osawa, Yutaka;
Tsuruta, Kazuhisa

Publication type:

Article

Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats.

Published in:

Annals of Intensive Care, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13613-017-0340-z

By:

Helms, Julie;
Clere-Jehl, Raphaël;
Bianchini, Elsa;
Borgne, Pierrick;
Burban, Mélanie;
Zobairi, Fatiha;
Diehl, Jean-Luc;
Grunebaum, Lelia;
Toti, Florence;
Meziani, Ferhat;
Borgel, Delphine

Publication type:

Article

Effects of combination therapy using antithrombin and thrombomodulin for sepsis-associated disseminated intravascular coagulation.

Published in:

Annals of Intensive Care, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13613-017-0332-z

By:

Iba, Toshiaki;
Hagiwara, Akiyoshi;
Saitoh, Daizoh;
Anan, Hideaki;
Ueki, Yutaka;
Sato, Koichi;
Gando, Satoshi

Publication type:

Article

Plasma and hepatic tissue levels of thrombomodulin, tissue factor, NFκB and nitric oxide in responders and nonresponders to IFNα therapy.

Published in:

Journal of Viral Hepatitis, 2003, v. 10, n. 5, p. 360, doi. 10.1046/j.1365-2893.2003.00431.x

By:

George, M.;
Baluch, M.;
Van Thiel, D. H.

Publication type:

Article

Recombinant human thrombomodulin for pneumonia-induced severe ARDS complicated by DIC in children: a preliminary study.

Published in:

Journal of Anesthesia, 2021, v. 35, n. 5, p. 638, doi. 10.1007/s00540-021-02971-3

By:

Hirata, Naoyuki;
Ngo, Dong Tien;
Phan, Phuc Huu;
Ainai, Akira;
Phung, Thuy Thi Bich;
Ta, Tuan Anh;
Takasaki, Jin;
Kawachi, Shoji;
Nunoi, Hiroyuki;
Nakajima, Noriko;
Dien, Tran Minh

Publication type:

Article

Effect of thrombomodulin on the development of monocrotaline-induced pulmonary hypertension.

Published in:

Journal of Anesthesia, 2014, v. 28, n. 1, p. 26, doi. 10.1007/s00540-013-1663-z

By:

Yamada, Yasuharu;
Maruyama, Junko;
Zhang, Erquan;
Okada, Amphone;
Yokochi, Ayumu;
Sawada, Hirofumi;
Mitani, Yoshihide;
Hayashi, Tatsuya;
Suzuki, Koji;
Maruyama, Kazuo

Publication type:

Article

Prognostic Significance of Thrombomodulin mRNA in High‐Grade Soft Tissue Sarcomas after 10 years.

Published in:

Orthopaedic Surgery, 2020, v. 12, n. 6, p. 1726, doi. 10.1111/os.12779

By:

Asanuma, Kunihiro;
Nakamura, Tomoki;
Asanuma, Yumiko;
Okamoto, Takayuki;
Kakimoto, Takuya;
Yada, Yuki;
Hagi, Tomohito;
Kita, Kouji;
Nakamura, Koichi;
Matsumine, Akihiko;
Sudo, Akihiro

Publication type:

Article

Effect of cigarette smoke extract and nicotine on the expression of thrombomodulin and endothelial protein C receptor in cultured human umbilical vein endothelial cells.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1724, doi. 10.3892/mmr.2017.8070

By:

Wei, Yujie;
Lai, Bin;
Liu, Huiliang;
Li, Yi;
Zhen, Wang;
Fu, Ling

Publication type:

Article

Recombinant human soluble thrombomodulin protects against brain injury in a CVST rat model, via downregulation of the HMGB1-RAGE axis.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 6, p. 5217, doi. 10.3892/mmr.2016.5891

By:

JIAN-JUN GU;
JIE-BIN CHEN;
JIAN-HE ZHANG;
HAO ZHANG;
SHOU-SEN WANG

Publication type:

Article

LXR agonist T0901317 upregulates thrombomodulin expression in glomerular endothelial cells by inhibition of nuclear factor-κB.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 6, p. 4888, doi. 10.3892/mmr.2016.5138

By:

HANLU DING;
YI LI;
YUNLIN FENG;
JIN CHEN;
XIANG ZHONG;
NAN WANG;
WEI WANG;
PING ZHANG;
LI WANG

Publication type:

Article

Plasma thrombomodulin levels are associated with acute kidney injury in patients with acute heart failure.

Published in:

Annals of Medicine, 2022, v. 54, n. 1, p. 3168, doi. 10.1080/07853890.2022.2142660

By:

Lin, Shu-Min;
Chang, Chih-Hsiang;
Lin, Ting-Yu;
Huang, Allen Chung-Cheng;
Lin, Chiung-Hung;
Chen, Yung-Chang;
Chu, Pao-Hsien

Publication type:

Article

Angiosarcoma of the tongue: report of a case with immunohistochemical findings.

Published in:

1999

By:

Tabata, Masashi;
Sugihara, Kazumasa;
Matsul, Ryutaro;
Yonezawa, Suguru;
Abeyama, Kazuhiro;
Maruyama, Ikuro;
Tabata, M;
Sugihara, K;
Matsui, R;
Yonezawa, S;
Abeyama, K;
Maruyama, I

Publication type:

journal article

An immunohistochemical study of thrombomodulin in oral squamous cell carcinoma and its association with invasive and metastatic potential.

Published in:

1997

By:

Tabata, Masashi;
Sugihara, Kazumasa;
Yonezawa, Suguru;
Yamashita, Sukehide;
Maruyama, Luro;
Tabata, M;
Sugihara, K;
Yonezawa, S;
Yamashita, S;
Maruyama, I

Publication type:

journal article

The use of thrombomodulin to study epithelial cell differentiation in neoplastic and non-neoplastic oral lesions.

Published in:

1995

By:

Tabata, Masashi;
Yonezawa, Suguru;
Sugihara, Kazumasa;
Yamashita, Sukehide;
Maruyama, Ikuro;
Tabata, M;
Yonezawa, S;
Sugihara, K;
Yamashita, S;
Maruyama, I

Publication type:

journal article

Effect of recombinant human soluble thrombomodulin on clinical outcomes of patients with coagulopathy after hematopoietic stem cell transplantation.

Published in:

European Journal of Haematology, 2013, v. 91, n. 5, p. 442, doi. 10.1111/ejh.12188

By:

Ikezoe, Takayuki;
Takeuchi, Asako;
Chi, SungGi;
Takaoka, Masato;
Anabuki, Kazuki;
Kim, Tsukie;
Sakai, Mizu;
Taniguchi, Ayuko;
Togitani, Kazuto;
Yokoyama, Akihito

Publication type:

Article

Soluble Thrombomodulin to Evaluate the Severity and Outcome of Community-Acquired Pneumonia.

Published in:

Inflammation, 2014, v. 37, n. 4, p. 1271, doi. 10.1007/s10753-014-9854-9

By:

Yin, Qin;
Liu, Bo;
Chen, Yunxia;
Zhao, Yunzhou;
Li, Chunsheng

Publication type:

Article

Vascular Endothelial Cell Injury Partly Induced by Mesenteric Lymph in Heat Stroke.

Published in:

Inflammation, 2014, v. 37, n. 1, p. 27, doi. 10.1007/s10753-013-9708-x

By:

Tong, HuaSheng;
Wan, Peng;
Zhang, XingQin;
Duan, PengKai;
Tang, YouQing;
Chen, Yi;
Tang, LiQun;
Su, Lei

Publication type:

Article

Whole exome sequencing identifies a mutation in thrombomodulin as the genetic cause of a suspected platelet disorder in a family with normal platelet function.

Published in:

Platelets, 2017, v. 28, n. 6, p. 611, doi. 10.1080/09537104.2017.1283011

By:

Maclachlan, Annabel;
Dolan, Gerry;
Grimley, Charlotte;
Watson, Steve P.;
Morgan, Neil V.;
on behalf of the UK GAPP Study Group

Publication type:

Article

Recombinant thrombomodulin lectin-like domain attenuates Porphyromonas gingivalis lipopolysaccharide-induced osteoclastogenesis and periodontal bone resorption.

Published in:

2021

By:

Chang, Lan‐Yun;
Lai, Chao‐Han;
Kuo, Cheng‐Hsiang;
Chang, Bi‐Ing;
Wu, Hua‐Lin;
Cheng, Tsung‐Lin;
Chang, Lan-Yun;
Lai, Chao-Han;
Kuo, Cheng-Hsiang;
Chang, Bi-Ing;
Wu, Hua-Lin;
Cheng, Tsung-Lin

Publication type:

journal article

Degradation of Vascular Endothelial Thrombomodulin by Arginine- and Lysine-Specific Cysteine Proteases From Porphyromonas gingivalis.

Published in:

Journal of Periodontology, 2009, v. 80, n. 9, p. 1511, doi. 10.1902/jop.2009.090114

By:

Inomata, Megumi;
Lshihara, Yuichi;
Matsuyama, Takashi;
Imamura, Takahisa;
Maruyama, Ikuro;
Noguchi, Toshihide;
Matsushita, Kenji

Publication type:

Article

A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/3605643

By:

Sittig, Simone P.;
Bakdash, Ghaith;
Weiden, Jorieke;
Sköld, Annette E.;
Tel, Jurjen;
Figdor, Carl G.;
de Vries, I. Jolanda M.;
Schreibelt, Gerty

Publication type:

Article

rTM reprograms macrophages via the HIF-1α/METTL3/PFKM axis to protect mice against sepsis.

Published in:

Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05489-5

By:

Yao, Chen;
Zhu, Hanyong;
Ji, Binbin;
Guo, Hui;
Liu, Zimeng;
Yang, Ni;
Zhang, Qi;
Hai, Kangning;
Gao, Chenbo;
Zhao, Jie;
Li, Xueqin;
Li, Rongqing;
Chen, Xin;
Meng, Fandong;
Pan, Xiucheng;
Fu, Chunling;
Cheng, Wanpeng;
Dong, Fuxing;
Yang, Jing;
Pan, Yuchen

Publication type:

Article

Thrombomodulin as a promising Marker of Endothelial Dysfunction in Hemodialysis Patients with Non Alcoholic Fatty Liver Disease.

Published in:

QJM: An International Journal of Medicine, 2024, v. 117, p. i114, doi. 10.1093/qjmed/hcae070.260

By:

Hebah, Hayam Ahmed;
Mohamed, Manal Sabry;
El-Nagar, Mohamed Kamel;
Abdelmegied, Shaimaa Zaki

Publication type:

Article

Evaluation of Serum level of thrombomodulin in cases with preeclampsia.

Published in:

QJM: An International Journal of Medicine, 2021, v. 114, p. i246, doi. 10.1093/qjmed/hcab115.036

By:

Abou Taleb, Yasser M.;
Mohammed, Hayam F.;
El-Khazragy, Nashwa N.;
Ahmed, Sohaila K.

Publication type:

Article

Role of Vascular Endothelial Growth Factor in Pulmonary Endothelial Cell Injury by Exercise Challenge in Asthmatic Patients.

Published in:

Journal of Asthma, 2006, v. 43, n. 4, p. 267, doi. 10.1080/02770900600622653

By:

Kanazawa, Hiroshi;
Tochino, Yoshihiro;
Ichimaru, Yukitoshi;
Kodama, Toyoki;
Kyoh, Shigenori;
Umeda, Nobuaki

Publication type:

Article

Enhanced Polymorphonuclear Neutrophil-Mediated Endothelial Cell Injury and Its Relation to High Surgical Mortality Rate in Cirrhotic Patients.

Published in:

American Journal of Gastroenterology (Springer Nature), 1999, v. 94, n. 11, p. 3297, doi. 10.1111/j.1572-0241.1999.01541.x

By:

Shimizu, Yoshiaki;
Miyazaki, Masaru;
Ito, Hiroshi;
Nakagawa, Koji;
Ambiru, Satoshi;
Shimizu, Hiroaki;
Nakamura, Shunta;
Okuno, Atushi;
Nozawa, Satoshi;
Nukui, Yuji;
Yoshitomi, Hideyuki;
Nakajim, Nobuyuki

Publication type:

Article

Early pathology in venom-induced consumption coagulopathy by Rhabdophis tigrinus (Yamakagashi snake) envenomation.

Published in:

2019

By:

Ichiki, Toshio;
Kohda, Futoshi;
Hiramatsu, Toshiki;
Saiki, Reo;
Sakai, Atsushi;
Furue, Masutaka

Publication type:

Case Study

The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin.

Published in:

EMBO Journal, 1997, v. 16, n. 11, p. 2977, doi. 10.1093/emboj/16.11.2977

By:

van de Locht, Andreas;
Bode, Wolfram;
Huber, Robert;
le Bonniec, Bernard F.;
Stone, Stuart R.;
Esmon, Charles T.;
Stubbs, Milton T.

Publication type:

Article

Recombinant Thrombomodulin Attenuates Preeclamptic Symptoms by Inhibiting High-Mobility Group Box 1 in Mice.

Published in:

Endocrinology, 2021, v. 162, n. 4, p. 1, doi. 10.1210/endocr/bqaa248

By:

Oda, Hiroko;
Nagamatsu, Takeshi;
Schust, Danny J;
Cabral, Horacio;
Miyazaki, Takuya;
Iriyama, Takayuki;
Kawana, Kei;
Osuga, Yutaka;
Fujii, Tomoyuki

Publication type:

Article

The envelope glycoprotein domain III of dengue virus type 2 induced the expression of anticoagulant molecules in endothelial cells.

Published in:

Molecular & Cellular Biochemistry, 2010, v. 342, n. 1/2, p. 215, doi. 10.1007/s11010-010-0486-6

By:

Chen, Lien-Cheng;
Yeh, Trai-Ming;
Lin, Yi-Ying;
Wang, Yi-Fen;
Su, Shu-Jem;
Chen, Chang-Yu;
Lin, Kuan-Hua;
Chou, Miao-Chen;
Shyu, Huey-Wen

Publication type:

Article

Effect of ageing on the murine venous circulation.

Published in:

Histochemistry & Cell Biology, 2012, v. 137, n. 4, p. 537, doi. 10.1007/s00418-012-0913-8

By:

Hemmeryckx, Bianca;
Emmerechts, Jan;
Bovill, Edwin;
Hoylaerts, Marc;
Lijnen, H.

Publication type:

Article

The endothelial microenvironment in the venous valvular sinus: thromboresistance trends and inter-individual variation.

Published in:

Histochemistry & Cell Biology, 2011, v. 135, n. 2, p. 141, doi. 10.1007/s00418-011-0783-5

By:

Trotman, W.;
Taatjes, D.;
Callas, P.;
Bovill, E.

Publication type:

Article

Localization of thrombomodulin in pericryptal fibroblasts of the rat duodenum.

Published in:

Histochemistry & Cell Biology, 2004, v. 121, n. 4, p. 311

By:

Daimon, Tateo;
Okuma, Yosimichi

Publication type:

Article