Works matching DE "THROMBIN receptors"

Results: 564

Protease-mediated activation of Par2 elicits calcium waves during zebrafish egg activation and blastomere cleavage.

Published in:

PLoS Biology, 2025, v. 23, n. 6, p. 1, doi. 10.1371/journal.pbio.3003181

By:

Ma, Jiajia;
Carney, Tom J.

Publication type:

Article

Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00859-4

By:

Dellar, Elizabeth R.;
Nikel, Lara;
Fowler, Stephanie;
Vahsen, Björn F.;
Dafinca, Ruxandra;
Feneberg, Emily;
Talbot, Kevin;
Turner, Martin R.;
Thompson, Alexander G.

Publication type:

Article

Neuroprotection induced by protease-activated receptor 2 activation is independent of Gq signalling.

Published in:

Brain & Neuroscience Advances, 2025, p. 1, doi. 10.1177/23982128251345673

By:

Moudio, Serge;
Nuthall, Hugh N.;
Bushell, Trevor J.

Publication type:

Article

Evidence for control of cerebral neurovascular function by circulating platelets in healthy older adults.

Published in:

Journal of Physiology, 2025, v. 603, n. 11, p. 3379, doi. 10.1113/JP288405

By:

Rossetti, Gabriella M. K.;
Dunster, Joanne L.;
Sohail, Aamir;
Williams, Brendan;
Cox, Kiera M.;
Rawlings, Suzannah;
Jewett, Elysia;
Benford, Eleanor;
Lovegrove, Julie A.;
Gibbins, Jonathan M.;
Christakou, Anastasia

Publication type:

Article

Blood Coagulation Factor IX: Structure, Function, and Regulation.

Published in:

IUBMB Life, 2025, v. 77, n. 5, p. 1, doi. 10.1002/iub.70024

By:

Ivanciu, Lacramioara;
Camire, Rodney M.

Publication type:

Article

Improved cytoreductive potential of plateletapheresis in the treatment of thrombocythemia: a single center study.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2019, v. 76, n. 5, p. 559, doi. 10.2298/VSP190219042B

By:

Balint, Bela;
Pavlović, Mirjana;
Ostojić, Gordana;
Vučetić, Dušan;
Todorović, Milena

Publication type:

Article

Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heart.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 2, p. 1, doi. 10.1007/s00395-019-0771-9

By:

Fender, Anke C.;
Kleeschulte, Sonja;
Stolte, Svenja;
Leineweber, Katja;
Kamler, Markus;
Bode, Johannes;
Li, Na;
Dobrev, Dobromir

Publication type:

Article

Extra-platelet low-molecular-mass thiols mediate the inhibitory action of S-nitrosoalbumin on human platelet aggregation via S-transnitrosylation of the platelet surface.

Published in:

Amino Acids, 2021, v. 53, n. 4, p. 563, doi. 10.1007/s00726-021-02950-8

By:

Tsikas, Dimitrios

Publication type:

Article

In vitro Investigation of Platelet Dysfunction Induced by Osmotic Pressure Variations.

Published in:

Medical Principles & Practice, 2023, v. 32, n. 4/5, p. 242, doi. 10.1159/000533852

By:

Pantazi, Despoina;
Stratou, Athina;
Dounousi, Evangelia;
Petrou, Anastasios;
Tselepis, Alexandros D.

Publication type:

Article

Expression of Concern: Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.

Published in:: Biochemical Journal, 2024, v. 481, n. 7, p. 567, doi. 10.1042/BCJ20170272_EOC
Publication type:: Article

Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants.

Published in:

Biochemical Journal, 2022, v. 479, n. 6, p. 731, doi. 10.1042/BCJ20210522

By:

Ryan, Tristram A. J.;
Preston, Roger J. S.;
O'Neill, Luke A. J.

Publication type:

Article

3D Human iPSC Blood Vessel Organoids as a Source of Flow‐Adaptive Vascular Cells for Creating a Human‐Relevant 3D‐Scaffold Based Macrovessel Model.

Published in:

Advanced Biology, 2023, v. 7, n. 1, p. 1, doi. 10.1002/adbi.202200137

By:

Meijer, Elana M.;
Koch, Suzanne E.;
van Dijk, Christian G.M.;
Maas, Renee G.C.;
Chrifi, Ihsan;
Szymczyk, Wojciech;
Besseling, Paul J.;
Pomp, Lisa;
Koomen, Vera J.C.H.;
Buikema, Jan Willem;
Bouten, Carlijn V.C.;
Verhaar, Marianne C.;
Smits, Anthal I.P.M.;
Cheng, Caroline

Publication type:

Article

Isolation and Biological Evaluation of Alfa-Mangostin as Potential Therapeutic Agents against Liver Fibrosis.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 9, p. 1075, doi. 10.3390/bioengineering10091075

By:

Liao, Yi-Jen;
Lee, Chun-Ya;
Twu, Yuh-Ching;
Suk, Fat-Moon;
Lai, Tzu-Chieh;
Chang, Ya-Ching;
Lai, Yi-Cheng;
Yuan, Jing-Wei;
Jhuang, Hong-Ming;
Jian, Huei-Ruei;
Huang, Li-Chia;
Chen, Kuang-Po;
Hsu, Ming-Hua

Publication type:

Article

Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1990, doi. 10.3390/jcm8111990

By:

Makhoul, Stephanie;
Panova-Noeva, Marina;
Regnault, Véronique;
Ruf, Wolfram;
Wenzel, Philip;
Lagrange, Jeremy

Publication type:

Article

Embelin as a Novel Inhibitor of PKC in the Prevention of Platelet Activation and Thrombus Formation.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1724, doi. 10.3390/jcm8101724

By:

Li, Jiun Yi;
Chen, Ray Jade;
Huang, Li Ting;
Lee, Tzu Yin;
Lu, Wan Jung;
Lin, Kuan Hung

Publication type:

Article

Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1570, doi. 10.3390/jcm8101570

By:

Hasan, Hira;
Park, Sin-Hee;
Auger, Cyril;
Belcastro, Eugenia;
Matsushita, Kensuke;
Marchandot, Benjamin;
Lee, Hyun-Ho;
Qureshi, Abdul Wahid;
Kauffenstein, Gilles;
Ohlmann, Patrick;
Schini-Kerth, Valérie B;
Jesel, Laurence;
Morel, Olivier

Publication type:

Article

Peptide Antagonists for P-selectin Discriminate between Sulfatide-Dependent Platelet Aggregation and PSGL-1-Mediated Cell Adhesion.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 8, p. 1266, doi. 10.3390/jcm8081266

By:

Korporaal, Suzanne J.A.;
Molenaar, Tom J.M.;
Lutters, Bianca C.H.;
Meurs, Illiana;
Drost-Verhoef, Sandra;
Kuiper, Johan;
van Berkel, Theo J.C.;
Biessen, Erik A.L.

Publication type:

Article

Anti-thrombotic effects of arteanoflavone by regulating cyclic nucleotides and aggregation on human platelets.

Published in:

Applied Biological Chemistry, 2024, v. 67, n. 1, p. 1, doi. 10.1186/s13765-024-00914-6

By:

Choi, Ho Keun;
Kim, Ga Yeon;
Lee, Ga Hee;
su Jang, Hee;
Kang, Da Hyeon;
Lee, Jin Pyo;
Lee, Dong-Ha

Publication type:

Article

Artocarpesin acts on human platelet aggregation through inhibition of cyclic nucleotides and MAPKs.

Published in:

Applied Biological Chemistry, 2022, v. 65, n. 1, p. 1, doi. 10.1186/s13765-022-00694-x

By:

Kwon, Hyuk-Woo;
Irfan, Muhammad;
Lee, Yuan Yee;
Rhee, Man Hee;
Shin, Jung-Hae

Publication type:

Article

CYP3A4*22 may increase bleeding risk in ticagrelor users.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 2, p. 202, doi. 10.1111/bcpt.13884

By:

Liedes, Hilkka;
Pajula, Juha;
Vuorinen, Anna‐Leena;
De Pretis, Francesco;
van Gils, Mark;
Harno, Kari;
Lehto, Mika;
Niemi, Mikko;
Lähteenmäki, Jaakko

Publication type:

Article

Protease-activated receptor-2 activation enhances epithelial wound healing via epidermal growth factor receptor.

Published in:

Tissue Barriers, 2022, v. 10, n. 2, p. 1, doi. 10.1080/21688370.2021.1968763

By:

Bandara, Mahesha;
MacNaughton, Wallace K.

Publication type:

Article

Plasma viscosity, functional fibrinogen, and platelet reactivity in vascular surgery patients.

Published in:

Clinical Hemorheology & Microcirculation, 2015, v. 61, n. 3, p. 417, doi. 10.3233/CH-141866

By:

Ranucci, Marco;
Ranucci, Matteo;
Laddomada, Tommaso;
Baryshnikova, Ekaterina;
Nano, Giovanni;
Trimarchi, Santi

Publication type:

Article

CD74 in Apoptotic Macrophages Is Associated with Inflammation, Plaque Progression and Clinical Manifestations in Human Atherosclerotic Lesions.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 1, p. 54, doi. 10.3390/metabo12010054

By:

Li, Wei;
Sultana, Nargis;
Yuan, Linda;
Forssell, Claes;
Yuan, Xi-Ming

Publication type:

Article

ADAMTS13, von Willebrand Factor, Platelet Microparticles, Factor VIII, and Impact of Somatic Mutations in the Pathogenesis of Splanchnic Vein Thrombosis Associated with BCR-ABL-Negative Myeloproliferative Neoplasms.

Published in:

Life (2075-1729), 2024, v. 14, n. 4, p. 486, doi. 10.3390/life14040486

By:

Castelli, Roberto;
Berzuini, Alessandra;
Manetti, Roberto;
Delitala, Alessandro Palmerio;
Castro, Dante;
Sanna, Giuseppe;
Sircana, Marta Chiara;
Profili, Nicia Isabella;
Bartoli, Arianna;
La Cava, Leyla;
Lambertenghi Deliliers, Giorgio;
Donadoni, Mattia;
Gidaro, Antonio

Publication type:

Article

Platelet Glycoprotein-Ib (GPIb) May Serve as a Bridge between Type 2 Diabetes Mellitus (T2DM) and Atherosclerosis, Making It a Potential Target for Antiplatelet Agents in T2DM Patients.

Published in:

Life (2075-1729), 2023, v. 13, n. 7, p. 1473, doi. 10.3390/life13071473

By:

Amalia, Muttia;
Puteri, Meidi Utami;
Saputri, Fadlina Chany;
Sauriasari, Rani;
Widyantoro, Bambang

Publication type:

Article

Endothelial Dysfunction in COVID-19: Potential Mechanisms and Possible Therapeutic Options.

Published in:

Life (2075-1729), 2022, v. 12, n. 10, p. 1605, doi. 10.3390/life12101605

By:

Pelle, Maria Chiara;
Zaffina, Isabella;
Lucà, Stefania;
Forte, Valentina;
Trapanese, Vincenzo;
Melina, Melania;
Giofrè, Federica;
Arturi, Franco

Publication type:

Article

Linagliptin Regulates the Mitochondrial Respiratory Reserve to Alter Platelet Activation and Arterial Thrombosis.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.585612

By:

Li, Yi;
Li, Rong;
Feng, Ziqian;
Wan, Qin;
Wu, Jianbo

Publication type:

Article

Interplay Between Angiotensin II Type 1 Receptor and Thrombin Receptor Revealed by Bioluminescence Resonance Energy Transfer Assay.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01283

By:

Zamel, Isra Al;
Palakkott, Abdulrasheed;
Ashraf, Arshida;
Iratni, Rabah;
Ayoub, Mohammed Akli

Publication type:

Article

Bacterial aggregation facilitates internalin-mediated invasion of Listeria monocytogenes.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 1, doi. 10.3389/fcimb.2024.1411124

By:

Feltham, Liam;
Moran, Josephine;
Goldrick, Marie;
Lord, Elizabeth;
Spiller, David G.;
Cavet, Jennifer S.;
Muldoon, Mark;
Roberts, Ian. S.;
Paszek, Pawel

Publication type:

Article

Селективний антагоніст протеазоактивованих рецепторів 1 нормалізує рівень емоційної збудливості щурів у латентній стадії формування скроневої епілепсії.

Published in:

Physiological Journal / Fiziologichnyi Zhurnal, 2019, v. 65, n. 3, p. 7

By:

Semenikhina, M.;
Bogovik, R.;
Fedoryuk, M.;
Lunko, O.;
Savotchenko, A.;
Isaeva, E.

Publication type:

Article

Roles of miR-223 in Platelet Function and High On-Treatment Platelet Reactivity: A Brief Report and Review.

Published in:

Genes, 2025, v. 16, n. 3, p. 312, doi. 10.3390/genes16030312

By:

Askari, Shayan;
Goldfinger, Lawrence E.

Publication type:

Article

In Vitro Antiplatelet Activity of Mulberroside C through the Up-Regulation of Cyclic Nucleotide Signaling Pathways and Down-Regulation of Phosphoproteins.

Published in:

Genes, 2021, v. 12, n. 7, p. 1024, doi. 10.3390/genes12071024

By:

Kwon, Hyuk-Woo;
Lee, Dong-Ha;
Rhee, Man Hee;
Shin, Jung-Hae

Publication type:

Article

Molecular Docking Study of New Sorafenib Analogues as Platelet-Derived Growth Factor Receptor Inhibitors for the Treatment of Cancer.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2023, v. 15, p. S1023, doi. 10.4103/jpbs.jpbs_244_23

By:

Jihad, Marwan I.;
Mahdi, Monther F.

Publication type:

Article

Fast Force Loading Disrupts Molecular Bond Stability in Human and Mouse Cell Adhesions.

Published in:

Molecular & Cellular Biomechanics, 2019, v. 16, p. 97, doi. 10.32604/mcb.2019.07123

By:

Yunfeng Chen;
Jiexi Liao;
Zhou Yuan;
Kaitao Li;
Baoyu Liu;
Ju, Lining Arnold;
Cheng Zhu

Publication type:

Article

Autodigestion in Physiological Shock, Organ Dysfunction and Death.

Published in:

Molecular & Cellular Biomechanics, 2019, v. 16, p. 8, doi. 10.32604/mcb.2019.07256

By:

Kistler, Erik B.;
Schmid-Schönbein, Geert W.

Publication type:

Article

Fast Force Loading Disrupts Molecular Binding Stability in Human and Mouse Cell Adhesions.

Published in:

Molecular & Cellular Biomechanics, 2019, v. 16, n. 3, p. 211, doi. 10.32604/mcb.2019.07267

By:

Yunfeng Chen;
Jiexi Liao;
Zhou Yuan;
Kaitao Li;
Baoyu Liu;
Ju, Lining Arnold;
Cheng Zhu

Publication type:

Article

Developmental Differences in Platelet Inhibition Response to Prostaglandin E1.

Published in:

Neonatology (16617800), 2020, v. 117, n. 1, p. 15, doi. 10.1159/000504173

By:

Palma-Barqueros, Verónica;
Torregrosa, José Miguel;
Caparrós-Pérez, Eva;
Mota-Pérez, Nerea;
Bohdan, Natalia;
Llanos, María del Carmen;
Begonja, Antonija Jurak;
Sola-Visner, Martha;
Vicente, Vicente;
Teruel-Montoya, Raúl;
Rivera, José;
Ferrer-Marín, Francisca

Publication type:

Article

Uncovering Streptomyces -Derived Compounds as Cosmeceuticals for the Development of Improved Skin Photoprotection Products: An In Silico Approach to Explore Multi-Targeted Agents.

Published in:

Scientia Pharmaceutica, 2022, v. 90, n. 3, p. 48, doi. 10.3390/scipharm90030048

By:

Sánchez-Suárez, Jeysson;
Villamil, Luisa;
Díaz, Luis;
Coy-Barrera, Ericsson

Publication type:

Article

Modulation of the Thrombin Pathway Restores LTP in a Pilocarpine Mice Model of Status Epilepticus.

Published in:

Frontiers in Cellular Neuroscience, 2022, p. 1, doi. 10.3389/fncel.2022.900925

By:

Shavit-Stein, Efrat;
Berkowitz, Shani;
Davidy, Tal;
Fennig, Uri;
Gofrit, Shani Guly;
Dori, Amir;
Maggio, Nicola

Publication type:

Article

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c.

Published in:

Nature Medicine, 2013, v. 19, n. 12, p. 1609, doi. 10.1038/nm.3385

By:

Edelstein, Leonard C;
Simon, Lukas M;
Montoya, Raúl Teruel;
Holinstat, Michael;
Chen, Edward S;
Bergeron, Angela;
Kong, Xianguo;
Nagalla, Srikanth;
Mohandas, Narla;
Cohen, David E;
Dong, Jing-fei;
Shaw, Chad;
Bray, Paul F

Publication type:

Article

Recombinant hirudin suppresses angiogenesis of diffuse large B‐cell lymphoma through regulation of the PAR‐1‐VEGF.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 5, p. 1, doi. 10.1111/cbdd.14533

By:

Zhao, Jingjing;
Li, Zihui;
Zhang, Haixi;
Qin, Tao;
Zhao, Juan;
Pei, Qiang

Publication type:

Article

Kisspeptin/KISS1R Signaling Modulates Human Airway Smooth Muscle Cell Migration.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 6, p. 507, doi. 10.1165/rcmb.2023-0469OC

By:

Balraj, Premanand;
Ambhore, Nilesh Sudhakar;
Ramakrishnan, Yogaraj S.;
Borkar, Niyati A.;
Banerjee, Priyanka;
Reza, Mohammad Irshad;
Varadharajan, Subashini;
Kumar, Ashish;
Pabelick, Christina M.;
Prakash, Y. S.;
Sathish, Venkatachalem

Publication type:

Article

Augmentation Therapy Decreases Platelet-Neutrophil Aggregates in Alpha-1 Antitrypsin Deficiency.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 6, p. 524, doi. 10.1165/rcmb.2023-0417LE

By:

Lacey, Noreen;
Teo, Jolene Y. Q.;
Baird, Rory;
Forde, Luke;
Hawkins, Padraig;
McEnery, Tom;
Lee, Melvin Q.;
Hoo, Melvin C. S.;
Gogoi, Debananda;
Reeves, Emer P.

Publication type:

Article

Protease-activated receptor type 1 (PAR1) increases CEMP1 gene expression through MAPK/ERK pathway.

Published in:

Brazilian Oral Research, 2022, v. 36, p. 1, doi. 10.1590/1807-3107bor-2022.vol36.0048

By:

ROVAI, Emanuel Silva;
ALVES, Tomaz;
GASPARONI, Letícia Miquelitto;
de FRANÇA, Bruno Nunes;
SIPERT, Carla Renata;
KANTARCI, Alpdogan;
HOLZHAUSEN, Marinella

Publication type:

Article

Role of Liver Kinase 1B in Platelet Activation and Host Defense During Klebsiella pneumoniae -Induced Pneumosepsis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3714, doi. 10.3390/ijms26083714

By:

Chouchane, Osoul;
Léopold, Valentine;
van Linge, Christine C. A.;
de Vos, Alex F.;
Roelofs, Joris J. T. H.;
van 't Veer, Cornelis;
van der Poll, Tom

Publication type:

Article

Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01717-4

By:

Fuentes-Mateos, Rocío;
García-Navas, Rósula;
Fernández-Infante, Cristina;
Hernández-Cano, Luis;
Calzada-Nieto, Nuria;
Juan, Andrea Olarte-San;
Guerrero, Carmen;
Santos, Eugenio;
Fernández-Medarde, Alberto

Publication type:

Article

The effect of clopidogrel on platelet activity in patients with and without type-2 diabetes mellitus: a comparative study.

Published in:

Cardiovascular Diabetology, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12933-015-0182-7

By:

Schuette, Claudia;
Steffens, Daniel;
Witkowski, Marco;
Stellbaum, Caroline;
Bobbert, Peter;
Schultheiss, Heinz-Peter;
Rauch, Ursula

Publication type:

Article

Point-of-care thrombocyte function testing using multiple-electrode aggregometry in dengue patients: an explorative study.

Published in:

2020

By:

de Jong, Wesley;
Asmarawati, Tri Pudy;
Verbeek, Inge;
Rusli, Musofa;
Hadi, Usman;
van Gorp, Eric;
Goeijenbier, Marco

Publication type:

journal article

Angiopoietin-like protein 2 inhibits thrombus formation.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 2, p. 1169, doi. 10.1007/s11010-024-05034-9

By:

Zhang, Tiantian;
Zhang, Mingliang;
Guo, Lingyu;
Liu, Dongsheng;
Zhang, Kandi;
Bi, Changlong;
Zhang, Peng;
Wang, Jin;
Fan, Yuqi;
He, Qing;
Chang, Alex C. Y.;
Zhang, Junfeng

Publication type:

Article

Screening and identification of differential-expressed RNAs in thrombin-induced in vitro model of intracerebral hemorrhage.

Published in:

Molecular & Cellular Biochemistry, 2024, v. 479, n. 10, p. 2755, doi. 10.1007/s11010-023-04879-w

By:

Gao, Ling;
Peng, Li;
Tang, Hong;
Wang, Chuang;
Wang, Qingsong;
Luo, Yujie;
Chen, Weiming;
Xia, Ying

Publication type:

Article