Works matching DE "THERAPEUTIC use of RNA interference"

Results: 80

ZFX regulates glioma cell proliferation and survival in vitro and in vivo.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 17, doi. 10.1007/s11060-012-1032-z

By:

Zhu, Zhichuan;
Li, Kui;
Xu, Dafeng;
Liu, Yongjie;
Tang, Hailiang;
Xie, Qing;
Xie, Liqian;
Liu, Jiwei;
Wang, Hongtao;
Gong, Ye;
Hu, Zelan;
Zheng, Jing

Publication type:

Article

Knockdown of RLIP76 expression by RNA interference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 73, doi. 10.1007/s11060-013-1045-2

By:

Wang, Qi;
Qian, Jun;
Wang, JunYu;
Luo, Chun;
Chen, Juxiang;
Hu, Guohan;
Lu, Yicheng

Publication type:

Article

Zilebesiran Reduces SBP on Background SOC in Uncontrolled HTN: Daily Dose.

Published in:

Patient Care (Online), 2024, p. 1

By:

Jennings, Sydney

Publication type:

Article

RNA interference technology with emphasis on delivery vehicles—prospects and limitations.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 6, p. 1391, doi. 10.3109/21691401.2015.1058808

By:

Prabha, Shashi;
Vyas, Ruchi;
Gupta, Nidhi;
Ahmed, Bahar;
Chandra, Ramesh;
Nimesh, Surendra

Publication type:

Article

Down-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 5, p. 1201, doi. 10.3109/21691401.2015.1029628

By:

Zhang, Junwei;
Du, Jiajun;
Liu, Qi;
Zhang, Yi

Publication type:

Article

Antiapoptotic Bcl-2 protein as a potential target for cancer therapy: A mini review.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 5, p. 1212, doi. 10.3109/21691401.2015.1019668

By:

Jagani, Hitesh;
Kasinathan, Narayanan;
Meka, Sreenivasa Reddy;
Josyula, Venkata Rao

Publication type:

Article

Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 2, p. 696, doi. 10.3892/mmr.2016.6085

By:

Xin-Hua Zhu;
Bing Liao;
Yi Xu;
Ke Liu;
Yun Huang;
Quan-Long Huang;
Yue-Hui Liu

Publication type:

Article

Effects of cyclooxygenase-2 gene silencing on the biological behavior of SKOV3 ovarian cancer cells.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 1, p. 59, doi. 10.3892/mmr.2014.2732

By:

FENG-JUN GUO;
JING-YAN TIAN;
YUE-MEI JIN;
LING WANG;
RUI-QI YANG;
MAN-HUA CUI

Publication type:

Article

SYNTHESIS AND CHARACTERIZATION OF GRP78 SIRNAS FOR SILENCING GENE EXPRESSION IN HEPG2 LIVER CARCINOMA CELLS.

Published in:

Bulletin: New Jersey Academy of Science, 2014, v. 59, n. 1, p. 1

By:

MAINA, ANTHONY;
MOROZKO, EVA;
BENDER, MARIA E.;
BLACKMAN, BRITTANY;
PARRONCHI, CHRIS;
BLAKE, ALLAN D.;
SABATINO, DAVID

Publication type:

Article

Down-regulation of G protein-coupled receptor 137 by RNA interference inhibits cell growth of two hepatoma cell lines.

Published in:

Cell Biology International, 2015, v. 39, n. 4, p. 418, doi. 10.1002/cbin.10412

By:

Shao, Xin;
Liu, Yong;
Huang, Hai;
Zhuang, Linyuan;
Luo, Tianping;
Huang, Huping;
Ge, Xinguo

Publication type:

Article

RNA interference-based therapeutics for inherited long QT syndrome (Review).

Published in:

Experimental & Therapeutic Medicine, 2015, v. 10, n. 2, p. 395, doi. 10.3892/etm.2015.2573

By:

GUOLIANG LI;
SHUTING MA;
CHAOFENG SUN

Publication type:

Article

Design of siRNA Therapeutics from the Molecular Scale.

Published in:

Pharmaceuticals (14248247), 2013, v. 6, n. 4, p. 440, doi. 10.3390/ph6040440

By:

Angart, Phillip;
Vocelle, Daniel;
Chan, Christina;
Patrick Walton, S.

Publication type:

Article

Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges.

Published in:

Pharmaceuticals (14248247), 2013, v. 6, n. 1, p. 85, doi. 10.3390/ph6010085

By:

Jiehua Zhou;
Ka-To Shum;
Burnett, John C.;
Rossi, John J.

Publication type:

Article

Medical applications of RNA interference (RNAi).

Published in:

BMC Proceedings, 2013, v. 7, n. Suppl 2, p. 1, doi. 10.1186/1753-6561-7-S2-K21

By:

Pereira, Tiago Campos;
Lopes-Cendes, Iscia

Publication type:

Article

Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

Published in:

Bioscience Reports, 2014, v. 34, n. 2, p. 93, doi. 10.1042/BSR20140010

By:

FALK, Matthew D.;
Wei LIU;
BOLAÑOS, Ben;
UNSAL-KACMAZ, Keziban;
KLIPPEL, Anke;
GRANT, Stephan;
BROOUN, Alexei;
TIMOFEEVSKI, Sergei

Publication type:

Article

Effective inhibition of porcine epidemic diarrhea virus by RNA interference in vitro.

Published in:

Virus Genes, 2015, v. 51, n. 2, p. 252, doi. 10.1007/s11262-015-1242-5

By:

Shen, Haiyan;
Zhang, Chunhong;
Guo, Pengju;
Liu, Zhicheng;
Zhang, Jianfeng

Publication type:

Article

A Mutation-Independent Therapeutic Strategy for Dominant Dystrophic Epidermolysis Bullosa.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 12, p. 2793, doi. 10.1038/jid.2013.241

By:

Morgan, Clare P;
Allen, Danny S I;
Millington-Ward, Sophia;
O'Dwyer, Gareth E;
Palfi, Arpad;
Farrar, G Jane

Publication type:

Article

Overview of RNA interference therapeutics.

Published in:

Songklanakarin Journal of Science & Technology, 2012, v. 34, n. 3, p. 293

By:

Panjaworayan, Nattanan T-Thienprasert

Publication type:

Article

Comparative Transcriptome Analyses Uncover Key Candidate Genes Mediating Flight Capacity in Bactrocera dorsalis (Hendel) and Bactrocera correcta (Bezzi) (Diptera: Tephritidae).

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 396, doi. 10.3390/ijms19020396

By:

Guo, Shaokun;
Zhao, Zihua;
Liu, Lijun;
Li, Zhihong;
Shen, Jie

Publication type:

Article

Development of Small RNA Delivery Systems for Lung Cancer Therapy.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 3, p. 5254, doi. 10.3390/ijms16035254

By:

Yu Fujita;
Kazuyoshi Kuwano;
Takahiro Ochiya

Publication type:

Article

Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 398, n. 1/2, p. 11, doi. 10.1007/s11010-014-2200-6

By:

Zhou, Weibing;
Wang, Zhan;
Shen, Ni;
Pi, Weiwei;
Jiang, Wuzhong;
Huang, Juan;
Hu, Yuanping;
Li, Xiong;
Sun, Lunquan

Publication type:

Article

Correction to: The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market.

Published in:

2018

By:

Titze-de-Almeida, Ricardo;
David, Catherine;
Titze-de-Almeida, Simoneide Souza

Publication type:

Correction Notice

Hemocompatibility Assessment of two siRNA Nanocarrier Formulations.

Published in:

Pharmaceutical Research, 2014, v. 31, n. 11, p. 3127, doi. 10.1007/s11095-014-1405-4

By:

Yousefi, Afrouz;
Lauwers, Marianne;
Nemes, Reka;
Holten, Thijs;
Babae, Negar;
Roest, Mark;
Storm, Gert;
Schiffelers, Raymond;
Mastrobattista, Enrico

Publication type:

Article

The antisense 5' end of the V2 gene confers enhanced resistance against the monopartite begomovirus cotton leaf curl Kokhran virus-Burewala strain.

Published in:

Acta Virologica, 2019, v. 63, n. 1, p. 26, doi. 10.4149/av_2019_101

By:

ALI, I.;
KHURSHID, M.;
IQBAL, Z.;
SHAFIQ, M.;
AMIN, I.;
MANSOOR, S.;
BRIDDON, R. W.

Publication type:

Article

R049: Airway Injury Model for the Application of RNAi Therapy.

Published in:

2006

By:

Senchak, Andrew J.;
Bothwell, Nici Eddy;
Shvidler, Joseph;
Cable, Benjamin B

Publication type:

Abstract

Nanotechnology: RNAi-based nanoparticles zap glioblastoma.

Published in:

Nature Reviews Drug Discovery, 2014, v. 13, n. 1, p. 20, doi. 10.1038/nrd4214

By:

Harrison, Charlotte

Publication type:

Article

Trial watch: Pioneering RNAi therapy shows antitumour activity in humans.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 3, p. 178, doi. 10.1038/nrd3962

By:

Crunkhorn, Sarah

Publication type:

Article

Tolerogenic dendritic cells produced by lentiviral-mediated CD40- and interleukin-23p19-specific shRNA can ameliorate experimental autoimmune encephalomyelitis by suppressing T helper type 17 cells.

Published in:

Clinical & Experimental Immunology, 2014, v. 176, n. 2, p. 180, doi. 10.1111/cei.12266

By:

Kalantari, T.;
Karimi, M. H.;
Ciric, B.;
Yan, Y.;
Rostami, A.;
Kamali‐Sarvestani, E.

Publication type:

Article

miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.

Published in:

Cellular Oncology (2211-3428), 2016, v. 39, n. 1, p. 23, doi. 10.1007/s13402-015-0247-3

By:

Riquelme, Ismael;
Tapia, Oscar;
Sandoval, Alejandra;
Buchegger, Kurt;
Leal, Pamela;
Varga, Matthew;
Peek, Richard;
Letelier, Pablo;
Bizama, Carolina;
Espinoza, Jaime;
Roa, Juan;
Araya, Juan

Publication type:

Article

Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo.

Published in:

Gastroenterology Research & Practice, 2013, p. 1, doi. 10.1155/2013/685150

By:

Song He;
Ying-ze Wei;
Gui-lan Wang;
Yu-yin Xu;
Jia-ming Zhou;
Yi-xin Zhang;
Li Chen

Publication type:

Article

Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference.

Published in:

Molecular Therapy, 2014, v. 22, n. 4, p. 692, doi. 10.1038/mt.2013.285

By:

Borel, Florie;
Kay, Mark A;
Mueller, Christian

Publication type:

Article

Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection.

Published in:

Molecular Therapy, 2013, v. 21, n. 5, p. 973, doi. 10.1038/mt.2013.31

By:

Wooddell, Christine I;
Rozema, David B;
Hossbach, Markus;
John, Matthias;
Hamilton, Holly L;
Chu, Qili;
Hegge, Julia O;
Klein, Jason J;
Wakefield, Darren H;
Oropeza, Claudia E;
Deckert, Jochen;
Roehl, Ingo;
Jahn-Hofmann, Kerstin;
Hadwiger, Philipp;
Vornlocher, Hans-Peter;
McLachlan, Alan;
Lewis, David L

Publication type:

Article

Therapeutic Effects of MicroRNA-582-5p and -3p on the Inhibition of Bladder Cancer Progression.

Published in:

Molecular Therapy, 2013, v. 21, n. 3, p. 610, doi. 10.1038/mt.2012.269

By:

Uchino, Keita;
Takeshita, Fumitaka;
Takahashi, Ryou-u;
Kosaka, Nobuyoshi;
Fujiwara, Kae;
Naruoka, Haruna;
Sonoke, Satoru;
Yano, Junichi;
Sasaki, Hideo;
Nozawa, Shiari;
Yoshiike, Miki;
Kitajima, Kazuki;
Chikaraishi, Tatsuya;
Ochiya, Takahiro

Publication type:

Article

Novel Protein Transduction Domain Mimics as Nonviral Delivery Vectors for siRNA Targeting NOTCH1 in Primary Human T cells.

Published in:

Molecular Therapy, 2013, v. 21, n. 1, p. 201, doi. 10.1038/mt.2012.209

By:

Tezgel, A. Özgül;
Gonzalez-Perez, Gabriela;
Telfer, Janice C.;
Osborne, Barbara A.;
Minter, Lisa M.;
Tew, Gregory N.

Publication type:

Article

The emerging role of epigenetics in pulmonary arterial hypertension: an important avenue for clinical trials (2015 Grover Conference Series).

Published in:

Pulmonary Circulation, 2016, v. 6, n. 3, p. 274, doi. 10.1086/687765

By:

Huston, Jessica H.;
Ryan, John J.

Publication type:

Article

SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 6081, doi. 10.2147/OTT.S170482

By:

Chen, Changhao;
Zhang, Zhiwei;
Li, Jie;
Sun, Yuejun

Publication type:

Article

Ultrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 3539, doi. 10.2147/OTT.S94800

By:

Cheng-Shi Chen;
Qing Zhao;
Sheng Qian;
Hai-Liang Li;
Chen-Yang Guo;
Wei Zhang;
Zhi-Ping Yan;
Rong Liu;
Jian-Hua Wang

Publication type:

Article

Engineering Multifunctional RNAi Nanomedicine To Concurrently Target Cancer Hallmarks for Combinatorial Therapy.

Published in:

Angewandte Chemie, 2018, v. 130, n. 6, p. 1526, doi. 10.1002/ange.201710144

By:

Liu, Yanlan;
Ji, Xiaoyuan;
Tong, Winnie W. L.;
Askhatova, Diana;
Yang, Tingyuan;
Cheng, Hongwei;
Wang, Yuzhuo;
Shi, Jinjun

Publication type:

Article

Silencing human genetic diseases with oligonucleotide-based therapies.

Published in:

Human Genetics, 2013, v. 132, n. 5, p. 481, doi. 10.1007/s00439-013-1288-1

By:

Martínez, Tamara;
Wright, Natalia;
López-Fraga, Marta;
Jiménez, Ana;
Pañeda, Covadonga

Publication type:

Article

Gene silencing in tick cell lines using small interfering or long double-stranded RNA.

Published in:

Experimental & Applied Acarology, 2013, v. 59, n. 3, p. 319, doi. 10.1007/s10493-012-9598-x

By:

Barry, Gerald;
Alberdi, Pilar;
Schnettler, Esther;
Weisheit, Sabine;
Kohl, Alain;
Fazakerley, John;
Bell-Sakyi, Lesley

Publication type:

Article

Silencing of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human lung cancer cells.

Published in:

Oncology Letters, 2016, v. 11, n. 6, p. 3735, doi. 10.3892/ol.2016.4451

By:

XUANYU HU;
WEI GUO;
SHANSHAN CHEN;
YIZHUO XU;
PING LI;
HUAQI WANG;
HEYING CHU;
JUAN LI;
YUWEN DU;
XIAONAN CHEN;
GUOJUN ZHANG;
GUOQIANG ZHAO

Publication type:

Article

Combined RNAi targeting human Stat3 and ADAM9 as gene therapy for non-small cell lung cancer.

Published in:

Oncology Letters, 2016, v. 11, n. 2, p. 1242, doi. 10.3892/ol.2015.4018

By:

LIANG CHANG;
FANGCHAO GONG;
HONGFEI CAI;
ZHIHONG LI;
YOUBIN CUI

Publication type:

Article

Oncolytic adenovirus-expressed RNA interference of O<sup>6</sup>-methylguanine DNA methyltransferase activity may enhance the antitumor effects of temozolomide.

Published in:

Oncology Letters, 2014, v. 8, n. 5, p. 2201, doi. 10.3892/ol.2014.2442

By:

XIN-JUN CHEN;
KAI ZHANG;
YONG XIN;
GUAN JIANG

Publication type:

Article

Big pharma shows signs of renewed interest in RNAi drugs.

Published in:

Nature Medicine, 2014, v. 20, n. 2, p. 109, doi. 10.1038/nm0214-109

By:

Zeliadt, Nicholette

Publication type:

Article

CD22ΔE12 as a molecular target for RNAi therapy.

Published in:

British Journal of Haematology, 2015, v. 169, n. 3, p. 401, doi. 10.1111/bjh.13306

By:

Uckun, Fatih M.;
Ma, Hong;
Cheng, Jianjun;
Myers, Dorothea E.;
Qazi, Sanjive

Publication type:

Article

Adipocyte ATP-Binding Cassette G1 Promotes Triglyceride Storage, Fat Mass Growth, and Human Obesity.

Published in:

Diabetes, 2015, v. 64, n. 3, p. 840, doi. 10.2337/db14-0245

By:

Frisdal, Eric;
Le Lay, Soazig;
Hooton, Henri;
Poupel, Lucie;
Olivier, Maryline;
Alili, Rohia;
Plengpanich, Wanee;
Villard, Elise F.;
Gilibert, Sophie;
Lhomme, Marie;
Superville, Alexandre;
Miftah-Alkhair, Lobna;
Chapman, M. John;
Dallinga-Thie, Geesje M.;
Venteclef, Nicolas;
Poitou, Christine;
Tordjman, Joan;
Lesnik, Philippe;
Kontush, Anatol;
Huby, Thierry

Publication type:

Article

At the hypusine of the crime.

Published in:

2012

By:

Burgess, Darren J.

Publication type:

journal article

Understanding the antiviral effects of RNAi-based therapy in HBeAg-positive chronic hepatitis B infection.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80594-6

By:

Kadelka, Sarah;
Dahari, Harel;
Ciupe, Stanca M.

Publication type:

Article

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine.

Published in:

Polymers (20734360), 2018, v. 10, n. 9, p. 953, doi. 10.3390/polym10090953

By:

Yin, Yue;
Lee, Jung Eun;
Kim, Nak Won;
Lee, Jong Han;
Lim, Su Yeon;
Kim, E Seul;
Park, Ji Won;
Lee, Min Sang;
Jeong, Ji Hoon

Publication type:

Article

Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.

Published in:

Pharmacogenomics & Personalized Medicine, 2017, v. 10, p. 267, doi. 10.2147/PGPM.S87945

By:

Rizk, Malak;
Tüzmen, Şükrü

Publication type:

Article