Works matching DE "THERAPEUTIC use of RNA interference"
Results: 79
Effective inhibition of porcine epidemic diarrhea virus by RNA interference in vitro.
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- Virus Genes, 2015, v. 51, n. 2, p. 252, doi. 10.1007/s11262-015-1242-5
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Tolerogenic dendritic cells produced by lentiviral-mediated CD40- and interleukin-23p19-specific shRNA can ameliorate experimental autoimmune encephalomyelitis by suppressing T helper type 17 cells.
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- Clinical & Experimental Immunology, 2014, v. 176, n. 2, p. 180, doi. 10.1111/cei.12266
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miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.
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- Cellular Oncology (2211-3428), 2016, v. 39, n. 1, p. 23, doi. 10.1007/s13402-015-0247-3
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The small non-coding RNA response to virus infection in the Leishmania vector Lutzomyia longipalpis.
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- PLoS Neglected Tropical Diseases, 2018, v. 12, n. 6, p. 1, doi. 10.1371/journal.pntd.0006569
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Endowing plants with tolerance to virus infection by their preliminary treatment with short interfering RNAs.
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- Russian Journal of Plant Physiology, 2017, v. 64, n. 6, p. 939, doi. 10.1134/S1021443717060103
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Silencing human genetic diseases with oligonucleotide-based therapies.
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- Human Genetics, 2013, v. 132, n. 5, p. 481, doi. 10.1007/s00439-013-1288-1
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RNA interference-based therapeutics for inherited long QT syndrome (Review).
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- Experimental & Therapeutic Medicine, 2015, v. 10, n. 2, p. 395, doi. 10.3892/etm.2015.2573
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Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.
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- Pharmacogenomics & Personalized Medicine, 2017, v. 10, p. 267, doi. 10.2147/PGPM.S87945
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Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.
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- Bioscience Reports, 2014, v. 34, n. 2, p. 93, doi. 10.1042/BSR20140010
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RNA Interference-A Silent but an Efficient Therapeutic Tool.
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- Applied Biochemistry & Biotechnology, 2013, v. 169, n. 6, p. 1774, doi. 10.1007/s12010-013-0098-1
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RNA Interference: Molecular mechanism and milestone therapeutic applications.
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- Journal of Cell & Molecular Biology, 2014, v. 12, n. 1/2, p. 11
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Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer.
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- Molecular & Cellular Biochemistry, 2015, v. 398, n. 1/2, p. 11, doi. 10.1007/s11010-014-2200-6
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Technology: Investment suggests RNAi is on the up.
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- Nature, 2014, v. 510, n. 7503, p. 35, doi. 10.1038/510035b
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RNA interference rebooted.
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- Nature, 2014, v. 508, n. 7497, p. 443, doi. 10.1038/508443a
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Nanotechnology: RNAi-based nanoparticles zap glioblastoma.
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- Nature Reviews Drug Discovery, 2014, v. 13, n. 1, p. 20, doi. 10.1038/nrd4214
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- Article
Gene silencing in tick cell lines using small interfering or long double-stranded RNA.
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- Experimental & Applied Acarology, 2013, v. 59, n. 3, p. 319, doi. 10.1007/s10493-012-9598-x
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The impact of HIV-1 genetic diversity on the efficacy of a combinatorial RNAi-based gene therapy.
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- Gene Therapy, 2015, v. 22, n. 6, p. 485, doi. 10.1038/gt.2015.11
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Silencing the FOP gene.
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- Gene Therapy, 2012, v. 19, n. 7, p. 701, doi. 10.1038/gt.2011.190
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Disease-causing allele-specific silencing against the ALK2 mutants, R206H and G356D, in fibrodysplasia ossificans progressiva.
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- Gene Therapy, 2012, v. 19, n. 7, p. 781, doi. 10.1038/gt.2011.193
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SNHG8 is identified as a key regulator in non-small-cell lung cancer progression sponging to miR-542-3p by targeting CCND1/CDK6.
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- OncoTargets & Therapy, 2018, v. 11, p. 6081, doi. 10.2147/OTT.S170482
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Ultrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors.
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- OncoTargets & Therapy, 2015, v. 8, p. 3539, doi. 10.2147/OTT.S94800
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Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo.
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- Gastroenterology Research & Practice, 2013, p. 1, doi. 10.1155/2013/685150
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CD22ΔE12 as a molecular target for RNAi therapy.
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- British Journal of Haematology, 2015, v. 169, n. 3, p. 401, doi. 10.1111/bjh.13306
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Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab.
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- BMC Medicine, 2012, v. 10, n. 1, p. 28, doi. 10.1186/1741-7015-10-28
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RNA interference technology with emphasis on delivery vehicles—prospects and limitations.
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- Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 6, p. 1391, doi. 10.3109/21691401.2015.1058808
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Down-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells.
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- Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 5, p. 1201, doi. 10.3109/21691401.2015.1029628
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Antiapoptotic Bcl-2 protein as a potential target for cancer therapy: A mini review.
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- Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 5, p. 1212, doi. 10.3109/21691401.2015.1019668
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The antisense 5' end of the V2 gene confers enhanced resistance against the monopartite begomovirus cotton leaf curl Kokhran virus-Burewala strain.
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- Acta Virologica, 2019, v. 63, n. 1, p. 26, doi. 10.4149/av_2019_101
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A Mutation-Independent Therapeutic Strategy for Dominant Dystrophic Epidermolysis Bullosa.
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- Journal of Investigative Dermatology, 2013, v. 133, n. 12, p. 2793, doi. 10.1038/jid.2013.241
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Silencing of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human lung cancer cells.
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- Oncology Letters, 2016, v. 11, n. 6, p. 3735, doi. 10.3892/ol.2016.4451
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Combined RNAi targeting human Stat3 and ADAM9 as gene therapy for non-small cell lung cancer.
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- Oncology Letters, 2016, v. 11, n. 2, p. 1242, doi. 10.3892/ol.2015.4018
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Oncolytic adenovirus-expressed RNA interference of O<sup>6</sup>-methylguanine DNA methyltransferase activity may enhance the antitumor effects of temozolomide.
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- Oncology Letters, 2014, v. 8, n. 5, p. 2201, doi. 10.3892/ol.2014.2442
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The Utilization of RNA Silencing Technology to Mitigate the Voriconazole Resistance of Aspergillus Flavus; Lipofectamine-Based Delivery.
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- Advanced Pharmaceutical Bulletin, 2017, v. 7, n. 1, p. 53, doi. 10.15171/apb.2017.007
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EpCAM-targeted liposomal si-RNA delivery for treatment of epithelial cancer.
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- Drug Delivery, 2016, v. 23, n. 4, p. 1101, doi. 10.3109/10717544.2014.973082
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Special Issue: Gene Therapy with Emphasis on RNA Interference.
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- Viruses (1999-4915), 2015, v. 7, n. 8, p. 4482, doi. 10.3390/v7082830
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Insight into Alternative Approaches for Control of Avian Influenza in Poultry, with Emphasis on Highly Pathogenic H5N1.
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- Viruses (1999-4915), 2012, v. 4, n. 11, p. 3179, doi. 10.3390/v4113179
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SYNTHESIS AND CHARACTERIZATION OF GRP78 SIRNAS FOR SILENCING GENE EXPRESSION IN HEPG2 LIVER CARCINOMA CELLS.
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- Bulletin: New Jersey Academy of Science, 2014, v. 59, n. 1, p. 1
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Vertically integrated translational studies of PDX1 as a therapeutic target for pancreatic cancer via a novel bifunctional RNAi platform.
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- Cancer Gene Therapy, 2014, v. 21, n. 2, p. 48, doi. 10.1038/cgt.2013.84
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ZFX regulates glioma cell proliferation and survival in vitro and in vivo.
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- Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 17, doi. 10.1007/s11060-012-1032-z
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Knockdown of RLIP76 expression by RNA interference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells.
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- Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 73, doi. 10.1007/s11060-013-1045-2
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Recombinant AAV as a Platform for Translating the Therapeutic Potential of RNA Interference.
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- Molecular Therapy, 2014, v. 22, n. 4, p. 692, doi. 10.1038/mt.2013.285
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Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection.
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- Molecular Therapy, 2013, v. 21, n. 5, p. 973, doi. 10.1038/mt.2013.31
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Therapeutic Effects of MicroRNA-582-5p and -3p on the Inhibition of Bladder Cancer Progression.
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- Molecular Therapy, 2013, v. 21, n. 3, p. 610, doi. 10.1038/mt.2012.269
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Novel Protein Transduction Domain Mimics as Nonviral Delivery Vectors for siRNA Targeting NOTCH1 in Primary Human T cells.
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- Molecular Therapy, 2013, v. 21, n. 1, p. 201, doi. 10.1038/mt.2012.209
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Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine.
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- Polymers (20734360), 2018, v. 10, n. 9, p. 953, doi. 10.3390/polym10090953
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The emerging role of epigenetics in pulmonary arterial hypertension: an important avenue for clinical trials (2015 Grover Conference Series).
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- Pulmonary Circulation, 2016, v. 6, n. 3, p. 274, doi. 10.1086/687765
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Medical applications of RNA interference (RNAi).
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- BMC Proceedings, 2013, v. 7, n. Suppl 2, p. 1, doi. 10.1186/1753-6561-7-S2-K21
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Comparative Transcriptome Analyses Uncover Key Candidate Genes Mediating Flight Capacity in Bactrocera dorsalis (Hendel) and Bactrocera correcta (Bezzi) (Diptera: Tephritidae).
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- International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 396, doi. 10.3390/ijms19020396
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Development of Small RNA Delivery Systems for Lung Cancer Therapy.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 3, p. 5254, doi. 10.3390/ijms16035254
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RNA–Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics.
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- Molecules, 2018, v. 23, n. 12, p. 3329, doi. 10.3390/molecules23123329
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