Works matching DE "THAPSIGARGIN"

Results: 105

Thapsigargin triggers a non-apoptotic, caspase-independent programmed cell death in basophilic leukaemia cells.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02602-w

By:

Steiner, Philip;
Melek, Korollus;
Andosch, Ancuela;
Wiesbauer, Lena;
Madlmayr, Anna;
Duggan, Michelle;
Kerschbaum, Hubert H.;
Zierler, Susanna

Publication type:

Article

High expression of active ATF6 aggravates endoplasmic reticulum stress‑induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 5, p. 6483, doi. 10.3892/mmr.2018.8658

By:

Huang, Jingyong;
Wan, Li;
Lu, Heping;
Li, Xiaoqiang

Publication type:

Article

Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication.

Published in:

Viruses (1999-4915), 2020, v. 12, n. 10, p. 1093, doi. 10.3390/v12101093

By:

Goulding, Leah V.;
Yang, Jiayun;
Jiang, Zhimin;
Zhang, Hongyu;
Lea, Daniel;
Emes, Richard D.;
Dottorini, Tania;
Pu, Juan;
Liu, Jinhua;
Chang, Kin-Chow

Publication type:

Article

Loss of Oca2 disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes.

Published in:

Pigment Cell & Melanoma Research, 2013, v. 26, n. 6, p. 826, doi. 10.1111/pcmr.12158

By:

Cheng, Tsing;
Orlow, Seth J.;
Manga, Prashiela

Publication type:

Article

Bax Regulates Neuronal Ca2+ Homeostasis.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 4, p. 1706, doi. 10.1523/JNEUROSCI.2453-14.2015

By:

D'Orsi, Beatrice;
Kilbride, Seán M.;
Gang Chen;
Alvarez, Sergio Perez;
Bonner, Helena P.;
Pfeiffer, Shona;
Plesnila, Nikolaus;
Engel, Tobias;
Henshall, David C.;
Düssmann, Heiko;
Prehn, Jochen H. M.

Publication type:

Article

CRACking the Beat of Cilia: Calcium Rocks.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2019, v. 61, n. 4, p. 410, doi. 10.1165/rcmb.2019-0072ed

By:

Wittekindt, Oliver H.

Publication type:

Article

Reticulocalbin 3 Deficiency in Alveolar Epithelium Exacerbated Bleomycin-induced Pulmonary Fibrosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2018, v. 59, n. 3, p. 320, doi. 10.1165/rcmb.2017-0347OC

By:

Jiawei Jin;
Xiaoqian Shi;
Yongchao Li;
Qianyu Zhang;
YuGuo;
Chaokun Li;
Pingping Tan;
Qiuhong Fang;
Yingmin Ma;
Ma, Runlin Z.

Publication type:

Article

βig-h3 regulates store-operated Ca2+ entry and promotes the invasion of human hepatocellular carcinoma cells.

Published in:

Cell Biology International, 2011, v. 35, n. 8, p. 811, doi. 10.1042/CBI20100916

By:

Guo, Yun-Shan;
Tang, Juan;
Chen, Bo;
Huang, Wan;
Li, Yong;
Cui, Hong-Yong;
Zhang, Xin;
Wang, Shi-Jie;
Chen, Zhi-Nan;
Jiang, Jian-Li

Publication type:

Article

What happens to the unsuccessful spermatozoa?

Published in:

Andrology, 2018, v. 6, n. 2, p. 335, doi. 10.1111/andr.12467

By:

Engel, K. M.;
Springsguth, C. H.;
Grunewald, S.

Publication type:

Article

Thapsigargin and Tunicamycin Block SARS-CoV-2 Entry into Host Cells via Differential Modulation of Unfolded Protein Response (UPR), AKT Signaling, and Apoptosis.

Published in:

Cells (2073-4409), 2024, v. 13, n. 9, p. 769, doi. 10.3390/cells13090769

By:

Al Otaibi, Abeer;
Al Shaikh Mubarak, Sindiyan;
Al Hejji, Fatimah;
Almasaud, Abdulrahman;
Al Jami, Haya;
Iqbal, Jahangir;
Al Qarni, Ali;
Harbi, Naif Khalaf Al;
Bakillah, Ahmed

Publication type:

Article

PKC-Mediated Orai1 Channel Phosphorylation Modulates Ca 2+ Signaling in HeLa Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 13, p. N.PAG, doi. 10.3390/cells11132037

By:

Martínez-Martínez, Ericka;
Sánchez-Vázquez, Víctor Hugo;
León-Aparicio, Daniel;
Sanchez-Collado, Jose;
Gallegos-Gómez, Martín-Leonardo;
Rosado, Juan A.;
Arias, Juan M.;
Guerrero-Hernández, Agustin

Publication type:

Article

Calcium Pathways in Human Neutrophils—The Extended Effects of Thapsigargin and ML-9.

Published in:

Cells (2073-4409), 2018, v. 7, n. 11, p. 204, doi. 10.3390/cells7110204

By:

Ribeiro, Daniela;
Freitas, Marisa;
Rocha, Sílvia;
Lima, José L. F. C.;
Carvalho, Félix;
Fernandes, Eduarda

Publication type:

Article

Gene Expression Profile of the Human Colorectal Carcinoma LoVo Cells Treated With Sporamin and Thapsigargin.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.621462

By:

Yang, Chun;
Chen, Si-Jia;
Chen, Bo-Wen;
Zhang, Kai-Wen;
Zhang, Jing-Jie;
Xiao, Rong;
Li, Peng-Gao

Publication type:

Article

Autophagy, a novel pathway to regulate calcium mobilization inT lymphocytes.

Published in:

Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00179

By:

Wei Jia;
Ming-Xiao He;
Ian X. McLeod;
You-Wen He

Publication type:

Article

Effect of diindolylmethane on Ca2+ homeostasis and viability in MDCK renal tubular cells.

Published in:

Human & Experimental Toxicology, 2013, v. 32, n. 4, p. 344, doi. 10.1177/0960327112462727

By:

Fang, Y-C;
Chou, C-T;
Chi, C-C;
Lin, K-L;
Li, Y-D;
Cheng, H-H;
Lu, Y-C;
Cheng, J-S;
Kuo, C-C;
Jan, C-R

Publication type:

Article

Effect of phenethyl isothiocyanate on Ca2+ movement and viability in MDCK canine renal tubular cells.

Published in:

Human & Experimental Toxicology, 2012, v. 31, n. 12, p. 1251, doi. 10.1177/0960327112446841

By:

Chen, IS;
Mok, KT;
Chou, CT;
Liu, SI;
Kuo, CC;
Hsu, SS;
Chang, HT;
Tsai, JY;
Liao, WC;
Jan, CR

Publication type:

Article

Pink1 protects cortical neurons from thapsigargin-induced oxidative stress and neuronal apoptosis.

Published in:

Bioscience Reports, 2015, v. 35, p. 1, doi. 10.1042/BSR20140104

By:

Lin Li;
Guo-ku Hu

Publication type:

Article

Store Depletion by Caffeine/Ryanodine Activates Capacitative Ca2+ Entry in Nonexcitable A549 Cells1.

Published in:

Journal of Biochemistry, 2000, v. 128, n. 2, p. 329, doi. 10.1093/oxfordjournals.jbchem.a022757

By:

Xue, Hai-Hui;
Zhao, Dong-Mei;
Suda, Takafumi;
Uchida, Chiharu;
Oda, Toshiaki;
Chida, Kingo;
Ichiyama, Arata;
Nakamnrat, Hirotoshi

Publication type:

Article

Vanadate-Sensitive Microsomal ATPases and Microsomal 45Ca2+Uptake in Tracheal Epithelial Cells1.

Published in:

Journal of Biochemistry, 1998, v. 124, n. 6, p. 1094, doi. 10.1093/oxfordjournals.jbchem.a022226

By:

Kim, Young-Kee;
Sakong, Jung;
Cho, Kwang-Hyun;
Lee, Chin Ok

Publication type:

Article

Requirement of Calcium Influx for Hydrolytic Action of Membrane Phospholipids by Cytosolic Phospholipase A2 Rather than Mitogen-Activated Protein Kinase Activation in FcεRI-Stimulated Rat Peritoneal Mast Cells1.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 6, p. 1247, doi. 10.1093/oxfordjournals.jbchem.a021548

By:

Ishimoto, Tsuyoshi;
Arisato, Kyoichi;
Sato, Takashi

Publication type:

Article

Intracellular Ca2+ Mobilization and Beta-hexosaminidase Release Are Not Influenced by 60 Hz-electromagnetic Fields (EMF) in RBL 2H3 Cells.

Published in:

Korean Journal of Physiology & Pharmacology, 2011, v. 15, n. 5, p. 313, doi. 10.4196/kjpp.2011.15.5.313

By:

Yeon Hee Hwang;
Ho Sun Song;
Hee Rae Kim;
Myoung Soo Ko;
Jae Min Jeong;
Yong Ho Kim;
Jeong Soo Ryu;
Uy Dong Sohn;
Yoon-Myoung Gimm;
Sung Ho Myung;
Sang Soo Sim

Publication type:

Article

Role of endoplasmic reticulum stress in drug-induced toxicity.

Published in:

Pharmacology Research & Perspectives, 2016, v. 4, n. 1, p. n/a, doi. 10.1002/prp2.211

By:

Foufelle, Fabienne;
Fromenty, Bernard

Publication type:

Article

High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation.

Published in:

European Journal of Immunology, 2020, v. 50, n. 12, p. 2095, doi. 10.1002/eji.202048577

By:

Zou, Huajiao;
Yang, Wenjuan;
Schwär, Gertrud;
Zhao, Renping;
Alansary, Dalia;
Yin, Deling;
Schwarz, Eva C.;
Niemeyer, Barbara A.;
Qu, Bin

Publication type:

Article

Thapsigargin—From Traditional Medicine to Anticancer Drug.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 4, doi. 10.3390/ijms22010004

By:

Jaskulska, Agata;
Janecka, Anna Ewa;
Gach-Janczak, Katarzyna

Publication type:

Article

When Isolated at Full Receptivity, in Vitro Fertilized Wheat (Triticum aestivum, L.) Egg Cells Reveal [Ca2+]cyt Oscillation of Intracellular Origin.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 12, p. 23766, doi. 10.3390/ijms151223766

By:

Pónya, Zsolt;
Corsi, Ilaria;
Hoffmann, Richárd;
Kovács, Melinda;
Dobosy, Anikó;
Kovács, Attila Zoltán;
Cresti, Mauro;
Barnabás, Beáta

Publication type:

Article

MicroRNA 200c-3p regulates autophagy via upregulation of endoplasmic reticulum stress in PC-3 cells.

Published in:

Cancer Cell International, 2018, v. 18, p. 1, doi. 10.1186/s12935-017-0500-0

By:

Sohn, Eun Jung

Publication type:

Article

The CCAAT box in the proximal SERCA2 gene promoter regulates basal and stress-induced transcription in cardiomyocytes.

Published in:

Molecular & Cellular Biochemistry, 2018, v. 442, n. 1/2, p. 19, doi. 10.1007/s11010-017-3189-4

By:

Fragoso-Medina, Jorge;
Rodriguez, Gabriela;
Zarain-Herzberg, Angel

Publication type:

Article

Identification and characterization of a kunzeaol synthase from Thapsia garganica: implications for the biosynthesis of the pharmaceutical thapsigargin.

Published in:

Biochemical Journal, 2012, v. 448, n. 2, p. 261, doi. 10.1042/BJ20120654

By:

PICKEL, Benjamin;
DREW, Damian P.;
MANCZAK, Tom;
WEITZEL, Corinna;
SIMONSEN, Henrik T.;
RO, Dae-Kyun

Publication type:

Article

Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin.

Published in:

Virulence, 2021, v. 12, n. 1, p. 2946, doi. 10.1080/21505594.2021.2006960

By:

Al-Beltagi, Sarah;
Goulding, Leah V.;
Chang, Daniel K.E.;
Mellits, Kenneth H.;
Hayes, Christopher J.;
Gershkovich, Pavel;
Coleman, Christopher M.;
Chang, Kin-Chow

Publication type:

Article

Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin.

Published in:

Virulence, 2021, v. 12, n. 1, p. 2946, doi. 10.1080/21505594.2021.2006960

By:

Al-Beltagi, Sarah;
Goulding, Leah V.;
Chang, Daniel K. E.;
Mellits, Kenneth H.;
Hayes, Christopher J.;
Gershkovich, Pavel;
Coleman, Christopher M.;
Kin-Chow Chang

Publication type:

Article

Muscarinic Acetylcholine Receptors Potentiate 5′-Adenosine Monophosphate-Activated Protein Kinase Stimulation and Glucose Uptake Triggered by Thapsigargin-Induced Store-Operated Ca2+ Entry in Human Neuroblastoma Cells.

Published in:

Neurochemical Research, 2018, v. 43, n. 2, p. 245, doi. 10.1007/s11064-017-2410-x

By:

Olianas, Maria C.;
Dedoni, Simona;
Onali, Pierluigi

Publication type:

Article

Synergistic antitumor effect of a penicillin derivative combined with thapsigargin in melanoma cells.

Published in:

Journal of Cancer Research & Clinical Oncology, 2022, v. 148, n. 12, p. 3361, doi. 10.1007/s00432-022-04129-4

By:

Bellizzi, Yanina;
Cornier, Patricia G.;
Delpiccolo, Carina M. L.;
Mata, Ernesto G.;
Blank, Viviana;
Roguin, Leonor P.

Publication type:

Article

Phlda3 regulates beta cell survival during stress.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49289-5

By:

Bensellam, Mohammed;
Chan, Jeng Yie;
Lee, Kailun;
Joglekar, Mugdha V.;
Hardikar, Anandwardhan A.;
Loudovaris, Thomas;
Thomas, Helen E.;
Jonas, Jean-Christophe;
Laybutt, D. Ross

Publication type:

Article

Albumin evokes Ca2+-induced cell oxidative stress and apoptosis through TRPM2 channel in renal collecting duct cells reduced by curcumin.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48716-x

By:

Nazıroğlu, Mustafa;
Çiğ, Bilal;
Yazğan, Yener;
Schwaerzer, Gerburg K.;
Theilig, Franziska;
Pecze, László

Publication type:

Article

Influence of external calcium and thapsigargin on the uptake of polystyrene beads by the macrophage-like cell lines U937 and MH-S.

Published in:

BMC Pharmacology & Toxicology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/2050-6511-15-16

By:

Diler, Ebru;
Schwarz, Marion;
Nickels, Ruth;
Menger, Michael D.;
Beisswenger, Christoph;
Meier, Carola;
Tschernig, Thomas

Publication type:

Article

Inhibition of PERK-dependent pro-adaptive signaling pathway as a promising approach for cancer treatment.

Published in:

Polish Journal of Surgery, 2017, v. 89, n. 3, p. 7, doi. 10.5604/01.3001.0010.1020

By:

Rozpędek, Wioletta;
Pytel, Dariusz;
Dziki, Łukasz;
Nowak, Alicja;
Dziki, Adam;
Diehl, J. Alan;
Majsterek, Ireneusz

Publication type:

Article

Oxidative stress disruption of receptor-mediated calcium signaling mechanisms.

Published in:

Journal of Biomedical Science, 2013, v. 20, n. 1, p. 1, doi. 10.1186/1423-0127-20-48

By:

Tso-Hao Tang;
Chiung-Tan Chang;
Wang, Hsiu-Jen;
Erickson, Joshua D.;
Reichard, Rhett A.;
Martin, Alexis G.;
Shannon, Erica K.;
Martin, Adam L.;
Huang, Yue-Wern;
Aronstam, Robert S.

Publication type:

Article

Effect of econazole on Ca2+ signaling in human colorectal adenocarcinoma cells.

Published in:

Turkish Journal of Biochemistry / Turk Biyokimya Dergisi, 2013, v. 38, n. 2, p. 126, doi. 10.5505/tjb.2013.08370

By:

Carrillo, Celia;
del Mar Cavia, María;
Alonso-Torre, Sara R.

Publication type:

Article

FAM134B-mediated ER-phagy alleviates endoplasmic reticulum stress of rat soleus muscle in response to acute exercise.

Published in:

General Physiology & Biophysics, 2022, v. 41, n. 1, p. 71, doi. 10.4149/gpb_2021046

By:

Songlin Jin;
Lunyu Li;
Zaifang Ren;
Junping Li;
Ruiyuan Wang;
Haili Ding

Publication type:

Article

Substrate-induced conformational changes in sarcoplasmic reticulum Ca2+-ATPase probed by surface modification using diethylpyrocarbonate with mass spectrometry

Published in:

FEBS Letters, 2012, v. 586, n. 19, p. 3172, doi. 10.1016/j.febslet.2012.06.029

By:

Narumi, Ryouhei;
Yamamoto, Taibo;
Inoue, Akio;
Arata, Toshiaki

Publication type:

Article

In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains.

Published in:

Malaria Journal, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2875-12-43

By:

Abiodun, Oyindamola O.;
Brun, Reto;
Wittlin, Sergio

Publication type:

Article

Characterization of Calcium Signals Provoked by Lysophosphatidylinositol in Human Microvascular Endothelial Cells.

Published in:

Physiological Research, 2016, v. 65, n. 1, p. 53, doi. 10.33549/physiolres.932962

By:

AL SULEIMANI, Y. M.;
HILEY, C. R.

Publication type:

Article

Spontaneous long-range calcium waves in developing butterfly wings.

Published in:

BMC Developmental Biology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12861-015-0067-8

By:

Yoshikazu Ohno;
Joji M. Otaki

Publication type:

Article

Both thapsigargin- and tunicamycin-induced endoplasmic reticulum stress increases expression of Hrd1 in IRE1-dependent fashion.

Published in:

Neurological Research, 2019, v. 41, n. 2, p. 177, doi. 10.1080/01616412.2018.1547856

By:

Dibdiakova, Katarina;
Saksonova, Simona;
Pilchova, Ivana;
Klacanova, Katarina;
Tatarkova, Zuzana;
Racay, Peter

Publication type:

Article

Kujigamberoic acid A, a carboxylic acid derivative of kujigamberol, has potent inhibitory activity against the degranulation of RBL-2H3 cells.

Published in:

Bioscience, Biotechnology & Biochemistry, 2019, v. 83, n. 7, p. 1193, doi. 10.1080/09168451.2019.1597616

By:

Takahashi, Honoka;
Shimoda, Nozomu;
Koshino, Hiroyuki;
Kimura, Ken-ichi

Publication type:

Article

Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds.

Published in:

Bioscience, Biotechnology & Biochemistry, 2013, v. 77, n. 4, p. 729, doi. 10.1271/bbb.120812

By:

SHINJO, Satoko;
MIZOTANI, Yuji;
TASHIRO, Etsu;
IMOTO, Masaya

Publication type:

Article

TRPM2 contributes to antigen-stimulated Ca influx in mucosal mast cells.

Published in:

Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 7, p. 1023, doi. 10.1007/s00424-013-1219-y

By:

Oda, Satoshi;
Uchida, Kunitoshi;
Wang, Xiaoyu;
Lee, Jaemin;
Shimada, Yutaka;
Tominaga, Makoto;
Kadowaki, Makoto

Publication type:

Article

The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors.

Published in:

Toxicological Sciences, 2019, v. 167, n. 1, p. 202, doi. 10.1093/toxsci/kfy229

By:

Searfoss, George H;
Paisley, Brianna M;
Goldstein, Keith M;
Baker, Thomas K;
Willy, Jeffrey A

Publication type:

Article

Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8- O -(12-Aminododecanoyl)-8- O -Debutanoylthapsigargin.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 12, p. 1640, doi. 10.3390/biom10121640

By:

Zimmermann, Tomáš;
Drašar, Pavel;
Rimpelová, Silvie;
Christensen, Søren Brøgger;
Khripach, Vladimir A.;
Jurášek, Michal

Publication type:

Article

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress.

Published in:

Cell Death & Differentiation, 2012, v. 19, n. 11, p. 1880, doi. 10.1038/cdd.2012.74

By:

Verfaillie, T;
Rubio, N;
Garg, A D;
Bultynck, G;
Rizzuto, R;
Decuypere, J-P;
Piette, J;
Linehan, C;
Gupta, S;
Samali, A;
Agostinis, P

Publication type:

Article