Works about TH1 cells

Results: 1282

Pidotimod alleviated experimental autoimmune encephalomyelitis by regulating the balance of splenic lymphocytes.

Published in:

BMC Immunology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12865-025-00736-1

By:

Wang, Yanping;
Zhang, Sifan;
Li, Anqi;
Zhao, Ping;
Ma, Xiaoru;
Zhang, Xiyu;
Wu, Junfeng;
Qiao, Zhixin;
Wang, Chao;
Lang, Xiujuan;
Liu, Xijun;
Sun, Bo;
Li, Hulun;
Liu, Yumei

Publication type:

Article

Age-dependent differences in type I interferon, IL-12 and pro-inflammatory cytokine production by porcine peripheral blood mononuclear cells in response to pseudorabies virus-infected cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596490

By:

Claeys, Manon S. C.;
Brabant, Simon G. A. L.;
Rosschaert, Stijn;
Van Waesberghe, Cliff;
Favoreel, Herman W.

Publication type:

Article

IL-12 mRNA-LNP promotes dermal resident memory CD4+ T cell development.

Published in:

NPJ Vaccines, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41541-025-01213-x

By:

Zabala-Peñafiel, Anabel;
Gonzalez-Lombana, Claudia;
Alameh, Mohamad-Gabriel;
Sacramento, Lais A.;
Mou, Zhirong;
Phan, Anthony T.;
Aunins, Emily A.;
Tam, Ying K.;
Uzonna, Jude E.;
Weissman, Drew;
Hunter, Christopher A.;
Scott, Phillip

Publication type:

Article

M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10858-6

By:

Tung, Nguyen Tran Canh;
Nogami, Makiko;
Iwasaki, Mami;
Yahara, Yasuhito;
Seki, Shoji;
Makino, Hiroto;
Kamei, Katsuhiko;
He, Zhongyuan;
Kawaguchi, Yoshiharu

Publication type:

Article

Recombinant IgG1 Fc-μTP-L309C Ameliorates Endogenous Rheumatoid Arthritis in the K/BxN Mouse Model by Decreasing Th1 and Th17 Cells in the Spleen, Lymph Nodes and Joint and Increasing T Regulatory Cells and IL-10 in the Joint.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4509, doi. 10.3390/jcm14134509

By:

Lewis, Bonnie J. B.;
Cen, Selena;
Almizraq, Ruqayyah J.;
Binnington, Beth;
Spirig, Rolf;
Käsermann, Fabian;
Branch, Donald R.

Publication type:

Article

Network toxicology and immune-metabolic dysregulation: linking per- and polyfluoroalkyl substances exposure to osteoarthritis pathogenesis.

Published in:

Toxicology Research, 2025, v. 14, n. 3, p. 1, doi. 10.1093/toxres/tfaf077

By:

Zhang, Qian;
Zhang, Wenqi;
Liu, Zhuchen;
Luo, Chunyu;
Han, Ning;
Cai, Weixin;
Liu, Jiaxing

Publication type:

Article

C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101830

By:

Toru Tanaka;
Naoto Sasaki;
Aga Krisnanda;
Hilman Zulkifli Amin;
Ken Ito;
Sayo Horibe;
Kazuhiko Matsuo;
Ken-ichi Hirata;
Takashi Nakayama;
Yoshiyuki Rikitake

Publication type:

Article

The potential role of cuproptosis-related genes for therapy and immunoregulation in pan-cancer.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0324389

By:

Zhou, Jianpeng;
Wang, Chuanlei;
Zhi, Yao;
Li, Jia

Publication type:

Article

T follicular helper 1 cells in blood potentially mirror salivary gland-infiltrating T cells in Sjögren's disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07008-3

By:

Abe, Saori;
Tsuboi, Hiroto;
Aoki, Hiroyasu;
Toko, Hirofumi;
Honda, Fumika;
Miki, Haruka;
Asashima, Hiromitsu;
Kondo, Yuya;
Matsumoto, Isao

Publication type:

Article

Inflammatory Arthritis and the Environment: Causes and Consequences of Spondyloarthritis.

Published in:

Journal of Personalized Medicine, 2025, v. 15, n. 6, p. 237, doi. 10.3390/jpm15060237

By:

Benucci, Maurizio;
Russo, Edda;
Li Gobbi, Francesca;
Manfredi, Mariangela;
Infantino, Maria

Publication type:

Article

An approach to the influenza chimeric subunit vaccine (3M2e-HA2-NP) provides efficient protection against lethal virus challenge.

Published in:

Biotechnology Letters, 2020, v. 42, n. 7, p. 1147, doi. 10.1007/s10529-020-02822-3

By:

Saleh, Maryam;
Nowroozi, Jamileh;
Farahmand, Behrokh;
Fotouhi, Fatemeh

Publication type:

Article

IL33 activates CD8+T and NK cells through MyD88 pathway to suppress the lung cancer cell growth in mice.

Published in:

Biotechnology Letters, 2020, v. 42, n. 7, p. 1113, doi. 10.1007/s10529-020-02815-2

By:

Xu, Longsheng;
Zheng, Ying;
Wang, Jingyu;
Xu, Yufen;
Xie, Yonghong;
Yang, Zhi-Ping

Publication type:

Article

Effects of combustible cigarettes and electronic nicotine delivery systems on immune cell‐driven inflammation: Evidences from diabetic patients and multiple low dose streptozotocin‐treated diabetic mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 9, p. 1, doi. 10.1002/jbt.23841

By:

Kastratovic, Nikolina;
Arsenijevic, Aleksandar;
Harrell, Carl Randall;
Mladenovic, Violeta;
Djukic, Aleksandar;
Volarevic, Ana;
Jovanovic, Dalibor;
Zdravkovic, Marija;
Macut, Jelica Bjekic;
Djonov, Valentin;
Volarevic, Vladislav

Publication type:

Article

Investigation of hub-shared genes and regulatory mechanisms of rheumatoid arthritis and atherosclerosis.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2241, doi. 10.1007/s10067-025-07423-x

By:

Zhao, Pei;
Yuan, Kexin;
Tang, Zhipeng;
Li, Yonghui;
Yu, Yueqing;
Gao, Wei;
Zhang, Yu;
Wang, Jie;
Li, Xinxin;
Tie, Yanqing

Publication type:

Article

Th17.1 lymphocytes: emerging players in the orchestra of immune-mediated inflammatory diseases.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 8, p. 2297, doi. 10.1007/s10067-022-06202-2

By:

Misra, Durga Prasanna;
Agarwal, Vikas

Publication type:

Article

Urticaria and angiedema-like skin reactions in a patient treated with adalimumab.

Published in:

Clinical Rheumatology, 2007, v. 26, n. 5, p. 787, doi. 10.1007/s10067-005-0197-7

By:

Nikas, S. N.;
Voulgari, P. V.;
Drosos, A. A.

Publication type:

Article

APC targeting enhances immunogenicity of a novel multistage Fc-fusion tuberculosis vaccine in mice.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 24, p. 10467, doi. 10.1007/s00253-015-6952-z

By:

Soleimanpour, Saman;
Farsiani, Hadi;
Mosavat, Arman;
Ghazvini, Kiarash;
Eydgahi, Mohammad;
Sankian, Mojtaba;
Sadeghian, Hamid;
Meshkat, Zahra;
Rezaee, Seyed

Publication type:

Article

Single-cell transcriptional responses of T cells during microsporidia infection.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07990-4

By:

Tang, Yunlin;
Cao, Lu;
Jin, Jiangyan;
Li, Tangxin;
Chen, Yebo;
Lu, Yishan;
Li, Tian;
Weiss, Louis M.;
Pan, Guoqing;
Bao, Jialing;
Zhou, Zeyang

Publication type:

Article

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.

Published in:

Nature Immunology, 2010, v. 11, n. 11, p. 1057, doi. 10.1038/ni.1945

By:

Stittrich, Anna-Barbara;
Haftmann, Claudia;
Sgouroudis, Evridiki;
Kühl, Anja Andrea;
Hegazy, Ahmed Nabil;
Panse, Isabel;
Riedel, Rene;
Flossdorf, Michael;
Dong, Jun;
Fuhrmann, Franziska;
Heinz, Gitta Anne;
Fang, Zhuo;
Li, Na;
Bissels, Ute;
Hatam, Farahnaz;
Jahn, Angelina;
Hammoud, Ben;
Matz, Mareen;
Schulze, Felix-Michael;
Baumgrass, Ria

Publication type:

Article

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells.

Published in:

Nature Immunology, 2010, v. 11, n. 9, p. 862, doi. 10.1038/ni.1917

By:

Cardone, John;
Le Friec, Gaelle;
Vantourout, Pierre;
Roberts, Andrew;
Fuchs, Anja;
Jackson, Ian;
Suddason, Tesha;
Lord, Graham;
Atkinson, John P;
Cope, Andrew;
Hayday, Adrian;
Kemper, Claudia

Publication type:

Article

Increased plasticity of non-classic Thl cells toward the Th17 phenotype.

Published in:

Modern Rheumatology, 2020, v. 30, n. 5, p. 930, doi. 10.1080/14397595.2019.1667473

By:

Leipe, Jan;
Pirronello, Fausto;
Klose, Antonia;
Schulze-Koops, Hendrik;
Skapenko, Alla

Publication type:

Article

CPT-11 mitigates autoimmune diseases by suppressing effector T cells without affecting long-term anti-tumor immunity.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01983-8

By:

Liang, Hantian;
Fan, Xinzou;
Cheng, Hao;
Ma, Xiao;
Sun, Yutong;
Nan, Fang;
Zhou, Jingyang;
Shu, Panyin;
Zhang, Wei;
Zuo, Fengqiong;
Nakatsukasa, Hiroko;
Zhang, Dunfang

Publication type:

Article

Assessment of Corneal Graft Outcomes in a Murine Model of Endothelial Keratoplasty.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 17, p. 5010, doi. 10.3390/jcm13175010

By:

Narimatsu, Akitomo;
Singh, Rohan Bir;
Surico, Pier Luigi;
Lee, Seokjoo;
Forouzanfar, Katayoon;
Kahale, Francesca;
Musayeva, Aytan;
Dohlman, Thomas H.;
Blanco, Tomas;
Dana, Reza

Publication type:

Article

Pleiotropic Effects of Vitamin D in Patients with Inflammatory Bowel Diseases.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 19, p. 5715, doi. 10.3390/jcm11195715

By:

Szymczak-Tomczak, Aleksandra;
Ratajczak, Alicja Ewa;
Kaczmarek-Ryś, Marta;
Hryhorowicz, Szymon;
Rychter, Anna Maria;
Zawada, Agnieszka;
Słomski, Ryszard;
Dobrowolska, Agnieszka;
Krela-Kaźmierczak, Iwona

Publication type:

Article

Imaging Activated-T-Lymphocytes in the Salivary Glands of Patients with Sjögren's Syndrome by 99m Tc-Interleukin-2: Diagnostic and Therapeutic Implications.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 15, p. 4368, doi. 10.3390/jcm11154368

By:

Campagna, Giuseppe;
Anzola, Luz Kelly;
Varani, Michela;
Lauri, Chiara;
Gentiloni Silveri, Guido;
Chiurchioni, Lorenzo;
Spinelli, Francesca Romana;
Priori, Roberta;
Conti, Fabrizio;
Signore, Alberto

Publication type:

Article

The Role of Skin Immune System in Acne.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 6, p. 1579, doi. 10.3390/jcm11061579

By:

Firlej, Ewelina;
Kowalska, Wioleta;
Szymaszek, Karolina;
Roliński, Jacek;
Bartosińska, Joanna

Publication type:

Article

Peripheral Blood Lymphocyte Subpopulations in Patients Following Small Diameter Metal-On-Metal Total Hip Replacement at Long-Term Follow-Up.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 9, p. 2877, doi. 10.3390/jcm9092877

By:

Reiner, Tobias;
Haubenreisser, Hester;
Tripel, Elena;
Rosshirt, Nils;
Sorbi, Reza;
Nees, Timo Albert;
Gotterbarm, Tobias;
Merle, Christian;
Moradi, Babak;
Hagmann, Sébastien

Publication type:

Article

Differential Th Cell-Related Immune Responses in Young Physically Active Men after an Endurance Effort.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 6, p. 1795, doi. 10.3390/jcm9061795

By:

Kostrzewa-Nowak, Dorota;
Nowak, Robert

Publication type:

Article

Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 241, doi. 10.3390/jcm9010241

By:

Sava, Ruxandra I.;
Pepine, Carl J.;
March, Keith L.

Publication type:

Article

Immune-Inflammatory Responses in Atherosclerosis: The Role of Myeloid Cells.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1798, doi. 10.3390/jcm8111798

By:

Chistiakov, Dimitry A.;
Kashirskikh, Dmitry A.;
Khotina, Victoriya A.;
Grechko, Andrey V.;
Orekhov, Alexander N.

Publication type:

Article

STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases.

Published in:

International Reviews of Immunology, 2024, v. 43, n. 6, p. 394, doi. 10.1080/08830185.2024.2395274

By:

Tolomeo, Manlio;
Cascio, Antonio

Publication type:

Article

Synergy between Th1 and Th2 responses during Mycobacterium tuberculosis infection: A review of current understanding.

Published in:

International Reviews of Immunology, 2019, v. 38, n. 4, p. 172, doi. 10.1080/08830185.2019.1632842

By:

Abebe, Fekadu

Publication type:

Article

Comprehensive Analysis Reveals PTK6 as a Prognostic Biomarker Involved in the Immunosuppressive Microenvironment in Breast Cancer.

Published in:

2022

By:

Wang, Lili;
Luo, Shuimei;
Wang, Ziming;
Huang, Yiqiang;
Luo, Yang;
Xie, Xianhe

Publication type:

journal article

Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren's Syndrome.

Published in:

2022

By:

Fu, Jiayao;
Pu, Yiping;
Wang, Baoli;
Li, Hui;
Yang, Xiujuan;
Xie, Lisong;
Shi, Huan;
Wang, Zhijun;
Yin, Junhao;
Zhan, Tianle;
Shao, Yanxiong;
Chen, Changyu;
Luo, Qi;
Xu, Jiabao;
Zong, Zirui;
Wei, Xindi;
Xiao, Wanwen;
Yu, Chuangqi;
Zheng, Lingyan

Publication type:

journal article

Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren's Syndrome.

Published in:

Journal of Immunology Research, 2022, p. 1, doi. 10.1155/2022/3210200

By:

Fu, Jiayao;
Pu, Yiping;
Wang, Baoli;
Li, Hui;
Yang, Xiujuan;
Xie, Lisong;
Shi, Huan;
Wang, Zhijun;
Yin, Junhao;
Zhan, Tianle;
Shao, Yanxiong;
Chen, Changyu;
Luo, Qi;
Xu, Jiabao;
Zong, Zirui;
Wei, Xindi;
Xiao, Wanwen;
Yu, Chuangqi;
Zheng, Lingyan

Publication type:

Article

DDA/TDB liposomes containing soluble Leishmania major antigens induced a mixed Th1/Th2 immune response in BALB/c mice.

Published in:

Nanomedicine Journal, 2017, v. 4, n. 2, p. 71, doi. 10.22038/nmj.2017.21754.1234

By:

Hojatizade, Mansure;
Badiee, Ali;
Khamesipour, Ali;
Mirshafiey, Abbas;
Akhtari, Javad;
Mehravaran, Ahmad;
Alavizadeh, Seyedeh Hoda;
Abbasi, Azam;
Saberi, Zahra;
Nikpoor, Amin Reza;
Jaafari, Mahmoud Reza

Publication type:

Article

High content imaging shows distinct macrophage and dendritic cell phenotypes for psoriasis and atopic dermatitis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99727-w

By:

Behr, Nathalie J.;
Pierre, Sandra;
Ickelsheimer, Tanja;
Ziegler, Nicole;
Luckhardt, Sonja;
Kannt, Aimo;
Pinter, Andreas;
Geisslinger, Gerd;
Schäfer, Stephan M. G.;
König, Anke;
Scholich, Klaus

Publication type:

Article

Unique Macrophages Different from M1/M2 Macrophages Inhibit T Cell Mitogenesis while Upregulating Th17 Polarization.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04146

By:

Yutaka Tatano;
Toshiaki Shimizu;
Haruaki Tomioka

Publication type:

Article

Identification of benzo(a)pyrene-related toxicological targets and their role in chronic obstructive pulmonary disease pathogenesis: a comprehensive bioinformatics and machine learning approach.

Published in:

BMC Pharmacology & Toxicology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s40360-025-00842-1

By:

Deng, Jiehua;
Wei, Lixia;
Chen, Yongyu;
Li, Xiaofeng;
Zhang, Hui;
Wei, Xuan;
Feng, Xin;
Qiu, Xue;
Liang, Bin;
Zhang, Jianquan

Publication type:

Article

Elucidating common pathogenic transcriptional networks in infective endocarditis and sepsis: integrated insights from biomarker discovery and single-cell RNA sequencing.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1298041

By:

Chen Yi;
Haoxiang Zhang;
Jun Yang;
Dongjuan Chen;
Shaofeng Jiang

Publication type:

Article

Th1-related transcription factors and cytokines in systemic lupus erythematosus.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1305590

By:

Yang-Yang Tang;
Da-Cheng Wang;
You-Yue Chen;
Wang-Dong Xu;
An-Fang Huang

Publication type:

Article

Escherichia coli adhesion protein FimH exacerbates colitis via CD11b+CD103- dendritic cell activation.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1284770

By:

Wei Zhang;
Eun-Koung An;
So-Jung Kim;
Hae-Bin Park;
Lee, Peter C. W.;
Jun-O Jin

Publication type:

Article

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4+ T cells.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1193535

By:

Sandoval, Simone;
Malany, Keegan;
Thongphanh, Krista;
Martinez, Clarisa A.;
Goodson, Michael L.;
Da Costa Souza, Felipe;
Lo-Wei Lin;
Sweeney, Nicolle;
Pennington, Jamie;
Lein, Pamela J.;
Kerkvliet, Nancy I.;
Ehrlich, Allison K.

Publication type:

Article

Corrigendum: Transcriptional inhibition of STAT1 functions in the nucleus alleviates Th1 and Th17 cell-mediated inflammatory diseases.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1307575

By:

Jiyoon Park;
Min-Ji Son;
Chun-Chang Ho;
Su-Hyeon Lee;
Yuna Kim;
Jaekyeung An;
Sang-Kyou Lee

Publication type:

Article

Transcriptional inhibition of STAT1 functions in the nucleus alleviates Th1 and Th17 cellmediated inflammatory diseases.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2022.1054472

By:

Jiyoon Park;
Min-Ji Son;
Chun-Chang Ho;
Su-Hyeon Lee;
Yuna Kim;
Jaekyeung An;
Sang-Kyou Lee

Publication type:

Article

Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1223539

By:

Llorca, Tatiana;
Ruiz-Magaña, Maria Jose;
Martinez-Aguilar, Rocio;
García-Valdeavero, Olga María;
Rodríguez-Doña, Lucia;
Abadia-Molina, Ana Clara;
Ruiz-Ruiz, Carmen;
Olivares, Enrique G.

Publication type:

Article

A novel trivalent non-Fc anti-CD3 Collabody preferentially induces Th1 cell apoptosis in vitro and long-lasting remission in recent-onset diabetic NOD mice.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1201853

By:

Chuan-Chuan Huang;
Hsiang-Hsuan Sung;
Hsiu-Chuan Li;
Shi-Chuen Miaw;
Kung, John T.;
Min-Yuan Chou;
Wu-Hsieh, Betty A.

Publication type:

Article

Recombinant proteins A29L, M1R, A35R, and B6R vaccination protects mice from mpox virus challenge.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1203410

By:

Ding Tang;
Xiaoke Liu;
Jia Lu;
Huifen Fan;
Xiuli Xu;
Kaili Sun;
Ruyu Wang;
Chunyang Li;
Demiao Dan;
Hongqiao Du;
Zejun Wang;
Xinguo Li;
Xiaoming Yang

Publication type:

Article

Glycan dependent phenotype differences of HIV-1 generated from macrophage versus CD4+ T helper cell populations.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1107349

By:

Heeregrave, Edwin J.;
Thomas, Jordan;
van Capel, Toni M.;
de Jong, Esther C.;
Pollakis, Georgios;
Paxton, William A.

Publication type:

Article

Exploring the role of T helper subgroups and their cytokines in the development of pregnancy-induced hypertension.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1126784

By:

Qianqian Zhou;
Youcheng Wu;
Dongmei Zhang

Publication type:

Article