Works matching DE "TETRAHYDROFOLATE dehydrogenase"
Results: 508
Preclinical Evaluation of Selene-Ethylenelacticamides in Tuberculosis: Effects Against Active, Dormant, and Resistant Mycobacterium Tuberculosis and In Vitro Toxicity Investigation.
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- Microorganisms, 2025, v. 13, n. 2, p. 396, doi. 10.3390/microorganisms13020396
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Synthesis, Antimicrobial Activities, and Model of Action of Indolyl Derivatives Containing Amino-Guanidinium Moieties.
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- Molecules, 2025, v. 30, n. 4, p. 887, doi. 10.3390/molecules30040887
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Ultralight Ultrafast Enzymes.
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- Angewandte Chemie, 2024, v. 136, n. 3, p. 1, doi. 10.1002/ange.202316488
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Third‐Generation Covalent TMP‐Tag for Fast Labeling and Multiplexed Imaging of Cellular Proteins.
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- Angewandte Chemie, 2022, v. 134, n. 36, p. 1, doi. 10.1002/ange.202207905
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Drug Repurposing by Siderophore Conjugation: Synthesis and Biological Evaluation of Siderophore‐Methotrexate Conjugates as Antibiotics.
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- Angewandte Chemie, 2022, v. 134, n. 36, p. 1, doi. 10.1002/ange.202204139
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Effect of the structural characteristics of dihydrofolate reductase inhibitors on their metabolic properties.
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- Journal of Structural Chemistry, 2012, v. 53, n. 2, p. 365, doi. 10.1134/S0022476612020230
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MODELING OF NEW POTENTIAL INHIBITORS OF DIHYDROFOLATE REDUCTASE BASED ON 1,3,4-TH I AD I AZ OLE AMIDOALKYL DERIVATIVES.
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- Issues of Chemistry & Chemical Technology / Voprosy Khimii & Khimicheskoi Tekhnologii, 2023, n. 5, p. 91, doi. 10.32434/0321-4095-2023-150-5-91-97
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The aminosalicylate - folate connection.
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- Drug Metabolism Reviews, 2024, v. 56, n. 1, p. 80, doi. 10.1080/03602532.2024.2303507
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Study of local intracellular signals regulating axonal morphogenesis using a microfluidic device.
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- Science & Technology of Advanced Materials, 2016, v. 17, n. 1, p. 691, doi. 10.1080/14686996.2016.1241131
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A novel bicyclic 2,4-diaminopyrimidine inhibitor of Streptococcus suis dihydrofolate reductase.
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- PeerJ, 2021, p. 1, doi. 10.7717/peerj.10743
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Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 203, doi. 10.1080/14756366.2022.2142786
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Discovery of new non-pyrimidine scaffolds as Plasmodium falciparum DHFR inhibitors by fragment-based screening.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 198, doi. 10.1080/14756366.2020.1854244
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Design, synthesis and evaluation of carbazole derivatives as potential antimicrobial agents.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 296, doi. 10.1080/14756366.2020.1850713
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Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and insilico studies.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1491, doi. 10.1080/14756366.2020.1791842
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Sulfa and trimethoprim-like drugs - antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2014, v. 29, n. 3, p. 379, doi. 10.3109/14756366.2013.787422
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Synthesis and biological screening of some pyridine derivatives as anti-malarial agents.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2012, v. 27, n. 1, p. 69, doi. 10.3109/14756366.2011.575071
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MTHFD1 polymorphism as maternal risk for neural tube defects: a meta-analysis.
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- Neurological Sciences, 2015, v. 36, n. 4, p. 607, doi. 10.1007/s10072-014-2035-7
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The Prevalence of SNP rs12517451 in Gene Transcribing Dihydrofolate Reductase and Drug Adverse Effects among MTXtreated Rheumatoid Arthritis Patients in Kelantan, Malaysia.
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- Malaysian Journal of Medicine & Health Sciences, 2021, n. 3, p. 98
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Synthesis and structural insights of bis(2-methoxy-6-{[(2-methylpropyl)imino]methyl}phenolato) nickel (II) complex through DFT and docking investigations.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-85465-6
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Synthesis, characterization, quantum chemical modelling, molecular docking, in silico and in vitro assessment of 3-(2-bromo-5-fluorophenyl))-1-(thiophen-2-yl)prop-2-en-1-one.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-79747-8
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Prevalence of molecular markers of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from West Africa during 2012–2022.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-75828-w
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Evolution of Pfdhps and Pfdhfr mutations before and after adopting seasonal malaria chemoprevention in Nanoro, Burkina Faso.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-75369-2
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Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer.
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- Biomolecules (2218-273X), 2024, v. 14, n. 11, p. 1454, doi. 10.3390/biom14111454
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NAD- and NADPH-Contributing Enzymes as Therapeutic Targets in Cancer: An Overview.
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- Biomolecules (2218-273X), 2020, v. 10, n. 3, p. 358, doi. 10.3390/biom10030358
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Characterization of Phenotypic and Genotypic Diversity of Stenotrophomonas maltophilia Strains Isolated From Selected Hospitals in Iran.
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- Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.01191
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Plasmodium falciparum DHFR and DHPS Mutations Are Associated With HIV-1 Co-Infection and a Novel DHPS Mutation I504T Is Identified in Western Kenya.
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- Frontiers in Cellular & Infection Microbiology, 2020, p. N.PAG, doi. 10.3389/fcimb.2020.600112
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Preliminary Evaluation of Recombinant EPC1 and TPx for Serological Diagnosis of Animal Cystic Echinococcosis.
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- Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. 1, doi. 10.3389/fcimb.2020.00177
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Chalcone analogue as potent anti-malarial compounds against Plasmodium falciparum: Synthesis, biological evaluation, and docking simulation study.
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- Asian Pacific Journal of Tropical Biomedicine, 2017, v. 7, n. 8, p. 675, doi. 10.1016/j.apjtb.2017.07.004
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The Design and Optimisation of Novel Human Dihydrofolate Reductase Inhibitors for the Management of Proliferative Disease.
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- Biomirror, 2015, v. 6, n. 9, p. 92
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Barrier crossing in dihydrofolate reductase does not involve a rate-promoting vibration.
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- Molecular Physics, 2012, v. 110, n. 9/10, p. 531, doi. 10.1080/00268976.2012.655337
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Identification and functional characterization of type II toxin/antitoxin systems in Aggregatibacter actinomycetemcomitans.
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- 2018
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- journal article
High-level expression of biologically active human follicle stimulating hormone in the Chinese hamster ovary cell line by a pair of tricistronic and monocistronic vectors.
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- PLoS ONE, 2019, v. 14, n. 7, p. 1, doi. 10.1371/journal.pone.0219434
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Molecular detection of DHFR gene polymorphisms in Pneumocystis jirovecii isolates from Indian patients.
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- Journal of Infection in Developing Countries, 2015, v. 9, n. 11, p. 1250, doi. 10.3855/jidc.6810
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The Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Reveals a Novel Architecture for the Bifunctional Enzyme.
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- Journal of Eukaryotic Microbiology, 2003, v. 50, p. 555, doi. 10.1111/j.1550-7408.2003.tb00627.x
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Pneumocystis jirovecii Dihydrofolate Reductase Polymorphisms Associated with Failure of Prophylaxis.
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- Journal of Eukaryotic Microbiology, 2003, v. 50, p. 656, doi. 10.1111/j.1550-7408.2003.tb00673.x
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Decreased Susceptibility to Dihydrofolate Reductase Inhibitors Associated With Genetic Polymorphisms in Ugandan Plasmodium falciparum Isolates.
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- 2022
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- journal article
Prevalence of Antimalarial Resistance Mediators.
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- 2021
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- journal article
Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda.
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- 2021
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- journal article
Assessment of genetic polymorphisms associated with malaria antifolate resistance among the population of Libreville, Gabon.
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- Malaria Journal, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12936-023-04615-1
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Artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Liberia: in vivo efficacy and frequency of molecular markers.
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- Malaria Journal, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12936-022-04140-7
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Dihydrofolate reductase, thymidylate synthase, and serine hydroxy methyltransferase: successful targets against some infectious diseases.
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- Molecular Biology Reports, 2022, v. 49, n. 7, p. 6659, doi. 10.1007/s11033-022-07266-8
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Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine.
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- Molecular Medicine, 2018, v. 24, n. 1, p. 1, doi. 10.1186/s10020-018-0010-0
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A <italic>Helicobacter pylori</italic> Vacuolating Cytotoxin A: Mouse DHFR Fusion Protein Triggers Dye Release from Liposomes.
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- Current Microbiology, 2018, v. 75, n. 2, p. 223, doi. 10.1007/s00284-017-1369-9
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Structural Diversity of Class 1 Integrons in Multiresistant Strains of Escherichia coli Isolated from Patients in a Hospital in Mexico City.
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- Current Microbiology, 2015, v. 71, n. 4, p. 501, doi. 10.1007/s00284-015-0876-9
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A dual fluorescent Plasmodium cynomolgi reporter line reveals in vitro malaria hypnozoite reactivation.
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- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-019-0737-3
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The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
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- Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0236-y
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Taurine and enzymatically modified isoquercitrin protected against methotrexate‐induced deteriorations in the conductivity and rhythmicity of the heart in rats: Antioxidant, anti‐inflammatory, and histological architecture approach.
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- Journal of Applied Toxicology, 2024, v. 44, n. 12, p. 1924, doi. 10.1002/jat.4682
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Adaptations for pressure and temperature effects on loop motion in Escherichia coli and Moritella profunda dihydrofolate reductase.
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- High Pressure Research, 2019, v. 39, n. 2, p. 225, doi. 10.1080/08957959.2019.1584799
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Benzamide Trimethoprim Derivatives as Human Dihydrofolate Reductase Inhibitors—Molecular Modeling and In Vitro Activity Study.
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- Biomedicines, 2024, v. 12, n. 5, p. 1079, doi. 10.3390/biomedicines12051079
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Phytochemical Analyses, Antimicrobial Activities and Possible Antimicrobial Mechanism of Adansonia Digitata: An Animal Model.
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- Alexandria Journal of Veterinary Sciences, 2022, v. 74, n. 2, p. 50, doi. 10.5455/ajvs.50029
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