Works about TACRINE

Results: 249

Evaluation of anti-amnesic effect of Conyza bonariensis in rats.

Published in:

Indian Journal of Pharmacology, 2022, v. 54, n. 2, p. 102, doi. 10.4103/ijp.ijp_201_19

By:

Saikia, Beenita;
Buragohain, Lipika;
Barua, Chandana;
Sarma, Jadav;
Tamuli, Sarojini;
Kalita, Dhruba;
Barua, Acheenta;
Barua, Iswar;
Elancheran, Ramakrishna

Publication type:

Article

Effects of Anti-Alzheimer Drugs on Phosphorylation and Assembly of Microtubules from Brain Microtubular Proteins.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 156, n. 6, p. 768, doi. 10.1007/s10517-014-2445-9

By:

Shevtsov, P.;
Shevtsova, E.;
Burbaeva, G.;
Bachurin, S.

Publication type:

Article

In-vitro stability and metabolism of a tacrine-silibinin codrug.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 12, p. 1765, doi. 10.1111/jphp.12070

By:

Zenger, Katharina;
Chen, Xinyu;
Decker, Michael;
Kraus, Birgit

Publication type:

Article

Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for 'Alzheimer's disease: an in silico approach.

Published in:

BMC Molecular & Cell Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12860-021-00386-2

By:

Bakare, Olalekan Olanrewaju;
Fadaka, Adewale Oluwaseun;
Akanbi, Musa Oyebowale;
Akinyede, Kolajo Adedamola;
Klein, Ashwil;
Keyster, Marshall

Publication type:

Article

Study on the Effect of Phaseolus vulgaris Methanol Extract on Haloperidol and Tacrine Induced Parkinsonism.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2022, v. 56, n. 3, p. 804, doi. 10.5530/ijper.56.3.131

By:

Kaur, Balvinder;
Saxena, Jyoti

Publication type:

Article

SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2019, v. 53, n. 2, p. 268, doi. 10.5530/ijper.53.2.35

By:

Ökten, Salih;
Ekiz, Makbule;
Tutar, Ahmet;
Bütün, Burcu;
Koçyiğit, Ümit Muhammet;
Topçu, Gülaçtı;
Gülçin, İlhami

Publication type:

Article

Design, Synthesis, Biological Activity, and Molecular Modeling of Novel Spiroquinazoline Derivatives as Acetylcholinesterase Inhibitors for Alzheimer Disease.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 9, p. 8082, doi. 10.1080/10406638.2022.2144911

By:

Shtaiwi, Majed;
Aljaar, Nayyef;
Al-Najjar, Lana;
Malakar, Chandi C.;
Shtaiwi, Amneh;
Abu-Sini, Mohammad;
Al-Refai, Mahmoud

Publication type:

Article

Two new alkaloids from the twigs of <italic>Trigonostemon filipes</italic>.

Published in:

Journal of Asian Natural Products Research, 2018, v. 20, n. 3, p. 270, doi. 10.1080/10286020.2017.1332048

By:

Wang, Yu;
Wang, Pei;
Kong, Fan-Dong;
Wang, Jun;
Zuo, Wen-Jian;
Wang, Hao;
Dai, Hao-Fu;
Mei, Wen-Li

Publication type:

Article

Two new 2-(2-Hydroxy-2-phenylethyl)chromens from agarwood originating from Aquilaria crassna.

Published in:

Journal of Asian Natural Products Research, 2018, v. 20, n. 2, p. 122, doi. 10.1080/10286020.2017.1379998

By:

Wang, Hong-Ni;
Mei, Wen-Li;
Dong, Wen-Hua;
Kong, Fan-Dong;
Li, Wei;
Yuan, Jing-Zhe;
Dai, Hao-Fu

Publication type:

Article

Three new flavanoids from artificially induced dragon's blood of Dracaena cambodiana.

Published in:

Journal of Asian Natural Products Research, 2018, v. 20, n. 1, p. 55, doi. 10.1080/10286020.2017.1322583

By:

Li, Fei-Xiang;
Wang, Hui;
Gai, Cui-Juan;
Chen, Hui-Qin;
Li, Wei;
Mei, Wen-Li;
Dai, Hao-Fu

Publication type:

Article

Potential Anti-Cholinesterase Activity of Bioactive Compounds Extracted from Cassia grandis L.f. and Cassia timoriensis DC.

Published in:

Plants (2223-7747), 2023, v. 12, n. 2, p. 344, doi. 10.3390/plants12020344

By:

Alhawarri, Maram B.;
Dianita, Roza;
Rawa, Mira Syahfriena Amir;
Nogawa, Toshihiko;
Wahab, Habibah A.

Publication type:

Article

Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42239-2

By:

Soliman, Aiten M.;
Ghorab, Walid M.;
Lotfy, Dina M.;
Karam, Heba M.;
Ghorab, Mostafa M.;
Ramadan, Laila A.

Publication type:

Article

Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42239-2

By:

Soliman, Aiten M.;
Ghorab, Walid M.;
Lotfy, Dina M.;
Karam, Heba M.;
Ghorab, Mostafa M.;
Ramadan, Laila A.

Publication type:

Article

The anti-Alzheimer potential of novel spiroindolin-1,2-diazepine derivatives as targeted cholinesterase inhibitors with modified substituents.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38236-0

By:

Pourtaher, Hormoz;
Hasaninejad, Alireza;
Zare, Shahrokh;
Tanideh, Nader;
Iraji, Aida

Publication type:

Article

Design, synthesis, and pharmacological evaluation of heteroaryl thiol-linked kojic acid derivatives as a novel class of acetylcholinesterase inhibitors for Alzheimer's disease therapy.

Published in:

3 Biotech, 2025, v. 15, n. 5, p. 1, doi. 10.1007/s13205-025-04295-5

By:

Singh, Madan;
Karthikeyan, Chandrabose;
Waiker, Digambar Kumar;
Tiwari, Akhilesh;
Shrivastava, Sushant K.;
Sousa, Sérgio F.;
Kiriwan, Duangnapa;
Martins, Fábio G.;
Moorthy, Narayana Subbiah Hari Narayana

Publication type:

Article

Polymer drug conjugates containing memantine, tacrine and cinnamic acid: promising nanotherapeutics for the treatment of Alzheimer's disease.

Published in:

Journal of Microencapsulation, 2023, v. 40, n. 1, p. 15, doi. 10.1080/02652048.2023.2167011

By:

Naki, Tobeka;
Matshe, William Morwa Reagile;
Balogun, Mohammed Olusegun;
Sinha Ray, Suprakas;
Egieyeh, Samuel Ayodele;
Aderibigbe, Blessing Atim

Publication type:

Article

SAR studies of quinoline and derivatives as potential treatments for Alzheimer's disease.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 2, p. N.PAG, doi. 10.1016/j.arabjc.2022.104502

By:

Li, Zhao-Hui;
Yin, Li-Quan;
Zhao, Dong-Hai;
Jin, Lian-Hai;
Sun, Ya-Juan;
Tan, Cheng

Publication type:

Article

Exploring facile synthesis and cholinesterase inhibiting potential of heteroaryl substituted imidazole derivatives for the treatment of Alzheimer's disease.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 1, p. N.PAG, doi. 10.1016/j.arabjc.2022.104384

By:

Chaudhry, Faryal;
Munir, Rubina;
Ashraf, Muhammad;
Mehr-un-Nisa;
Huma, Rahila;
Malik, Nayab;
Hussain, Safdar;
Ali Munawar, Munawar;
Ain Khan, Misbahul

Publication type:

Article

The design of fluoroquinolone-based cholinesterase inhibitors: Synthesis, biological evaluation and in silico docking studies.

Published in:

Arabian Journal of Chemistry, 2021, v. 14, n. 7, p. N.PAG, doi. 10.1016/j.arabjc.2021.103211

By:

Mansha, Muhammad;
Taha, Muhammad;
Hassane Anouar, El;
Ullah, Nisar

Publication type:

Article

In silico study of tacrine and acetylcholine binding profile with human acetylcholinesterase: docking and electronic structure.

Published in:

Journal of Molecular Modeling, 2022, v. 28, n. 9, p. 1, doi. 10.1007/s00894-022-05252-2

By:

Nascimento, Letícia A.;
Nascimento, Érica C. M.;
Martins, João B. L.

Publication type:

Article

Structure–activity relationship of tacrine and its analogues in relation to inhibitory activity against Alzheimer's disease.

Published in:

Journal of Molecular Modeling, 2019, v. 25, n. 5, p. N.PAG, doi. 10.1007/s00894-019-3993-8

By:

Vieira, Ingrid;
Camargo, Lilian T. F. M.;
Ribeiro, Luciano;
Rodrigues, Allane C. C.;
Camargo, Ademir J.

Publication type:

Article

DRUGS TO TREAT ALZHEIMER'S DISEASE.

Published in:: Journal of Psychosocial Nursing & Mental Health Services, 2014, v. 52, n. 4, p. 57, doi. 10.3928/02793695-20140220-79
Publication type:: Article

Clip & Save: Drug Chart.

Published in:: Journal of Psychosocial Nursing & Mental Health Services, 2013, v. 51, n. 4, p. 11, doi. 10.3928/02793695-20130306-99
Publication type:: Article

Synthesis of Novel Pyrano[2,3- b]pyridines from α,α′-Bis(substituted-benzylidene)cycloalkanones.

Published in:

Journal of Heterocyclic Chemistry, 2013, v. 50, n. 3, p. 625, doi. 10.1002/jhet.1612

By:

Bigdeli, Mohammad Ali;
Marjani, Katayon;
Farokhi, Elinaz;
Sheikhhosseini, Enayatollah;
Ghazanfari, Dadkhoda

Publication type:

Article

Neuroprotective Effects of Bis(7)-tacrine in a Rat Model of Pressure-Induced Retinal Ischemia.

Published in:

Cell Biochemistry & Biophysics, 2014, v. 68, n. 2, p. 275, doi. 10.1007/s12013-013-9707-4

By:

Li, Jing-bo;
Lu, Zhi-gang;
Xu, Li;
Wang, Qi;
Zhang, Zu-hai;
Fang, Jia-hua

Publication type:

Article

Facile and simple purification method for small extracellular vesicles obtained from a culture medium through cationic particle capture.

Published in:

Analytical & Bioanalytical Chemistry, 2021, v. 413, n. 9, p. 2523, doi. 10.1007/s00216-021-03207-9

By:

Kato, Masaru;
Nakamoto, Riho;
Ishizuka, Masaki;
Watanabe, Noriko

Publication type:

Article

Multitargeted C9‐substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics.

Published in:

Drug Development Research, 2023, v. 84, n. 1, p. 121, doi. 10.1002/ddr.22017

By:

Raghuvanshi, Rinky;
Jamwal, Ashiya;
Nandi, Utpal;
Bharate, Sandip B.

Publication type:

Article

Design, synthesis, and biological evaluation of thienopyrimidine and thienotriazine derivatives as multitarget anti‐Alzheimer agents.

Published in:

Drug Development Research, 2022, v. 83, n. 6, p. 1394, doi. 10.1002/ddr.21968

By:

Eissa, Kholoud I.;
Kamel, Mona M.;
Mohamed, Lamia W.;
Galal, Mai A.;
Kassab, Asmaa E.

Publication type:

Article

Unfolding the Antibacterial Activity and Acetylcholinesterase Inhibition Potential of Benzofuran-Triazole Hybrids: Synthesis, Antibacterial, Acetylcholinesterase Inhibition, and Molecular Docking Studies.

Published in:

Molecules, 2023, v. 28, n. 16, p. 6007, doi. 10.3390/molecules28166007

By:

Saeed, Sadaf;
Zahoor, Ameer Fawad;
Kamal, Shagufta;
Raza, Zohaib;
Bhat, Mashooq Ahmad

Publication type:

Article

Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives.

Published in:

Molecules, 2023, v. 28, n. 8, p. 3357, doi. 10.3390/molecules28083357

By:

Schepetkin, Igor A.;
Nurmaganbetov, Zhangeldy S.;
Fazylov, Serik D.;
Nurkenov, Oralgazy A.;
Khlebnikov, Andrei I.;
Seilkhanov, Tulegen M.;
Kishkentaeva, Anarkul S.;
Shults, Elvira E.;
Quinn, Mark T.

Publication type:

Article

Anti-Neuroinflammatory Potential of Natural Products in the Treatment of Alzheimer's Disease.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1486, doi. 10.3390/molecules28031486

By:

Deng, Mingzhenlong;
Yan, Wanli;
Gu, Zhicheng;
Li, Yan;
Chen, Lei;
He, Bin

Publication type:

Article

Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer's Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 2, p. 559, doi. 10.3390/molecules28020559

By:

Khan, Shoaib;
Ullah, Hayat;
Taha, Muhammad;
Rahim, Fazal;
Sarfraz, Maliha;
Iqbal, Rashid;
Iqbal, Naveed;
Hussain, Rafaqat;
Ali Shah, Syed Adnan;
Ayub, Khurshid;
Albalawi, Marzough Aziz;
Abdelaziz, Mahmoud A.;
Alatawi, Fatema Suliman;
Khan, Khalid Mohammed

Publication type:

Article

Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.

Published in:

Molecules, 2023, v. 28, n. 1, p. 238, doi. 10.3390/molecules28010238

By:

Godyń, Justyna;
Zaręba, Paula;
Stary, Dorota;
Kaleta, Maria;
Kuder, Kamil J.;
Latacz, Gniewomir;
Mogilski, Szczepan;
Reiner-Link, David;
Frank, Annika;
Doroz-Płonka, Agata;
Olejarz-Maciej, Agnieszka;
Sudoł-Tałaj, Sylwia;
Nolte, Tobias;
Handzlik, Jadwiga;
Stark, Holger;
Więckowska, Anna;
Malawska, Barbara;
Kieć-Kononowicz, Katarzyna;
Łażewska, Dorota;
Bajda, Marek

Publication type:

Article

Synthesis of Novel Bromophenol with Diaryl Methanes—Determination of Their Inhibition Effects on Carbonic Anhydrase and Acetylcholinesterase.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7426, doi. 10.3390/molecules27217426

By:

Oztaskin, Necla;
Goksu, Suleyman;
Demir, Yeliz;
Maras, Ahmet;
Gulcin, İlhami

Publication type:

Article

Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Studies of Indole Based Thiadiazole Derivatives as Dual Inhibitor of Acetylcholinesterase and Butyrylchloinesterase.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7368, doi. 10.3390/molecules27217368

By:

Khan, Shoaib;
Iqbal, Shahid;
Taha, Muhammad;
Rahim, Fazal;
Shah, Mazloom;
Ullah, Hayat;
Bahadur, Ali;
Alrbyawi, Hamad;
Dera, Ayed A.;
Alahmdi, Mohammed Issa;
Pashameah, Rami Adel;
Alzahrani, Eman;
Farouk, Abd-ElAziem

Publication type:

Article

Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity.

Published in:

Molecules, 2022, v. 27, n. 19, p. 6276, doi. 10.3390/molecules27196276

By:

Titov, Alexander A.;
Purgatorio, Rosa;
Obydennik, Arina Y.;
Listratova, Anna V.;
Borisova, Tatiana N.;
de Candia, Modesto;
Catto, Marco;
Altomare, Cosimo D.;
Varlamov, Alexey V.;
Voskressensky, Leonid G.

Publication type:

Article

A Preliminary Assessment of the Nutraceutical Potential of Acai Berry (Euterpe sp.) as a Potential Natural Treatment for Alzheimer's Disease.

Published in:

Molecules, 2022, v. 27, n. 15, p. 4891, doi. 10.3390/molecules27154891

By:

ALNasser, Maryam N.;
Mellor, Ian R.;
Carter, Wayne G.

Publication type:

Article

In Vitro and In Silico Investigation of Diterpenoid Alkaloids Isolated from Delphinium chitralense.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144348

By:

Ahmad, Shujaat;
Ahmad, Manzoor;
Almehmadi, Mazen;
Shah, Syed Adnan Ali;
Khan, Farman Ali;
Khan, Nasir Mehmood;
Khan, Asifullah;
Zainab;
Halawi, Mustafa;
Ahmad, Hanif

Publication type:

Article

Design, Synthesis and Bioactivity Evaluation of Coumarin–BMT Hybrids as New Acetylcholinesterase Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 7, p. 2142, doi. 10.3390/molecules27072142

By:

Zeng, Fanxin;
Lu, Tao;
Wang, Jie;
Nie, Xuliang;
Xiong, Wanming;
Yin, Zhongping;
Peng, Dayong

Publication type:

Article

Design, Synthesis, and Evaluation of Novel 2 H -Benzo[b][1,4]thiazin-3(4 H)-one Derivatives as New Acetylcholinesterase Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 7, p. 2121, doi. 10.3390/molecules27072121

By:

Haji Ali, Sazan;
Osmaniye, Derya;
Sağlık, Begüm Nurpelin;
Levent, Serkan;
Özkay, Yusuf;
Kaplancıklı, Zafer Asım

Publication type:

Article

Alkaloids in Future Drug Discovery.

Published in:

Molecules, 2022, v. 27, n. 4, p. 1347, doi. 10.3390/molecules27041347

By:

Ferreira, Maria-José U.

Publication type:

Article

Fractionation of Lycopodiaceae Alkaloids and Evaluation of Their Anticholinesterase and Cytotoxic Activities.

Published in:

Molecules, 2021, v. 26, n. 21, p. 6379, doi. 10.3390/molecules26216379

By:

Dymek, Aleksandra;
Widelski, Jarosław;
Wojtanowski, Krzysztof Kamil;
Vivcharenko, Vladyslav;
Przekora, Agata;
Mroczek, Tomasz

Publication type:

Article

Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold.

Published in:

Molecules, 2021, v. 26, n. 16, p. 4895, doi. 10.3390/molecules26164895

By:

Suwanhom, Paptawan;
Saetang, Jirakrit;
Khongkow, Pasarat;
Nualnoi, Teerapat;
Tipmanee, Varomyalin;
Lomlim, Luelak

Publication type:

Article

Design, Synthesis, and Evaluation of Dihydropyranopyrazole Derivatives as Novel PDE2 Inhibitors for the Treatment of Alzheimer's Disease.

Published in:

Molecules, 2021, v. 26, n. 10, p. 3034, doi. 10.3390/molecules26103034

By:

Zhou, Yan;
Li, Jinjian;
Yuan, Han;
Su, Rui;
Huang, Yue;
Huang, Yiyou;
Li, Zhe;
Wu, Yinuo;
Luo, Haibin;
Zhang, Chen;
Huang, Ling;
Trabocchi, Andrea

Publication type:

Article

Novel Donepezil–Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease.

Published in:

Molecules, 2021, v. 26, n. 6, p. 1658, doi. 10.3390/molecules26061658

By:

Queda, Fausto;
Calò, Sonia;
Gwizdala, Karolina;
Magalhães, João D.;
Cardoso, Sandra M.;
Chaves, Sílvia;
Piemontese, Luca;
Santos, M. Amélia;
Plech, Tomasz;
Andres-Mach, Marta

Publication type:

Article

Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.

Published in:

Molecules, 2021, v. 26, n. 4, p. 1133, doi. 10.3390/molecules26041133

By:

Konkoľová, Eva;
Hudáčová, Monika;
Hamuľaková, Slávka;
Jendželovský, Rastislav;
Vargová, Jana;
Ševc, Juraj;
Fedoročko, Peter;
Kožurková, Mária;
Fantacuzzi, Marialuigia;
Ammazzalorso, Alessandra

Publication type:

Article

First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease.

Published in:

Molecules, 2021, v. 26, n. 1, p. 80, doi. 10.3390/molecules26010080

By:

Guieu, Benjamin;
Lecoutey, Cedric;
Legay, Rémi;
Davis, Audrey;
Sopkova de Oliveira Santos, Jana;
Altomare, Cosimo Damiano;
Catto, Marco;
Rochais, Christophe;
Dallemagne, Patrick;
Muñoz-Torrero, Diego;
De Pascual-Teresa, Beatriz

Publication type:

Article

New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment.

Published in:

Molecules, 2020, v. 25, n. 24, p. 5891, doi. 10.3390/molecules25245891

By:

Makhaeva, Galina F.;
Kovaleva, Nadezhda V.;
Rudakova, Elena V.;
Boltneva, Natalia P.;
Lushchekina, Sofya V.;
Faingold, Irina I.;
Poletaeva, Darya A.;
Soldatova, Yuliya V.;
Kotelnikova, Raisa A.;
Serkov, Igor V.;
Ustinov, Anatoly K.;
Proshin, Alexey N.;
Radchenko, Eugene V.;
Palyulin, Vladimir A.;
Richardson, Rudy J.;
Plech, Tomasz

Publication type:

Article

Sigma-2 Receptor—A Potential Target for Cancer/Alzheimer's Disease Treatment via Its Regulation of Cholesterol Homeostasis.

Published in:

Molecules, 2020, v. 25, n. 22, p. 5439, doi. 10.3390/molecules25225439

By:

Yang, Kai;
Zeng, Cheng;
Wang, Changcai;
Sun, Meng;
Yin, Dan;
Sun, Taolei

Publication type:

Article

Design and Synthesis of New Benzo[d]oxazole-Based Derivatives and Their Neuroprotective Effects on β-Amyloid-Induced PC12 Cells.

Published in:

Molecules, 2020, v. 25, n. 22, p. 5391, doi. 10.3390/molecules25225391

By:

Liu, Zheng;
Bian, Ming;
Ma, Qian-Qian;
Zhang, Zhuo;
Du, Huan-Huan;
Wei, Cheng-Xi

Publication type:

Article