Works matching DE "TACRINE"

Results: 250

Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel Coumarin–Triazole–Isatin Hybrids as Selective Butyrylcholinesterase Inhibitors.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2121, doi. 10.3390/molecules30102121

By:

Dimkovski, Aleksandar;
Dobričić, Vladimir;
Simić, Milena R.;
Jurhar Pavlova, Maja;
Mihajloska, Evgenija;
Sterjev, Zoran;
Poceva Panovska, Ana

Publication type:

Article

Multifunctional liposomes for nasal delivery of the anti-Alzheimer drug tacrine hydrochloride.

Published in:

Journal of Liposome Research, 2014, v. 24, n. 4, p. 323, doi. 10.3109/08982104.2014.899369

By:

Corace, Giuseppe;
Angeloni, Cristina;
Malaguti, Marco;
Hrelia, Silvana;
Stein, Paul C.;
Brandl, Martin;
Gotti, Roberto;
Luppi, Barbara

Publication type:

Article

Adjuvant Anticholinesterase Therapy for the Management of Epilepsy-Induced Memory Deficit: A Critical Pre-clinical Study.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 115, n. 6, p. 512, doi. 10.1111/bcpt.12275

By:

Mishra, Awanish;
Goel, Rajesh Kumar

Publication type:

Article

Potential Anti-Cholinesterase Activity of Bioactive Compounds Extracted from Cassia grandis L.f. and Cassia timoriensis DC.

Published in:

Plants (2223-7747), 2023, v. 12, n. 2, p. 344, doi. 10.3390/plants12020344

By:

Alhawarri, Maram B.;
Dianita, Roza;
Rawa, Mira Syahfriena Amir;
Nogawa, Toshihiko;
Wahab, Habibah A.

Publication type:

Article

Inhibitors of Acetylcholinesterase Derived from 7-Methoxytacrine and Their Effects on the Choline Transporter CHT1.

Published in:

Dementia & Geriatric Cognitive Disorders, 2017, v. 43, n. 1/2, p. 45, doi. 10.1159/000453256

By:

Kristofikova, Zdenka;
Ricny, Jan;
Soukup, Ondrej;
Korabecny, Jan;
Nepovimova, Eugenie;
Kuca, Kamil;
Ripova, Daniela

Publication type:

Article

Repurposing FDA‐Approved Compounds for the Discovery of Glutaminyl Cyclase Inhibitors as Drugs Against Alzheimer's Disease.

Published in:

ChemistryOpen, 2021, v. 10, n. 9, p. 877, doi. 10.1002/open.202000235

By:

Xu, Chenshu;
Zou, Haoman;
Yu, Xi;
Xie, Yazhou;
Cai, Jiaxin;
Shang, Qi;
Ouyang, Na;
Wang, Yinan;
Xu, Pan;
He, Zhendan;
Wu, Haiqiang

Publication type:

Article

Natural Corynanthe-Type Cholinesterase Inhibitors from Malaysian Uncaria attenuata Korth.: Isolation, Characterization, In Vitro and In Silico Studies.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 3, p. 390, doi. 10.3390/metabo13030390

By:

Chear, Nelson Jeng-Yeou;
Ching-Ga, Tan Ai Fein;
Khaw, Kooi-Yeong;
León, Francisco;
Tan, Wen-Nee;
Yusof, Siti R.;
McCurdy, Christopher R.;
Murugaiyah, Vikneswaran;
Ramanathan, Surash

Publication type:

Article

Design, synthesis, and pharmacological evaluation of heteroaryl thiol-linked kojic acid derivatives as a novel class of acetylcholinesterase inhibitors for Alzheimer's disease therapy.

Published in:

3 Biotech, 2025, v. 15, n. 5, p. 1, doi. 10.1007/s13205-025-04295-5

By:

Singh, Madan;
Karthikeyan, Chandrabose;
Waiker, Digambar Kumar;
Tiwari, Akhilesh;
Shrivastava, Sushant K.;
Sousa, Sérgio F.;
Kiriwan, Duangnapa;
Martins, Fábio G.;
Moorthy, Narayana Subbiah Hari Narayana

Publication type:

Article

DESIGN, SYNTHESIS, CHARACTERIZATION, BIOACTIVITY AND MOLECULAR DOCKING STUDIES OF NOVEL SULFAMIDES.

Published in:

Studia Universitatis Babes-Bolyai, Chemia, 2023, v. 68, n. 2, p. 145, doi. 10.24193/subbchem.2023.2.10

By:

NADERI, Ali;
AKINCIOĞLU, Akın;
ÇAĞAN, Ahmet;
GÖKSU, Süleyman;
TASLIMI, Parham;
GÜLÇIN, İlhami

Publication type:

Article

Buchwald--Hartwig Amination Approach for the Synthesis of Functionalized 1,2,3,4-Tetrahydroacridine Derivatives.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 16, p. 3468, doi. 10.1002/ejoc.201402122

By:

de Sousa, Julien;
Brown, Richard C. D.;
Baati, Rachid

Publication type:

Article

Ultrasound-assisted synthesis of benzothiazepines and assessment of their in vitro acetylcholinesterase inhibition activity.

Published in:

Green Chemistry Letters & Reviews, 2014, v. 7, n. 2, p. 158, doi. 10.1080/17518253.2014.909889

By:

Khan, Azhar U.;
Malik, Nazia;
Alam, Mahboob;
Lee, Dong-Ung

Publication type:

Article

Imino and Thioureidic Derivatives as New Tools for Alzheimer's Disease: Preliminary Studies.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 1, p. 1, doi. 10.1111/cbdd.70049

By:

Caruso, Anna;
Tommonaro, Giuseppina;
Vassallo, Antonio;
Paris, Debora;
Monné, Magnus;
Catalano, Alessia;
Sinicropi, Maria Stefania;
Saturnino, Carmela

Publication type:

Article

Bis(3)-Tacrine Inhibits the Sustained Potassium Current in Cultured Rat Hippocampal Neurons.

Published in:

Physiological Research, 2017, v. 66, n. 3, p. 539, doi. 10.33549/physiolres.933354

By:

WEN, R.-J.;
HUANG, D.;
ZHANG, Y.;
LIU, Y.-W.

Publication type:

Article

Modulation of erythrocyte acetylcholinesterase activity and its association with G protein-band 3 interactions.

Published in:

2009

By:

Carvalho, F. A.;
Lopes de Almeida, J. P.;
Freitas-Santos, T.;
Saldanha, C.;
de Almeida, J P Lopes

Publication type:

journal article

Synthesis and biological activities study of novel phthalimides and phenylpyrazolo[1,5- a ]pyrimidines.

Published in:

Journal of Chemical Research, 2021, v. 45, p. 731, doi. 10.1177/1747519821993433

By:

Tang, Long;
Jiang, Jianchun;
Song, Guoqiang;
Wang, Yajing;
Wei, Min;
Cao, Yijing;
Huang, Xianfeng;
Feng, Xiaoqing

Publication type:

Article

Synthesis, characterization, crystal structures, and the biological evaluation of 2-phenylthiazole derivatives as cholinesterase inhibitors.

Published in:

Journal of Chemical Research, 2021, v. 45, n. 5/6, p. 572, doi. 10.1177/1747519820976543

By:

Shi, Da-Hua;
Song, Meng-qiu;
Ma, Xiao-Dong;
Su, Jia-Bin;
Wang, Jing;
Wang, Xiu-Jun;
Liu, Yu-Wei;
Liu, Wei-Wei;
Si, Xin-Xin

Publication type:

Article

FARKLI NERGİS KÜLTÜR ÇEŞİTLERİ SOĞANLARININ IN VITRO ANTİOKSİDAN, ASETİLKOLİNESTERAZ VE BÜTİRİLKOLİNESTERAZ AKTİVİTELERİ.

Published in:

Eskişehir Technical University Journal of Science & Technology C - Life Sciences & Biotechnology, 2021, v. 9, n. 2, p. 90, doi. 10.18036/estubtdc.574441

By:

ERÖZ POYRAZ, İlham;
KIYAN, H. Tuba;
ZEYBEKOĞLU, Emrah;
ÖZZAMBAK, M. Ercan;
ÖZTÜRK, Nilgün

Publication type:

Article

Study on the Effect of Phaseolus vulgaris Methanol Extract on Haloperidol and Tacrine Induced Parkinsonism.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2022, v. 56, n. 3, p. 804, doi. 10.5530/ijper.56.3.131

By:

Kaur, Balvinder;
Saxena, Jyoti

Publication type:

Article

SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2019, v. 53, n. 2, p. 268, doi. 10.5530/ijper.53.2.35

By:

Ökten, Salih;
Ekiz, Makbule;
Tutar, Ahmet;
Bütün, Burcu;
Koçyiğit, Ümit Muhammet;
Topçu, Gülaçtı;
Gülçin, İlhami

Publication type:

Article

A Bioorthogonally Synthesized and Disulfide-Containing Fluorescence Turn-On Chemical Probe for Measurements of Butyrylcholinesterase Activity and Inhibition in the Presence of Physiological Glutathione.

Published in:

Catalysts (2073-4344), 2020, v. 10, n. 10, p. 1169, doi. 10.3390/catal10101169

By:

Gong, Ming-Mao;
Dai, Chia-Yen;
Severance, Scott;
Hwang, Chi-Ching;
Fang, Bo-Kai;
Lin, Heng-Bo;
Huang, Chien-Hui;
Ong, Chi-Wi;
Wang, Jeh-Jeng;
Lee, Pei-Lun;
Wang, Tzu-Pin

Publication type:

Article

Design, synthesis and the evaluation of cholinesterase inhibition and blood‐brain permeability of daidzein derivatives or analogs.

Published in:

Chemical Biology & Drug Design, 2023, v. 102, n. 4, p. 718, doi. 10.1111/cbdd.14279

By:

Wang, Yi‐Hui;
Gao, Xiao‐Hui;
Li, Xuan;
Ding, Yu‐Jie;
Shi, Qing;
Yang, Zhi‐Yu;
Peng, Dian;
Liu, Hao‐Ran

Publication type:

Article

Synthesis and inhibitory activities of inhibitors for the treatment of Alzheimer's disease.

Published in:

Chemical Biology & Drug Design, 2022, v. 99, n. 5, p. 727, doi. 10.1111/cbdd.14016

By:

Zhou, Shiyang;
Huang, Gangliang

Publication type:

Article

Histamine H<sub>3</sub> receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.

Published in:

2021

By:

Lopes, Flávia B.;
Aranha, Cecília M. S. Q.;
Fernandes, João Paulo S.

Publication type:

Literature Review

Novel tetrahydroacridine derivatives with iodobenzoic acid moiety as multifunctional acetylcholinesterase inhibitors.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 505, doi. 10.1111/cbdd.13111

By:

Skibiński, Robert;
Czarnecka, Kamila;
Girek, Małgorzata;
Bilichowski, Ireneusz;
Chufarova, Nina;
Mikiciuk‐Olasik, Elżbieta;
Szymański, Paweł

Publication type:

Article

New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease.

Published in:

Chemical Biology & Drug Design, 2016, v. 87, n. 1, p. 101, doi. 10.1111/cbdd.12633

By:

Keri, Rangappa S.;
Quintanova, Catarina;
Chaves, Sílvia;
Silva, Diana F.;
Cardoso, Sandra M.;
Santos, M. Amélia

Publication type:

Article

Novel conjugates of tacrine with 1,2,4,-thiadiazole as highly effective cholinesterase inhibitors, blockers of NMDA receptors, and antioxidants.

Published in:

Doklady Biochemistry & Biophysics, 2017, v. 477, n. 1, p. 405, doi. 10.1134/S1607672917060163

By:

Makhaeva, G.;
Grigoriev, V.;
Proshin, A.;
Kovaleva, N.;
Rudakova, E.;
Boltneva, N.;
Serkov, I.;
Bachurin, S.

Publication type:

Article

Bioactivation and detoxification of organophosphorus pesticides in freshwater planarians shares similarities with humans.

Published in:

Archives of Toxicology, 2022, v. 96, n. 12, p. 3233, doi. 10.1007/s00204-022-03387-y

By:

Ireland, Danielle;
Rabeler, Christina;
Gong, TaiXi;
Collins, Eva-Maria S.

Publication type:

Article

Insight into Isolation and Characterization of Phenolic Compounds from Hawthorn (Crataegus pinnatifida Bge.) with Antioxidant, Anti-Acetylcholinesterase, and Neuroprotective Activities.

Published in:

Plant Foods for Human Nutrition, 2022, v. 77, n. 4, p. 538, doi. 10.1007/s11130-022-01004-y

By:

Liu, De-Feng;
Bai, Ming;
Du, Ning-Ning;
Shen, Shuai;
Li, Zhi-Yuan;
Zhang, Xin;
Guo, Rui;
Yao, Guo-Dong;
Song, Shao-Jiang;
Huang, Xiao-Xiao

Publication type:

Article

Phenolic Profiles, Antioxidant, and Inhibitory Activities of Kadsura heteroclita (Roxb.) Craib and Kadsura coccinea (Lem.) A.C. Sm.

Published in:

Foods, 2020, v. 9, n. 9, p. 1222, doi. 10.3390/foods9091222

By:

Sritalahareuthai, Varittha;
Temviriyanukul, Piya;
On-nom, Nattira;
Charoenkiatkul, Somsri;
Suttisansanee, Uthaiwan

Publication type:

Article

NOVEL TACRINE AND HESPERETIN ANALOGUES: DESIGN, MOLECULAR DOCKING AND IN SILICO ADME STUDIES TO IDENTIFY POTENTIAL ACETYL CHOLINE ESTERASE INHIBITORS FOR ALZHEIMER'S DISEASE.

Published in:

Journal of Faculty of Pharmacy of Ankara University / Ankara Üniversitesi Eczacilik Fakültesi Dergisi, 2020, v. 44, n. 1, p. 18, doi. 10.33483/jfpau.559509

By:

NARESH, Kondapalli;
SRUTHI, Kanna

Publication type:

Article

Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42239-2

By:

Soliman, Aiten M.;
Ghorab, Walid M.;
Lotfy, Dina M.;
Karam, Heba M.;
Ghorab, Mostafa M.;
Ramadan, Laila A.

Publication type:

Article

Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42239-2

By:

Soliman, Aiten M.;
Ghorab, Walid M.;
Lotfy, Dina M.;
Karam, Heba M.;
Ghorab, Mostafa M.;
Ramadan, Laila A.

Publication type:

Article

The anti-Alzheimer potential of novel spiroindolin-1,2-diazepine derivatives as targeted cholinesterase inhibitors with modified substituents.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38236-0

By:

Pourtaher, Hormoz;
Hasaninejad, Alireza;
Zare, Shahrokh;
Tanideh, Nader;
Iraji, Aida

Publication type:

Article

Polymer drug conjugates containing memantine, tacrine and cinnamic acid: promising nanotherapeutics for the treatment of Alzheimer's disease.

Published in:

Journal of Microencapsulation, 2023, v. 40, n. 1, p. 15, doi. 10.1080/02652048.2023.2167011

By:

Naki, Tobeka;
Matshe, William Morwa Reagile;
Balogun, Mohammed Olusegun;
Sinha Ray, Suprakas;
Egieyeh, Samuel Ayodele;
Aderibigbe, Blessing Atim

Publication type:

Article

STUDY OF ELECTROCHEMICAL BEHAVIOR OF TWO CHEMICALLY SIMILAR ACRIDINES: TACRINE AND 9-AMINOACRIDINE ON HANGING MERCURY DROP ELECTRODE.

Published in:

Bulletin of the Chemical Society of Ethiopia, 2021, v. 35, n. 3, p. 69, doi. 10.4314/bcse.v35i3.14

By:

Badulla, Wafa F. S.;
Hussein, Weiam A. A.;
Arli, Goksal

Publication type:

Article

Identification of Miscanthus floridulus as a promising anti-Alzheimer's disease and antidiabetic agent through bioactivity evaluations and chemical composition analyses.

Published in:

Arabian Journal of Chemistry, 2024, v. 17, n. 12, p. N.PAG, doi. 10.1016/j.arabjc.2024.106037

By:

Zhao, Dingping;
Dai, Qijun;
Zhang, Yuanyuan;
Shen, Hongjian;
Mao, Yan;
Zhou, Xianxian;
Chen, Xiqing;
pang, Hanqing;
Wang, Hui;
Liu, Liang

Publication type:

Article

SAR studies of quinoline and derivatives as potential treatments for Alzheimer's disease.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 2, p. N.PAG, doi. 10.1016/j.arabjc.2022.104502

By:

Li, Zhao-Hui;
Yin, Li-Quan;
Zhao, Dong-Hai;
Jin, Lian-Hai;
Sun, Ya-Juan;
Tan, Cheng

Publication type:

Article

Exploring facile synthesis and cholinesterase inhibiting potential of heteroaryl substituted imidazole derivatives for the treatment of Alzheimer's disease.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 1, p. N.PAG, doi. 10.1016/j.arabjc.2022.104384

By:

Chaudhry, Faryal;
Munir, Rubina;
Ashraf, Muhammad;
Mehr-un-Nisa;
Huma, Rahila;
Malik, Nayab;
Hussain, Safdar;
Ali Munawar, Munawar;
Ain Khan, Misbahul

Publication type:

Article

The design of fluoroquinolone-based cholinesterase inhibitors: Synthesis, biological evaluation and in silico docking studies.

Published in:

Arabian Journal of Chemistry, 2021, v. 14, n. 7, p. N.PAG, doi. 10.1016/j.arabjc.2021.103211

By:

Mansha, Muhammad;
Taha, Muhammad;
Hassane Anouar, El;
Ullah, Nisar

Publication type:

Article

NOVEL 1,2,4-OXADIAZOLE DERIVATIVES AS SELECTIVE BUTYRYLCHOLINESTERASE INHIBITORS: DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION.

Published in:

EXCLI Journal, 2021, v. 20, p. 907, doi. 10.17179/excli2021-3569

By:

Nazari, Maryam;
Rezaee, Elham;
Hariri, Roshanak;
Akbarzadeh, Tahmineh;
Tabatabai, Sayyed Abbas

Publication type:

Article

In silico study of tacrine and acetylcholine binding profile with human acetylcholinesterase: docking and electronic structure.

Published in:

Journal of Molecular Modeling, 2022, v. 28, n. 9, p. 1, doi. 10.1007/s00894-022-05252-2

By:

Nascimento, Letícia A.;
Nascimento, Érica C. M.;
Martins, João B. L.

Publication type:

Article

Structure–activity relationship of tacrine and its analogues in relation to inhibitory activity against Alzheimer's disease.

Published in:

Journal of Molecular Modeling, 2019, v. 25, n. 5, p. N.PAG, doi. 10.1007/s00894-019-3993-8

By:

Vieira, Ingrid;
Camargo, Lilian T. F. M.;
Ribeiro, Luciano;
Rodrigues, Allane C. C.;
Camargo, Ademir J.

Publication type:

Article

Antioxidant, antiepileptic, and anticholinergic properties of 4′,5,7-Trihydroxy-3,6-dimethoxyflavone as natural phenolic compound: a toxicology approach.

Published in:

Toxin Reviews, 2021, v. 40, n. 3, p. 292, doi. 10.1080/15569543.2019.1610894

By:

Durmaz, Lokman

Publication type:

Article

Purification of Acetylcholinesterase by 9-Amino-1,2,3,4-tetrahydroacridine from Human Erythrocytes.

Published in:

Applied Biochemistry & Biotechnology, 2013, v. 170, n. 1, p. 198, doi. 10.1007/s12010-013-0177-3

By:

Kaya, Habibe;
Özcan, Bilge;
Şişecioğlu, Melda;
Ozdemir, Hasan

Publication type:

Article

Platinum (II) Schiff Base Complexes and their Effects on the Inhibition of Amyloid β<sub>1–42</sub> Aggregation.

Published in:

Applied Organometallic Chemistry, 2024, v. 38, n. 8, p. 1, doi. 10.1002/aoc.7540

By:

İrişli, Sevil;
Günnaz, Salih;
Özcan, Özge;
Arı, Aydan;
Maral, Meltem;
Erdem, Arzum;
Özel, Derya;
Yurt, Fatma

Publication type:

Article

Effects of Anti-Alzheimer Drugs on Phosphorylation and Assembly of Microtubules from Brain Microtubular Proteins.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 156, n. 6, p. 768, doi. 10.1007/s10517-014-2445-9

By:

Shevtsov, P.;
Shevtsova, E.;
Burbaeva, G.;
Bachurin, S.

Publication type:

Article

Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats.

Published in:

Drug & Chemical Toxicology, 2021, v. 44, n. 2, p. 207, doi. 10.1080/01480545.2019.1566350

By:

Zdarova Karasova, Jana;
Soukup, Ondrej;
Korabecny, Jan;
Hroch, Milos;
Krejciova, Marketa;
Hrabinova, Martina;
Misik, Jan;
Novotny, Ladislav;
Hepnarova, Vendula;
Kuca, Kamil

Publication type:

Article

Development of new treatment for Alzheimer's disease: targeting cholesterol.

Published in:

2024

By:

Xinhua SHU

Publication type:

Abstract

Design, Synthesis, Biological Activity, and Molecular Modeling of Novel Spiroquinazoline Derivatives as Acetylcholinesterase Inhibitors for Alzheimer Disease.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 9, p. 8082, doi. 10.1080/10406638.2022.2144911

By:

Shtaiwi, Majed;
Aljaar, Nayyef;
Al-Najjar, Lana;
Malakar, Chandi C.;
Shtaiwi, Amneh;
Abu-Sini, Mohammad;
Al-Refai, Mahmoud

Publication type:

Article

Synthesis, biological evaluation, and computational studies of N-benzyl pyridinium–curcumin derivatives as potent AChE inhibitors with antioxidant activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2281264

By:

Al-Rifai, Nafisah M.;
Al-Khalileh, Nemeh M.;
Zahra, Jalal A.;
El-Barghouthi, Musa I.;
Darras, Fouad H.

Publication type:

Article