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Synthesis of novel aryl-substituted 2-aminopyridine derivatives by the cascade reaction of 1,1-enediamines with vinamidinium salts to develop novel anti-Alzheimer agents.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-64179-1
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- Article
Tailored Melatonin- and Donepezil-Based Hybrids Targeting Pathognomonic Changes in Alzheimer's Disease: An In Vitro and In Vivo Investigation.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5969, doi. 10.3390/ijms25115969
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- Article
A New Prenylated Hydroquinone from the Fruiting Bodies of Ganoderma calidophilum.
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- Chemistry of Natural Compounds, 2024, v. 60, n. 3, p. 403, doi. 10.1007/s10600-024-04337-z
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- Article
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease.
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- Molecules, 2024, v. 29, n. 8, p. 1782, doi. 10.3390/molecules29081782
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- Article
Design, Synthesis and Molecular Modeling Study of Radiotracers Based on Tacrine and Its Derivatives for Study on Alzheimer's Disease and Its Early Diagnosis.
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- Applied Sciences (2076-3417), 2024, v. 14, n. 7, p. 2827, doi. 10.3390/app14072827
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- Article
Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities.
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- Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 4, p. 1, doi. 10.1002/jbt.23706
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- Article
A Sustainable Synthetic Approach to Tacrine and Cholinesterase Inhibitors in Deep Eutectic Solvents under Aerobic Conditions.
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- Molecules, 2024, v. 29, n. 6, p. 1399, doi. 10.3390/molecules29061399
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- Article
New Multitarget Rivastigmine–Indole Hybrids as Potential Drug Candidates for Alzheimer's Disease.
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- Pharmaceutics, 2024, v. 16, n. 2, p. 281, doi. 10.3390/pharmaceutics16020281
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- Article
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
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- Molecules, 2024, v. 29, n. 2, p. 321, doi. 10.3390/molecules29020321
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- Article
Potential of Tryptamine Derivatives as Multi-Target Directed Ligands for Alzheimer's Disease: AChE, MAO-B, and COX-2 as Molecular Targets.
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- Molecules, 2024, v. 29, n. 2, p. 490, doi. 10.3390/molecules29020490
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- Article
Development of new treatment for Alzheimer's disease: targeting cholesterol.
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- 2024
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- Abstract
Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42239-2
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- Article
Research on Secondary Metabolites From the Soft Coral-Associated Fungus Aspergillus sydowii SCSIO41203 and Their Bioactivities.
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- Natural Product Communications, 2023, v. 18, n. 11, p. 1, doi. 10.1177/1934578X231213220
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- Article
Design, synthesis and the evaluation of cholinesterase inhibition and blood‐brain permeability of daidzein derivatives or analogs.
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- Chemical Biology & Drug Design, 2023, v. 102, n. 4, p. 718, doi. 10.1111/cbdd.14279
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- Article
New Benzamides as Multi-Targeted Compounds: A Study on Synthesis, AChE and BACE1 Inhibitory Activity and Molecular Docking.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14901, doi. 10.3390/ijms241914901
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- Article
Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42239-2
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- Publication type:
- Article
Unfolding the Antibacterial Activity and Acetylcholinesterase Inhibition Potential of Benzofuran-Triazole Hybrids: Synthesis, Antibacterial, Acetylcholinesterase Inhibition, and Molecular Docking Studies.
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- Molecules, 2023, v. 28, n. 16, p. 6007, doi. 10.3390/molecules28166007
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- Article
The anti-Alzheimer potential of novel spiroindolin-1,2-diazepine derivatives as targeted cholinesterase inhibitors with modified substituents.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38236-0
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- Publication type:
- Article
Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9124, doi. 10.3390/ijms24119124
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- Article
Chemical and Biological Evaluation of Novel 1 H -Chromeno[3,2- c ]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 7724, doi. 10.3390/ijms24097724
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- Article
Novel indolotacrine hybrids as acetylcholinesterase inhibitors: design, synthesis, biological evaluation, and molecular docking studies.
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- Journal of the Iranian Chemical Society, 2023, v. 20, n. 5, p. 1049, doi. 10.1007/s13738-022-02726-1
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- Article
Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives.
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- Molecules, 2023, v. 28, n. 8, p. 3357, doi. 10.3390/molecules28083357
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- Article
Phytochemical Characterization and In Vitro and In Silico Biological Studies from Ferns of Genus Blechnum (Blechnaceae, Polypodiales).
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- Antioxidants, 2023, v. 12, n. 3, p. 540, doi. 10.3390/antiox12030540
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- Article
Natural Corynanthe-Type Cholinesterase Inhibitors from Malaysian Uncaria attenuata Korth.: Isolation, Characterization, In Vitro and In Silico Studies.
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- Metabolites (2218-1989), 2023, v. 13, n. 3, p. 390, doi. 10.3390/metabo13030390
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- Article
Protective Effects of Quercetin in Combination with Donepezil against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress in Glioblastoma Cells.
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- Pharmaceutical Chemistry Journal, 2023, v. 56, n. 12, p. 1577, doi. 10.1007/s11094-023-02830-3
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- Publication type:
- Article
Design, Synthesis, and Neuroprotective Activity of Phenoxyindole Derivatives on Antiamyloid Beta (Aβ) Aggregation, Antiacetylcholinesterase, and Antioxidant Activities.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 3, p. 355, doi. 10.3390/ph16030355
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- Article
Neuroprotective Activities of New Monoterpenoid Indole Alkaloid from Nauclea officinalis.
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- Processes, 2023, v. 11, n. 3, p. 646, doi. 10.3390/pr11030646
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- Article
Multitargeted C9‐substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics.
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- Drug Development Research, 2023, v. 84, n. 1, p. 121, doi. 10.1002/ddr.22017
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- Article
Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2285, doi. 10.3390/ijms24032285
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- Article
Anti-Neuroinflammatory Potential of Natural Products in the Treatment of Alzheimer's Disease.
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- Molecules, 2023, v. 28, n. 3, p. 1486, doi. 10.3390/molecules28031486
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- Article
Biologically Potent Benzimidazole-Based-Substituted Benzaldehyde Derivatives as Potent Inhibitors for Alzheimer's Disease along with Molecular Docking Study.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 2, p. 208, doi. 10.3390/ph16020208
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- Article
Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer's Inhibitors.
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- Molecules, 2023, v. 28, n. 2, p. 559, doi. 10.3390/molecules28020559
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- Article
Potential Anti-Cholinesterase Activity of Bioactive Compounds Extracted from Cassia grandis L.f. and Cassia timoriensis DC.
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- Plants (2223-7747), 2023, v. 12, n. 2, p. 344, doi. 10.3390/plants12020344
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- Article
Application of Marine Natural Products against Alzheimer's Disease: Past, Present and Future.
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- Marine Drugs, 2023, v. 21, n. 1, p. 43, doi. 10.3390/md21010043
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- Article
Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.
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- Molecules, 2023, v. 28, n. 1, p. 238, doi. 10.3390/molecules28010238
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- Article
Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer's disease.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1058358
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- Article
Bioactivation and detoxification of organophosphorus pesticides in freshwater planarians shares similarities with humans.
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- Archives of Toxicology, 2022, v. 96, n. 12, p. 3233, doi. 10.1007/s00204-022-03387-y
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- Publication type:
- Article
Insight into Isolation and Characterization of Phenolic Compounds from Hawthorn (Crataegus pinnatifida Bge.) with Antioxidant, Anti-Acetylcholinesterase, and Neuroprotective Activities.
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- Plant Foods for Human Nutrition, 2022, v. 77, n. 4, p. 538, doi. 10.1007/s11130-022-01004-y
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- Publication type:
- Article
Synthesis of 3,5-Disubstituted-1,2,4-oxadiazole Sulfonamides in the Superbasic t-BuONa/DMAA System.
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- Russian Journal of General Chemistry, 2022, v. 92, n. 12, p. 2982, doi. 10.1134/S1070363222120568
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- Article
From tryptamine to the discovery of efficient multi-target directed ligands against cholinesterase-associated neurodegenerative disorders.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1036030
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- Article
Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13925, doi. 10.3390/ijms232213925
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- Article
Anticholinesterase activity of Areca Catechu: In Vitro and in silico green synthesis approach in search for therapeutic agents against Alzheimer’s disease.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1044248
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- Publication type:
- Article
New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones.
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- Biomolecules (2218-273X), 2022, v. 12, n. 11, p. 1551, doi. 10.3390/biom12111551
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- Article
In Silico and In Vitro Studies of Benzothiazole-Isothioureas Derivatives as a Multitarget Compound for Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 12945, doi. 10.3390/ijms232112945
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- Publication type:
- Article
SYNTHESIS AND CHARACTERIZATION OF SCHIFF BASES CONTAINING 1,2,3-TRIAZOLE UNIT: PHOTOPHYSICAL AND ACETYL CHOLINE (AChE) INHIBITORY PROPERTIES.
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- Journal of Structural Chemistry, 2022, v. 63, n. 11, p. 1787, doi. 10.1134/S0022476622110087
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- Article
New bis(pyrazolo[3,4-b]pyridines) and bis(thieno[2,3-b]pyridines) as potential acetylcholinesterase inhibitors: synthesis, in vitro and SwissADME prediction study.
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- Journal of the Iranian Chemical Society, 2022, v. 19, n. 11, p. 4457, doi. 10.1007/s13738-022-02614-8
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- Publication type:
- Article
Synthesis, biological evaluation, and molecular docking study of novel 1,2,4-substituted triazoles as inhibitors of alzheimer's disease.
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- Journal of the Iranian Chemical Society, 2022, v. 19, n. 11, p. 4491, doi. 10.1007/s13738-022-02617-5
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- Publication type:
- Article
Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Studies of Indole Based Thiadiazole Derivatives as Dual Inhibitor of Acetylcholinesterase and Butyrylchloinesterase.
- Published in:
- Molecules, 2022, v. 27, n. 21, p. 7368, doi. 10.3390/molecules27217368
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- Article
Synthesis of Novel Bromophenol with Diaryl Methanes—Determination of Their Inhibition Effects on Carbonic Anhydrase and Acetylcholinesterase.
- Published in:
- Molecules, 2022, v. 27, n. 21, p. 7426, doi. 10.3390/molecules27217426
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- Article
Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction.
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- Pharmaceutics, 2022, v. 14, n. 11, p. 2342, doi. 10.3390/pharmaceutics14112342
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- Publication type:
- Article