Works matching DE "T-cell exhaustion"

Results: 777

S-adenosylmethionine metabolism shapes CD8+ T cell functions in colorectal cancer.

Published in:

Cancer & Metabolism, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40170-025-00394-2

By:

Yang, Xiaohua;
Kou, Tianzhang;
Wang, Hongmiao;
Zhu, Ji;
Zhu, Zheng-Jiang;
Cai, Yuping

Publication type:

Article

Editorial: Enhancing T cell function: innovations in cancer immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1615030

By:

Zhang, Ji;
Zhao, Qihao;
Sun, Qian;
Jiang, Hong;
Oksenych, Valentyn;
Wang, Xuefeng

Publication type:

Article

Role of USP10/METTL3/CXCR4 Axis in Immunotherapy of Castration-Resistant Prostate Cancer.

Published in:

Iranian Journal of Allergy, Asthma & Immunology, 2025, v. 24, n. 3, p. 334, doi. 10.18502/ijaai.v24i3.18683

By:

Wu Chen;
Lijun Xu;
Haibo Deng;
Zhenyan Zhu;
Dongrong Yang

Publication type:

Article

Expression and Clinical Significance of CXCR5 and LAG‐3 on Peripheral Blood CD8+ T Cells in Patients With Diffuse Large B‐Cell Lymphoma.

Published in:

Kaohsiung Journal of Medical Sciences, 2025, v. 41, n. 5, p. 1, doi. 10.1002/kjm2.70005

By:

Guo, Xi‐Zhe;
Guo, Ya‐Fei;
Wu, Shi‐Xin

Publication type:

Article

The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1577803

By:

Long, Qiuyue;
Song, Shixu;
Xue, Jianbo;
Yu, Wenyi;
Zheng, Yaolin;
Li, Jiwei;
Wu, Jing;
Hu, Xiaoyi;
Jiang, Mingzheng;
Ye, Hongli;
Zheng, Binghan;
Wang, Minghui;
Wu, Fangfang;
Li, Ke;
Gao, Zhancheng;
Zheng, Yali

Publication type:

Article

Unraveling the Heterogeneity of CD8+ T-Cell Subsets in Liver Cirrhosis: Implications for Disease Progression.

Published in:

Gut & Liver, 2025, v. 19, n. 3, p. 410, doi. 10.5009/gnl230345

By:

Kepu Zheng;
Leiyang Dai;
Shengning Zhang;
Yingpeng Zhao;
Wang Li;
Yang Gao;
Yuanyi Mang;
Lingfeng Jiao;
Yu Tang;
Jianghua Ran

Publication type:

Article

Editorial: Interaction of cell subtypes in tumor microenvironment, and implications for immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1600338

By:

Jiang, Hong;
Fu, Lingfeng;
Ishimoto, Takatsugu;
Zhang, Tao;
Zhang, Jun

Publication type:

Article

Safety and necessity of omitting mediastinal lymph node dissection in cN0/N1 non-small cell lung cancer after neoadjuvant immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587658

By:

Zhou, Yuheng;
Zhai, Wenyu;
Sun, Weizhen;
Han, Yongping;
Lin, Zhichao;
Liu, Dihan;
Zheng, Yan;
Luo, Xiaojuan;
Zhao, Zerui;
Feng, Shoucheng;
Lin, Yaobin;
Tang, Hailin;
Long, Hao

Publication type:

Article

Egg-driven immunosuppression and granuloma zonation in Peyer's patches of mice with Schistosoma japonicum infection.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1587166

By:

Li, Linzhu;
Wu, Jing;
Cao, Guangxu;
Yao, Jiakai;
Miao, Yanping;
Zhuang, Yanglin;
Xiang, Yushen;
Zhong, Xiaolin;
Liu, Yicong;
Chen, Fubo;
Dai, Yalei;
Dai, Yang;
Xu, Xindong;
Zhang, Qingfeng

Publication type:

Article

Deciphering the Premetastatic Lymphatic Niche of Oral Squamous Cell Carcinoma.

Published in:

Journal of Dental Research, 2025, v. 104, n. 6, p. 679, doi. 10.1177/00220345241307894

By:

Cao, C.;
Huang, Y.C.;
Luo, H.C.;
He, J.L.;
Wang, R.C.;
Yang, F.;
Meng, W.R.;
Li, L.;
Zhu, G.Q.

Publication type:

Article

IL-11/IL-11R signal inhibition by 9MW3811 remodels immune tumor microenvironment and enhances anti-tumor efficacy of PD-1 blockade.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00913-w

By:

Zhang, Chang;
Jiao, Shasha;
Zeng, Dadi;
Jiang, Wen;
Wang, Rongjuan;
Zheng, Bin;
Wang, Min;
Wang, Shuang;
Gui, Xun

Publication type:

Article

Single-cell multiomic analysis unveils the immune landscape dynamics of graves' ophthalmopathy.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08115-7

By:

Ke, Shurui;
Liu, Zhong;
Zhou, Ming;
Xiao, Bing;
Hu, Qiuling;
Lin, Jinshan;
Ye, Huijing;
Luo, Lixia;
Lin, Xianchai

Publication type:

Article

Construction of a novel CD8T cell-related index for predicting clinical outcomes and immune landscape in ovarian cancer by combined single-cell and RNA-sequencing analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02582-4

By:

Zhang, Yu;
Wan, Peng;
Wang, Liangliang;
Ren, Ruiping

Publication type:

Article

SPP1 + macrophages cause exhaustion of tumor-specific T cells in liver metastases.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59529-0

By:

Trehan, Rajiv;
Huang, Patrick;
Zhu, Xiao Bin;
Wang, Xin;
Soliman, Marlaine;
Strepay, Dillon;
Nur, Amran;
Kedei, Noemi;
Arhin, Martin;
Ghabra, Shadin;
Rodríguez-Matos, Francisco;
Benmebarek, Mohamed-Reda;
Ma, Chi;
Korangy, Firouzeh;
Greten, Tim F.

Publication type:

Article

Mitochondrial function changes in T cell subsets during radiotherapy for patients with nasopharyngeal carcinoma.

Published in:

Oncology Letters, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/ol.2025.15019

By:

Wang, Quan;
Yin, Xiangzhi;
Liu, Hongbo;
Wang, Qing;
Zhang, Lu;
Wang, Yifan;
Lu, Haijun

Publication type:

Article

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1586867

By:

Zhu, Fengzhi;
Yan, Helen Hoi Ning;
Tong, Yin;
Zhao, Yueliang

Publication type:

Article

Editorial: Community series in novel biomarkers in tumor immunity and immunotherapy, volume II.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1608903

By:

Elkord, Eyad;
Matsutani, Takaji

Publication type:

Article

Thrombospondin-1 induces CD8+ T cell exhaustion and immune suppression within the tumor microenvironment of ovarian cancer.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01668-5

By:

Liang, Haiyan;
Zhang, Suwei

Publication type:

Article

Editorial: Recent advances in thermal and nonthermal ablative technologies of the thyroid.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1601452

By:

Pace-Asciak, Pia;
Tufano, Ralph P.

Publication type:

Article

European survey on CAR T-Cell analytical methods from apheresis to post-infusion immunomonitoring.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1567582

By:

De Angelis, Biagio;
D'Amore, Maria Luisa;
Lecot, Pacôme;
Neininger, Kerstin;
Lorrain, Margot;
Gambotti, Laetitia;
Dreuillet, Caroline;
Courcault, Elise;
Chatterjee, Sampurna;
Delgado, Julio;
Galy, Anne;
Franz, Paul;
Rodriguez-Madoz, Juan Roberto;
Cabrerizo, Yolanda;
Richter, Anne;
Girvalaki, Charis;
Noviello, Maddalena;
Tassi, Elena;
Sanges, Carmen;
Luu, Maik

Publication type:

Article

抑制 CAR-T 细胞衰竭的策略研究.

Published in:

Journal of New Medicine, 2025, v. 56, n. 4, p. 337, doi. 10.12464/j.issn.0253-9802.2024-0331

By:

符琼玉;
郝新宝;
陶石

Publication type:

Article

Advances in strategies to improve the immunotherapeutic efficacy of chimeric antigen receptor-T cell therapy for lymphoma.

Published in:

Cancer Biology & Medicine, 2025, v. 22, n. 4, p. 301, doi. 10.20892/j.issn.2095-3941.2024.0538

By:

Tianshu Yu;
Xianhuo Wang;
Ou Bai;
Huilai Zhang;
Wenbin Qian

Publication type:

Article

From ex vivo to in vitro models: towards a novel approach to investigate the efficacy of immunotherapies on exhausted Vγ9Vδ2 T cells?

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1556982

By:

Chauvet, Morgane;
Bourges, Dorothée;
Scotet, Emmanuel

Publication type:

Article

MYC networks associate with decreased CD8 T-cell presence in diffuse large B-cell lymphoma and may be addressed by the synergistic combination of AZD4573 and Selinexor – a preliminary analysis.

Published in:

Annals of Hematology, 2025, v. 104, n. 4, p. 2403, doi. 10.1007/s00277-025-06298-x

By:

Rutz, Alison C.;
Weber, Kennedee S.;
Forberg, Aidan L.;
Nik, Adam;
Unrau, Jordan;
Hemmen, Ainslee J.;
Minicozzi, Michael;
Hartert, Keenan T.

Publication type:

Article

Increased PAFAH1B3 was associated with poor prognosis and T-cell exhaustion microenvironment in hepatocellular carcinoma.

Published in:

Discover Oncology, 2023, v. 14, n. 1, p. 1, doi. 10.1007/s12672-023-00845-6

By:

Zhang, Genhao

Publication type:

Article

Prognostic clinical phenotypes associated with tumor stemness in the immune microenvironment of T-cell exhaustion for hepatocellular carcinoma.

Published in:

Discover Oncology, 2023, v. 14, n. 1, p. 1, doi. 10.1007/s12672-023-00819-8

By:

Zhang, Genhao

Publication type:

Article

A breast cancer classification and immune landscape analysis based on cancer stem-cell-related risk panel.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00482-w

By:

Hu, Haihong;
Zou, Mingxiang;
Hu, Hongjuan;
Hu, Zecheng;
Jiang, Lingxiang;
Escobar, David;
Zhu, Hongxia;
Zhan, Wendi;
Yan, Ting;
Zhang, Taolan

Publication type:

Article

Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00403-x

By:

Barrera, Cristian;
Corredor, Germán;
Viswanathan, Vidya Sankar;
Ding, Ruiwen;
Toro, Paula;
Fu, Pingfu;
Buzzy, Christina;
Lu, Cheng;
Velu, Priya;
Zens, Philipp;
Berezowska, Sabina;
Belete, Merzu;
Balli, David;
Chang, Han;
Baxi, Vipul;
Syrigos, Konstantinos;
Rimm, David L.;
Velcheti, Vamsidhar;
Schalper, Kurt;
Romero, Eduardo

Publication type:

Article

Targeting SCD triggers lipotoxicity of cancer cells and enhances anti-tumor immunity in breast cancer brain metastasis mouse models.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07977-1

By:

Sammarco, Alessandro;
Guerra, Giorgia;
Eyme, Katharina M.;
Kennewick, Kelly;
Qiao, Yu;
El Hokayem, Joelle;
Williams, Kevin J.;
Su, Baolong;
Cakici, Cagri;
Mnatsakanyan, Hayk;
Zappulli, Valentina;
Bensinger, Steven J.;
Badr, Christian E.

Publication type:

Article

Heat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02046-8

By:

Yan, Lei;
Chen, Yumei;
Yang, Yilin;
Han, Yi;
Tong, Chaoyang

Publication type:

Article

ESMO news – May 2024.

Published in:

Oncolog-Hematolog, 2024, n. 67, p. 5

By:

C., Alexandru

Publication type:

Article

Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91705

By:

Karlsson, Joakim W.;
Sah, Vasu R.;
Bagge, Roger Olofsson;
Kuznetsova, Irina;
Iqba, Munir;
Alsen, Samuel;
Stenqvist, Sofia;
Saxena, Alka;
Ny, Lars;
Nilsson, Lisa M.;
Nilsson, Jonas A.

Publication type:

Article

Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.94899

By:

Semenova, Lesia;
Yingfan Wang;
Falcinelli, Shane;
Archin, Nancie;
Cooper-Volkheimer, Alicia D.;
Margolis, David M.;
Goonetilleke, Nilu;
Murdoch, David M.;
Rudin, Cynthia D.;
Browne, Edward P.

Publication type:

Article

Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83737

By:

Blanch-Lombarte, Oscar;
Ouchi, Dan;
Jimenez-Moyano, Esther;
Carabelli, Julieta;
Marin, Miguel Angel;
Peña, Ruth;
Pelletier, Adam;
Talla, Aarthi;
Sharma, Ashish;
Dalmau, Judith;
Santos, José Ramón;
Sékaly, Rafick-Pierre;
Clotet, Bonaventura;
Prado, Julia G.

Publication type:

Article

Regulatory T Cell Phenotype Related to Cytokine Expression Patterns in Post‐COVID‐19 Pulmonary Fibrosis and Idiopathic Pulmonary Fibrosis.

Published in:

Immunity, Inflammation & Disease, 2025, v. 13, n. 1, p. 1, doi. 10.1002/iid3.70123

By:

Gangi, Sara;
Bergantini, Laura;
Paggi, Irene;
Spalletti, Marco;
Cameli, Paolo;
Bargagli, Elena;
d'Alessandro, Miriana

Publication type:

Article

Intrahepatic CD161hiCD8+T Cell Recruitment Has a Pathogenetic Potential in Chronic HBV Infection.

Published in:

Immunity, Inflammation & Disease, 2025, v. 13, n. 1, p. 1, doi. 10.1002/iid3.70118

By:

Li, Jianfei;
Liu, Qian;
Duan, Wanlu;
Duan, Zhi;
Liu, Futing;
Ruan, Mengqi;
Zong, Qiyin;
Zhang, Hao;
Zhou, Qiang;
Wang, Qin

Publication type:

Article

B7‐H3 promotes nasopharyngeal carcinoma progression by regulating CD8+ T cell exhaustion.

Published in:

Immunity, Inflammation & Disease, 2024, v. 12, n. 9, p. 1, doi. 10.1002/iid3.70005

By:

Ma, Zhaoen;
Chen, Gui;
Li, Hao;
Yang, Saixuan;
Xu, Yali;
Pan, Bolin;
Lai, Wuping;
Chen, Guangui;
Liao, Wenjing;
Zhang, Xiaowen

Publication type:

Article

Adenosine Generated by Regulatory T Cells Induces CD8+ T Cell Exhaustion in Gastric Cancer through A2aR Pathway.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/4093214

By:

Shi, Linsen;
Feng, Min;
Du, Shangce;
Wei, Xu;
Song, Hu;
Yixin, Xu;
Song, Jun;
Wenxian, Guan

Publication type:

Article

PD-1 and LAG-3 dual blockade: emerging mechanisms and potential therapeutic prospects in cancer.

Published in:

Cancer Biology & Medicine, 2024, v. 21, n. 11, p. 970, doi. 10.20892/j.issn.2095-3941.2024.0436

By:

Xiangyu Qiu;
Zhaoan Yu;
Xiaoqing Lu;
Xin Jin;
Jinrong Zhu;
Rongxin Zhang

Publication type:

Article

Revolutionizing tumor immunotherapy: unleashing the power of progenitor exhausted T cells.

Published in:

Cancer Biology & Medicine, 2024, v. 21, n. 6, p. 499, doi. 10.20892/j.issn.2095-3941.2024.0105

By:

Zhang Fang;
Xinyi Ding;
Hao Huang;
Hongwei Jiang;
Jingting Jiang;
Xiao Zheng

Publication type:

Article

Mechanism and effects of extramedullary hematopoiesis on anti-tumor immunity.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 7, p. 477, doi. 10.20892/j.issn.2095-3941.2023.0203

By:

Zefang Chen;
Xinyu Cheng;
Li Yang;
Xiaoming Cheng;
Bo Zhu;
Haixia Long

Publication type:

Article

Reversing immunosuppression in the tumor microenvironment of fibrolamellar carcinoma via PD-1 and IL-10 blockade.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55593-6

By:

Daniel, S. K.;
Sullivan, K. M.;
Dickerson, L. K.;
van den Bijgaart, R. J. E.;
Utria, A. F.;
Labadie, K. P.;
Kenerson, H. L.;
Jiang, X.;
Smythe, K. S.;
Campbell, J. S.;
Pierce, R. H.;
Kim, T. S.;
Riehle, K. J.;
Yeung, R. S.;
Carter, J. A.;
Barry, K. C.;
Pillarisetty, V. G.

Publication type:

Article

Cross-talk between disulfidptosis and immune check point genes defines the tumor microenvironment for the prediction of prognosis and immunotherapies in glioblastoma.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-52128-x

By:

Zhou, Yanjun;
Qin, Xue;
Hu, Qunchao;
Qin, Shaolei;
Xu, Ran;
Gu, Ke;
Lu, Hua

Publication type:

Article

T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer's disease.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42708-8

By:

Grayson, Jason M.;
Short, Samantha M.;
Lee, C. Jiah;
Park, Nuri;
Marsac, Caitlyn;
Sette, Alessandro;
Lindestam Arlehamn, Cecillia S.;
Leng, Xiaoyan I.;
Lockhart, Samuel N.;
Craft, Suzanne

Publication type:

Article

Identification and validation of tumor microenvironment-related signature for predicting prognosis and immunotherapy response in patients with lung adenocarcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40980-2

By:

Li, Chunhong;
Yuan, Yixiao;
Jiang, Xiulin;
Wang, Qiang

Publication type:

Article

The identification of genes associated T-cell exhaustion and construction of prognostic signature to predict immunotherapy response in lung adenocarcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40662-z

By:

Wu, Yahua;
Du, Bin;
Lin, Mingqiang;
Ji, Xiaohui;
Lv, Chengliu;
Lai, Jinhuo

Publication type:

Article

An immunomodulating peptide with potential to suppress tumour growth and autoimmunity.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47229-y

By:

Agrez, Michael;
Chandler, Christopher;
Thurecht, Kristofer J.;
Fletcher, Nicholas L.;
Liu, Feifei;
Subramaniam, Gayathri;
Howard, Christopher B.;
Blyth, Benjamin;
Parker, Stephen;
Turner, Darryl;
Rzepecka, Justyna;
Knox, Gavin;
Nika, Anastasia;
Hall, Andrew M.;
Gooding, Hayley;
Gallagher, Laura

Publication type:

Article

T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer's disease.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42708-8

By:

Grayson, Jason M.;
Short, Samantha M.;
Lee, C. Jiah;
Park, Nuri;
Marsac, Caitlyn;
Sette, Alessandro;
Lindestam Arlehamn, Cecillia S.;
Leng, Xiaoyan I.;
Lockhart, Samuel N.;
Craft, Suzanne

Publication type:

Article

Identification and validation of tumor microenvironment-related signature for predicting prognosis and immunotherapy response in patients with lung adenocarcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40980-2

By:

Li, Chunhong;
Yuan, Yixiao;
Jiang, Xiulin;
Wang, Qiang

Publication type:

Article

The identification of genes associated T-cell exhaustion and construction of prognostic signature to predict immunotherapy response in lung adenocarcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40662-z

By:

Wu, Yahua;
Du, Bin;
Lin, Mingqiang;
Ji, Xiaohui;
Lv, Chengliu;
Lai, Jinhuo

Publication type:

Article