Works about SYNUCLEINS

Results: 875

Electrochemical Detection of Interaction Between α-Synuclein and Clioquinol.

Published in:

Electroanalysis, 2015, v. 27, n. 6, p. 1436, doi. 10.1002/elan.201500044

By:

Cheng, Xin R.;
Kerman, Kagan

Publication type:

Article

intestinal luminal sources of α-synuclein: a gastroenterologist perspective.

Published in:

Nutrition Reviews, 2022, v. 80, n. 2, p. 282, doi. 10.1093/nutrit/nuab024

By:

Lerner, Aaron

Publication type:

Article

A Plant Model of α-Synucleinopathy: Expression of α-Synuclein A53T Variant in Hairy Root Cultures Leads to Proteostatic Stress and Dysregulation of Iron Metabolism.

Published in:

Applied Biosciences, 2024, v. 3, n. 2, p. 233, doi. 10.3390/applbiosci3020016

By:

Kurepa, Jasmina;
Bruce, Kristen A.;
Gerhardt, Greg A.;
Smalle, Jan A.

Publication type:

Article

HEALTH AND HUMAN SCIENCES: Developmental Atrazine Exposure Modifies Expression of Synucleins.

Published in:

Journal of Purdue Undergraduate Research, 2023, v. 13, p. 113, doi. 10.7771/2158-4052.1643

By:

Akoro, Isabelle

Publication type:

Article

Plasma pS129-α-Synuclein Is a Surrogate Biofluid Marker of Motor Severity and Progression in Parkinson's Disease.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1601, doi. 10.3390/jcm8101601

By:

Lin, Chin-Hsien;
Liu, Huei-Chun;
Yang, Shieh-Yueh;
Yang, Kai-Chien;
Wu, Chau-Chung;
Chiu, Ming-Jang

Publication type:

Article

α-Synuclein Expression in the Mouse Cerebellum Is Restricted to VGluT1 Excitatory Terminals and Is Enriched in Unipolar Brush Cells.

Published in:

Cerebellum, 2015, v. 14, n. 5, p. 516, doi. 10.1007/s12311-015-0673-9

By:

Lee, Sun;
Sillitoe, Roy;
Silva, Coralie;
Martina, Marco;
Sekerkova, Gabriella

Publication type:

Article

Atomic force microscopy based nanoassay: a new method to study α-Synuclein-dopamine bioaffinity interactions.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05366

By:

Corvaglia, Stefania;
Sanavio, Barbara;
Enriquez, Rolando P. Hong;
Sorce, Barbara;
Bosco, Alessandro;
Scaini, Denis;
Sabella, Stefania;
Pompa, Pier Paolo;
Scoles, Giacinto;
Casalis, Loredana

Publication type:

Article

Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00377

By:

Li, Tao;
Feng, Yang;
Yang, Ruixin;
Wu, Leitao;
Li, Ruru;
Huang, Lu;
Yang, Qian;
Chen, Jianzong

Publication type:

Article

GYY4137, an H<sub>2</sub>S Slow-Releasing Donor, Prevents Nitrative Stress and α-Synuclein Nitration in an MPTP Mouse Model of Parkinson's Disease.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00741

By:

Xiaoou Hou;
Yuqing Yuan;
Yulan Sheng;
Baoshi Yuan;
Yali Wang;
Jiyue Zheng;
Chun-Feng Liu;
Xiaohu Zhang;
Li-Fang Hu

Publication type:

Article

Correlations of erythrocytic oligomer α-synuclein levels with age, sex and clinical variables in patients with Parkinson's disease.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1437622

By:

Zhe Lu;
Xiaohan Yu;
Pengjie Li;
Yiming Wang;
Yeyun Deng;
Xin Li;
Chaodong Wang;
Shun Yu

Publication type:

Article

Cognitive dysfunction in animal models of human lewy-body dementia.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1369733

By:

Haikal, Caroline;
Winston, Graham M.;
Kaplitt, Michael G.

Publication type:

Article

Emerging perspectives on precision therapy for Parkinson's disease: multidimensional evidence leading to a new breakthrough in personalized medicine.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1417515

By:

Qiaoli Wang;
Xuan Gu;
Le Yang;
Yan Jiang;
Jiao Zhang;
Jinting He

Publication type:

Article

Cathepsin-mediated regulation of alpha-synuclein in Parkinson's disease: a Mendelian randomization study.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1394807

By:

Liyu Lin;
Zilun Wu;
Haocheng Luo;
Yunxuan Huang

Publication type:

Article

Metabolic energy decline coupled dysregulation of catecholamine metabolism in physiologically highly active neurons: implications for selective neuronal death in Parkinson's disease.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1339295

By:

Wimalasena, Kandatege;
Adetuyi, Oluwatosin;
Eldani, Maya

Publication type:

Article

Trends and hotspots in non-motor symptoms of Parkinson's disease: a 10-year bibliometric analysis.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1335550

By:

Xuefeng Li;
Chunhai Chen;
Ting Pan;
Xue Zhou;
Xiaozhou Sun;
Ziyang Zhang;
Dalong Wu;
Xinhua Chen

Publication type:

Article

Research progress on the cannabinoid type-2 receptor and Parkinson's disease.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2023.1298166

By:

Xiaoqi Yu;
Yi Jia;
Yuan Dong

Publication type:

Article

Treatment of Parkinson’s disease with biologics that penetrate the blood–brain barrier via receptor-mediated transport.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1276376

By:

Pardridge, William M.

Publication type:

Article

CCL5 promotes LFA-1 expression in Th17 cells and induces LCK and ZAP70 activation in a mouse model of Parkinson's disease.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1250685

By:

Jingwei Zhao;
Ke An;
Zhijuan Mao;
Yi Qu;
Danlei Wang;
Jiangting Li;
Zhe Min;
Zheng Xue

Publication type:

Article

Risk of hospitalization in synucleinopathies and impact of psychosis.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1274821

By:

Piat, Capucine;
Mullan, Aidan F.;
Stang, Cole D.;
Hajeb, Mania;
Camerucci, Emanuele;
Turcano, Pierpaolo;
Martin, Peter R.;
Bower, James H.;
Savica, Rodolfo

Publication type:

Article

Global trends and prospects about synaptic plasticity in Alzheimer's disease: a bibliometric analysis.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1234719

By:

Yingying Zhang;
Junyao Zhang;
Yinuo Wang;
Junyan Yao

Publication type:

Article

CSF metabolites associated with biomarkers of Alzheimer's disease pathology.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1214932

By:

Ruocheng Dong;
Qiongshi Lu;
Kang, Hyunseung;
Suridjan, Ivonne;
Kollmorgen, Gwendlyn;
Wild, Norbert;
Deming, Yuetiva;
Van Hulle, Carol A.;
Anderson, Rozalyn M.;
Zetterberg, Henrik;
Blennow, Kaj;
Carlsson, Cynthia M.;
Asthana, Sanjay;
Johnson, Sterling C.;
Engelman, Corinne D.

Publication type:

Article

Uric acid regulates α-synuclein transmission in Parkinsonian models.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1117491

By:

Yu Jin Shin;
Yeon Ju Kim;
Ji Eun Lee;
Yi Seul Kim;
Jung Wook Lee;
HyeonJeong Kim;
Jin Young Shin;
Phil Hyu Lee

Publication type:

Article

Altered sleep and neurovascular dysfunction in alpha-synucleinopathies: the perfect storm for glymphatic failure.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1251755

By:

Buongiorno, Mariateresa;
Marzal, Clara;
Fernandez, Manel;
Cullell, Natalia;
de Mena, Lorena;
Sánchez-Benavides, Gonzalo;
de la Sierra, Alejandro;
Krupinski, Jerzy;
Yaroslau Compta

Publication type:

Article

Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1179086

By:

Fagen, Sara J.;
Burgess, Jeremy D.;
Lim, Melina J.;
Amerna, Danilyn;
Kaya, Zeynep B.;
Faroqi, Ayman H.;
Perisetla, Priyanka;
DeMeo, Natasha N.;
Stojkovska, Iva;
Quiriconi, Drew J.;
Mazzull, Joseph R.;
Delenclos, Marion;
Boschen, Suelen L.;
McLean, Pamela J.

Publication type:

Article

Distinct amyloid-dependent patterns of nigra dopamine depletion in Lewy body diseases.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1196602

By:

Kyoungwon Baik;
Jungho Cha;
Mincheol Park;
Younggun Lee;
Seok Jong Chung;
Han Soo Yoo;
Sohn, Young H.;
Phil Hyu Lee

Publication type:

Article

The ANeED study – ambroxol in new and early dementia with Lewy bodies (DLB): protocol for a phase IIa multicentre, randomised, double-blinded and placebo-controlled trial.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1163184

By:

Chwiszczuk, Luiza Jadwiga;
Breitve, Monica Haraldseid;
Kirsebom, Bjørn-Eivind Bordewick;
Selnes, Per;
Fløvig, John Chr.;
Knapskog, Anne-Brita;
Skogseth, Ragnhild E.;
Hubbers, Jessica;
Holst-Larsen, Elin;
Rongve, Arvid

Publication type:

Article

Estimated glomerular filtration rate is a biomarker of cognitive impairment in Parkinson's disease.

Published in:

Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1130833

By:

Yi Qu;
Qi-Xiong Qin;
Dan-Lei Wang;
Jiang-Ting Li;
Jing-Wei Zhao;
Ke An;
Jing-Yi Li;
Zhi-Juan Mao;
Zhe Min;
Yong-Jie Xiong;
Zheng Xue

Publication type:

Article

Motor and non-motor symptoms in AAV-mediated alpha-synuclein overexpression model of PD in rats.

Published in:

2018

By:

Çınar, Elif;
Çakmaklı, Gül Yalçın;
Tel, Banu Cahide;
Topcuoğlu, Esen Saka;
Elibol, Bülent

Publication type:

Abstract

Accumulation of α-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers.

Published in:

Neurology Research International, 2017, p. 1, doi. 10.1155/2017/5952149

By:

Solmaz, Volkan;
Köse Özlece, Hatice;
Eroglu, Hüseyin Avni;
Aktuğ, Hüseyin;
Erbaş, Oytun;
Taşkıran, Dilek

Publication type:

Article

Effect of chemokine CC ligand 2 (CCL2) on α-synuclein-induced microglia proliferation and neuronal apoptosis.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 5, p. 4213, doi. 10.3892/mmr.2018.9468

By:

Zhang, Lijun;
Ma, Pengju;
Guan, Qingkai;
Meng, Lei;
Su, Linlin;
Wang, Lina;
Yuan, Bin

Publication type:

Article

α-synuclein induces apoptosis of astrocytes by causing dysfunction of the endoplasmic reticulum-Golgi compartment.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 322, doi. 10.3892/mmr.2018.9002

By:

Liu, Mei;
Qin, Lixia;
Wang, Lili;
Tan, Jieqiong;
Zhang, Hainan;
Tang, Jianguang;
Shen, Xiangmin;
Tan, Liming;
Wang, Chunyu

Publication type:

Article

DL‑3‑n‑butylphthalide reduces microglial activation in lipopolysaccharide‑induced Parkinson's disease model mice.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 3, p. 3884, doi. 10.3892/mmr.2017.8332

By:

ChEN, Yuhua;
Jiang, Mujun;
Li, Li;
Ye, Ming;
Yu, Meiling;
Zhang, Lina;
Ge, Bobo;
Xu, WENfang;
Wei, Daoxiang

Publication type:

Article

Time-course behavioral features are correlated with Parkinson's disease-associated pathology in a 6-hydroxydopamine hemiparkinsonian rat model.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 2, p. 3356, doi. 10.3892/mmr.2017.8277

By:

Su, Rui-Jun;
Zhen, Jun-Li;
Wang, Wei;
Zhang, Jian-Liang;
Zheng, Yan;
Wang, Xiao-Min

Publication type:

Article

c-Jun N-terminal kinase 3 signalling serves a potential role as a biomarker for determining the pathogenesis of Parkinson's disease.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 2, p. 3255, doi. 10.3892/mmr.2017.8244

By:

Yang, Xiu-Li;
Gao, Chun-Mei

Publication type:

Article

Neuroprotective effect of chondroitin sulfate on SH-SY5Y cells overexpressing wild-type or A53T mutant α-synuclein.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 6, p. 8721, doi. 10.3892/mmr.2017.7725

By:

CHUANXIA JU;
JIANJUN GAO;
LIN HOU;
LEI WANG;
FANG ZHANG;
FUSHENG SUN;
TINGTING ZHANG;
PINGPING XU;
ZHENYAN SHI;
FANG HU;
CONGXIAO ZHANG

Publication type:

Article

Identification of key genes and pathways in Parkinson's disease through integrated analysis.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 4, p. 3769, doi. 10.3892/mmr.2017.7112

By:

JINGRU WANG;
YINING LIU;
TUANZHI CHEN

Publication type:

Article

Heat shock protein 70 induction by glutamine increases the α-synuclein degradation in SH-SY5Y neuroblastoma cells.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 4, p. 5524, doi. 10.3892/mmr.2015.4027

By:

JIA YANG;
YANMEI ZHANG;
SHIGANG ZHAO;
ZHELIN ZHANG;
XIUQING TONG;
FANG WEI;
ZUNENG LU

Publication type:

Article

Synuclein-γ promotes migration of MCF7 breast cancer cells by activating extracellular-signal regulated kinase pathway and breaking cell-cell junctions.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3795, doi. 10.3892/mmr.2015.3799

By:

QING ZHUANG;
CAIYUN LIU;
LIKE QU;
CHENGCHAO SHOU

Publication type:

Article

Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 3, p. 1655, doi. 10.3892/mmr.2014.3011

By:

DANMEI LAN;
WENZHAO WANG;
JIANHUA ZHUANG;
ZHONGXIN ZHAO

Publication type:

Article

A porous silicon immunoassay platform for fluorometric determination of α-synuclein in human cerebrospinal fluid.

Published in:

Microchimica Acta, 2014, v. 181, n. 9/10, p. 1143, doi. 10.1007/s00604-014-1180-2

By:

Lee, Sangwook;
Silajdžić, Edina;
Yang, Hon;
Björkqvist, Maria;
Kim, Soyon;
Jeong, Ok;
Hansson, Oskar;
Laurell, Thomas

Publication type:

Article

Quantitative, Label-Free Detection of the Aggregation of α-Synuclein Using Microcantilever Arrays Operated in a Liquid Environment.

Published in:

Journal of Sensors, 2012, p. 1, doi. 10.1155/2012/874086

By:

Jensen, Jason;
Farina, Margherita;
Zuccheri, Giampaolo;
Grange, Wilfried;
Hegner, Martin

Publication type:

Article

α-Synuclein in the olfactory system in Parkinson's disease: role of neural connections on spreading pathology.

Published in:

Brain Structure & Function, 2014, v. 219, n. 5, p. 1513, doi. 10.1007/s00429-013-0651-2

By:

Ubeda-Bañon, Isabel;
Saiz-Sanchez, Daniel;
Rosa-Prieto, Carlos;
Martinez-Marcos, Alino

Publication type:

Article

α-Synuclein in the olfactory system of a mouse model of Parkinson's disease: correlation with olfactory projections.

Published in:

Brain Structure & Function, 2012, v. 217, n. 2, p. 447, doi. 10.1007/s00429-011-0347-4

By:

Ubeda-Bañon, Isabel;
Saiz-Sanchez, Daniel;
Rosa-Prieto, Carlos;
Martinez-Marcos, Alino

Publication type:

Article

Icariin reduces α-synuclein over-expression by promoting α-synuclein degradation.

Published in:

Age (0161-9152), 2015, v. 37, n. 4, p. 1, doi. 10.1007/s11357-015-9811-z

By:

Zhang, Lan;
Shen, Cong;
Chu, Jin;
Liu, Ying;
Li, Yali;
Zhang, Li;
Li, Lin

Publication type:

Article

New Frontiers in Parkinson's Disease: From Genetics to the Clinic.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 44, p. 9375, doi. 10.1523/JNEUROSCI.1666-18.2018

By:

Shihabuddin, Lamya S.;
Brundin, Patrik;
Greenamyre, J. Timothy;
Stephenson, Diane;
Sardi, S. Pablo

Publication type:

Article

A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 43, p. 9286, doi. 10.1523/JNEUROSCI.0254-18.2018

By:

Rousseaux, Maxime W. C.;
Vázquez-Vélez, Gabriel E.;
Al-Ramahi, Ismael;
Hyun-Hwan Jeong;
Bajić, Aleksandar;
Revelli, Jean-Pierre;
Hui Ye;
Phan, Emily T.;
Deger, Jennifer M.;
Perez, Alma M.;
Kim, Ji-Yoen;
Lavery, Laura A.;
Qikia Xu;
Li, Mamie Z.;
Hyojin Kang;
Kim, Jean J.;
Shulman, Joshua M.;
Westbrook, Thomas F.;
Elledge, Stephen J.;
Zhandong Liu

Publication type:

Article

Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 1000, doi. 10.1523/JNEUROSCI.1170-17.2017

By:

Rockenstein, Edward;
Mante, Michael;
Florio, Jazmin;
Adame, Anthony;
Trinh, Ivy;
Overk, Cassia;
Rissman, Robert A.;
Changyoun Kim;
Masliah, Eliezer;
Ostroff, Gary;
Dikengil, Fusun;
Rus, Florentina

Publication type:

Article

Wild-Type Monomeric α:-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 25, p. 6043, doi. 10.1523/JNEUROSCI.0179-17.2017

By:

Kohgaku Eguchi;
Zacharie Taoufiq;
Thorn-Seshold, Oliver;
Trauner, Dirk;
Hasegawa, Masato;
Takahashi, Tomoyuki

Publication type:

Article

Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 24, p. 5870, doi. 10.1523/JNEUROSCI.2705-16.2017

By:

Henderson, Michael X.;
Charlotte Hiu-Yan Chung;
Riddle, Dawn M.;
Bin Zhang;
Gathagan, Ronald J.;
Seeholzer, Steven H.;
Trojanowski, John Q.;
Lee, Virginia M. Y.

Publication type:

Article

Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 1, p. 47, doi. 10.1523/JNEUROSCI.1079-16.2017

By:

Lasser-Katz, Efrat;
Wei-Hua Chiu;
Goldberg, Joshua A.;
Simchovitz, Alon;
Soreq, Hermona;
Oertel, Wolfgang H.;
Sharon, Ronit;
Roeper, Jochen

Publication type:

Article