Works matching DE "SUPPRESSORS of cytokine signaling"

Results: 496

The Neglected Suppressor of Cytokine Signalling (SOCS): SOCS4-7.

Published in:

Inflammation, 2025, v. 48, n. 4, p. 1607, doi. 10.1007/s10753-024-02163-7

By:

Herrera-Uribe, Juber;
Convery, Orla;
ALmohammadi, Daniah;
Weinberg, Fabienne Ingrid;
Stevenson, Nigel J.

Publication type:

Article

Immunotherapy-Based Strategies for Treatment of Type 1 Diabetes.

Published in:

Hormone Research in Paediatrics, 2025, v. 98, n. 4, p. 425, doi. 10.1159/000542002

By:

Jacobsen, Laura M.;
Schatz, Desmond

Publication type:

Article

Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00515-3

By:

Sun, Ling;
He, Lingyan;
Pan, Hai-Hua;
Zhai, Chang-Lin

Publication type:

Article

Research progress of SOCS in autoimmune diseases: mechanisms and therapeutic implications.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1604271

By:

Cui, Rongqi;
Zhang, Jing

Publication type:

Article

Interleukin-24 as a Pulmonary Target Cytokine in Bronchopulmonary Dysplasia.

Published in:

Cell Biochemistry & Biophysics, 2021, v. 79, n. 2, p. 311, doi. 10.1007/s12013-021-00968-z

By:

Gao, Ruiwei;
Li, Zhihua;
Ai, Danyang;
Ma, Jinshuai;
Chen, Chao;
Liu, Xiuxiang

Publication type:

Article

The Role of Phthalocyanine-Gold Nanoconjugates (Pc-Au NCs) in Ameliorating the Hepatic and Renal Toxicity-Induced by Silver Nanoparticles (Ag NPs) in Male Rats.

Published in:

Biological Trace Element Research, 2024, v. 202, n. 12, p. 5637, doi. 10.1007/s12011-024-04209-1

By:

Abd Elhameed, Heba A. H.;
Attia, Mai S.;
Mohamed, Amira A. A.;
Alexeree, Shaimaa M. I.;
Behery, Eman I. El;
Alagawany, Mahmoud;
Farag, Mayada R.;
Di Cerbo, Alessandro;
Azzam, Mahmoud M.;
Mawed, Suzan Attia

Publication type:

Article

Lithium Chloride Promotes Milk Protein and Fat Synthesis in Bovine Mammary Epithelial Cells via HIF-1α and β-Catenin Signaling Pathways.

Published in:

Biological Trace Element Research, 2023, v. 201, n. 1, p. 180, doi. 10.1007/s12011-022-03131-8

By:

Zong, Jinxin;
Shen, Jinglin;
Liu, Xinlu;
Liu, Jiayi;
Zhang, Jing;
Zhou, Changhai;
Fan, Yating;
Jin, Yongcheng

Publication type:

Article

The Role of Cell Growth-Related Gene Copy Number Variation in Autoimmune Thyroid Disease.

Published in:

Biological Trace Element Research, 2020, v. 195, n. 2, p. 409, doi. 10.1007/s12011-019-01880-7

By:

Guan, Yunfeng;
Liu, Lixiang;
Jia, Qingzhen;
Jin, Xing;
Pang, Yi;
Meng, Fangang;
Zhang, Xiaoye;
Shen, Hongmei

Publication type:

Article

Suppressors of Cytokine Signaling 3 Expression in Eosinophils: Regulation by PGE<sub>2</sub> and Th2 Cytokines.

Published in:

Clinical & Developmental Immunology, 2011, p. 1, doi. 10.1155/2011/917015

By:

López, Esther;
Zafra, María Paz;
Sastre, Beatriz;
Gámez, Cristina;
Fernández-Nieto, Mar;
Sastre, Joaquín;
Lahoz, Carlos;
Quirce, Santiago;
Del Pozo, Victoria

Publication type:

Article

MicroRNA-155 Participates in Smoke-Inhalation-Induced Acute Lung Injury through Inhibition of SOCS-1.

Published in:

Molecules, 2020, v. 25, n. 5, p. 1022, doi. 10.3390/molecules25051022

By:

Zhang, Yue;
Xie, Yifang;
Zhang, Leifang;
Zhao, Hang

Publication type:

Article

SOCS3-Mediated Blockade Reveals Major Contribution of JAK2/STAT5 Signaling Pathway to Lactation and Proliferation of Dairy Cow Mammary Epithelial Cells in Vitro.

Published in:

Molecules, 2013, v. 18, n. 10, p. 12987, doi. 10.3390/molecules181012987

By:

Yu-Ling Huang;
Feng Zhao;
Chao-Chao Luo;
Xia Zhang;
Yu Si;
Zhe Sun;
Li Zhang;
Qing-Zhang Li;
Xue-Jun Gao

Publication type:

Article

Cardiac Ablation of SOCS3 Aggravates DOCA-Salt-Induced Hypertrophic Remodeling by Activation of Gp130-Dependent Signaling in Mice.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 47, n. 1, p. 140, doi. 10.1159/000489757

By:

Shuang Liu;
Li-Xin Liu;
Yun-Long Zhang;
Song Lai;
Yun-Peng Xie;
Nan-Nan Li;
Hong-Xia Wang;
Yun-Long Xia;
Ying Liu;
Hui-Hua Li

Publication type:

Article

IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 42, n. 5, p. 1961, doi. 10.1159/000479836

By:

Lv, Ran;
Zhao, Jinning;
Lei, Min;
Xiao, Dongju;
Yu, Yijin;
Xie, Junran

Publication type:

Article

MicroRNA-155 Promotes Atherosclerosis Inflammation via Targeting SOCS1.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2015, v. 36, n. 4, p. 1371, doi. 10.1159/000430303

By:

Yang, Yang;
Yang, Lixia;
Liang, Xing;
Zhu, Guofu

Publication type:

Article

Early Secreted Antigen ESAT-6 of Mycobacterium Tuberculosis Promotes Apoptosis of Macrophages via Targeting the MicroRNA155-SOCS1 Interaction.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2015, v. 35, n. 4, p. 1276, doi. 10.1159/000373950

By:

Yang, Shaojun;
Li, Fake;
Jia, Shuangrong;
Zhang, Kejun;
Jiang, Wenbing;
Shang, Ya;
Chang, Kai;
Deng, Shaoli;
Chen, Ming

Publication type:

Article

Zika Virus-Induction of the Suppressor of Cytokine Signaling 1/3 Contributes to the Modulation of Viral Replication.

Published in:

Pathogens, 2020, v. 9, n. 3, p. 163, doi. 10.3390/pathogens9030163

By:

Seong, Rak-Kyun;
Lee, Jae Kyung;
Shin, Ok Sarah

Publication type:

Article

Regulation of Staphylococcal Enterotoxin-Induced Inflammation in Spleen Cells from Diabetic Mice by Polyphenols.

Published in:

Microorganisms, 2023, v. 11, n. 4, p. 1039, doi. 10.3390/microorganisms11041039

By:

Shimamura, Yuko;
Noaki, Rina;
Oura, Yukino;
Ichikawa, Kenya;
Kan, Toshiyuki;
Masuda, Shuichi

Publication type:

Article

Lack of association between SOCS3 and SOCS7 polymorphisms and psoriasis.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 10, p. 1, doi. 10.1002/iid3.695

By:

Özçep, Merve;
Atsü, Nilhan;
Solak, Nilgün;
Çelik, Sevim Karakaş

Publication type:

Article

Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation.

Published in:

Immunity, Inflammation & Disease, 2017, v. 5, n. 3, p. 336, doi. 10.1002/iid3.171

By:

Shaw, Elisabeth J.;
Smith, Emily E.;
Whittingham‐Dowd, Jayde;
Hodges, Matthew D.;
Else, Kathryn J.;
Rigby, Rachael J.

Publication type:

Article

miR-19b downregulates intestinal SOCS3 to reduce intestinal inflammation in Crohn's disease.

Published in:

Scientific Reports, 2015, p. 10397, doi. 10.1038/srep10397

By:

Cheng, Xiuqin;
Zhang, Xiaofei;
Su, Jiewen;
Zhang, Yingdi;
Zhou, Weimei;
Zhou, Jun;
Wang, Cheng;
Liang, Hongwei;
Chen, Xi;
Shi, Ruihua;
Zen, Ke;
Zhang, Chen-Yu;
Zhang, Hongjie

Publication type:

Article

SOCS3 Acts as an Onco-immunological Biomarker With Value in Assessing the Tumor Microenvironment, Pathological Staging, Histological Subtypes, Therapeutic Effect, and Prognoses of Several Types of Cancer.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.881801

By:

Dai, Lirui;
Tao, Yiran;
Shi, Zimin;
Liang, Wulong;
Hu, Weihua;
Xing, Zhe;
Zhou, Shaolong;
Guo, Xuyang;
Fu, Xudong;
Wang, Xinjun

Publication type:

Article

Anti-Tumoral Effect and Action Mechanism of Exosomes Derived From Toxoplasma gondii -Infected Dendritic Cells in Mice Colorectal Cancer.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.870528

By:

Zhu, Shilan;
Lu, Jinmiao;
Lin, Zhibing;
Abuzeid, Asmaa M. I.;
Chen, Xiaoyu;
Zhuang, Tingting;
Gong, Haiyan;
Mi, Rongsheng;
Huang, Yan;
Chen, Zhaoguo;
Li, Guoqing

Publication type:

Article

A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo : implications for recurrent uveitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1513157

By:

Stafford, Lauren Stewart;
Plummer, Caryn E.;
Smith, W. Clay;
Gibson, Daniel J.;
Sharma, Jatin;
Vicuna, Valeria;
Diakite, Sisse;
Larkin III, Joseph

Publication type:

Article

Unravelling the druggability and immunological roles of the SOCS-family proteins.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1449397

By:

Lynch, Dylan M.;
Forrester, Beth;
Webb, Thomas;
Ciulli, Alessio

Publication type:

Article

A loss of function mutation in SOCS2 results in increased inflammatory response of macrophages to TLR ligands and Staphylococcus aureus.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1397330

By:

Guzylack-Piriou, Laurence;
Gausseres, Blandine;
Tasca, Christian;
Hassel, Chervin;
Tabouret, Guillaume;
Foucras, Gilles

Publication type:

Article

Corneal application of SOCS1/3 peptides for the treatment of eye diseases mediated by inflammation and oxidative stress.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1416181

By:

Ahmed, Chulbul M.;
Johnson, Howard M.;
Lewin, Alfred S.

Publication type:

Article

SOCS1 is a critical checkpoint in immune homeostasis, inflammation and tumor immunity.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1419951

By:

Bidgood, Grace M.;
Keating, Narelle;
Doggett, Karen;
Nicholson, Sandra E.

Publication type:

Article

One gene to rule them all -- clinical perspectives of a potent suppressor of cytokine signaling -- SOCS1.

Published in:

Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1385190

By:

Körholz, Julia;
Lan-Sun Chen;
Strauss, Timmy;
Schuetz, Catharina;
Dalpke, Alexander H.

Publication type:

Article

Integrative Analyses of mRNA Expression Profile Reveal SOCS2 and CISH Play Important Roles in GHR Mutation-Induced Excessive Abdominal Fat Deposition in the Sex-Linked Dwarf Chicken.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.610605

By:

Chen, Genghua;
Chen, Jiahui;
Wu, Jingwen;
Ren, Xueyi;
Li, Limin;
Lu, Shiyi;
Cheng, Tian;
Tan, Liangtian;
Liu, Manqing;
Luo, Qingbin;
Liang, Shaodong;
Nie, Qinghua;
Zhang, Xiquan;
Luo, Wen

Publication type:

Article

Aberrant expression of suppressor of cytokine signaling (SOCS) molecules contributes to the development of allergic diseases.

Published in:

Clinical & Experimental Allergy, 2023, v. 53, n. 11, p. 1147, doi. 10.1111/cea.14385

By:

Jafarzadeh, Abdollah;
Chauhan, Prashant;
Nemati, Maryam;
Jafarzadeh, Sara;
Yoshimura, Akihiko

Publication type:

Article

SOCS1 acts as a ferroptosis driver to inhibit the progression and chemotherapy resistance of triple-negative breast cancer.

Published in:

Carcinogenesis, 2023, v. 44, n. 8/9, p. 708, doi. 10.1093/carcin/bgad060

By:

Wang, Yiding;
Pang, Xiaoling;
Liu, Yuexin;
Mu, Guiling;
Wang, Qian

Publication type:

Article

Evaluating the specific STAT3 inhibitor YHO-1701 in ovarian cancer cell lines and patient-derived cell models: efficacy, mechanisms, and therapeutic potential.

Published in:

Journal of Gynecologic Oncology, 2025, v. 36, n. 2, p. 1, doi. 10.3802/jgo.2025.36.e24

By:

Sho Sato;
Takahito Miura;
Aiko Ogasawara;
Daisuke Shintani;
Shogo Yamaguchi;
Hiroaki Inui;
Akiko Yoshinaga;
Masahiko Nishiyama;
Momomi Tsugane;
Kosei Hasegawa

Publication type:

Article

AP2α negatively regulates PDHA1 in cervical cancer cells to promote aggressive features and aerobic glycolysis in vitro and in vivo.

Published in:

Journal of Gynecologic Oncology, 2023, v. 34, n. 5, p. 1, doi. 10.3802/jgo.2023.34.e59

By:

Lijie Zhao;
Rong Geng;
Yi Huang;
Jiping Zhang;
Haiying Cheng;
Cankun Zhou;
Yifeng Wang

Publication type:

Article

SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice.

Published in:

Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03347-y

By:

Sui, Mingxing;
Li, Tuo;
Lu, Hanlan;
Li, Yanhua;
Huang, Juan;
Zhang, Pei;
Wang, Shusen;
Zeng, Li

Publication type:

Article

MicroRNAs Regulate Tumorigenesis by Downregulating SOCS3 Expression: An In silico Approach.

Published in:

Bioinformatics & Biology Insights, 2023, v. 17, p. 1, doi. 10.1177/11779322231193535

By:

Al-Asadi, Sura;
Mansour, Hiba;
Ataimish, Ahmed Jwaid;
Al-Kahachi, Rusul;
Rampurawala, Jamila

Publication type:

Article

Integrative Analysis for Identification of Therapeutic Targets and Prognostic Signatures in Non-Small Cell Lung Cancer.

Published in:

Bioinformatics & Biology Insights, 2022, v. 16, p. 1, doi. 10.1177/11779322221088796

By:

Erkin, Özgür Cem;
Cömertpay, Betül;
Göv, Esra

Publication type:

Article

Antibody-Dependent Enhancement Infection Facilitates Dengue Virus-Regulated Signaling of IL-10 Production in Monocytes.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 11, p. 1, doi. 10.1371/journal.pntd.0003320

By:

Tsai, Tsung-Ting;
Chuang, Yi-Jui;
Lin, Yee-Shin;
Chang, Chih-Peng;
Wan, Shu-Wen;
Lin, Sheng-Hsiang;
Chen, Chia-Ling;
Lin, Chiou-Feng

Publication type:

Article

D-Pinitol Attenuated Ovalbumin-induced Allergic Rhinitis in Experimental Mice via Balancing Th1/Th2 Response.

Published in:

2021

By:

Xiying You;
Xiaopeng Sun;
Junfei Kong;
Jifeng Tian;
Yanping Shi;
Xia Li;
You, Xiying;
Sun, Xiaopeng;
Kong, Junfei;
Tian, Jifeng;
Shi, Yanping;
Li, Xia

Publication type:

journal article

Identification and Expression Analysis of Suppressors of Cytokine Signaling from Spotted Seabass (Lateolabrax maculatus).

Published in:

Aquaculture Research, 2024, p. 1, doi. 10.1155/2024/6611206

By:

Cai, Chuanguo;
Xie, Jiasong;
Gao, Jiaqi;
Qi, Zhitao;
Fan, Ke;
Sun, Zhaosheng;
Lei, Lina;
Gao, Qian

Publication type:

Article

SOCS (Suppressor of Cytokine Signaling) protein as material to enhance the effect of growth hormone in broilers.

Published in:

EurAsian Journal of Biosciences, 2019, v. 13, n. 2, p. 701

By:

Ma'ruf, Anwar;
L., Nunuk Dyah Retno;
Damayanti, Ratna;
Hidajati, Nove;
Atik, M. Gandul

Publication type:

Article

High Intensity Interval Training can Ameliorate Hypothalamic Appetite Regulation in Male Rats with Type 2 Diabetes: The Role of Leptin.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 8, p. 4295, doi. 10.1007/s10571-023-01421-w

By:

Khoramipour, Kayvan;
Rezaei, Maryam Hossein;
Madadizadeh, Elham;
Hosseini, Mahdieh Sadat;
Soltani, Zahra;
Schierbauer, Janis;
Moser, Othmar

Publication type:

Article

Poor stimulation of bovine dendritic cells by Mycobacterium bovis culture supernatant and surface extract is associated with decreased activation of ERK and NF- κ B and higher expression of SOCS1 and 3.

Published in:

Innate Immunity, 2020, v. 26, n. 6, p. 537, doi. 10.1177/1753425920929759

By:

Ihedioha, Olivia;
Potter, Andrew A;
Chen, Jeffrey M

Publication type:

Article

Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00039

By:

Uren, Rachel T.;
Turnley, Ann M.

Publication type:

Article

LINC00668 Modulates SOCS5 Expression Through Competitively Sponging miR-518c-3p to Facilitate Glioma Cell Proliferation.

Published in:

Neurochemical Research, 2020, v. 45, n. 7, p. 1614, doi. 10.1007/s11064-020-02988-2

By:

Liu, Zhenyang;
Wang, Junyu;
Tong, Haibo;
Wang, Xiangyang;
Zhang, Dong;
Fan, Qin

Publication type:

Article

Astragalus Polysaccharide Regulates Proliferation, Migration and Invasion of Lung Cancer Cells via Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathway.

Published in:

Indian Journal of Pharmaceutical Sciences, 2021, v. 83, n. 6, p. 1215, doi. 10.36468/pharmaceutical-sciences.876

By:

CAI, H.;
CAO, J.

Publication type:

Article

TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling.

Published in:

2020

By:

Epstein Shochet, Gali;
Brook, Elizabetha;
Bardenstein-Wald, Becky;
Shitrit, David

Publication type:

journal article

Genes associated with inflammation may serve as biomarkers for the diagnosis of coronary artery disease and ischaemic stroke.

Published in:

Lipids in Health & Disease, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12944-020-01217-7

By:

Zheng, Peng-Fei;
Liao, Fu-Jun;
Yin, Rui-Xing;
Chen, Lu-Zhu;
Li, Hui;
Nie, Rong-Jun;
Wang, Yong;
Liao, Pei-Juan

Publication type:

Article

Ozone alleviates MSU-induced acute gout pain via upregulating AMPK/GAS6/MerTK/SOCS3 signaling pathway.

Published in:

Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04769-1

By:

Fan, Wen;
Liu, Chong;
Chen, Dacai;
Xu, Chenjie;
Qi, Xiuting;
Zhang, Ailin;
Zhu, Xuexian;
Liu, Yujie;
Wang, Lei;
Hao, Lanxiang;
Liu, Wen-Tao;
Hu, Liang

Publication type:

Article

Inhibition of let-7b-5p contributes to an anti-tumorigenic macrophage phenotype through the SOCS1/STAT pathway in prostate cancer.

Published in:

Cancer Cell International, 2020, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12935-020-01563-7

By:

Rong, Jiping;
Xu, Lu;
Hu, Yinying;
Liu, Fan;
Yu, Yanrong;
Guo, Hongyan;
Ni, Xudong;
Huang, Yanqin;
Zhao, Lin;
Wang, Zhigang

Publication type:

Article

Cinnamaldehyde and hesperetin attenuate TNBS‐induced ulcerative colitis in rats through modulation of the JAk2/STAT3/SOCS3 pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 5, p. 1, doi. 10.1002/jbt.22730

By:

Elhennawy, Mayada G.;
Abdelaleem, Eglal A.;
Zaki, Amal A.;
Mohamed, Wafaa R.

Publication type:

Article