Works about SUNITINIB

Results: 281

Repurposing Secukinumab and Dapagliflozin as Candidate Therapies to Mitigate the Renal Toxicity of Sunitinib in Rats Through Suppressing IL‐17‐Mediated Pyroptosis and Promoting Autophagy.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 3, p. 1, doi. 10.1002/jbt.70204

By:

Elrashidy, Rania A.;
Mohamad, Hoda E.;
Aal, Sara M. Abdel;
Mohamed, Samar R.;
Tolba, Sara M.;
Mahmoud, Yasmin K.

Publication type:

Article

Sunitinib suppresses M2 polarization of macrophages in tumor microenvironment to regulate hepatocellular carcinoma progression.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 6, p. 1, doi. 10.1002/jbt.23333

By:

Kong, Yun;
Guo, Li

Publication type:

Article

The efficacy of second-line tyrosine kinase inhibitor for patients with metastatic non-clear cell renal cell carcinoma following first-line immune-oncology combination therapy.

Published in:

World Journal of Urology, 2024, v. 42, n. 1, p. 1, doi. 10.1007/s00345-024-05252-2

By:

Fujita, Kazutoshi;
Matsushita, Yuto;
Toyoda, Shingo;
Kojima, Takahiro;
Yamashita, Shimpei;
Taniguchi, Hisanori;
Monji, Keisuke;
Ishiyama, Ryo;
Tatarano, Shuichi;
Masui, Kimihiko;
Nakamura, Eijiro;
Kaneko, Tomoyuki;
Kitano, Goshi;
Motoshima, Takanobu;
Shiraishi;
Kira, Satoru;
Murashima, Takaya;
Hara, Hiroaki;
Matsumura;
Nishiyama, Naotaka

Publication type:

Article

CT features combined with RECIST 1.1 criteria improve progression assessments of sunitinib-treated gastrointestinal stromal tumors.

Published in:

European Radiology, 2024, v. 34, n. 6, p. 3659, doi. 10.1007/s00330-023-10383-y

By:

Li, Jiazheng;
Huang, Shaoqing;
Zhu, Hui;
Shou, Chunhui;
Lin, Tianyu;
Yin, Xiaonan;
Zhu, Quanjian;
Sun, Dongmei;
Li, Xiaoting;
Shen, Lin;
Li, Jian;
Kou, Youwei;
Zhou, Yongjian;
Zhang, Bo;
Qian, Haoran;
Yu, Jiren;
Zhou, Ye;
Tang, Lei;
Zhang, Xinhua

Publication type:

Article

Nesprin1 Deficiency Is Associated with Poor Prognosis of Renal Cell Carcinoma and Resistance to Sunitinib Treatment.

Published in:

Oncology, 2024, v. 102, n. 10, p. 868, doi. 10.1159/000536539

By:

Fukushima, Takafumi;
Kobatake, Kohei;
Miura, Kento;
Takemoto, Kenshiro;
Yamanaka, Ryoken;
Tasaka, Ryo;
Kohada, Yuki;
Miyamoto, Shunsuke;
Sekino, Yohei;
Kitano, Hiroyuki;
Goto, Keisuke;
Ikeda, Kenichiro;
Goriki, Akihiro;
Hieda, Keisuke;
Kaminuma, Osamu;
Hinata, Nobuyuki

Publication type:

Article

MembIT – A Tool to Calculate Solute Membrane Insertions and Deformations in Molecular Dynamics Simulations.

Published in:

Journal of Computational Biophysics & Chemistry, 2023, v. 22, n. 5, p. 541, doi. 10.1142/S2737416523500254

By:

Suzano, Pedro M. S.;
Pires, Inês D. S.;
Silva, Tomás F. D.;
Oliveira, Nuno F. B.;
Reis, Pedro B. P. S.;
Machuqueiro, Miguel

Publication type:

Article

Individualized surgical treatment in patients with advanced gastrointestinal stromal tumor -- a case series.

Published in:

Oncology in Clinical Practice (2450-1654), 2023, v. 19, n. 5, p. 384, doi. 10.5603/OCP.2023.0023

By:

Pytlos, Jakub;
Pałucki, Jakub;
Lenarcik, Małgorzata;
Pierzankowski, Ireneusz;
Klimczak, Anna;
Olesiński, Tomasz

Publication type:

Article

Evaluation of the effectiveness and tolerability of sunitinib and pazopanib in the first line treatment of metastatic renal cell carcinoma.

Published in:

Oncology in Clinical Practice (2450-1654), 2022, v. 18, n. 4, p. 226, doi. 10.5603/OCP.2021.0033

By:

Ebinç, Senar;
Kalkan, Ziya;
Oruç, Zeynep;
Urakçı, Zuhat;
Küçüköner, Mehmet;
Kaplan, Muhammet Ali;
Işıkdoğan, Abdurrahman

Publication type:

Article

An oncogenic role of lncRNA SNHG1 promotes ATG7 expression and autophagy involving tumor progression and sunitinib resistance of Renal Cell Carcinoma.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02021-3

By:

Tian, Pei;
Wei, Jinxing;
Li, Jing;
Ren, Junkai;
He, Chaohong

Publication type:

Article

基于PD-1/PD-L1 抑制剂联合疗法对比舒尼替尼治疗晚期肾细胞癌安全性和有效性的Meta分析

Published in:

Chinese Journal of Cancer Biotherapy, 2023, v. 30, n. 5, p. 393, doi. 10.3872/j.issn.1007-385x.2023.05.005

By:

方跃华;
周晓燕;
林琴;
林志冰;
林雨虹

Publication type:

Article

The Relationship Between Health-Related Quality of Life and Overall Survival in Patients With Advanced Renal Cell Carcinoma in CheckMate 214.

Published in:

Oncologist, 2024, v. 29, n. 6, p. 511, doi. 10.1093/oncolo/oyae003

By:

Cella, David;
Choueiri, Toni K;
Hamilton, Melissa;
Blum, Steven I;
Ivanescu, Cristina;
Karu, Karl;
Ejzykowicz, Flavia;
Motzer, Robert J

Publication type:

Article

SAMETA: A Phase III study of savolitinib + durvalumab vs sunitinib and durvalumab monotherapy in patients with MET-driven, unresectable, locally advanced/metastatic papillary renal cell carcinoma.

Published in:

Oncologist, 2023, v. 28, p. S11, doi. 10.1093/oncolo/oyad216.018

By:

Chouieri, Toni

Publication type:

Article

Combining Sunitinib and Bevacizumab for the Management of Advanced Renal Cell Carcinoma: A Phase I/II Trial.

Published in:

Oncologist, 2023, v. 28, n. 5, p. e254, doi. 10.1093/oncolo/oyac261

By:

Bazarbashi, Shouki;
Alzahrani, Ahmed;
Aljubran, Ali;
Elshenawy, Mahmoud;
Gad, Ahmed Mostafa;
Maraiki, Fatima;
Alzannan, Noura;
Elhassan, Tusneem;
Badran, Ahmed

Publication type:

Article

Multi-omics and immunogenomics analysis revealed PFKFB3 as a targetable hallmark and mediates sunitinib resistance in papillary renal cell carcinoma: in silico study with laboratory verification.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-024-01808-5

By:

Lu, Zhongwen;
Pan, Yongsheng;
Wang, Songbo;
Wu, Jiajin;
Miao, Chenkui;
Wang, Zengjun

Publication type:

Article

An evaluation of the clinical and treatment features of renal cell carcinoma.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2024, v. 41, n. 2, p. 294, doi. 10.52142/omujecm.41.2.12

By:

MAJIDOVA, Nargiz;
DEMIRAG, Güzin

Publication type:

Article

NETWORK TOXICOLOGY FOR THE CARDIOVASCULAR TOXICITY ANALYSIS OF TYROSINE KINASE INHIBITORS.

Published in:

Journal of Faculty of Pharmacy of Ankara University / Ankara Üniversitesi Eczacilik Fakültesi Dergisi, 2024, v. 48, n. 3, p. 929, doi. 10.33483/jfpau.1478733

By:

KARAKUŞ, Fuat

Publication type:

Article

Neratinib Alone or in Combination with Immune Checkpoint Inhibitors with or without Mammalian Target of Rapamycin Inhibitors in Patients with Fibrolamellar Carcinoma.

Published in:

Liver Cancer (2235-1795), 2025, v. 14, n. 1, p. 58, doi. 10.1159/000540290

By:

Abou-Alfa, Ghassan K.;
Meyer, Tim;
Do, Richard Kinh Gian;
Piha-Paul, Sarina A.;
Light, Joseph S.;
Sherrin, Scott;
Yaqubie, Amin;
O'Neill, Alison Clemens;
Harding, James J.;
Al-Rajabi, Raed;
Denlinger, Crystal S.;
Cano, Pablo;
Cornelius, Albert S.;
O'Reilly, Eileen M.;
DiPrimeo, Daniel;
Eli, Lisa D.;
Gordan, John D.;
Solit, David B.

Publication type:

Article

Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1520881

By:

Rassouli, Fatemeh B.;
Matin, Maryam M.;
Hadizadeh, Farzin;
Nejabat, Masoud;
Allahverdizadeh, Hossein;
Jamali, Hamidreza;
Gharedaghi, Shahin;
Hassanzadeh, Halimeh

Publication type:

Article

Osteonecrosis of the jaw in patients with clear cell renal cell carcinoma treated with targeted agents: a case series and large-scale pharmacovigilance analysis.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1309148

By:

Wang, Shuyun;
Zhang, Rui;
Wang, Song;
Guo, Qian;
Yin, Donghong;
Song, Yan;
She, Xianhua;
Wang, Xuyan;
Duan, Jinju

Publication type:

Article

Sunitinib promotes apoptosis via p38 MAPK activation and STAT3 downregulation in oral keratinocytes.

Published in:

Oral Diseases, 2024, v. 30, n. 2, p. 639, doi. 10.1111/odi.14457

By:

Fukada, Shohei;
Ohta, Kouji;
Sakuma, Miyuki;
Akagi, Misaki;
Kato, Hiroki;
Naruse, Takako;
Nakagawa, Takayuki;
Shigeishi, Hideo;
Nishi, Hiromi;
Takechi, Masaaki;
Aikawa, Tomonao

Publication type:

Article

Effect of tyrosine kinase inhibitor sunitinib on tissue repair at tooth extraction sites.

Published in:

Oral Diseases, 2023, v. 29, n. 3, p. 1070, doi. 10.1111/odi.14065

By:

Ratzkowski, Bruna;
Koth, Valesca S.;
Azambuja, Alan A.;
Salum, Fernanda G.;
de Figueiredo, Maria A. Z.;
Cherubini, Karen

Publication type:

Article

Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report.

Published in:

2024

By:

Zrinšćak, Ognjen;
Kasumović, Armin;
Krolo, Iva;
Ivekovic, Renata;
Malenica Ravlić, Maja;
Tomašković, Igor;
Vatavuk, Zoran

Publication type:

Case Study

Endobronchial Metastasis of Renal Cancer Presented as Atelectasis.

Published in:

Case Reports in Oncology, 2023, v. 16, n. 1, p. 1048, doi. 10.1159/000533893

By:

You, Jae Hyung;
Jeong, Young Beom

Publication type:

Article

Sunitinib-Induced Adrenal Crisis in a Patient with Pre-Existing Immunotherapy-Related Hypopituitarism.

Published in:

2022

By:

Javaid, Anadil;
Mathai, Jared;
Song, David;
Brown, Stephen

Publication type:

Case Study

Emerging Data on the Safety and Efficacy of Ripretinib for the Treatment of Gastrointestinal Stromal Tumors.

Published in:

Clinical & Experimental Gastroenterology, 2023, v. 16, p. 11, doi. 10.2147/CEG.S351839

By:

Thirasastr, Prapassorn;
Somaiah, Neeta

Publication type:

Article

A significant response to sunitinib in a patient with anaplastic thyroid carcinoma.

Published in:

Journal of Research in Medical Sciences, 2013, v. 18, n. 7, p. 623

By:

Grande, Enrique;
Capdevila, Jaume;
Diez, Juan José;
Longo, Federico;
Carrato, Alfredo

Publication type:

Article

A Score to Predict the Clinical Usefulness of Therapeutic Drug Monitoring: Application to Oral Molecular Targeted Therapies in Cancer.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 678, doi. 10.1002/cpt.3193

By:

Géraud, Arthur;
Combarel, David;
Funck‐Brentano, Christian;
Beaulieu, Quentin;
Zahr, Noël;
Broutin, Sophie;
Spano, Jean‐Philippe;
Massard, Christophe;
Besse, Benjamin;
Gougis, Paul

Publication type:

Article

Bevacizumab and sunitinib mediate osteogenic and pro-inflammatory molecular changes in primary human alveolar osteoblasts in vitro.

Published in:

Odontology, 2022, v. 110, n. 4, p. 634, doi. 10.1007/s10266-022-00691-y

By:

Hofmann, Elena;
Eggers, Benedikt;
Heim, Nils;
Kramer, Franz-Josef;
Nokhbehsaim, Marjan;
Götz, Werner

Publication type:

Article

Physiologically-based pharmacokinetic models versus allometric scaling for prediction of tyrosine-kinase inhibitor exposure from adults to children.

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 2, p. 297, doi. 10.1007/s00280-024-04678-0

By:

Centanni, Maddalena;
Zaher, Omar;
Elhad, David;
Karlsson, Mats O.;
Friberg, Lena E.

Publication type:

Article

Are novel oral oncolytics underdosed in obese patients?

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 2, p. 129, doi. 10.1007/s00280-023-04601-z

By:

Lin, Lishi;
van der Meer, Ellen K. O.;
Steeghs, Neeltje;
Beijnen, Jos H.;
Huitema, Alwin D. R.

Publication type:

Article

Cabozantinib exposure–response analysis for the phase 3 CheckMate 9ER trial of nivolumab plus cabozantinib versus sunitinib in first-line advanced renal cell carcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 2, p. 179, doi. 10.1007/s00280-022-04500-9

By:

Tran, Benjamin Duy;
Li, Jing;
Ly, Neang;
Faggioni, Raffaella;
Roskos, Lorin

Publication type:

Article

Feasibility of therapeutic drug monitoring of sunitinib and its implications on response and toxicity in patients with metastatic renal cell cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2022, v. 89, n. 6, p. 751, doi. 10.1007/s00280-022-04432-4

By:

Gandhi, Khushboo A.;
Joshi, Amit;
Mehta, Parsshava;
Gurjar, Murari;
Rane, Pallavi;
Sharma, Jyoti;
Patil, Anand;
Nookala, Manjunath;
Noronha, Vanita;
Prabhash, Kumar;
Gota, Vikram

Publication type:

Article

Adaptive dosing of sunitinib in a metastatic renal cell carcinoma patient: when in silico modeling helps to go quicker to the point.

Published in:

2022

By:

Ferrer, Florent;
Chauvin, Jonathan;
Deville, Jean-Laurent;
Ciccolini, Joseph

Publication type:

journal article

Hypertension toxicity of VEGFR-TKIs in cancer treatment: incidence, mechanisms, and management strategies.

Published in:

2025

By:

Du, Yan-Xi;
Li, Xu;
Ji, Si-Wen;
Niu, Na

Publication type:

Literature Review

Sunitinib-induced localized depigmentation over melasma in an elderly woman.

Published in:

Pigment International, 2022, v. 9, n. 2, p. 139, doi. 10.4103/pigmentinternational.pigmentinternational_11_22

By:

MURTHY, SAMBASIVIAH CHIDAMBARA;
SHANKAR, MEGHA;
NAGARAJ, NIVEDITHA;
SRIKANTAIAH, MEGHA

Publication type:

Article

核心蛋白聚糖、甲磺酸伊马替尼、苹果酸舒尼替尼对胃肠道间质瘤细胞恶性表型的影响.

Published in:

Journal of China Medical University, 2024, v. 53, n. 11, p. 961, doi. 10.12007/j.issn.0258‐4646.2024.11.001

By:

唐珊;
贾钧凯;
马鸿滢;
赵滢;
张天彪

Publication type:

Article

Prognostic significance of annexin A2 and tumor associated macrophages (TAMs) in metastatic renal cell carcinoma and their relation to Sunitinib resistance.

Published in:

Journal of Immunoassay & Immunochemistry, 2024, v. 45, n. 1, p. 1, doi. 10.1080/15321819.2023.2285501

By:

Heabah, Nehal Abd El-Ghaffar;
Darwish, Sara A.;
Ibrahim, Fatma MKh

Publication type:

Article

Sunitinib's Effect on Bilateral Optic Nerve Damage in Rats Following the Unilateral Clamping and Unclamping of the Common Carotid Artery.

Published in:

Biomedicines, 2025, v. 13, n. 3, p. 620, doi. 10.3390/biomedicines13030620

By:

Cicek, Ibrahim;
Esenulku, Cenap Mahmut;
Somuncu, Ahmet Mehmet;
Bulut, Seval;
Yucel, Nurinisa;
Bal Tastan, Tugba;
Coban, Taha Abdulkadir;
Suleyman, Halis

Publication type:

Article

Clinical Significance and Expression Pattern of RIP5 and VGLL4 in Clear Cell Renal Cell Carcinoma Patients Treated with Sunitinib.

Published in:

Biomedicines, 2024, v. 12, n. 1, p. 149, doi. 10.3390/biomedicines12010149

By:

Tomić, Tanja;
Tomić, Davor;
Vukoja, Martina;
Kraljević, Marija;
Ljevak, Ivona;
Glamočlija, Una;
Tomić, Vajdana;
Vukojević, Katarina;
Beljan Perak, Renata;
Šoljić, Violeta

Publication type:

Article

Catfish Egg Lectin Enhances the Cytotoxicity of Sunitinib on Gb3-Expressing Renal Cancer Cells.

Published in:

Biomedicines, 2023, v. 11, n. 8, p. 2317, doi. 10.3390/biomedicines11082317

By:

Ito, Jun;
Sugawara, Shigeki;
Tatsuta, Takeo;
Hosono, Masahiro;
Sato, Makoto

Publication type:

Article

Whole Exome Sequencing Identifies PHF14 Mutations in Neurocytoma and Predicts Responsivity to the PDGFR Inhibitor Sunitinib.

Published in:

Biomedicines, 2022, v. 10, n. 11, p. 2842, doi. 10.3390/biomedicines10112842

By:

Zhang, Dongyun;
Yong, William;
Movassaghi, Masoud;
Rodriguez, Fausto J.;
Yang, Issac;
McKeever, Paul;
Qian, Jiang;
Li, Jian Yi;
Mao, Qinwen;
Newell, Kathy L.;
Green, Richard M.;
Welsh, Cynthia T.;
Heaney, Anthony P.

Publication type:

Article

Immune Checkpoint Inhibitor Combination Therapy versus Sunitinib as First-Line Treatment for Favorable-IMDC-Risk Advanced Renal Cell Carcinoma Patients: A Meta-Analysis of Randomized Clinical Trials.

Published in:

Biomedicines, 2022, v. 10, n. 3, p. 577, doi. 10.3390/biomedicines10030577

By:

Manneh, Ray;
Lema, Mauricio;
Carril-Ajuria, Lucía;
Ibatá, Linda;
Martínez, Susan;
Castellano, Daniel;
de Velasco, Guillermo

Publication type:

Article

PDIA4 在肾癌细胞舒尼替尼耐药中的作用研究.

Published in:

Progress in Modern Biomedicine, 2024, v. 24, n. 13, p. 2408, doi. 10.13241/j.cnki.pmb.2024.13.002

By:

唐麒麟;
柯波亮;
何雏江;
徐子杰;
陈磊;
邵怡

Publication type:

Article

Pharmacovigilance imbalance analysis of VEGFR-TKI-related taste and smell disorders.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87678-1

By:

Fu, Zhong-hua;
Zhao, Chenglong;
Wang, Yaqin;
Zhang, Lei;
Wang, Lei

Publication type:

Article

Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 2, p. 102, doi. 10.3390/cells14020102

By:

Khodadust, Fatemeh;
Philippon, Eva M. L.;
Steinz, Maarten M.;
van Hamburg, Jan Piet;
van Meerloo, Johan;
van Beijnum, Judy R.;
Jansen, Gerrit;
Tas, Sander W.;
van der Laken, Conny J.

Publication type:

Article

Indole Antitumor Agents in Nanotechnology Formulations: An Overview.

Published in:

Pharmaceutics, 2023, v. 15, n. 7, p. 1815, doi. 10.3390/pharmaceutics15071815

By:

Russo, Eleonora;
Grondona, Carola;
Brullo, Chiara;
Spallarossa, Andrea;
Villa, Carla;
Tasso, Bruno

Publication type:

Article

Practical Recommendations for the Manipulation of Kinase Inhibitor Formulations to Age-Appropriate Dosage Forms.

Published in:

Pharmaceutics, 2022, v. 14, n. 12, p. 2834, doi. 10.3390/pharmaceutics14122834

By:

Bernsen, Emma C.;
Hogenes, Valery J.;
Nuijen, Bastiaan;
Hanff, Lidwien M.;
Huitema, Alwin D. R.;
Diekstra, Meta H. M.

Publication type:

Article

1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 1, p. 81, doi. 10.3390/ph17010081

By:

Elsawi, Ahmed E.;
Shahin, Mai I.;
Elbendary, Hager A.;
Al-Warhi, Tarfah;
Hassan, Fatma E.;
Eldehna, Wagdy M.

Publication type:

Article

Discovery of New Pyrrolo[2,3- d ]pyrimidine Derivatives as Potential Multi-Targeted Kinase Inhibitors and Apoptosis Inducers.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 9, p. 1324, doi. 10.3390/ph16091324

By:

Alotaibi, AbdulAziz A.;
Alanazi, Mohammed M.;
Rahman, A. F. M. Motiur

Publication type:

Article

Design, Synthesis, and Biological Evaluation of 2-Mercaptobenzoxazole Derivatives as Potential Multi-Kinase Inhibitors.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 1, p. 97, doi. 10.3390/ph16010097

By:

Alanazi, Mohammed M.;
Aldawas, Saleh;
Alsaif, Nawaf A.

Publication type:

Article