Works about SUBTILISINS

Results: 533

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 5, p. 413, doi. 10.1038/nsmb1235

By:

Cunningham, David;
Danley, Dennis E.;
Geoghegan, Kieran F.;
Griffor, Matthew C.;
Hawkins, Julie L.;
Subashi, Timothy A.;
Varghese, Alison H.;
Ammirati, Mark J.;
Culp, Jeffrey S.;
Hoth, Lise R.;
Mansour, Mahmoud N.;
McGrath, Katherine M.;
Seddon, Andrew P.;
Shenolikar, Shirish;
Stutzman-Engwall, Kim J.;
Warren, Laurie C.;
Donghui Xia;
Xiayang Qiu

Publication type:

Article

Subtilisin like proteins in the war between Grapevine and Plasmopara viticola isolates with contrasting aggressiveness.

Published in:

European Journal of Plant Pathology, 2021, v. 159, n. 2, p. 433, doi. 10.1007/s10658-020-02155-x

By:

Gouveia, Catarina;
Zukic, Selma;
Manthey, Thorsten;
Malhó, Rui;
Buchholz, Guenther;
Figueiredo, Andreia

Publication type:

Article

Oxidized low-density lipoprotein (oxLDL) affects load-free cell shortening of cardiomyocytes in a proprotein convertase subtilisin/kexin 9 (PCSK9)-dependent way.

Published in:

Basic Research in Cardiology, 2017, v. 112, n. 6, p. 1, doi. 10.1007/s00395-017-0650-1

By:

Schlüter, Klaus-Dieter;
Wolf, Annemarie;
Weber, Martin;
Schreckenberg, Rolf;
Schulz, Rainer

Publication type:

Article

Biochemical features of microbial keratinases and their production and applications.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 85, n. 6, p. 1735, doi. 10.1007/s00253-009-2398-5

By:

Brandelli, Adriano;
Daroit, Daniel J.;
Riffel, Alessandro

Publication type:

Article

Alkaliphilic Bacillus sp. strain KSM-LD1 contains a record number of subtilisin-like serine proteases genes.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 76, n. 2, p. 395, doi. 10.1007/s00253-007-1022-9

By:

Takimura, Yasushi;
Saito, Kazuhiro;
Okuda, Mitsuyoshi;
Kageyama, Yasushi;
Saeki, Katsuhisa;
Ozaki, Katsuya;
Ito, Susumu;
Kobayashi, Tohru

Publication type:

Article

Functional identification of the gene bace16 from nematophagous bacterium Bacillus nematocida.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 75, n. 1, p. 141, doi. 10.1007/s00253-006-0794-7

By:

Qiuhong Niu;
Xiaowei Huang;
Lin Zhang;
Lihui Lian;
Yunxia Li;
Juan Li;
Jinkui Yang;
Keqin Zhang

Publication type:

Article

A new approach for alteration of protease functions: pro-sequence engineering.

Published in:

Applied Microbiology & Biotechnology, 2003, v. 63, n. 1, p. 1, doi. 10.1007/s00253-003-1352-1

By:

Takagi, H.;
Takahashi, M.

Publication type:

Article

Efficient clustering of identity-by-descent between multiple individuals.

Published in:

Bioinformatics, 2014, v. 30, n. 7, p. 915, doi. 10.1093/bioinformatics/btt734

By:

Qian, Yu;
Browning, Brian L.;
Browning, Sharon R.

Publication type:

Article

枯草杆菌蛋白酶水解对大豆蛋白肽谱变化规律的影响.

Published in:

Food Research & Development, 2023, v. 44, n. 19, p. 49, doi. 10.12161/j.issn.1005-6521.2023.19.007

By:

焦艳玲;
陶晓露;
许伟洲;
于文娟;
路福平;
王洪彬

Publication type:

Article

The management of familial hypercholesterolaemia with statin-associated muscle symptoms.

Published in:

SA Pharmaceutical Journal Incorporating Pharmacy Management, 2018, v. 85, n. 3, p. 20

By:

Schellack, N.;
Schellack, G.;
Bronkhorst, E.;
van der Sandt, N.;
Schoeman, J.;
de Klerk, H.

Publication type:

Article

Circulating PCSK9 Level and Risk of Cardiovascular Events and Death in Hemodialysis Patients.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 244, doi. 10.3390/jcm9010244

By:

Hwang, Hyeon Seok;
Kim, Jin Sug;
Kim, Yang Gyun;
Lee, So-Young;
Ahn, Shin Young;
Lee, Hong Joo;
Lee, Dong-Young;
Lee, Sang Ho;
Moon, Ju Young;
Jeong, Kyung Hwan

Publication type:

Article

Genome-Wide Identification, Phylogeny and Expression Analysis of Subtilisin (SBT) Gene Family under Wheat Biotic and Abiotic Stress.

Published in:

Plants (2223-7747), 2023, v. 12, n. 17, p. 3065, doi. 10.3390/plants12173065

By:

Zhao, Xiaotong;
Goher, Farhan;
Chen, Lei;
Song, Jiancheng;
Zhao, Jiqiang

Publication type:

Article

Identification and characterization of a surface-associated, subtilisin-like serine protease in Trichomonas vaginalis.

Published in:

Parasitology, 2010, v. 137, n. 11, p. 1621, doi. 10.1017/S003118201000051X

By:

Hernández-Romano, Pablo;
Hernández, Roberto;
Arroyo, Rossana;
Alderete, John F.;
LóPez-Villaseñor, Imelda

Publication type:

Article

The mechanical properties of chick (Gallus domesticus) sensory hair bundles: relative contributions of structures sensitive to calcium chelation and subtilisin treatment.

Published in:

Journal of Physiology, 2004, v. 559, n. 1, p. 287, doi. 10.1113/jphysiol.2004.065565

By:

Bashtanov, Mikhail E.;
Goodyear, Richard J.;
Richardson, Guy P.;
Russell, Ian J.

Publication type:

Article

Ubiquitin ligase RNF5 serves an important role in the development of human glioma.

Published in:

Oncology Letters, 2019, v. 18, n. 5, p. 4659, doi. 10.3892/ol.2019.10801

By:

Gao, Yong;
Xuan, Chengmin;
Jin, Mingwei;
An, Qi;
Zhuo, Baobiao;
Chen, Xincheng;
Wang, Lei;
Wang, Yuan;
Sun, Qingzeng;
Shi, Yingchun

Publication type:

Article

Proprotein convertase subtilisin/kexin type 6 activates the extracellular signal-regulated kinase 1/2 and Wnt family member 3A pathways and promotes in vitro proliferation, migration and invasion of breast cancer MDA-MB-231 cells.

Published in:

Oncology Letters, 2018, v. 16, n. 1, p. 145, doi. 10.3892/ol.2018.8654

By:

Wang, Ping;
Wang, Feifei;
Wang, Lin;
Pan, Jihong

Publication type:

Article

Interleukin-8 (IL-8) as a Potential Mediator of an Association between Trimethylamine N-Oxide (TMAO) and Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) among African Americans at Risk of Cardiovascular Disease.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 12, p. 1196, doi. 10.3390/metabo12121196

By:

Baginski, Alyssa M.;
Farmer, Nicole;
Baumer, Yvonne;
Wallen, Gwenyth R.;
Powell-Wiley, Tiffany M.

Publication type:

Article

Lipid Parameters and Proprotein Convertase Subtilisin/Kexin Type 9 in Healthy Lebanese Adults.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 8, p. 690, doi. 10.3390/metabo12080690

By:

Gannagé-Yared, Marie-Hélène;
Naous, Elie;
Al Achkar, Anis;
Issa, Wadih;
Sleilaty, Ghassan;
Barakett-Hamade, Vanda;
Abifadel, Marianne

Publication type:

Article

The Association of Proprotein Convertase Subtilisin/Kexin Type 9 to Plasma Low-Density Lipoproteins: An Evaluation of Different Methods.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 12, p. 861, doi. 10.3390/metabo11120861

By:

Canclini, Laura;
Malvandi, Amir Mohammad;
Uboldi, Patrizia;
Jabnati, Najoua;
Grigore, Liliana;
Zambon, Alberto;
Baragetti, Andrea;
Catapano, Alberico Luigi

Publication type:

Article

Proteinuria-Lowering Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Chronic Kidney Disease Patients: A Real-World Multicentric Study.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 11, p. 760, doi. 10.3390/metabo11110760

By:

Muñoz Ramos, Patricia;
Gil Giraldo, Yohana;
Álvarez-Chiva, Vicente;
Arroyo, David;
Sango Merino, Cristina;
Moncho Francés, Francesc;
Ocaña, Javier;
Reque, Javier;
Sánchez-Álvarez, Emilio;
Górriz, José Luis;
Quiroga, Borja

Publication type:

Article

Significance of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) for the Monitoring of Treatment Response to Cyclosporine in Patients with Psoriasis.

Published in:

Life (2075-1729), 2023, v. 13, n. 9, p. 1873, doi. 10.3390/life13091873

By:

Frątczak, Aleksandra;
Miziołek, Bartosz;
Łupicka-Słowik, Agnieszka;
Sieńczyk, Marcin;
Polak, Karina;
Bergler-Czop, Beata

Publication type:

Article

Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.1017978

By:

Falkenberg, Fabian;
Bott, Michael;
Bongaerts, Johannes;
Siegert, Petra

Publication type:

Article

Identification of Key Residues Essential for the Activation of Plant Immunity by Subtilisin From Bacillus velezensis LJ02.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.869596

By:

Jianan Hu;
Ruokui Chang;
Yujin Yuan;
Zhuoran Li;
Yuanhong Wang

Publication type:

Article

Genomic Polymorphism Identifies a Subtilisin-Like Protease near the Rhg4 Locus in Soybean.

Published in:

Crop Science, 2004, v. 44, n. 1, p. 265, doi. 10.2135/cropsci2004.2650

By:

Nelsen, Naoma S.;
Zhigang Li;
Warner, April L.;
Matthews, Benjamin F.;
Knap, Halina T.

Publication type:

Article

The subtilisin-like protease SBT3 contributes to insect resistance in tomato.

Published in:

Journal of Experimental Botany, 2016, v. 67, n. 14, p. 4325, doi. 10.1093/jxb/erw220

By:

Meyer, Michael;
Huttenlocher, Franziska;
Cedzich, Anna;
Procopio, Susanne;
Stroeder, Jasper;
Pau-Roblot, Corinne;
Lequart-Pillon, Michelle;
Pelloux, Jérôme;
Stintzi, Annick;
Schaller, Andreas

Publication type:

Article

SASP, a Senescence-Associated Subtilisin Protease, is involved in reproductive development and determination of silique number in Arabidopsis.

Published in:

Journal of Experimental Botany, 2015, v. 66, n. 1, p. 161, doi. 10.1093/jxb/eru409

By:

Martinez, Dana E.;
Borniego, Maria L.;
Battchikova, Natalia;
Aro, Eva-Mari;
Tyystjärvi, Esa;
Guiamét, Juan J.

Publication type:

Article

Role of Proprotein Convertase Subtilisin/Kexin Type 9 in the Pathogenesis of Graves' Orbitopathy in Orbital Fibroblasts.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.607144

By:

Lee, Ga Eun;
Kim, Jinjoo;
Lee, Jihei Sara;
Ko, JaeSang;
Lee, Eun Jig;
Yoon, Jin Sook

Publication type:

Article

Safety and Tolerability of PCSK9 Inhibitors: Current Insights.

Published in:

Clinical Pharmacology, 2020, v. 12, p. 191, doi. 10.2147/CPAA.S288831

By:

Kosmas, Constantine E;
Skavdis, Andreas;
Sourlas, Andreas;
Papakonstantinou, Evangelia J;
Genao, Edilberto Peña;
Uceta, Rogers Echavarria;
Guzman, Eliscer

Publication type:

Article

A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects.

Published in:

Clinical Pharmacology, 2019, v. 11, p. 145, doi. 10.2147/CPAA.S208033

By:

Liu, Chao;
Lu, Hong;
Yuan, Fei;
Chen, Wei-Li;
Xu, Hong-Rong;
Li, Hui;
Hsu, Cheng-Pang;
Egbuna, Ogo;
Wu, Jihua;
Dias, Clapton;
Abosaleem, Bassam;
Rana, Jitesh;
Monsalvo, Maria Laura;
Li, Xue-Ning;
Yu, Zhigang

Publication type:

Article

Interplay between microRNAs, Serum Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), and Lipid Parameters in Patients with Very High Lipoprotein(a) Treated with PCSK9 Inhibitors.

Published in:

Genes, 2023, v. 14, n. 3, p. 632, doi. 10.3390/genes14030632

By:

Levstek, Tina;
Karun, Tina;
Rehberger Likozar, Andreja;
Šebeštjen, Miran;
Trebušak Podkrajšek, Katarina

Publication type:

Article

PCSK9 and triglyceride-rich lipoprotein metabolism.

Published in:

Journal of Biomedical Research, 2015, v. 29, n. 6, p. 429, doi. 10.7555/JBR.29.20150052

By:

Druce, Irena;
Abujrad, Hussein;
Ooi, Teik Chye

Publication type:

Article

Esterification of Secondary Alcohols and Multi-hydroxyl Compounds by Candida antarctica Lipase B and Subtilisin.

Published in:

Biotechnology & Bioprocess Engineering, 2019, v. 24, n. 1, p. 41, doi. 10.1007/s12257-018-0379-1

By:

Cha, Hee-Jeong;
Park, Jin-Byung;
Park, Seongsoon

Publication type:

Article

PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0210808

By:

Mitchell, Kellie A.;
Moore, Justin Xavier;
Rosenson, Robert S.;
Irvin, Ryan;
Guirgis, Faheem W.;
Shapiro, Nathan;
Safford, Monika;
Wang, Henry E.

Publication type:

Article

Treatment of hypercholesterolaemia with PCSK9 inhibitors in patients after cardiac transplantation.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210373

By:

Kühl, Michael;
Binner, Christian;
Jozwiak, Joanna;
Fischer, Julia;
Hahn, Jochen;
Addas, Alaeldin;
Dinov, Boris;
Garbade, Jens;
Hindricks, Gerhard;
Borger, Michael

Publication type:

Article

The cysteine protease dipeptidyl aminopeptidase 3 does not contribute to egress of Plasmodium falciparum from host red blood cells.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0193538

By:

Ghosh, Sreejoyee;
Chisholm, Scott A.;
Dans, Madeline;
Lakkavaram, Asha;
Kennedy, Kit;
Ralph, Stuart A.;
Counihan, Natalie A.;
de Koning-Ward, Tania F.

Publication type:

Article

Surface‐associated residues in subtilisins contribute to poly‐L‐lactic acid depolymerization via enzyme adsorption.

Published in:

Microbial Biotechnology, 2024, v. 17, n. 6, p. 1, doi. 10.1111/1751-7915.14473

By:

Cannon, Jordan A.;
Zhou, Yue;
Qualey, Luke T.;
Reynolds, Todd B.

Publication type:

Article

Efectividad y seguridad del uso de inhibidores de PCSK9 en el tratamiento de la dislipidemia en el paciente con insuficiencia renal.

Published in:

Nefrologia, 2020, v. 40, n. 5, p. 499, doi. 10.1016/j.nefro.2020.04.020

By:

Quiroga, Borja;
Muñoz Ramos, Patricia;
Álvarez Chiva, Vicente

Publication type:

Article

Virulence testing and extracellular subtilisin-like (Pr1) and trypsin-like (Pr2) activity during propagule production of Paecilomyces fumosoroseus isolates from whiteflies (Homoptera: Aleyrodidae).

Published in:

IBEROAMERICANA. América Latina - España - Portugal, 2007, n. 25, p. 62

By:

Castellanos-Moguel, Judith;
González-Barajas, Margarita;
Mier, Teresa;
Reyes-Montes, María del Rocío;
Aranda, Eduardo;
Toriello, Conchita

Publication type:

Article

Cloning, expression and decoding of the cold adaptation of a new widely represented thermolabile subtilisin-like protease.

Published in:

Journal of Applied Microbiology, 2013, v. 114, n. 2, p. 352, doi. 10.1111/jam.12033

By:

Acevedo, J.P.;
Rodriguez, V.;
Saavedra, M.;
Muñoz, M.;
Salazar, O.;
Asenjo, J.A.;
Andrews, B.A.

Publication type:

Article

Influence of subtilisin on the adhesion of a marine bacterium which produces mainly proteins as extracellular polymers.

Published in:

Journal of Applied Microbiology, 2008, v. 105, n. 3, p. 791, doi. 10.1111/j.1365-2672.2008.03837.x

By:

Leroy, C.;
Delbarre, C.;
Ghillebaert, F.;
Compere, C.;
Combes, D.

Publication type:

Article

PCSK6-mediated corin activation is essential for normal blood pressure.

Published in:

Nature Medicine, 2015, v. 21, n. 9, p. 1048, doi. 10.1038/nm.3920

By:

Chen, Shenghan;
Cao, Pengxiu;
Dong, Ningzheng;
Peng, Jianhao;
Zhang, Chunyi;
Wang, Hao;
Zhou, Tiantian;
Yang, Junhua;
Zhang, Yue;
Martelli, Elizabeth E;
Naga Prasad, Sathyamangla V;
Miller, Rachel E;
Malfait, Anne-Marie;
Zhou, Yiqing;
Wu, Qingyu

Publication type:

Article

Cholesterol, racial variation and targeted medicines.

Published in:

Nature Medicine, 2005, v. 11, n. 2, p. 122, doi. 10.1038/nm0205-122

By:

Topol, Eric J.

Publication type:

Article

Subtilisin NAT, a subtilisin-like serine protease present in fermented soybean "natto" extract, inhibits Streptococcus mutans biofilm formation.

Published in:: Food Science & Technology Research, 2021, v. 27, n. 3, p. 7, doi. 10.3136/fstr.27.537
Publication type:: Article

Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0508-5

By:

Landowski, Christopher P.;
Mustalahti, Eero;
Wahl, Ramon;
Croute, Laurence;
Sivasiddarthan, Dhinakaran;
Westerholm-Parvinen, Ann;
Sommer, Benjamin;
Ostermeier, Christian;
Helk, Bernhard;
Saarinen, Juhani;
Saloheimo, Markku

Publication type:

Article

Subtilisin QK-2: secretory expression in Lactococcus lactis and surface display onto gram-positive enhancer matrix (GEM) particles.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0478-7

By:

Ruifeng Mao;
Kangping Zhou;
Zhenwei Han;
Yefu Wang

Publication type:

Article

Cloning and enhancing production of a detergent- and organic-solvent-resistant nattokinase from Bacillus subtilis VTCC-DVN-12-01 by using an eight-protease-gene-deficient Bacillus subtilis WB800.

Published in:

Microbial Cell Factories, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2859-12-79

By:

Thao Thi Nguyen;
Thi Dinh Quyen;
Hoang Thanh Le

Publication type:

Article

PAC1 Agonist Maxadilan Reduces Atherosclerotic Lesions in Hypercholesterolemic ApoE-Deficient Mice.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13245, doi. 10.3390/ijms252413245

By:

Mey, Lilli;
Bonaterra, Gabriel A.;
Hoffmann, Joy;
Schwarzbach, Hans;
Schwarz, Anja;
Eiden, Lee E.;
Weihe, Eberhard;
Kinscherf, Ralf

Publication type:

Article

The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates.

Published in:: PLoS Pathogens, 2010, v. 6, n. 11, p. 1, doi. 10.1371/journal.ppat.1001210
Publication type:: Article

Sex differences in LDL‐C reduction response to evolocumab: A propensity score matching analysis.

Published in:

Pharmacotherapy, 2024, v. 44, n. 11, p. 861, doi. 10.1002/phar.4619

By:

He, Ye‐Qian;
Wei, Yu‐Qing;
Huang, Guang‐Ming;
Liu, Guo‐Ping;
Lin, Zhong‐Qiu;
Liu, Tao‐Tao;
Jiang, Xia;
Lu, Jie‐Jiu

Publication type:

Article

Real‐world effectiveness of monoclonal antibody inhibitors of PCSK9 in patients with heterozygous familial hypercholesterolemia: A retrospective cohort study.

Published in:

Pharmacotherapy, 2024, v. 44, n. 9, p. 730, doi. 10.1002/phar.4609

By:

Siemens, Rebecca;
Pryjma, Mark;
Buchkowsky, Susan;
Barry, Arden R.

Publication type:

Article