Works matching DE "STAT proteins"

Results: 2625

Biaryl Phosphates and Phosphonates as Selective Inhibitors of the Transcription Factor STAT4.

Published in:

Angewandte Chemie, 2025, v. 137, n. 21, p. 1, doi. 10.1002/ange.202504420

By:

Brovchenko, Nadiya;
Berg, Angela;
Schubert, Sabine;
Gräb, Julian;
Münzel, Theresa;
Protzel, Christoph;
Natarajan, Kalaiselvi;
Berg, Thorsten

Publication type:

Article

Downregulation of STAT3 transcription factor reverses synaptotoxic phenotype of reactive astrocytes associated with prion diseases.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02028-6

By:

Kushwaha, Rajesh;
Molesworth, Kara;
Makarava, Natallia;
Baskakov, Ilia V.

Publication type:

Article

Association of STAT6 gene polymorphism with atopic asthma among Yemeni children in Sana'a city, Yemen.

Published in:

BMC Pediatrics, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12887-025-05710-9

By:

Abdulwahab Masood, Haitham;
Mohammed Othman, Arwa;
Nasr Addin Al-Sonboli, Najla;
Abdulnoor Ghlab, Faiza;
Mohammed Al-Haidary, Naif;
Al-Shaibani, Muhanna M.

Publication type:

Article

Relaxin 2 Suppresses Tumor Growth in Esophageal Squamous Cell Carcinoma EC9706 Cells Through Modulation of the STAT Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 5, p. 1, doi. 10.1002/jbt.70288

By:

Wang, Juzheng;
Wang, Lv;
Wang, Qingshi;
Lu, Qiang

Publication type:

Article

Research on the functions and potential mechanisms of STAT3 in chronic myelogenous leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02492-5

By:

Feng, Xiaoyun;
Qin, Yufeng;
Feng, Yulong;
Zhuo, Yingquan

Publication type:

Article

Bavachin suppresses proliferation of laryngopharyngeal cancer by regulating the STAT3 and MAPK signaling pathways.

Published in:

Journal of Cancer, 2025, v. 16, n. 7, p. 2339, doi. 10.7150/jca.92956

By:

Xiaonan Yang;
Zhimin Ding;
Hongting Hua;
Ruijia Gan;
Dongdong Meng;
Yan Zang;
Han Xiao;
Dong Wang;
Wanjin Jiang;
Dongyu Si;
Xiang Wei;
Mei Zhang;
Huabing Zhang;
Chaobing Gao

Publication type:

Article

Selective inhibition of canonical STAT3 signaling suppresses K-ras mutant lung tumorigenesis and reinvigorates anti-tumor immunity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1575181

By:

Clowers, Michael J.;
Rahal, Zahraa;
Cho, Sung-Nam;
Krishna, Avantika;
Yuan, Bo;
Hamana Zorrilla, Leticia G.;
Eckols, T. Kris;
Kasembeli, Moses M.;
Liu, Samuel;
Peng, Stephen;
Ramos-Castaneda, Marco;
Thompson, Annamarie L.;
Rodriguez Reyna, Carlos Ignacio;
Larsen, Katherine E.;
Grimaldo, Maria T.;
Deng, Shanshan;
Karimi, Nastaran;
Chou, Cody;
Velasco, Walter V.;
Zarghooni, Melody

Publication type:

Article

Clinical features and outcomes in large granular lymphocyte leukemia − associated pure red cell aplasia with STAT3 mutation.

Published in:

Annals of Hematology, 2025, v. 104, n. 4, p. 2351, doi. 10.1007/s00277-025-06371-5

By:

Liu, Xiaoqing;
Chai, Xingxing;
Yu, Qingling;
Wang, Wei;
Long, Qiqiang;
Gong, Yuemin;
Zhang, Yawen;
Qiao, Chun;
Hao, Jianping;
He, Guangsheng

Publication type:

Article

The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002200

By:

Beiting, Daniel P.;
Hidano, Shinya;
Baggs, Julie E.;
Geskes, Jeanne M.;
Fang, Qun;
Wherry, E. John;
Hunter, Christopher A.;
Roos, David S.;
Cherry, Sara

Publication type:

Article

Tuning up STAT1.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002201

By:

Sedwick, Caitlin

Publication type:

Article

Development of Lysine Crotonyl‐Mimic Probe to Covalently Identify H3K27Cr Interacting Proteins.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 62, p. 1, doi. 10.1002/chem.202301624

By:

Guo, Xiaochun;
Wang, Yuena;
An, Yuhao;
Liu, Zhihong;
Liu, Jianbo;
Chen, Jiaxin;
Zhan, Mei‐miao;
Liang, Mingcha;
Hou, Zhanfeng;
Wan, Chuan;
Yin, Feng;
Wang, Rui;
Li, Zigang

Publication type:

Article

Noninvasive imaging of hepatocyte IL-6/STAT3 signaling pathway for evaluating inflammation responses induced by end-stage stored whole blood transfusion.

Published in:

Biotechnology Letters, 2019, v. 41, n. 6/7, p. 733, doi. 10.1007/s10529-019-02688-0

By:

Wang, Zhengjun;
Zhang, Yulong;
Zhou, Qianqian;
Ma, Ping;
Wang, Xiaohui;
Zhan, Linsheng

Publication type:

Article

High NF-κB and STAT3 activity in human urothelial carcinoma: a pilot study.

Published in:

World Journal of Urology, 2014, v. 32, n. 6, p. 1469, doi. 10.1007/s00345-014-1237-1

By:

Degoricija, Marina;
Šitum, Marijan;
Korać, Jelena;
Miljković, Ana;
Matić, Katarina;
Paradžik, Martina;
Marinović Terzić, Ivana;
Jerončić, Ana;
Tomić, Snježana;
Terzić, Janoš

Publication type:

Article

STAT5b gain-of-function disease in a child with mycobacterial osteomyelitis of the skull: rare presentation of an emerging disease entity.

Published in:

Child's Nervous System, 2023, v. 39, n. 8, p. 2071, doi. 10.1007/s00381-023-05997-y

By:

Kobets, Andrew J.;
Ahmad, Samuel;
Boyke, Andre;
Oriko, David;
Holland, Ryan;
Eisenberg, Rachel;
Alavi, Seyed Ahmad Naseri;
Abbott, Rick

Publication type:

Article

Coffee suppresses the differentiation of Th17 cells by inhibiting interleukin-6-induced phosphorylation of signal transducer and activator of transcription 3.

Published in:

European Food Research & Technology, 2016, v. 242, n. 7, p. 1141, doi. 10.1007/s00217-015-2618-4

By:

Okamoto, Yoshihiro;
Hara, Takazumi;
Itayama, Asuka;
Koike, Konomi

Publication type:

Article

GDF15 activates human fibroblast MRC5 cells via miR-338/STAT1 in silicosis.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01627-w

By:

Wu, Ge-Ting;
Tian, Qiu-Yan;
Xie, Bin;
Hu, Yong-Bin;
Deng, Zheng-Hao

Publication type:

Article

Correction to: TPTEP1 suppresses high glucose‑induced dysfunction in retinal vascular endothelial cells by interacting with STAT3 and targeting VEGFA.

Published in:

Acta Diabetologica, 2023, v. 60, n. 1, p. 143, doi. 10.1007/s00592-022-01979-9

By:

Sun, Xiaoping;
Lu, Yuebing;
Lei, Tao

Publication type:

Article

Association of STAT4 polymorphisms with hepatitis B virus infection and clearance in Chinese Han population.

Published in:

Amino Acids, 2016, v. 48, n. 11, p. 2589, doi. 10.1007/s00726-016-2283-3

By:

Jiang, Xianzhong;
Su, Kunkai;
Tao, Jingjing;
Fan, Rongli;
Xu, Yi;
Han, Haijun;
Li, Lanjuan;
Li, Ming

Publication type:

Article

Taurine chloramine modulates the expression of adipokines through inhibition of the STAT-3 signaling pathway in differentiated human adipocytes.

Published in:

Amino Acids, 2013, v. 45, n. 6, p. 1415, doi. 10.1007/s00726-013-1612-z

By:

Kim, Kyoung Soo;
Ji, Hye-In;
Chung, Hyunju;
Kim, Chakyeun;
Lee, Sang Hoon;
Lee, Yeon-Ah;
Yang, Hyung-In;
Yoo, Myung Chul;
Hong, Seung Jae

Publication type:

Article

Psychopharmacological Effects of Stimulation of the Functions of Neural Stem Cells by STAT3 Inhibitor under Conditions of Modeled Ethanol-Induced Encephalopathy.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 173, n. 5, p. 615, doi. 10.1007/s10517-022-05598-w

By:

Zyuz'kov, G. N.;
Zhdanov, V. V.;
Miroshnichenko, L. A.;
Polyakova, T. Yu.;
Stavrova, L. A.;
Simanina, E. V.;
Minakova, M. Yu.;
Agafonov, V. I.;
Churin, A. A.

Publication type:

Article

The Role of JAK and STAT3 in Regulation of Secretory Function of Neuroglial Cells of Different Types in Ethanol-Induced Neurodegenerationt.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 172, n. 6, p. 686, doi. 10.1007/s10517-022-05457-8

By:

Zyuz'kov, G. N.;
Zhdanov, V. V.;
Miroshnichenko, L. A.;
Polyakova, T. Yu.;
Simanina, E. V.;
Danilets, M. G.;
Minakova, M. Yu.;
Churin, A. A.;
Agafonov, V. I.

Publication type:

Article

Particular Role of JAK/STAT3 Signaling in Functional Control of Mesenchymal Progenitor Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 164, n. 3, p. 316, doi. 10.1007/s10517-018-3980-6

By:

Zyuz'kov, G.;
Udut, E.;
Miroshnichenko, L.;
Polyakova, T.;
Simanina, E.;
Stavrova, L.;
Chaikovskii, A.;
Agafonov, V.;
Borodulina, E.;
Timofeev, M.;
Zyuz'kova, Yu.;
Danilets, M.;
Zhdanov, V.;
Udut, V.

Publication type:

Article

Abrogation of STAT3 activation cascade by Ginkgolide C mitigates tumourigenesis in lung cancer preclinical model.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 12, p. 1630, doi. 10.1093/jpp/rgab114

By:

Yang, Min Hee;
Ha, In Jin;
Lee, Seok-Geun;
Um, Jae-Young;
Ahn, Kwang Seok

Publication type:

Article

Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 6, p. 808, doi. 10.1093/jpp/rgab022

By:

Demir, Yaprak Dilber Şimay;
Özdemir, Aysun;
Özdemir, Reyhan Gönbe;
Cevher, Setenay Cemre;
Çalışkan, Burcu;
Ark, Mustafa

Publication type:

Article

Persistence of STAT‐1 inhibition and induction of cytokine resistance in pancreatic β cells treated with St John's wort and its component hyperforin.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 1, p. 93, doi. 10.1111/jphp.12823

By:

Novelli, Michela;
Porozov, Svetlana;
Vantaggiato, Chiara;
Masiello, Pellegrino;
Beffy, Pascale;
Mascia, Fabrizio;
Gregorelli, Alex;
Menegazzi, Marta

Publication type:

Article

Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells.

Published in:

BMC Molecular & Cell Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12860-023-00482-5

By:

Zareifard, Amir;
Beaudry, Francis;
Ndiaye, Kalidou

Publication type:

Article

SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation.

Published in:

BMC Molecular & Cell Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12860-023-00481-6

By:

Wang, Kehuan;
Papadopoulos, Natalia;
Hamidi, Anahita;
Lennartsson, Johan;
Heldin, Carl-Henrik

Publication type:

Article

Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3.

Published in:

BMC Molecular & Cell Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12860-023-00471-8

By:

Xiao, Xiaoyue;
Zou, Shujuan;
Chen, Jianwei

Publication type:

Article

Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00422-9

By:

Behrendsen, Lena Sophie;
Menon, Priyanka Rajeev;
Khan, Muhammad Jawad;
Gregus, Anke;
Wirths, Oliver;
Meyer, Thomas;
Staab, Julia

Publication type:

Article

STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosis.

Published in:

NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00254-y

By:

Yanagimura, Naohiro;
Takeuchi, Shinji;
Fukuda, Koji;
Arai, Sachiko;
Tanimoto, Azusa;
Nishiyama, Akihiro;
Ogo, Naohisa;
Takahashi, Hiroyuki;
Asai, Akira;
Watanabe, Satoshi;
Kikuchi, Toshiaki;
Yano, Seiji

Publication type:

Article

Sensory processing: Itchy astrocytes.

Published in:

Nature Reviews Neuroscience, 2015, v. 16, n. 9, p. 508, doi. 10.1038/nrn4010

By:

Lewis, Sian

Publication type:

Article

Direct Comparison of Chol-siRNA Polyplexes and Chol-DsiRNA Polyplexes Targeting STAT3 in a Syngeneic Murine Model of TNBC.

Published in:

Non-Coding RNA, 2022, v. 8, n. 1, p. 8, doi. 10.3390/ncrna8010008

By:

Ye, Zhen;
Abdelmoaty, Mai Mohamed;
Curran, Stephen M.;
Dyavar, Shetty Ravi;
Kumar, Devendra;
Alnouti, Yazen;
Coulter, Don W.;
Podany, Anthony T.;
Singh, Rakesh K.;
Vetro, Joseph A.

Publication type:

Article

Tetrandrine-induced downregulation of lncRNA NEAT1 inhibits rheumatoid arthritis progression through the STAT3/miR-17-5p pathway.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 6, p. 886, doi. 10.1080/08923973.2022.2092748

By:

Duan, Bo;
Yu, Zhao;
Liu, Ruilin;
Li, Jigao;
Song, Zhe;
Zhou, Quan;
Chen, Lichuan

Publication type:

Article

STAT1 mediates the PI3K/AKT pathway through promoting microRNA-18a in nasal polyps.

Published in:

Immunopharmacology & Immunotoxicology, 2022, v. 44, n. 2, p. 194, doi. 10.1080/08923973.2021.2025388

By:

Jian, Baoshan;
Yin, Peng

Publication type:

Article

Chlorogenic acid and luteolin synergistically inhibit the proliferation of interleukin-1 β -induced fibroblast-like synoviocytes through regulating the activation of NF- κ B and JAK/STAT-signaling pathways.

Published in:

Immunopharmacology & Immunotoxicology, 2015, v. 37, n. 6, p. 499, doi. 10.3109/08923973.2015.1095763

By:

Lou, Lixia;
Liu, Yujun;
Zhou, Jingwei;
Wei, Yi;
Deng, Jiagang;
Dong, Bin;
Chai, Limin

Publication type:

Article

IL-17a promotes hepatocellular carcinoma by increasing FAP expression in hepatic stellate cells via activation of the STAT3 signaling pathway.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01995-4

By:

Sun, Dapeng;
Li, Wen;
Ding, Dongyang;
Tan, Kunjiang;
Ding, Wenbin;
Wang, Zongyan;
Fu, Siyuan;
Hou, Guojun;
Zhou, Wei-ping;
Gu, Fangming

Publication type:

Article

AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01700-x

By:

Gayatri, Meher Bolisetti;
Kancha, Rama Krishna;
Behera, Abhayananda;
Patchva, Dorababu;
Velugonda, Nagaraj;
Gundeti, Sadasivudu;
Reddy, Aramati Bindu Madhava

Publication type:

Article

Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01658-w

By:

Wang, Xianzhe;
Shi, Wei;
Wang, Xumei;
Lu, Jin-Jian;
He, Ping;
Zhang, Hongjie;
Chen, Xiuping

Publication type:

Article

Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01575-y

By:

Zhang, Meichao;
Meng, Yiling;
Ying, Yingxia;
Zhou, Pingting;
Zhang, Suning;
Fang, Yong;
Yao, Yuan;
Li, Dong

Publication type:

Article

Centella triterpenes cream as a potential drug for the treatment of hypertrophic scar through inhibiting the phosphorylation of STAT3: A network pharmacology analysis and in vitro experiments.

Published in:

Journal of Cosmetic Dermatology, 2023, v. 22, n. 12, p. 3511, doi. 10.1111/jocd.15883

By:

Tan, Ming;
Wu, Dan;
Zhou, Yanshijing;
Duan, Bo

Publication type:

Article

Lagerstroemia indica extract regulates human hair dermal papilla cell growth and degeneration via modulation of β‐catenin, Stat6, and TGF‐β signaling pathway.

Published in:

Journal of Cosmetic Dermatology, 2022, v. 21, n. 7, p. 2763, doi. 10.1111/jocd.15081

By:

Kim, Byung Hyun;
Kim, Myong Ki;
Choi, Bu Young

Publication type:

Article

Punicalagin Suppresses LPS-induced Inflammatory Responses in Murine Macrophages via JAK/STAT Signaling Pathway and Zymosan-induced Mice Paw Edema.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2021, v. 55, n. 2, p. 550, doi. 10.5530/ijper.55.2.93

By:

Huan Yan;
Gulimire, Abilaiti;
Junyu Zhu;
Huaping Liang;
Zhengyi Gu

Publication type:

Article

HISTORY OF INTERFERON TREATMENTS IN MULTIPLE SCLEROSIS - 60 YEARS OF PROGRESS.

Published in:

Farmacia, 2017, v. 65, n. 1, p. 14

By:

SÎRBU, CARMEN ADELLA;
DRĂGOI, CRISTINA MANUELA;
NICOLAE, ALINA CRENGUȚA;
PLEȘA, CRISTINA FLORENTINA

Publication type:

Article

INHIBITION OF NF-KB AND STAT3 BY QUERCETIN WITH SUPPRESSION OF ADHESION MOLECULE EXPRESSION IN VASCULAR ENDOTHELIAL CELLS.

Published in:

Farmacia, 2016, v. 64, n. 5, p. 668

By:

YOUNG-SUK CHO;
CHAN HYUNG KIM;
TAE-SUN HA;
HEE YUL AHN

Publication type:

Article

INVESTIGATION OF PLASMA SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 (STAT3) AND BCL‐2 ASSOCIATED X PROTEIN (BAX) LEVELS IN RATS FED HIGH FAT AND HIGH SUCROSE DIET.

Published in:

2017

By:

FİDAN, Kübra;
UNAT, Berivan;
YERLİKAYA, Fatma Hümeyra;
KAYA, Bülent;
İZCİ, Emir Kaan;
CÜCE, Gökhan;
CAN, Ümmü Gülsüm

Publication type:

Abstract

Primary solitary fibrous tumor of the thyroid gland: A review starting from a case report.

Published in:

2021

By:

Negură, Ion;
Ianole, Victor;
Dănilă, Radu;
Ungureanu, Maria-Christina;
Ciobanu Apostol, Delia Gabriela

Publication type:

Case Study

Chronic mucocutaneous candidiasis, pancytopenia, and systemic mycosis in a patient with STAT1 gene mutation ineffectively treated with ruxolitinib.

Published in:

Central European Journal of Immunology, 2022, v. 47, n. 1, p. 92, doi. 10.5114/ceji.2022.114884

By:

BAZAN-SOCHA, STANISŁAWA;
GRADZIKIEWICZ, ADA;
CELIŃSKA-LOWENHOFF, MAGDALENA;
MATYJA-BEDNARCZYK, ALEKSANDRA;
MACIOŁEK, ANNA;
BĄBOL-POKORA, KATARZYNA

Publication type:

Article

Membrane-proximal binding of STAT3 revealed by cancer-associated receptor variants.

Published in:

2016

By:

Ulaganathan, Vijay K.;
Ullrich, Axel

Publication type:

Opinion

STAT1-mediated translational control in tumor suppression and antitumor therapies.

Published in:

2016

By:

Wang, Shuo;
Koromilas, Antonis E.

Publication type:

Opinion

Unexpected oncosuppressive role for STAT3 in KRAS-induced lung tumorigenesis.

Published in:

2016

By:

Grabner, Beatrice;
Moll, Herwig P.;
Casanova, Emilio

Publication type:

Opinion