Works matching DE "SRC gene"

Results: 190

Dual Inhibition of SRC Family Kinases and Sorafenib Enhances Anti-Tumor Activity in Hepatocellular Carcinoma Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6506, doi. 10.3390/ijms26136506

By:

Cabral, Loraine Kay;
Disoma, Cyrollah;
Tarchi, Paola;
El-Khobar, Korri Elvanita;
Agustiningsih, Agustiningsih;
Dituri, Francesco;
Tiribelli, Claudio;
Sukowati, Caecilia

Publication type:

Article

Nano-selenium and the SRC family kinases pathway: Redefining gene expression dynamics in major depressive disorder based on a randomized controlled trial.

Published in:

Current Journal of Neurology, 2024, v. 23, n. 4, p. 240, doi. 10.18502/cjn.v23i4.18767

By:

Noormohammadi, Morvarid;
Etesam, Farnaz;
Amini, Ali;
Khosravian, Pegah;
Mohammadzadeh, Morteza;
Shidfar, Farzad

Publication type:

Article

Phosphorylation and externalization of galectin-4 is controlled by Src family kinases.

Published in:

Glycobiology, 2013, v. 23, n. 12, p. 1452, doi. 10.1093/glycob/cwt073

By:

Ideo, Hiroko;
Hoshi, Ikue;
Yamashita, Katsuko;
Sakamoto, Masaru

Publication type:

Article

Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology.

Published in:

Journal of Biological Rhythms, 2016, v. 31, n. 5, p. 443, doi. 10.1177/0748730416657921

By:

Fleet, Tiffany;
Stashi, Erin;
Zhu, Bokai;
Rajapakshe, Kimal;
Marcelo, Kathrina L.;
Kettner, Nicole M.;
Gorman, Blythe K.;
Coarfa, Cristian;
Fu, Loning;
O’Malley, Bert W.;
York, Brian

Publication type:

Article

CAR regulates epithelial cell junction stability through control of E-cadherin trafficking.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02889

By:

Morton, Penny E.;
Hicks, Alexander;
Nastos, Theodoros;
Santis, George;
Parsons, Maddy

Publication type:

Article

Dasatinib enhances antitumor activity of paclitaxel in ovarian cancer through Src signaling.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3249, doi. 10.3892/mmr.2015.3784

By:

JUAN XIAO;
MANMAN XU;
TENG HOU;
YONGWEN HUANG;
CHENLU YANG;
JUNDONG LI

Publication type:

Article

Suberoylanilide hydroxamic acid enhances the antitumor activity of oxaliplatin by reversing the oxaliplatin-induced Src activation in gastric cancer cells.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 5, p. 2729, doi. 10.3892/mmr.2014.2548

By:

CHENFEI ZHOU;
JUN JI;
MIN SHI;
LIU YANG;
YINGYAN YU;
BINGYA LIU;
ZHENGGANG ZHU;
JUN ZHANG

Publication type:

Article

Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro.

Published in:

Viruses (1999-4915), 2018, v. 10, n. 6, p. 283, doi. 10.3390/v10060283

By:

Shin, Jin Soo;
Jung, Eunhye;
Kim, Meehyein;
Baric, Ralph S.;
Go, Yun Young

Publication type:

Article

LKB1 suppresses melanoma metastasis: the answer is YES.

Published in:

Pigment Cell & Melanoma Research, 2012, v. 25, n. 6, p. 716, doi. 10.1111/pcmr.12009

By:

Kottakis, Filippos;
Gurumurthy, Sushma;
Bardeesy, Nabeel

Publication type:

Article

Gene selection using pyramid gravitational search algorithm.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0265351

By:

Tahmouresi, Amirhossein;
Rashedi, Esmat;
Yaghoobi, Mohammad Mehdi;
Rezaei, Masoud

Publication type:

Article

Pharmacological Inactivation of Src Family Kinases Inhibits LPS-Induced TNF-α Production in PBMC of Patients with Behçet’s Disease.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/5414369

By:

Irtegun, Sevgi;
Pektanc, Gulsum;
Akkurt, Zeynep M.;
Bozkurt, Mehtap;
Turkcu, Fatih M.;
Kalkanli-Tas, Sevgi

Publication type:

Article

GluA2 Trafficking Is Involved in Apoptosis of Retinal Ganglion Cells Induced by Activation of EphB/EphrinB Reverse Signaling in a Rat Chronic Ocular Hypertension Model.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 13, p. 5409, doi. 10.1523/JNEUROSCI.4376-14.2015

By:

Ling-Dan Dong;
Feng Gao;
Xiao-Han Wang;
Yanying Miao;
Shu-Yue Wang;
Yi Wu;
Fang Li;
Jihong Wu;
Xiang-Lin Cheng;
Xing-Huai Sun;
Xiong-Li Yang;
Zhongfeng Wang

Publication type:

Article

Neural Cell Adhesion Molecule 2 Promotes the Formation of Filopodia and Neurite Branching by Inducing Submembrane Increases in Ca2+ Levels.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 4, p. 1739, doi. 10.1523/JNEUROSCI.1714-14.2015

By:

Lifu Sheng;
Leshchyns'ka, Iryna;
Sytnyk, Vladimir

Publication type:

Article

Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.

Published in:

British Journal of Cancer, 2013, v. 109, n. 5, p. 1214, doi. 10.1038/bjc.2013.451

By:

van Oosterwijk, J G;
van Ruler, M A J H;
Briaire-de Bruijn, I H;
Herpers, B;
Gelderblom, H;
van de Water, B;
Bovée, J V M G

Publication type:

Article

Network Pharmacology Reveals Polyphyllin II as One Hit of Nano Chinese Medicine Monomers against Nasopharyngeal Carcinoma.

Published in:

Bioinorganic Chemistry & Applications, 2021, p. 1, doi. 10.1155/2021/9959634

By:

Yang, Meng-Zhe;
Zhang, Bei-Bei;
Huang, Jian-Chun;
Bai, Xian-Yu;
Liang, Zhen-Qiang;
Yi, Xiang;
Xu, Ning;
Huang, Yuan-Jiao;
Jiao, Ai-Jun

Publication type:

Article

Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/Akt-dependent NF-κB/p300 activation.

Published in:

Clinical Science, 2014, v. 127, n. 3, p. 171, doi. 10.1042/CS20130676

By:

Shin-Ei CHENG;
I-Ta LEE;
Chih-Chung LIN;
Li-Der HSIAO;
Chuen-Mao YANG

Publication type:

Article

Participation of Gab1 and Gab2 in IL-22-mediated keratinocyte proliferation, migration, and differentiation.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 369, n. 1/2, p. 255, doi. 10.1007/s11010-012-1389-5

By:

Zhu, Xiaofang;
Li, Zhongliang;
Pan, Wenyan;
Qin, Lu;
Zhu, Guoqiang;
Ke, Yuehai;
Wu, Jie;
Bo, Ping;
Meng, Songshu

Publication type:

Article

Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS.

Published in:

Histochemistry & Cell Biology, 2013, v. 140, n. 2, p. 213, doi. 10.1007/s00418-012-1073-6

By:

Terada, Nobuo;
Saitoh, Yurika;
Ohno, Nobuhiko;
Komada, Masayuki;
Yamauchi, Junji;
Ohno, Shinichi

Publication type:

Article

MicroRNA-206 inhibits the viability and migration of medulloblastoma cells by targeting LIM and SH3 protein 1.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 4, p. 3894, doi. 10.3892/etm.2017.5016

By:

XUEXIA PAN;
ZHIMIN WANG;
BIN WAN;
ZHENWEN ZHENG

Publication type:

Article

Signalling Pathways Passing Src in Pancreatic Endocrine Tumours: Relevance for Possible Combined Targeted Therapies.

Published in:

Neuroendocrinology, 2013, v. 97, n. 1, p. 67, doi. 10.1159/000336093

By:

Capurso, Gabriele;
Di Florio, alessia;
Sette, Claudio;
Delle Fave, Gianfranco

Publication type:

Article

AKT3 and PIK3R2 mutations in two patients with megalencephaly-related syndromes: MCAP and MPPH.

Published in:

Clinical Genetics, 2014, v. 85, n. 4, p. 396, doi. 10.1111/cge.12188

By:

Nakamura, K.;
Kato, M.;
Tohyama, J.;
Shiohama, T.;
Hayasaka, K.;
Nishiyama, K.;
Kodera, H.;
Nakashima, M.;
Tsurusaki, Y.;
Miyake, N.;
Matsumoto, N.;
Saitsu, H.

Publication type:

Article

Human TRPM8 and TRPA1 pain channels, including a gene variant with increased sensitivity to agonists (TRPA1 R797T), exhibit differential regulation by SRC-tyrosine kinase inhibitor.

Published in:

Bioscience Reports, 2014, v. 34, n. 4, p. 469, doi. 10.1042/BSR20140061

By:

MORGAN, Kevin;
SADOFSKY, Laura R.;
CROW, Christopher;
MORICE, Alyn H.

Publication type:

Article

Computational dissection of allosteric inhibition of the SH2 domain of Bcr-Abl kinase by the monobody inhibitor AS25.

Published in:

Journal of Molecular Modeling, 2017, v. 23, n. 6, p. 1, doi. 10.1007/s00894-017-3353-5

By:

Ji, Mingfei;
Zheng, Guodong;
Li, Xiaolong;
Zhang, Zhongqin;
Jv, Guanqun;
Wang, Xiaowei;
Wang, Jialin

Publication type:

Article

Mechanically Activated Fyn Utilizes mTORC2 to Regulate RhoA and Adipogenesis in Mesenchymal Stem Cells.

Published in:

Stem Cells, 2013, v. 31, n. 11, p. 2528, doi. 10.1002/stem.1476

By:

Thompson, William R.;
Guilluy, Christophe;
Xie, Zhihui;
Sen, Buer;
Brobst, Kaitlyn E.;
Yen, Sherwin S.;
Uzer, Gunes;
Styner, Maya;
Case, Natasha;
Burridge, Keith;
Rubin, Janet

Publication type:

Article

Downregulation of Src-kinase and glutamate-receptor phosphorylation after traumatic brain injury.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 10, p. 1642, doi. 10.1038/jcbfm.2013.121

By:

Park, Yujung;
Luo, Tianfei;
Zhang, Fan;
Liu, Chunli;
Bramlett, Helen M;
Dalton Dietrich, W;
Hu, Bingren

Publication type:

Article

HIF1α and HIF2α independently activate SRC to promote melanoma metastases.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2078, doi. 10.1172/JCI66715

By:

Hanna, Sara C.;
Krishnan, Bhavani;
Bailey, Sean T.;
Moschos, Stergios J.;
Pei-Fen Kuan;
Takeshi Shimamura;
Osborne, Lukas D.;
Siegel, Marni B.;
Duncan, Lyn M.;
O¿Brien III, E. Tim;
Superfine, Richard;
Miller, C. Ryan;
Simon, M. Celeste;
Kwok-Kin Wong;
Kim, William Y.

Publication type:

Article

The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2037, doi. 10.1172/JCI66397

By:

Tamiko R. Katsumoto;
Makoto Kudo;
Chun Chen;
Sundaram, Aparna;
Callahan, Elliott C.;
Jing W. Zhu;
Lin, Joseph;
Rosen, Connor E.;
Manz, Boryana N.;
Jae W. Lee;
Matthay, Michael A.;
Xiaozhu Huang;
Sheppard, Dean;
Weiss, Arthur

Publication type:

Article

A phase 2 study of KX2-391, an oral inhibitor of Src kinase and tubulin polymerization, in men with bone-metastatic castration-resistant prostate cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 4, p. 883, doi. 10.1007/s00280-013-2079-z

By:

Antonarakis, Emmanuel;
Heath, Elisabeth;
Posadas, Edwin;
Yu, Evan;
Harrison, Michael;
Bruce, Justine;
Cho, Steve;
Wilding, Gregory;
Fetterly, Gerald;
Hangauer, David;
Kwan, Min-Fun;
Dyster, Lyn;
Carducci, Michael

Publication type:

Article

The Src family kinase inhibitors PP2 and PP1 effectively block TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 2, p. 221, doi. 10.1007/s00280-012-1904-0

By:

Bartscht, Tobias;
Lehnert, Hendrik;
Gieseler, Frank;
Ungefroren, Hendrik

Publication type:

Article

Apoptosis Induced by Src-Family Tyrosine Kinase Inhibitors in Cultured Rat Cortical Cells.

Published in:

Neurotoxicity Research, 2012, v. 21, n. 3, p. 309, doi. 10.1007/s12640-011-9284-5

By:

Takadera, Tsuneo;
Fujibayashi, Mineki;
Koriyama, Yoshiki;
Kato, Satoru

Publication type:

Article

Chronic Ca2+ influx through voltage-dependent Ca2+ channels enhance delayed rectifier K+ currents via activating Src family tyrosine kinase in rat hippocampal neurons.

Published in:

Korean Journal of Physiology & Pharmacology, 2017, v. 21, n. 2, p. 259, doi. 10.4196/kjpp.2017.21.2.259

By:

Yoon-Sil Yang;
Sang-Chan Jeon;
Dong-Kwan Kim;
Su-Yong Eun;
Sung-Cherl Jung

Publication type:

Article

A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer.

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 4, p. 262, doi. 10.3390/jpm11040262

By:

Skopelitou, Diamanto;
Miao, Beiping;
Srivastava, Aayushi;
Kumar, Abhishek;
Kuświk, Magdalena;
Dymerska, Dagmara;
Paramasivam, Nagarajan;
Schlesner, Matthias;
Lubiński, Jan;
Hemminki, Kari;
Försti, Asta;
Bandapalli, Obul Reddy

Publication type:

Article

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases.

Published in:

Oncogene, 2015, v. 34, n. 44, p. 5593, doi. 10.1038/onc.2015.19

By:

Leroy, C;
Shen, Q;
Strande, V;
Meyer, R;
McLaughlin, M E;
Lezan, E;
Bentires-Alj, M;
Voshol, H;
Bonenfant, D;
Alex Gaither, L

Publication type:

Article

The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner.

Published in:

Oncogene, 2015, v. 34, n. 32, p. 4190, doi. 10.1038/onc.2014.347

By:

Shanzer, M;
Ricardo-Lax, I;
Keshet, R;
Reuven, N;
Shaul, Y

Publication type:

Article

Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk.

Published in:

Oncogene, 2015, v. 34, n. 32, p. 4260, doi. 10.1038/onc.2014.361

By:

Sriram, G;
Jankowski, W;
Kasikara, C;
Reichman, C;
Saleh, T;
Nguyen, K-Q;
Li, J;
Hornbeck, P;
Machida, K;
Liu, T;
Li, H;
Kalodimos, C G;
Birge, R B

Publication type:

Article

Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine.

Published in:

Oncogene, 2015, v. 34, n. 18, p. 2371, doi. 10.1038/onc.2014.163

By:

Kohlmaier, A;
Fassnacht, C;
Jin, Y;
Reuter, H;
Begum, J;
Dutta, D;
Edgar, B A

Publication type:

Article

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases.

Published in:

Oncogene, 2015, v. 34, n. 17, p. 2272, doi. 10.1038/onc.2014.170

By:

Sausgruber, N;
Coissieux, M-M;
Britschgi, A;
Wyckoff, J;
Aceto, N;
Leroy, C;
Stadler, M B;
Voshol, H;
Bonenfant, D;
Bentires-Alj, M

Publication type:

Article

A phase-1 study of dasatinib plus all-trans retinoic acid in acute myeloid leukemia.

Published in:

Leukemia & Lymphoma, 2018, v. 59, n. 11, p. 2595, doi. 10.1080/10428194.2018.1443330

By:

Redner, Robert L.;
Beumer, Jan H.;
Kropf, Patricia;
Agha, Mounzer;
Boyiadzis, Michael;
Dorritie, Kathleen;
Farah, Rafic;
Hou, Jing-Zhao;
Im, Annie;
Lim, Seah H.;
Raptis, Anastasios;
Sehgal, Alison;
Christner, Susan M.;
Normolle, Daniel;
Johnson, Daniel E.

Publication type:

Article

Src family kinases and their role in hematological malignancies.

Published in:

Leukemia & Lymphoma, 2015, v. 56, n. 3, p. 577, doi. 10.3109/10428194.2014.907897

By:

Ku, Matthew;
Wall, Meaghan;
MacKinnon, Ruth N.;
Walkley, Carl R.;
Purton, Louise E.;
Tam, Constantine;
Izon, David;
Campbell, Lynda;
Cheng, Heung-Chin;
Nandurkar, Harshal

Publication type:

Article

Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity.

Published in:

Genes, 2020, v. 11, n. 11, p. 1256, doi. 10.3390/genes11111256

By:

S., Udhaya Kumar;
Rajan, Bithia;
D., Thirumal Kumar;
V., Anu Preethi;
Abunada, Taghreed;
Younes, Salma;
Okashah, Sarah;
Ethiraj, Selvarajan;
C., George Priya Doss;
Zayed, Hatem

Publication type:

Article

Whole Genome Resequencing of Arkansas Progressor and Regressor Line Chickens to Identify SNPs Associated with Tumor Regression.

Published in:

Genes, 2018, v. 9, n. 10, p. 512, doi. 10.3390/genes9100512

By:

Khatri, Bhuwan;
Hayden, Ashley M.;
Anthony, Nicholas B.;
Kong, Byungwhi C.

Publication type:

Article

Src Inhibition Can Synergize with Gemcitabine and Reverse Resistance in Triple Negative Breast Cancer Cells via the AKT/c-Jun Pathway.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0169230

By:

Wu, Zhen-Hua;
Lin, Chen;
Liu, Ming-Ming;
Zhang, Jian;
Tao, Zhong-Hua;
Hu, Xi-Chun

Publication type:

Article

Src Family Kinases and p38 Mitogen-Activated Protein Kinases Regulate Pluripotent Cell Differentiation in Culture.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0163244

By:

Tan, Boon Siang Nicholas;
Kwek, Joly;
Wong, Chong Kum Edwin;
Saner, Nicholas J.;
Yap, Charlotte;
Felquer, Fernando;
Morris, Michael B.;
Gardner, David K.;
Rathjen, Peter D.;
Rathjen, Joy

Publication type:

Article

Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158839

By:

Huang, Yu-Han;
Yang, Hung-Yu;
Huang, Shiu-Wen;
Ou, George;
Hsu, Ya-Fen;
Hsu, Ming-Jen

Publication type:

Article

Microtubule and Actin Interplay Drive Intracellular c-Src Trafficking.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148996

By:

Arnette, Christopher;
Frye, Keyada;
Kaverina, Irina

Publication type:

Article

Novel Role of Src in Priming Pyk2 Phosphorylation.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149231

By:

Zhao, Ming;
Finlay, Darren;
Zharkikh, Irina;
Vuori, Kristiina

Publication type:

Article

Regulation of N-Formyl Peptide Receptor Signaling and Trafficking by Arrestin-Src Kinase Interaction.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147442

By:

Wagener, Brant M.;
Marjon, Nicole A.;
Prossnitz, Eric R.

Publication type:

Article

Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association with RBM10.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146593

By:

Yamada, Hazuki;
Tsutsumi, Koji;
Nakazawa, Yuki;
Shibagaki, Yoshio;
Hattori, Seisuke;
Ohta, Yasutaka

Publication type:

Article

SH2B1 is critical for the regulation of cardiac remodelling in response to pressure overload.

Published in:

Cardiovascular Research, 2015, v. 107, n. 2, p. 203, doi. 10.1093/cvr/cvv170

By:

Gang Wu;
Yu Liu;
He Huang;
Yanhong Tang;
Wanli Liu;
Yang Mei;
Nian Wan;
Xiaoxiong Liu;
Congxin Huang

Publication type:

Article

Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0076-5

By:

Sempou, Emily;
Biasini, Emiliano;
Pinzón-Olejua, Alejandro;
Harris, David A.;
Málaga-Trillo, Edward

Publication type:

Article