Works matching DE "SPIRAL ganglion"

Results: 237

Studies on the mechanism of ototoxic action of cisplatin and the antagonistic effect of polyphenolic compounds.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1586243

By:

Han, Shengyu;
Sun, Jinjun;
Li, Wenpeng;
Li, Jihong;
Yu, Haoming;
Wang, Shuai;
Chi, Yuhua

Publication type:

Article

Inhibition of TLR4 mitigates sensorineural hearing loss resulting from cochlear inflammation.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01219-0

By:

Lou, Jintao;
Wu, Fan;
Liu, Wei;
Hu, Rui;
He, Wuhui;
Feng, Yisi;
Huang, Yan;
Guo, Jia;
Deng, Jingman;
Zhao, Zhen;
Zhang, Zhigang;
Si, Yu

Publication type:

Article

Fasudil protects spiral ganglion neurons and hair cells against cisplatin-induced apoptosis by inhibiting reactive oxygen species accumulation and regulating the ROCK/PTEN/AKT signaling pathway.

Published in:

Toxicology Research, 2025, v. 14, n. 2, p. 1, doi. 10.1093/toxres/tfaf030

By:

Yin, Peng;
Jiang, Zhenhua;
Wang, Xue;
Gong, Shusheng;
Zhang, Cui;
Fan, Zhaomin

Publication type:

Article

The bidirectional brain–cochlea axis: a scaffold for neurologic disease-associated hearing loss.

Published in:

Brain Communications, 2024, v. 6, n. 6, p. 1, doi. 10.1093/braincomms/fcae403

By:

Stadio, Arianna Di;
Frohman, Elliot M;
Messineo, Daniela;
Brenner, Michael J;
Bernitsas, Evanthia

Publication type:

Article

Wnt Signaling Protects against Paclitaxel-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea In Vitro.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/7878906

By:

Wang, Xue;
Han, Yuechen;
Wang, Man;
Bo, Chuan;
Zhang, Zhenbiao;
Xu, Lei;
Liu, Wenwen;
Wang, Haibo

Publication type:

Article

Macrophage depletion attenuates degeneration of spiral ganglion neurons in kanamycin-induced unilateral hearing loss model.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43927-9

By:

Shimada, Mari Dias;
Noda, Masao;
Koshu, Ryota;
Takaso, Yuji;
Sugimoto, Hisashi;
Ito, Makoto;
Yoshizaki, Tomokazu;
Hori, Osamu

Publication type:

Article

Gata3 is required in late proneurosensory development for proper sensory cell formation and organization.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39707-0

By:

Blinkiewicz, Paige V.;
Long, Makayla R.;
Stoner, Zachary A.;
Ketchum, Elizabeth M.;
Sheltz-Kempf, Sydney N.;
Duncan, Jeremy S.

Publication type:

Article

Macrophage depletion attenuates degeneration of spiral ganglion neurons in kanamycin-induced unilateral hearing loss model.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43927-9

By:

Shimada, Mari Dias;
Noda, Masao;
Koshu, Ryota;
Takaso, Yuji;
Sugimoto, Hisashi;
Ito, Makoto;
Yoshizaki, Tomokazu;
Hori, Osamu

Publication type:

Article

Gata3 is required in late proneurosensory development for proper sensory cell formation and organization.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39707-0

By:

Blinkiewicz, Paige V.;
Long, Makayla R.;
Stoner, Zachary A.;
Ketchum, Elizabeth M.;
Sheltz-Kempf, Sydney N.;
Duncan, Jeremy S.

Publication type:

Article

Erratum: Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs.

Published in:: Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1384445
Publication type:: Article

Apical-basal distribution of different subtypes of spiral ganglion neurons in the cochlea and the changes during aging.

Published in:

PLoS ONE, 2023, v. 18, n. 10, p. 1, doi. 10.1371/journal.pone.0292676

By:

Wang, Meijian;
Lin, Shengyin;
Xie, Ruili

Publication type:

Article

In vitro impact of platinum nanoparticles on inner ear related cell culture models.

Published in:

PLoS ONE, 2023, v. 18, n. 4, p. 1, doi. 10.1371/journal.pone.0284794

By:

Berger, Elisabeth;
Brandes, Gudrun;
Reifenrath, Janin;
Lenarz, Thomas;
Durisin, Martin;
Wissel, Kirsten

Publication type:

Article

Spiral ganglion neuron degeneration in aminoglycoside-deafened rats involves innate and adaptive immune responses not requiring complement.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1389816

By:

Gansemer, Benjamin M.;
Rahman, Muhammad T.;
Zhenshen Zhang;
Green, Steven H.

Publication type:

Article

Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 01, doi. 10.3389/fnmol.2024.1351280

By:

Habakuk Hain, Paul Jakob;
Moser, Tobias

Publication type:

Article

Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 01, doi. 10.3389/fnmol.2023.1248941

By:

Karagulyan, Nare;
Moser, Tobias

Publication type:

Article

Salicylate Initiates Apoptosis in the Spiral Ganglion Neuron of Guinea Pig Cochlea by Activating Caspase-3.

Published in:

Neurochemical Research, 2011, v. 36, n. 6, p. 1108, doi. 10.1007/s11064-011-0455-9

By:

Feng, Hao;
Yin, Shi-Hua;
Tang, An-Zhou;
Tan, Song-Hua

Publication type:

Article

Contribution of macrophages to neural survival and intracochlear tissue remodeling responses following cochlear implantation.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02955-y

By:

Rahman, Muhammad Taifur;
Mostaert, Brian J.;
Hunger, Bryce;
Saha, Utsow;
Claussen, Alexander D.;
Razu, Ibrahim;
Nasrin, Farjana;
Khan, Nashwaan Ali;
Eckard, Peter;
Coleman, Sarah;
Oleson, Jacob;
Kirk, Jonathon R.;
Hirose, Keiko;
Hansen, Marlan R.

Publication type:

Article

Next-Generation Sequencing of Chinese Children with Congenital Hearing Loss Reveals Rare and Novel Variants in Known and Candidate Genes.

Published in:

Biomedicines, 2024, v. 12, n. 12, p. 2657, doi. 10.3390/biomedicines12122657

By:

Jin, Yuan;
Liu, Xiaozhou;
Zhang, Qiong;
Xiong, Ying;
Hu, Yao;
He, Haixia;
Chen, Wei;
Sun, Yu

Publication type:

Article

Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss.

Published in:

Biomedicines, 2023, v. 11, n. 12, p. 3347, doi. 10.3390/biomedicines11123347

By:

Lye, Joey;
Delaney, Derek S.;
Leith, Fiona K.;
Sardesai, Varda S.;
McLenachan, Samuel;
Chen, Fred K.;
Atlas, Marcus D.;
Wong, Elaine Y. M.

Publication type:

Article

Metabolomics Analysis Reveals Alterations in Cochlear Metabolic Profiling in Mice with Noise-Induced Hearing Loss.

Published in:

BioMed Research International, 2022, p. 1, doi. 10.1155/2022/9548316

By:

Miao, Long;
Zhang, Juan;
Yin, Lihong;
Pu, Yuepu

Publication type:

Article

Impedance spectroscopy of enlarged cochlear implant stimulation electrodes – FEM simulations considering the perilymph.

Published in:

Technisches Messen, 2023, v. 90, n. 12, p. 809, doi. 10.1515/teme-2023-0091

By:

Sehlmeyer, Merle;
Bhavsar, Mit B.;
Biebighaeuser, Julian;
Hitzemann, Moritz;
Maier, Hannes;
Lippmann, Martin;
Schaefer, Christoph;
Zimmermann, Stefan

Publication type:

Article

Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1125948

By:

Al Aameri, Raheem F. H.;
Alanisi, Entkhab M. A.;
Oluwatosin, Adu;
Al Sallami, Dheyaa;
Sheth, Sandeep;
Alberts, Ian;
Patel, Shree;
Rybak, Leonard P.;
Ramkumar, Vickram

Publication type:

Article

HIF-1α as a Target Molecule in the Use of Triazino-Indole Derivative on the Acoustic Trauma Model.

Published in:

Audiology Research, 2021, v. 11, n. 3, p. 365, doi. 10.3390/audiolres11030034

By:

Pastushenkov, Vladimir L.;
Buynov, Leonid G.;
Kuznetsov, Maksim S.;
Dvorianchikov, Vladimir V.;
Glaznikov, Lev A.;
Pastushenkov, Aleksandr L.

Publication type:

Article

Meta-Analysis--Correlation between Spiral Ganglion Cell Counts and Speech Perception with a Cochlear Implant.

Published in:

Audiology Research, 2021, v. 11, n. 2, p. 220, doi. 10.3390/audiolres11020020

By:

Yew-Song Cheng;
Svirsky, Mario A.

Publication type:

Article

Mitochondrial alterations in the cochlea of Cdk5rap1‐knockout mice with age‐related hearing loss.

Published in:

FEBS Open Bio, 2023, v. 13, n. 7, p. 1365, doi. 10.1002/2211-5463.13655

By:

Miwa, Toru;
Katsuno, Tatsuya;
Wei, Fan‐Yan;
Tomizawa, Kazuhito

Publication type:

Article

Sex differences in glutamate AMPA receptor subunits mRNA with fast gating kinetics in the mouse cochlea.

Published in:

Frontiers in Systems Neuroscience, 2023, v. 17, p. 1, doi. 10.3389/fnsys.2023.1100505

By:

Lozier, Nicholas R.;
Muscio, Steven;
Pal, Indra;
Hou-Ming Cai;
Rubio, María E.

Publication type:

Article

Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2020.

Published in:

Neural Plasticity, 2021, p. 1, doi. 10.1155/2021/9897461

By:

Chai, Renjie;
Li, Geng-lin;
Wang, Jian;
Zou, Jing;
Huang, Hai

Publication type:

Article

Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat.

Published in:

Neural Plasticity, 2020, p. 1, doi. 10.1155/2020/9387560

By:

Hou, Shule;
Chen, Penghui;
Chen, Jiarui;
Chen, Junmin;
Sun, Lianhua;
Chen, Jianyong;
He, Baihui;
Li, Yue;
Qin, Huan;
Hong, Yuren;
Li, Shuna;
He, Jingchun;
Gao, Dekun;
Mammano, Fabio;
Yang, Jun

Publication type:

Article

The Influence of Cochlear Implant-Based Electric Stimulation on the Electrophysiological Characteristics of Cultured Spiral Ganglion Neurons.

Published in:

Neural Plasticity, 2020, p. 1, doi. 10.1155/2020/3108490

By:

Shen, Na;
Zhou, Lei;
Lai, Bin;
Li, Shufeng

Publication type:

Article

Atrial Natriuretic Peptide Improves Neurite Outgrowth from Spiral Ganglion Neurons In Vitro through a cGMP-Dependent Manner.

Published in:

Neural Plasticity, 2020, p. 1, doi. 10.1155/2020/8831735

By:

Sun, Fei;
Zhou, Ke;
Tian, Ke-yong;
Wang, Jie;
Qiu, Jian-hua;
Zha, Ding-jun

Publication type:

Article

Atrial Natriuretic Peptide Improves Neurite Outgrowth from Spiral Ganglion Neurons In Vitro through a cGMP-Dependent Manner.

Published in:

Neural Plasticity, 2020, p. 1, doi. 10.1155/2020/8831735

By:

Sun, Fei;
Zhou, Ke;
Tian, Ke-yong;
Wang, Jie;
Qiu, Jian-hua;
Zha, Ding-jun

Publication type:

Article

486 Molecular Mechanisms of Type II Spiral Ganglion Neuron Development.

Published in:

2023

By:

George, Deborah Jane;
Mejia, Juliet;
Thiru, Shankar;
Deans, Michael;
Coate, Thomas

Publication type:

Abstract

485 Modeling gastric mucus layer physiology using human organoids.

Published in:

2023

By:

Lyon, Katrina;
Sidar, Barkan;
Dudiak, Cam;
Wilking, Jim;
Bansil, Rama;
Bimczok, Diane

Publication type:

Abstract

The Evaluation of GJB2 Gene Expression in the Cochlear Tissue Exposed to White Noise.

Published in:

Journal of Health & Safety at Work, 2022, v. 12, n. 1, p. 25

By:

Khadem, Monireh;
Rad, Elham Kazemi;
Esmaeilpoor, Mohammad Reza Monazzam;
Hotkani, Maryam Mirzaei;
Mozaffari, Sajjad;
Garmaroudi, Amir Abbasi

Publication type:

Article

Simvastatin Results in a Dose-Dependent Toxic Effect on Spiral Ganglion Neurons in an In Vitro Organotypic Culture Assay.

Published in:

BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/3580359

By:

Leitmeyer, Katharina;
Glutz, Andrea;
Setz, Cristian;
Wieland, Leonie;
Egloff, Sulamith;
Bodmer, Daniel;
Brand, Yves

Publication type:

Article

Hypoxia Induces a Metabolic Shift and Enhances the Stemness and Expansion of Cochlear Spiral Ganglion Stem/Progenitor Cells.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/359537

By:

Chen, Hsin-Chien;
Lee, Jen-Tin;
Shih, Cheng-Ping;
Chao, Ting-Ting;
Sytwu, Huey-Kang;
Li, Shiue-Li;
Fang, Mei-Cho;
Chen, Hang-Kang;
Lin, Yi-Chun;
Kuo, Chao-Yin;
Wang, Chih-Hung

Publication type:

Article

Inhibition of mTOR by Rapamycin Results in Auditory Hair Cell Damage and Decreased Spiral Ganglion Neuron Outgrowth and Neurite Formation In Vitro.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/925890

By:

Leitmeyer, Katharina;
Glutz, Andrea;
Radojevic, Vesna;
Setz, Cristian;
Huerzeler, Nathan;
Bumann, Helen;
Bodmer, Daniel;
Brand, Yves

Publication type:

Article

Evaluation of Ototoxic Effects of Cisplatin in a Rat Model: A Dose–Response Study.

Published in:

Applied Sciences (2076-3417), 2025, v. 15, n. 3, p. 1090, doi. 10.3390/app15031090

By:

Hellies, Filippo;
Fracaro, Silvia;
Pintus, Giovanni;
Simoni, Edi;
Gentilin, Erica;
Marioni, Gino;
Martini, Alessandro;
Nicolai, Piero;
Zanoletti, Elisabetta;
Albertin, Giovanna;
Astolfi, Laura

Publication type:

Article

Distribution of Immune Cells Including Macrophages in the Human Cochlea.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.781702

By:

Liu, Wei;
Danckwardt-Lillieström, Niklas;
Schrott-Fischer, Anneliese;
Glueckert, Rudolf;
Rask-Andersen, Helge

Publication type:

Article

Comparison of Drug Availability in the Inner Ear After Oral, Transtympanic, and Combined Administration.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.641593

By:

Li, Yang;
Kanzaki, Sho;
Shibata, Shinsuke;
Nakamura, Masaya;
Ozaki, Masahiro;
Okano, Hideyuki;
Ogawa, Kaoru

Publication type:

Article

Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons.

Published in:

Iranian Journal of Basic Medical Sciences, 2023, v. 26, n. 12, p. 1423, doi. 10.22038/IJBMS.2023.69190.15076

By:

Hongxia Wu;
Yangxi Ou;
Siji Wang;
Fenghui Yu;
Xiaoxia Fan;
Houyong Kang;
Tao Chen

Publication type:

Article

Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153957

By:

Inagaki, Yozo;
Fujioka, Masato;
Kanzaki, Sho;
Watanabe, Kotaro;
Oishi, Naoki;
Itakura, Go;
Yasuda, Akimasa;
Shibata, Shinsuke;
Nakamura, Masaya;
Okano, Hirotaka James;
Okano, Hideyuki;
Ogawa, Kaoru

Publication type:

Article

Corrigendum: Potentiation of brain-derived neurotrophic factor-induced protection of spiral ganglion neurons by C3 exoenzyme/Rho inhibitor.

Published in:: Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.1078962
Publication type:: Article

Cellular autophagy, the compelling roles in hearing function and dysfunction.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 01, doi. 10.3389/fncel.2022.966202

By:

Huanzhi Wan;
Yuanyuan Zhang;
Qingquan Hua

Publication type:

Article

Profiling mouse cochlear cell maturation using 10× Genomics single-cell transcriptomics.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.962106

By:

Zhenhang Xu;
Shu Tu;
Pass, Caroline;
Yan Zhang;
Huizhan Liu;
Diers, Jack;
Yusi Fu;
He, David Z. Z.;
Jian Zuo

Publication type:

Article

Glutathione Peroxidase 1 Protects Against Peroxynitrite-Induced Spiral Ganglion Neuron Damage Through Attenuating NF-κB Pathway Activation.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.841731

By:

Wang, Xue;
Han, Yuechen;
Chen, Fang;
Wang, Man;
Xiao, Yun;
Wang, Haibo;
Xu, Lei;
Liu, Wenwen

Publication type:

Article

Mechanism and Prevention of Spiral Ganglion Neuron Degeneration in the Cochlea.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fncel.2021.814891

By:

Zhang, Li;
Chen, Sen;
Sun, Yu

Publication type:

Article

Physiopathological Relevance of D-Serine in the Mammalian Cochlea.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.733004

By:

Wang, Jing;
Serratrice, Nicolas;
Lee, Cindy J.;
François, Florence;
Sweedler, Jonathan V.;
Puel, Jean-Luc;
Mothet, Jean-Pierre;
Ruel, Jérôme

Publication type:

Article

Autophagy Regulates the Survival of Hair Cells and Spiral Ganglion Neurons in Cases of Noise, Ototoxic Drug, and Age-Induced Sensorineural Hearing Loss.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.760422

By:

Guo, Lingna;
Cao, Wei;
Niu, Yuguang;
He, Shuangba;
Chai, Renjie;
Yang, Jianming

Publication type:

Article

Electrically evoked compound action potentials in cochlear implant users with preoperative residual hearing.

Published in:

Frontiers in Human Neuroscience, 2023, p. 01, doi. 10.3389/fnhum.2023.1125747

By:

Liebscher, Tim;
Hornung, Joachim;
Hoppe, Ulrich

Publication type:

Article