Works matching DE "SPIRAL ganglion"

Results: 243

Volumetric atlas of the rat inner ear from microCT and iDISCO+ cleared temporal bones.

Published in:

PeerJ, 2025, p. 1, doi. 10.7717/peerj.19512

By:

Cossellu, Daniele;
Vivado, Elisa;
Batti, Laura;
Gantar, Ivana;
Pizzala, Roberto;
Perin, Paola

Publication type:

Article

FGF13 prevents age-related hearing loss by protecting spiral ganglion neurons and ribbon synapses from injury.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02607-5

By:

Yin, Huan;
Cao, Huan;
Yang, Jianwang;
Liu, Tao;
Li, Qi;
Liu, Mengxiao;
Wang, Baoshan

Publication type:

Article

Influence of Cochlear Anatomy on Intraoperative Electrically Evoked Compound Action Potentials.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 16, p. 4716, doi. 10.3390/jcm13164716

By:

Fatani, Nawaf;
Abdelsamad, Yassin;
Alsanosi, Abdulrahman

Publication type:

Article

Current Advances in Gene Therapies of Genetic Auditory Neuropathy Spectrum Disorder.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 3, p. 738, doi. 10.3390/jcm12030738

By:

Saidia, Anissa Rym;
Ruel, Jérôme;
Bahloul, Amel;
Chaix, Benjamin;
Venail, Frédéric;
Wang, Jing

Publication type:

Article

Oxidative Stress Plays an Important Role in Glutamatergic Excitotoxicity-Induced Cochlear Synaptopathy: Implication for Therapeutic Molecules Screening.

Published in:

Antioxidants, 2024, v. 13, n. 2, p. 149, doi. 10.3390/antiox13020149

By:

Saidia, Anissa Rym;
François, Florence;
Casas, François;
Mechaly, Ilana;
Venteo, Stéphanie;
Veechi, Joseph T.;
Ruel, Jérôme;
Puel, Jean-Luc;
Wang, Jing

Publication type:

Article

Fasudil protects spiral ganglion neurons and hair cells against cisplatin-induced apoptosis by inhibiting reactive oxygen species accumulation and regulating the ROCK/PTEN/AKT signaling pathway.

Published in:

Toxicology Research, 2025, v. 14, n. 2, p. 1, doi. 10.1093/toxres/tfaf030

By:

Yin, Peng;
Jiang, Zhenhua;
Wang, Xue;
Gong, Shusheng;
Zhang, Cui;
Fan, Zhaomin

Publication type:

Article

Electrical equivalent circuit for analyzing the effect of signal shape on power distribution in cochlear implant electrodes and surrounding tissue.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-04840-5

By:

Sehlmeyer, Merle;
Makarenko, Mariia;
Schoerner, Nele;
Bhavsar, Mit B.;
Blank, Tatiana;
Maier, Hans Jürgen;
Kral, Andrej;
Maier, Hannes;
Zimmermann, Stefan

Publication type:

Article

3D virtual histology of rodent and primate cochleae with multi-scale phase-contrast X-ray tomography.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-89431-0

By:

Schaeper, Jannis J.;
Kampshoff, Christoph A.;
Wolf, Bettina J.;
Roos, Lennart;
Michanski, Susann;
Ruhwedel, Torben;
Eckermann, Marina;
Meyer, Alexander;
Jeschke, Marcus;
Wichmann, Carolin;
Moser, Tobias;
Salditt, Tim

Publication type:

Article

Studies on the mechanism of ototoxic action of cisplatin and the antagonistic effect of polyphenolic compounds.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1586243

By:

Han, Shengyu;
Sun, Jinjun;
Li, Wenpeng;
Li, Jihong;
Yu, Haoming;
Wang, Shuai;
Chi, Yuhua

Publication type:

Article

FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1462421

By:

Wang, Fan;
Xu, Yue;
Wang, Yajie;
Liu, Qian;
Li, Yanan;
Zhang, Weiwei;
Nong, Huiming;
Zhang, Junhong;
Zhao, Hao;
Yang, Huaqian;
Guo, Lingchuan;
Li, Jianfeng;
Li, Hong;
Yang, Qianqian

Publication type:

Article

The chiisanoside derivatives present in the leaves of Acanthopanax sessiliflorus activate autophagy through the LRP6/GSK3β axis and thereafter inhibit oxidative stress, thereby counteracting cisplatin-induced ototoxicity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1518810

By:

Zhang, Wenxin;
Teng, Hongbo;
Zhao, Tianyi;
Eglitis, Roberts I.;
Wang, Xv;
Yu, Zhengxuan;
Qu, Shurong;
Wang, Haijing;
Zhao, Yaru;
Fan, Bowen;
Liu, Shuangli;
Zhao, Yan

Publication type:

Article

6’-sialyllactose ameliorates the ototoxic effects of the aminoglycoside antibiotic neomycin in susceptible mice.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1264060

By:

Assale, Tawfik Abou;
Kuenzel, Thomas;
Schink, Tamara;
Shahraz, Anahita;
Neumann, Harald;
Klaus, Christine

Publication type:

Article

Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1125948

By:

Al Aameri, Raheem F. H.;
Alanisi, Entkhab M. A.;
Oluwatosin, Adu;
Al Sallami, Dheyaa;
Sheth, Sandeep;
Alberts, Ian;
Patel, Shree;
Rybak, Leonard P.;
Ramkumar, Vickram

Publication type:

Article

HIF-1α as a Target Molecule in the Use of Triazino-Indole Derivative on the Acoustic Trauma Model.

Published in:

Audiology Research, 2021, v. 11, n. 3, p. 365, doi. 10.3390/audiolres11030034

By:

Pastushenkov, Vladimir L.;
Buynov, Leonid G.;
Kuznetsov, Maksim S.;
Dvorianchikov, Vladimir V.;
Glaznikov, Lev A.;
Pastushenkov, Aleksandr L.

Publication type:

Article

Meta-Analysis--Correlation between Spiral Ganglion Cell Counts and Speech Perception with a Cochlear Implant.

Published in:

Audiology Research, 2021, v. 11, n. 2, p. 220, doi. 10.3390/audiolres11020020

By:

Yew-Song Cheng;
Svirsky, Mario A.

Publication type:

Article

Purification of Fibroblasts From the Spiral Ganglion.

Published in:

Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.877342

By:

Anacker, Annett;
Esser, Karl-Heinz;
Lenarz, Thomas;
Paasche, Gerrit

Publication type:

Article

In silico Single-Cell Analysis of Steroid-Responsive Gene Targets in the Mammalian Cochlea.

Published in:

Frontiers in Neurology, 2022, v. 12, p. 1, doi. 10.3389/fneur.2021.818157

By:

Nelson, Lacey;
Lovett, Braeden;
Johns, J. Dixon;
Gu, Shoujun;
Choi, Dongseok;
Trune, Dennis;
Hoa, Michael

Publication type:

Article

Distribution of Immune Cells Including Macrophages in the Human Cochlea.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.781702

By:

Liu, Wei;
Danckwardt-Lillieström, Niklas;
Schrott-Fischer, Anneliese;
Glueckert, Rudolf;
Rask-Andersen, Helge

Publication type:

Article

Comparison of Drug Availability in the Inner Ear After Oral, Transtympanic, and Combined Administration.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.641593

By:

Li, Yang;
Kanzaki, Sho;
Shibata, Shinsuke;
Nakamura, Masaya;
Ozaki, Masahiro;
Okano, Hideyuki;
Ogawa, Kaoru

Publication type:

Article

AIF knockdown induce apoptosis and mitochondrial dysfunction in cochlear spiral ganglion neurons in vitro.

Published in:

Molecular Medicine Reports, 2020, v. 21, n. 4, p. 1910, doi. 10.3892/mmr.2020.10970

By:

Zong, Liang;
Zhao, Jiandong;
Wu, Wenming;
Wang, Jialing;
Huang, Deliang;
Liu, Mingbo

Publication type:

Article

Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 1, p. 228, doi. 10.3892/mmr.2016.6010

By:

CHENG ZHONG;
XUEYUAN ZHANG

Publication type:

Article

Thiol-Disulfide Homeostasis in Noise-Induced Hearing Loss in Rats.

Published in:

Journal of International Advanced Otology, 2024, v. 20, n. 6, p. 466, doi. 10.5152/iao.2024.241555

By:

Aydın, Enes;
Durankaya, Serpil Mungan;
Yilmaz, Osman;
Kirkim, Günay;
Aktaş, Safiye;
Neşelioğlu, Salim;
Erel, Özcan;
Olgun, Yüksel;
Dalgıç, Abdullah

Publication type:

Article

Comparison of Cytotoxic and Ototoxic Effects of Lipoplatin and Cisplatin in Neuroblastoma In Vivo Tumor Model.

Published in:

Journal of International Advanced Otology, 2022, v. 18, n. 5, p. 392, doi. 10.5152/iao.2022.21268

By:

Eskicioğlu, Hande Evin;
Olgun, Yüksel;
Aktaş, Tekincan Çağrı;
Aktas, Safiye;
Kolatan, Efsun;
Serinan, Efe;
Altun, Zekiye;
Kırkım, Günay;
Yılmaz, Osman;
Olgun, Nur

Publication type:

Article

The Spatiotemporal Expression of Ring1B in the Postnatal Mouse Cochlea.

Published in:

Journal of International Advanced Otology, 2022, v. 18, n. 4, p. 297, doi. 10.5152/iao.2022.21473

By:

Linhui Li;
Yuanping Xiong;
Bin Chen;
Yazhi Xing

Publication type:

Article

Oleuropein Effect on Noise-Induced Hearing Loss.

Published in:

Journal of International Advanced Otology, 2022, v. 18, n. 2, p. 118, doi. 10.5152/iao.2022.20009

By:

Kümüş, Özgür;
Olgun, Yüksel;
Durankaya, Serpil Mungan;
Aktaş, Safiye;
Kirkim, Günay;
Sütay, Semih

Publication type:

Article

Literature Review on the Distribution of Spiral Ganglion Cell Bodies inside the Human Cochlear Central Modiolar Trunk.

Published in:

Journal of International Advanced Otology, 2020, v. 16, n. 2, p. 104, doi. 10.5152/iao.2020.7510

By:

Dhanasingh, Anandhan;
Jolly, Claude N.;
Rajan, Gunesh;
van de Heyning, Paul

Publication type:

Article

Literature Review on the Distribution of Spiral Ganglion Cell Bodies inside the Human Cochlear Central Modiolar Trunk.

Published in:

Journal of International Advanced Otology, 2020, v. 16, n. 1, p. 104, doi. 10.5152/iao.2020.7510

By:

Dhanasingh, Anandhan;
Jolly, Claude N.;
Rajan, Gunesh;
van de Heyning, Paul

Publication type:

Article

Mitochonic acid 5 mitigates age-related hearing loss progression by targeting defective 2-methylthiolation in mitochondrial transfer RNAs.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1541347

By:

Kouga, Teppei;
Miwa, Toru;
Wei, Fan-yan;
Sunami, Kishiko;
Tomizawa, Kazuhito

Publication type:

Article

N <sup>1</sup>-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1542164

By:

Miwa, Toru;
Tarui, Akihito;
Kouga, Teppei;
Asai, Yasunori;
Ogita, Hideaki;
Fujikawa, Taro;
Hakuba, Nobuhiro

Publication type:

Article

Local delivery of soluble fractalkine (CX3CL1) peptide restores ribbon synapses after noise-induced cochlear synaptopathy.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1486740

By:

Manickam, Vijayprakash;
Maity, Sibaprasad;
Murali, Sree Varshini;
Gawande, Dinesh Y.;
Stothert, Andrew R.;
Batalkina, Lyudamila;
Cardona, Astrid E.;
Kaur, Tejbeer

Publication type:

Article

Noise-induced cochlear synaptopathy in C57BL/6â€‰ N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1465216

By:

Blum, Kerstin;
Schepsky, Pauline;
Derleder, Philip;
Schätzle, Philipp;
Nasri, Fahmi;
Fischer, Philipp;
Engel, Jutta;
Kurt, Simone

Publication type:

Article

Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1465216

By:

Blum, Kerstin;
Schepsky, Pauline;
Derleder, Philip;
Schätzle, Philipp;
Nasri, Fahmi;
Fischer, Philipp;
Engel, Jutta;
Kurt, Simone

Publication type:

Article

Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1465216

By:

Blum, Kerstin;
Schepsky, Pauline;
Derleder, Philip;
Schätzle, Philipp;
Nasri, Fahmi;
Fischer, Philipp;
Engel, Jutta;
Kurt, Simone

Publication type:

Article

Age-related alterations in efferent medial olivocochlear-outer hair cell and primary auditory ribbon synapses in CBA/J mice.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1412450

By:

Dörje, Nele Marie;
Shvachiy, Liana;
Kück, Fabian;
Outeiro, Tiago F.;
Strenzke, Nicola;
Beutner, Dirk;
Setz, Cristian

Publication type:

Article

Cyclic AMP signaling promotes regeneration of cochlear synapses after excitotoxic or noise trauma.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1363219

By:

Hemachandran, Sriram;
Ning Hu;
Kane, Catherine J.;
Green, Steven H.

Publication type:

Article

The transcription factor Pou4f3 is essential for the survival of postnatal and adult mouse cochlear hair cells and normal hearing.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1369282

By:

Singh, Jarnail;
Randle, Michelle R.;
Walters, Bradley J.;
Cox, Brandon C.

Publication type:

Article

Spiral ganglion neuron degeneration in aminoglycoside-deafened rats involves innate and adaptive immune responses not requiring complement.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1389816

By:

Gansemer, Benjamin M.;
Rahman, Muhammad T.;
Zhenshen Zhang;
Green, Steven H.

Publication type:

Article

Tinnitus Footprints in the Cochlea.

Published in:

International Tinnitus Journal, 2023, v. 27, n. 1, p. 54, doi. 10.5935/0946-5448.20230009

By:

Costa Pires de Oliveira, Carlos Augusto;
Moura Kehrle, Helga;
Campos Granjeiro, Ronaldo;
Sarmento de Oliveira, Taciana;
Teixeira, Maria Cristina;
da Silva Murad, Jose Elias;
Moreira Cardoso Severino, Miriã

Publication type:

Article

Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2020.

Published in:

Neural Plasticity, 2021, p. 1, doi. 10.1155/2021/9897461

By:

Chai, Renjie;
Li, Geng-lin;
Wang, Jian;
Zou, Jing;
Huang, Hai

Publication type:

Article

Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 41, p. 8013, doi. 10.1523/jneurosci.1740-19.2019

By:

Ghimire, Satish R.;
Deans, Michael R.

Publication type:

Article

Pou4fl Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca2+ Signaling.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 27, p. 5284, doi. 10.1523/jneurosci.2728-18.2019

By:

Sherrill, Hanna E.;
Jean, Philippe;
Driver, Elizabeth C.;
Sanders, Tessa R.;
Fitzgerald, Tracy S.;
Moser, Tobias;
Kelley, Matthew W.

Publication type:

Article

Selective Deletion of Cochlear Hair Cells Causes Rapid Age-Dependent Changes in Spiral Ganglion and Cochlear Nucleus Neurons.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 20, p. 7878, doi. 10.1523/JNEUROSCI.2179-14.2015

By:

Ling Tong;
Strong, Melissa K.;
Kaur, Tejbeer;
Juiz, Jose M.;
Oesterle, Elizabeth C.;
Hume, Clifford;
Warchol, Mark E.;
Palmiter, Richard D.;
Rubel, Edwin W.

Publication type:

Article

Spiral Ganglion Degeneration and Hearing Loss as a Consequence of Satellite Cell Death in Saposin B-Deficient Mice.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 7, p. 3263, doi. 10.1523/JNEUROSCI.3920-13.2015

By:

Akil, Omar;
Ying Sun;
Vijayakumar, Sarath;
Wujuan Zhang;
Ku, Tiffany;
Chi-Kyou Lee;
Jones, Sherri;
Grabowski, Gregory A.;
Lustig, Lawrence R.

Publication type:

Article

Unmasking of Spiral Ganglion Neuron Firing Dynamics by Membrane Potential and Neurotrophin-3.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 29, p. 9688, doi. 10.1523/JNEUROSCI.4552-13.2014

By:

Crozier, Robert A.;
Davis, Robin L.

Publication type:

Article

Exosomes derived from cochlear spiral ganglion progenitor cells prevent cochlea damage from ischemia-reperfusion injury via inhibiting the inflammatory process.

Published in:

Cell & Tissue Research, 2021, v. 386, n. 2, p. 239, doi. 10.1007/s00441-021-03468-x

By:

Yang, Tao;
Cai, Cuiyun;
Peng, Anquan;
Liu, Jia;
Wang, Qin

Publication type:

Article

Npr2 null mutants show initial overshooting followed by reduction of spiral ganglion axon projections combined with near-normal cochleotopic projection.

Published in:

Cell & Tissue Research, 2019, v. 378, n. 1, p. 15, doi. 10.1007/s00441-019-03050-6

By:

Schmidt, Hannes;
Fritzsch, Bernd

Publication type:

Article

Apelin-13 protects against cisplatin-induced ototoxicity by inhibiting apoptosis and regulating STAT1 and STAT3.

Published in:

Archives of Toxicology, 2023, v. 97, n. 9, p. 2477, doi. 10.1007/s00204-023-03544-x

By:

Yin, Haiyan;
Sun, Yinuo;
Ya, Bailiu;
Guo, Yan;
Zhao, Hao;
Zhang, Lili;
Wang, Fan;
Zhang, Weiwei;
Yang, Qianqian

Publication type:

Article

The expression of PHB2 in the cochlea: Possible relation to age‐related hearing loss.

Published in:

Cell Biology International, 2021, v. 45, n. 12, p. 2490, doi. 10.1002/cbin.11693

By:

Yu, Xiaoyu;
Guan, Ming;
Shang, Haiqiong;
Teng, Yaoshu;
Gao, Yueqiu;
Wang, Bin;
Ma, Zhiqi;
Cao, Xiaolin;
Li, Yong

Publication type:

Article

Next-Generation Sequencing of Chinese Children with Congenital Hearing Loss Reveals Rare and Novel Variants in Known and Candidate Genes.

Published in:

Biomedicines, 2024, v. 12, n. 12, p. 2657, doi. 10.3390/biomedicines12122657

By:

Jin, Yuan;
Liu, Xiaozhou;
Zhang, Qiong;
Xiong, Ying;
Hu, Yao;
He, Haixia;
Chen, Wei;
Sun, Yu

Publication type:

Article

Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss.

Published in:

Biomedicines, 2023, v. 11, n. 12, p. 3347, doi. 10.3390/biomedicines11123347

By:

Lye, Joey;
Delaney, Derek S.;
Leith, Fiona K.;
Sardesai, Varda S.;
McLenachan, Samuel;
Chen, Fred K.;
Atlas, Marcus D.;
Wong, Elaine Y. M.

Publication type:

Article