Works matching DE "SPHINGOSINE-1-phosphate"

Results: 844

Etrasimod: Modulating Sphingosine-1-Phosphate Receptors to Treat Ulcerative Colitis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 11, p. 3890, doi. 10.3390/jcm14113890

By:

Martinez-Molina, Cristina;
González-Suárez, Begoña

Publication type:

Article

Macrophage S1PR2 Drives Sepsis-induced Immunosuppression by Exacerbating Mitochondrial Fragmentation.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 72, n. 6, p. 615, doi. 10.1165/rcmb.2024-0161OC

By:

Yu, Xiangyang;
Hu, Xin;
Wang, Dongdong;
Cui, Ping;
Zeng, Min;
Li, Min;
Gong, Chenchen;
Huang, Dongqin;
Wang, Yan;
Zhang, Kai;
Fang, Xiangming

Publication type:

Article

The Current Sphingosine 1 Phosphate Receptor Modulators in the Management of Ulcerative Colitis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 10, p. 3475, doi. 10.3390/jcm14103475

By:

Choon, Xin Yi;
Yeo, Jie Han;
White, Christopher;
Sharma, Esha;
Samaan, Mark A.

Publication type:

Article

Recent advances in the field of ovarian tissue cryopreservation and opportunities for research.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 6, p. 709, doi. 10.1007/s10815-017-0899-1

By:

Ladanyi, Camille;
Mor, Amir;
Christianson, Mindy;
Dhillon, Namisha;
Segars, James

Publication type:

Article

Iron excess upregulates SPNS2 mRNA levels but reduces sphingosine-1-phosphate export in human osteoblastic MG-63 cells.

Published in:

Osteoporosis International, 2018, v. 29, n. 8, p. 1905, doi. 10.1007/s00198-018-4531-8

By:

Peltier, L.;
Bendavid, C.;
Cavey, T.;
Island, M.-L.;
Doyard, M.;
Leroyer, P.;
Allain, C.;
De Tayrac, M.;
Ropert, M.;
Loréal, O.;
Guggenbuhl, P.

Publication type:

Article

Fingolimod affects gene expression profile associated with LPS-induced memory impairment.

Published in:

Experimental Brain Research, 2014, v. 232, n. 11, p. 3687, doi. 10.1007/s00221-014-4052-4

By:

Omidbakhsh, Rana;
Rajabli, Banafshe;
Nasoohi, Sanaz;
Khallaghi, Behzad;
Mohamed, Zahurin;
Naidu, Murali;
Ahmadiani, Abolhassan;
Dargahi, Leila

Publication type:

Article

Deficiency of the sphingosine-1-phosphate (S1P) transporter Mfsd2b protects the heart against hypertension-induced cardiac remodeling by suppressing the L-type-Ca2+ channel.

Published in:

Basic Research in Cardiology, 2024, v. 119, n. 5, p. 853, doi. 10.1007/s00395-024-01073-x

By:

Duse, Dragos Andrei;
Schröder, Nathalie Hannelore;
Srivastava, Tanu;
Benkhoff, Marcel;
Vogt, Jens;
Nowak, Melissa Kim;
Funk, Florian;
Semleit, Nina;
Wollnitzke, Philipp;
Erkens, Ralf;
Kötter, Sebastian;
Meuth, Sven Günther;
Keul, Petra;
Santos, Webster;
Polzin, Amin;
Kelm, Malte;
Krüger, Martina;
Schmitt, Joachim;
Levkau, Bodo

Publication type:

Article

Insights From Long-term Follow-up of a Girl With Adrenal Insufficiency and Sphingosine-1-Phosphate Lyase Deficiency.

Published in:

Journal of the Endocrine Society, 2022, v. 6, n. 5, p. 1, doi. 10.1210/jendso/bvac020

By:

Maharaj, Avinaash;
Güran, Tülay;
Buonocore, Federica;
Achermann, John C;
Metherell, Louise;
Prasad, Rathi;
Çetinkaya, Semra

Publication type:

Article

In Systemic Sclerosis, a Unique Long Non Coding RNA Regulates Genes and Pathways Involved in the Three Main Features of the Disease (Vasculopathy, Fibrosis and Autoimmunity) and in Carcinogenesis.

Published in:

Journal of Clinical Medicine, 2019, p. 320, doi. 10.3390/jcm8030320

By:

Dolcino, Marzia;
Tinazzi, Elisa;
Puccetti, Antonio;
Lunardi, Claudio

Publication type:

Article

The Sphingosine 1‐Phosphate Analogue FTY720 Alleviates Seizure‐induced Overexpression of P‐Glycoprotein in Rat Hippocampus.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2018, v. 123, n. 1, p. 14, doi. 10.1111/bcpt.12973

By:

Gao, Fei;
Gao, Ying;
Meng, Fangling;
Yang, Chunmei;
Fu, Jiangfeng;
Li, Yajun

Publication type:

Article

Effect of Ponesimod, a Selective S1P1 Receptor Modulator, on the QT Interval in Healthy Individuals.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 5, p. 429, doi. 10.1111/bcpt.12336

By:

Hoch, Matthias;
Darpo, Borje;
Brossard, Patrick;
Zhou, Meijian;
Stoltz, Randall;
Dingemanse, Jasper

Publication type:

Article

S1P in the development of atherosclerosis: roles of hemodynamic wall shear stress and endothelial permeability.

Published in:

Tissue Barriers, 2021, v. 9, n. 4, p. 1, doi. 10.1080/21688370.2021.1959243

By:

Warboys, Christina M;
Weinberg, Peter D

Publication type:

Article

Barrier maintenance by S1P during inflammation and sepsis.

Published in:

Tissue Barriers, 2021, v. 9, n. 4, p. 1, doi. 10.1080/21688370.2021.1940069

By:

Ziegler, Anke C.;
Gräler, Markus H.

Publication type:

Article

Characterization of NK cells in patients with multiple sclerosis under sphingosine-1-phosphate receptor 1 (S1P1) antagonist therapy.

Published in:

Turkish Journal of Immunology, 2016, v. 4, p. 28

By:

Acar, Nazire Pınar;
Sayat, Guliz;
Karabudak, Rana;
Tuncer, Asli;
Özkazanç, Didem;
Esendagli, Gunes

Publication type:

Article

S1P1 deletion differentially affects TH17 and regulatory T cells.

Published in:

Turkish Journal of Immunology, 2016, v. 4, p. 21

By:

Eken, Ahmet;
Duhen, Rebekka;
Bettelli, Estelle;
Singh, Akhilesh K.;
Fry, Mallory;
Oukka, Mohamed;
Buckner, Jane H.;
Kita, Mariko

Publication type:

Article

Expression of sphingosine-1-phosphate receptor 2 is correlated with migration and invasion of human colon cancer cells: A preliminary clinical study.

Published in:

Oncology Letters, 2022, v. 24, n. 1, p. N.PAG, doi. 10.3892/ol.2022.13361

By:

Yan, Junjun;
Chen, Yi;
Wu, Qibiao;
Shao, Le;
Zhou, Xiqiao

Publication type:

Article

Activation of the SphK1/ERK/p‑ERK pathway promotes autophagy in colon cancer cells.

Published in:

Oncology Letters, 2018, v. 15, n. 6, p. 9719, doi. 10.3892/ol.2018.8588

By:

Xu, Chunyan;
Zhang, WENlu;
Liu, Shiquan;
Wu, WENhong;
Qin, MENgbin;
Huang, Jiean

Publication type:

Article

Potential signaling pathway involved in sphingosine-1-phosphate-induced epithelial-mesenchymal transition in cancer (Review).

Published in:

Oncology Letters, 2016, v. 12, n. 1, p. 379, doi. 10.3892/ol.2016.4661

By:

YE ZENG;
XING-HONG YAO;
ZHI-PING YAN;
JING-XIA LIU;
XIAO-HENG LIU

Publication type:

Article

Sphingosine-1-phosphate Treatment Improves Cryopreservation Efficiency in Human Mesenchymal Stem Cells.

Published in:

Life (2075-1729), 2023, v. 13, n. 6, p. 1286, doi. 10.3390/life13061286

By:

Oh, Seong-Ju;
Jo, Chan-Hee;
Kim, Tae-Seok;
Hong, Chae-Yeon;
Lee, Sung-Lim;
Kang, Young-Hoon;
Rho, Gyu-Jin

Publication type:

Article

Anti-Inflammatory Effect of Geniposide on Regulating the Functions of Rheumatoid Arthritis Synovial Fibroblasts via Inhibiting Sphingosine-1-Phosphate Receptors1/3 Coupling Gαi/Gαs Conversion.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.584176

By:

Wang, Rong-hui;
Dai, Xue-jing;
Wu, Hong;
Wang, Meng-die;
Deng, Ran;
Wang, Yan;
Bu, Yan-hong;
Sun, Ming-hui;
Zhang, Heng

Publication type:

Article

Coix Seed Oil Exerts an Anti–Triple-Negative Breasty Cancer Effect by Disrupting miR-205/S1PR1 Axis.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.529962

By:

Fang, Ting;
Jiang, Yi-Xin;
Chen, Long;
Huang, Ling;
Tian, Xin-Hui;
Zhou, Yu-Dong;
Nagle, Dale G.;
Zhang, Dan-Dan

Publication type:

Article

In silico Docking Studies of Fingolimod and S1P1 Agonists.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00247

By:

Marciniak, Alexander;
Camp, Sara M.;
Garcia, Joe G. N.;
Polt, Robin

Publication type:

Article

Non-Mitogenic Fibroblast Growth Factor 1 Enhanced Angiogenesis Following Ischemic Stroke by Regulating the Sphingosine-1-Phosphate 1 Pathway.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00059

By:

Zou, Yuchi;
Hu, Jian;
Huang, Wenting;
Ye, Shasha;
Han, Fanyi;
Du, Jingting;
Shao, Mingjie;
Guo, Ruili;
Lin, Jingjing;
Zhao, Yeli;
Xiong, Ye;
Wang, Xue

Publication type:

Article

Sphingosine-1-Phosphate Receptors Modulators Decrease Signs of Neuroinflammation and Prevent Parkinson's Disease Symptoms in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00077

By:

Pépin, Élise;
Jalinier, Tim;
Lemieux, Guillaume L.;
Massicotte, Guy;
Cyr, Michel

Publication type:

Article

Sphingosine-1-Phosphate (S-1P) Promotes Differentiation of Naive Macrophages and Enhances Protective Immunity Against Mycobacterium tuberculosis.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2019.03085

By:

Nadella, Vinod;
Sharma, Lalita;
Kumar, Pankaj;
Gupta, Pushpa;
Gupta, Umesh D.;
Tripathi, Srikant;
Pothani, Suresh;
Qadri, S. S. Y. H.;
Prakash, Hridayesh

Publication type:

Article

Sphingosine-1-Phosphate and Macrophage Biology—How the Sphinx Tames the Big Eater.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01706

By:

Weigert, Andreas;
Olesch, Catherine;
Brüne, Bernhard

Publication type:

Article

The Intra-nuclear SphK2-S1P Axis Facilitates M1-to-M2 Shift of Microglia via Suppressing HDAC1-Mediated KLF4 Deacetylation.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01241

By:

Ji, Juan;
Wang, Juan;
Yang, Jin;
Wang, Xi-Peng;
Huang, Jing-Jing;
Xue, Teng-Fei;
Sun, Xiu-Lan

Publication type:

Article

Halted Lymphocyte Egress via Efferent Lymph Contributes to Lymph Node Hypertrophy During Hypercholesterolemia.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00575

By:

Tay, Meng Hwee Daniel;
Lim, Swee Yeng Jason;
Leong, Yew Fai Ivan;
Thiam, Chung Hwee;
Tan, Kar Wai;
Torta, Federico Tesio;
Narayanaswamy, Pradeep;
Wenk, Markus;
Angeli, Véronique

Publication type:

Article

Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00217

By:

Eken, Ahmet;
Yetkin, Mehmet Fatih;
Vural, Alperen;
Okus, Fatma Zehra;
Erdem, Serife;
Azizoglu, Zehra Busra;
Haliloglu, Yesim;
Cakir, Mustafa;
Turkoglu, Enes Mehmet;
Kilic, Omer;
Kara, Irfan;
Dönmez Altuntaş, Hamiyet;
Oukka, Mohamed;
Kutuk, Mehmet Serdar;
Mirza, Meral;
Canatan, Halit

Publication type:

Article

Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02189

By:

Mike, Elise V.;
Makinde, Hadijat M.;
Der, Evan;
Stock, Ariel;
Gulinello, Maria;
Gadhvi, Gaurav T.;
Winter, Deborah R.;
Cuda, Carla M.;
Putterman, Chaim

Publication type:

Article

Immunohistochemical detection of sphingosine-1-phosphate receptor 1 and 5 in human multiple sclerosis lesions.

Published in:

Neuropathology & Applied Neurobiology, 2014, v. 40, n. 5, p. 564, doi. 10.1111/nan.12048

By:

Brana, Corinne;
Frossard, Marie José;
Pescini Gobert, Rosanna;
Martinier, Nicolas;
Boschert, Ursula;
Seabrook, Timothy J.

Publication type:

Article

Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression.

Published in:

Oncogene, 2014, v. 33, n. 27, p. 3583, doi. 10.1038/onc.2013.319

By:

Kim, E-S;
Cha, Y;
Ham, M;
Jung, J;
Kim, S G;
Hwang, S;
Kleemann, R;
Moon, A

Publication type:

Article

Sphingosine kinase 1 enables communication between melanoma cells and fibroblasts that provides a new link to metastasis.

Published in:

Oncogene, 2014, v. 33, n. 26, p. 3361, doi. 10.1038/onc.2013.292

By:

Pyne, N J;
Pyne, S

Publication type:

Article

Sphingosine 1-phosphate attenuates peroxide-induced apoptosis in HaCaT cells cultured in vitro.

Published in:

Clinical & Experimental Dermatology, 2013, v. 38, n. 6, p. 638, doi. 10.1111/ced.12037

By:

Moriue, T.;
Igarashi, J.;
Yoneda, K.;
Hashimoto, T.;
Nakai, K.;
Kosaka, H.;
Kubota, Y.

Publication type:

Article

Correction to: Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis.

Published in:

2021

By:

Pérez-Jeldres, Tamara;
Alvarez-Lobos, Manuel;
Rivera-Nieves, Jesús

Publication type:

Correction Notice

Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis.

Published in:

Drugs, 2021, v. 81, n. 9, p. 985, doi. 10.1007/s40265-021-01528-8

By:

Pérez-Jeldres, Tamara;
Alvarez-Lobos, Manuel;
Rivera-Nieves, Jesús

Publication type:

Article

Sphingosine 1-phosphate Receptor Modulator Therapy for Multiple Sclerosis: Differential Downstream Receptor Signalling and Clinical Profile Effects.

Published in:

Drugs, 2021, v. 81, n. 2, p. 207, doi. 10.1007/s40265-020-01431-8

By:

Chun, Jerold;
Giovannoni, Gavin;
Hunter, Samuel F.

Publication type:

Article

Apolipoprotein M--A Marker or an Active Player in Type II Diabetes?

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.665393

By:

Christoffersen, Christina

Publication type:

Article

Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction.

Published in:

Virulence, 2013, v. 4, n. 6, p. 572, doi. 10.4161/viru.25740

By:

Darwish, Ilyse;
Liles, W Conrad

Publication type:

Article

N -Acetylcysteine Alleviates Impaired Muscular Function Resulting from Sphingosine Phosphate Lyase Functional Deficiency-Induced Sphingoid Base and Ceramide Accumulation in Caenorhabditis elegans.

Published in:

Nutrients, 2024, v. 16, n. 11, p. 1623, doi. 10.3390/nu16111623

By:

Liu, Min;
You, Yunfei;
Zhu, Huaiyi;
Chen, Yu;
Hu, Zhenying;
Duan, Jingjing

Publication type:

Article

How Does CBG Administration Affect Sphingolipid Deposition in the Liver of Insulin-Resistant Rats?

Published in:

Nutrients, 2023, v. 15, n. 20, p. 4350, doi. 10.3390/nu15204350

By:

Bzdęga, Wiktor;
Kurzyna, Piotr Franciszek;
Harasim-Symbor, Ewa;
Hołownia, Adam;
Chabowski, Adrian;
Konstantynowicz-Nowicka, Karolina

Publication type:

Article

Emerging role of sphingosine-I-phosphate signaling in head and neck squamous cell carcinoma.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 3269, doi. 10.2147/OTT.S99989

By:

Nema, Rajeev;
Vishwakarma, Supriya;
Agarwal, Rahul;
Panday, Rajendra Kumar;
Kumar, Ashok

Publication type:

Article

Sphingosine kinase and sphingosine-1-phosphate regulate epithelial cell architecture by the modulation of de novo sphingolipid synthesis.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0213917

By:

Santacreu, Bruno Jaime;
Pescio, Lucila Gisele;
Romero, Daniela Judith;
Corradi, Gerardo Raúl;
Sterin-Speziale, Norma;
Favale, Nicolás Octavio

Publication type:

Article

Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0209050

By:

Matsushima-Nishiwaki, Rie;
Yamada, Noriko;
Fukuchi, Kouki;
Kozawa, Osamu

Publication type:

Article

Inhibition of autophagy and chemokine induction by sphingosine 1-phosphate receptor 1 through NF-κB signaling in human pulmonary endothelial cells infected with influenza A viruses.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0205344

By:

Wang, Lan;
Jiang, Hao;
Shen, Si-mei;
Wen, Chun-xia;
Xing, Zheng;
Shi, Yi

Publication type:

Article

Activation of the Gi protein-RHOA axis by non-canonical Hedgehog signaling is independent of primary cilia.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0203170

By:

Ho Wei, Lan;
Arastoo, Mohammad;
Georgiou, Ioanna;
Manning, David R.;
Riobo-Del Galdo, Natalia A.

Publication type:

Article

STAT3 expression is a prognostic marker in upper urinary tract urothelial carcinoma.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201256

By:

Matsuzaki, Kyosuke;
Fujita, Kazutoshi;
Hayashi, Yujiro;
Matsushita, Makoto;
Nojima, Satoshi;
Jingushi, Kentaro;
Kato, Taigo;
Kawashima, Atsunari;
Ujike, Takeshi;
Nagahara, Akira;
Uemura, Motohide;
Imamura, Ryoichi;
Yamaguchi, Seiji;
Fushimi, Hiroaki;
Miyamoto, Hiroshi;
Morii, Eiichi;
Nonomura, Norio

Publication type:

Article

Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197401

By:

Riento, Kirsi;
Zhang, Qifeng;
Clark, Jonathan;
Begum, Farida;
Stephens, Elaine;
Wakelam, Michael J.;
Nichols, Benjamin J.

Publication type:

Article

Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197604

By:

Zhao, Juanjuan;
Okamoto, Yasuo;
Asano, Yuya;
Ishimaru, Kazuhiro;
Aki, Sho;
Yoshioka, Kazuaki;
Takuwa, Noriko;
Wada, Takashi;
Inagaki, Yutaka;
Takahashi, Chiaki;
Nishiuchi, Takumi;
Takuwa, Yoh

Publication type:

Article

First evidence of SGPL1 expression in the cell membrane silencing the extracellular S1P siren in mammary epithelial cells.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0196854

By:

Engel, Nadja;
Adamus, Anna;
Frank, Marcus;
Kraft, Karin;
Kühn, Juliane;
Müller, Petra;
Nebe, Barbara;
Kasten, Annika;
Seitz, Guido

Publication type:

Article