Works matching DE "SPHINGOSINE-1-phosphate"

Results: 852

Sphingosine-1-Phosphate Receptor 2 Promotes Renal Microvascular Constriction and Kidney Injury Following Renal Ischemia-Reperfusion in Rats Open Access.

Published in:

Function, 2025, v. 6, n. 3, p. 1, doi. 10.1093/function/zqaf024

By:

Guan, Zhengrong;
Remedies, Colton E;
Zhang, Yanfeng;
Sanders, Paul W;
Inscho, Edward W;
Feng, Wenguang

Publication type:

Article

Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling.

Published in:

Journal of Physiology, 2025, v. 603, n. 15, p. 4329, doi. 10.1113/JP286665

By:

Kostritskaia, Yulia;
Pervaiz, Sumaira;
Klemmer, Anna;
Klüssendorf, Malte;
Stauber, Tobias

Publication type:

Article

Sphingosine-1-phosphate alleviates colitis by regulating macrophage polarization and PI3k-Akt signaling.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1622094

By:

Hu, Liang;
Yang, Zi;
Zhang, Ying;
Du, Conglin;
Yang, Yang;
Chang, Zhichao;
Li, Xiangchun;
Shan, Zhaochen

Publication type:

Article

Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2016, v. 13, n. 5, p. 653, doi. 10.3109/15412555.2016.1153614

By:

Barnawi, Jameel;
Tran, Hai B.;
Roscioli, Eugene;
Hodge, Greg;
Jersmann, Hubertus;
Haberberger, Rainer;
Hodge, Sandra

Publication type:

Article

Genotype/Phenotype Interactions and First Steps Toward Targeted Therapy for Sphingosine Phosphate Lyase Insufficiency Syndrome.

Published in:

Cell Biochemistry & Biophysics, 2021, v. 79, n. 3, p. 547, doi. 10.1007/s12013-021-01013-9

By:

Saba, Julie D.;
Keller, Nancy;
Wang, Jen-Yeu;
Tang, Felicia;
Slavin, Avi;
Shen, Yizhuo

Publication type:

Article

Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells.

Published in:

Cell Biochemistry & Biophysics, 2021, v. 79, n. 3, p. 575, doi. 10.1007/s12013-021-01005-9

By:

Ebenezer, David L.;
Ramchandran, Ramaswamy;
Fu, Panfeng;
Mangio, Lizar A.;
Suryadevara, Vidyani;
Ha, Alison W.;
Berdyshev, Evgeny;
Van Veldhoven, Paul P.;
Kron, Stephen J.;
Schumacher, Fabian;
Kleuser, Burkhard;
Natarajan, Viswanathan

Publication type:

Article

Protective Effect of FTY720 Against Sevoflurane-Induced Developmental Neurotoxicity in Rats.

Published in:

Cell Biochemistry & Biophysics, 2013, v. 67, n. 2, p. 591, doi. 10.1007/s12013-013-9546-3

By:

Zhou, Hui;
Li, Song;
Niu, Xinhuan;
Wang, Ping;
Wang, Junnan;
Zhang, Mengyuan

Publication type:

Article

Interplay Between SAFE and RISK Pathways in Sphingosine-1-Phosphate-Induced Cardioprotection.

Published in:

Cardiovascular Drugs & Therapy, 2012, v. 26, n. 3, p. 227, doi. 10.1007/s10557-012-6376-2

By:

Somers, Sarin;
Frias, Miguel;
Lacerda, Lydia;
Opie, Lionel;
Lecour, Sandrine

Publication type:

Article

Etoposide Upregulates Survival Favoring Sphingosine-1-Phosphate in Etoposide-Resistant Retinoblastoma Cells.

Published in:

Pathology & Oncology Research, 2019, v. 25, n. 1, p. 391, doi. 10.1007/s12253-017-0360-x

By:

Kakkassery, Vinodh;
Skosyrski, S.;
Lüth, A.;
Kleuser, B.;
van der Giet, M.;
Tate, R.;
Reinhard, J.;
Faissner, A.;
Joachim, S. C.;
Kociok, N.

Publication type:

Article

Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K+ Current and Intermediate-Conductance Ca2+-Activated K+ Channel in Jurkat T-Lymphocytes.

Published in:

Molecules, 2020, v. 25, n. 19, p. 4525, doi. 10.3390/molecules25194525

By:

Chang, Wei-Ting;
Liu, Ping-Yen;
Wu, Sheng-Nan

Publication type:

Article

Sphingosine-1-Phosphate Improves the Biological Features of Mouse Bone Marrow-Derived EPCs Partially through PI3K/AKT/eNOS/NO Pathway.

Published in:

Molecules, 2019, v. 24, n. 13, p. 2404, doi. 10.3390/molecules24132404

By:

Wang, Xia;
Zhan, Enxin;
Lu, Guohua;
Mu, Qingjie;
Zhang, Tianliang;
Yang, Nana

Publication type:

Article

Sphingolipidomic Profiling of Rat Serum by UPLC-Q-TOF-MS: Application to Rheumatoid Arthritis Study.

Published in:

Molecules, 2018, v. 23, n. 6, p. 1324, doi. 10.3390/molecules23061324

By:

Qu, Fanghui;
Zhang, Hongyang;
Zhang, Min;
Hu, Ping

Publication type:

Article

Sphingosine 1-Phosphate Receptor 1 Signaling in Mammalian Cells.

Published in:

Molecules, 2017, v. 22, n. 3, p. 344, doi. 10.3390/molecules22030344

By:

Pyne, Nigel J.;
Pyne, Susan

Publication type:

Article

Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients.

Published in:

Archives of Dermatological Research, 2017, v. 309, n. 2, p. 79, doi. 10.1007/s00403-016-1709-9

By:

Myśliwiec, Hanna;
Baran, Anna;
Harasim-Symbor, Ewa;
Choromańska, Barbara;
Myśliwiec, Piotr;
Milewska, Anna;
Chabowski, Adrian;
Flisiak, Iwona

Publication type:

Article

Phytosphingosine-1-phosphate represses the hydrogen peroxide-induced activation of c-Jun N-terminal kinase in human dermal fibroblasts through the phosphatidylinositol 3-kinase/Akt pathway.

Published in:

Archives of Dermatological Research, 2012, v. 304, n. 8, p. 673, doi. 10.1007/s00403-012-1241-5

By:

Lee, Jeong;
Cha, Hwa;
Lee, Kwang;
Lee, Kun;
Son, Ju;
Kim, Kwang;
Lee, Dong;
An, Sungkwan

Publication type:

Article

Galectin-1 Promotes Metastasis in Gastric Cancer Through a Sphingosine-1-Phosphate Receptor 1-Dependent Mechanism.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 51, n. 1, p. 11, doi. 10.1159/000495157

By:

You, Xiaolan;
Wang, Yuanjie;
Wu, Jian;
Liu, Qinghong;
Chen, Dehu;
Tang, Dong;
Wang, Daorong

Publication type:

Article

The Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis in Intestinal Epithelial Cells Regulates Intestinal Barrier Function During Intestinal Epithelial Cells–CD4+T-Cell Interactions.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 48, n. 3, p. 1188, doi. 10.1159/000491985

By:

Chen, Tanzhou;
Lin, Ruoyang;
Jin, Sisi;
Chen, Renpin;
Xue, Haibo;
Ye, Huajun;
Huang, Zhiming

Publication type:

Article

Arteriovenous Sphingosine-1-Phosphate Differences Across Selected Organs of the Rat.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 45, n. 1, p. 67, doi. 10.1159/000486223

By:

Książek, Monika;
Baranowska, Urszula;
Chabowski, Adrian;
Baranowski, Marcin

Publication type:

Article

Differential Regulation of Lung Endothelial Permeability in Vitro and in Situ.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 1, doi. 10.1159/000362980

By:

Uhlig, Stefan;
Yang, Yang;
Waade, Josephine;
Wittenberg, Claudia;
Babendreyer, aaron;
Kuebler, Wolfgang M.

Publication type:

Article

Title Page / Table of Contents.

Published in:: Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. I, doi. 10.1159/000365371
Publication type:: Article

Sphingosine-1-Phosphate Modulates Dendritic Cell Function: Focus on Non-Migratory Effects in Vitro and in Vivo.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 27, doi. 10.1159/000362982

By:

arlt, Olga;
Schwiebs, anja;
Japtok, Lukasz;
Rüger, Katja;
Katzy, Elisabeth;
Kleuser, Burkhard;
Radeke, Heinfried H.

Publication type:

Article

Sphingolipids: Important Players in Multiple Sclerosis.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 111, doi. 10.1159/000362988

By:

Halmer, Ramona;
Walter, Silke;
Faßbender, Klaus

Publication type:

Article

Ceramide Kinase Contributes to Proliferation but not to Prostaglandin E2 Formation in Renal Mesangial Cells and Fibroblasts.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 119, doi. 10.1159/000362989

By:

Pastukhov, Oleksandr;
Schwalm, Stephanie;
Römer, Isolde;
Zangemeister-Wittke, Uwe;
Pfeilschifter, Josef;
Huwiler, andrea

Publication type:

Article

Sphingosine 1-Phosphate in Blood: Function, Metabolism, and Fate.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 158, doi. 10.1159/000362992

By:

Thuy, Andreas V.;
Reimann, Christina-Maria;
Hemdan, Nasr Y. A.;
Gräler, Markus H.

Publication type:

Article

HDL-Bound Sphingosine 1-Phosphate (S1P) Predicts the Severity of Coronary Artery Atherosclerosis.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 172, doi. 10.1159/000362993

By:

Sattler, Katherine;
Lehmann, Isa;
Gräler, Markus;
Bröcker-Preuss, Martina;
Erbel, Raimund;
Heusch, Gerd;
Levkau, Bodo

Publication type:

Article

Sphingosine 1-Phosphate as a Link between Blood Coagulation and Inflammation.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 185, doi. 10.1159/000362994

By:

Rauch, Bernhard Hermann

Publication type:

Article

Divergent Role of Sphingosine 1-Phosphate on Insulin Resistance.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 134, doi. 10.1159/000362990

By:

Fayyaz, Susann;
Japtok, Lukasz;
Kleuser, Burkhard

Publication type:

Article

Sphingosine-1-Phosphate: Boon and Bane for the Brain.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 148, doi. 10.1159/000362991

By:

van Echten-Deckert, Gerhild;
Hagen-Euteneuer, Nadine;
Karaca, Ilker;
Walter, Jochen

Publication type:

Article

Small Molecule Inhibitors of Ceramidases.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 197, doi. 10.1159/000362995

By:

Saied, Essa M.;
arenz, Christoph

Publication type:

Article

Sphingosine 1-Phosphate in Renal Diseases.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2013, v. 31, n. 6, p. 745, doi. 10.1159/000350093

By:

Koch, alexander;
Pfeilschifter, Josef;
Huwiler, andrea

Publication type:

Article

Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2016, v. 21, n. 1/2, p. 9, doi. 10.1007/s10911-016-9354-7

By:

Nagahashi, Masayuki;
Yamada, Akimitsu;
Miyazaki, Hiroshi;
Allegood, Jeremy;
Tsuchida, Junko;
Aoyagi, Tomoyoshi;
Huang, Wei-Ching;
Terracina, Krista;
Adams, Barbara;
Rashid, Omar;
Milstien, Sheldon;
Wakai, Toshifumi;
Spiegel, Sarah;
Takabe, Kazuaki

Publication type:

Article

FOXM1 Enhances Transcription of S1PR1 and Promotes Pro-Inflammatory Activation of Kupffer Cells in Alcoholic Hepatitis.

Published in:

Immunological Investigations, 2025, v. 54, n. 6, p. 824, doi. 10.1080/08820139.2025.2503167

By:

Lu, Ping;
Sun, Tianfeng

Publication type:

Article

The role of sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) in regulation of osteoclastic and osteoblastic cells.

Published in:

Immunological Investigations, 2013, v. 42, n. 7, p. 510, doi. 10.3109/08820139.2013.823804

By:

Dziak, Rosemary

Publication type:

Article

Upregulated Sphingosine 1-Phosphate Receptor 1 Expression in Human and Murine Atherosclerotic Plaques.

Published in:

2018

By:

Liu, Hui;
Jin, Hongjun;
Han, Junbin;
Yue, Xuyi;
Yang, Hao;
Zayed, Mohamed A.;
Gropler, Robert J.;
Tu, Zhude

Publication type:

journal article

PET Imaging Study of S1PR1 Expression in a Rat Model of Multiple Sclerosis.

Published in:

2016

By:

Liu, Hui;
Jin, Hongjun;
Yue, Xuyi;
Luo, Zonghua;
Liu, Chunling;
Rosenberg, Adam;
Tu, Zhude;
Rosenberg, Adam J

Publication type:

journal article

Role of Acid Sphingomyelinase and Ceramide in Mechano-Acoustic Enhancement of Tumor Radiation Responses.

Published in:

2018

By:

Kaffas, Ahmed El;
Al-Mahrouki, Azza;
Hashim, Amr;
Law, Niki;
Giles, Anoja;
Czarnota, Gregory J;
El Kaffas, Ahmed

Publication type:

journal article

DEVELOPMENT OF NEW CYCLOPHILIN D RECEPTOR INHIBITORS FOR THE TREATMENT OF MULTIPLE SCLEROSIS.

Published in:

Journal of Faculty of Pharmacy of Ankara University / Ankara Üniversitesi Eczacilik Fakültesi Dergisi, 2022, v. 46, n. 2, p. 458, doi. 10.33483/jfpau.1090546

By:

YALCIN OZKAT, Gözde;
HUYLU, Birsen

Publication type:

Article

Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment.

Published in:

Scientific Reports, 2015, p. 12017, doi. 10.1038/srep12017

By:

Checa, Antonio;
Sar, Daniel G.;
Haeggström, Jesper Z.;
Wheelock, Craig E.;
Xu, Ning;
Ståhle, Mona

Publication type:

Article

Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05051

By:

Sheridan, Graham K.;
Dev, Kumlesh K.

Publication type:

Article

Sphingosine-1-phosphate Treatment Improves Cryopreservation Efficiency in Human Mesenchymal Stem Cells.

Published in:

Life (2075-1729), 2023, v. 13, n. 6, p. 1286, doi. 10.3390/life13061286

By:

Oh, Seong-Ju;
Jo, Chan-Hee;
Kim, Tae-Seok;
Hong, Chae-Yeon;
Lee, Sung-Lim;
Kang, Young-Hoon;
Rho, Gyu-Jin

Publication type:

Article

Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines.

Published in:

Life (2075-1729), 2021, v. 11, n. 8, p. 851, doi. 10.3390/life11080851

By:

Furuya, Kishio;
Hirata, Hiroaki;
Kobayashi, Takeshi;
Sokabe, Masahiro

Publication type:

Article

Icanbelimod (CBP-307), a next-generation Sphingosine-1-phosphate receptor modulator, in healthy men: pharmacokinetics, pharmacodynamics, safety, and tolerability in a randomized trial in Australia.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1380975

By:

Lickliter, Jason;
Xin Yang;
Jiawang Guo;
Wubin Pan;
Zheng Wei

Publication type:

Article

Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction.

Published in:

Transfusion Medicine, 2016, v. 26, n. 5, p. 365, doi. 10.1111/tme.12326

By:

Nagura, Y.;
Tsuno, N. H.;
Kano, K.;
Inoue, A.;
Aoki, J.;
Hirowatari, Y.;
Kaneko, M.;
Kurano, M.;
Matsuhashi, M.;
Ohkawa, R.;
Tozuka, M.;
Yatomi, Y.;
Okazaki, H.

Publication type:

Article

Alteration of sphingosine‐1‐phosphate with aging induces contractile dysfunction of colonic smooth muscle cells via Ca2+‐activated K+ channel (BKCa) upregulation.

Published in:

Neurogastroenterology & Motility, 2021, v. 33, n. 5, p. 1, doi. 10.1111/nmo.14052

By:

Shen, Xiaoxue;
Zhang, Ling;
Jiang, Ling;
Xiong, Wenjie;
Tang, Yurong;
Lin, Lin;
Yu, Ting

Publication type:

Article

Sphingosine 1-Phosphate Receptor 4 Expression in Colorectal Cancer Patients.

Published in:

Walailak Journal of Science & Technology, 2017, v. 14, n. 8, p. 663

By:

SAMUHASANEETO, Suchittra;
PROMAGSORN, Suthiporn;
PUNSAWAD, Chuchard

Publication type:

Article

A Review of the Role of Sphingosine-1-Phosphate in the Brain: An Important Mediator Implicated in the Central Nervous System.

Published in:

Walailak Journal of Science & Technology, 2014, v. 11, n. 5-8, p. 395

By:

PUNSAWAD, Chuchard

Publication type:

Article

Etrasimod: First Approval.

Published in:

Drugs, 2024, v. 84, n. 2, p. 247, doi. 10.1007/s40265-024-01997-7

By:

Shirley, Matt

Publication type:

Article

Ozanimod: A Review in Ulcerative Colitis.

Published in:

Drugs, 2022, v. 82, n. 12, p. 1303, doi. 10.1007/s40265-022-01762-8

By:

Paik, Julia

Publication type:

Article

Correction to: Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis.

Published in:

2021

By:

Pérez-Jeldres, Tamara;
Alvarez-Lobos, Manuel;
Rivera-Nieves, Jesús

Publication type:

Correction Notice

Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis.

Published in:

Drugs, 2021, v. 81, n. 9, p. 985, doi. 10.1007/s40265-021-01528-8

By:

Pérez-Jeldres, Tamara;
Alvarez-Lobos, Manuel;
Rivera-Nieves, Jesús

Publication type:

Article