Works matching DE "SPHINGOSINE kinase"

Results: 390

Adiponectin mediated metabolic and sphingolipid alterations in preventing endothelial dysfunction.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 7, p. 4365, doi. 10.1007/s11010-025-05268-1

By:

Vincent, Vinnyfred;
Thakkar, Himani;
Sen, Atanu;
Bansal, Ashutosh;
Das, Ujjalkumar Subhash;
Gunasekaran, Abishek;
Bhatla, Neerja;
Velpandian, Thirumurthy;
Singh, Archna

Publication type:

Article

Sphingosine-1-phosphate stimulates colorectal cancer tumor microenvironment angiogenesis and induces macrophage polarization via macrophage migration inhibitory factor.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1564213

By:

Wu, Fang;
Feng, Zhaode;
Wang, Xuan;
Guo, Yingcong;
Wu, Bingcong;
Bai, Shuheng;
Lan, Ning;
Chen, Min;
Ren, Juan

Publication type:

Article

Sphingosine-1-phosphate/sphingosine kinase 1-dependent lymph node metastasis in esophageal squamous cell carcinoma.

Published in:

Surgery Today, 2017, v. 47, n. 11, p. 1312, doi. 10.1007/s00595-017-1514-x

By:

Kawakita, Yuta;
Motoyama, Satoru;
Sato, Yusuke;
Koyota, Souichi;
Wakita, Akiyuki;
Liu, Jiajia;
Saito, Hajime;
Minamiya, Yoshihiro

Publication type:

Article

Isoflurane cerebral preconditioning in a spontaneous hypertension rat model is associated with sphingosine kinases.

Published in:

Advances in Clinical & Experimental Medicine, 2020, v. 29, n. 6, p. 695, doi. 10.17219/acem/121944

By:

Jun Ge;
Keyu Kong;
Xiaoqiang Cheng;
Tianyi Wu;
Dingge Liu;
Lingling Peng;
Zhijia Shen;
Guoyuan Lu;
Yanping Shen

Publication type:

Article

Sphingosine kinase 1 promotes M2 macrophage infiltration and enhances glioma cell migration via the JAK2/STAT3 pathway.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-88328-2

By:

Song, Zihan;
Zhao, Zijun;
Liu, Xuehua;
Song, Yiran;
Zhu, Siyu;
Jia, Ziyang;
Li, Yijie;
Wang, Zairan;
Sun, Boyu;
Jin, Qianxu;
Zhang, Shiyang;
Zhao, Zongmao;
Liu, Liqiang

Publication type:

Article

Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00556

By:

Cannavo, Alessandro;
Liccardo, Daniela;
Komici, Klara;
Corbi, Graziamaria;
de Lucia, Claudio;
Femminella, Grazia D.;
Elia, Andrea;
Bencivenga, Leonardo;
Ferrara, Nicola;
Koch, Walter J.;
Paolocci, Nazareno;
Rengo, Giuseppe

Publication type:

Article

Roles of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor 2 in Endotoxin-Induced Acute Retinal Inflammation.

Published in:

Ocular Immunology & Inflammation, 2024, v. 32, n. 8, p. 1633, doi. 10.1080/09273948.2023.2273963

By:

Ahmed, Tazbir;
Suzuki, Takafumi;
Terao, Ryo;
Yamagishi, Reiko;
Fujino, Ryosuke;
Azuma, Kunihiro;
Soga, Hirotsugu;
Ueta, Takashi;
Honjo, Megumi;
Watanabe, Sumiko;
Yoshioka, Kazuaki;
Takuwa, Yoh;
Aihara, Makoto

Publication type:

Article

Retracted: The Expression and Clinical Significance of Sphingosine Kinase 1 and Vascular Endothelial Growth Factor in Endometrial Carcinoma.

Published in:

2024

By:

International, Emergency Medicine

Publication type:

Correction Notice

The Expression and Clinical Significance of Sphingosine Kinase 1 and Vascular Endothelial Growth Factor in Endometrial Carcinoma.

Published in:

Emergency Medicine International, 2022, p. 1, doi. 10.1155/2022/6716143

By:

Yu, Hong;
Dejizhuoga;
Huang, Wei;
Wang, Donglian;
Gamaquzhen;
Jia, Xiaomin;
Feng, Hao

Publication type:

Article

Exosomal SphK1 from colorectal cancer cells promotes cancer cell migration and activates hepatic stellate cells.

Published in:

Molecular Medicine Reports, 2025, v. 31, n. 3, p. N.PAG, doi. 10.3892/mmr.2025.13438

By:

Zhang, Wenlu;
Xu, Chunyan

Publication type:

Article

Notoginsenoside R1 ameliorates the inflammation induced by amyloid‑β by suppressing SphK1‑mediated NF‑κB activation in PC12 cells.

Published in:

Molecular Medicine Reports, 2024, v. 29, n. 1, p. N.PAG, doi. 10.3892/mmr.2023.13139

By:

Wang, Xiaonan;
Li, Bei;
Yu, Xiaohong;
Zhou, Ye;
Wang, Kaile;
Gao, Yue

Publication type:

Article

Differentially expressed genes on the growth of mouse Leydig cells treated with standardised Eurycoma longifolia extract.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 5, p. 3645

By:

Ahmed, Nor Amira Khurshid;
Lim, Shern Kwok;
Pandian, Ganesh N.;
Sugiyama, Hiroshi;
Lee, Chong Yew;
Khoo, Boon Yin;
Chan, Kit Lam

Publication type:

Article

Inhibition of sphingosine kinase 2 attenuates hypertrophic scar formation via upregulation of Smad7 in human hypertrophic scar fibroblasts.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 3, p. 2573, doi. 10.3892/mmr.2020.11313

By:

Zeng, Jian;
Jiang, Bin;
Xiao, Xia;
Zhang, Rou

Publication type:

Article

Sphingosine kinase 1 contributes to doxorubicin resistance and glycolysis in osteosarcoma.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 3, p. 2183, doi. 10.3892/mmr.2020.11295

By:

Ren, Xiaojun;
Su, Chunhong

Publication type:

Article

MicroRNA‑125b regulates Alzheimer's disease through SphK1 regulation.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 2373, doi. 10.3892/mmr.2018.9156

By:

Jin, Yan;
Tu, Qiuyun;
Liu, Min

Publication type:

Article

Effect of the Interaction between Viral PB2 and Host SphK1 on H9N2 AIV Replication in Mammals.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/v14071585

By:

Zhou, Yong;
Gao, Weihua;
Sun, Yan;
Guo, Yuxin;
Wu, Yuping;
Pu, Juan

Publication type:

Article

A Novel Sphingosine Kinase Inhibitor Suppresses Chikungunya Virus Infection.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 6, p. N.PAG, doi. 10.3390/v14061123

By:

Oyewole, Opeoluwa O.;
Dunnavant, Kyle;
Bhattarai, Shaurav;
Kharel, Yugesh;
Lynch, Kevin R.;
Santos, Webster L.;
Reid, St. Patrick

Publication type:

Article

Chronic LCMV Infection Is Fortified with Versatile Tactics to Suppress Host T Cell Immunity and Establish Viral Persistence.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 10, p. 1951, doi. 10.3390/v13101951

By:

Studstill, Caleb J.;
Hahm, Bumsuk

Publication type:

Article

Emerging Connections of S1P-Metabolizing Enzymes with Host Defense and Immunity During Virus Infections.

Published in:

Viruses (1999-4915), 2019, v. 11, n. 12, p. 1097, doi. 10.3390/v11121097

By:

Wolf, Jennifer J.;
Studstill, Caleb J.;
Hahm, Bumsuk

Publication type:

Article

Evaluation of the lymphocyte trafficking drug FTY720 in vaginal tissues.

Published in:

Journal of Medical Primatology, 2013, v. 42, n. 2, p. 89, doi. 10.1111/jmp.12033

By:

Tsuiki, Ai;
Luo, Wei;
Henning, Tara;
Vishwanathan, Sundaram;
Dinh, Chuong;
Adams, Debra;
Sweeney, Elizabeth;
Mitchell, James;
Bachman, Shannon;
Sharma, Prachi;
Powell, Nathaniel;
Hendry, Michael;
McNicholl, Janet;
Kersh, Ellen

Publication type:

Article

Involvement of vacuolar H+- ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.

Published in:

Pigment Cell & Melanoma Research, 2015, v. 28, n. 2, p. 171, doi. 10.1111/pcmr.12326

By:

Tay, Kwang Hong;
Liu, Xiaoying;
Chi, Mengna;
Jin, Lei;
Jiang, Chen Chen;
Guo, Su Tang;
Verrills, Nicole M.;
Tseng, Hsin ‐ Yi;
Zhang, Xu Dong

Publication type:

Article

Targeting sphingosine kinase-1 to inhibit melanoma.

Published in:

Pigment Cell & Melanoma Research, 2012, v. 25, n. 2, p. 259, doi. 10.1111/j.1755-148X.2012.00970.x

By:

Madhunapantula, SubbaRao V.;
Hengst, Jeremy;
Gowda, Raghavendra;
Fox, Todd E.;
Yun, Jong K.;
Robertson, Gavin P.

Publication type:

Article

Gene expression profiling of the masticatory muscle tendons and Achilles tendons under tensile strain in the Japanese macaque Macaca fuscata.

Published in:

PLoS ONE, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pone.0280649

By:

Ito, Ko;
Go, Yasuhiro;
Tatsumoto, Shoji;
Usui, Chika;
Mizuno, Yosuke;
Ikami, Eiji;
Isozaki, Yuta;
Usui, Michihiko;
Kajihara, Takeshi;
Yoda, Tetsuya;
Inoue, Ken-ichi;
Takada, Masahiko;
Sato, Tsuyoshi

Publication type:

Article

Role of sphingosine kinase and sphingosine-1-phosphate receptor in the liver pathology of mice infected with Plasmodium berghei ANKA.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0266055

By:

Techarang, Tachpon;
Jariyapong, Pitchanee;
Punsawad, Chuchard

Publication type:

Article

miR-153-3p Attenuates the Development of Gastric Cancer by Suppressing SphK2.

Published in:

Biochemical Genetics, 2022, v. 60, n. 5, p. 1748, doi. 10.1007/s10528-021-10166-4

By:

Jia, Zhengwo;
Tang, Xiaofang;
Zhang, Xicheng;
Shen, Jingen;
Sun, Yuanlong;
Qian, Lifen

Publication type:

Article

Blocking SphK1/S1P/S1PR1 Signaling Pathway Alleviates Lung Injury Caused by Sepsis in Acute Ethanol Intoxication Mice.

Published in:

Inflammation, 2021, v. 44, n. 6, p. 2170, doi. 10.1007/s10753-021-01490-3

By:

Chen, Liang;
Li, Lingling;
Song, Yong;
Lv, Tangfeng

Publication type:

Article

SPHK-2 Promotes the Particle-Induced Inflammation of RAW264.7 by Maintaining Consistent Expression of TNF-α and IL-6.

Published in:

Inflammation, 2018, v. 41, n. 4, p. 1498, doi. 10.1007/s10753-018-0795-6

By:

Yang, Guangpu;
Gu, Minghui;
Chen, Weishen;
Liu, Wenhua;
Xiao, Yinbo;
Wang, Haixing;
Lai, Weiming;
Xian, Guoyan;
Zhang, Ziji;
Li, Ziqing;
Sheng, Puyi

Publication type:

Article

A2 B Adenosine Receptors and Sphingosine 1-Phosphate Signaling Cross-Talk in Oligodendrogliogenesis.

Published in:

Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.677988

By:

Coppi, Elisabetta;
Cencetti, Francesca;
Cherchi, Federica;
Venturini, Martina;
Donati, Chiara;
Bruni, Paola;
Pedata, Felicita;
Pugliese, Anna Maria

Publication type:

Article

Co-administration phenoxodiol with doxorubicin synergistically inhibit the activity of sphingosine kinase-1 (SphK1), a potential oncogene of osteosarcoma, to suppress osteosarcoma cell growth both in vivo and in vitro

Published in:

Molecular Oncology, 2012, v. 6, n. 4, p. 392, doi. 10.1016/j.molonc.2012.04.002

By:

Yao, Chen;
Wu, Sujia;
Li, Dong;
Ding, Huimin;
Wang, Zuyu;
Yang, Yongjiang;
Yan, Shichang;
Gu, Zhangping

Publication type:

Article

Significance of sphingosine kinase 1 expression in feline mammary tumors.

Published in:

BMC Veterinary Research, 2019, v. 15, n. 1, p. 1, doi. 10.1186/s12917-019-1883-z

By:

Chang, Yi-Chih;
Chuang, Hsiao-Li;
Yin, Ji-Hang;
Liao, Jiunn-Wang;
Chen, Ter-Hsin;
Wang, Yu-Chih

Publication type:

Article

Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/8606878

By:

Aoki, Masayo;
Aoki, Hiroaki;
Ramanathan, Rajesh;
Hait, Nitai C.;
Takabe, Kazuaki

Publication type:

Article

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 48, p. 9645, doi. 10.1523/JNEUROSCI.0524-19.2019

By:

Lei, Mona;
Teo, Jonathan D.;
Huitong Song;
McEwen, Holly P.;
Jun Yup Lee;
Couttas, Timothy A.;
Duncan, Thomas;
Chesworth, Rose;
Bertz, Josefine;
Przybyla, Magdalena;
Van Eersel, Janet;
Heng, Benjamin;
Guillemin, Gilles J.;
Ittner, Lars M.;
Fath, Thomas;
Garner, Brett;
Ittner, Arne;
Karl, Tim;
Don, Anthony S.

Publication type:

Article

Sphingosine Kinase Regulates Neuropeptide Secretion During the Oxidative Stress-Response Through Intertissue Signaling.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 38, p. 8160, doi. 10.1523/JNEUROSCI.0536-18.2018

By:

Sungjin Kim;
Sieburth, Derek

Publication type:

Article

Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor negative breast cancer.

Published in:

British Journal of Cancer, 2012, v. 107, n. 4, p. 756, doi. 10.1038/bjc.2012.352

By:

Ohotski, J;
Long, J S;
Orange, C;
Elsberger, B;
Mallon, E;
Doughty, J;
Pyne, S;
Pyne, N J;
Edwards, J

Publication type:

Article

Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer.

Published in:

British Journal of Cancer, 2012, v. 106, n. 8, p. 1453, doi. 10.1038/bjc.2012.98

By:

Ohotski, J;
Long, J S;
Orange, C;
Elsberger, B;
Mallon, E;
Doughty, J;
Pyne, S;
Pyne, N J;
Edwards, J

Publication type:

Article

Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection.

Published in:

British Journal of Cancer, 2012, v. 106, n. 5, p. 909, doi. 10.1038/bjc.2012.14

By:

Nunes, J;
Naymark, M;
Sauer, L;
Muhammad, A;
Keun, H;
Sturge, J;
Stebbing, J;
Waxman, J;
Pchejetski, D

Publication type:

Article

An Unanticipated Role for Sphingosine Kinase-2 in Bone and in the Anabolic Effect of Parathyroid Hormone.

Published in:

Endocrinology, 2021, v. 162, n. 5, p. 1, doi. 10.1210/endocr/bqab042

By:

Walker, Joanne M;
Yao, Gang-Qing;
Siu, Edwin;
Zhu, Meiling;
Sun, Ben-hua;
Simpson, Christine;
Insogna, Karl L

Publication type:

Article

Metabolic Adaptation of Airway Smooth Muscle Cells to an SPHK2 Substrate Precedes Cytostasis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2020, v. 62, n. 1, p. 35, doi. 10.1165/rcmb.2018-0397OC

By:

Blais-Lecours, Pascale;
Laouafa, Sofien;
Arias-Reyes, Christian;
Santos, Webster L.;
Joseph, Vincent;
Burgess, Janette K.;
Halayko, Andrew J.;
Soliz, Jorge;
Marsolais, David

Publication type:

Article

Insulin-like growth factor receptor and sphingosine kinase are prognostic and therapeutic targets in breast cancer.

Published in:

2017

By:

Ochnik, Aleksandra M.;
Baxter, Robert C.

Publication type:

journal article

Enzymatic independent role of sphingosine kinase 2 in regulating the expression of type I interferon during influenza A virus infection.

Published in:

PLoS Pathogens, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.ppat.1010794

By:

Xu, Mengqiong;
Xia, Sisi;
Wang, Mei;
Liu, Xiaolian;
Li, Xin;
Chen, Weijie;
Wang, Yaohao;
Li, Hongjian;
Xia, Chuan;
Chen, Jun;
Wu, Jianguo

Publication type:

Article

High-density lipoprotein induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through sphingosine kinase-2.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 389, n. 1/2, p. 197, doi. 10.1007/s11010-013-1941-y

By:

Xiong, Sheng-Lin;
Liu, Xing;
Yi, Guang-Hui

Publication type:

Article

Intracellular Sphingosine-1-Phosphate Receptor 3 Contributes to Lung Tumor Cell Proliferation.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2021, v. 55, n. 5, p. 539, doi. 10.33594/000000431

By:

Terlizzi, Michela;
Colarusso, Chiara;
Ferraro, Giusy;
Monti, Maria Chiara;
De Rosa, Ilaria;
Somma, Pasquale;
Salvi, Rosario;
Pinto, Aldo;
Sorrentino, Rosalinda

Publication type:

Article

Bone marrow mesenchymal stem cells‐derived exosomes reduce Aβ deposition and improve cognitive function recovery in mice with Alzheimer's disease by activating sphingosine kinase/sphingosine‐1‐phosphate signaling pathway.

Published in:

Cell Biology International, 2021, v. 45, n. 4, p. 775, doi. 10.1002/cbin.11522

By:

Wang, Xinhui;
Yang, Guojie

Publication type:

Article

The Role of Sphingolipid Metabolism in Pregnancy-Associated Breast Cancer After Chemotherapy.

Published in:

Biomedicines, 2024, v. 12, n. 12, p. 2843, doi. 10.3390/biomedicines12122843

By:

Blokhin, Victor;
Zavarykina, Tatiana;
Kotsuba, Vasily;
Kapralova, Maria;
Gutner, Uliana;
Shupik, Maria;
Kozyrko, Elena;
Luzina, Evgenia;
Lomskova, Polina;
Bajgazieva, Darya;
Khokhlova, Svetlana;
Alessenko, Alice

Publication type:

Article

Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras.

Published in:

Experimental & Therapeutic Medicine, 2019, v. 18, n. 4, p. 2401, doi. 10.3892/etm.2019.7753

By:

Nachreiner, Inga;
Hussain, Ahmad Fawzi;
Wullner, Ulrich;
Machuy, Nikolaus;
Meyer, Thomas F.;
Fischer, Rainer;
Gattenlöhner, Stefan;
Meinhold-Heerlein, Ivo;
Barth, Stefan;
Tur, Mehmet Kemal

Publication type:

Article

Sphingosine kinase 1 overexpression is associated with poor prognosis and oxaliplatin resistance in hepatocellular carcinoma.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 6, p. 5371, doi. 10.3892/etm.2018.6086

By:

Wang, Fangping;
Wu, Zhiming

Publication type:

Article

SPHK1 promotes metastasis of thyroid carcinoma through activation of the S1P/S1PR3/Notch signaling pathway.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 6, p. 5007, doi. 10.3892/etm.2018.6054

By:

Zhao, Zhijing;
Ma, Junfeng;
Hu, Baoquan;
Zhang, Yi;
Wang, Shushu

Publication type:

Article

SphK1‐driven autophagy potentiates focal adhesion paxillin‐mediated metastasis in colorectal cancer.

Published in:

Cancer Medicine, 2021, v. 10, n. 17, p. 6010, doi. 10.1002/cam4.4129

By:

Wu, Jiang‐Ni;
Lin, Lan;
Luo, Shi‐Bo;
Qiu, Xin‐Ze;
Zhu, Li‐Ye;
Chen, Da;
Wei, Er‐Dan;
Fu, Zhen‐Hua;
Qin, Meng‐Bin;
Liang, Zhi‐Hai;
Huang, Jie‐An;
Liu, Shi‐Quan

Publication type:

Article

SPHK1‐induced autophagy in peritoneal mesothelial cell enhances gastric cancer peritoneal dissemination.

Published in:

Cancer Medicine, 2019, v. 8, n. 4, p. 1731, doi. 10.1002/cam4.2041

By:

Yin, Songcheng;
Miao, Zhifeng;
Tan, Yuen;
Wang, Pengliang;
Xu, Xiaoyu;
Zhang, Chao;
Hou, Wenbin;
Huang, Jinyu;
Xu, Huimian

Publication type:

Article

Survival benefit of sphingosin‐1‐phosphate and receptors expressions in breast cancer patients.

Published in:

Cancer Medicine, 2018, v. 7, n. 8, p. 3743, doi. 10.1002/cam4.1609

By:

Lei, Fu‐Ju;
Liao, Pei‐Yin;
Chang, Wei‐Chun;
Ma, Wen‐Lung;
Wang, Hsiao‐Ching;
Lai, Hsueh‐Chou;
Yang, Juan‐Cheng;
Cheng, Bi‐Hua;
Chu, Li‐Ching;
Wu, Yang‐Chang

Publication type:

Article