Works matching DE "SPHINGOMYELINASE"

Results: 334

SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06829-0

By:

Rostami-Afshari, Bita;
Elremaly, Wesam;
Franco, Anita;
Elbakry, Mohamed;
Akoume, Marie-Yvonne;
Boufaied, Ines;
Moezzi, Atefeh;
Leveau, Corinne;
Rompré, Pierre;
Godbout, Christian;
Mella, Olav;
Fluge, Øystein;
Moreau, Alain

Publication type:

Article

Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2018, v. 37, n. 5, p. 1395, doi. 10.1007/s10067-017-3824-1

By:

Hanaoka, Beatriz Y.;
Ormseth, Michelle J.;
Michael Stein, C.;
Banerjee, Daipayan;
Nikolova-Karakashian, Mariana;
Crofford, Leslie J.

Publication type:

Article

Secretory Acid Sphingomyelinase in the Serum of Medicated Patients Predicts the Prospective Course of Depression.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 6, p. 846, doi. 10.3390/jcm8060846

By:

Mühle, Christiane;
Wagner, Claudia Johanna;
Färber, Katharina;
Richter-Schmidinger, Tanja;
Gulbins, Erich;
Lenz, Bernd;
Kornhuber, Johannes

Publication type:

Article

Elevated Serum Levels of Acid Sphingomyelinase in Female Patients with Episodic and Chronic Migraine.

Published in:

Antioxidants, 2025, v. 14, n. 2, p. 159, doi. 10.3390/antiox14020159

By:

Ouro, Alberto;
Castro-Mosquera, Mónica;
Rodríguez-Arrizabalaga, Mariña;
Debasa-Mouce, Manuel;
Custodia, Antía;
Aramburu-Núñez, Marta;
Romaus-Sanjurjo, Daniel;
Casas, Josefina;
Lema, Isabel;
Castillo, José;
Leira, Rogelio;
Sobrino, Tomás

Publication type:

Article

Accelerated Sarcopenia Phenotype in the DJ-1/ Park7 -Knockout Zebrafish.

Published in:

Antioxidants, 2024, v. 13, n. 12, p. 1509, doi. 10.3390/antiox13121509

By:

Rostad, Kristine O.;
Trognitz, Tobias;
Frøyset, Ann Kristin;
Bifulco, Ersilia;
Fladmark, Kari E.

Publication type:

Article

Chronic acid sphingomyelinase deficiency diagnosed in infancy/childhood in Polish patients: 2024 update.

Published in:

Advances in Clinical & Experimental Medicine, 2024, v. 33, n. 10, p. 1163, doi. 10.17219/acem/193696

By:

Lipiński, Patryk;
Ługowska, Agnieszka;
Tylki-Szymańska, Anna

Publication type:

Article

Pulmonary Involvement in Niemann-Pick Disease: A State-of-the-Art Review.

Published in:

Lung (0341-2040), 2016, v. 194, n. 4, p. 511, doi. 10.1007/s00408-016-9893-0

By:

Ranke, Felipe;
Pereira Freitas, Heloisa;
Mançano, Alexandre;
Rodrigues, Rosana;
Hochhegger, Bruno;
Escuissato, Dante;
Araujo Neto, Cesar;
Silva, Thiago;
Marchiori, Edson

Publication type:

Article

Role of Inositol Phosphosphingolipid Phospholipase C1, the Yeast Homolog of Neutral Sphingomyelinases in DNA Damage Response and Diseases.

Published in:

Journal of Lipids, 2015, v. 2015, p. 1, doi. 10.1155/2015/161392

By:

Tripathi, Kaushlendra

Publication type:

Article

Correction: Probiotic Sonicates Selectively Induce Mucosal Immune Cells Apoptosis through Ceramide Generation via Neutral Sphingomyelinase.

Published in:: 2022
Publication type:: Correction Notice

Regulation of NLRP3 Inflammasome Activation and Inflammatory Exosome Release in Podocytes by Acid Sphingomyelinase During Obesity.

Published in:

Inflammation, 2023, v. 46, n. 5, p. 2037, doi. 10.1007/s10753-023-01861-y

By:

Huang, Dandan;
Kidd, Jason M.;
Zou, Yao;
Wu, Xiaoyuan;
Gehr, Todd W. B.;
Li, Pin-Lan;
Li, Guangbi

Publication type:

Article

Acid Sphingomyelinase and Acid β-Glucosidase 1 Exert Opposite Effects on Interleukin-1β-Induced Interleukin 6 Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.

Published in:

Inflammation, 2021, v. 44, n. 4, p. 1592, doi. 10.1007/s10753-021-01444-9

By:

Zhao, Mengmeng;
Yang, Maowei;
Li, Xu;
Hou, Linxin;
Liu, Xudong;
Xiao, Weiguo

Publication type:

Article

Determination of acid sphingomyelinase activity in biological samples with ultra-performance liquid chromatographic assay.

Published in:

Journal of Liquid Chromatography & Related Technologies, 2018, v. 41, n. 13/14, p. 855, doi. 10.1080/10826076.2018.1531021

By:

Luo, Lei;
Li, Na;
Li, Jimeng;
Sun, Biancheng;
Huang, Ting;
Zeng, Ming;
Xiao, Fang

Publication type:

Article

Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 33, p. 8653, doi. 10.1523/JNEUROSCI.1429-16.2016

By:

Dinkins, Michael B.;
Enasko, John;
Hernandez, Caterina;
Guanghu Wang;
Jina Kong;
Helwa, Inas;
Yutao Liu;
Terry Jr., Alvin V.;
Bieberich, Erhard

Publication type:

Article

Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 5, p. 629, doi. 10.1165/rcmb.2020-0229OC

By:

Poczobutt, Joanna M.;
Mikosz, Andrew M.;
Poirier, Christophe;
Beatman, Erica L.;
Serban, Karina A.;
Gally, Fabienne;
Cao, Danting;
McCubbrey, Alexandra L.;
Cornell, Christina F.;
Schweitzer, Kelly S.;
Berdyshev, Evgeny V.;
Bronova, Irina A.;
Paris, François;
Petrache, Irina

Publication type:

Article

Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency: ONLINE DATA SUPPLEMENT.

Published in:: American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 5, p. E1, doi. 10.1165/rcmb.2020-0229oc
Publication type:: Article

Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis.

Published in:

Cardiovascular Diabetology, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12933-023-01747-1

By:

Liu, Ruijiao;
Duan, Tengfei;
Yu, Li;
Tang, Yongzhong;
Liu, Shikun;
Wang, Chunjiang;
Fang, Wei-Jin

Publication type:

Article

Rücktitelbild: Single‐Molecule 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes (Angew. Chem. 40/2020).

Published in:

Angewandte Chemie, 2020, v. 132, n. 40, p. 17912, doi. 10.1002/ange.202011444

By:

Lu, Jin;
Mazidi, Hesam;
Ding, Tianben;
Zhang, Oumeng;
Lew, Matthew D.

Publication type:

Article

Role of ErbB and IL-1 signaling pathways in the dermonecrotic lesion induced by Loxosceles sphingomyelinases D.

Published in:

Archives of Toxicology, 2023, v. 97, n. 12, p. 3285, doi. 10.1007/s00204-023-03602-4

By:

Pinto, Bruna Fernandes;
Lopes, Priscila Hess;
Trufen, Carlos Eduardo Madureira;
Ching, Ana Tung Ching;
De Azevedo, Inácio de Loiola Meirelles Junqueira;
Nishiyama Jr, Milton Yutaka;
Pohl, Paula Cristiane;
Tambourgi, Denise V.

Publication type:

Article

The relevance of acid sphingomyelinase as a potential target for therapeutic intervention in hepatic disorders: current scenario and anticipated trends.

Published in:

Archives of Toxicology, 2023, v. 97, n. 8, p. 2069, doi. 10.1007/s00204-023-03529-w

By:

Mir, Ishfaq Hassan;
Thirunavukkarasu, Chinnasamy

Publication type:

Article

ASMase is Essential for the Immune Response to Partial-Tumor Radiation Exposure.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2024, v. 58, n. 5, p. 477, doi. 10.33594/000000726

By:

Mathieu, Mickael;
Nepali, Prerna R.;
Russell, James;
Askarifirouzjaei, Hadi;
Baltaci, Melis;
Powell, Simon N.;
Humm, John;
Deasy, Joseph O.;
Haimovitz-Friedman, Adriana

Publication type:

Article

Acid Sphingomyelinase-Ceramide System in Bacterial Infections.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 2, p. 280, doi. 10.33594/000000021

By:

Cao Li;
Anni Wang;
Yuqing Wu;
Gulbins, Erich;
Grassmé, Heike;
Zhigang Zhao

Publication type:

Article

SMPDL3B contributes to gastric adenocarcinoma cells progression by promoting the infiltration of M2 macrophages.

Published in:

Turkish Journal of Medical Sciences, 2023, v. 53, n. 6, p. 1635, doi. 10.55730/1300-0144.5732

By:

Li SU;
Jian HAO;
Na ZHANG;
Shan WU;
Xiuhua WU;
Wei WEI

Publication type:

Article

Acid Sphingomyelinase and Ceramide Signaling Pathway Mediates Nicotine-Induced NLRP3 Inflammasome Activation and Podocyte Injury.

Published in:

Biomedicines, 2025, v. 13, n. 2, p. 416, doi. 10.3390/biomedicines13020416

By:

Rahman, Mohammad Atiqur;
Datta, Sayantap;
Lakkakula, Harini;
Koka, Saisudha;
Boini, Krishna M.

Publication type:

Article

Utilizing Sphingomyelinase Sensitizing Liposomes in Imaging Intestinal Inflammation in Dextran Sulfate Sodium-Induced Murine Colitis.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 413, doi. 10.3390/biomedicines10020413

By:

Penate Medina, Tuula;
Pan, Jie;
Damoah, Christabel;
Humbert, Jana;
Köpnick, Anna-Lena;
Will, Olga;
Sebens, Susanne;
Penate Medina, Oula

Publication type:

Article

Changes in the Sphingolipid Content in Tissues and Behavioral Modifications of Rats Subjected to Neurogenic Stress: Role of Sphingomyelinases.

Published in:

Neurophysiology, 2016, v. 48, n. 6, p. 390, doi. 10.1007/s11062-017-9615-0

By:

Babenko, N.;
Shevereva, V.;
Gar'kavenko, V.

Publication type:

Article

Effect of an Inhibitor of Sphingomyelinases, N-Acetylcysteine, on Cognitive Functions in Old Rats.

Published in:

Neurophysiology, 2014, v. 46, n. 2, p. 180, doi. 10.1007/s11062-014-9426-5

By:

Babenko, N.;
Shakhova, O.

Publication type:

Article

Microparticles in sickle cell disease.

Published in:

Clinical Hemorheology & Microcirculation, 2018, v. 68, n. 2-3, p. 319, doi. 10.3233/CH-189014

By:

Romana, Marc;
Connes, Philippe;
Key, Nigel S.;
Connes

Publication type:

Article

Construction of a lipid metabolism‐related and immune‐associated prognostic signature for hepatocellular carcinoma.

Published in:

Cancer Medicine, 2020, v. 9, n. 20, p. 7646, doi. 10.1002/cam4.3353

By:

Hu, Bo;
Yang, Xiao‐Bo;
Sang, Xin‐Ting

Publication type:

Article

Imipramine, an Acid Sphingomyelinase Inhibitor, Promotes Newborn Neuron Survival in the Hippocampus After Seizure.

Published in:

Cells (2073-4409), 2025, v. 14, n. 4, p. 281, doi. 10.3390/cells14040281

By:

Lee, Song Hee;
Yang, Hyun Wook;
Kang, Beom Seok;
Park, Min Kyu;
Kim, Dong Yeon;
Song, Hong Ki;
Choi, Hui Chul;
Lee, Minwoo;
Choi, Bo Young;
Son, Dae-Soon;
Suh, Sang Won

Publication type:

Article

Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation.

Published in:

Cells (2073-4409), 2024, v. 13, n. 5, p. 463, doi. 10.3390/cells13050463

By:

Al-Rashed, Fatema;
Arefanian, Hossein;
Madhoun, Ashraf Al;
Bahman, Fatemah;
Sindhu, Sardar;
AlSaeed, Halemah;
Jacob, Texy;
Thomas, Reeby;
Al-Roub, Areej;
Alzaid, Fawaz;
Malik, MD Zubbair;
Nizam, Rasheeba;
Thanaraj, Thangavel Alphonse;
Al-Mulla, Fahd;
Hannun, Yusuf A.;
Ahmad, Rasheed

Publication type:

Article

Proximity Ligation Mapping of Microcephaly Associated SMPD4 Shows Association with Components of the Nuclear Pore Membrane.

Published in:

Cells (2073-4409), 2022, v. 11, n. 4, p. 674, doi. 10.3390/cells11040674

By:

Piët, Alexandra C. A.;
Post, Marco;
Dekkers, Dick;
Demmers, Jeroen A. A.;
Fornerod, Maarten

Publication type:

Article

Administration of an Acidic Sphingomyelinase (ASMase) Inhibitor, Imipramine, Reduces Hypoglycemia-Induced Hippocampal Neuronal Death.

Published in:

Cells (2073-4409), 2022, v. 11, n. 4, p. 667, doi. 10.3390/cells11040667

By:

Kho, A Ra;
Choi, Bo Young;
Lee, Song Hee;
Hong, Dae Ki;
Kang, Beom Seok;
Lee, Si Hyun;
Suh, Sang Won

Publication type:

Article

Acid Sphingomyelinase Controls Early Phases of Skeletal Muscle Regeneration by Shaping the Macrophage Phenotype.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 3028, doi. 10.3390/cells10113028

By:

Roux-Biejat, Paulina;
Coazzoli, Marco;
Marrazzo, Pasquale;
Zecchini, Silvia;
Di Renzo, Ilaria;
Prata, Cecilia;
Napoli, Alessandra;
Moscheni, Claudia;
Giovarelli, Matteo;
Barbalace, Maria Cristina;
Catalani, Elisabetta;
Bassi, Maria Teresa;
De Palma, Clara;
Cervia, Davide;
Malaguti, Marco;
Hrelia, Silvana;
Clementi, Emilio;
Perrotta, Cristiana

Publication type:

Article

Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems.

Published in:

Cells (2073-4409), 2020, v. 9, n. 11, p. 2502, doi. 10.3390/cells9112502

By:

Zeitler, Stefanie;
Schumacher, Fabian;
Monti, Juliana;
Anni, Daniela;
Guhathakurta, Debarpan;
Kleuser, Burkhard;
Friedland, Kristina;
Fejtová, Anna;
Kornhuber, Johannes;
Rhein, Cosima

Publication type:

Article

Acid Sphingomyelinase Contributes to the Control of Mycobacterial Infection via a Signaling Cascade Leading from Reactive Oxygen Species to Cathepsin D.

Published in:

Cells (2073-4409), 2020, v. 9, n. 11, p. 2406, doi. 10.3390/cells9112406

By:

Wu, Yuqing;
Li, Cao;
Peng, Huiming;
Swaidan, Ashraf;
Riehle, Andrea;
Pollmeier, Barbara;
Zhang, Yang;
Gulbins, Erich;
Grassmé, Heike

Publication type:

Article

The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice.

Published in:

Cells (2073-4409), 2020, v. 9, n. 5, p. 1244, doi. 10.3390/cells9051244

By:

Zoicas, Iulia;
Schumacher, Fabian;
Kleuser, Burkhard;
Reichel, Martin;
Gulbins, Erich;
Fejtova, Anna;
Kornhuber, Johannes;
Rhein, Cosima

Publication type:

Article

Acid Sphingomyelinase Downregulation Enhances Mitochondrial Fusion and Promotes Oxidative Metabolism in a Mouse Model of Melanoma.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 848, doi. 10.3390/cells9040848

By:

Coazzoli, Marco;
Napoli, Alessandra;
Roux-Biejat, Paulina;
De Palma, Clara;
Moscheni, Claudia;
Catalani, Elisabetta;
Zecchini, Silvia;
Conte, Vincenzo;
Giovarelli, Matteo;
Caccia, Sonia;
Procacci, Patrizia;
Cervia, Davide;
Clementi, Emilio;
Perrotta, Cristiana

Publication type:

Article

Systemic lupus erythematosus occurring in a patient with Niemann–Pick type B disease.

Published in:

2015

By:

Murgia, G.;
Firinu, D.;
Meleddu, R.;
Lorrai, M. M.;
Manconi, P. E.;
del Giacco, S. R.

Publication type:

Case Study

Membrane Progesterone Receptors: Evidence for Neuroprotective, Neurosteroid Signaling and Neuroendocrine Functions in Neuronal Cells.

Published in:

Neuroendocrinology, 2012, v. 96, n. 2, p. 162, doi. 10.1159/000339822

By:

Thomas, Peter;
Pang, Yefei

Publication type:

Article

Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs.

Published in:

Pharmaceutics, 2025, v. 17, n. 1, p. 20, doi. 10.3390/pharmaceutics17010020

By:

Ranjit, Arina;
Lee, Chae Bin;
Tenora, Lukáš;
Mettu, Vijaya Saradhi;
Pal, Arindom;
Alt, Jesse;
Slusher, Barbara S.;
Rais, Rana

Publication type:

Article

Medications Modulating the Acid Sphingomyelinase/Ceramide System and 28-Day Mortality among Patients with SARS-CoV-2: An Observational Study.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 8, p. 1107, doi. 10.3390/ph16081107

By:

Hoertel, Nicolas;
Rezaei, Katayoun;
Sánchez-Rico, Marina;
Delgado-Álvarez, Alfonso;
Kornhuber, Johannes;
Gulbins, Erich;
Olfson, Mark;
Ouazana-Vedrines, Charles;
Carpinteiro, Alexander;
Cougoule, Céline;
Becker, Katrin Anne;
Alvarado, Jesús M.;
Limosin, Frédéric

Publication type:

Article

Update on Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) in SARS-CoV-2 Infection.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 7, p. 691, doi. 10.3390/ph14070691

By:

Loas, Gwenolé;
Le Corre, Pascal

Publication type:

Article

Association between Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) and Reduced Risk of Death in COVID-19 Patients: A Retrospective Cohort Study.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 3, p. 226, doi. 10.3390/ph14030226

By:

Darquennes, Gil;
Le Corre, Pascal;
Le Moine, Olivier;
Loas, Gwenolé;
Vanden Eynde, Jean Jacques

Publication type:

Article

Venom of the Brazilian Spider Sicarius ornatus (Araneae, Sicariidae) Contains Active Sphingomyelinase D: Potential for Toxicity after Envenomation.

Published in:

2013

By:

Lopes, Priscila Hess;
Bertani, Rogério;
Gonçalves-de-Andrade, Rute M.;
Nagahama, Roberto H.;
van den Berg, Carmen W.;
Tambourgi, Denise V.

Publication type:

Case Study

Venom of the Brazilian Spider <i>Sicarius ornatus</i> (Araneae, Sicariidae) Contains Active Sphingomyelinase D: Potential for Toxicity after Envenomation.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 8, p. 1, doi. 10.1371/journal.pntd.0002394

By:

Lopes, Priscila Hess;
Bertani, Rogério;
Gonçalves-de-Andrade, Rute M.;
Nagahama, Roberto H.;
van den Berg, Carmen W.;
Tambourgi, Denise V.

Publication type:

Article

Inhibition of acid sphingomyelinase by imipramine abolishes the synergy between metabolic syndrome and periodontitis on alveolar bone loss.

Published in:

Journal of Periodontal Research, 2022, v. 57, n. 1, p. 173, doi. 10.1111/jre.12951

By:

Li, Yanchun;
Lu, Zhongyang;
Zhang, Lixia;
Kirkwood, Cameron L.;
Kirkwood, Keith L.;
Lopes‐Virella, Maria F.;
Huang, Yan

Publication type:

Article

Inhibition of acid sphingomyelinase by imipramine abolishes the synergy between metabolic syndrome and periodontitis on alveolar bone loss.

Published in:

Journal of Periodontal Research, 2022, v. 57, n. 1, p. 173, doi. 10.1111/jre.12951

By:

Li, Yanchun;
Lu, Zhongyang;
Zhang, Lixia;
Kirkwood, Cameron L.;
Kirkwood, Keith L.;
Lopes‐Virella, Maria F.;
Huang, Yan

Publication type:

Article

Identification of seven novel SMPD1 mutations causing Niemann-Pick disease types A and B.

Published in:

Clinical Genetics, 2013, v. 84, n. 4, p. 356, doi. 10.1111/cge.12076

By:

Irun, P;
Mallén, M;
Dominguez, C;
Rodriguez‐Sureda, V;
Alvarez‐Sala, LA;
Arslan, N;
Bermejo, N;
Guerrero, C;
Perez de Soto, I;
Villalón, L;
Giraldo, P;
Pocovi, M

Publication type:

Article

Acid sphingomyelinase modulates anxiety-like behavior likely through toll-like receptor signaling pathway.

Published in:

Molecular Brain, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13041-025-01178-x

By:

Yuan, Huiqi;
Xu, Yanan;
Jiang, Hailun;
Jiang, Meizhu;
Zhang, Luofei;
Wei, Shifeng;
Li, Cao;
Zhao, Zhigang

Publication type:

Article

Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr<sup>-/-</sup> mice fed on a high-fat diet.

Published in:

Bioscience Reports, 2012, v. 32, n. 5, p. 479, doi. 10.1042/BSR20120036

By:

DEEVSKA, Gergana M.;
SUNKARA, Manjula;
MORRIS, Andrew J.;
NIKOLOVA-KARAKASHIAN, Mariana N.

Publication type:

Article