Works matching DE "SODIUM channel inhibition"

Results: 32

Ranolazine Treatment for Myocardial Infarction? Effects on the Development of Necrosis, Left Ventricular Function and Arrhythmias in Experimental Models.

Published in:

Cardiovascular Drugs & Therapy, 2014, v. 28, n. 5, p. 469, doi. 10.1007/s10557-014-6548-3

By:

Hale, Sharon;
Kloner, Robert

Publication type:

Article

Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91528-1

By:

Ton, Anh Tuan;
Nguyen, William;
Sweat, Katrina;
Miron, Yannick;
Hernandez, Eduardo;
Wong, Tiara;
Geft, Valentyna;
Macias, Andrew;
Espinoza, Ana;
Truong, Ky;
Rasoul, Lana;
Stafford, Alexa;
Cotta, Tamara;
Mai, Christina;
Indersmitten, Tim;
Page, Guy;
Miller, Paul E.;
Ghetti, Andre;
Abi-Gerges, Najah

Publication type:

Article

Magnolol inhibits sodium currents in freshly isolated mouse dorsal root ganglion neurons.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 3, p. 347, doi. 10.1111/1440-1681.13422

By:

Qiu, Jie;
Zhang, Lulu;
Hong, Jiangru;
Ni, Xiao;
Li, Jun;
Li, Guang;
Zhang, Guangqin

Publication type:

Article

Cellular mechanisms for trazodone-induced cardiotoxicity.

Published in:

Human & Experimental Toxicology, 2016, v. 35, n. 5, p. 501, doi. 10.1177/0960327115595683

By:

Lee, S.;
Lee, H-A;
Kim, S. J.;
Kim, K-S

Publication type:

Article

Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00012

By:

Hou, Yapeng;
Cui, Yong;
Zhou, Zhiyu;
Liu, Hongfei;
Zhang, Honglei;
Ding, Yan;
Nie, Hongguang;
Ji, Hong-Long

Publication type:

Article

Ranolazine improves autonomic balance in heart failure when added to guideline-driven therapy.

Published in:

Heart International, 2014, v. 9, n. 2, p. 59, doi. 10.5301/heartint.5000215

By:

Murray, Gary L.;
Colombo, Joseph

Publication type:

Article

Continuous monitoring of plant sodium transport dynamics using clinical PET.

Published in:

Plant Methods, 2021, v. 17, n. 1, p. 1, doi. 10.1186/s13007-021-00707-8

By:

Ruwanpathirana, Gihan P.;
Plett, Darren C.;
Williams, Robert C.;
Davey, Catherine E.;
Johnston, Leigh A.;
Kronzucker, Herbert J.

Publication type:

Article

Urokinase‐type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)‐mediated sodium retention in experimental nephrotic syndrome.

Published in:

Acta Physiologica, 2019, v. 227, n. 4, p. N.PAG, doi. 10.1111/apha.13286

By:

Bohnert, Bernhard N.;
Daiminger, Sophie;
Wörn, Matthias;
Sure, Florian;
Staudner, Tobias;
Ilyaskin, Alexandr V.;
Batbouta, Firas;
Janessa, Andrea;
Schneider, Jonas C.;
Essigke, Daniel;
Kanse, Sandip;
Haerteis, Silke;
Korbmacher, Christoph;
Artunc, Ferruh

Publication type:

Article

Proteasuria—The impact of active urinary proteases on sodium retention in nephrotic syndrome.

Published in:

Acta Physiologica, 2019, v. 225, n. 4, p. N.PAG, doi. 10.1111/apha.13249

By:

Wörn, Matthias;
Artunc, Ferruh;
Schork, Anja;
Bohnert, Bernhard N.

Publication type:

Article

Sodium channel haploinsufficiency and structural change in ventricular arrhythmogenesis.

Published in:

Acta Physiologica, 2016, v. 216, n. 2, p. 186, doi. 10.1111/apha.12577

By:

Jeevaratnam, K.;
Guzadhur, L.;
Goh, Y. M.;
Grace, A. A.;
Huang, C. L.‐H.

Publication type:

Article

Function of Inhibitory Micronetworks Is Spared by Na+ Channel-Acting Anticonvulsant Drugs.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 29, p. 9720, doi. 10.1523/JNEUROSCI.2395-13.2014

By:

Pothmann, Leonie;
Müller, Christina;
Averkin, Robert G.;
Bellistri, Elisa;
Miklitz, Carolin;
Uebachs, Mischa;
Remy, Stefan;
de la Prida, Liset Menendez;
Beck, Heinz

Publication type:

Article

ALSUntangled No. 22: Propofol.

Published in:: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2013, v. 14, n. 7/8, p. 640, doi. 10.3109/21678421.2013.826469
Publication type:: Article

Sodium Channel Inhibitors Reduce DMPK mRNA and Protein.

Published in:

CTS: Clinical & Translational Science, 2015, v. 8, n. 4, p. 298, doi. 10.1111/cts.12275

By:

Witherspoon, Luke;
O'Reilly, Sean;
Hadwen, Jeremiah;
Tasnim, Nafisa;
MacKenzie, Alex;
Farooq, Faraz

Publication type:

Article

Prominent role of forebrain excitatory neurons in SCN8A encephalopathy.

Published in:

2019

By:

Bunton-Stasyshyn, Rosie K A;
Wagnon, Jacy L;
Wengert, Eric R;
Barker, Bryan S;
Faulkner, Alexa;
Wagley, Pravin K;
Bhatia, Kritika;
Jones, Julie M;
Maniaci, Marissa R;
Parent, Jack M;
Goodkin, Howard P;
Patel, Manoj K;
Meisler, Miriam H

Publication type:

journal article

Tetrodotoxin blocks L-type Ca channels in canine ventricular cardiomyocytes.

Published in:

Pflügers Archiv: European Journal of Physiology, 2012, v. 464, n. 2, p. 167, doi. 10.1007/s00424-012-1114-y

By:

Hegyi, Bence;
Bárándi, László;
Komáromi, István;
Papp, Ferenc;
Horváth, Balázs;
Magyar, János;
Bányász, Tamás;
Krasznai, Zoltán;
Szentandrássy, Norbert;
Nánási, Péter

Publication type:

Article

Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 inmurine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.

Published in:

Cardiovascular Research, 2017, v. 113, n. 7, p. 829, doi. 10.1093/cvr/cvx077

By:

Portero, Vincent;
Casini, Simona;
Hoekstra, Maaike;
Verkerk, Arie O.;
Mengarelli, Isabella;
Belardinelli, Luiz;
Rajamani, Sridharan;
Wilde, Arthur A. M.;
Bezzina, Connie R.;
Veldkamp, Marieke W.;
Remme, Carol Ann

Publication type:

Article

Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension.

Published in:

Cardiovascular Research, 2014, v. 104, n. 1, p. 37, doi. 10.1093/cvr/cvu188

By:

Rocchetti, Marcella;
Sala, Luca;
Rizzetto, Riccardo;
Staszewsky, Lidia Irene;
Alemanni, Matteo;
Zambelli, Vanessa;
Russo, Ilaria;
Barile, Lucio;
Cornaghi, Laura;
Altomare, Claudia;
Ronchi, Carlotta;
Mostacciuolo, Gaspare;
Lucchetti, Jacopo;
Gobbi, Marco;
Latini, Roberto;
Zaza, Antonio

Publication type:

Article

Intracellular Immunohistochemical Detection of Tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria).

Published in:

Marine Drugs, 2015, v. 13, n. 2, p. 756, doi. 10.3390/md13020756

By:

Salvitti, Lauren R.;
Wood, Susanna A.;
Winsor, Leigh;
Cary, Stephen Craig

Publication type:

Article

Cardiac Late Sodium Channel Current (Late-INa) is a Molecular Target in the Heart for the Sodium/Glucose Cotransporter 2 (SGLT2) Inhibitor Empagliflozin, Contributing to Cardioprotection.

Published in:

Rhythmos, 2021, v. 16, n. 3, p. 68

By:

Manolis, Antonis S.;
Anninos, Hector

Publication type:

Article

Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.

Published in:

2016

By:

Jones, Hannah;
Butt, Richard;
Webster, Rob;
Gurrell, Ian;
Dzygiel, Pawel;
Flanagan, Neil;
Fraier, Daniela;
Hay, Tanya;
Iavarone, Laura;
Luckwell, Jacquelynn;
Pearce, Hannah;
Phipps, Alex;
Segelbacher, Jill;
Speed, Bill;
Beaumont, Kevin;
Jones, Hannah M;
Butt, Richard P;
Webster, Rob W;
Iavarone, Laura Else

Publication type:

journal article

Effect of Topically Applied Epithelial Sodium Channel Inhibitors on Tear Production in Normal Mice and in Mice with Induced Aqueous Tear Deficiency.

Published in:

Journal of Ocular Pharmacology & Therapeutics, 2012, v. 28, n. 4, p. 433, doi. 10.1089/jop.2011.0157

By:

Thelin, William R.;
Johnson, M. Ross;
Hirsh, Andrew J.;
Kublin, Claire L.;
Zoukhri, Driss

Publication type:

Article

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 2, p. 1, doi. 10.3390/ijms21020373

By:

Nattramilarasu, Praveen Kumar;
Bücker, Roland;
Lobo de Sá, Fábia Daniela;
Fromm, Anja;
Nagel, Oliver;
Lee, In-Fah Maria;
Butkevych, Eduard;
Mousavi, Soraya;
Genger, Claudia;
Kløve, Sigri;
Heimesaat, Markus M.;
Bereswill, Stefan;
Schweiger, Michal R.;
Nielsen, Hans Linde;
Troeger, Hanno;
Schulzke, Jörg-Dieter

Publication type:

Article

Identification of putative natriuretic hormones isolated from human urine.

Published in:

Frontiers in Endocrinology, 2015, v. 6, p. 1, doi. 10.3389/fendo.2015.00066

By:

Kramer, Herbert J.

Publication type:

Article

A Single Crossing-Over Event in Voltage-Sensitive Na+ Channel Genes May Cause Critical Failure of Dengue Mosquito Control by Insecticides.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 8, p. 1, doi. 10.1371/journal.pntd.0003085

By:

Hirata, Koichi;
Komagata, Osamu;
Itokawa, Kentaro;
Yamamoto, Atsushi;
Tomita, Takashi;
Kasai, Shinji

Publication type:

Article

Axonal sodium and potassium conductance density determines spiking dynamical properties of regular- and fast-spiking neurons.

Published in:

Nonlinear Dynamics, 2019, v. 95, n. 2, p. 1035, doi. 10.1007/s11071-018-4613-3

By:

Zhang, Wen;
Fan, Boqiang;
Agarwal, Divyansh;
Li, Tun;
Yu, Yuguo

Publication type:

Article

Sodium channel-inhibiting drugs and survival of breast, colon and prostate cancer: a population-based study.

Published in:

Scientific Reports, 2015, p. 16758, doi. 10.1038/srep16758

By:

Watt, Ian;
Martin, Fabiola;
Fairhurst, Caroline;
Bland, Martin;
Brackenbury, William J.

Publication type:

Article

Resveratrol Inhibits the Epithelial Sodium Channel via Phopshoinositides and AMP-Activated Protein Kinase in Kidney Collecting Duct Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078019

By:

Weixel, Kelly M.;
Marciszyn, Allison;
Alzamora, Rodrigo;
Li, Hui;
Fischer, Oliver;
Edinger, Robert S.;
Hallows, Kenneth R.;
Johnson, John P.

Publication type:

Article

Modulation of Mononuclear Phagocyte Inflammatory Response by Liposome-Encapsulated Voltage Gated Sodium Channel Inhibitor Ameliorates Myocardial Ischemia/Reperfusion Injury in Rats.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074390

By:

Zhou, Xin;
Luo, Yue-Chen;
Ji, Wen-Jie;
Zhang, Li;
Dong, Yan;
Ge, Lan;
Lu, Rui-Yi;
Sun, Hai-Ying;
Guo, Zao-Zeng;
Yang, Guo-Hong;
Jiang, Tie-Min;
Li, Yu-Ming

Publication type:

Article

Involvement of the epithelial sodium channel in initiation of mechanically evoked swallows in anaesthetized rats.

Published in:

Journal of Physiology, 2019, v. 597, n. 11, p. 2949, doi. 10.1113/JP277895

By:

Tsujimura, Takanori;
Ueha, Rumi;
Yoshihara, Midori;
Takei, Eri;
Nagoya, Kouta;
Shiraishi, Naru;
Magara, Jin;
Inoue, Makoto

Publication type:

Article

Whole-exome sequencing identifies a novel mutation (R367G) in SCN5A to be associated with familial cardiac conduction disease.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 1, p. 410, doi. 10.3892/mmr.2017.6592

By:

Rong Yu;
Xue-Feng Fan;
Chan Chen;
Zheng-Hua Liu

Publication type:

Article

Liddle-Mutation of the β-Subunit, but not the γ-Subunit, Attenuates Protein Kinase C-Mediated Inhibition of Human Epithelial Sodium Channels (hENaC).

Published in:

2016

By:

Robins, Gerard;
Sandle, Geoffrey;
Robins, Gerard G;
Sandle, Geoffrey I

Publication type:

journal article

Therapeutic Value of Voltage-Gated Sodium Channel Inhibitors in Breast, Colorectal, and Prostate Cancer: A Systematic Review.

Published in:

Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00273

By:

Martin, Fabiola;
Ufodiama, Chiedu;
Watt, Ian;
Bland, Martin;
Brackenbury, William J.;
Roger, Sébastien;
Gillet, Ludovic

Publication type:

Article

Works matching DE "SODIUM channel inhibition"

Ranolazine Treatment for Myocardial Infarction? Effects on the Development of Necrosis, Left Ventricular Function and Arrhythmias in Experimental Models.

Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart.

Magnolol inhibits sodium currents in freshly isolated mouse dorsal root ganglion neurons.

Cellular mechanisms for trazodone-induced cardiotoxicity.

Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection.

Ranolazine improves autonomic balance in heart failure when added to guideline-driven therapy.

Continuous monitoring of plant sodium transport dynamics using clinical PET.

Urokinase‐type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)‐mediated sodium retention in experimental nephrotic syndrome.

Proteasuria—The impact of active urinary proteases on sodium retention in nephrotic syndrome.

Sodium channel haploinsufficiency and structural change in ventricular arrhythmogenesis.

Function of Inhibitory Micronetworks Is Spared by Na<sup>+</sup> Channel-Acting Anticonvulsant Drugs.

ALSUntangled No. 22: Propofol.

Sodium Channel Inhibitors Reduce DMPK mRNA and Protein.

Prominent role of forebrain excitatory neurons in SCN8A encephalopathy.

Tetrodotoxin blocks L-type Ca channels in canine ventricular cardiomyocytes.

Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 inmurine Scn5a-1798insD<sup>+/-</sup> and human SCN5A-1795insD<sup>+/-</sup> iPSC-derived cardiomyocytes.

Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension.

Intracellular Immunohistochemical Detection of Tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria).

Cardiac Late Sodium Channel Current (Late-I<sub>Na</sub>) is a Molecular Target in the Heart for the Sodium/Glucose Cotransporter 2 (SGLT2) Inhibitor Empagliflozin, Contributing to Cardioprotection.

Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels.

Effect of Topically Applied Epithelial Sodium Channel Inhibitors on Tear Production in Normal Mice and in Mice with Induced Aqueous Tear Deficiency.

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption.

Identification of putative natriuretic hormones isolated from human urine.

A Single Crossing-Over Event in Voltage-Sensitive Na<sup>+</sup> Channel Genes May Cause Critical Failure of Dengue Mosquito Control by Insecticides.

Axonal sodium and potassium conductance density determines spiking dynamical properties of regular- and fast-spiking neurons.

Sodium channel-inhibiting drugs and survival of breast, colon and prostate cancer: a population-based study.

Resveratrol Inhibits the Epithelial Sodium Channel via Phopshoinositides and AMP-Activated Protein Kinase in Kidney Collecting Duct Cells.

Modulation of Mononuclear Phagocyte Inflammatory Response by Liposome-Encapsulated Voltage Gated Sodium Channel Inhibitor Ameliorates Myocardial Ischemia/Reperfusion Injury in Rats.

Involvement of the epithelial sodium channel in initiation of mechanically evoked swallows in anaesthetized rats.

Whole-exome sequencing identifies a novel mutation (R367G) in SCN5A to be associated with familial cardiac conduction disease.

Liddle-Mutation of the β-Subunit, but not the γ-Subunit, Attenuates Protein Kinase C-Mediated Inhibition of Human Epithelial Sodium Channels (hENaC).

Therapeutic Value of Voltage-Gated Sodium Channel Inhibitors in Breast, Colorectal, and Prostate Cancer: A Systematic Review.