Works matching DE "SMALL molecules"

Results: 5000

Comprehensive and Updated Algorithm of Hidradenitis Suppurativa Management from the Experts.

Published in:

American Journal of Clinical Dermatology, 2025, v. 26, n. 4, p. 487, doi. 10.1007/s40257-025-00940-0

By:

Dagenet, Caitlyn B.;
Lee, Katrina H.;
Sayed, Christopher;
Hsiao, Jennifer L.;
Shi, Vivian Y.

Publication type:

Article

Investigation of liquid distribution in gas–solid fluidized beds for fluid cokers.

Published in:

Canadian Journal of Chemical Engineering, 2025, v. 103, n. 8, p. 3983, doi. 10.1002/cjce.25596

By:

Cochet, Yohann;
Briens, Cedric;
Berruti, Franco;
McMillan, Jennifer

Publication type:

Article

Effect of Water on Local Structure and Dynamics in a Protic Ionic Liquid‐Based Electrolyte.

Published in:

ChemSusChem, 2025, v. 18, n. 13, p. 1, doi. 10.1002/cssc.202402753

By:

Lundin, Filippa;
Stettner, Timo;
Falus, Peter;
Balducci, Andrea;
Matic, Aleksandar

Publication type:

Article

OrthologAL: a Shiny application for quality-aware humanization of non-human pre-clinical high-dimensional gene expression data Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 6, p. 1, doi. 10.1093/bioinformatics/btaf311

By:

Chowdary, Rishika;
Suter, Robert K;
D'Antuono, Matthew;
Gomes, Cynthia;
Stein, Joshua;
Lee, Ki-Bum;
Lee, Jae K;
Ayad, Nagi G

Publication type:

Article

Current perspectives on Lp(a)-lowering therapies: Who may benefit?

Published in:

Polish Heart Journal / Kardiologia Polska, 2025, v. 83, n. 6, p. 688, doi. 10.33963/v.phj.106327

By:

Nicholls, Stephen J.;
Nelson, Adam J.

Publication type:

Article

RNA G-quadruplexes: emerging regulators of gene expression and therapeutic targets.

Published in:

Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01656-4

By:

Ruzi, Zukela;
Zha, Wei;
Yuan, Huang Yuan;
Liu, Jiaorui

Publication type:

Article

Water Activation by Methyllanthanides: Hydrogen Versus Methane Evolution.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2025, v. 39, n. 15, p. 1, doi. 10.1002/rcm.10054

By:

Wan, Songpeng;
Gong, Yu;
Chen, Xiuting

Publication type:

Article

Intramolecular PCET of α‐Keto Acids: Synthesis of Trifluoromethyl Ketones via Ketyl Radicals.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 37, p. 1, doi. 10.1002/chem.202501613

By:

Nabi, Rifat N.;
Jarquin, Kimberly A.;
Karmakar, Anupam;
Brunner, Kyle E.;
Kim, Daniel K.

Publication type:

Article

Divergent Responses of Carbon Nitride Dot‐Based Amorphous Species and Small Molecule Hybrids to Trace Level Analytes.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 37, p. 1, doi. 10.1002/chem.202501495

By:

Holzmann, Michael J.;
Westphal, Eric R.;
Plackowski, Kenneth M.;
Meyerson, Melissa L.;
Grey, John K.;
Ghosh, Koushik

Publication type:

Article

Spectroscopic Interrogation of Thiolate Hydrogen Bonding in the CO Sensor Protein CooA: Implications for Thiolate Ligation Stability and Cytochrome P450 Function.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 37, p. 1, doi. 10.1002/chem.202404504

By:

Weaver, Brian R.;
Jodts, Richard J.;
Hoffman, Brian M.;
Telser, Joshua;
Burstyn, Judith N.

Publication type:

Article

Impact of Linking‐Site on Photovoltaic Performance of Giant Molecular Acceptors Containing N‐Type Linker.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 27, p. 1, doi. 10.1002/adfm.202423774

By:

Meng, Shixin;
Zang, Yu;
Wang, Zongtao;
Fu, Hongyuan;
Zhang, Ming;
Yao, Jia;
Wang, Qingyuan;
Wang, Haiqiao;
Yi, Yuanping;
Xue, Lingwei;
Zhou, Erjun;
Zhang, Zhi‐Guo

Publication type:

Article

Effect of transforming growth factor beta receptor I inhibitors on myotube formation in vitro.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09381-5

By:

De Saeytyd, Louise;
Wang, Zhihao;
Bloemen, Marjon;
Von den Hoff, Johannes W.

Publication type:

Article

Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128-3p agomir and Oroxin B: A novel drug delivery approach based on PI3K-AKT and VEGF pathway crosstalk.

Published in:

Asian Journal of Pharmaceutical Sciences, 2025, v. 20, n. 3, p. 1, doi. 10.1016/j.ajps.2024.100909

By:

Hechen Wang;
Xudan Shen;
Jiatong Liu;
Xinlan Zhu;
Su Zeng;
Sheng Cai

Publication type:

Article

STK3 is a transcriptional target of YAP1 and a hub component in the crosstalk between Hippo and Wnt signaling pathways during gastric carcinogenesis.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02391-x

By:

Xie, Fuda;
Lyu, Yang;
Chen, Bonan;
Leung, Hoi Wing;
Yu, Peiyao;
Feng, Tiejun;
Fang, Canbin;
Cheung, Alvin H.K.;
Zhou, Bin;
Jiang, Jianhui;
Zhang, Ge;
Xu, Dazhi;
Li, Liang;
Jiang, Chen;
Chen, Jianwu;
Zhou, Zhaocai;
An, Liwei;
Huang, Bing;
Zhuang, Kangmin;
Luo, Xiaobei

Publication type:

Article

SE(3)-equivariant ternary complex prediction towards target protein degradation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61272-5

By:

Xue, Fanglei;
Zhang, Meihan;
Li, Shuqi;
Gao, Xinyu;
Wohlschlegel, James A.;
Huang, Wenbing;
Yang, Yi;
Deng, Weixian

Publication type:

Article

Small-molecule-induced liquid-liquid phase separation suppresses the carcinogenesis of β-catenin.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61112-6

By:

Yan, Jin;
Liu, Heyuan;
Yang, Wenguang;
Liu, Na;
Wang, Jingmei;
Li, Zhanfeng;
Liu, Tianya;
Yan, Siqi;
He, Wangxiao

Publication type:

Article

A small molecule enhances arrestin-3 binding to the β<sub>2</sub>-adrenergic receptor.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01581-4

By:

Kurt, Han;
Akyol, Ali;
Son, Cagdas Devrim;
Zheng, Chen;
Gado, Irene;
Meli, Massimiliano;
Ferrandi, Erica Elisa;
Bassanini, Ivan;
Vasile, Francesca;
Gurevich, Vsevolod V.;
Nebol, Aylin;
Cagavi, Esra;
Morra, Giulia;
Sensoy, Ozge

Publication type:

Article

Denaturation of DNA and Albumin Protein in the Presence of New Antitumor Candidate.

Published in:

Applied Organometallic Chemistry, 2025, v. 39, n. 7, p. 1, doi. 10.1002/aoc.70208

By:

Behroozi, Roghayeh;
Dehghanian, Effat;
Tabatabai, Ashraf Sadat Dorafshan;
Jalali, Mahsa;
Dehghanian, Leila;
Mansouri‐Torshizi, Hassan

Publication type:

Article

A comparative assessment of density functional approximations for inner reorganization energy: insights from small molecules models with varying degrees of charge delocalization.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2025, v. 144, n. 6, p. 1, doi. 10.1007/s00214-025-03187-4

By:

Flores, Raul;
Sánchez-Bojorge, Nora Aydeé;
Palomares-Báez, Juan Pedro;
Landeros-Martínez, Linda-Lucila;
Rodríguez-Valdez, Luz María

Publication type:

Article

Tailoring of Albumin Nanoparticles Modified with Mannose for Effective Targeting in Immunosuppressive Tumor Microenvironment.

Published in:

Micro (2673-8023), 2025, v. 5, n. 2, p. 30, doi. 10.3390/micro5020030

By:

Kuznetsova, Alyona B.;
Gorbacheva, Valentina I.;
Kolesova, Ekaterina P.;
Egorova, Vera S.

Publication type:

Article

Efficient Room-Temperature Luminescence of Indole-5-Carboxamide in Poly(vinyl alcohol) Films.

Published in:

Photochem, 2025, v. 5, n. 2, p. 14, doi. 10.3390/photochem5020014

By:

Lee, Bong;
Jablonska, Agnieszka;
Sagoo, Rajveer;
Pham, Danh;
Pham, Trang Thien;
Dzyuba, Sergei V.;
Gryczynski, Zygmunt;
Gryczynski, Ignacy

Publication type:

Article

Simulating Methylamine Using a Symmetry-Adapted, Qubit Excitation-Based Variational Quantum Eigensolver.

Published in:

Quantum Reports, 2025, v. 7, n. 2, p. 21, doi. 10.3390/quantum7020021

By:

Makushin, Konstantin M.;
Fedorov, Aleksey K.

Publication type:

Article

Structure–activity relationship of <sup>18</sup>F-labeled PD-L1-targeting small molecule ligands: impact of radiolabeling strategy on affinity and in vivo performance.

Published in:

EJNMMI Radiopharmacy & Chemistry, 2025, v. 10, n. 1, p. 1, doi. 10.1186/s41181-025-00359-2

By:

Krutzek, Fabian;
Donat, Cornelius K.;
Stadlbauer, Sven

Publication type:

Article

Self-assembling T7 phage syringes with modular genomes for targeted delivery of penicillin against β-lactam-resistant Escherichia coli.

Published in:

BMC Biotechnology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12896-025-01003-2

By:

Shim, Hyunjin

Publication type:

Article

An Alternative Method for Preparing Methyl 2-Ferrocenyl-2-oxo-acetate.

Published in:

Molbank, 2025, v. 2025, n. 2, p. M2009, doi. 10.3390/M2009

By:

Pigeon, Pascal;
Hapel, Hugo

Publication type:

Article

Role of Small Organic Molecules in Perovskite Light‐Emitting Diodes: Applications, Mechanisms and Prospects.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 26, p. 1, doi. 10.1002/adfm.202500348

By:

Zhang, Feihu;
Guo, Runda;
Zeng, Haibo;
Wang, Lei

Publication type:

Article

Sulfur‐Bridged Pure Organic Ester Clusters Exhibiting Near‐Infrared Fluorescence.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 26, p. 1, doi. 10.1002/adfm.202420830

By:

Liu, Xiong;
Guo, Jiafang;
Xiong, Zuping;
Li, Xiang;
Lv, Yanbing;
Zhang, Ziteng;
Chu, Bo;
Zhang, Haoke;
Sun, Jing Zhi;
Zhang, Xinghong;
Tang, Ben Zhong

Publication type:

Article

Chemically Triggered Dopant Release from Surface-Modified Polypyrrole Films.

Published in:

Surfaces (2571-9637), 2025, v. 8, n. 2, p. 23, doi. 10.3390/surfaces8020023

By:

Richter, Grant;
Knepper, Allen;
Molino, Paul J.;
Hanks, Timothy W.

Publication type:

Article

Generation of Immune Modulating Small Metabolites—Metabokines—By Adult Schistosomes.

Published in:

Pathogens, 2025, v. 14, n. 6, p. 526, doi. 10.3390/pathogens14060526

By:

Skelly, Patrick J.;
Da'dara, Akram A.

Publication type:

Article

A High-Throughput Inhibitor Screen Targeting CLAG3 Export and Membrane Insertion on Human Erythrocytes Infected with Malaria Parasites.

Published in:

Pathogens, 2025, v. 14, n. 6, p. 520, doi. 10.3390/pathogens14060520

By:

Shao, Jinfeng;
Chu, Jonathan;
Mohammad, Kashif;
Desai, Sanjay A.

Publication type:

Article

Correction: Development and validation of an ARID1A-related immune genes risk model in evaluating prognosis and immune therapeutic efficacy for gastric cancer patients: a translational study.

Published in:

2025

By:

Zhang, Jiangtao;
Li, Jingting;
Yang, Shangfeng;
Tang, Xiaoyan;
Wang, Chunze;
Lin, Jiaxing;
Chen, Qiancheng;
Xu, Hui;
Ma, Yuanyuan;
Gao, Xiaoling

Publication type:

Correction Notice

Development and validation of an ARID1A-related immune genes risk model in evaluating prognosis and immune therapeutic efficacy for gastric cancer patients: a translational study.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1541491

By:

Zhang, Jiangtao;
Li, Jingting;
Yang, Shangfeng;
Tang, Xiaoyan;
Wang, Chunze;
Lin, Jiaxing;
Chen, Qiancheng;
Xu, Hui;
Ma, Yuanyuan;
Gao, Xiaoling

Publication type:

Article

Biological properties and genomic analysis of the fourth strain of molliviruses encoding a eukaryotic-like transmembrane transport protein.

Published in:

Virology Journal, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12985-025-02850-3

By:

Xia, Yucheng;
Su, Baiyu;
Ren, Hongwei;
Liu, Feifei;
Cai, Lanlan;
Wong, Yue-Him;
Zhang, Rui

Publication type:

Article

Natural small molecule smart hydrogels inhibited the Hsp90/NF‐κB signaling axis in inflammation to achieve sustained antipyretic effect.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03517-5

By:

Yang, Yuqin;
Jiao, Jingyi;
Jia, Xiaohui;
Li, Lei;
Wu, Meiling;
Lu, Xinyue;
Sun, Yangyang;
Lang, Yingqi;
Chu, Fuhao;
Bai, Dong;
Wang, Penglong;
Lei, Haimin

Publication type:

Article

Biodegradation of Poly(ε-caprolactone): Microorganisms, Enzymes, and Mechanisms.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5826, doi. 10.3390/ijms26125826

By:

Krumov, Nikolay;
Atanasova, Nikolina;
Boyadzhieva, Ivanka;
Petrov, Kaloyan;
Petrova, Penka

Publication type:

Article

New Advances in Anti-HIV-1 Strategies Targeting the Assembly and Stability of Capsid Protein.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5819, doi. 10.3390/ijms26125819

By:

Zhang, Chengfeng;
Li, Benteng;
Li, Jiamei;
Zhang, Haihong;
Wu, Yuqing

Publication type:

Article

Strategies to Develop Na,K-ATPase-α4 Inhibitors as Male Contraceptives.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5646, doi. 10.3390/ijms26125646

By:

Syeda, Shameem S.;
Sánchez, Gladis;
McDermott, Jeffrey P.;
Cheryala, Narsihmulu;
Wong, Henry L.;
Georg, Gunda I.;
Blanco, Gustavo

Publication type:

Article

Discovery of Small Molecules Targeting Norovirus 3CL Protease by Multi-Stage Virtual Screening.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5625, doi. 10.3390/ijms26125625

By:

Shi, Zhongling;
Liu, Na;
Zhao, Fabao;
Kang, Dongwei;
De Jonghe, Steven;
Neyts, Johan;
Gao, Ni;
Liu, Xinyong

Publication type:

Article

Hammerhead Ribozymes: Structural Insights, Catalytic Mechanisms, and Cutting-Edge Applications in Synthetic Biology.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5624, doi. 10.3390/ijms26125624

By:

Wang, Liangliang;
Liu, Yan;
Xian, Xuemin;
Zhang, Haitao

Publication type:

Article

Targeting the p53/xCT/GSH Axis with PRIMA-1 Met Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5559, doi. 10.3390/ijms26125559

By:

Pasino, Martina;
Speciale, Andrea;
Ravera, Silvia;
Cutrona, Giovanna;
Massara, Rosanna;
Bertola, Nadia;
Viale, Maurizio;
Velkova, Irena;
Mazzarello, Andrea Nicola;
Fais, Franco;
Loiacono, Fabrizio;
Matis, Serena;
Valenti, Giulia Elda;
Traverso, Nicola;
Domenicotti, Cinzia;
Marengo, Barbara;
Tasso, Bruno;
Ibatici, Adalberto;
Angelucci, Emanuele;
Vaisitti, Tiziana

Publication type:

Article

SsDiHal: discovery and engineering of a novel tryptophan dihalogenase.

Published in:

Journal of Biological Engineering, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13036-025-00518-8

By:

Sher, Hassan;
Hardtke, Haley;
Tang, Wenzhu;
Ren, Jie;
Ullah, Hayat;
Zhou, Xudong;
Zhang, Y. Jessie;
Zhan, Jixun

Publication type:

Article

Discovery of Small Molecule PD‐L1 Inhibitors via Optimization of Solvent‐Interaction Region for Cancer Immunotherapy.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 6, p. 1, doi. 10.1111/cbdd.70141

By:

Cheng, Binbin;
Liu, Ting;
Cao, Hao;
Liu, Jin;
Ren, Yichang;
Huang, Junli;
Kong, Dulin;
Chen, Ting;
Liu, Yong;
Chen, Jianjun

Publication type:

Article

Tailored therapies: Exploring macromolecule based delivery science for personalized medicine.

Published in:

Journal of Macromolecular Science: Physics, 2025, v. 64, n. 8, p. 948, doi. 10.1080/00222348.2024.2372946

By:

Singh, Dilpreet

Publication type:

Article

Tissue-Specific Fluorescent Protein Turnover in Free-Moving Flies.

Published in:

Insects (2075-4450), 2025, v. 16, n. 6, p. 583, doi. 10.3390/insects16060583

By:

Bell, Katherine S.;
Ko, Sebastian;
Ali, Sam;
Bognar, Brett;
Khmelkov, Michael;
Rau, Nick;
Peng, Oscar K.;
Eyuboglu, Mavi;
Paine, John;
Tong, Andy;
Saria, Anuj;
Agrawal, Siddharth;
Davies, Kelvin J. A.;
Tower, John

Publication type:

Article

Combination of Rhamnetin and RXP03 Mitigates Venom-Induced Toxicity in Murine Models: Preclinical Insights into Dual-Target Antivenom Therapy.

Published in:

Toxins, 2025, v. 17, n. 6, p. 280, doi. 10.3390/toxins17060280

By:

Zhao, Jianqi;
Liu, Guangyao;
Shi, Xiao;
Huang, Chunhong

Publication type:

Article

A Comprehensive Quality Evaluation System for Medicinal Leeches by Integrating Macromolecular Protein Analysis and Small-Molecule Marker Detection as Well as Quantitative Bioassays.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 887, doi. 10.3390/ph18060887

By:

Wang, Wenduan;
Liu, Yufei;
Lou, Wenjiao;
Chen, Liangmian;
Xie, Tianze;
Wang, Zhimin;
Ma, Yue;
Gao, Huimin

Publication type:

Article

Comprehensive Metabolomic Profiling of Common Bean (Phaseolus vulgaris L.) Reveals Biomarkers Involved in Viral Disease Detection and Monitoring.

Published in:

International Journal of Plant Biology, 2025, v. 16, n. 2, p. 43, doi. 10.3390/ijpb16020043

By:

Osogo, Aggrey Keya;
Wekesa, Clabe;
Muyekho, Francis N.;
Were, Hassan Karakacha;
Okoth, Patrick

Publication type:

Article

The Role of Bacteriophage-Derived Small RNA Molecules in Bacterial and Phage Interactions.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 834, doi. 10.3390/v17060834

By:

Lewandowska, Natalia;
Bloch, Sylwia;
Łukasiak, Aleksandra;
Wesołowski, Wojciech;
Węgrzyn, Grzegorz;
Nejman-Faleńczyk, Bożena

Publication type:

Article

Discovery of Small Molecules Against Foot-and-Mouth Disease Virus Replication by Targeting 2C Helicase Activity.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 6, p. 785, doi. 10.3390/v17060785

By:

Zhou, Saisai;
Mu, Suyu;
Yu, Shuqi;
Tian, Yang;
Lu, Sijia;
Li, Zhen;
Wu, Hao;
Zhao, Jiaying;
Chen, Huanchun;
Sun, Shiqi;
Song, Yunfeng

Publication type:

Article

Functional Amyloid Formation within Mammalian Tissue.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0040006

By:

Fowler, Douglas M;
Koulov, Atanas V;
Alory-Jost, Christelle;
Marks, Michael S;
Balch, William E;
Kelly, Jeffery W

Publication type:

Article