Works matching DE "SMAD proteins"

Results: 705

Palmitate-increased TGF-β1 Gene Expression and p-Smad2/3 Protein Levels Attenuated by Chicoric Acid in Patients with Type 2 Diabetes Mellitus.

Published in:

Reports of Biochemistry & Molecular Biology, 2025, v. 13, n. 4, p. 540

By:

Sadeghabadi, Zahra Arab;
Ziamajidi, Nasrin;
Abbasalipourkabir, Roghayeh;
khajehahmadi, Zohreh;
Mohagheghi, Sina;
Tayebinia, Heidar;
Mohseni, Roohollah

Publication type:

Article

HMGA2 调控 TGF-β/Smad 信号通路促进喉癌增殖、侵袭及转移.

Published in:

Cancer Research on Prevention & Treatment, 2025, v. 52, n. 7, p. 571, doi. 10.3971/j.issn.1000-8578.2025.24.1216

By:

文献学;
李汝婷;
伍希;
郭仁彬;
伍君;
马丽娟

Publication type:

Article

PGC1α regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05790-x

By:

Zou, Minwen;
Ye, Kaichuang;
Yan, Jing;
Zhang, Shoumin;
Bao, Han;
Li, Zhiyin;
Tao, Yuting;
Zhang, Xing;
Tian, Wenhao;
Qi, Yingxin;
Huo, Yunlong;
Han, Yue

Publication type:

Article

Role of the TGF-β/Smad3 pathway in pancreatic cancer cell growth and stem cell characteristics.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03220-9

By:

Zhang, Yanling;
Chen, Qianya;
Chen, Danna;
Yang, Guangda

Publication type:

Article

Promoter methylation correlates with reduced SMAD4 expression in patients with breast cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02966-6

By:

Chaudhary, Archana;
Kumar, Manish;
Mohan, Lalit;
Haque, Rizwanul;
Prabhakar, Pankaj;
Ola, Mohammad Shamsul;
Ahmad, Md. Margoob

Publication type:

Article

SMAD3 orchestrates RNF167 and STAMBPL1-mediated Sestrin2 ubiquitination to drive gastric cancer progression.

Published in:

Cell Division, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13008-025-00163-z

By:

Zhang, Ning;
Zhao, Na;
Zhang, Hainan;
Yao, Le;
Si, Hongtao

Publication type:

Article

TGF-β/SMAD Pathway Mediates Cadmium Poisoning-Induced Chicken Liver Fibrosis and Epithelial-Mesenchymal Transition.

Published in:

Biological Trace Element Research, 2025, v. 203, n. 4, p. 2295, doi. 10.1007/s12011-024-04294-2

By:

Zhang, Jinyang;
Sun, Yiming;
Yu, Miao;
Hu, Yihan;
Huang, Xiaodan;
Yang, Guijun;
Zhang, Ruili;
Ge, Ming

Publication type:

Article

Retraction: Porphyromonas gingivalis promotes progression of esophageal squamous cell cancer via TGFβ-dependent Smad/YAP/TAZ signaling.

Published in:: 2022
Publication type:: Correction Notice

SMAD dependent signaling plays a detrimental role in a fly model of SMARCB1-deficiency and the biology of atypical teratoid/rhabdoid tumors.

Published in:

Journal of Neuro-Oncology, 2017, v. 131, n. 3, p. 477, doi. 10.1007/s11060-016-2326-3

By:

Jeibmann, Astrid;
Schulz, Jacqueline;
Eikmeier, Kristin;
Johann, Pascal;
Thiel, Katharina;
Tegeder, Isabel;
Ambrée, Oliver;
Frühwald, Michael;
Pfister, Stefan;
Kool, Marcel;
Paulus, Werner;
Hasselblatt, Martin

Publication type:

Article

Antifibrotic Effect of Smad Decoy Oligodeoxynucleotide in a CCl4-Induced Hepatic Fibrosis Animal Model.

Published in:

Molecules, 2018, v. 23, n. 8, p. 1991, doi. 10.3390/molecules23081991

By:

Gwon, Mi-Gyeong;
Kim, Jung-Yeon;
An, Hyun-Jin;
Kim, Woon-Hae;
Gu, Hyemin;
Park, Kwan-Kyu;
Kim, Min-Kyung;
Pak, Sok Cheon

Publication type:

Article

BMP-2 regulates the expression of myosin Va via smad in melan-a melanocyte.

Published in:

Archives of Dermatological Research, 2024, v. 316, n. 6, p. 1, doi. 10.1007/s00403-024-02955-9

By:

Park, Ji Yun;
Jo, Chan Song;
Ku, ChangHoe;
Hwang, Jae Sung

Publication type:

Article

The effect of ultraviolet radiation on the transforming growth factor beta 1/Smads pathway and p53 in actinic keratosis and normal skin.

Published in:

Archives of Dermatological Research, 2013, v. 305, n. 9, p. 777, doi. 10.1007/s00403-013-1361-6

By:

Xu, Dan;
Yuan, Ruihong;
Gu, Hua;
Liu, Tongyun;
Tu, Ying;
Yang, Zhi;
He, Li

Publication type:

Article

Mechanosignaling pathways in cutaneous scarring.

Published in:

Archives of Dermatological Research, 2012, v. 304, n. 8, p. 589, doi. 10.1007/s00403-012-1278-5

By:

Huang, Chenyu;
Akaishi, Satoshi;
Ogawa, Rei

Publication type:

Article

MEGF6 Promotes the Epithelial-to-Mesenchymal Transition via the TGFβ/SMAD Signaling Pathway in Colorectal Cancer Metastasis.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 46, n. 5, p. 1895, doi. 10.1159/000489374

By:

Hanqing Hu;
Meng Wang;
Hongwei Wang;
Zheng Liu;
Xu Guan;
Runkun Yang;
Rui Huang;
Qingchao Tang;
Chaoxia Zou;
Guiyu Wang;
Xu Gao;
Xishan Wang

Publication type:

Article

MicroRNA-27a Suppresses Detrusor Fibrosis in Streptozotocin-Induced Diabetic Rats by Targeting PRKAA2 Through the TGF-β1/Smad3 Signaling Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 45, n. 4, p. 1333, doi. 10.1159/000487560

By:

Jing Wu;
Shang Liu;
Zhi-Wei Yuan;
Jian-He Liu;
Jiong-Ming Li;
Tao Chen;
Ke-Wei Fang

Publication type:

Article

Hypoxia Suppresses TGF-B1-Induced Cardiac Myocyte Myofibroblast Transformation by Inhibiting Smad2/3 and Rhoa Signaling Pathways.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 45, n. 1, p. 250, doi. 10.1159/000486771

By:

Yan, Zhankui;
Shen, Daifei;
Liao, Jilin;
Zhang, Yanmei;
Chen, Yicun;
Shi, Ganggang;
Gao, Fenfei

Publication type:

Article

MicroRNA-196b Inhibits Cell Growth and Metastasis of Lung Cancer Cells by Targeting Runx2.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 43, n. 2, p. 757, doi. 10.1159/000481559

By:

Bai, Xiaoxue;
Meng, Lin;
Sun, Huijie;
Li, Zhuo;
Zhang, Xiufang;
Hua, Shucheng

Publication type:

Article

TGF-β1 Induces EMT in Bovine Mammary Epithelial Cells Through the TGFβ1/Smad Signaling Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 43, n. 1, p. 82, doi. 10.1159/000480321

By:

Qing Chen;
Wei Yang;
Xixi Wang;
Xueru Li;
Shaopei Qi;
Yong Zhang;
Ming-Qing Gao

Publication type:

Article

Identification of Tisp40 as an Essential Regulator of Renal Tubulointerstitial Fibrosis via TGF-β/Smads Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 42, n. 2, p. 697, doi. 10.1159/000477887

By:

Xiao, Cheng-cheng;
Zhang, Jie;
Luo, Peng-cheng;
Qin, Cong;
Du, Yang;
Ning, Jin-zhuo;
Zheng, Hai-zhou

Publication type:

Article

MALAT1 Modulates TGF-β1-Induced Endothelial-to-Mesenchymal Transition through Downregulation of miR-145.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 41, n. 5, p. 357, doi. 10.1159/000477479

By:

Yin Xiang;
Yachen Zhang;
Yong Tang;
Qianhui Li

Publication type:

Article

Bleomycin Suppresses the Proliferation and the Mobility of Human Gastric Cancer Cells Through the Smad Signaling Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 40, n. 3/4, p. 1401, doi. 10.1159/000453192

By:

Jin-fang Liu;
Xiao-cui Nie;
You-cheng Shao;
Wen-hui Su;
Hai-ying Ma;
Xiao-yan Xu

Publication type:

Article

Smad2/3/4 Pathway Contributes to TGF-β-Induced MiRNA-181b Expression to Promote Gastric Cancer Metastasis by Targeting Timp3.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 2, p. 453, doi. 10.1159/000445638

By:

Zhou, Qi;
Zheng, Xiao;
Chen, Lujun;
Xu, Bin;
Yang, Xin;
Jiang, Jingting;
Wu, Changping

Publication type:

Article

MicroRNA-21 Regulates Non-Small Cell Lung Cancer Cell Invasion and Chemo-Sensitivity through SMAD7.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 38, n. 6, p. 2152, doi. 10.1159/000445571

By:

Lin, Lei;
Tu, Hong-bin;
Wu, Liang;
Liu, Ming;
Jiang, Ge-ning

Publication type:

Article

Regulation of Oral Squamous Cell Carcinoma Proliferation Through Crosstalk Between SMAD7 and CYLD.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 38, n. 5, p. 1209, doi. 10.1159/000443069

By:

Wei-Li Ge;
Jun-Feng Xu;
Jun Hu

Publication type:

Article

Effects of Astragaloside IV Against the TGF-β1-Induced Epithelial-to-Mesenchymal Transition in Peritoneal Mesothelial Cells by Promoting Smad 7 Expression.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2015, v. 37, n. 1, p. 43, doi. 10.1159/000430332

By:

Zhang, Lu;
Li, Zhenghong;
He, Weiming;
Xu, Lingdong;
Wang, Jing;
Shi, Jun;
Sheng, Meixiao

Publication type:

Article

N-Acetylneuraminic acid enhances various collagen promoters' activity and increases their transcriptional level by activating the TGF-β/Smad signaling pathway.

Published in:

SOFW Journal (English version), 2024, v. 150, n. 12, p. 45

By:

Li, M.;
Xi, S.;
Zuo, Y.;
Lu, S.;
Li, X.

Publication type:

Article

Pingxiao pian attenuate invasiveness and proliferation of lung adenocarcinoma through regulating miR-29b-3p/TGF-β1/Smad/EMT pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01959-9

By:

Feng, Jie-Ni;
Chen, Pei-Rui;
Yuan, Shao-Fei;
Dai, Qiang;
Zheng, Wei-E.;
Lin, Hua-Long

Publication type:

Article

Integrated multi-omics characterization of SMAD4 mutant colorectal cancer.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01268-7

By:

Zhao, Danyi;
Qu, Yanjun;
Gao, Na;
Wu, Tao

Publication type:

Article

Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-05898-z

By:

Liao, Zian;
Tang, Suni;
Jiang, Peixin;
Geng, Ting;
Cope, Dominique I.;
Dunn, Timothy N.;
Guner, Joie;
Radilla, Linda Alpuing;
Guan, Xiaoming;
Monsivais, Diana

Publication type:

Article

The Cavin-1/Caveolin-1 interaction attenuates BMP/Smad signaling in pulmonary hypertension by interfering with BMPR2/Caveolin-1 binding.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-023-05693-2

By:

Tomita, Shinya;
Nakanishi, Naohiko;
Ogata, Takehiro;
Higuchi, Yusuke;
Sakamoto, Akira;
Tsuji, Yumika;
Suga, Takaomi;
Matoba, Satoaki

Publication type:

Article

Masking Epistasis Between MYC and TGF-β Pathways in Antiangiogenesis-Mediated Colon Cancer Suppression.

Published in:

JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 4, p. 1, doi. 10.1093/jnci/dju043

By:

Dews, Michael;
Tan, Grace S.;
Hultine, Stacy;
Raman, Pichai;
Choi, Jaewoo;
Duperret, Elizabeth K.;
Lawler, Jack;
Bass, Adam;
Thomas-Tikhonenko, Andrei

Publication type:

Article

SMAD4 and TGFβ are architects of inverse genetic programs during fate determination of antiviral CTLs.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.76457

By:

Chandiran, Karthik;
Suarez-Ramirez, Jenny E.;
Yinghong Hu;
Jellison, Evan R.;
Zeynep Ugur;
Jun-Siong Low;
McDonald, Bryan;
Kaech, Susan M.;
Cauley, Linda S.

Publication type:

Article

Arl15 upregulates the TGFß family signaling by promoting the assembly of the Smad-complex.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.76146

By:

Meng Shi;
Hieng Chiong Tie;
Mahajan Divyanshu;
Xiuping Sun;
Yan Zhou;
Boon Kim Boh;
Vardy, Leah A.;
Lei Lu

Publication type:

Article

Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75023

By:

Sautchuk, Rubens;
Kalicharan, Brianna H.;
Escalera-Rivera, Katherine;
Jonason, Jennifer H.;
Porter, George A.;
Awad, Hani A.;
Eliseev, Roman A.

Publication type:

Article

RETRACTION: lncRNA NEAT1/miR‐495‐3p Regulates Angiogenesis in Burn Sepsis Through the TGF‐β1 and SMAD Signaling Pathways.

Published in:: Immunity, Inflammation & Disease, 2025, v. 13, n. 3, p. 1, doi. 10.1002/iid3.70177
Publication type:: Article

Expression of MSTN/Smad signaling pathway genes and its association with meat quality in Tibetan sheep (Ovis aries).

Published in:

Food Science & Nutrition, 2023, v. 11, n. 4, p. 1836, doi. 10.1002/fsn3.3216

By:

He, Na;
Lang, Xia;
Wang, Cailian;
Lv, Cailing;
Li, Mingming;
Sun, Ruizhe;
Zhang, Junxia

Publication type:

Article

Propolis compound inhibits profibrotic TGF-β1/SMAD signalling in human fibroblasts.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07918-2

By:

Randall, Lisa J.;
Bajan, Sarah;
Tran, Trong D.;
Harvey, Robert J.;
Russell, Fraser D.

Publication type:

Article

RUNX2 mediated epithelial mesenchymal transition induced by TGF beta and Smad signaling promotes malignant progression in glioma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09167-9

By:

Zhou, Peng;
Wei, Qianfeng;
Wang, Haoqian;
Yu, Tao;
Chen, Lin;
Huang, Qiliang;
Wei, Li;
Jiang, Jingting

Publication type:

Article

Knockdown of LncRNA H19 inhibits vascularization and endochondral ossification via the MiRNA-21a-5p-Smad7/p-Smad2/3 pathway in fracture repair.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11300-7

By:

Sun, Qiuyue;
Zhang, Chen;
Chen, Bowen;
Liao, Junyi;
Bao, Aowen;
Zhao, Chen;
Chen, Hong;
He, Dawei;
Huang, Wei;
Dai, Guangming

Publication type:

Article

Zhilong Huoxue Tongyu capsule inhibits hypertensive myocardial fibrosis via balancing TGF-β1/Smad3/Erbb4-IR/miR-29b pathway.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10631-9

By:

Liu, Qiuyu;
Zhang, Dingshan;
Wang, Raoqiong;
Sun, Shihan;
Li, Yuanyuan;
Wan, Zhenxun;
Qian, Yumei;
Yang, Xinrui;
Luo, Gang;
Chen, Mingtai;
Liu, Mengnan

Publication type:

Article

Smad4 and TGFβ1 dependent gene expression signatures in conditional intestinal adenoma, organoids and colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-00908-4

By:

Surakhy, Mirvat;
Matheson, Julia;
Barnes, David J.;
Carter, Emma J.;
Hughes, Jennifer;
Bühnemann, Claudia;
Sanegre, Sabina;
Morreau, Hans;
Metz, Paul;
Imianowski, Charlotte J.;
Hassan, Andrew Bassim

Publication type:

Article

Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep03420

By:

Yoshitomo Honda;
Xianting Ding;
Mussano, Federico;
Wiberg, Akira;
Chih-ming Ho;
lchiro Nishimura

Publication type:

Article

Low Transforming Growth Factor-β Pathway Activity in Cervical Adenocarcinomas.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.797453

By:

Marvin, Dieuwke L.;
Spaans, Vivian M.;
de Kroon, Cor D.;
Slieker, Roderick C.;
Khelil, Maryam;
ten Dijke, Peter;
Ritsma, Laila;
Jordanova, Ekaterina S.

Publication type:

Article

Author Correction: Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis.

Published in:

2025

By:

Singh, Pratibha;
Sun, Jiangming;
Cavalera, Michele;
Al-Sharify, Dania;
Matthes, Frank;
Barghouth, Mohammad;
Tengryd, Christoffer;
Dunér, Pontus;
Persson, Ana;
Sundius, Lena;
Nitulescu, Mihaela;
Bengtsson, Eva;
Rattik, Sara;
Engelbertsen, Daniel;
Orho-Melander, Marju;
Nilsson, Jan;
Monaco, Claudia;
Goncalves, Isabel;
Edsfeldt, Andreas

Publication type:

Correction Notice

A stepwise mode of TGFβ-SMAD signaling and DNA methylation regulates naïve-to-primed pluripotency and differentiation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54433-5

By:

Zhao, Bingnan;
Yu, Xiuwei;
Shi, Jintong;
Ma, Shuangyu;
Li, Shizhao;
Shi, Haitao;
Xia, Shoubing;
Ye, Youqiong;
Zhang, Yongchun;
Du, Yanhua;
Wang, Qiong

Publication type:

Article

VHL-recruiting PROTAC attenuates renal fibrosis and preserves renal function via simultaneous degradation of Smad3 and stabilization of HIF-2α.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00936-x

By:

Yang, Jiayi;
Ruan, Yuyi;
Wang, Dan;
Fan, Jinjin;
Luo, Ning;
Chen, Huiting;
Li, Xiaoyan;
Chen, Wei;
Wang, Xin

Publication type:

Article

Retracted: The Effect of Acute Kidney Injury on TGF-β1 and Smad3 in Patients with Coronary Heart Disease after Off-Pump Coronary Artery Bypass Grafting.

Published in:

2023

By:

Engineering, Journal of Healthcare

Publication type:

Correction Notice

Exploring the Effect of Lutein on TGF-β/ SMAD2 Signalling Molecule Gene Expression in Lung Cancer Cells: An In-vitro Study.

Published in:

Journal of Clinical & Diagnostic Research, 2024, v. 18, n. 7, p. 7, doi. 10.7860/JCDR/2024/69657.19649

By:

AASHRUTHAA, SEKAR;
ROY, ANITHA;
ELUMALAI, PERUMAL

Publication type:

Article

SMAD2 S-palmitoylation promotes its linker region phosphorylation and T<sub>H</sub>17 cell differentiation in a mouse model of multiple sclerosis.

Published in:

Science Signaling, 2025, v. 18, n. 888, p. 1, doi. 10.1126/scisignal.adr2008

By:

Zhang, Mingming;
Yu, Tao;
Liu, Yinong;
Lu, Xuan;
Chen, Wenzhe;
Zhou, Lixing;
Xu, Yuejie;
Yang, Min;
Miller, Andrew D.;
Lin, Hening

Publication type:

Article

Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification.

Published in:

Science Signaling, 2023, v. 16, n. 781, p. 1, doi. 10.1126/scisignal.add5750

By:

Perovanovic, Jelena;
Wu, Yifan;
Abewe, Hosiana;
Shen, Zuolian;
Hughes, Erik P.;
Gertz, Jason;
Chandrasekharan, Mahesh B.;
Tantin, Dean

Publication type:

Article