Works matching DE "SIRTUINS"

Results: 2646

The Sirt1 Gene Promotes Insulin Secretion in Accord with Diet.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. 1, doi. 10.1371/journal.pbio.0040044

By:

Chanut, Françoise

Publication type:

Article

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. 1, doi. 10.1371/journal.pbio.0040031

By:

Bordone, Laura;
Motta, Maria Carla;
Picard, Frederic;
Robinson, Ashley;
Jhala, Ulupi S;
Apfeld, Javier;
McDonagh, Thomas;
Lemieux, Madeleine;
McBurney, Michael;
Szilvasi, Akos;
Easlon, Erin J;
Lin, Su-Ju;
Guarente, Leonard

Publication type:

Article

Resveratrol promotes bone mass in ovariectomized rats and the SIRT1 rs7896005 SNP is associated with bone mass in women during perimenopause and early postmenopause.

Published in:

Climacteric, 2023, v. 26, n. 1, p. 25, doi. 10.1080/13697137.2022.2073809

By:

Wang, X.;
Lu, C.;
Chen, Y.;
Wang, Q.;
Bao, X.;
Zhang, Z.;
Huang, X.

Publication type:

Article

Quantitative structure–activity relationship modeling reveals the minimal sequence requirement and amino acid preference of sirtuin-1's deacetylation substrates in diabetes mellitus.

Published in:

Journal of Bioinformatics & Computational Biology, 2022, v. 20, n. 3, p. 1, doi. 10.1142/S0219720022500081

By:

Shao, X.;
Kong, W.;
Li, Y.;
Zhang, S.

Publication type:

Article

Studying the Cytotoxic Activity of Newly Designed and Synthesized HDAC Inhibitors Derivatives of Pentanoyl Anilide‐5‐Biguanide.

Published in:

Macromolecular Symposia, 2022, v. 401, n. 1, p. 1, doi. 10.1002/masy.202100346

By:

Sagheer, Othman Makki;
Mohammed, Mohammed Hassan;
Wadi, Jaafar S.;
Ibraheem, Zaid O.

Publication type:

Article

Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway.

Published in:

Biotechnology Letters, 2018, v. 40, n. 3, p. 509, doi. 10.1007/s10529-017-2493-0

By:

Lee, Hyunjin;
Kim, Minji;
Park, Yun-Hee;
Park, Jun-Beom

Publication type:

Article

Overexpression of Sirtuin2 prevents high glucose-induced vascular endothelial cell injury by regulating the p53 and NF-κB signaling pathways.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 271, doi. 10.1007/s10529-017-2487-y

By:

Zhang, Wenguang;
Liu, Dongmei;
Ren, Jianzhuang;
Zhou, Pengli;
Han, Xinwei

Publication type:

Article

No significant association between SIRT1 gene and methamphetamine-induced psychosis in the Japanese population.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2011, v. 26, n. 7, p. 445, doi. 10.1002/hup.1223

By:

Kishi, Taro;
Fukuo, Yasuhisa;
Okochi, Tomo;
Kitajima, Tsuyoshi;
Ujike, Hiroshi;
Inada, Toshiya;
Yamada, Mitsuhiko;
Uchimura, Naohisa;
Sora, Ichiro;
Iyo, Masaomi;
Ozaki, Norio;
Correll, Christoph U.;
Iwata, Nakao

Publication type:

Article

Tissue-specific gene expression and fasting regulation of sirtuin family in gilthead sea bream ( Sparus aurata).

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2017, v. 187, n. 1, p. 153, doi. 10.1007/s00360-016-1014-0

By:

Simó-Mirabet, Paula;
Bermejo-Nogales, Azucena;
Calduch-Giner, Josep;
Pérez-Sánchez, Jaume

Publication type:

Article

Rs12778366 single nucleotide polymorphism of Sirtuin 1 (SIRT1) and response to resveratrol supplementation in patients with type 2 diabetes mellitus.

Published in:

Acta Diabetologica, 2019, v. 56, n. 8, p. 963, doi. 10.1007/s00592-019-01341-6

By:

Gambino, Roberto;
Fanni, Giovanni;
Togliatto, Gabriele;
Ponzo, Valentina;
Goitre, Ilaria;
Cassader, Maurizio;
Brizzi, Maria Felice;
Bo, Simona

Publication type:

Article

SIRT3 Promotes the Development of Esophageal Squamous Cell Carcinoma by Regulating Hexokinase 2 through the AKT Signaling Pathway.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 174, n. 1, p. 81, doi. 10.1007/s10517-022-05653-6

By:

Yuan, M. L.;
Ren, L. H.;
Yu, X. C.;
Dong, J. W.;
Shi, R. H.

Publication type:

Article

Features Neurohumoral and Immune Profile in Children with Functional Disorders of the Autonomic Nervous System Associated with Sirtuin Gene SIRT1 (rs7069102) Polymorphism.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 172, n. 5, p. 583, doi. 10.1007/s10517-022-05439-w

By:

Dolgikh, О. V.;
Zaitseva, N. V.;
Nikonoshina, N. A.

Publication type:

Article

Knockdown of Sirt1 Gene in Mice Results in Lipid Accumulation in the Liver Mediated via PGC-1α-Induced Mitochondrial Dysfunction and Oxidative Stress.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 172, n. 2, p. 180, doi. 10.1007/s10517-021-05359-1

By:

Yang, H.;
Liu, Y.;
Wang, Y.;
Xu, S.;
Su, D.

Publication type:

Article

Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva.

Published in:

Bulletin of Experimental Biology & Medicine, 2020, v. 169, n. 6, p. 821, doi. 10.1007/s10517-020-04986-4

By:

Pukhalskaia, A. E.;
Dyatlova, A. S.;
Linkova, N. S.;
Kozlov, K. L.;
Kvetnaia, T. V.;
Koroleva, M. V.;
Kvetnoy, I. M.

Publication type:

Article

The Role of Urokinase, Tumor Necrosis Factor, and Matrix Metalloproteinase-9 in Monocyte Activation.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 492, doi. 10.1007/s10517-019-04557-2

By:

Menshikov, M. Yu.;
Stafeev, I. S.;
Zubkova, E. S.;
Beloglazova, I. B.;
Ratner, E. I.;
Dergilev, K. V.;
Parfyonova, E. V.

Publication type:

Article

Modulation of the Inflammatory Status of Macrophages and Their Paracrine Effect on the Sensitivity of Adipocytes to Insulin with Sirtuin and PPARγ Receptor Activators.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 165, n. 4, p. 429, doi. 10.1007/s10517-018-4186-7

By:

Stafeev, Yu. S.;
Michurina, S. S.;
Zubkova, E. S.;
Beloglazova, I. B.;
Ratner, E. I.;
Parfenova, E. V.;
Men’shikov, M. Yu.

Publication type:

Article

Expression of Signal Molecules in Culture of Human Endothelial Cells in Atherosclerosis and Restenosis.

Published in:

Bulletin of Experimental Biology & Medicine, 2017, v. 163, n. 4, p. 566, doi. 10.1007/s10517-017-3850-7

By:

Kozlov, K.;
Bolotov, I.;
Lin'kova, N.;
Drobintseva, A.

Publication type:

Article

Ganoderma lucidum polysaccharides protect against sepsis-induced cardiac dysfunction by activating SIRT1.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 1, p. 124, doi. 10.1093/jpp/rgab142

By:

Xu, Zhong-Heng;
Su, Xiao;
Yang, Geng;
Qin, Tao;
Liu, Yu

Publication type:

Article

Pioglitazone Protects Against Acetic Acid–Induced Ulcerative Colitis in Rats via Modulation of Sirt1 / Nox4 Signaling and Suppression of Macrophage M1 Polarization.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 6, p. 2429, doi. 10.21608/ZUMJ.2024.298041.3447

By:

Kabil, Soad L.;
Abdelrahman, Abeer A.

Publication type:

Article

RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00451-4

By:

Liu, Hanye;
Yan, Guanghai;
Li, Li;
Wang, Dandan;
Wang, Yu;
Jin, Shan;
Jin, Zhehu;
Li, Liangchang;
Zhu, Lianhua

Publication type:

Article

Neurodegenerative disease: Preventing 'SIRTain' death by mutant huntingtin.

Published in:

2012

By:

Flight, Monica Hoyos

Publication type:

journal article

Klotho enhances diastolic function in aged hearts through Sirt1-mediated pathways.

Published in:

GeroScience, 2024, v. 46, n. 5, p. 4729, doi. 10.1007/s11357-024-01209-w

By:

Daneshgar, Nastaran;
Lan, Renny;
Regnier, Michael;
Mackintosh, Samuel G.;
Venkatasubramanian, Ravinandan;
Dai, Dao-Fu

Publication type:

Article

Cellular metabolic pathways of aging in dogs: could p53 and SIRT1 be at play?

Published in:

GeroScience, 2024, v. 46, n. 2, p. 1895, doi. 10.1007/s11357-023-00942-y

By:

Jiménez, Ana Gabriela;
Paul, Kailey D.;
Benson, Mitchel;
Lalwani, Sahil;
Cipolli, William

Publication type:

Article

SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence.

Published in:

GeroScience, 2024, v. 46, n. 1, p. 1107, doi. 10.1007/s11357-023-00863-w

By:

Yu, An;
Yu, Ruofan;
Liu, Haiying;
Ge, Chenliang;
Dang, Weiwei

Publication type:

Article

Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity.

Published in:

GeroScience, 2022, v. 44, n. 3, p. 1505, doi. 10.1007/s11357-022-00559-7

By:

Wang, Zhizhen;
Zheng, Peng;
Chen, Xi;
Xie, Yuanyi;
Weston-Green, Katrina;
Solowij, Nadia;
Chew, Yee Lian;
Huang, Xu-Feng

Publication type:

Article

Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock.

Published in:

GeroScience, 2021, v. 43, n. 3, p. 1217, doi. 10.1007/s11357-020-00311-z

By:

Sims, Carrie A.;
Labiner, Hanna E.;
Shah, Sohini S.;
Baur, Joseph A.

Publication type:

Article

Aging alters acetylation status in skeletal and cardiac muscles.

Published in:

GeroScience, 2020, v. 42, n. 3, p. 963, doi. 10.1007/s11357-020-00171-7

By:

Yeo, Dongwook;
Kang, Chounghun;
Ji, Li Li

Publication type:

Article

Tanshinone IIA inhibits the apoptosis process of nerve cells by upshifting SIRT1 and FOXO3α protein and regulating anti- oxidative stress molecules and inflammatory factors in cerebral infarction model.

Published in:

Immunopharmacology & Immunotoxicology, 2025, v. 47, n. 1, p. 23, doi. 10.1080/08923973.2024.2428662

By:

Xu, Jiao;
Liu, Xiufeng;
Yu, Heng;
Wang, Zhenyu

Publication type:

Article

Sirt1/Nrf2/TNFα; TLR4/Myd88/NF-κB signaling pathways are involved in mediating hepatoprotective effect of bupropion in rat model of myocardial infarction.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 6, p. 872, doi. 10.1080/08923973.2024.2415461

By:

Abdelzaher, Walaa Yehia;
Geddawy, Ayman;
Attya, Mina Ezzat;
Ali, Abdel Hamid Sayed AboBakr;
Elroby Ali, Doaa Mohamed;
Waggas, Dania S.;
Alshaeri, Heba K.;
Ibrahim, Yasmine F.

Publication type:

Article

Sirtinol, a SIRT1 inhibitor, inhibits the EMT and metastasis of 4T1 breast cancer cells and impacts the tumor microenvironment.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 6, p. 829, doi. 10.1080/08923973.2024.2412110

By:

Satam, Sharvari;
Palekar, Nitya;
Premkumar, Kavitha;
Shankar, Bhavani S.

Publication type:

Article

Sirtuins: exploring next-gen therapeutics in the pathogenesis osteoporosis and associated diseases.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 3, p. 277, doi. 10.1080/08923973.2024.2315418

By:

Waykar, Tejal R.;
Mandlik, Satish K.;
Mandlik, Deepa S.

Publication type:

Article

Neuroprotective effect of canagliflozin against cisplatin-induced cerebral cortex injury is mediated by regulation of HO-1/PPAR-γ, SIRT1/FOXO-3, JNK/AP-1, TLR4/iNOS, and Ang II/Ang 1–7 signals.

Published in:

Immunopharmacology & Immunotoxicology, 2023, v. 45, n. 3, p. 304, doi. 10.1080/08923973.2022.2143371

By:

Hassanein, Emad H. M.;
Saleh, Fayez M.;
Ali, Fares E. M.;
Rashwan, Eman K.;
Atwa, Ahmed M.;
Abd El-Ghafar, Omnia A. M.

Publication type:

Article

Resveratrol-poor Red Wines Modulate SIRT1 in Human Renal Cells.

Published in:

Plant Foods for Human Nutrition, 2012, v. 67, n. 3, p. 289, doi. 10.1007/s11130-012-0296-y

By:

Stiaccini, Giulia;
Mannari, Claudio;
Bertelli, Alberto;
Giovannini, Luca

Publication type:

Article

AAV-mediated upregulation of VDAC1 rescues the mitochondrial respiration and sirtuins expression in a SOD1 mouse model of inherited ALS.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01949-w

By:

Magrì, Andrea;
Lipari, Cristiana Lucia Rita;
Caccamo, Antonella;
Battiato, Giuseppe;
Conti Nibali, Stefano;
De Pinto, Vito;
Guarino, Francesca;
Messina, Angela

Publication type:

Article

Diminished NAD+ levels and activation of retrotransposons promote postovulatory aged oocyte (POAO) death.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01876-w

By:

Singh, Ajay K.;
Mohanty, Aradhana;
Kumar, S. Lava;
Kumari, Anjali;
Beniwal, Rohit;
Kumar Etikuppam, Ajith;
Birajdar, Pravin;
Mohd, Athar;
Prasada Rao, H. B. D.

Publication type:

Article

AGER1 deficiency-triggered ferroptosis drives fibrosis progression in nonalcoholic steatohepatitis with type 2 diabetes mellitus.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01477-z

By:

Gong, Yihui;
Liu, Zijun;
Zhang, Yuanyuan;
Zhang, Jun;
Zheng, Yin;
Wu, Zhongming

Publication type:

Article

The study of sirtuins in breast cancer patients before and after radiotherapy.

Published in:

Turkish Journal of Medical Sciences, 2021, v. 51, n. 3, p. 1354, doi. 10.3906/sag-2012-195

By:

HELVACI, Nazlı;
SARAÇOĞLU, Hatice;
YILDIZ, Oğuz Galip;
KILIÇ, Eser

Publication type:

Article

Relationship between SIRT1 gene expression level and disease in age-related cataract cases.

Published in:

Turkish Journal of Medical Sciences, 2019, v. 49, n. 4, p. 1068, doi. 10.3906/sag-1810-182

By:

AĞAOĞLU, Nihat Buğra;
VAROL, Nuray;
YILDIZ, Saliha Handan;
KARAOSMANOĞLU, Cem;
DUMAN, Rahmi;
ÖZDEMİR ERDOĞAN, Müjgan;
SOLAK, Mustafa

Publication type:

Article

Effects of Schumann resonance on the proliferation and migration of normal human epidermal keratinocytes and the expression of DEFB1 and SIRT1.

Published in:

Journal of Cosmetic Dermatology, 2024, v. 23, n. 2, p. 676, doi. 10.1111/jocd.15988

By:

Sugiwaki, Hidemi;
Kotani, Mayumi;
Fujita, Akihito;
Moriwaki, Shinichi

Publication type:

Article

Sonochemical Synthesis and In Silico Evaluation of Imidazo[1,2-a]Pyridine Derivatives as Potential Inhibitors of Sirtuins.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 4, p. 3741, doi. 10.1080/10406638.2022.2077774

By:

Ramarao, Sidda;
Pothireddy, Mohanreddy;
Venkateshwarlu, Rapolu;
Moturu, Krishna Murthy V. R.;
Siddaiah, Vidavalur;
Kapavarapu, Ravikumar;
Dandela, Rambabu;
Pal, Manojit

Publication type:

Article

Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease.

Published in:

Free Radical Research, 2011, v. 45, n. 8, p. 888, doi. 10.3109/10715762.2011.574290

By:

Ghosh, Nilanjan;
Ghosh, Rituparna;
Mandal, Subhash C.

Publication type:

Article

Sirtuin及其食源性激活剂对衰老相关疾病的调控作用研究进展.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2023, v. 23, n. 4, p. 390, doi. 10.16429/j.1009-7848.2023.04.036

By:

张涵;
尹淑涛;
扈洪波;
赵冲

Publication type:

Article

耗牛乳硬质干酪苦味肽RK7的抗氧化活性及其机制.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2022, v. 22, n. 8, p. 40, doi. 10.16429/j.1009-7848.2022.08.005

By:

杨保军;
梁琪;
宋雪梅

Publication type:

Article

Influence of narrow‐band ultraviolet B therapy on sirtuin 1 expression in lesional skin of patients with chronic plaque psoriasis: Relation to clinical improvement and interferon‐γ expression.

Published in:

Photodermatology, Photoimmunology & Photomedicine, 2022, v. 38, n. 6, p. 555, doi. 10.1111/phpp.12790

By:

Eid, Amira Abulfotooh;
Aly, Rania Gaber;
Elkholy, Shaimaa Abd Elkarim;
Sorour, Osama Ahmed

Publication type:

Article

Regulation of Gene Expression through Food—Curcumin as a Sirtuin Activity Modulator.

Published in:

Plants (2223-7747), 2022, v. 11, n. 13, p. 1741, doi. 10.3390/plants11131741

By:

Ungurianu, Anca;
Zanfirescu, Anca;
Margină, Denisa

Publication type:

Article

SIRT1 Activation Enhancing 8,3′-Neolignans from the Twigs of Corylopsis coreana Uyeki.

Published in:

Plants (2223-7747), 2021, v. 10, n. 8, p. 1684, doi. 10.3390/plants10081684

By:

Kim, Hyun-Woo;
Jeon, Jin-Bum;
Zhang, Mi;
Cho, Hyo-Moon;
Ryu, Byeol;
Lee, Ba-Wool;
Gerwick, William H.;
Oh, Won-Keun

Publication type:

Article

The complex role of SIRT7 in p53 stabilization: nucleophosmin joins the debate.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1896349

By:

Kumari, Poonam;
Tarighi, Shahriar;
Braun, Thomas;
Ianni, Alessandro

Publication type:

Article

Telomeres and sirtuins: at the end we meet again.

Published in:

2019

By:

Amano, Hisayuki;
Sahin, Ergun

Publication type:

Opinion

Water- soluble 4-(dimethylaminomethyl) heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX- SIRT1 axis and apoptosis in oral cancer cells.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87873

By:

Islam, Atikul;
Yu-Chun Chang;
Xiao-Chi Chen;
Chia-Wei Weng;
Chien-Yu Chen;
Che-Wei Wang;
Mu-Kuan Chen;
Tikhomirov, Alexander S.;
Shchekotikhin, Andrey E.;
Pin Ju Chueh

Publication type:

Article

Binding to nucleosome poises human SIRT6 for histone H3 deacetylation.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87989

By:

Smirnova, Ekaterina;
Bignon, Emmanuelle;
Schultz, Patrick;
Papai, Gabor;
Shem, Adam Ben

Publication type:

Article