Works matching DE "SIMVASTATIN"

Results: 1578

Chemical profile of Ficus lyrata bark extract and its therapeutic effect on non-alcoholic fatty liver disease via regulating oxidative stress, inflammation and hepatic lipogenesis.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-05010-w

By:

Mousa, Amria Mamdouh;
Taher, Rehab Fikry;
El-Sammad, Nermin Mohamed;
Balabel, Esraa Aly;
Youssef, Elham Mohamed;
Afifi, Ahmed Hassan;
Abdel-Rahman, Sahar Samir;
Anwar, Nayera;
Hassan, Sherien Kamal

Publication type:

Article

Synergistic activity of simvastatin and irinotecan chemotherapy against glioblastoma converges on TGF-β signaling.

Published in:

Journal of Neuro-Oncology, 2025, v. 174, n. 3, p. 621, doi. 10.1007/s11060-025-05089-8

By:

Yadav, Niket;
Xiao, Aizhen;
Zhong, Qing;
Kumar, Pankaj;
Konduru, Guruprasad;
Hart, William;
Lazzara, Matthew;
Purow, Benjamin

Publication type:

Article

Dexamethasone, celecoxib, and simvastatin-induced 5-fluorouracil resistance in cancer cells: a possible role of lipid droplet accumulation.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02593-1

By:

Sabbah, Duaa S.;
Ikhmais, Balqis A.;
Abdallah, Qasem M.;
Phillips, Roger M.;
Qinna, Nidal A.

Publication type:

Article

Simvastatin‐Release Photocurable Hydrogel With Microsphere Delivery System for Improved Dental Applications.

Published in:

Journal of Applied Polymer Science, 2025, v. 142, n. 32, p. 1, doi. 10.1002/app.57284

By:

Bronze‐Uhle, Erika S.;
Silva, Isabela S. P.;
Bordini, Ester A. F.;
Stuani, Vitor T.;
Melo, Camila C. S. B.;
de Toledo, Priscila T. A.;
Correa, Ligia E.;
Rinaldo, Daniel;
de Souza‐Costa, Carlos A.;
Lisboa‐Filho, Paulo N.;
Soares, Diana G.

Publication type:

Article

Hepatotoxicity associated with statins: A retrospective pharmacovigilance study based on the FAERS database.

Published in:

PLoS ONE, 2025, v. 19, n. 7, p. 1, doi. 10.1371/journal.pone.0327500

By:

Zhou, Lu;
Wu, Bin;
Bian, Yuan;
Lu, Yun;
Zou, Ya;
Lin, Shanshan;
Li, Qinchuan;
Liu, Chun

Publication type:

Article

Potential interactions between direct oral anticoagulants and atorvastatin/simvastatin: a cohort and case-crossover study.

Published in:

British Journal of General Practice, 2025, v. 75, n. 756, p. e466, doi. 10.3399/BJGP.2024.0349

By:

Wong, Angel YS;
Warren-Gash, Charlotte;
Bhaskaran, Krishnan;
Leyrat, Clémence;
Banerjee, Amitava;
Smeeth, Liam;
Douglas, Ian J

Publication type:

Article

Advancing the gold standard in offloading the diabetic foot.

Published in:

Diabetic Foot Journal, 2015, v. 18, n. 1, p. 31

By:

Sambrook, Emily;
Delpierre, Tom;
Bowen, Graham

Publication type:

Article

Editorial for 'Randomized controlled trial assessing the effect of simvastatin in primary biliary cirrhosis'.

Published in:

Liver International, 2014, v. 34, n. 3, p. 328, doi. 10.1111/liv.12359

By:

Stojakovic, Tatjana;
Claudel, Thierry;
Trauner, Michael

Publication type:

Article

Simvastatin inhibits oxidative stress via the activation of nuclear factor erythroid 2-related factor 2 signaling in trophoblast cells.

Published in:

Journal of Obstetrics & Gynaecology Research, 2016, v. 42, n. 1, p. 36, doi. 10.1111/jog.12876

By:

Chigusa, Yoshitsugu;
Kawasaki, Kaoru;
Kondoh, Eiji;
Mogami, Haruta;
Ujita, Mari;
Fujita, Kohei;
Tatsumi, Keiji;
Takeda, Satoru;
Konishi, Ikuo

Publication type:

Article

Adjunctive simvastatin has no significant benefit for treatment‐resistant depression.

Published in:: Brown University Psychopharmacology Update, 2023, v. 34, n. 6, p. 7, doi. 10.1002/pu.31026
Publication type:: Article

Hansen solubility parameters for assay method optimization of simvastatin, ramipril, atenolol, hydrochlorothiazide and aspirin in human plasma using liquid chromatography with tandem mass spectrometry.

Published in:

Journal of Separation Science, 2017, v. 40, n. 18, p. 3662, doi. 10.1002/jssc.201700565

By:

Devalapalli, Murali Mohan Reddy;
Cheruvu, Hanumanth Srikanth;
Yertha, Thejaswi;
Veeravalli, Vijaya Bhaskar;
Sampathi, Sunitha;
Shivakumar, Savithri

Publication type:

Article

Liquid chromatography with tandem mass spectrometry for the simultaneous identification and quantification of cardiovascular drugs applied to the detection of substandard and falsified drugs.

Published in:

Journal of Separation Science, 2015, v. 38, n. 4, p. 562, doi. 10.1002/jssc.201401301

By:

Bernard, Mélisande;
Akrout, Wiem;
Buu, Christelle Tran;
Metz, Carole;
Antignac, Marie;
Yagoubi, Najet;
Do, Bernard

Publication type:

Article

Statin resistance in Candida glabrata.

Published in:

Biotechnology Letters, 2018, v. 40, n. 9/10, p. 1389, doi. 10.1007/s10529-018-2597-1

By:

Subhan, Mishal;
Faryal, Rani;
Macreadie, Ian

Publication type:

Article

Exploring effects of Simvastatin on coagulation mediators to alleviate the advancement of high cholesterol diet triggered neurodegeneration.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 6, p. 1, doi. 10.1002/jbt.23342

By:

Khan, Sana;
Hasan, Noorul;
Khan, Saba;
Akhtar, Mymoona;
Akhtar, Mohammad;
Najmi, Abul Kalam

Publication type:

Article

Effect of simvastatin on intestinal recovery following gut ischemia-reperfusion injury in a rat.

Published in:

2010

By:

Slijper, Nadav;
Sukhotnik, Igor;
Chemodanov, Elena;
Bashenko, Yulia;
Shaoul, Ron;
Coran, Arnold G.;
Mogilner, Jorge

Publication type:

journal article

Statin-induced calcific Achilles tendinopathy in rats: comparison of biomechanical and histopathological effects of simvastatin, atorvastatin and rosuvastatin.

Published in:

2017

By:

Kaleağasıoğlu, Ferda;
Olcay, Ercan;
Olgaç, Vakur;
Kaleağasıoğlu, Ferda;
Olgaç, Vakur

Publication type:

journal article

Porous Chitosan/Nano-Hydroxyapatite Composite Scaffolds Incorporating Simvastatin-Loaded PLGA Microspheres for Bone Repair.

Published in:

Cells Tissues Organs, 2018, v. 205, n. 1, p. 20, doi. 10.1159/000485502

By:

Li, Yu;
Zhang, Zhanzhao;
Zhang, Zhiyong

Publication type:

Article

Cryostructuring of Polymeric Systems: 68. Evaluation of Poly(vinyl alcohol) Composite Cryogels Filled with Poly(3-hydroxybutyric acid)-Based Microspheres of Different Porous Morphology as Potential Delivery Systems for Drugs of Various Water-Solubility †

Published in:

Gels (2310-2861), 2024, v. 10, n. 11, p. 734, doi. 10.3390/gels10110734

By:

Michurov, Dmitrii A.;
Andreasyan, Gagik A.;
Lozinsky, Vladimir I.

Publication type:

Article

Validated green spectroscopic manipulation of area under the curve (AUC) for estimation of Simvastatin: Application to nano-structured lipid carriers and niosomal systems.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, n. 1, p. 30, doi. 10.29228/jrp.285

By:

MANNAA, Islam M.;
EL GAZAYERLY, Omaima N.;
ABDELBARY, Aly A.;
SALEH, Sarah S.;
MOSTAFA, Dalia A.

Publication type:

Article

Diazepam, metformin, omeprazole and simvastatin: a full discussion of individual and mixture acute toxicity.

Published in:

Ecotoxicology, 2020, v. 29, n. 7, p. 1062, doi. 10.1007/s10646-020-02239-8

By:

Jacob, Raquel Sampaio;
de Souza Santos, Lucilaine Valéria;
d'Auriol, Mirna;
Lebron, Yuri Abner Rocha;
Moreira, Victor Rezende;
Lange, Liséte Celina

Publication type:

Article

Simvastatin Attenuates Cardiac Fibrosis via Regulation of Cardiomyocyte-Derived Exosome Secretion.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 6, p. 794, doi. 10.3390/jcm8060794

By:

Kuo, Hsuan-Fu;
Hsieh, Chong-Chao;
Wang, Shu-Chi;
Chang, Chia-Yuan;
Hung, Chih-Hsin;
Kuo, Po-Lin;
Liu, Yu-Ru;
Li, Chia-Yang;
Liu, Po-Len

Publication type:

Article

Repurposing Treatments to Enhance Innate Immunity. Can Statins Improve Neutrophil Functions and Clinical Outcomes in COPD?

Published in:

Journal of Clinical Medicine, 2016, v. 5, n. 10, p. 89, doi. 10.3390/jcm5100089

By:

Walton, Georgia M.;
Purvis, Thomas;
Sapey, Elizabeth;
Sadhra, Charandeep S.;
Stockley, James A.;
Griffiths, Diane

Publication type:

Article

Mitigation of Renal Injury in Wistar Rats Using Adipose Tissue-derived Mesenchymal Stromal Cells and Simvastatin.

Published in:

Journal of Urological Surgery, 2025, v. 12, n. 1, p. 1, doi. 10.4274/jus.galenos.2024.2024-10-2

By:

Boccasanta, Daniela;
Heldwein, Flavio Lobo;
Senegaglia, Alexandra;
Rebelatto, Carmen Lúcia Kuniyoshi;
Moura, Sérgio Adriane Bezerra de;
Fracaro, Leticia;
Brofman, Paulo Roberto Slud;
Pecoits-Filho, Roberto;
Meyer, Fernando

Publication type:

Article

Di-(2-ethylhexyl) Phthalate Limits the Lipid-Lowering Effects of Simvastatin by Promoting Protein Degradation of Low-Density Lipoprotein Receptor: Role of PPARγ-PCSK9 and LXRα-IDOL Signaling Pathways.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 477, doi. 10.3390/antiox12020477

By:

Guo, Bei-Chia;
Kuo, Ko-Lin;
Huang, Jenq-Wen;
Chen, Chia-Hui;
Tarng, Der-Cherng;
Lee, Tzong-Shyuan

Publication type:

Article

Simvastatin inhibits apoptosis of endothelial cells induced by sepsis through upregulating the expression of Bcl-2 and downregulating Bax.

Published in:

World Journal of Emergency Medicine, 2014, v. 5, n. 4, p. 291, doi. 10.5847/wjem.j.issn.1920-8642.2014.04.009

By:

Hui Fu;
Qiao-sheng Wang;
Qiong Luo;
Si Tan;
Hua Su;
Shi-lin Tang;
Zheng-liang Zhao;
Li-ping Huang

Publication type:

Article

BENEFITS OF PHARMACEUTICAL INNOVATION: THE CASE OF SIMVASTATIN IN CANADA.

Published in:

International Journal of Technology Assessment in Health Care, 2012, v. 28, n. 4, p. 390, doi. 10.1017/S0266462312000499

By:

Thanh, Nguyen Xuan;
Chuck, Anderson W.;
Ohinmaa, Arto;
Jacobs, Philip

Publication type:

Article

Understanding The Effect of Introducing Biopolymer at Two Distinct Phases During Homogenization in A Double Solvent Evaporation Technique: A Study Using Simvastatin as A Model Drug for Bone Tissue Regeneration.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2024, v. 20, p. 44

By:

Hidayah Mohamed, Nur Aliana;
Mohd Rawi, Ahmad Fareez;
Jaapar, Khairani

Publication type:

Article

Anti-inflammatory effect of simvastatin by impeding TNF-α and interleukin-1ß pathways: antiangiogenic activity of simvastatin and simvastatin-loaded silver nanoparticles.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2022, v. 50, n. 1, p. 208, doi. 10.1080/21691401.2022.2098306

By:

Buabeid, Manal;
Arafa, El-Shaimaa A.;
Yaseen, Hafiza Sidra;
Umar, Muhammad Ihtisham;
Murtaza, Ghulam

Publication type:

Article

Hybrid nanocarrier system for guiding and augmenting simvastatin cytotoxic activity against prostate cancer.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. S641, doi. 10.1080/21691401.2018.1505743

By:

Sedki, Mohammed;
Khalil, Islam A.;
El-Sherbiny, Ibrahim M.

Publication type:

Article

Thermoresponsive biodegradable HEMA-Lactate-Dextran-co-NIPA cryogels for controlled release of simvastatin.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2015, v. 43, n. 1, p. 40, doi. 10.3109/21691401.2013.837475

By:

Bölgen, Nimet;
Aguilar, Maria Rosa;
Fernández, Maria del Mar;
Gonzalo-Flores, Sandra;
Villar-Rodil, Silvia;
San Román, Julio;
Pişkin, Erhan

Publication type:

Article

Preparation and in vitro percutaneous penetration of simvastatin ethosome gel.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2013, v. 41, n. 5, p. 315, doi. 10.3109/10731199.2012.743903

By:

An, Keyao;
Sun, Yong;
Wu, Yan;
Yuan, Haicheng;
Cui, Zhaoyuan;
Xu, Lisa

Publication type:

Article

EXPLORING LIPID LOWERING ACTIVITY OF CASSIA FISTULA AND SIMVASTATIN, IN HYPERLIPIDEMIC MICE.

Published in:

Journal of University Medical & Dental College, 2019, v. 10, n. 2, p. 1

By:

Nawaz, Usman;
Ilyas, Nasim;
Ali, Hussain

Publication type:

Article

Comparison of lipid profile improvements with low dose of rosuvastatin and simvastatin as lipid lowering drugs in high risk patients: A randomized clinical trial.

Published in:

Isra Medical Journal, 2019, v. 11, n. 3, p. 141

By:

Ilahi, Anjum;
Khan, Adnan Saleem;
Zainab, Sadia;
Ilahi, Mansur

Publication type:

Article

A Novel Stability Study of Simvastatin Generic Tablet in Public Pharmacy Facilities of Purwakarta, Indonesia.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2021, v. 32, n. 4, p. 548

By:

Yulianita, Rini;
Sopyan, Iyan;
Gazzali, Amirah Mohd;
Muchtaridi, Muchtaridi

Publication type:

Article

Comparative Study of Betulinic Acid Versus Simvastatin on Total Cholesterol and HDL in Hyperlipidemic Model.

Published in:

Biomedica, 2018, v. 34, n. 4, p. 248

By:

A., Zainub;
F., Ayub;
A., Jehangir;
T., Inam;
S., Lodhi;
S., Ayub

Publication type:

Article

Pharmacokinetics and Bioequivalence of Fixed‐Dose Combination of Simvastatin and Ezetimibe Tablets: A Randomized, Crossover, Open‐Label Study in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2024, v. 13, n. 8, p. 938, doi. 10.1002/cpdd.1411

By:

Leong, Chuei Wuei;
Yee, Kar Ming;
Rani, Tracy Ann;
Lau, Kheng Jinm;
Ahmad, Shahnun;
Amran, Atiqah;
Mohd Hassan, Farah Wahidah;
Kumar, Naveen

Publication type:

Article

Effect of Roxadustat on the Pharmacokinetics of Simvastatin, Rosuvastatin, and Atorvastatin in Healthy Subjects: Results From 3 Phase 1, Open‐Label, 1‐Sequence, Crossover Studies.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 4, p. 486, doi. 10.1002/cpdd.1076

By:

Groenendaal‐van de Meent, Dorien;
den Adel, Martin;
Kerbusch, Virginie;
van Dijk, Jan;
Shibata, Tomohisa;
Kato, Kota;
Schaddelee, Marloes

Publication type:

Article

Assessment of the Drug Interaction Potential of Ertugliflozin With Sitagliptin, Metformin, Glimepiride, or Simvastatin in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2019, v. 8, n. 3, p. 314, doi. 10.1002/cpdd.472

By:

Dawra, Vikas Kumar;
Cutler, David L.;
Zhou, Susan;
Krishna, Rajesh;
Shi, Haihong;
Liang, Yali;
Alvey, Christine;
Hickman, Anne;
Saur, Didier;
Terra, Steven G.;
Sahasrabudhe, Vaishali

Publication type:

Article

Effect of canagliflozin on the pharmacokinetics of glyburide, metformin, and simvastatin in healthy participants.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 3, p. 226, doi. 10.1002/cpdd.166

By:

Devineni, Damayanthi;
Manitpisitkul, Prasarn;
Murphy, Joseph;
Skee, Donna;
Wajs, Ewa;
Mamidi, Rao N. V. S.;
Tian, Hong;
Vandebosch, An;
Wang, Shean-Sheng;
Verhaeghe, Tom;
Stieltjes, Hans;
Usiskin, Keith

Publication type:

Article

Exploring New Zealand prescription data using sequence symmetry analyses for predicting adverse drug reactions.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2017, v. 42, n. 2, p. 189, doi. 10.1111/jcpt.12491

By:

Nishtala, P. S.;
Chyou, T.‐y.

Publication type:

Article

Simvastatin monotherapy as a potential option for statin-associated muscle symptoms: a case report.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2016, v. 41, n. 5, p. 568, doi. 10.1111/jcpt.12419

By:

Qu, H.;
Guo, M.;
Kou, N.;
Wu, H.‐t.;
Zhang, Y.;
Gao, Z.‐y.;
Shi, D.‐z.

Publication type:

Article

In vitro and clinical evaluation of OATP-mediated drug interaction potential of sacubitril/valsartan ( LCZ696).

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2016, v. 41, n. 4, p. 424, doi. 10.1111/jcpt.12408

By:

Ayalasomayajula, S.;
Han, Y.;
Langenickel, T.;
Malcolm, K.;
Zhou, W.;
Hanna, I.;
Alexander, N.;
Natrillo, A.;
Goswami, B.;
Hinder, M.;
Sunkara, G.

Publication type:

Article

Systematic review of red yeast rice compared with simvastatin in dyslipidaemia.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2016, v. 41, n. 2, p. 170, doi. 10.1111/jcpt.12374

By:

Ong, Yi Chin;
Aziz, Zoriah

Publication type:

Article

The prevalence of co-prescription of clinically relevant CYP enzyme inhibitor and substrate drugs in community-dwelling elderly Australians.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2014, v. 39, n. 4, p. 383, doi. 10.1111/jcpt.12163

By:

Kerr, K. P.;
Mate, K. E.;
Magin, P. J.;
Marley, J.;
Stocks, N. P.;
Disler, P.;
Pond, C. D.

Publication type:

Article

Simvastatin and amlodipine induced thrombocytopenia in the same patient: double trouble and a literature review.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2013, v. 38, n. 3, p. 246, doi. 10.1111/jcpt.12051

By:

Cvetković, Zorica;
Suvajdžić‐Vuković, Nada;
Todorović, Zoran;
Panić, Miloš;
Nešković, Aleksandar

Publication type:

Article

Impact of out-of-pocket expenses on discontinuation of statin therapy: a cohort study in Finland.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2012, v. 37, n. 1, p. 58, doi. 10.1111/j.1365-2710.2011.01250.x

By:

Helin-Salmivaara, A.;
Korhonen, M.J.;
Alanen, T.;
Huupponen, R.

Publication type:

Article

Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1550133

By:

Zanichelli, Andrea;
Cattaneo, Dario;
Gidaro, Antonio;
Senter, Riccardo;
Arcoleo, Francesco;
Accardo, Pietro;
Bignardi, Donatella;
Borrelli, Paolo;
Colangelo, Caterina;
De Pasquale, Tiziana;
Firinu, Davide;
Perego, Francesca;
Triggiani, Massimo;
Spadaro, Giuseppe;
Cogliati, Chiara;
Bizzi, Emanuele;
Popescu Janu, Valentina;
Guarino, Maria Domenica;
Quattrocchi, Paolina;
Brussino, Luisa

Publication type:

Article

Simvastatin Enhances Activity and Trafficking of α7 Nicotinic Acetylcholine Receptor in Hippocampal Neurons Through PKC and CaMKII Signaling Pathways.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00362

By:

Chen, Tingting;
Wang, Ya;
Zhang, Tingting;
Zhang, Baofeng;
Chen, Lei;
Zhao, Liandong;
Chen, Ling

Publication type:

Article

Simvastatin Therapy for Drug Repositioning to Reduce the Risk of Prostate Cancer Mortality in Patients With Hyperlipidemia.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00225

By:

Chen, Yu-An;
Lin, Ying-Ju;
Lin, Cheng-Li;
Lin, Hwai-Jeng;
Wu, Hua-Shan;
Hsu, Hui-Ying;
Sun, Yu-Chen;
Wu, Hui-Yu;
Lai, Chih-Ho;
Kao, Chia-Hung

Publication type:

Article

Effects of Simvastatin Beyond Dyslipidemia: Exploring Its Antinociceptive Action in an Animal Model of Complex Regional Pain Syndrome-Type I.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00584

By:

Vieira, Graziela;
Cavalli, Juliana;
Gonçalves, Elaine C. D.;
Gonçalves, Tainara R.;
Laurindo, Larissa R.;
Cola, Maíra;
Dutra, Rafael C.

Publication type:

Article