Works about SILIBININ

Results: 242

Explaining Uncertain Hepatoprotective Effects: When Silibinin Co-Administered with Other Drugs.

Published in:

Medeniyet Medical Journal, 2025, v. 40, n. 2, p. 37, doi. 10.4274/MMJ.galenos.2025.71163

By:

Dong Pu;
Qinwei SUN;
Zengxiang ZHAO;
Sisi WANG;
Ji LI;
Feng YU

Publication type:

Article

Explaining Uncertain Hepatoprotective Effects: When Silibinin Co-Administered with Other Drugs.

Published in:

Medeniyet Medical Journal, 2025, v. 40, n. 2, p. 37, doi. 10.4274/MMJ.galenos.2025.71163

By:

Dong Pu;
Qinwei SUN;
Zengxiang ZHAO;
Sisi WANG;
Ji LI;
Feng YU

Publication type:

Article

Sustained virological response with intravenous silibinin: individualized IFN-free therapy via real-time modelling of HCV kinetics.

Published in:

Liver International, 2015, v. 35, n. 2, p. 289, doi. 10.1111/liv.12692

By:

Dahari, Harel;
Shteingart, Shimon;
Gafanovich, Inna;
Cotler, Scott J.;
D'Amato, Massimo;
Pohl, Ralf T.;
Weiss, Gali;
Ashkenazi, Yaakov J.;
Tichler, Thomas;
Goldin, Eran;
Lurie, Yoav

Publication type:

Article

The therapeutic effect of silibinin against 5‐fluorouracil‐induced ovarian toxicity in rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 9, p. 1, doi. 10.1002/jbt.23408

By:

Ayazoglu Demir, Elif;
Mentese, Ahmet;
Kucuk, Hatice;
Turkmen Alemdar, Nihal;
Demir, Selim

Publication type:

Article

Synthesis of New Silybin Derivatives and Evaluation of Their Antioxidant Properties.

Published in:

Helvetica Chimica Acta, 2015, v. 98, n. 3, p. 399, doi. 10.1002/hlca.201400282

By:

Romanucci, Valeria;
Di Fabio, Giovanni;
Zarrelli, Armando;
De Napoli, Lorenzo;
Previtera, Lucio

Publication type:

Article

Ribose Mediated Glycation of Human Serum Albumin and Their Inhibition by Silibinin and 2-Hydroxy-1,4-Naphthoquinone: In Vitro and Computational Studies.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 7, p. 965, doi. 10.1142/S273741652550005X

By:

Elrobh, Mohamed;
Khan, Mohd Shahnawaz;
Alenad, Amal;
Alokail, Majed S.;
Alharbi, Osama M.;
Odeibat, Hamza Ahmad

Publication type:

Article

Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 6, p. 1770, doi. 10.3390/jcm9061770

By:

Bosch-Barrera, Joaquim;
Martin-Castillo, Begoña;
Buxó, Maria;
Brunet, Joan;
Encinar, José Antonio;
Menendez, Javier A.

Publication type:

Article

Silibinin Suppresses Inflammatory Responses Induced by Exposure to Asian Sand Dust.

Published in:

Antioxidants, 2024, v. 13, n. 10, p. 1187, doi. 10.3390/antiox13101187

By:

Lee, Se-Jin;
Pak, So-Won;
Kim, Woong-Il;
Park, Sin-Hyang;
Cho, Young-Kwon;
Ko, Je-Won;
Kim, Tae-Won;
Kim, Joong-Sun;
Kim, Jong-Choon;
Lim, Je-Oh;
Shin, In-Sik

Publication type:

Article

Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries.

Published in:

Antioxidants, 2023, v. 12, n. 12, p. 2119, doi. 10.3390/antiox12122119

By:

Duan, Wentao;
Ou, Zexian;
Huang, Yuxing;
Zhang, Yifan;
Zhang, Lan;
Zhao, Yanan;
He, Ruikun;
Zhang, Yihan;
Ge, Yuanlong;
Lou, Huiling;
Ju, Zhenyu;
Hu, Qian

Publication type:

Article

Enhancement of anticancer activity by silibinin and paclitaxel combination on the ovarian cancer.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, n. 7, p. 1483, doi. 10.1080/21691401.2017.1374281

By:

Pashaei-Asl, Fatima;
Pashaei-Asl, Roghiyeh;
Khodadadi, Khodadad;
Akbarzadeh, Abolfazl;
Ebrahimie, Esmaeil;
Pashaiasl, Maryam

Publication type:

Article

Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, n. 3, p. 524, doi. 10.1080/21691401.2017.1326928

By:

Yazdi Rouholamini, Seyede Elmira;
Moghassemi, Saeid;
Maharat, Zahra;
Hakamivala, Amirhossien;
Kashanian, Susan;
Omidfar, Kobra

Publication type:

Article

Silibinin-loaded magnetic nanoparticles inhibit hTERT gene expression and proliferation of lung cancer cells.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2017, v. 45, n. 8, p. 1649, doi. 10.1080/21691401.2016.1276922

By:

Amirsaadat, Soumaye;
Pilehvar-Soltanahmadi, Younes;
Zarghami, Faraz;
Alipour, Shahriar;
Ebrahimnezhad, Zohreh;
Zarghami, Nosratollah

Publication type:

Article

Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00021

By:

Hou, Xiaoying;
Du, Hongzhi;
Quan, Xingping;
Shi, Lei;
Zhang, Qianqian;
Wu, Yao;
Liu, Yang;
Xiao, Jing;
Li, Yong;
Lu, Ligong;
Ai, Xun;
Zhan, Meixiao;
Yuan, Shengtao;
Sun, Li

Publication type:

Article

Silibinin: A New Opportunity for the Treatment of Brain Metastasis from Lung Cancer.

Published in:

Journal of Experimental Pharmacology, 2021, v. 13, p. 901, doi. 10.2147/JEP.S326871

By:

Addeo, Raffaele

Publication type:

Article

Antimicrobial Efficacy of Silymarin and Silibinin Against Oral Microorganisms.

Published in:

Journal of Microbiology & Infectious Diseases, 2017, v. 7, n. 3, p. 139, doi. 10.5799/jmid.367545

By:

Iyangar Radhika, Murali;
Ezhilarasan, Devaraj;
Gopinath, Prakasam

Publication type:

Article

Silibinin improves nonalcoholic fatty liver by regulating the expression of miR-122: An in vitro and in vivo study.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 5, p. N.PAG, doi. 10.3892/mmr.2021.11974

By:

Yang, Liying;
Liu, Qianqian;
Zhang, He;
Wang, Yichao;
Li, Yang;
Chen, Shuchun;
Song, Guangyao;
Ren, Luping

Publication type:

Article

Silibinin A decreases statin-induced PCSK9 expression in human hepatoblastoma HepG2 cells.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 2, p. 1383, doi. 10.3892/mmr.2019.10344

By:

Dong, Zhewen;
Zhang, Wenxiang;
Chen, Siyu;
Liu, Chang

Publication type:

Article

Synergistic apoptotic effects of silibinin in enhancing paclitaxel toxicity in human gastric cancer cell lines.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 1835, doi. 10.3892/mmr.2018.9129

By:

Zhang, Yuanxin;
Ge, Yakun;
Ping, Xie;
Yu, Ming;
Lou, Dawei;
Shi, Wei

Publication type:

Article

Anti-proliferative activity of epigallocatechin-3-gallate and silibinin on soft tissue sarcoma cells.

Published in:

Molecular Medicine Reports, 2017, v. 15, n. 1, p. 103, doi. 10.3892/mmr.2016.5969

By:

HARATI, KAMRAN;
BEHR, BJÖRN;
WALLNER, CHRISTOPH;
DAIGELER, ADRIEN;
HIRSCH, TOBIAS;
JACOBSEN, FRANK;
RENNER, MARCUS;
HARATI, ALI;
LEHNHARDT, MARCUS;
BECERIKLI, MUSTAFA

Publication type:

Article

The Milk Thistle (Silybum marianum) Compound Silibinin Inhibits Cardiomyogenesis of Embryonic Stem Cells by Interfering with Angiotensin II Signaling.

Published in:

Stem Cells International, 2018, p. 1, doi. 10.1155/2018/9215792

By:

Ali, Enas Hussein;
Sharifpanah, Fatemeh;
Taha, Amer;
Tsang, Suk Ying;
Wartenberg, Maria;
Sauer, Heinrich

Publication type:

Article

Jiangzhi Paizhuo Decoction Combined with Silibinin Capsules Improve the Outcomes of Metabolic Associated Fatty Liver Disease.

Published in:

Natural Product Communications, 2024, v. 19, n. 8, p. 1, doi. 10.1177/1934578X241274900

By:

Jianmei Hao;
Yuanjing Xie;
Zhiping Yang;
Jianwei Dou;
Minghua Mao;
Xiaofang Li

Publication type:

Article

Lung cancer targeting efficiency of Silibinin loaded Poly Caprolactone /Pluronic F68 Inhalable nanoparticles: In vitro and In vivo study.

Published in:

PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0267257

By:

Patel, Priya;
Raval, Mihir;
Manvar, Aneka;
Airao, Vishal;
Bhatt, Vaibhav;
Shah, Pranav

Publication type:

Article

Silibinin alleviates inflammation‐induced bone loss by modulating biological interaction between human gingival fibroblasts and monocytes.

Published in:

Journal of Periodontology, 2023, v. 94, n. 7, p. 905, doi. 10.1002/JPER.22-0535

By:

Huang, Ren‐Yeong;
Chang, Hua‐Yang;
Chih, Shu‐Mi;
Dyke, Thomas Van;
Cheng, Chia‐Dan;
Sung, Cheng‐En;
Weng, Pei‐Wei;
Shieh, Yi‐Shing;
Cheng, Wan‐Chien

Publication type:

Article

Physiological and Histological Study of the Therapeutic Effect of Silibinin on Testicular Alteration in Adult Male Albino Rats.

Published in:

Indian Journal of Pharmaceutical Sciences, 2023, v. 85, p. 1

By:

MELEBARY, SAHAR J.

Publication type:

Article

Silibinin: a toxicologist's herbal medicine?

Published in:

Clinical Toxicology (15563650), 2022, v. 60, n. 11, p. 1194, doi. 10.1080/15563650.2022.2128815

By:

Zane Horowitz, B.

Publication type:

Article

Investigation and analysis of <italic>Galerina sulciceps</italic> poisoning in a canteen.

Published in:

Clinical Toxicology (15563650), 2018, v. 56, n. 5, p. 365, doi. 10.1080/15563650.2017.1388386

By:

Xiang, Hong;
Zhou, Yajuan;
Zhou, Changlin;
Lei, Shiguang;
Yu, Hong;
Wang, Yafang;
Zhu, Shu

Publication type:

Article

A new tetracyclic saponin from Astragalus glycyphyllos L. and its neuroprotective and hMAO-B inhibiting activity.

Published in:

Natural Product Research, 2020, v. 34, n. 4, p. 511, doi. 10.1080/14786419.2018.1491040

By:

Shkondrov, Aleksandar;
Krasteva, Ilina;
Bucar, Franz;
Kunert, Olaf;
Kondeva-Burdina, Magdalena;
Ionkovaa, Iliana

Publication type:

Article

Polyamido amine (PAMAM)-grafted magnetic nanotubes as emerging platforms for the delivery and sustained release of silibinin.

Published in:

Journal of Materials Science, 2017, v. 52, n. 16, p. 9269, doi. 10.1007/s10853-017-1140-4

By:

Chávez, Gloria;
Campos, Cristian;
Jiménez, Verónica;
Torres, Cecilia;
Díaz, Carola;
Salas, Gorka;
Guzmán, Leonardo;
Alderete, Joel

Publication type:

Article

Isolation and characterization of iron chelators from turmeric ( Curcuma longa): selective metal binding by curcuminoids.

Published in:

BioMetals, 2017, v. 30, n. 5, p. 699, doi. 10.1007/s10534-017-0038-6

By:

Messner, Donald;
Surrago, Christine;
Fiordalisi, Celia;
Chung, Wing;
Kowdley, Kris

Publication type:

Article

THE CHARACTERIZATION OF SILYMARIN AND SILIBININ LIPOSOMES.

Published in:

Journal of Engineering & Processing Management, 2023, v. 14, n. 2, p. 40, doi. 10.7251/JEPM2202040j

By:

Jovanović, Aleksandra A.;
Dinić, Svetlana;
Uskoković, Aleksandra;
Arambašić Jovanović, Jelena;
Grdović, Nevena;
Vidaković, Melita;
Mihailović, Mirjana

Publication type:

Article

Effects of silibinin-loaded thermosensitive liposome-microbubble complex on inhibiting rabbit liver VX2 tumors in sub-hyperthermia fields.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 2, p. 1233, doi. 10.3892/etm.2017.5566

By:

Han, Lu;
Guo, Kai;
Gu, Fen;
Zhang, Yun-Fei;
Li, Ke;
Mu, Xi-Xi;
Liu, Hai-Jing;
Zhou, Xiao-Dong;
Luo, Wen

Publication type:

Article

Silibinin attenuates methotrexate-induced pulmonary injury by targeting oxidative stress.

Published in:

Experimental & Therapeutic Medicine, 2015, v. 10, n. 2, p. 503, doi. 10.3892/etm.2015.2542

By:

KALEMCI, SERDAR;
TOPAL, YASAR;
CELIK, SERKAN YASAR;
YILMAZ, NIGAR;
ALTUNTAS, IRFAN;
BEYDILLI, HALIL;
KOSAR, MEHMET ILKAY;
DIRICAN, NIGAR

Publication type:

Article

Silibinin inhibits accumulation of myeloid-derived suppressor cells and tumor growth of murine breast cancer.

Published in:

Cancer Medicine, 2014, v. 3, n. 2, p. 215, doi. 10.1002/cam4.186

By:

Forghani, Parvin;
Khorramizadeh, Mohammad R.;
Waller, Edmund K.

Publication type:

Article

Silibinin Regulates Tumor Progression and Tumorsphere Formation by Suppressing PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 7, p. 1632, doi. 10.3390/cells10071632

By:

Rugamba, Alexis;
Kang, Dong Young;
Sp, Nipin;
Jo, Eun Seong;
Lee, Jin-Moo;
Bae, Se Won;
Jang, Kyoung-Jin

Publication type:

Article

Silibinin Upregulates CXCR4 Expression in Cultured Bone Marrow Cells (BMCs) Especially in Pulmonary Arterial Hypertension Rat Model.

Published in:

Cells (2073-4409), 2020, v. 9, n. 5, p. 1276, doi. 10.3390/cells9051276

By:

Zhang, Tingting;
Kawaguchi, Nanako;
Tsuji, Kunikazu;
Hayama, Emiko;
Furutani, Yoshiyuki;
Sugiyama, Hisashi;
Nakanishi, Toshio

Publication type:

Article

Silibinin Attenuates Silica Dioxide Nanoparticles-Induced Inflammation by Suppressing TXNIP/MAPKs/AP-1 Signaling.

Published in:

Cells (2073-4409), 2020, v. 9, n. 3, p. 678, doi. 10.3390/cells9030678

By:

Lim, Je-Oh;
Shin, Na-Rae;
Seo, Yun-Soo;
Nam, Hyeon-Hwa;
Ko, Je-Won;
Jung, Tae-Yang;
Lee, Se-Jin;
Kim, Ha-Jung;
Cho, Young-Kwon;
Kim, Jong-Choon;
Lee, In-Chul;
Kim, Joong-Sun;
Shin, In-Sik

Publication type:

Article

Inhibition of silibinin on migration and adhesion capacity of human highly metastatic breast cancer cell line, MDA-MB-231, by evaluation of β1-integrin and downstream molecules, Cdc42, Raf-1 and D4GDI.

Published in:

Medical Oncology, 2012, v. 29, n. 4, p. 2512, doi. 10.1007/s12032-011-0113-8

By:

Dastpeyman, Mohadeseh;
Motamed, Nasrin;
Azadmanesh, Kayhan;
Mostafavi, Ehsan;
Kia, Vahid;
Jahanian-Najafabadi, Ali;
Shokrgozar, Mohammad

Publication type:

Article

The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells.

Published in:

Human & Experimental Toxicology, 2017, v. 36, n. 6, p. 573, doi. 10.1177/0960327116658105

By:

Bayram, D.;
Çetin, E. S.;
Kara, M.;
Özgöçmen, M.;
Candan, I. A.

Publication type:

Article

Silibinin mitigates zidovudine-induced hepatocellular degenerative changes, oxidative stress and hyperlipidaemia in rats.

Published in:

Human & Experimental Toxicology, 2015, v. 34, n. 11, p. 1031, doi. 10.1177/0960327114567765

By:

Raghu, R.;
Jesudas, B.;
Bhavani, G.;
Ezhilarasan, D.;
Karthikeyan, S.

Publication type:

Article

Role of heat shock protein 70 in silibinin-induced apoptosis in bladder cancer.

Published in:

Journal of Cancer, 2024, v. 15, n. 1, p. 79, doi. 10.7150/jca.88668

By:

Yi Wei;
Yanxin Zhuang;
Yishuai Zhang;
Lei Luo;
Bixin Yu;
Jin Zeng

Publication type:

Article

Silibinin induces oral cancer cell apoptosis and reactive oxygen species generation by activating the JNK/c-Jun pathway.

Published in:

Journal of Cancer, 2023, v. 14, n. 10, p. 1875, doi. 10.7150/jca.84734

By:

Haibo Zhang;
Hyeonjin Kim;
Si-Yong Kim;
Huang Hai;
Eungyung Kim;
Lei Ma;
Dongwook Kim;
Chae Yeon Kim;
Kanghyun Park;
Sijun Park;
Jiwon Ko;
Eun-Kyong Kim;
Kirim Kim;
Zae Young Ryoo;
Junkoo Yi;
Myoung Ok Kim

Publication type:

Article

Silibinin inhibits the migration, invasion and epithelial-mesenchymal transition of prostate cancer by activating the autophagic degradation of YAP.

Published in:

Journal of Cancer, 2022, v. 13, n. 13, p. 3415, doi. 10.7150/jca.63514

By:

Weichao Dan;
Yizeng Fan;
Tao Hou;
Yi Wei;
Bo Liu;
Taotao Que;
Bixin Yu;
Jin Zeng;
Lei Li

Publication type:

Article

Liposome Encapsulation Enhances the Antidiabetic Efficacy of Silibinin.

Published in:

Pharmaceutics, 2024, v. 16, n. 6, p. 801, doi. 10.3390/pharmaceutics16060801

By:

Dinić, Svetlana;
Arambašić Jovanović, Jelena;
Uskoković, Aleksandra;
Jovanović, Aleksandra;
Grdović, Nevena;
Rajić, Jovana;
Đorđević, Marija;
Sarić, Ana;
Bugarski, Branko;
Vidaković, Melita;
Mihailović, Mirjana

Publication type:

Article

Novel Pullulan/Gellan Gum Bilayer Film as a Vehicle for Silibinin-Loaded Nanocapsules in the Topical Treatment of Atopic Dermatitis.

Published in:

Pharmaceutics, 2022, v. 14, n. 11, p. 2352, doi. 10.3390/pharmaceutics14112352

By:

Gehrcke, Mailine;
Martins, Carolina Cristóvão;
de Bastos Brum, Taíne;
da Rosa, Lucas Saldanha;
Luchese, Cristiane;
Wilhelm, Ethel Antunes;
Soares, Fabio Zovico Maxnuck;
Cruz, Letícia

Publication type:

Article

Silibinin's Effects against Methotrexate-Induced Hepatotoxicity in Adjuvant-Induced Arthritis Rat Model.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 431, doi. 10.3390/ph17040431

By:

Khawaja, Ghada;
El-Orfali, Youmna

Publication type:

Article

A Comprehensive Review of the Cardiovascular Protective Properties of Silibinin/Silymarin: A New Kid on the Block.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 538, doi. 10.3390/ph15050538

By:

Kadoglou, Nikolaos P. E.;
Panayiotou, Chrystalla;
Vardas, Michail;
Balaskas, Nikolaos;
Kostomitsopoulos, Nikolaos G.;
Tsaroucha, Alexandra K.;
Valsami, Georgia

Publication type:

Article

Clinical Management of COVID-19 in Cancer Patients with the STAT3 Inhibitor Silibinin.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 1, p. 19, doi. 10.3390/ph15010019

By:

Bosch-Barrera, Joaquim;
Roqué, Ariadna;
Teixidor, Eduard;
Carmona-Garcia, Maria Carmen;
Arbusà, Aina;
Brunet, Joan;
Martin-Castillo, Begoña;
Cuyàs, Elisabet;
Verdura, Sara;
Menendez, Javier A.

Publication type:

Article

Lung Cancer Management with Silibinin: A Historical and Translational Perspective.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 6, p. 559, doi. 10.3390/ph14060559

By:

Verdura, Sara;
Cuyàs, Elisabet;
Ruiz-Torres, Verónica;
Micol, Vicente;
Joven, Jorge;
Bosch-Barrera, Joaquim;
Menendez, Javier A.

Publication type:

Article

Silibinin and colorectal cancer chemoprevention: a comprehensive review on mechanisms and efficacy.

Published in:

Journal of Biomedical Research, 2016, v. 30, n. 6, p. 452, doi. 10.7555/JBR.30.20150111

By:

Raina, Komal;
Kumar, Sushil;
Dhar, Deepanshi;
Agarwal, Rajesh

Publication type:

Article

Silibinin inhibits myofibroblast transdifferentiation in human tenon fibroblasts and reduces fibrosis in a rabbit trabeculectomy model.

Published in:

Acta Ophthalmologica (1755375X), 2013, v. 91, n. 7, p. e506, doi. 10.1111/aos.12160

By:

Chen, Yi‐Hao;
Liang, Chang‐Min;
Chen, Ching‐Long;
Chen, Jiann‐Torng;
Chang, Yun‐Hsiang;
Lu, Da‐Wen;
Chien, Ke‐Hung;
Tai, Ming‐Cheng

Publication type:

Article