Works about SILIBININ

Results: 238

Ribose Mediated Glycation of Human Serum Albumin and Their Inhibition by Silibinin and 2-Hydroxy-1,4-Naphthoquinone: In Vitro and Computational Studies.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 7, p. 965, doi. 10.1142/S273741652550005X

By:

Elrobh, Mohamed;
Khan, Mohd Shahnawaz;
Alenad, Amal;
Alokail, Majed S.;
Alharbi, Osama M.;
Odeibat, Hamza Ahmad

Publication type:

Article

Anxiolytic effects of silibinin and naringenin on zebrafish model: A preclinical study.

Published in:

Indian Journal of Pharmacology, 2021, v. 53, n. 6, p. 457, doi. 10.4103/ijp.IJP_18_20

By:

Nachammai, V;
Jeyabalan, Srikanth;
Muthusamy, Sivakumar

Publication type:

Article

POSTER PAPERS.

Published in:: 2014
Publication type:: Abstract

Spectroscopic analysis, NBO, HOMO and LUMO analysis of anticancer compound Silibinin: experimental and theoretical approach.

Published in:

Materials Research Innovations, 2023, v. 27, n. 1, p. 1, doi. 10.1080/14328917.2022.2043648

By:

Sundari, S;
Arumugam, Muthuraja;
Chandra, S.

Publication type:

Article

The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 9, p. 1274, doi. 10.1093/jpp/rgab062

By:

Betsou, Afrodite;
Lambropoulou, Maria;
Georgakopoulou, Anastasia-Eirini;
Kostomitsopoulos, Nikolaos;
Konstandi, Ourania;
Anagnostopoulos, Konstantinos;
Tsalikidis, Christos;
Simopoulos, Constantinos E.;
Valsami, Georgia;
Tsaroucha, Alexandra K.

Publication type:

Article

In-vitro stability and metabolism of a tacrine-silibinin codrug.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 12, p. 1765, doi. 10.1111/jphp.12070

By:

Zenger, Katharina;
Chen, Xinyu;
Decker, Michael;
Kraus, Birgit

Publication type:

Article

Silibinin Induces Apoptosis and G2/M Cell Cycle Arrest in Human Ovarian Cancer SKOV-3 Cell Line.

Published in:

Jentashapir Journal of Cellular & Molecular Biology, 2023, v. 14, n. 3, p. 1, doi. 10.5812/jjcmb-136980

By:

Sadriforoush, Sahar Baghal;
Jahanafrooz, Zohreh;
Motamed, Nasrin

Publication type:

Article

Silibinin: An Inhibitor of Mir-181a Gene Expression in Sk-Br-3 Breast Cancer Cell Line.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2018, v. 52, n. 3, p. 597, doi. 10.5530/ijper.51.4.89

By:

Shahinfar, Parvaneh;
Motamed, Nasrin;
Birjandian, Elnaz;
Shabanpour, Omid

Publication type:

Article

Silibinin: An Inhibitor of Mir-181a Gene Expression in Sk-Br-3 Breast Cancer Cell Line.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2017, v. 51, n. 4, p. 597, doi. 10.5530/ijper.51.4.89

By:

Shahinfar, Parvaneh;
Motamed, Nasrin;
Birjandian, Elnaz;
Shabanpour, Omid

Publication type:

Article

Silibinin ameliorates the cardiovascular oxidative and inflammatory effects of type-2-diabetic rats exposed to air particulate matter.

Published in:

Polycyclic Aromatic Compounds, 2023, v. 43, n. 7, p. 6570, doi. 10.1080/10406638.2022.2123536

By:

Awolaja, Olamide O.;
Lawal, Akeem O.;
Folorunso, Ibukun M.;
Elekofehinti, Olusola O.;
Umar, Haruna I.

Publication type:

Article

Silibinin attenuates oxidative metabolism and cytokine production by monocytes from preeclamptic women.

Published in:

Free Radical Research, 2013, v. 47, n. 4, p. 268, doi. 10.3109/10715762.2013.765951

By:

Cristofalo, R.;
Bannwart-Castro, C. F.;
Magalhães, C. G.;
Borges, V. T. M.;
Peraçoli, J. C.;
Witkin, S. S.;
Peraçoli, M. T.

Publication type:

Article

Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells.

Published in:

Free Radical Research, 2012, v. 46, n. 11, p. 1346, doi. 10.3109/10715762.2012.715369

By:

Yu, Yang;
Fan, Si Miao;
Yuan, Su Juan;
Tashiro, Shin-Ichi;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells.

Published in:

Free Radical Research, 2012, v. 46, n. 9, p. 1082, doi. 10.3109/10715762.2012.688964

By:

Fan, Simiao;
Yu, Yang;
Qi, Min;
Sun, Zhongdong;
Li, Lihua;
Yao, Guodong;
Tashiro, Shin-Ichi;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.

Published in:

Free Radical Research, 2012, v. 46, n. 3, p. 310, doi. 10.3109/10715762.2012.655244

By:

Fan, Simiao;
Qi, Min;
Yu, Yang;
Li, Lihua;
Yao, Guodong;
Tashiro, Shin-Ichi;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells.

Published in:

Free Radical Research, 2010, v. 44, n. 1, p. 90, doi. 10.3109/10715760903300717

By:

Wang, Hong-Jun;
Jiang, Yuan-Yuan;
Wei, Xiao-Feng;
Huang, Huai;
Tashiro, Shin-Ichi;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

Polyamidoamine dendrimer-mediated hydrogel for solubility enhancement and anti-cancer drug delivery.

Published in:

Journal of Biomaterials Applications, 2024, v. 38, n. 6, p. 733, doi. 10.1177/08853282231213712

By:

Bi, Xiangdong;
Watts, Darra B;
Dorman, Ian;
Kirk, Casianna M;
Thomas, Marisa;
Singleton, Isaiah;
Malcom, Colleen;
Barnes, Taylor;
Carter, Colby;
Liang, Aiye

Publication type:

Article

Silibinin augments the effect of clopidogrel on atherosclerosis in diabetic ApoE deficiency mice.

Published in:

Clinical Hemorheology & Microcirculation, 2022, v. 80, n. 4, p. 353, doi. 10.3233/CH-211279

By:

Zhang, Jianbo;
Shi, Qiyu;
Hu, Yamin;
Li, Xiaohong

Publication type:

Article

Silibinin ameliorates hyperglycaemia, hyperlipidemia and prevent oxidative stress in streptozotocin induced diabetes in Sprague Dawley rats.

Published in:

International Journal of Pharmaceutical Research & Allied Sciences, 2016, v. 5, n. 3, p. 136

By:

Jain, Dilpesh;
Somani, Rahul;
Gilhotra, Ritu

Publication type:

Article

A comprehensive evaluation of the therapeutic potential of silibinin: a ray of hope in cancer treatment.

Published in:

Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1349745

By:

Ray, Pantha Prodip;
Islam, Mohammad Ashraful;
Islam, Mohammad Safiqul;
Han, Aixia;
Geng, Peiwu;
Aziz, Md. Abdul;
Al Mamun, Abdullah

Publication type:

Article

Silibinin alleviates intestinal inflammation via inhibiting JNK signaling in Drosophila.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1246960

By:

La Yan;
Juanyu Zhou;
Lu Yuan;
Jinbao Ye;
Xudong Zhao;
Gang Ren;
Haiyang Chen

Publication type:

Article

Targeted delivery of silibinin via magnetic niosomal nanoparticles: potential application in treatment of colon cancer cells.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1174120

By:

Shafie, Golchin;
Jafari-Gharabaghlou, Davoud;
Farhoudi-Sefidan-Jadid, Mahdi;
Alizadeh, Effat;
Fathi, Marziyeh;
Zarghami, Nosratollah

Publication type:

Article

The Natural Agonist of Estrogen Receptor β Silibinin Plays an Immunosuppressive Role Representing a Potential Therapeutic Tool in Rheumatoid Arthritis.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01903

By:

Dupuis, Maria Luisa;
Conti, Fabrizio;
Maselli, Angela;
Pagano, Maria Teresa;
Ruggieri, Anna;
Anticoli, Simona;
Fragale, Alessandra;
Gabriele, Lucia;
Gagliardi, Maria Cristina;
Sanchez, Massimo;
Ceccarelli, Fulvia;
Alessandri, Cristiano;
Valesini, Guido;
Ortona, Elena;
Pierdominici, Marina

Publication type:

Article

Silibinin inhibits hepatitis C virus entry into hepatocytes by hindering clathrin-dependent trafficking.

Published in:

Cellular Microbiology, 2013, v. 15, n. 11, p. 1866, doi. 10.1111/cmi.12155

By:

Blaising, Julie;
Lévy, Pierre L.;
Gondeau, Claire;
Phelip, Capucine;
Varbanov, Mihayl;
Teissier, Elodie;
Ruggiero, Florence;
Polyak, Stephen J.;
Oberlies, Nicholas H.;
Ivanovic, Tijana;
Boulant, Steeve;
Pécheur, Eve‐Isabelle

Publication type:

Article

Bioavailability Following Oral Administration of a Silibinin-Phosphatidylcholine Complex in Cats.

Published in:

International Journal of Applied Research in Veterinary Medicine, 2012, v. 10, n. 2, p. 107

By:

Webb, Craig B.;
Gustafson, Daniel L.;
Twedt, David C.

Publication type:

Article

Behavioral and neurochemical deficits in aging rats with increased neonatal iron intake: silibinin's neuroprotection by maintaining redox balance.

Published in:

Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00206

By:

Hanqing Chen;
Xijin Wang;
Meihua Wang;
Liu Yang;
Zhiqiang Yan;
Yuhong Zhang;
Zhenguo Liu

Publication type:

Article

Silibinin loaded inhalable solid lipid nanoparticles for lung targeting.

Published in:

Journal of Microencapsulation, 2022, v. 39, n. 1, p. 1, doi. 10.1080/02652048.2021.2002448

By:

Patel, Priya;
Raval, Mihir;
Airao, Vishal;
Bhatt, Vaibhav;
Shah, Pranav

Publication type:

Article

Cell-Type-Specific Effects of Silibinin on Vitamin D-Induced Differentiation of AcuteMyeloid Leukemia Cells Are Associated with Differential Modulation of RXRa Levels.

Published in:

Leukemia Research & Treatment, 2012, p. 1, doi. 10.1155/2012/401784

By:

Wassermann, Rina;
Novik, Victoria;
Danilenko, Michael

Publication type:

Article

Enhancement of bioavailability and hepatoprotection by silibinin through conversion to nanoparticles prepared by liquid antisolvent method.

Published in:

Arabian Journal of Chemistry, 2020, v. 13, n. 2, p. 3682, doi. 10.1016/j.arabjc.2020.01.002

By:

Sahibzada, Muhammad Umar Khayam;
Sadiq, Abdul;
Zahoor, Muhammad;
Naz, Sumera;
Shahid, Muhammad;
Qureshi, Najam Afaq

Publication type:

Article

Developing a high-performance liquid chromatography fast and accurate method for quantification of silibinin.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. 1, doi. 10.1186/s13104-019-4774-2

By:

Bakhshi, Faezeh;
Molavi, Ommoleila;
Rashidi, Mohammad Reza;
Shayanfar, Ali;
Amini, Hassan

Publication type:

Article

Milk Thistle and Its Derivative Compounds: A Review of Opportunities for Treatment of Liver Disease.

Published in:

Journal of Veterinary Internal Medicine, 2013, v. 27, n. 1, p. 10, doi. 10.1111/jvim.12002

By:

Hackett, E.S.;
Twedt, D.C.;
Gustafson, D.L.

Publication type:

Article

Silibinin alleviates inflammation‐induced bone loss by modulating biological interaction between human gingival fibroblasts and monocytes.

Published in:

Journal of Periodontology, 2023, v. 94, n. 7, p. 905, doi. 10.1002/JPER.22-0535

By:

Huang, Ren‐Yeong;
Chang, Hua‐Yang;
Chih, Shu‐Mi;
Dyke, Thomas Van;
Cheng, Chia‐Dan;
Sung, Cheng‐En;
Weng, Pei‐Wei;
Shieh, Yi‐Shing;
Cheng, Wan‐Chien

Publication type:

Article

Oral Administration of Silibinin Ameliorates Cognitive Deficits of Parkinson's Disease Mouse Model by Restoring Mitochondrial Disorders in Hippocampus.

Published in:

Neurochemical Research, 2021, v. 46, n. 9, p. 2317, doi. 10.1007/s11064-021-03363-5

By:

Liu, Xiumin;
Wang, Chenkang;
Liu, Weiwei;
Song, Siaoyu;
Fu, Jianing;
Hayashi, Toshihiko;
Mizuno, Kazunori;
Hattori, Shunji;
Fujisaki, Hitomi;
Ikejima, Takashi

Publication type:

Article

Silibinin Alleviates the Learning and Memory Defects in Overtrained Rats Accompanying Reduced Neuronal Apoptosis and Senescence.

Published in:

Neurochemical Research, 2019, v. 44, n. 8, p. 1818, doi. 10.1007/s11064-019-02816-2

By:

Liu, Bo;
Liu, Weiwei;
Liu, Panwen;
Liu, Xiumin;
Song, Xiaoyu;
Hayashi, Toshihiko;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

Estrogen Receptors Are Involved in the Neuroprotective Effect of Silibinin in Aβ<sub>1-42</sub>-Treated Rats.

Published in:

Neurochemical Research, 2018, v. 43, n. 4, p. 796, doi. 10.1007/s11064-018-2481-3

By:

Song, Xiaoyu;
Liu, Bo;
Cui, Lingyu;
Zhou, Biao;
Liu, Lu;
Liu, Weiwei;
Yao, Guodong;
Xia, Mingyu;
Hayashi, Toshihiko;
Hattori, Shunji;
Ushiki-Kaku, Yuko;
Tashiro, Shin-ichi;
Ikejima, Takashi

Publication type:

Article

Antioxidative and Anti-Apoptotic Roles of Silibinin in Reversing Learning and Memory Deficits in APP/PS1 Mice.

Published in:

Neurochemical Research, 2017, v. 42, n. 12, p. 3439, doi. 10.1007/s11064-017-2389-3

By:

Bai, Dafeng;
Jin, Ge;
Yin, Shiliang;
Zou, Dan;
Zhu, Qiwen;
Yang, Zhihang;
Liu, Xuan;
Ren, Lizheng;
Sun, Yifeng;
Gan, Shiming

Publication type:

Article

Protective Effect of Silibinin on Learning and Memory Impairment in LPS-Treated Rats via ROS-BDNF-TrkB Pathway.

Published in:

Neurochemical Research, 2016, v. 41, n. 7, p. 1662, doi. 10.1007/s11064-016-1881-5

By:

Song, Xiaoyu;
Zhou, Biao;
Zhang, Pingping;
Lei, Di;
Wang, Yubin;
Yao, Guodong;
Hayashi, Toshihiko;
Xia, Mingyu;
Tashiro, Shin-ichi;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-κB Expressions May Play an Important Role in Silibinin-Induced Response.

Published in:

Neurochemical Research, 2012, v. 37, n. 9, p. 2053, doi. 10.1007/s11064-012-0827-9

By:

Yousefi, Meysam;
Ghaffari, Seyed;
Soltani, Bahram;
Nafissi, Shahriar;
Momeny, Majid;
Zekri, Ali;
Behmanesh, Mehrdad;
Alimoghaddam, Kamran;
Ghavamzadeh, Ardeshir

Publication type:

Article

Evaluation of the Protective Effect of Silibinin in Rats with Liver Damage Caused by Itraconazole.

Published in:

Cell Biochemistry & Biophysics, 2015, v. 71, n. 2, p. 1215, doi. 10.1007/s12013-014-0331-8

By:

Sozen, Hamdi;
Celik, Ozgür;
Cetin, Esin;
Yilmaz, Nigar;
Aksozek, Alper;
Topal, Yasar;
Cigerci, Ibrahim;
Beydilli, Halil

Publication type:

Article

Effects of silibinin on apoptosis and insulin secretion in rat RINm5F pancreatic β-cells.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 3, p. 201, doi. 10.1080/10520295.2022.2154840

By:

Mazraesefidi, Maryam;
Mahmoodi, Mehdi;
Hajizadeh, Mohammadreza

Publication type:

Article

Silibinin and ellagic acid increase the expression of insulin receptor substrate 1 protein in ultraviolet irradiated rat skin.

Published in:

Biotechnic & Histochemistry, 2020, v. 95, n. 8, p. 641, doi. 10.1080/10520295.2020.1753238

By:

Gorgisen, G.;
Ozkol, H.;
Tuluce, Y.;
Arslan, A.;
Ecer, Y.;
Keskin, S.;
Kaya, Z.;
Ragbetli, M C.

Publication type:

Article

Bio-Actives from Natural Products with Potential Cardioprotective Properties: Isolation, Identification, and Pharmacological Actions of Apigenin, Quercetin, and Silibinin.

Published in:

Molecules, 2023, v. 28, n. 5, p. 2387, doi. 10.3390/molecules28052387

By:

Tomou, Ekaterina-Michaela;
Papakyriakopoulou, Paraskevi;
Skaltsa, Helen;
Valsami, Georgia;
Kadoglou, Nikolaos P. E.

Publication type:

Article

Silibinin and Naringenin against Bisphenol A-Induced Neurotoxicity in Zebrafish Model—Potential Flavonoid Molecules for New Drug Design, Development, and Therapy for Neurological Disorders.

Published in:

Molecules, 2022, v. 27, n. 8, p. N.PAG, doi. 10.3390/molecules27082572

By:

Thayumanavan, Geethanjali;
Jeyabalan, Srikanth;
Fuloria, Shivkanya;
Sekar, Mahendran;
Ravi, Monica;
Selvaraj, Logesh Kumar;
Bala, Logeshwari;
Chidambaram, Kumarappan;
Gan, Siew Hua;
Rani, Nur Najihah Izzati Mat;
Begum, M. Yasmin;
Subramaniyan, Vetriselvan;
Sathasivam, Kathiresan V.;
Meenakshi, Dhanalekshmi U.;
Fuloria, Neeraj Kumar

Publication type:

Article

Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia.

Published in:

Molecules, 2019, v. 24, n. 8, p. 1548, doi. 10.3390/molecules24081548

By:

Matias, Mariana Leticia;
Gomes, Virginia Juliani;
Romao-Veiga, Mariana;
Ribeiro, Vanessa Rocha;
Nunes, Priscila Rezeck;
Romagnoli, Graziela Gorete;
Peracoli, Jose Carlos;
Peracoli, Maria Terezinha Serrao

Publication type:

Article

O-Aminoalkyl-O-Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells.

Published in:

Molecules, 2018, v. 23, n. 12, p. 3142, doi. 10.3390/molecules23123142

By:

Vue, Bao;
Zhang, Sheng;
Vignau, Andre;
Chen, Guanglin;
Zhang, Xiaojie;
Diaz, William;
Zhang, Qiang;
Zheng, Shilong;
Wang, Guangdi;
Chen, Qiao-Hong

Publication type:

Article

Phosphate-Linked Silibinin Dimers (PLSd): New Promising Modified Metabolites.

Published in:

Molecules, 2017, v. 22, n. 8, p. 1323, doi. 10.3390/molecules22081323

By:

Romanucci, Valeria;
Gravante, Raffaele;
Cimafonte, Martina;
Di Marino, Cinzia;
Mailhot, Gilles;
Brigante, Marcello;
Zarrelli, Armando;
Di Fabio, Giovanni

Publication type:

Article

Silibinin inhibits the production of pro-inflammatory cytokines through inhibition of NF-κB signaling pathway in HMC-1 human mast cells.

Published in:

Inflammation Research, 2013, v. 62, n. 11, p. 941, doi. 10.1007/s00011-013-0640-1

By:

Kim, Beom-Rak;
Seo, Hye-Sook;
Ku, Jin-Mo;
Kim, Gyung-Jun;
Jeon, Chan;
Park, Jong;
Jang, Bo-Hyoung;
Park, Sun-Ju;
Shin, Yong-Cheol;
Ko, Seong-Gyu

Publication type:

Article

Effect of silibinin capsules combined with lifestyle modification on hepatic steatosis in patients with chronic hepatitis B.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80709-z

By:

Lv, Duo-Duo;
Wang, You-Juan;
Wang, Meng-Lan;
Chen, En-Qiang;
Tao, Ya-Chao;
Zhang, Dong-Mei;
Tang, Hong

Publication type:

Article

Preparation, characterisation and biological evaluation of biopolymer-coated multi-walled carbon nanotubes for sustained-delivery of silibinin.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73963-8

By:

Tan, Julia Meihua;
Bullo, Saifullah;
Fakurazi, Sharida;
Hussein, Mohd Zobir

Publication type:

Article

Fabricating niosomal-PEG nanoparticles co-loaded with metformin and silibinin for effective treatment of human lung cancer cells.

Published in:

Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1193708

By:

Salmani-Javan, Elnaz;
Jafari-Gharabaghlou, Davoud;
Bonabi, Esat;
Zarghami, Nosratollah

Publication type:

Article

The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells.

Published in:

Human & Experimental Toxicology, 2017, v. 36, n. 6, p. 573, doi. 10.1177/0960327116658105

By:

Bayram, D.;
Çetin, E. S.;
Kara, M.;
Özgöçmen, M.;
Candan, I. A.

Publication type:

Article