Works matching DE "SIGMA-1 receptor"

Results: 116

Sigma-1 Receptor Rescues Autophagy Through AMPK/mTOR Signaling Pathway in Sepsis-Induced Acute Kidney Injury.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 1917, doi. 10.2147/IJGM.S506593

By:

Jiang, Wei;
Zhang, Jianfeng;
Zhang, Yinan;
Huang, Zhongwei

Publication type:

Article

Phoenix dactylifera L. Pollen and Fluvoxamine Maleate Protect PC12 Cells Against H2O2-Induced Oxidative Stress by Involvement of Nrf2 and SIGMAR1 Gene Expression.

Published in:

Jundishapur Journal of Natural Pharmaceutical Products, 2024, v. 19, n. 1, p. 1, doi. 10.5812/jjnpp-141738

By:

Mazaheri, Elham Lak;
Niknejad, Azadeh;
Amini, Elaheh;
Nabiuni, Mohammad

Publication type:

Article

Cardiac 11C-Donepezil Binding Increases With Age in Healthy Humans: Potentially Signifying Sigma-1 Receptor Upregulation.

Published in:

2019

By:

Horsager, Jacob;
Fedorova, Tatyana D.;
Berge, Nathalie V.D.;
Klinge, Mette W.;
Knudsen, Karoline;
Hansen, Allan K.;
Alstrup, Aage K.O.;
Krogh, Klaus;
Gormsen, Lars;
Borghammer, Per

Publication type:

journal article

Sigma-1 receptor ligand PD144418 and sigma-2 receptor ligand YUN-252 attenuate the stimulant effects of methamphetamine in mice.

Published in:

Psychopharmacology, 2019, v. 236, n. 11, p. 3147, doi. 10.1007/s00213-019-05268-2

By:

Tapia, Melissa A.;
Lever, John R.;
Lever, Susan Z.;
Will, Matthew J.;
Park, Eric S.;
Miller, Dennis K.

Publication type:

Article

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats.

Published in:

Psychopharmacology, 2016, v. 233, n. 7, p. 1269, doi. 10.1007/s00213-016-4209-x

By:

Lenart, Lilla;
Hodrea, Judit;
Hosszu, Adam;
Koszegi, Sandor;
Zelena, Dora;
Balogh, Dora;
Szkibinszkij, Edgar;
Veres-Szekely, Apor;
Wagner, Laszlo;
Vannay, Adam;
Szabo, Attila;
Fekete, Andrea

Publication type:

Article

Sigma 1 receptor activation regulates brain-derived neurotrophic factor through NR2A-CaMKIV-TORC1 pathway to rescue the impairment of learning and memory induced by brain ischaemia/reperfusion.

Published in:

Psychopharmacology, 2015, v. 232, n. 10, p. 1779, doi. 10.1007/s00213-014-3809-6

By:

Xu, Qian;
Ji, Xue-Fei;
Chi, Tian-Yan;
Liu, Peng;
Jin, Ge;
Gu, Shao-Li;
Zou, Li-Bo

Publication type:

Article

Dose-dependent sigma-1 receptor occupancy by donepezil in rat brain can be assessed with C-SA4503 and microPET.

Published in:

Psychopharmacology, 2014, v. 231, n. 20, p. 3997, doi. 10.1007/s00213-014-3533-2

By:

Ramakrishnan, Nisha;
Visser, Anniek;
Schepers, Marianne;
Luurtsema, Gert;
Nyakas, Csaba;
Elsinga, Philip;
Ishiwata, Kiichi;
Dierckx, Rudi;
Waarde, Aren

Publication type:

Article

Successful treatment of chronic knee pain following localization by a sigma-1 receptor radioligand and PET/MRI: a case report.

Published in:

Journal of Pain Research, 2018, v. 11, p. 2353, doi. 10.2147/JPR.S167839

By:

Cipriano, Peter William;
Lee, Sheen-Woo;
Yoon, Daehyun;
Shen, Bin;
Tawfik, Vivianne Lily;
Curtin, Catherine Mills;
Dragoo, Jason L;
James, Michelle Louise;
McCurdy, Christopher Robert;
Chin, Frederick Te-Ning;
Biswal, Sandip

Publication type:

Article

The Effects of Terminal Tagging on Homomeric Interactions of the Sigma 1 Receptor.

Published in:

Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01356

By:

Yano, Hideaki;
Liu, Leanne;
Naing, Sett;
Shi, Lei

Publication type:

Article

Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone.

Published in:

Molecular Pain, 2022, p. 1, doi. 10.1177/17448069211069255

By:

Hornung, Rebecca S;
Raut, Namrata GR;
Cantu, Daisy J;
Lockhart, Lauren M;
Averitt, Dayna L

Publication type:

Article

Dextromethorphan/bupropion in major depressive disorder: a profile of its use.

Published in:

Drugs & Therapy Perspectives, 2023, v. 39, n. 8, p. 270, doi. 10.1007/s40267-023-01009-w

By:

Blair, Hannah A.

Publication type:

Article

The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation.

Published in:

Inflammation Research, 2014, v. 63, n. 3, p. 231, doi. 10.1007/s00011-013-0692-2

By:

Parenti, Carmela;
Marrazzo, Agostino;
Aricò, Giuseppina;
Parenti, Rosalba;
Pasquinucci, Lorella;
Ronsisvalle, Simone;
Ronsisvalle, Giuseppe;
Scoto, Giovanna

Publication type:

Article

Analysis of Sigma-1 Receptor Antagonist BD1047 Effect on Upregulating Proteins in HIV-1-Infected Macrophages Exposed to Cocaine Using Quantitative Proteomics.

Published in:

Biomedicines, 2024, v. 12, n. 9, p. 1934, doi. 10.3390/biomedicines12091934

By:

Vélez-López, Omar;
Carrasquillo-Carrión, Kelvin;
Cantres-Rosario, Yadira M.;
Machín-Martínez, Eraysy;
Álvarez-Ríos, Manuel E.;
Roche-Lima, Abiel;
Tosado-Rodríguez, Eduardo L.;
Meléndez, Loyda M.

Publication type:

Article

The Sigma-1 Receptor Exacerbates Cardiac Dysfunction Induced by Obstructive Nephropathy: A Role for Sexual Dimorphism.

Published in:

Biomedicines, 2024, v. 12, n. 8, p. 1908, doi. 10.3390/biomedicines12081908

By:

Munguia-Galaviz, Francisco Javier;
Miranda-Diaz, Alejandra Guillermina;
Gutierrez-Mercado, Yanet Karina;
Ku-Centurion, Marco;
Gonzalez-Gonzalez, Ricardo Arturo;
Portilla-de Buen, Eliseo;
Echavarria, Raquel

Publication type:

Article

The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65192

By:

Zhemkov, Vladimir;
Ditlev, Jonathon A.;
Wan-Ru Lee;
Wilson, Mikaela;
Liou, Jen;
Rosen, Michael K.;
Bezprozvanny, Ilya

Publication type:

Article

Author Correction: Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization.

Published in:

2021

By:

Chao, Jie;
Zhang, Yuan;
Du, Longfei;
Zhou, Rongbin;
Wu, Xiaodong;
Shen, Kai;
Yao, Honghong

Publication type:

Correction Notice

Sigma-1 receptor agonist fluvoxamine for delirium in older adults.

Published in:

2012

By:

Hashimoto, Kenji;
Furuse, Tsutomu

Publication type:

Opinion

Sigma-1 receptor activation attenuates DOX-induced cardiotoxicity by alleviating endoplasmic reticulum stress and mitochondrial calcium overload via PERK and IP3R-VDAC1-MCU signaling pathways.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00617-y

By:

Li, Zixuan;
Ran, Qian;
Qu, Chuan;
Hu, Shan;
Cui, Shengyu;
Zhou, You;
Shen, Bo;
Yang, Bo

Publication type:

Article

Point Mutation in Sigma-1 Receptor Inhibits Neuronal Cell Differentiation.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A992

By:

Yahong Zhang;
Kim, Felix J.;
Pasternak, Gavril W.

Publication type:

Article

Long-Term Haloperidol Treatment Prolongs QT Interval and Increases Expression of Sigma 1 and IP3 Receptors in Guinea Pig Hearts.

Published in:

Tohoku Journal of Experimental Medicine, 2015, v. 236, n. 3, p. 199, doi. 10.1620/tjem.236.199

By:

Tibor Stracina;
Iva Slaninova;
Hana Polanska;
Martina Axmanova;
Veronika Olejnickova;
Petr Konecny;
Masarik, Michal;
Olga Krizanova;
Marie Novakova

Publication type:

Article

Ayahuasca and its interaction with the sigma-1 receptor: a potential treatment for COVID-19.

Published in:

Brazilian Journal of Psychiatry / Revista Brasileira de Psiquiatria, 2022, v. 44, n. 4, p. 465, doi. 10.47626/1516-4446-2022-2541

By:

Escobar-Cornejo, Guillermo Saúl;
Escobar-Cornejo, Diego Mauricio;
Ramos-Vargas, Luis Fernando

Publication type:

Article

Stalking in clinical psychiatry: when the doctor becomes the victim.

Published in:

Brazilian Journal of Psychiatry / Revista Brasileira de Psiquiatria, 2022, v. 44, n. 4, p. 464, doi. 10.47626/1516-4446-2022-2464

By:

Soledade Signori, João Pedro;
do Canto, Gustavo Cambraia;
Roza, Thiago Henrique;
de Borba Telles, Lisieux Elaine;
de Almeida Fleck, Marcelo Pio

Publication type:

Article

High specific activity tritium labelling of some sigma-1 receptor agonists.

Published in:

Journal of Radioanalytical & Nuclear Chemistry, 2012, v. 292, n. 1, p. 19, doi. 10.1007/s10967-011-1369-3

By:

Ahern, David;
Seguin, Richard;
Filer, Crist

Publication type:

Article

Neurosteroids and neurological disorders.

Published in:

2025

By:

Gi Wan Park;
Hayoung Kim;
Seong Hyun Won;
Nam Hyun Kim;
Sheu-Ran Choi

Publication type:

Literature Review

Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1485337

By:

Chaves, Cristiano;
dos Santos, Rafael G.;
Dursun, Serdar M.;
Tusconi, Massimo;
Carta, Mauro Giovanni;
Brietzke, Elisa;
Hallak, Jaime E. C.

Publication type:

Article

Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1485337

By:

Chaves, Cristiano;
dos Santos, Rafael G.;
Dursun, Serdar M.;
Tusconi, Massimo;
Carta, Mauro Giovanni;
Brietzke, Elisa;
Hallak, Jaime E. C.

Publication type:

Article

Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00678

By:

Cirino, Thomas J.;
Eans, Shainnel O.;
Medina, Jessica M.;
Wilson, Lisa L.;
Mottinelli, Marco;
Intagliata, Sebastiano;
McCurdy, Christopher R.;
McLaughlin, Jay P.

Publication type:

Article

Ligands Exert Biased Activity to Regulate Sigma 1 Receptor Interactions With Cationic TRPA1, TRPV1, and TRPM8 Channels.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00634

By:

Cortés-Montero, Elsa;
Sánchez-Blázquez, Pilar;
Onetti, Yara;
Merlos, Manuel;
Garzón, Javier

Publication type:

Article

Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49894-7

By:

Fu, Chunting;
Xiao, Yang;
Zhou, Xiaoming;
Sun, Ziyi

Publication type:

Article

Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation.

Published in:

Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/265056

By:

Zhu, Shanshan;
Wang, Chenchen;
Han, Yuan;
Song, Chao;
Hu, Xueming;
Liu, Yannan

Publication type:

Article

NMDA Receptors Are Upregulated and Trafficked to the Plasma Membrane after Sigma-1 Receptor Activation in the Rat Hippocampus.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 34, p. 11325, doi. 10.1523/JNEUROSCI.0458-14.2014

By:

Pabba, Mohan;
Wong, Adrian Y. C.;
Ahlskog, Nina;
Hristova, Elitza;
Biscaro, Dante;
Nassrallah, Wissam;
Ngsee, Johnny K.;
Snyder, Melissa;
Beique, Jean-Claude;
Bergeron, Richard

Publication type:

Article

Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice.

Published in:

Molecular Pain, 2014, v. 10, n. 1, p. 1, doi. 10.1186/1744-8069-10-11

By:

Nieto, Francisco R.;
Cendán, Cruz M.;
Cañizares, Francisco J.;
Cubero, María A.;
Vela, José M.;
Fernández-Segura, Eduardo;
Baeyens, José M.

Publication type:

Article

Brighter Outlook.

Published in:: Chemistry & Industry, 2025, v. 89, n. 3, p. 18, doi. 10.1002/cind.10402
Publication type:: Article

Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.

Published in:

Archives of Toxicology, 2024, v. 98, n. 10, p. 3323, doi. 10.1007/s00204-024-03805-3

By:

Chen, Wenying;
Han, Lingyun;
Yang, Ruiran;
Wang, Hongwei;
Yao, Song;
Deng, Huiqiong;
Liu, Shuangchao;
Zhou, Yao;
Shen, Xiao Li

Publication type:

Article

Interaction of Afobazole with Sigma-1 Receptors in the Mouse Brain.

Published in:

Pharmaceutical Chemistry Journal, 2015, v. 49, n. 1, p. 7, doi. 10.1007/s11094-015-1212-1

By:

Abramova, E.;
Voronin, M.;
Seredenin, S.

Publication type:

Article

Interaction of 2-mercaptobenzimidazole derivatives with sigma-1 receptors.

Published in:

Pharmaceutical Chemistry Journal, 2012, v. 46, n. 6, p. 334, doi. 10.1007/s11094-012-0793-1

By:

Ryaskina, E.;
Voronin, M.;
Seredenin, S.

Publication type:

Article

Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([124I]IPAG).

Published in:

2020

By:

Gangangari, Kishore K.;
Váradi, András;
Majumdar, Susruta;
Larson, Steven M.;
Pasternak, Gavril W.;
Pillarsetty, NagaVara Kishore

Publication type:

journal article

Cutamesine Overcomes REM Sleep Deprivation-Induced Memory Loss: Relationship to Sigma-1 Receptor Occupancy.

Published in:

Molecular Imaging & Biology, 2015, v. 17, n. 3, p. 364, doi. 10.1007/s11307-014-0808-2

By:

Ramakrishnan, Nisha;
Schepers, Marianne;
Luurtsema, Gert;
Nyakas, Csaba;
Elsinga, Philip;
Ishiwata, Kiichi;
Dierckx, Rudi;
Waarde, Aren

Publication type:

Article

Altered Sigma-1 Receptor Expression in Two Animal Models of Cognitive Impairment.

Published in:

Molecular Imaging & Biology, 2015, v. 17, n. 2, p. 231, doi. 10.1007/s11307-014-0780-x

By:

Ramakrishnan, Nisha;
Marosi, Krisztina;
Nyakas, Csaba;
Kwizera, Chantal;
Elsinga, Philip;
Ishiwata, Kiichi;
Luiten, Paul;
Dierckx, Rudi;
Waarde, Aren

Publication type:

Article

BENZOMORPHAN AND NON-BENZOMORPHAN AGONISTS DIFFERENTIALLY ALTER SIGMA-1 RECEPTOR QUATERNARY STRUCTURE, AS DOES TYPES OF CELLULAR STRESS.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. 1368, doi. 10.1093/ijnp/pyae059.654

By:

Couly, Simon;
Yuko Yasui;
Semnyonga Foncham;
Grammatikakis, Ioannis;
Lal, Ashish;
Lei Shi;
Tsung-Ping Su

Publication type:

Article

SIGMA-1 RECEPTOR ACTIVATION BY FLUVOXAMINE RESTORES TFEB-MEDIATED AUTOPHAGY VIA NUCLEOPORIN POM121 IN A NSC34 C9ALS/FTD MODEL.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. 1367

By:

Hsiang-En Wu;
Shao-Ming Wang;
Chun-Yu Lin;
Fenf-Ju Weng;
Hsuan-Cheng Wu;
Leeodella Sands;
Tsung-Ping Su

Publication type:

Article

N,N-DIMETHYLTRYPTAMINE, A NATURAL HALLUCINOGEN, AMELIORATES ALZHEIMER'S DISEASE BY RESTORING NEURONAL SIGMA-1 RECEPTOR-MEDIATED ENDOPLASMIC RETICULUM-MITOCHONDRIA CROSSTALK.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. i292, doi. 10.1093/ijnp/pyae059.518

By:

Dan Cheng;
Zhang-Jin Zhang

Publication type:

Article

EXAMINING THE EFFECTS OF SIGMA-1 RECEPTOR AGONISTS ON THE INTRACELLULAR LOCALIZATION OF THE ENDOGENOUS RECEPTOR IN NEURO2A CELLS.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. i278, doi. 10.1093/ijnp/pyae059.493

By:

Yuko Yasui;
Couly, Simon;
Tsung-Ping Su

Publication type:

Article

EFFICACY AND TOLERABILITY OF RISPERIDONE, YOKUKANSAN, AND FLUVOXAMINE FOR THE TREATMENT OF BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS OF DEMENTIA, AND PHARMACOLOGICAL CONSIDERATION.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. i207, doi. 10.1093/ijnp/pyae059.362

By:

Kurita, Masatake;
Satoshi Nishino;
Mika Teranishi;
Kenji Takeyoshi;
Tadahiro Sato;
Yoshiro Okubo;
Tateno, Amane

Publication type:

Article

Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice.

Published in:

International Journal of Neuropsychopharmacology, 2018, v. 21, n. 10, p. 938, doi. 10.1093/ijnp/pyy049

By:

Sánchez-Blázquez, Pilar;
Cortés-Montero, Elsa;
Rodríguez-Muñoz, María;
Garzón, Javier

Publication type:

Article

Why sigma-1 receptor dysfunction might confer vulnerability to cannabis-induced psychosis.

Published in:

International Journal of Neuropsychopharmacology, 2014, v. 17, n. 12, p. 1911, doi. 10.1017/S1461145714000960

By:

Arnold, Jonathon C.

Publication type:

Article

The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.

Published in:

International Journal of Neuropsychopharmacology, 2014, v. 17, n. 12, p. 1943, doi. 10.1017/S1461145714000029

By:

Sánchez-Blázquez, Pilar;
Rodríguez-Muñoz, María;
Herrero-Labrador, Raquel;
Burgueño, Javier;
Zamanillo, Daniel;
Garzón, Javier

Publication type:

Article

Sigma-1 Receptors in Depression: Mechanism and Therapeutic Development.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.925879

By:

Ren, Peng;
Wang, Jingya;
Li, Nanxi;
Li, Guangxiang;
Ma, Hui;
Zhao, Yongqi;
Li, Yunfeng

Publication type:

Article

The Safety Profile of Pridopidine, a Novel Sigma-1 Receptor Agonist for the Treatment of Huntington's Disease: Safety of Pridopidine in Huntington's Disease: Y. P. Goldberg et al.

Published in:

CNS Drugs, 2025, v. 39, n. 5, p. 485, doi. 10.1007/s40263-025-01171-x

By:

Goldberg, Yigal Paul;
Navon-Perry, Leehee;
Cruz-Herranz, Andrés;
Chen, Kelly;
Hecker-Barth, Gabriele;
Spiegel, Katrin;
Cohen, Yael;
Niethammer, Martin;
Tan, Andrew M.;
Schuring, Henk;
Geva, Michal;
Hayden, Michael R.

Publication type:

Article

The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception.

Published in:

Molecular Brain, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13041-020-00676-4

By:

Sánchez-Blázquez, Pilar;
Cortés-Montero, Elsa;
Rodríguez-Muñoz, María;
Merlos, Manuel;
Garzón-Niño, Javier

Publication type:

Article